WO2020111173A1 - Grip, and syringe system and prefilled syringe having same - Google Patents

Grip, and syringe system and prefilled syringe having same Download PDF

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Publication number
WO2020111173A1
WO2020111173A1 PCT/JP2019/046528 JP2019046528W WO2020111173A1 WO 2020111173 A1 WO2020111173 A1 WO 2020111173A1 JP 2019046528 W JP2019046528 W JP 2019046528W WO 2020111173 A1 WO2020111173 A1 WO 2020111173A1
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WO
WIPO (PCT)
Prior art keywords
grip
wall portion
barrel
end wall
syringe
Prior art date
Application number
PCT/JP2019/046528
Other languages
French (fr)
Japanese (ja)
Inventor
竹本昌史
松本二三也
Original Assignee
テルモ株式会社
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Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Publication of WO2020111173A1 publication Critical patent/WO2020111173A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details

Definitions

  • the present invention relates to a grip attached to a barrel of a medical syringe, a syringe system including the grip, and a prefilled syringe.
  • a syringe used for administering a drug solution or the like to a patient, in order to facilitate grasping and operation of the syringe by a user, the syringe is protruded outward at a proximal end of a barrel forming a barrel of the syringe.
  • a grip finger grip
  • WO 2017/170500 discloses a grip attached to a flange formed at the base end of a barrel. The grip is provided with a circular barrel mounting portion for mounting on the outer peripheral surface of the barrel when mounting on the flange.
  • the grip has a narrow part that is narrower than the diameter of the barrel so that it does not accidentally come off from the state of being attached to the barrel and fall. Holds the barrel in a narrow space.
  • the grip is elastically deformed by widening the narrow portion to the diameter of the barrel.
  • an object of the present embodiment is to provide a grip capable of preventing breakage at the time of barrel mounting, a syringe system including the grip, and a prefilled syringe.
  • One aspect of the present invention is a grip mounted on a syringe including a barrel having an outwardly projecting flange provided at a base end portion thereof, and a plunger rod inserted into the barrel, the tip wall portion being a grip.
  • two finger hooks extending from the side of the base portion in a direction substantially perpendicular to the central axis in directions opposite to each other with the central axis interposed therebetween.
  • a flange mounting groove that has an insertion opening that opens in an opening direction that is substantially perpendicular to the extension direction of the two finger hooks, and that is sandwiched between the tip wall portion and the base end wall portion and into which the flange can be inserted.
  • the intermediate portion is provided, and the tip wall portion penetrates the tip wall portion along the central axis, communicates with the flange mounting groove, and is opened in the opening direction on an outer peripheral surface of the barrel.
  • a barrel mounting portion that can be mounted, and the base end wall portion penetrates the base end wall portion along the central axis and is in communication with the flange mounting groove, and is an insertion hole through which the plunger rod can be inserted.
  • the grip extends from the insertion hole in the direction away from the central axis so as to disperse the stress applied to the central portion of the closed end.
  • Another aspect of the present invention is a syringe system including the grip of the above aspect and a syringe.
  • Yet another aspect of the present invention is a grip of the above viewpoint, a syringe having a flange formed at the base end, a piston slidably inserted into the barrel of the syringe, and the piston in the distal direction.
  • Prefilled comprising: the plunger rod for pressing toward and a liquid medicine filled in a liquid chamber defined by the barrel and the piston, wherein the grip is attached to the flange of the syringe. It's in a syringe.
  • FIG. 2A is a perspective view of the grip according to the first embodiment
  • FIG. 2B is a plan view showing the grip of FIG. 2A as viewed from the base end side
  • 3A is a bottom view showing the grip of FIG. 2A as seen from the tip side
  • FIG. 3B is a sectional view taken along line IIIB-IIIB of FIG. 3A.
  • FIG. 5A is a sectional view showing a deformed state of the distal end wall portion when the syringe is mounted
  • FIG. 5B is a sectional view showing a deformed state of the proximal end wall portion when the syringe is mounted. It is a perspective view of a syringe system equipped with a grip according to the first embodiment.
  • 7A is a perspective view of the grip according to the second embodiment, and FIG. 7B is a plan view showing the grip of FIG. 7A as seen from the base end side.
  • FIG. 8A is a perspective view of a grip according to the third embodiment, and FIG. 8B is a plan view showing the grip of FIG. 8A as seen from the base end side.
  • 9A is a perspective view of the grip according to the fourth embodiment, and FIG. 9B is a plan view showing the grip of FIG. 9A as viewed from the base end side.
  • the prefilled syringe 10 includes a syringe 12 and a grip 14 attached to the syringe 12.
  • the prefilled syringe 10 is provided as a product in a state in which the syringe 12 is prefilled with the drug solution M.
  • the syringe 12 includes a hollow barrel 16 that forms the body of the syringe 12, a drug solution M filled in the barrel 16, a gasket 18 inserted in the barrel 16, and a needle provided at the tip of the barrel 16.
  • the holding unit 20 and the cap 22 attached to the needle holding unit 20 are provided. When the syringe 12 is used, the cap 22 is removed and a puncture needle (not shown) is attached to the needle holding portion 20 to be assembled into an injection device.
  • the barrel 16 is a hollow body having a substantially cylindrical shape and having a base end opening 17 at the base end.
  • a flange 24 is formed on the outer peripheral portion of the base end of the barrel 16 so as to project radially outward.
  • a gasket 18 is inserted into the barrel 16 via a base end opening 17. The base end side of the barrel 16 is liquid-tightly sealed by the gasket 18, and the chemical liquid M is sealed in the barrel 16.
  • the gasket 18 is made of, for example, an elastic material such as a rubber material.
  • the outer periphery of the gasket 18 is in liquid-tight contact with the inner peripheral surface of the barrel 16 and is slidably arranged in the barrel 16.
  • the distal end portion 27 of the plunger rod 26 is connected to the gasket 18.
  • the gasket 18 and the tip portion 27 form a piston 19.
  • the plunger rod 26 may be connected to the gasket 18 when a puncture needle (not shown) is attached to the syringe 12 to administer the drug solution M to the patient.
  • the needle holder 20 is formed integrally with the tip of the barrel 16. As shown in FIG. 6, the nozzle 20a extending from the center of the tip of the barrel 16 toward the tip of the barrel 16 in the tip direction (Z1 direction) and the female screw formed so as to surround the outer periphery of the nozzle 20a. And a section 20b. At the time of transportation and storage, the cap 22 is attached to the female screw of the needle holding portion 20 as shown in FIG. At the time of use, the cap 22 is removed and a puncture needle (not shown) is attached to the needle holder 20.
  • the grip 14 is attached to the outer peripheral portion of the base end of the barrel 16 in the product providing state of the prefilled syringe 10. It should be noted that in the product providing state of the prefilled syringe 10, the grip 14 may be separated from the syringe 12 and attached to the outer peripheral portion of the proximal end of the barrel 16 when used by the user.
  • the central axis a in FIG. 2A is simply referred to as “axis a”, and the extending direction of the axis a is referred to as “axial direction”.
  • the axis a of the grip 14 is located on the same straight line as the central axis of the syringe 12 when the grip 14 is attached to the syringe 12.
  • the grip 14 is configured so that the plunger rod 26 can be inserted therethrough.
  • the grip 14 has a base portion 31 having a pair of finger hooks 30.
  • the base portion 31 is a portion that constitutes the central portion of the grip 14 in the axial direction, and is formed in a plate shape orthogonal to the axis a of the grip 14. Therefore, the base portion 31 has a thickness in the axial direction of the grip 14.
  • the pair of finger hooks 30 of the base portion 31 are orthogonal to the axis a and project in opposite directions.
  • the shape of the base portion 31 as viewed from the axial direction is relatively long in the protruding direction of the finger hanging portion 30 and short in the direction orthogonal to the protruding direction.
  • the pair of finger hooks 30 project outward from the flange 24.
  • the base portion 31 includes a plate-shaped tip end wall portion 32 formed on the tip end side, a base end wall portion 34 arranged to face the base end side of the tip end wall portion 32, a tip end wall portion 32, and a base end wall portion 34. And an intermediate portion 36 that connects the and.
  • a flange mounting groove 40 into which the flange 24 can be inserted is formed in the intermediate portion 36.
  • the tip wall portion 32 is formed with a protrusion 58 protruding toward the tip side (Z1 direction) and a barrel mounting portion 42 that can be mounted on the outer peripheral surface of the barrel 16.
  • the protrusion 58 is formed so as to extend in an arc shape in the circumferential direction around the axis a. That is, the protruding portion 58 is formed in a shape (C-shaped cross section) in which a circular ring shape is partially cut out.
  • the cutout portion of the protrusion 58 forms a part of the mounting slit 60 and extends to one side (also referred to as “opening side” or “X1 direction side”) of the distal end wall portion 32 in the short direction.
  • the barrel mounting portion 42 is configured by the inner peripheral side of the protruding portion 58, and penetrates the tip wall portion 32 in the axial direction to communicate with the flange mounting groove 40.
  • the barrel mounting portion 42 is formed as a circumferential surface having an inner diameter equal to or close to the outer diameter of the barrel 16 so that the barrel mounting portion 42 can be mounted on the outer peripheral surface of the barrel 16 (see FIG. 1 ). Further, the barrel mounting portion 42 is open to the opening side (X1 direction side) via the mounting slit 60.
  • the mounting slit 60 is a gap that connects the barrel mounting portion 42 and the outside of the grip 14 and vertically cuts the tip wall portion 32 in the axial direction.
  • the opening width of the mounting slit 60 increases in the opening direction (X1 direction) of the distal end wall portion 32. Accordingly, when the grip 14 is mounted on the barrel 16, the barrel 16 can be smoothly guided to the barrel mounting portion 42.
  • a sandwiching portion 62 is formed at the boundary between the mounting slit 60 and the barrel mounting portion 42.
  • the sandwiching portion 62 is a narrow portion of the mounting slit 60, and the width W1 in the longitudinal direction (arrows Y1 and Y2 directions) in the natural state where the grip 14 is not elastically deformed is larger than the outer diameter of the barrel 16. small.
  • the grip 14 when the grip 14 is mounted on the barrel 16, the barrel 14 elastically deforms by the barrel 16 and the mounting slit 60 is expanded.
  • the sandwiching portion 62 returns to the original width W1 due to the elastic restoring force of the protruding portion 58.
