WO2020120193A1 - Système de désinfection - Google Patents

Système de désinfection Download PDF

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Publication number
WO2020120193A1
WO2020120193A1 PCT/EP2019/083277 EP2019083277W WO2020120193A1 WO 2020120193 A1 WO2020120193 A1 WO 2020120193A1 EP 2019083277 W EP2019083277 W EP 2019083277W WO 2020120193 A1 WO2020120193 A1 WO 2020120193A1
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WO
WIPO (PCT)
Prior art keywords
disinfectant
wipes
wipe
disinfectant composition
weight
Prior art date
Application number
PCT/EP2019/083277
Other languages
English (en)
Inventor
Raymond Chambers
Original Assignee
Medentech Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medentech Limited filed Critical Medentech Limited
Publication of WO2020120193A1 publication Critical patent/WO2020120193A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B1/00—Cleaning by methods involving the use of tools
    • B08B1/10—Cleaning by methods involving the use of tools characterised by the type of cleaning tool
    • B08B1/14—Wipes; Absorbent members, e.g. swabs or sponges
    • B08B1/143—Wipes

Definitions

  • biocidal wipes which are commercially available. Such wipes contain various active agents such as peracetic acid, alcohol, quaternary ammonium compounds, and chlorine- based compounds such as bleach.
  • Wipes containing alcohol or quaternary ammonium compounds have a narrow spectrum of activity. They are also not sporicidal and therefore have limited efficacy against important human pathogens such Clostridium difficile.
  • Liquid hydrogen peroxide is unstable and decomposes quickly. In addition, the stability of this biocide is greatly affected by temperature. Hydrogen peroxide is also highly corrosive and produces oxygen as a by-product; which corrodes iron containing metals.
  • PAA Peracetic acid
  • TAED tetraacetylethylenediamine
  • PAA solutions and wipes provide a very unpleasant odour.
  • NIOSH National Institute for Occupational Safety and Health
  • Bleach solutions are highly corrosive and have poor residual killing powder.
  • W089/05093A describes a wipe comprising a lofted non-woven substrate having solid particles of a chlorine release agent such as sodium dichloroisocyanurate (NaDCC) entrapped within its structure.
  • a chlorine release agent such as sodium dichloroisocyanurate (NaDCC) entrapped within its structure.
  • NaDCC sodium dichloroisocyanurate
  • W090/02166A describes a system in which NaDCC particles are retained in an adhesive polymer which is used to bond layers of a substrate/wipe.
  • GB2439059A describes a wipe package comprising a first compartment containing a dry wipe impregnated with a dichloroisocyanurate and a second compartment containing an activating liquid that is released when a barrier between the compartments is ruptured.
  • US5,814,159 describes a cleaning kit comprising a stack of wipes packaged with a container of cleaning fluid. The wipes are exposed to the chemicals in the cleaning fluid just before use - when the cleaning fluid is released from the container.
  • This invention is directed towards providing a system which will overcome this problem.
  • the invention provides wipes with a dry disinfectant composition
  • a dry disinfectant composition comprising NaDCC as a disinfectant agent, an effervescent base, and a surfactant.
  • NaDCC sodium dimethyl methacrylate
  • hypochlorous acid dissociates in water to form the hypochlorite (CIO-) anion.
  • Chlorine becomes less effective with increasing pH (Hurst, 2001).
  • the disinfection powder used in the invention includes an effervescent base that we believe increases the acidity of solutions.
  • hypochlorous acid generated from the NaDCC is predominantly in the undissociated state (HOC1).
  • hypochlorite solutions are alkaline, which increases pH and reduces the effectiveness of the chlorine solution (Macedo and Barra, 2002). Therefore, the effervescent base increases the efficacy of the hypochlorous acid solution.
  • the effervescent system allows the quick dissolution of the disinfectant powder and facilitates the quick distribution of NaDCC into the wipe substrate.
  • Biofilms are a major problem in the hospital, agriculture, water and food processing sectors. They have been associated with the spread of hospital acquired infections (HAI’s). Moreover, they have been linked with the persistence and spread of multi drug resistant organisms (MDRO’s).
  • the formulation used in the invention contains a surfactant.
  • the surfactant assists in penetrating, breaking-up and dispersing biofilms. This facilitates the removal of biofilm and reduces the persistence of pathogenic bacteria.
