WO2020139057A3 - Composition for preventing and treating muscle disease or improving muscle function, comprising illicium verum extract or shikimic acid - Google Patents
Composition for preventing and treating muscle disease or improving muscle function, comprising illicium verum extract or shikimic acid Download PDFInfo
- Publication number
- WO2020139057A3 WO2020139057A3 PCT/KR2019/018726 KR2019018726W WO2020139057A3 WO 2020139057 A3 WO2020139057 A3 WO 2020139057A3 KR 2019018726 W KR2019018726 W KR 2019018726W WO 2020139057 A3 WO2020139057 A3 WO 2020139057A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- muscle
- preventing
- shikimic acid
- treating
- composition
- Prior art date
Links
- 240000007232 Illicium verum Species 0.000 title abstract 3
- 235000008227 Illicium verum Nutrition 0.000 title abstract 3
- 208000029578 Muscle disease Diseases 0.000 title abstract 3
- 230000004220 muscle function Effects 0.000 title abstract 3
- JXOHGGNKMLTUBP-HSUXUTPPSA-N shikimic acid Chemical compound O[C@@H]1CC(C(O)=O)=C[C@@H](O)[C@H]1O JXOHGGNKMLTUBP-HSUXUTPPSA-N 0.000 title abstract 3
- JXOHGGNKMLTUBP-JKUQZMGJSA-N shikimic acid Natural products O[C@@H]1CC(C(O)=O)=C[C@H](O)[C@@H]1O JXOHGGNKMLTUBP-JKUQZMGJSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000008934 Muscle Proteins Human genes 0.000 abstract 2
- 108010074084 Muscle Proteins Proteins 0.000 abstract 2
- 206010006895 Cachexia Diseases 0.000 abstract 1
- 102100025014 E3 ubiquitin-protein ligase TRIM63 Human genes 0.000 abstract 1
- 101710164910 E3 ubiquitin-protein ligase TRIM63 Proteins 0.000 abstract 1
- 102100040669 F-box only protein 32 Human genes 0.000 abstract 1
- 101710191029 F-box only protein 32 Proteins 0.000 abstract 1
- 206010028372 Muscular weakness Diseases 0.000 abstract 1
- 102000013530 TOR Serine-Threonine Kinases Human genes 0.000 abstract 1
- 108010065917 TOR Serine-Threonine Kinases Proteins 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001965 increasing effect Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 230000003387 muscular Effects 0.000 abstract 1
- 201000000585 muscular atrophy Diseases 0.000 abstract 1
- 201000006938 muscular dystrophy Diseases 0.000 abstract 1
- 230000036473 myasthenia Effects 0.000 abstract 1
- 238000001243 protein synthesis Methods 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 208000001076 sarcopenia Diseases 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/316—Foods, ingredients or supplements having a functional effect on health having an effect on regeneration or building of ligaments or muscles
Abstract
The present invention relates to a composition for preventing and treating a muscle disease or improving muscle function, comprising an Illicium verum extract and shikimic acid. The Illicium verum extract and shikimic acid according to the present invention have the effect of increasing activity of mTOR involved in muscle protein synthesis and reducing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increase muscle mass and enhance muscle function, thereby being useful for preventing, treating, or alleviating various muscle diseases such as atony, muscular atrophy, muscular dystrophy, muscular degeneration, myasthenia, cachexia, and sarcopenia.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20180172731 | 2018-12-28 | ||
KR10-2018-0172731 | 2018-12-28 | ||
KR1020190076670A KR20200083146A (en) | 2018-12-28 | 2019-06-26 | Composition for prevention and treatment of muscular disorder or improvement of muscular functions comprising Illicium verum extract or shikimic acid |
KR10-2019-0076670 | 2019-06-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2020139057A2 WO2020139057A2 (en) | 2020-07-02 |
WO2020139057A3 true WO2020139057A3 (en) | 2020-08-20 |
Family
ID=71126648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2019/018726 WO2020139057A2 (en) | 2018-12-28 | 2019-12-30 | Composition for preventing and treating muscle disease or improving muscle function, comprising illicium verum extract or shikimic acid |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR102352636B1 (en) |
WO (1) | WO2020139057A2 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007138607A1 (en) * | 2006-05-25 | 2007-12-06 | Iyer Sankar V | Method for obtaining shikimic acid |
JP2009215266A (en) * | 2008-03-12 | 2009-09-24 | Kose Corp | Skin lightening agent containing shikimic acid as beneficial ingredient |
WO2014024140A1 (en) * | 2012-08-08 | 2014-02-13 | Koninklijke Philips N.V. | Led-based phototherapy panel capable of fitting in an x-ray cassette tray of an incubator |
KR20150024606A (en) * | 2013-08-27 | 2015-03-09 | 영남대학교 산학협력단 | Composition for inhibiting cellular senescence comprising extracts of Anisi Stellati Fructus or threo-1(4'-methoxyphenyl)-1,2-propandiol isolated from the same |
KR20150044607A (en) * | 2013-10-17 | 2015-04-27 | (주)아모레퍼시픽 | Method for derivation of inducible Pluripotent stem cells and inducible Pluripotent stem cells produced using the same |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6603133B2 (en) * | 2013-02-06 | 2019-11-06 | ブランダイス ユニバーシティー | Treatment of DNA damage and mitochondrial dysfunction using palm fruit |
-
2019
- 2019-12-30 KR KR1020190178104A patent/KR102352636B1/en active IP Right Grant
- 2019-12-30 WO PCT/KR2019/018726 patent/WO2020139057A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007138607A1 (en) * | 2006-05-25 | 2007-12-06 | Iyer Sankar V | Method for obtaining shikimic acid |
JP2009215266A (en) * | 2008-03-12 | 2009-09-24 | Kose Corp | Skin lightening agent containing shikimic acid as beneficial ingredient |
WO2014024140A1 (en) * | 2012-08-08 | 2014-02-13 | Koninklijke Philips N.V. | Led-based phototherapy panel capable of fitting in an x-ray cassette tray of an incubator |
KR20150024606A (en) * | 2013-08-27 | 2015-03-09 | 영남대학교 산학협력단 | Composition for inhibiting cellular senescence comprising extracts of Anisi Stellati Fructus or threo-1(4'-methoxyphenyl)-1,2-propandiol isolated from the same |
KR20150044607A (en) * | 2013-10-17 | 2015-04-27 | (주)아모레퍼시픽 | Method for derivation of inducible Pluripotent stem cells and inducible Pluripotent stem cells produced using the same |
Also Published As
Publication number | Publication date |
---|---|
KR20200083354A (en) | 2020-07-08 |
WO2020139057A2 (en) | 2020-07-02 |
KR102352636B1 (en) | 2022-01-19 |
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