  • the holding portion 62 holds the barrel 16 in the barrel mounting portion 42.
  • the intermediate portion 36 has a flange mounting groove 40 capable of accommodating the flange 24 in a portion near the axis, and an opening direction (arrow X1) substantially perpendicular to the extending direction of the axis a and the pair of finger hooks 30.
  • the flange mounting groove 40 is formed in a groove shape in a portion sandwiched between the front end wall portion 32 and the base end wall portion 34, and communicates with the barrel mounting portion 42 and an insertion hole 44 described later.
  • the flange mounting groove 40 is open at the insertion opening 38, and the flange 24 is inserted from the insertion opening 38. Further, as shown in FIG.
  • the flange mounting groove 40 constitutes a holding groove portion 64 having holding surfaces 64a facing each other in parallel with each other, and an area outside the holding groove portion 64 in the flange mounting groove 40.
  • the outer groove portion 66 has a width that decreases in a taper shape toward the outer side in the protruding direction of 30.
  • the holding groove portion 64 constitutes an inner area of the flange mounting groove 40.
  • the intermediate portion 36 is formed with a through hole 39 that communicates with the flange mounting groove 40 and that faces the insertion opening portion 38 of the intermediate portion 36.
  • a part of the flange 24 enters the through hole 39, so that interference between the flange 24 and the intermediate portion 36 can be prevented.
  • the size of the grip 14 in the lateral direction (X1, X2 directions) can be further reduced.
  • the proximal end wall portion 34 has an insertion hole 44 through which the plunger rod 26 can be inserted, an opening end portion 46 that communicates with the insertion hole 44 and is opened in the opening direction (arrow X1 direction), It is provided with an open end portion 46 and a closed end portion 48 facing each other across the axis a.
  • the insertion hole 44 and the opening end 46 penetrate the axial direction and communicate with the flange mounting groove 40.
  • the insertion hole 44 is formed outside the reference line 54 having a diameter W2 centered on the axis a.
  • the diameter W2 of the reference line 54 is formed to be larger than the diameter of the plunger rod 26 and smaller than the outer diameter of the tip end portion 27 of the plunger rod 26.
  • the insertion hole 44 can insert the plunger rod 26 therethrough.
  • the insertion hole 44 prevents the piston 19 from coming off the barrel 16 by blocking the movement of the distal end portion 27 in the proximal direction.
  • the opening width of the opening end portion 46 has a constant diameter W2 in the opening direction (arrow X1 direction). This allows the plunger rod 26 to be inserted into the insertion hole 44 without resistance when the grip 14 is attached.
  • the closed end 48 is a portion adjacent to the slit direction side (arrow X2 direction side) of the insertion hole 44 and closes the insertion hole 44 on the slit direction side.
  • the closed end 48 includes a central portion 50 located at the center of the grip 14 in the longitudinal direction (arrow Y direction), and a pair of side portions 52 (a pair of lateral portions) that sandwich the central portion 50 from the longitudinal direction (arrow Y direction). ) And.
  • two recesses 56 are formed so as to be cut out so as to protrude from a semicircular reference line 54 having a diameter W2 centered on the axis a. These recesses 56 are cut out so as to extend along the slit direction (arrow X2 direction).
  • the recessed portion 56 of the present embodiment is formed by a triangular notch, and one side thereof coincides with the extension line of the side edge 44 a of the insertion hole 44. Further, the apex 56a of the concave portion 56 on the slit direction side is formed near the side ends of the pair of side portions 52, and the apex 56a projects more toward the slit direction side than the central portion 50. Then, in the closed end portion 48, the outer edges of the recess 56 and the insertion hole 44 are formed so as to draw a substantially M-shaped contour.
  • the two concave portions 56 of the present embodiment are formed so as to project toward the slit direction side with respect to the central portion 50, and are separated from each other in the longitudinal direction of the grip 14, so that the bending stress applied to the closed end portion 48 is prevented. It is configured to be dispersed in the plurality of recesses 56.
  • the constituent material of the grip 14 is not particularly limited, but examples thereof include resin materials such as polypropylene, polycarbonate, polyamide, polysulfone, polyarylate, ABS, and high density polyethylene.
  • the grip 14 is formed by injection molding, for example.
  • the flange 24 of the syringe 12 is inserted and accommodated in the flange mounting groove 40. Further, the barrel 16 is mounted on the barrel mounting portion 42 of the grip 14, and the plunger rod 26 is inserted into the insertion hole 44 of the grip 14. When mounting the barrel 16 on the barrel mounting portion 42, the barrel 16 is inserted along the mounting slit 60 as shown in FIG. 5A.
  • the entire grip 14 is elastically deformed and the width W1 of the holding portion 62 is expanded to the outer diameter of the barrel 16. Therefore, the tip wall portion 32 of the grip 14 is elastically deformed as indicated by an arrow A in the figure, centering on the slit direction side portion of the barrel mounting portion 42.
  • the base end wall portion 34 also elastically deforms around the closed end portion 48 as shown by an arrow B along with the elastic deformation of the tip end wall portion 32.
  • the closed end portion 48 since the diameter of the insertion hole 44 is smaller than the diameter of the barrel mounting portion 42, stress is more likely to be concentrated when elastic deformation as illustrated occurs.
  • a through hole 39 for preventing interference with the flange 24 is formed on the slit direction side of the intermediate portion 36, as the size in the minor axis direction is reduced. .. Therefore, bending stress due to elastic deformation of the grip 14 is more likely to be concentrated on the closed end portion 48 of the base end wall portion 34.
  • the pair of side portions 52 of the closed end portion 48 are provided with two recesses 56 extending in the slit direction (arrow X2 direction) from the reference line 54.
  • bending stress due to elastic deformation of the grip 14 is dispersed in the two recesses 56, and cracking of the closed end 48 can be prevented.
  • the grip 14 of the present embodiment described above has the following effects.
  • the grip 14 of the present embodiment is provided on the central end portion 50, the pair of side portions 52 (a pair of side portions) sandwiching the central portion 50, and the pair of side portions 52 in the base end wall portion 34, and the opening end portion is provided.
  • the two recessed portions 56 are respectively provided at least along the slit direction from the open end portion 46 to the closed end portion 48, or at least along the direction substantially perpendicular to the slit direction. May extend from.
  • the intermediate portion 36 has a through hole 39 that communicates with the flange mounting groove 40 and that faces the insertion opening portion 38 of the intermediate portion 36, and the through hole 39 corresponds to the flange mounting groove 40.
  • a part of the inserted flange 24 can be stored. According to such a grip 14, the size of the grip 14 in the minor axis direction can be reduced, which is preferable.
  • the two recesses 56 extend so that the width of the closed end portion 48 in the slit direction (arrow X2 direction) becomes the widest in the central portion 50.
  • the bending stress can be dispersed in the two recesses 56, so that cracks can be effectively prevented from entering the closed end portion 48.
  • the recess 56 extends so as to draw a substantially M-shape with the two recesses 56 and the outer edge of the insertion hole 44.
  • the bending stress can be dispersed in the two recesses 56, so that cracks can be effectively prevented from entering the closed end portion 48.
  • each of the two recesses 56 extends so as to have a vertex 56a when viewed from the base end direction.
  • the stress is dispersed in the two apexes 56a of the two recesses 56, which is effective in preventing cracks in the closed end 48.
  • the grip 14 may be provided as a syringe system 10A in which the grip 14 is attached to the syringe 12, as shown in FIG. 6, for example.
  • the grip 14 has a syringe 12, a piston 19 slidably inserted into the barrel 16 of the syringe 12, and the piston 19 directed toward the tip direction (arrow Z1 direction).
  • a product is provided as a prefilled syringe 10 in which a plunger rod 26 for pressing and a drug solution M filled in a liquid chamber defined by a barrel 16 and a piston 19 are provided, and a grip 14 is attached to a flange 24 of the syringe 12. May be done.
  • a grip 14A according to the second embodiment of the present invention shown in FIG. 7A has the same shape as the grip 14 (see FIG. 2A) of the first embodiment in the shape of the recess 56A formed in the closed end portion 48 of the base end wall portion 34. Different.
  • the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the closed end 48 of the grip 14A is formed with two recesses 56A spaced apart in the longitudinal direction.
  • the inner end portion 50a (end portion on the X1 direction side) of the central portion 50 of the closed end portion 48 extends in the longitudinal direction (arrow Y1, Y2 direction) of the grip 14A. It is formed in the existing linear shape.
  • Two recesses 56A are formed on a pair of side portions 52 that sandwich the central portion 50 so as to project from a semicircular reference line 54.
  • the recess 56A of the present embodiment has a substantially circular contour, and is cut out so as to extend along the slit direction (arrow X2 direction) and the direction perpendicular to the slit direction (arrow Y1, Y2 direction). Is formed. That is, the recess 56A has a first recess 56A1 extending from the reference line 54 along the slit direction and a second recess 56A2 extending along a direction perpendicular to the slit direction.
  • the end of the recess 56A on the slit direction side protrudes toward the slit direction from the central portion 50, and the end of the recess 56A in the direction perpendicular to the slit direction is larger than the diameter W2 of the insertion hole 44. Also protrudes outward.
  • the grip 14A of this embodiment has the following effects.
  • the grip 14 ⁇ /b>A of the present embodiment in the closed end portion 48, the central portion 50 and the pair of side portions 52 that sandwich the central portion 50, and the slit direction (from the opening end portion 46 toward the closed end portion 48) in the pair of side portions 52 ( There are two recesses 56A extending from the insertion hole 44 along the direction (arrow X2 direction) and the direction perpendicular to the slit direction (directions Y1 and Y2) and distributing the stress on the central portion 50 of the closed end 48.
  • the configuration of the grip 14A of the present embodiment as described above, the bending stress applied to the closed end 48 due to the elastic deformation when the barrel 16 is mounted on the grip 14A is applied to the portion where the two recesses 56A are formed. Can be dispersed in As a result, the concentration of stress on the closed end portion 48 can be prevented and the occurrence of cracks can be prevented.
  • each of the two recesses 56A has a first recess 56A1 extending from the insertion hole 44 along the slit direction and a second recess 56A extending from the insertion hole 44 along a direction perpendicular to the slit direction. And a recess 56A2.