  • the presence of bioburden and organic material will inactivate biocides. Therefore, a cleaning step always precedes a disinfection step. This is the case in the hospital, agriculture, water and food processing sectors.
  • the cleaning step requires a detergent product.
  • the formulation of the invention contains a surfactant and the formulation acts both as a cleaner and a disinfectant. Therefore, a user only requires one product to achieve both applications. This ultimately saves the user both time and money.
  • the surfactant may be an anionic surfactant such as sodium dodecylbenzene sulphonate.
  • the surfactant may comprise from 1% to 13% by weight of the disinfectant composition.
  • the surfactant may comprise 2% to 12%, in one case about 2% by weight of the disinfectant composition.
  • a reduced level of surfactant improves dissolution time and reduces the amount of foam formed during activation without negatively impacting biofilm efficacy.
  • the disinfectant agent is a chlorinating agent. It is particularly preferred that the chlorinating agent is sodium dichloroisocyanurate.
  • the disinfectant agent may be present in an amount of from 40% to 60% by weight of the composition. The disinfectant agent may be present in an amount of about 50% by weight of the composition.
  • the effervescent base comprises an aliphatic carboxylic acid or an acid salt thereof and an alkali metal bicarbonate.
  • the aliphatic carboxylic acid may be adipic acid.
  • the aliphatic carboxylic acid may comprise from 20% to 30% by weight of the disinfectant composition.
  • the aliphatic carboxylic acid may comprise about 23% by weight of the disinfectant composition.
  • the alkali metal bicarbonate may be sodium bicarbonate.
  • the alkali metal bicarbonate may comprise from 10% to 30% by weight of the disinfectant composition.
  • the alkali metal bicarbonate may comprise about 21% by weight of the disinfectant composition.
  • the disinfectant composition may comprise an alkali metal carbonate.
  • the alkali metal carbonate may comprise sodium carbonate.
  • the alkali metal carbonate may comprise from 2% to 8% by weight of the disinfectant composition.
  • the alkali metal carbonate may comprise about 3.9% by weight of the disinfectant composition.
  • the invention also provides a disinfectant system comprising a plurality of wipes having a dry disinfectant composition dispersed in or on each wipe, and an outer housing containing the wipes, the housing having a dispensing opening for withdrawing a wipe from the housing.
  • the wipe comprises a plurality of layers including a top layer, a bottom layer and at least one intermediate layer and wherein the dry disinfectant powder is dispersed over only the intermediate layer(s).
  • the wipe comprises a number of sections which are folded over to form the layers.
  • the wipe may comprise four quadrants which are folded to form the top, bottom and intermediate layers.
  • the dry disinfectant powder may be applied to only one of the quadrants.
  • the plurality of wipes are arranged in a stack of individual wipes.
  • Additional dry disinfectant powder may be applied to a top and/or a bottom of the stack.
  • the invention also provides a disinfectant system comprising:- i. a plurality of wipes having a dry disinfectant composition dispersed in or on each wipe; ii. a container for liquid, the liquid being releasable from the container to activate the disinfectant composition; and
  • the wipe comprises a plurality of layers including a top layer, a bottom layer and at least one intermediate layer and wherein the dry disinfectant powder is dispersed over only the intermediate layer(s).
  • the wipe comprises a number of sections which are folded over to form the layers.
  • the wipe may comprise four quadrants which are folded to form the top, bottom and intermediate layers.
  • the dry disinfectant powder may be applied to only one of the quadrants.
  • the plurality of wipes are arranged in a stack of individual wipes.
  • Additional dry disinfectant powder may be applied to a top and/or a bottom of the stack.
  • the additional dry disinfectant composition applied to the top and/or bottom of the stack of wipes ensures a more even distribution of chlorine in the system.
  • the disinfectant agent is a chlorinating agent.
  • the chlorinating agent is sodium dichloroisocyanurate.
  • distribution of the chlorinating agent, when activated, may be enhanced.
  • chlorinating agents include NaDCC dihydrate and Tricholoroisocyanuric acid (TCCA).
  • Anhydrous NaDCC has more available chlorine (approx. 62.0%) for disinfection than dihydrate NaDCC (approx. 56.0%).
  • dihydrate NaDCC approximately 5 mM KCl
  • anhydrous NaDCC is more soluble than the dihydrate form. Therefore, it will have a quicker dissolution and substrate absorption rate.
  • dihydrate NaDCC can be used as a chlorine donor, it is not the preferred option.
  • TCCA Terichloroisocyanuric acid
  • the housing is adapted to orientate the dispensing opening in a substantially vertical plane.
  • the housing may comprise a base support.
  • the wipes comprise non-woven polymeric fibres such as polypropylene fibres.
  • the liquid is water.
  • the system may further comprise a holder for the housing, the holder being adapted to orientate the wipes substantially vertically.
  • the invention also provides a method for activating a disinfectant system of the invention comprising the steps of:- rupturing a container to release the liquid;
  • the dry disinfectant formulation may be in a powder firm with an average grain size of from 1 to 1200 pm.
  • Figs. 1 to 3 are a series of drawings illustrating the folding of a wipe
  • Figs. 4 to 6 are a series of drawings illustrating the folding of another wipe
  • Fig. 7 is an illustration of a repeating unit of the folded wipes of Figs. 3 and 6;
  • Fig. 8 is a drawing of a stack of wipes formed from the folded wipes of Figs. 3 and 6;
  • Fig. 9 illustrates a disinfectant system comprising a plurality of wipes, a container for liquid and an outer housing for the wipes and the container;
  • Fig. 10 is an illustration of the outer housing
  • Figs. 11 to 14 are a series of drawings illustrating activation of the wipes
  • Fig. 15 illustrates a stand and a package of wipes
  • Fig. 16 is a chart of chlorine distribution through a package of wipes
  • Figs. 17 and 18 illustrate deposition of a dry disinfectant composition on a wipe
  • Fig. 19 illustrates a stack of wipes with a container for liquid
  • Fig. 20 illustrates an outer housing for the stack of wipes and container of Fig. 19;
  • Figs. 21 and 22 are cross sectional views of a stack of wipes, a container for liquid and an outer housing;
  • Fig. 23 and 24 illustrate deposition of a dry disinfectant composition on a wipe
  • Fig. 25 illustrates a stack of wipes
  • Fig. 26 illustrates an outer housing for the stack of wipes
  • Figs. 27 and 28 are cross sectional views of a stack of wipes and an outer housing.
  • a dry formulation comprising a disinfecting agent, a surfactant and an effervescent base is prepared from the following (% by weight):
  • Adipic acid 23.34%
  • Sodium dichloroisocyanurate is a disinfectant agent.
  • Sodium dodecylbenzene sulphonate is a surfactant.
  • Sodium bicarbonate and sodium carbonate are the source of carbon dioxide in the effervescent formula.
  • Adipic acid is a key component of the acid-base effervescent reaction. Once in contact with moisture, the adipic acid reacts with the carbonate salts to produce carbon dioxide gas.
  • the formulation is in a powder form with an average grain size of from 1 - 1200 pm.
  • the formulation is dry mixed and remains stable for 2 years when stored at 5-40°C/65% relative humidity. Stability is also maintained at relative humidity levels of 75%.
  • the primary substrate is preferably polypropylene (100%) non-woven lint-free wipes. Lint may assist in transfer of infection. Propylene wipes have good absorption and mechanical properties and facilitate release of biocide to the surface of the wipe. Polyethylene non-woven lint-free wipes also provide similar advantages.
  • substrates may also be used such as 30, 50 or 70% polyethylene or polypropylene.
  • a biodegradable substrate such as viscose (30, 50, 70 and 100%), rayon (30, 50, 70 and 100%) and cellulose (30, 50, 70 and 100%) may also be used.
  • Various blends may also be used as substrates such as viscose (50%)/polyester (50%), viscose (20%)/polyethylene (35%) and polypropylene (85%)/viscose (15%).
  • the wipes preferably are 25 to lOOgsm.
  • One example is a 26gsm polypropylene medium task wipe such as available from Quattro.
  • the wipe 1 is divided into a number of sections, in this case four quadrants A, B, C, D.
  • the wipe 1 is folded as illustrated so that quadrant C and D are folded over A and B respectively.
  • the disinfection powder (for example an amount of about 0.3g) is applied to quadrant D (which lies on top of B) in this example as illustrated in Fig. 2.
  • the wipe is then folded as illustrated so that quadrant C is folded over D so that the wipe has four quadrants on top of one another with the quadrant D to which the disinfection composition has been applied on the second layer from the bottom as shown in Fig. 3.
  • the wipe 21 is divided into a number of sections, in this case four quadrants A, B, C, D.