  • the recessed portion 56A spreads over a wider range in the longitudinal direction of the grip 14A, so that the stress related to the closed end portion 48 is also dispersed over a wider range, and the closed end portion is closed. It is suitable for preventing 48 cracks.
  • the recess 56A is formed in a circular contour shape having no apex. As a result, the stress is dispersed in a wider area of the recess 56A, which is suitable for preventing cracks in the closed end 48.
  • a grip 14B according to the third embodiment of the present invention shown in FIG. 8A has the same shape as the grip 14 (see FIG. 2A) of the first embodiment in the shape of the recess 56B formed in the closed end portion 48 of the base end wall portion 34. Different.
  • the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the closed end 48 of the grip 14B is formed with two recesses 56B that are separated in the longitudinal direction (arrow Y1, Y2 directions).
  • the inner end portion 50a of the central portion 50 of the closed end portion 48 is formed in a linear shape extending in the longitudinal direction of the grip 14B.
  • Two recesses 56B are formed on a pair of side portions 52 that sandwich the central portion 50 so as to project from a semicircular reference line 54.
  • the concave portion 56B of the present embodiment has a rectangular contour inclined with respect to the slit direction.
  • the recess 56B has a first recess 56B1 extending from the reference line 54 along the slit direction and a second recess 56B2 extending along a direction perpendicular to the slit direction. At a portion corresponding to a corner of the rectangular contour of the recess 56B, a vertex 56b projecting to the slit direction side from the central portion 50 and a vertex 56c projecting to the outside from the side 44a of the insertion hole 44 are formed. Has been done.
  • the grip 14B of this embodiment has the following effects.
  • each of the two recesses 56B is formed in a rectangular shape inclined with respect to the slit direction, and the portions corresponding to the corners of the rectangular shape project toward the slit direction side with respect to the central portion 50.
  • the apex 56b and the apex 56c protruding outward from the side edge 44a of the insertion hole 44 are formed.
  • the bending stress applied to the closed end 48 of the grip 14B is dispersed in the two recesses 56B. Further, the bending stress acting on the concave portion 56B is further dispersed in the apex 56b and the apex 56c in the concave portion 56B. As a result, it is possible to prevent cracking of the closed end portion 48.
  • a grip 14C according to the fourth embodiment of the present invention shown in FIG. 9A has a shape of a recess 56C formed in the closed end portion 48 of the base end wall portion 34, and is different from the grip 14 of the first embodiment (see FIG. 2A). Different.
  • the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the closed end portion 48 of the grip 14C is formed with two recesses 56C that are separated in the longitudinal direction (arrow Y1, Y2 directions).
  • the inner end portion 48a including the central portion 50 and the pair of side portions 52 of the closed end portion 48 is formed in a straight line along the longitudinal direction of the grip 14C. ..
  • Two recesses 56C extending from a semicircular reference line 54 along a direction perpendicular to the slit direction (directions of arrows Y1 and Y2) are formed in the pair of side portions 52 sandwiching the central portion 50.
  • the recessed portion 56C of the present embodiment is formed in a substantially triangular shape, and one side thereof constitutes the inner end portion 48a of the closed end portion 48.
  • the apex 56d of the recess 56C projects outside the insertion hole 44.
  • the grip 14C of this embodiment has the following effects.
  • the grip 14C of the present embodiment is provided on the central end portion 50, the pair of side portions 52 (a pair of side portions) sandwiching the central portion 50, and the pair of side portions 52 in the base end wall portion 34, and the opening end portion is provided.
  • bending stress due to elastic deformation when the barrel 16 is attached to the grip 14C is dispersed in the two recesses 56C, and cracking of the closed end 48 can be prevented.
  • the width of the closed end portion 48 can be narrowed and the grip 14C can be downsized.

Abstract

A grip (14) including a distal end wall portion (32), a proximal end wall portion (34) facing the distal end wall portion (32), and an intermediate portion (36) coupling the distal end wall portion (32) and the proximal end wall portion (34), wherein a barrel attachment portion (42) attachable to an outer peripheral surface of a barrel (16) is formed in the distal end wall portion (32), a flange attachment groove (40) into which a flange (24) can be inserted is formed in the intermediate portion (36), and an insertion hole (44) into which a plunger rod (26) can be inserted is formed in the proximal end wall portion (34), is provided with two recess portions (56) that extend from the insertion hole (44) and disperse the stress applied to a center (50) of the closed end portion (48), at a pair of side portions (52) of a closed end portion (48) for closing the insertion hole (44) of the proximal end wall portion (34).

Description

グリップ、並びにそれを備えたシリンジシステム及びプレフィルドシリンジGrip, syringe system and prefilled syringe including the same
　本発明は、医療用の注射器のバレルに装着されるグリップ、並びにそれを備えたシリンジシステム及びプレフィルドシリンジに関する。 The present invention relates to a grip attached to a barrel of a medical syringe, a syringe system including the grip, and a prefilled syringe.
　患者への薬液等の投与のために使用される注射器においては、ユーザによる注射器の把持及び操作を容易にするために、注射器の胴部を構成するバレルの基端部に、外方に突出する指掛け部を備えたグリップ（フィンガーグリップ）を装着することが知られている。例えば、国際公開第２０１７／１７０５００号には、バレルの基端部に形成されたフランジに装着されるグリップが開示されている。このグリップには、フランジに装着する際にバレルの外周面に装着するための円形のバレル装着部を備えている。 2. Description of the Related Art In a syringe used for administering a drug solution or the like to a patient, in order to facilitate grasping and operation of the syringe by a user, the syringe is protruded outward at a proximal end of a barrel forming a barrel of the syringe. It is known to attach a grip (finger grip) having a finger hook. For example, WO 2017/170500 discloses a grip attached to a flange formed at the base end of a barrel. The grip is provided with a circular barrel mounting portion for mounting on the outer peripheral surface of the barrel when mounting on the flange.
　ところで、グリップは、バレルに装着された状態から意図せずに外れて落下したりすることが無いように、バレル装着部にはバレルの径よりも狭い幅狭部が形成されており、この幅狭部でバレルを保持するようになっている。このようなグリップをバレルに装着する際には、幅狭部をバレルの径にまで押し広げるようにしてグリップを弾性変形させる。 By the way, the grip has a narrow part that is narrower than the diameter of the barrel so that it does not accidentally come off from the state of being attached to the barrel and fall. Holds the barrel in a narrow space. When mounting such a grip on the barrel, the grip is elastically deformed by widening the narrow portion to the diameter of the barrel.
　ところが、従来のグリップでは、バレルに装着するべくバレル装着部を押し広げる際に、クラックが入るといった問題が生じることがあった。さらに、グリップを小型化するべく、グリップの短手方向の長さを小さくした場合には、より一層クラックが入りやすくなってしまう。 However, with the conventional grip, there was a problem that cracks occurred when expanding the barrel mounting part to mount it on the barrel. Furthermore, if the length of the grip in the short side direction is reduced in order to reduce the size of the grip, cracks are more likely to occur.
　そこで、本実施形態は、バレル装着の際の破損を防ぐことができるグリップ、並びにそれを備えたシリンジシステム及びプレフィルドシリンジを提供することを目的とする。 Therefore, an object of the present embodiment is to provide a grip capable of preventing breakage at the time of barrel mounting, a syringe system including the grip, and a prefilled syringe.
　本発明の一観点は、外方に突出したフランジが基端部に設けられたバレルと、バレルに挿入されたプランジャーロッドと、を備えたシリンジに装着されるグリップであって、先端壁部と、前記先端壁部と対向する基端壁部と、前記先端壁部と前記基端壁部とを連結する中間部と、前記先端壁部から前記基端壁部に向かって延びる中心軸と、を有するベース部と、前記ベース部の側部から前記中心軸と略垂直な方向に、前記中心軸を挟んで互いに反対方向に延びる２つの指掛け部と、を備え、前記中心軸及び前記２つの指掛け部の延長方向と略垂直な開口方向に開口した挿入開口部を有し、かつ、前記先端壁部と前記基端壁部とに挟まれた、前記フランジを挿入可能なフランジ装着溝を、前記中間部は備え、前記先端壁部は、前記先端壁部を前記中心軸に沿って貫通し、前記フランジ装着溝と連通し、かつ、前記開口方向に開口した、前記バレルの外周面に装着可能なバレル装着部を有し、前記基端壁部は、前記基端壁部を前記中心軸に沿って貫通し、前記フランジ装着溝と連通した、前記プランジャーロッドを挿通可能な挿通孔と、前記挿通孔と連通し、前記開口方向に開口した開口端部と、前記開口端部と前記中心軸を挟んで対向する閉塞端部と、を有し、前記閉塞端部は、中央部と、前記中央部を挟み、前記２つの指掛け部の各々と連結した一対の側部と、前記一対の側部のそれぞれに形成された２つの凹部と、を有し、前記２つの凹部はそれぞれ、前記閉塞端部の前記中央部にかかる応力を分散するように、前記中心軸から離間する方向に、前記挿通孔から延びている、グリップにある。 One aspect of the present invention is a grip mounted on a syringe including a barrel having an outwardly projecting flange provided at a base end portion thereof, and a plunger rod inserted into the barrel, the tip wall portion being a grip. A proximal end wall portion facing the distal end wall portion, an intermediate portion connecting the distal end wall portion and the proximal end wall portion, and a central axis extending from the distal end wall portion toward the proximal end wall portion. , And two finger hooks extending from the side of the base portion in a direction substantially perpendicular to the central axis in directions opposite to each other with the central axis interposed therebetween. A flange mounting groove that has an insertion opening that opens in an opening direction that is substantially perpendicular to the extension direction of the two finger hooks, and that is sandwiched between the tip wall portion and the base end wall portion and into which the flange can be inserted. , The intermediate portion is provided, and the tip wall portion penetrates the tip wall portion along the central axis, communicates with the flange mounting groove, and is opened in the opening direction on an outer peripheral surface of the barrel. A barrel mounting portion that can be mounted, and the base end wall portion penetrates the base end wall portion along the central axis and is in communication with the flange mounting groove, and is an insertion hole through which the plunger rod can be inserted. And an opening end communicating with the insertion hole and opening in the opening direction, and a closing end facing the opening end with the central axis interposed therebetween, and the closing end has a central portion. And a pair of side portions sandwiching the central portion and connected to each of the two finger-holding portions, and two concave portions formed in each of the pair of side portions, and the two concave portions are respectively formed. The grip extends from the insertion hole in the direction away from the central axis so as to disperse the stress applied to the central portion of the closed end.
　また、本発明の別の一観点は、上記観点のグリップと、シリンジと、を備えたシリンジシステムにある。 Another aspect of the present invention is a syringe system including the grip of the above aspect and a syringe.
　本発明のさらに別の一観点は、上記観点のグリップと、基端部にフランジが形成されたシリンジと、前記シリンジのバレル内に摺動可能に挿入されたピストンと、前記ピストンを先端方向に向かって押圧するための前記プランジャーロッドと、前記バレルと前記ピストンとで画成される液室内に充填された薬液と、を備え、前記グリップが前記シリンジの前記フランジに装着されている、プレフィルドシリンジにある。 Yet another aspect of the present invention is a grip of the above viewpoint, a syringe having a flange formed at the base end, a piston slidably inserted into the barrel of the syringe, and the piston in the distal direction. Prefilled, comprising: the plunger rod for pressing toward and a liquid medicine filled in a liquid chamber defined by the barrel and the piston, wherein the grip is attached to the flange of the syringe. It's in a syringe.
　上記観点のグリップ、並びにそれを備えたシリンジシステム及びプレフィルドシリンジによれば、プランジャーロッドを通す挿通孔において、閉塞端部の中央部にかかる応力を分散する２つの凹部を設けた。これにより、グリップをシリンジに装着する際に、割れやクラックの発生を防ぐことができる。 According to the grip from the above viewpoint, and the syringe system and the prefilled syringe equipped with the grip, two recesses are provided in the insertion hole through which the plunger rod is inserted, which distributes the stress applied to the central portion of the closed end. As a result, it is possible to prevent the occurrence of cracks and cracks when the grip is attached to the syringe.
第１実施形態のプレフィルドシリンジの斜視図である。It is a perspective view of the prefilled syringe of 1st Embodiment. 図２Ａは、第１実施形態に係るグリップの斜視図であり、図２Ｂは図２Ａのグリップを基端側から見て示す平面図である。2A is a perspective view of the grip according to the first embodiment, and FIG. 2B is a plan view showing the grip of FIG. 2A as viewed from the base end side. 図３Ａは、図２Ａのグリップを先端側から見て示す底面図であり、図３Ｂは図３ＡのＩＩＩＢ－ＩＩＩＢ線に沿った断面図である。3A is a bottom view showing the grip of FIG. 2A as seen from the tip side, and FIG. 3B is a sectional view taken along line IIIB-IIIB of FIG. 3A. 図１のシリンジの断面図である。It is sectional drawing of the syringe of FIG. 図５Ａは、シリンジ装着時の先端壁部の変形状態を示す断面図であり、図５Ｂはシリンジ装着時の基端壁部の変形状態を示す断面図である。FIG. 5A is a sectional view showing a deformed state of the distal end wall portion when the syringe is mounted, and FIG. 5B is a sectional view showing a deformed state of the proximal end wall portion when the syringe is mounted. 第１実施形態に係るグリップを装着したシリンジシステムの斜視図である。It is a perspective view of a syringe system equipped with a grip according to the first embodiment. 図７Ａは、第２実施形態に係るグリップの斜視図であり、図７Ｂは図７Ａのグリップを基端側から見て示す平面図である。7A is a perspective view of the grip according to the second embodiment, and FIG. 7B is a plan view showing the grip of FIG. 7A as seen from the base end side. 図８Ａは、第３実施形態に係るグリップの斜視図であり、図８Ｂは図８Ａのグリップを基端側から見て示す平面図である。FIG. 8A is a perspective view of a grip according to the third embodiment, and FIG. 8B is a plan view showing the grip of FIG. 8A as seen from the base end side. 図９Ａは、第４実施形態に係るグリップの斜視図であり、図９Ｂは図９Ａのグリップを基端側から見て示す平面図である。9A is a perspective view of the grip according to the fourth embodiment, and FIG. 9B is a plan view showing the grip of FIG. 9A as viewed from the base end side.
　以下、本発明の好適な実施形態を挙げ、添付の図面を参照して詳細に説明する。なお、図面の寸法比率は、説明の都合上、誇張されて実際の比率とは異なる場合がある。また、以下の説明において、プレフィルドシリンジ（又はシリンジシステム）を構成する各部材において、針先側の端部を「先端」とよび、その反対の方向の端部を「基端」と呼ぶ。 Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. Note that the dimensional ratios in the drawings may be exaggerated and different from the actual ratios for convenience of description. Further, in the following description, in each member constituting the prefilled syringe (or syringe system), the end on the needle tip side is called a “tip”, and the end in the opposite direction is called a “base end”.
（第１実施形態）
　図１において、本実施形態に係るプレフィルドシリンジ１０は、シリンジ１２と、シリンジ１２に装着されたグリップ１４とを備える。プレフィルドシリンジ１０は、シリンジ１２に薬液Ｍが予め充填された状態で製品として提供される。 (First embodiment)
In FIG. 1, the prefilled syringe 10 according to the present embodiment includes a syringe 12 and a grip 14 attached to the syringe 12. The prefilled syringe 10 is provided as a product in a state in which the syringe 12 is prefilled with the drug solution M.
　シリンジ１２は、シリンジ１２の胴部を構成する中空状のバレル１６と、バレル１６内に充填された薬液Ｍと、バレル１６内に挿入されたガスケット１８と、バレル１６の先端に設けられた針保持部２０と、針保持部２０に装着されたキャップ２２とを備える。シリンジ１２は、使用時にキャップ２２をはずして不図示の穿刺針を針保持部２０に装着して、注射装置に組み上げられる。 The syringe 12 includes a hollow barrel 16 that forms the body of the syringe 12, a drug solution M filled in the barrel 16, a gasket 18 inserted in the barrel 16, and a needle provided at the tip of the barrel 16. The holding unit 20 and the cap 22 attached to the needle holding unit 20 are provided. When the syringe 12 is used, the cap 22 is removed and a puncture needle (not shown) is attached to the needle holding portion 20 to be assembled into an injection device.
　バレル１６は、略円筒形状を為すとともに、基端に基端開口部１７を有する中空体である。バレル１６の基端外周部には、フランジ２４が径方向外方に向かって突出形成されている。バレル１６内には、基端開口部１７を介してガスケット１８が挿入されている。ガスケット１８によってバレル１６の基端側が液密に封止され、薬液Ｍがバレル１６内に封入されている。 The barrel 16 is a hollow body having a substantially cylindrical shape and having a base end opening 17 at the base end. A flange 24 is formed on the outer peripheral portion of the base end of the barrel 16 so as to project radially outward. A gasket 18 is inserted into the barrel 16 via a base end opening 17. The base end side of the barrel 16 is liquid-tightly sealed by the gasket 18, and the chemical liquid M is sealed in the barrel 16.
　ガスケット１８は、例えば、ゴム材等の弾性材料により構成されている。ガスケット１８は、その外周部がバレル１６の内周面に液密に接するとともに、バレル１６内に摺動可能に配置されている。ガスケット１８には、プランジャーロッド２６の先端部２７が連結されている。ガスケット１８及び先端部２７によりピストン１９が構成される。ユーザがプランジャーロッド２６を先端方向に押圧することにより、ガスケット１８がバレル１６内を先端方向に摺動する。なお、プランジャーロッド２６は、シリンジ１２に穿刺針（不図示）を装着して薬液Ｍを患者に投与するときにガスケット１８に連結されてもよい。 The gasket 18 is made of, for example, an elastic material such as a rubber material. The outer periphery of the gasket 18 is in liquid-tight contact with the inner peripheral surface of the barrel 16 and is slidably arranged in the barrel 16. The distal end portion 27 of the plunger rod 26 is connected to the gasket 18. The gasket 18 and the tip portion 27 form a piston 19. When the user pushes the plunger rod 26 in the distal direction, the gasket 18 slides in the barrel 16 in the distal direction. The plunger rod 26 may be connected to the gasket 18 when a puncture needle (not shown) is attached to the syringe 12 to administer the drug solution M to the patient.
　針保持部２０は、バレル１６の先端部に一体的に形成されている。図６に示すように、バレル１６の先端中央部からバレル１６に対して縮径して先端方向（Ｚ１方向）に延出したノズル２０ａと、ノズル２０ａの外周部を囲むように形成された雌ねじ部２０ｂとを備える。輸送及び保管の際には、図１に示すようにキャップ２２が針保持部２０の雌ねじに装着されている。使用時には、キャップ２２が取り外され、針保持部２０に穿刺針（不図示）が装着される。 The needle holder 20 is formed integrally with the tip of the barrel 16. As shown in FIG. 6, the nozzle 20a extending from the center of the tip of the barrel 16 toward the tip of the barrel 16 in the tip direction (Z1 direction) and the female screw formed so as to surround the outer periphery of the nozzle 20a. And a section 20b. At the time of transportation and storage, the cap 22 is attached to the female screw of the needle holding portion 20 as shown in FIG. At the time of use, the cap 22 is removed and a puncture needle (not shown) is attached to the needle holder 20.
　次に、グリップ１４の構成について説明する。図１のように、グリップ１４は、プレフィルドシリンジ１０の製品提供状態において、バレル１６の基端外周部に装着されている。なお、プレフィルドシリンジ１０の製品提供状態において、グリップ１４は、シリンジ１２から分離しており、ユーザが使用する際にバレル１６の基端外周部に装着されてもよい。以下、グリップ１４に関し、図２Ａの中心軸線ａを単に「軸線ａ」といい、軸線ａの延在方向を「軸方向」という。なお、グリップ１４の軸線ａはグリップ１４をシリンジ１２に装着した際に、シリンジ１２の中心軸と同一直線上に位置する。 Next, the structure of the grip 14 will be described. As shown in FIG. 1, the grip 14 is attached to the outer peripheral portion of the base end of the barrel 16 in the product providing state of the prefilled syringe 10. It should be noted that in the product providing state of the prefilled syringe 10, the grip 14 may be separated from the syringe 12 and attached to the outer peripheral portion of the proximal end of the barrel 16 when used by the user. Hereinafter, regarding the grip 14, the central axis a in FIG. 2A is simply referred to as “axis a”, and the extending direction of the axis a is referred to as “axial direction”. The axis a of the grip 14 is located on the same straight line as the central axis of the syringe 12 when the grip 14 is attached to the syringe 12.