  • the wipe 21 is folded as illustrated so that quadrant C and D are folded over A and B respectively.
  • the disinfection powder (for example an amount of about 0.3g) is applied to quadrant C (which lies on top of A) in this example as illustrated in Fig. 5.
  • the wipe is then folded as illustrated so that quadrant D is folded over C so that the wipe has four quadrants on top of one another with the quadrant C to which the disinfection composition has been applied on the second layer from the bottom as illustrated in Fig. 6.
  • the wipe pack consists of 7 horizontally stacked repeating units.
  • a repeating unit consists of wipe 1 on the bottom layer and wipe 21 on the top layer.
  • a single wipe 1 is stacked horizontally on top of the repeating units.
  • the final wipe pack as illustrated in Fig. 8 consists of 15 wipes.
  • a suitable cracking bag 2 is a low-density polypropylene/polyethylene bag is filled with an activating liquid which in this case is water.
  • the cracking bag may contain 210ml deionised 3 ⁇ 40 for activating a plurality of wipes containing 4.5g in total of disinfecting powder.
  • a suitable outer housing is of a flexible material such as low-density polypropylene/polyethylene outer housing 3 having an outlet opening 4 which may be covered by removable flap or lid.
  • a plurality of wipes 1 prepared as outlined above are stacked to form a wipe stack 10 which may contain 15 wipes, by way of example.
  • the housing 3 contains the cracking bag 2.
  • An additional amount of disinfectant powder 11 (such as 0.3g) is placed on top of the cracking bag 2.
  • the wipe stack 10 may be placed in the housing 3 on top of the cracking bag 2 as illustrated in Fig. 9.
  • a further additional amount of disinfectant powder 12 (such as 0.3g) may be placed on top of the wipe stack 10.
  • the housing 3 is then sealed.
  • the housing 3 is also shown in Fig. 10.
  • Fig. 11 To activate the wipes for use hand pressure (Fig. 11) is first applied to the outer housing sufficient to cause the cracking bag 2 to burst and release water. The housing is then manually rotated (Fig. 12) about its horizontal and vertical axis for approximately 10 seconds. This is the initial priming phase. To activate the dissolution of the disinfectant powder and ensure an even chlorine distribution, the unit is placed horizontally with face Xi in contact with a flat surface (Fig. 13). The unit is kept in this orientation for a period such as 3 minutes. Following this standing period, the unit is rotated and placed horizontally with face X2 in contact with the flat surface (Fig. 14). The unit is kept in this orientation for a further period such as 3 minutes.
  • each wipe is saturated with deionised water and full dissolution of powder has occurred.
  • the NaDCC is immediately activated by the deionised water.
  • the activated NaDCC forms the powerful biocide hypochlorous acid, which is distributed equally in every wipe.
  • the housing system is stored vertically such that the outlet 4 for the wipes is located in a vertical plane.
  • the housing containing the activated wipes is then placed in a suitable standing rack 20 which retains the housing in the desired vertical orientation as illustrated in Fig. 15.
  • the disinfectant system was set up and activated as outlined above.
  • Step 2 was repeated for each wipe, and the free chlorine distribution within the disinfectant system was examined.
  • Steps 1 - 3 were repeated to examine the chlorine distribution and residual chlorine concentration of the system following 72 hours storage in the vertical plane.
  • each wipe in the disinfection system had levels of free chlorine between 5382 - 8074 ppm. As shown in Table 1, the average free chlorine concentration within the system is 6758 ppm (Standard deviation (SD): 784.01, coefficient of variation (CV): 11.60%. The target free chlorine concentration for each wipe is 6910 ppm. No wipe had a % difference (see Eqn 1.1) from the mean greater than 20.5%. Moreover, the free chlorine concentration was maintained in each wipe for a period up to 72 hours. The target free chlorine concentration in each wipe is 6910 ppm. The % difference of the average from the target was less than 2.25% (see Eqn 1.2).
  • FIGs. 17 to 22 there is illustrated another disinfectant system comprising a plurality of wipes with a dry disinfectant powder as described above deposited on the wipes.
  • a typical dose is 0.15g.
  • the wipes 30 are not folded and the disinfectant powder 31 is deposited in the centre of the wipe as illustrated in figs, 17 and 18.
  • the wipe is 23.5cm x 13cm and the disinfectant is deposited in a central area which may be 5cm x 1cm.