　図２Ａに示すように、グリップ１４は、プランジャーロッド２６を挿通可能に構成されている。具体的に、グリップ１４は、一対の指掛け部３０を有するベース部３１を有している。 As shown in FIG. 2A, the grip 14 is configured so that the plunger rod 26 can be inserted therethrough. Specifically, the grip 14 has a base portion 31 having a pair of finger hooks 30.
　ベース部３１は、グリップ１４の軸方向中央部を構成する部分であって、グリップ１４の軸線ａに直交する板状に形成されている。したがって、ベース部３１は、グリップ１４の軸方向に厚さを有する。ベース部３１における一対の指掛け部３０は、軸線ａに直交して互いに反対方向に突出している。これにより、図２Ｂに示すように、軸方向から見たベース部３１の形状は、指掛け部３０の突出方向に相対的に長尺であり、当該突出方向に直交する方向に短尺に形成されている。図１に示すように、グリップ１４がバレル１６に装着された状態において、一対の指掛け部３０は、フランジ２４よりも外方に突出する。 The base portion 31 is a portion that constitutes the central portion of the grip 14 in the axial direction, and is formed in a plate shape orthogonal to the axis a of the grip 14. Therefore, the base portion 31 has a thickness in the axial direction of the grip 14. The pair of finger hooks 30 of the base portion 31 are orthogonal to the axis a and project in opposite directions. As a result, as shown in FIG. 2B, the shape of the base portion 31 as viewed from the axial direction is relatively long in the protruding direction of the finger hanging portion 30 and short in the direction orthogonal to the protruding direction. There is. As shown in FIG. 1, in the state where the grip 14 is mounted on the barrel 16, the pair of finger hooks 30 project outward from the flange 24.
　ベース部３１は、先端側に形成される板状の先端壁部３２と、先端壁部３２の基端側に対向配置された基端壁部３４と、先端壁部３２と基端壁部３４とを連結する中間部３６とを備えている。中間部３６には、フランジ２４が挿入可能なフランジ装着溝４０が形成されている。 The base portion 31 includes a plate-shaped tip end wall portion 32 formed on the tip end side, a base end wall portion 34 arranged to face the base end side of the tip end wall portion 32, a tip end wall portion 32, and a base end wall portion 34. And an intermediate portion 36 that connects the and. A flange mounting groove 40 into which the flange 24 can be inserted is formed in the intermediate portion 36.
　先端壁部３２には、先端側（Ｚ１方向）に突出した突出部５８と、バレル１６の外周面に装着可能なバレル装着部４２と、が形成されている。突出部５８は、軸線ａを中心に周方向に円弧状に延在するように形成されている。すなわち、突出部５８は、円形リング状の一部が切り欠かれた形状（断面Ｃ字状）に形成されている。突出部５８において切り欠かれた部分は、装着用スリット６０の一部を構成し、先端壁部３２の短尺方向一方側（「開口側」又は「Ｘ１方向側」ともいう）に延在する。 The tip wall portion 32 is formed with a protrusion 58 protruding toward the tip side (Z1 direction) and a barrel mounting portion 42 that can be mounted on the outer peripheral surface of the barrel 16. The protrusion 58 is formed so as to extend in an arc shape in the circumferential direction around the axis a. That is, the protruding portion 58 is formed in a shape (C-shaped cross section) in which a circular ring shape is partially cut out. The cutout portion of the protrusion 58 forms a part of the mounting slit 60 and extends to one side (also referred to as “opening side” or “X1 direction side”) of the distal end wall portion 32 in the short direction.
　バレル装着部４２は、突出部５８の内周側によって構成されており、先端壁部３２を軸方向に貫通してフランジ装着溝４０に連通している。バレル装着部４２は、バレル１６（図１参照）の外周面に装着可能とするべく、バレル１６の外径と同じ内径又はこれに近い内径の円周面として形成されている。また、バレル装着部４２は、装着用スリット６０を介して開口側（Ｘ１方向側）に開口している。 The barrel mounting portion 42 is configured by the inner peripheral side of the protruding portion 58, and penetrates the tip wall portion 32 in the axial direction to communicate with the flange mounting groove 40. The barrel mounting portion 42 is formed as a circumferential surface having an inner diameter equal to or close to the outer diameter of the barrel 16 so that the barrel mounting portion 42 can be mounted on the outer peripheral surface of the barrel 16 (see FIG. 1 ). Further, the barrel mounting portion 42 is open to the opening side (X1 direction side) via the mounting slit 60.
　図３Ａに示すように、装着用スリット６０は、バレル装着部４２とグリップ１４の外部とを連通し、先端壁部３２を軸方向に縦断する隙間である。装着用スリット６０の開口幅は、先端壁部３２の開口方向（Ｘ１方向）に向かって増大している。これにより、グリップ１４をバレル１６に装着する際、バレル装着部４２へとバレル１６をスムーズに案内することができる。 As shown in FIG. 3A, the mounting slit 60 is a gap that connects the barrel mounting portion 42 and the outside of the grip 14 and vertically cuts the tip wall portion 32 in the axial direction. The opening width of the mounting slit 60 increases in the opening direction (X1 direction) of the distal end wall portion 32. Accordingly, when the grip 14 is mounted on the barrel 16, the barrel 16 can be smoothly guided to the barrel mounting portion 42.
　また、装着用スリット６０とバレル装着部４２との境界部分には、挟持部６２が形成されている。挟持部６２は、装着用スリット６０の幅狭部であり、グリップ１４が弾性変形していない自然状態での長尺方向（矢印Ｙ１、Ｙ２方向）の幅Ｗ１が、バレル１６の外径よりも小さい。これにより、グリップ１４をバレル１６に装着する際、バレル１６によって、グリップ１４が弾性変形し、装着用スリット６０が押し広げられる。バレル１６がバレル装着部４２内に収容されると、突出部５８の弾性復元力によって挟持部６２が元の幅Ｗ１に戻る。この挟持部６２により、バレル１６がバレル装着部４２内に保持される。 A sandwiching portion 62 is formed at the boundary between the mounting slit 60 and the barrel mounting portion 42. The sandwiching portion 62 is a narrow portion of the mounting slit 60, and the width W1 in the longitudinal direction (arrows Y1 and Y2 directions) in the natural state where the grip 14 is not elastically deformed is larger than the outer diameter of the barrel 16. small. As a result, when the grip 14 is mounted on the barrel 16, the barrel 14 elastically deforms by the barrel 16 and the mounting slit 60 is expanded. When the barrel 16 is housed in the barrel mounting portion 42, the sandwiching portion 62 returns to the original width W1 due to the elastic restoring force of the protruding portion 58. The holding portion 62 holds the barrel 16 in the barrel mounting portion 42.
　図２Ａに示すように、中間部３６は、軸寄りの部分にフランジ２４を収容可能なフランジ装着溝４０と、軸線ａ及び一対の指掛け部３０の延在方向と略垂直な開口方向（矢印Ｘ１方向）に開口した挿入開口部３８と、を備える。フランジ装着溝４０は、先端壁部３２と基端壁部３４とに挟まれた部分に溝状に形成されており、バレル装着部４２及び後述する挿通孔４４と連通している。フランジ装着溝４０は、挿入開口部３８において開口しており、その挿入開口部３８からフランジ２４が挿入される。また、図３Ｂに示すように、フランジ装着溝４０は、互いに平行に対向する保持面６４ａを有する保持溝部６４と、フランジ装着溝４０における保持溝部６４よりも外側領域を構成し、一対の指掛け部３０の突出方向外側に向かってテーパ状に幅が減少する外側溝部６６と、を有する。 As shown in FIG. 2A, the intermediate portion 36 has a flange mounting groove 40 capable of accommodating the flange 24 in a portion near the axis, and an opening direction (arrow X1) substantially perpendicular to the extending direction of the axis a and the pair of finger hooks 30. Direction). The flange mounting groove 40 is formed in a groove shape in a portion sandwiched between the front end wall portion 32 and the base end wall portion 34, and communicates with the barrel mounting portion 42 and an insertion hole 44 described later. The flange mounting groove 40 is open at the insertion opening 38, and the flange 24 is inserted from the insertion opening 38. Further, as shown in FIG. 3B, the flange mounting groove 40 constitutes a holding groove portion 64 having holding surfaces 64a facing each other in parallel with each other, and an area outside the holding groove portion 64 in the flange mounting groove 40. The outer groove portion 66 has a width that decreases in a taper shape toward the outer side in the protruding direction of 30.
　保持溝部６４は、フランジ装着溝４０における内側領域を構成している。グリップ１４がバレル１６に装着された状態では、図４に示すように、保持溝部６４にフランジ２４が挿入され、互いに対向する保持面６４ａにより挟まれたフランジ２４が保持される。これにより、バレル１６に対するグリップ１４の軸方向の相対移動が規制される。 The holding groove portion 64 constitutes an inner area of the flange mounting groove 40. When the grip 14 is attached to the barrel 16, as shown in FIG. 4, the flange 24 is inserted into the holding groove portion 64, and the flange 24 sandwiched by the holding surfaces 64a facing each other is held. As a result, the relative movement of the grip 14 in the axial direction with respect to the barrel 16 is restricted.
　また、図３Ｂに示すように、中間部３６には、フランジ装着溝４０と連通し、かつ、中間部３６の挿入開口部３８と対向する貫通孔３９が形成されている。フランジ２４をフランジ装着溝４０に挿入した際に、フランジ２４の一部が貫通孔３９に入ることで、フランジ２４と中間部３６との干渉を防ぐことができる。これにより、グリップ１４の短手方向（Ｘ１、Ｘ２方向）のサイズをさらに小型化することができる。 Further, as shown in FIG. 3B, the intermediate portion 36 is formed with a through hole 39 that communicates with the flange mounting groove 40 and that faces the insertion opening portion 38 of the intermediate portion 36. When the flange 24 is inserted into the flange mounting groove 40, a part of the flange 24 enters the through hole 39, so that interference between the flange 24 and the intermediate portion 36 can be prevented. As a result, the size of the grip 14 in the lateral direction (X1, X2 directions) can be further reduced.
　図２Ｂに示すように、基端壁部３４は、プランジャーロッド２６を挿通可能な挿通孔４４と、挿通孔４４と連通して開口方向（矢印Ｘ１方向）に開口した開口端部４６と、開口端部４６と軸線ａを挟んで対向する閉塞端部４８とを備えている。挿通孔４４及び開口端部４６は、軸方向に貫通してフランジ装着溝４０に連通している。挿通孔４４は、軸線ａを中心にした直径Ｗ２の基準ライン５４の外側に形成されている。基準ライン５４の直径Ｗ２は、プランジャーロッド２６の径よりも大きく、かつプランジャーロッド２６の先端部２７の外径よりも小さく形成されている。これにより、挿通孔４４は、プランジャーロッド２６を挿通させることができる。また、挿通孔４４は、先端部２７の基端方向への移動を阻止することで、ピストン１９がバレル１６から抜け止めとなる。 As shown in FIG. 2B, the proximal end wall portion 34 has an insertion hole 44 through which the plunger rod 26 can be inserted, an opening end portion 46 that communicates with the insertion hole 44 and is opened in the opening direction (arrow X1 direction), It is provided with an open end portion 46 and a closed end portion 48 facing each other across the axis a. The insertion hole 44 and the opening end 46 penetrate the axial direction and communicate with the flange mounting groove 40. The insertion hole 44 is formed outside the reference line 54 having a diameter W2 centered on the axis a. The diameter W2 of the reference line 54 is formed to be larger than the diameter of the plunger rod 26 and smaller than the outer diameter of the tip end portion 27 of the plunger rod 26. Thereby, the insertion hole 44 can insert the plunger rod 26 therethrough. Further, the insertion hole 44 prevents the piston 19 from coming off the barrel 16 by blocking the movement of the distal end portion 27 in the proximal direction.
　開口端部４６の開口幅は、開口方向（矢印Ｘ１方向）に一定の直径Ｗ２となっている。これにより、グリップ１４を装着する際に、プランジャーロッド２６を抵抗なく挿通孔４４に挿入することができる。 The opening width of the opening end portion 46 has a constant diameter W2 in the opening direction (arrow X1 direction). This allows the plunger rod 26 to be inserted into the insertion hole 44 without resistance when the grip 14 is attached.
　閉塞端部４８は、挿通孔４４のスリット方向側（矢印Ｘ２方向側）に隣接した部分であり、挿通孔４４のスリット方向側を閉塞している。閉塞端部４８は、グリップ１４の長手方向（矢印Ｙ方向）の中央に位置する中央部５０と、その中央部５０を長手方向（矢印Ｙ方向）から挟む一対の側部５２（一対の側部）とを備える。その一対の側部５２には、軸線ａを中心とする直径Ｗ２の半円形の基準ライン５４から、はみ出すように切り欠かれてなる２つの凹部５６が形成されている。これらの凹部５６は、スリット方向（矢印Ｘ２方向）に沿って延び出るように切り欠かれている。本実施形態の凹部５６は、三角形状の切欠きよりなり、その一辺は挿通孔４４の側辺４４ａの延長線と一致している。また、凹部５６のスリット方向側の頂点５６ａは一対の側部５２の側端付近に形成されており、かつ、その頂点５６ａは、中央部５０よりもスリット方向側に突出している。そして、閉塞端部４８において凹部５６及び挿通孔４４の外縁が略Ｍ字型の輪郭を描くように形成されている。このように、本実施形態の２つの凹部５６は、中央部５０よりもスリット方向側に突出して形成されるとともに、グリップ１４の長手方向に離間されており、閉塞端部４８に加わる曲げ応力を複数の凹部５６に分散できるように構成されている。 The closed end 48 is a portion adjacent to the slit direction side (arrow X2 direction side) of the insertion hole 44 and closes the insertion hole 44 on the slit direction side. The closed end 48 includes a central portion 50 located at the center of the grip 14 in the longitudinal direction (arrow Y direction), and a pair of side portions 52 (a pair of lateral portions) that sandwich the central portion 50 from the longitudinal direction (arrow Y direction). ) And. In the pair of side portions 52, two recesses 56 are formed so as to be cut out so as to protrude from a semicircular reference line 54 having a diameter W2 centered on the axis a. These recesses 56 are cut out so as to extend along the slit direction (arrow X2 direction). The recessed portion 56 of the present embodiment is formed by a triangular notch, and one side thereof coincides with the extension line of the side edge 44 a of the insertion hole 44. Further, the apex 56a of the concave portion 56 on the slit direction side is formed near the side ends of the pair of side portions 52, and the apex 56a projects more toward the slit direction side than the central portion 50. Then, in the closed end portion 48, the outer edges of the recess 56 and the insertion hole 44 are formed so as to draw a substantially M-shaped contour. As described above, the two concave portions 56 of the present embodiment are formed so as to project toward the slit direction side with respect to the central portion 50, and are separated from each other in the longitudinal direction of the grip 14, so that the bending stress applied to the closed end portion 48 is prevented. It is configured to be dispersed in the plurality of recesses 56.
　グリップ１４の構成材料は特に限定されないが、例えば、ポリプロピレン、ポリカーボネート、ポリアミド、ポリサルフォン、ポリアリレート、ＡＢＳ、高密度ポリエチレン等の樹脂材料が挙げられる。グリップ１４は、例えば、射出成型により形成される。 The constituent material of the grip 14 is not particularly limited, but examples thereof include resin materials such as polypropylene, polycarbonate, polyamide, polysulfone, polyarylate, ABS, and high density polyethylene. The grip 14 is formed by injection molding, for example.
　次に、上記のように構成されたグリップ１４の作用及び効果について説明する。 Next, the operation and effect of the grip 14 configured as above will be described.
　図４に示すように、グリップ１４の使用状態において、フランジ装着溝４０には、シリンジ１２のフランジ２４が挿入され収容される。また、グリップ１４のバレル装着部４２には、バレル１６が装着され、グリップ１４の挿通孔４４にはプランジャーロッド２６が挿入される。バレル装着部４２にバレル１６を装着する際には、図５Ａに示すように、装着用スリット６０に沿ってバレル１６が挿入される。 As shown in FIG. 4, when the grip 14 is in use, the flange 24 of the syringe 12 is inserted and accommodated in the flange mounting groove 40. Further, the barrel 16 is mounted on the barrel mounting portion 42 of the grip 14, and the plunger rod 26 is inserted into the insertion hole 44 of the grip 14. When mounting the barrel 16 on the barrel mounting portion 42, the barrel 16 is inserted along the mounting slit 60 as shown in FIG. 5A.
　図示のように、バレル１６が装着用スリット６０の挟持部６２を通過する際には、グリップ１４全体が弾性変形して挟持部６２の幅Ｗ１がバレル１６の外径まで押し広げられる。そのため、グリップ１４の先端壁部３２では、バレル装着部４２のスリット方向側の部分を中心にして図中の矢印Ａに示すように弾性変形する。 As shown in the figure, when the barrel 16 passes through the holding portion 62 of the mounting slit 60, the entire grip 14 is elastically deformed and the width W1 of the holding portion 62 is expanded to the outer diameter of the barrel 16. Therefore, the tip wall portion 32 of the grip 14 is elastically deformed as indicated by an arrow A in the figure, centering on the slit direction side portion of the barrel mounting portion 42.
　図５Ｂに示すように、基端壁部３４も先端壁部３２の弾性変形に伴って、矢印Ｂに示すように、閉塞端部４８を中心に弾性変形する。ここで、閉塞端部４８は、挿通孔４４の径がバレル装着部４２の径よりも小さいことから、図示のような弾性変形が発生した際に応力がより集中しやすい。また、本実施形態のグリップ１４においては、短径方向のサイズを小型化したことに伴って、中間部３６のスリット方向側にフランジ２４との干渉を防ぐための貫通孔３９が形成されている。そのため、グリップ１４の弾性変形による曲げ応力が基端壁部３４の閉塞端部４８により一層集中しやすくなっている。 As shown in FIG. 5B, the base end wall portion 34 also elastically deforms around the closed end portion 48 as shown by an arrow B along with the elastic deformation of the tip end wall portion 32. Here, in the closed end portion 48, since the diameter of the insertion hole 44 is smaller than the diameter of the barrel mounting portion 42, stress is more likely to be concentrated when elastic deformation as illustrated occurs. In addition, in the grip 14 of the present embodiment, a through hole 39 for preventing interference with the flange 24 is formed on the slit direction side of the intermediate portion 36, as the size in the minor axis direction is reduced. .. Therefore, bending stress due to elastic deformation of the grip 14 is more likely to be concentrated on the closed end portion 48 of the base end wall portion 34.
　したがって、挿通孔４４を基準ライン５４に沿った形状とした場合には、閉塞端部４８の幅が狭くなった中央部５０の一カ所に応力が集中してしまい、中央部５０にクラックが生じやすい。 Therefore, when the insertion hole 44 has a shape along the reference line 54, stress concentrates at one place of the central portion 50 where the width of the closed end portion 48 is narrowed, and a crack occurs in the central portion 50. Cheap.
　これに対し、本実施形態のグリップ１４では、閉塞端部４８の一対の側部５２において、基準ライン５４よりもスリット方向（矢印Ｘ２方向）に延び出た２つの凹部５６を設けている。これにより、グリップ１４の弾性変形による曲げ応力が２つの凹部５６に分散され、閉塞端部４８のクラック発生を防止できる。 On the other hand, in the grip 14 of the present embodiment, the pair of side portions 52 of the closed end portion 48 are provided with two recesses 56 extending in the slit direction (arrow X2 direction) from the reference line 54. As a result, bending stress due to elastic deformation of the grip 14 is dispersed in the two recesses 56, and cracking of the closed end 48 can be prevented.
　以上に説明した本実施形態のグリップ１４は、以下の効果を奏する。 The grip 14 of the present embodiment described above has the following effects.