  • the wipes are then stacked one upon the other as illustrated in Fig. 19.
  • An additional dose 35, 36 of the disinfectant composition is deposited in this case below 35 and above 36 the stack of wipes.
  • These reservoir/booster doses 35 and/or 36 of disinfectant composition ensure that the desired free chlorine concentration is maintained throughout the pack of wipes when the system has been activated.
  • a cracking bag 40 containing water is placed on top of the stack of wipes and the stack of wipes and cracking bag 40 are placed in an outer housing/package as described above and illustrated in Figs. 21 and 22.
  • the outer housing/package 45 has an opening 46 through which a wipe may be withdrawn, as required. The opening may be closed by a suitable flap or lid.
  • Another disinfectant system is illustrated in Figs. 23 to 28.
  • the system comprising a plurality of wipes 50 with a dry disinfectant powder 51 as described above deposited on the wipes.
  • a typical dose is 0.15g.
  • the wipes 50 are not folded and the disinfectant powder 51 is deposited in the centre of the wipe as illustrated in Figs. 23 and 24.
  • the wipe is 23.5cm x 13cm and the disinfectant is deposited in a central area which may be 5cm x 1cm.
  • the wipes 50 are then stacked one upon the other as illustrated in Figs. 25 and 26.
  • An additional dose 55, 56 of the disinfectant composition is deposited in this case below 55 and above 56 the stack of wipes (Fig. 26).
  • These reservoir/booster doses 55 and/or 56 of disinfectant composition ensure that the desired free chlorine concentration is maintained throughout the pack of wipes when the system has been activated.
  • the stack of wipes are placed in an outer housing/package 65 has an opening 66 through which a wipe may be withdrawn, as required. The opening may be closed by a suitable flap or lid.
  • a disinfectant system comprising a plurality of dry wipes was tested. Each wipe had a planar configuration and was layered with a single solid dose of disinfectant.
  • the disinfectant composition comprised of sodium dichloroisocyanurate (50%), adipic acid (23.34%), sodium bicarbonate (20.79%), sodium carbonate (3.87%) and sodium dodecylbenzene sulphonate (2%).
  • a stack of wipes was created whereby one single planar wipe was layered on top of another as illustrated in Figs. 23 to 28.
  • a single dose of disinfectant (0.15 g) was added to the centre of each wipe as illustrated in Figs. 23 and 24. Then a stack of wipes was created whereby one single planar wipe (containing dose) was layered on top of the other as illustrated in Fig. 25.
  • the disinfectant system was housed in an outer polypropylene packaging 65.
  • the top layer of the outer packaging contained a resealable opening 66.
  • a single dose (0.15 g) 55 of disinfectant was applied to the bottom layer of the packaging. It was located on the centre of the bottom layer.
  • a second dose (0.15g) 56 was centrally located on the wipe at the top of the stack as illustrated in Fig. 26.
  • each wipe delivered a biocidal solution with a minimum of 4306 ppm free chlorine.
  • Each wipe is capable of delivering the appropriate strength of biocide for up to 72 hours. This can be extended up to 7 days when using deionised water.
  • each wipe delivers a biocidal solution with a minimum of 4306 ppm free chlorine.
  • the disinfectant composition kills Clostridium difficile in four minutes.
  • the disinfectant system was activated using the following mechanism:
  • the seal was removed from the opening 66. Then 157 ml of tap water was manually added to the device via the opening 66. The seal was then placed back on the opening 66.
  • the system was then activated by rotating the bag along its vertical and horizontal axis for 10 seconds (Fig 12). Following this, the system was placed horizontally with face XI on a flat surface for 3 minutes (Fig. 13). After the system was place on the opposite side (face X2) for a further 3 minutes (Fig. 14). The activation phase allowed complete dissolution of the dose and the equal distribution of the biocide throughout the wipe pack.
  • the system was placed in a container in a vertical position as illustrated in Fig. 15.
  • the vertical storage position ensured that an equal distribution of free chlorine was maintained throughout the wipe pack.
  • a set of five systems was activated simultaneously. At time zero, a single pack was removed and the distribution of free chlorine within the system was examined. This involved the manual extraction of liquid from each wipe. Then the free chlorine concentration of the biocidal solution was determined via iodometric titration. This was repeated for 1, 2, 3, 5 and 7 days.
  • each wipe is loaded with a predefined amount of disinfectant powder.
  • disinfectant powder is placed below and on top of the wipe stack.
  • the amount of powder is based on the saturation level of the wipe substrate (i.e. the amount of liquid a wipe can absorb).
  • the unique loading pattern ensures that each wipe is fully saturated with deionised water. In addition, the loading pattern ensures full powder dissolution and that each wipe absorbs an equal amount of free chlorine during activation.
  • the dry powder within the disinfectant system is kept in an inert state. While in the inert state, the disinfectant powder has a shelf life of at least 24 months.
  • the cracking bag activation system allows the disinfectant powder to stay in an inert state until required for use. Once activated, the disinfectant powder is dissolved in deionised 3 ⁇ 40 and NaDCC is converted to the active biocide hypochlorous acid and the biodegradable by-product cyanuric acid. Maintenance of the disinfectant powder in the dry inert state, allows the system to have a far superior shelf life to that of liquid chlorine products such as sodium hypochlorite.
  • the activation mechanism involves repeated inversions of the system to ensure each wipe is saturated with deionised H 2 0. This step allows the quick and full dissolution of the disinfectant powder and rapid uptake into each wipe. The full dissolution and rapid uptake ensure that each wipe contains an equal concentration of the disinfectant solution.
  • the inversion times and distribution of disinfectant powder within the system have been optimized to ensure full dissolution and an equal distribution of chlorine.
  • Chlorine based wipe systems are known to form concentration gradients, thereby becoming ineffective disinfectant systems.
  • the disinfection system of the invention and its activation method prevent a chlorine concentration gradient from occurring. Therefore, each wipe within the system contains the necessary biocidal concentration to effectively disinfectant surfaces.
  • the rack maintains the system in a vertical plane and prevents the formation of a chlorine concentration gradient occurring during storage.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

La présente invention concerne un système de désinfection comprenant une pluralité de lingettes (1, 21) ayant une composition désinfectante sèche dispersée dans ou sur chaque lingette. La composition désinfectante comprend du NaDCC, une base effervescente et un tensioactif. Le système peut également comprendre un récipient (2) pour liquide lequel peut être libéré afin d'activer la composition désinfectante.
PCT/EP2019/083277 2018-12-14 2019-12-02 Système de désinfection WO2020120193A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18212784 2018-12-14
EP18212784.5 2018-12-14

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WO2020120193A1 true WO2020120193A1 (fr) 2020-06-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113237179A (zh) * 2021-06-24 2021-08-10 河南省肿瘤医院 一种多人病房空气净化系统及方法

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WO1989005093A1 (fr) 1987-11-28 1989-06-15 Fibre Treatments (Holdings) Limited Article de nettoyage
EP0351907A2 (fr) * 1988-07-19 1990-01-24 Unilever N.V. Serviette antivirale
WO1990002166A1 (fr) 1988-08-23 1990-03-08 Fibre Treatments (Holdings) Limited Tissu desinfectant ou blanchissant
US5814159A (en) 1995-03-10 1998-09-29 The Texwipe Company Llc Cleaning method
WO2000007561A1 (fr) * 1998-08-07 2000-02-17 Unilever Plc Coussinet cosmetique effervescent nettoyant
US20060124476A1 (en) * 2004-12-14 2006-06-15 Illinois Tool Works, Inc. Point of use cleaning solution
GB2439059A (en) 2006-06-12 2007-12-19 Agma Ltd Sterile wipe package

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WO1989005093A1 (fr) 1987-11-28 1989-06-15 Fibre Treatments (Holdings) Limited Article de nettoyage
EP0351907A2 (fr) * 1988-07-19 1990-01-24 Unilever N.V. Serviette antivirale
WO1990002166A1 (fr) 1988-08-23 1990-03-08 Fibre Treatments (Holdings) Limited Tissu desinfectant ou blanchissant
US5814159A (en) 1995-03-10 1998-09-29 The Texwipe Company Llc Cleaning method
WO2000007561A1 (fr) * 1998-08-07 2000-02-17 Unilever Plc Coussinet cosmetique effervescent nettoyant
US20060124476A1 (en) * 2004-12-14 2006-06-15 Illinois Tool Works, Inc. Point of use cleaning solution
GB2439059A (en) 2006-06-12 2007-12-19 Agma Ltd Sterile wipe package

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CN113237179B (zh) * 2021-06-24 2022-07-22 河南省肿瘤医院 一种多人病房空气净化系统及方法

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