　本実施形態のグリップ１４は、基端壁部３４において、中央部５０と、中央部５０を挟む一対の側部５２（一対の側部）と、一対の側部５２に設けられ、開口端部４６から閉塞端部４８に向かうスリット方向（矢印Ｘ２方向）に沿って挿通孔４４から延び、閉塞端部４８の中央部５０にかかる応力を分散する２つの凹部５６を有する。これにより、グリップ１４にバレル１６を装着する際の弾性変形による曲げ応力が２つの凹部５６に分散され、閉塞端部４８のクラック発生を防止できる。また、閉塞端部４８にクラックが発生しにくくなるため、閉塞端部４８の幅を狭くすることができ、グリップ１４を小型化することができる。 The grip 14 of the present embodiment is provided on the central end portion 50, the pair of side portions 52 (a pair of side portions) sandwiching the central portion 50, and the pair of side portions 52 in the base end wall portion 34, and the opening end portion is provided. There are two recesses 56 extending from the insertion hole 44 along the slit direction (direction of arrow X2) extending from 46 to the closed end 48 and distributing stress applied to the central portion 50 of the closed end 48. As a result, bending stress due to elastic deformation when the barrel 16 is mounted on the grip 14 is dispersed in the two recesses 56, and cracking of the closed end 48 can be prevented. Further, since cracks are less likely to occur in the closed end portion 48, the width of the closed end portion 48 can be narrowed and the grip 14 can be downsized.
　本実施形態のグリップ１４において、２つの凹部５６はそれぞれ、少なくとも開口端部４６から閉塞端部４８に向かうスリット方向に沿って、又は、少なくともスリット方向と略垂直な方向に沿って、挿通孔４４から延びていてもよい。 In the grip 14 of the present embodiment, the two recessed portions 56 are respectively provided at least along the slit direction from the open end portion 46 to the closed end portion 48, or at least along the direction substantially perpendicular to the slit direction. May extend from.
　本実施形態のグリップ１４において、中間部３６は、フランジ装着溝４０と連通し、かつ、中間部３６の挿入開口部３８と対向する貫通孔３９を有し、貫通孔３９はフランジ装着溝４０に挿入されたフランジ２４の一部を収納可能に構成されている。このようなグリップ１４によれば、グリップ１４の短径方向のサイズを小型化できて好適である。 In the grip 14 of the present embodiment, the intermediate portion 36 has a through hole 39 that communicates with the flange mounting groove 40 and that faces the insertion opening portion 38 of the intermediate portion 36, and the through hole 39 corresponds to the flange mounting groove 40. A part of the inserted flange 24 can be stored. According to such a grip 14, the size of the grip 14 in the minor axis direction can be reduced, which is preferable.
　本実施形態のグリップ１４において、閉塞端部４８のスリット方向（矢印Ｘ２方向）の幅が中央部５０において最も広くなるように２つの凹部５６が延びている。これにより、２つの凹部５６に曲げ応力を分散させることができるので、閉塞端部４８にクラックが入るのを効果的に防止できる。 In the grip 14 of the present embodiment, the two recesses 56 extend so that the width of the closed end portion 48 in the slit direction (arrow X2 direction) becomes the widest in the central portion 50. As a result, the bending stress can be dispersed in the two recesses 56, so that cracks can be effectively prevented from entering the closed end portion 48.
　本実施形態のグリップ１４において、２つの凹部５６及び挿通孔４４の外縁とで略Ｍ字型を描くように凹部５６が延びている。これにより、２つの凹部５６に曲げ応力を分散させることができるので、閉塞端部４８にクラックが入るのを効果的に防止できる。 In the grip 14 of the present embodiment, the recess 56 extends so as to draw a substantially M-shape with the two recesses 56 and the outer edge of the insertion hole 44. As a result, the bending stress can be dispersed in the two recesses 56, so that cracks can be effectively prevented from entering the closed end portion 48.
　本実施形態のグリップ１４において、２つの凹部５６の各々は、基端方向から見るときに頂点５６ａを有するように延びている。これにより、２つの凹部５６の２つの頂点５６ａの部分に応力が分散されるので、閉塞端部４８のクラック防止に効果的である。 In the grip 14 of the present embodiment, each of the two recesses 56 extends so as to have a vertex 56a when viewed from the base end direction. As a result, the stress is dispersed in the two apexes 56a of the two recesses 56, which is effective in preventing cracks in the closed end 48.
　上記のグリップ１４は、例えば、図６に示すように、シリンジ１２にグリップ１４を装着したシリンジシステム１０Ａとして製品提供されるものであってもよい。 The grip 14 may be provided as a syringe system 10A in which the grip 14 is attached to the syringe 12, as shown in FIG. 6, for example.
　また、上記のグリップ１４は、図１に示すように、シリンジ１２と、シリンジ１２のバレル１６内に摺動可能に挿入されたピストン１９と、ピストン１９を先端方向（矢印Ｚ１方向）に向かって押圧するプランジャーロッド２６と、バレル１６とピストン１９とで画成される液室内に充填された薬液Ｍと、を備え、グリップ１４がシリンジ１２のフランジ２４に装着されたプレフィルドシリンジ１０として製品提供されてもよい。 Further, as shown in FIG. 1, the grip 14 has a syringe 12, a piston 19 slidably inserted into the barrel 16 of the syringe 12, and the piston 19 directed toward the tip direction (arrow Z1 direction). A product is provided as a prefilled syringe 10 in which a plunger rod 26 for pressing and a drug solution M filled in a liquid chamber defined by a barrel 16 and a piston 19 are provided, and a grip 14 is attached to a flange 24 of the syringe 12. May be done.
（第２実施形態）
　図７Ａに示す本発明の第２実施形態に係るグリップ１４Ａは、基端壁部３４の閉塞端部４８に形成される凹部５６Ａの形状において、第１実施形態のグリップ１４（図２Ａ参照）と異なっている。なお、グリップ１４Ａにおいて、第１実施形態のグリップ１４と同様の構成については、同一の符号を付してその詳細な説明を省略する。 (Second embodiment)
A grip 14A according to the second embodiment of the present invention shown in FIG. 7A has the same shape as the grip 14 (see FIG. 2A) of the first embodiment in the shape of the recess 56A formed in the closed end portion 48 of the base end wall portion 34. Different. In the grip 14A, the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
　グリップ１４Ａの閉塞端部４８には、長手方向に離間した２つの凹部５６Ａが形成されている。軸方向からみると、図７Ｂに示すように、閉塞端部４８の中央部５０の内端部５０ａ（Ｘ１方向側の端部）は、グリップ１４Ａの長手方向（矢印Ｙ１、Ｙ２方向）に延在する直線状に形成されている。その中央部５０を挟む一対の側部５２には、半円形の基準ライン５４から突出するように２つの凹部５６Ａが形成されている。本実施形態の凹部５６Ａは、略円形の輪郭を有しており、スリット方向（矢印Ｘ２方向）及びスリット方向に垂直な方向（矢印Ｙ１、Ｙ２方向）に沿って延び出るようにして切り欠かれて形成されている。すなわち、凹部５６Ａは、基準ライン５４からスリット方向に沿って延びる第１凹部５６Ａ１と、スリット方向に垂直な方向に沿って延びる第２凹部５６Ａ２とを有する。このようにして、凹部５６Ａのスリット方向側の端部は、中央部５０よりもスリット方向側に突出するとともに、凹部５６Ａのスリット方向に垂直な方向の端部は、挿通孔４４の直径Ｗ２よりも外側に突出する。 The closed end 48 of the grip 14A is formed with two recesses 56A spaced apart in the longitudinal direction. When viewed from the axial direction, as shown in FIG. 7B, the inner end portion 50a (end portion on the X1 direction side) of the central portion 50 of the closed end portion 48 extends in the longitudinal direction (arrow Y1, Y2 direction) of the grip 14A. It is formed in the existing linear shape. Two recesses 56A are formed on a pair of side portions 52 that sandwich the central portion 50 so as to project from a semicircular reference line 54. The recess 56A of the present embodiment has a substantially circular contour, and is cut out so as to extend along the slit direction (arrow X2 direction) and the direction perpendicular to the slit direction (arrow Y1, Y2 direction). Is formed. That is, the recess 56A has a first recess 56A1 extending from the reference line 54 along the slit direction and a second recess 56A2 extending along a direction perpendicular to the slit direction. In this way, the end of the recess 56A on the slit direction side protrudes toward the slit direction from the central portion 50, and the end of the recess 56A in the direction perpendicular to the slit direction is larger than the diameter W2 of the insertion hole 44. Also protrudes outward.
　本実施形態のグリップ１４Ａは、以下の効果を奏する。 The grip 14A of this embodiment has the following effects.
　本実施形態のグリップ１４Ａは、閉塞端部４８において、中央部５０と中央部５０を挟む一対の側部５２と、一対の側部５２に開口端部４６から閉塞端部４８に向かうスリット方向（矢印Ｘ２方向）及びスリット方向に垂直な方向（矢印Ｙ１、Ｙ２方向）に沿って挿通孔４４から延び、閉塞端部４８の中央部５０に係る応力を分散する２つの凹部５６Ａを有する。本実施形態のグリップ１４Ａは、以上のように構成されることにより、グリップ１４Ａにバレル１６を装着する際の弾性変形によって閉塞端部４８に加わる曲げ応力を、２つの凹部５６Ａが形成された部分に分散することができる。これにより、閉塞端部４８の応力の集中を防いでクラックの発生を防止できる。 In the grip 14</b>A of the present embodiment, in the closed end portion 48, the central portion 50 and the pair of side portions 52 that sandwich the central portion 50, and the slit direction (from the opening end portion 46 toward the closed end portion 48) in the pair of side portions 52 ( There are two recesses 56A extending from the insertion hole 44 along the direction (arrow X2 direction) and the direction perpendicular to the slit direction (directions Y1 and Y2) and distributing the stress on the central portion 50 of the closed end 48. With the configuration of the grip 14A of the present embodiment as described above, the bending stress applied to the closed end 48 due to the elastic deformation when the barrel 16 is mounted on the grip 14A is applied to the portion where the two recesses 56A are formed. Can be dispersed in As a result, the concentration of stress on the closed end portion 48 can be prevented and the occurrence of cracks can be prevented.
　また、本実施形態のグリップ１４Ａは、２つの凹部５６Ａの各々が、挿通孔４４からスリット方向に沿って延びる第１凹部５６Ａ１と、挿通孔４４からスリット方向に垂直な方向に沿って延びる第２凹部５６Ａ２とを備える。このように、第２凹部５６Ａ２を設けることで、グリップ１４Ａの長手方向のより広い範囲に亘って、凹部５６Ａが広がるため、閉塞端部４８に係る応力もより広い範囲に分散され、閉塞端部４８のクラック防止に好適である。 In the grip 14A of the present embodiment, each of the two recesses 56A has a first recess 56A1 extending from the insertion hole 44 along the slit direction and a second recess 56A extending from the insertion hole 44 along a direction perpendicular to the slit direction. And a recess 56A2. As described above, by providing the second recessed portion 56A2, the recessed portion 56A spreads over a wider range in the longitudinal direction of the grip 14A, so that the stress related to the closed end portion 48 is also dispersed over a wider range, and the closed end portion is closed. It is suitable for preventing 48 cracks.
　また、本実施形態のグリップ１４Ａは、凹部５６Ａが頂点を有さない円形の輪郭形状に形成されている。これにより、凹部５６Ａのより広い範囲に応力が分散されるため、閉塞端部４８のクラック防止に好適である。 Further, in the grip 14A of the present embodiment, the recess 56A is formed in a circular contour shape having no apex. As a result, the stress is dispersed in a wider area of the recess 56A, which is suitable for preventing cracks in the closed end 48.
（第３実施形態）
　図８Ａに示す本発明の第３実施形態に係るグリップ１４Ｂは、基端壁部３４の閉塞端部４８に形成される凹部５６Ｂの形状において、第１実施形態のグリップ１４（図２Ａ参照）と異なっている。なお、グリップ１４Ｂにおいて、第１実施形態のグリップ１４と同様の構成については、同一の符号を付してその詳細な説明を省略する。 (Third Embodiment)
A grip 14B according to the third embodiment of the present invention shown in FIG. 8A has the same shape as the grip 14 (see FIG. 2A) of the first embodiment in the shape of the recess 56B formed in the closed end portion 48 of the base end wall portion 34. Different. In the grip 14B, the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
　グリップ１４Ｂの閉塞端部４８には、長手方向（矢印Ｙ１、Ｙ２方向）に離間した２つの凹部５６Ｂが形成されている。軸方向からみると、図８Ｂに示すように、閉塞端部４８の中央部５０の内端部５０ａは、グリップ１４Ｂの長手方向に延在する直線状に形成されている。その中央部５０を挟む一対の側部５２には、半円形の基準ライン５４から突出するように２つの凹部５６Ｂが形成されている。本実施形態の凹部５６Ｂは、スリット方向に対して傾いた矩形状の輪郭を有している。そして、凹部５６Ｂは、基準ライン５４からスリット方向に沿って延びる第１凹部５６Ｂ１と、スリット方向に垂直な方向に沿って延びる第２凹部５６Ｂ２とを有する。凹部５６Ｂの矩形状の輪郭の角部に対応する部分には、中央部５０よりもスリット方向側に突出した頂点５６ｂと、挿通孔４４の側辺４４ａよりも外側に突出した頂点５６ｃとが形成されている。 The closed end 48 of the grip 14B is formed with two recesses 56B that are separated in the longitudinal direction (arrow Y1, Y2 directions). When viewed from the axial direction, as shown in FIG. 8B, the inner end portion 50a of the central portion 50 of the closed end portion 48 is formed in a linear shape extending in the longitudinal direction of the grip 14B. Two recesses 56B are formed on a pair of side portions 52 that sandwich the central portion 50 so as to project from a semicircular reference line 54. The concave portion 56B of the present embodiment has a rectangular contour inclined with respect to the slit direction. The recess 56B has a first recess 56B1 extending from the reference line 54 along the slit direction and a second recess 56B2 extending along a direction perpendicular to the slit direction. At a portion corresponding to a corner of the rectangular contour of the recess 56B, a vertex 56b projecting to the slit direction side from the central portion 50 and a vertex 56c projecting to the outside from the side 44a of the insertion hole 44 are formed. Has been done.
　本実施形態のグリップ１４Ｂは、以下の効果を奏する。 The grip 14B of this embodiment has the following effects.
　本実施形態のグリップ１４Ｂは、２つの凹部５６Ｂの各々が、スリット方向に対して傾いた矩形状に形成され、矩形状の角部に対応する部分において、中央部５０よりもスリット方向側に突出した頂点５６ｂと、挿通孔４４の側辺４４ａより外側に突出した頂点５６ｃとが形成されている。 In the grip 14B of the present embodiment, each of the two recesses 56B is formed in a rectangular shape inclined with respect to the slit direction, and the portions corresponding to the corners of the rectangular shape project toward the slit direction side with respect to the central portion 50. The apex 56b and the apex 56c protruding outward from the side edge 44a of the insertion hole 44 are formed.
　これにより、グリップ１４Ｂの閉塞端部４８に加わる曲げ応力は、２つの凹部５６Ｂに分散される。さらに、凹部５６Ｂに作用する曲げ応力は、凹部５６Ｂ内において頂点５６ｂと頂点５６ｃとにさらに分散される。その結果、閉塞端部４８のクラック発生を防止できる。 As a result, the bending stress applied to the closed end 48 of the grip 14B is dispersed in the two recesses 56B. Further, the bending stress acting on the concave portion 56B is further dispersed in the apex 56b and the apex 56c in the concave portion 56B. As a result, it is possible to prevent cracking of the closed end portion 48.
（第４実施形態）
　図９Ａに示す本発明の第４実施形態に係るグリップ１４Ｃは、基端壁部３４の閉塞端部４８に形成される凹部５６Ｃの形状において、第１実施形態のグリップ１４（図２Ａ参照）と異なっている。なお、グリップ１４Ｃにおいて、第１実施形態のグリップ１４と同様の構成については、同一の符号を付してその詳細な説明を省略する。 (Fourth Embodiment)
A grip 14C according to the fourth embodiment of the present invention shown in FIG. 9A has a shape of a recess 56C formed in the closed end portion 48 of the base end wall portion 34, and is different from the grip 14 of the first embodiment (see FIG. 2A). Different. In the grip 14C, the same components as those of the grip 14 of the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
　グリップ１４Ｃの閉塞端部４８には、長手方向（矢印Ｙ１、Ｙ２方向）に離間した２つの凹部５６Ｃが形成されている。軸方向からみると、図９Ｂに示すように、閉塞端部４８の中央部５０及び一対の側部５２を含む内端部４８ａは、グリップ１４Ｃの長手方向に沿った直線状に形成されている。中央部５０を挟む一対の側部５２には、半円形の基準ライン５４からスリット方向に垂直な方向（矢印Ｙ１、Ｙ２方向）に沿って延びる２つの凹部５６Ｃが形成されている。本実施形態の凹部５６Ｃは、略三角形状に形成されており、その一辺は閉塞端部４８の内端部４８ａを構成する。凹部５６Ｃの頂点５６ｄは挿通孔４４の外方に突出している。 The closed end portion 48 of the grip 14C is formed with two recesses 56C that are separated in the longitudinal direction (arrow Y1, Y2 directions). When viewed from the axial direction, as shown in FIG. 9B, the inner end portion 48a including the central portion 50 and the pair of side portions 52 of the closed end portion 48 is formed in a straight line along the longitudinal direction of the grip 14C. .. Two recesses 56C extending from a semicircular reference line 54 along a direction perpendicular to the slit direction (directions of arrows Y1 and Y2) are formed in the pair of side portions 52 sandwiching the central portion 50. The recessed portion 56C of the present embodiment is formed in a substantially triangular shape, and one side thereof constitutes the inner end portion 48a of the closed end portion 48. The apex 56d of the recess 56C projects outside the insertion hole 44.
　本実施形態のグリップ１４Ｃは、以下の効果を奏する。 The grip 14C of this embodiment has the following effects.
　本実施形態のグリップ１４Ｃは、基端壁部３４において、中央部５０と、中央部５０を挟む一対の側部５２（一対の側部）と、一対の側部５２に設けられ、開口端部４６から閉塞端部４８に向かうスリット方向に垂直な方向（矢印Ｙ１、Ｙ２方向）に沿って挿通孔４４から延び、閉塞端部４８の中央部５０にかかる応力を分散する２つの凹部５６Ｃを有する。これにより、グリップ１４Ｃにバレル１６を装着する際の弾性変形による曲げ応力が２つの凹部５６Ｃに分散され、閉塞端部４８のクラック発生を防止できる。また、閉塞端部４８にクラックが発生しにくくなるため、閉塞端部４８の幅を狭くすることができ、グリップ１４Ｃを小型化することができる。 The grip 14C of the present embodiment is provided on the central end portion 50, the pair of side portions 52 (a pair of side portions) sandwiching the central portion 50, and the pair of side portions 52 in the base end wall portion 34, and the opening end portion is provided. There are two recesses 56C extending from the insertion hole 44 along a direction (arrow Y1, Y2 direction) perpendicular to the slit direction from 46 to the closed end 48 and distributing stress applied to the central portion 50 of the closed end 48. .. As a result, bending stress due to elastic deformation when the barrel 16 is attached to the grip 14C is dispersed in the two recesses 56C, and cracking of the closed end 48 can be prevented. Further, since cracks are less likely to occur in the closed end portion 48, the width of the closed end portion 48 can be narrowed and the grip 14C can be downsized.
　本発明は上述した実施形態に限定されるものではなく、本発明の趣旨を逸脱しない範囲において、種々の改変が可能である。 The present invention is not limited to the above-described embodiments, and various modifications can be made without departing from the spirit of the present invention.

Claims (9)

  1. 　外方に突出したフランジが基端部に設けられたバレルと、バレルに挿入されたプランジャーロッドと、を備えたシリンジに装着されるグリップであって、
    　先端壁部と、前記先端壁部と対向する基端壁部と、前記先端壁部と前記基端壁部とを連結する中間部と、前記先端壁部から前記基端壁部に向かって延びる中心軸と、を有するベース部と、
    　前記ベース部の側部から前記中心軸と略垂直な方向に、前記中心軸を挟んで互いに反対方向に延びる２つの指掛け部と、を備え、
    　前記中心軸及び前記２つの指掛け部の延長方向と略垂直な開口方向に開口した挿入開口部を有し、かつ、前記先端壁部と前記基端壁部とに挟まれた、前記フランジを挿入可能なフランジ装着溝を、前記中間部は備え、
    　前記先端壁部は、前記先端壁部を前記中心軸に沿って貫通し、前記フランジ装着溝と連通し、かつ、前記開口方向に開口した、前記バレルの外周面に装着可能なバレル装着部を有し、
    　前記基端壁部は、
    　前記基端壁部を前記中心軸に沿って貫通し、前記フランジ装着溝と連通した、前記プランジャーロッドを挿通可能な挿通孔と、前記挿通孔と連通し、前記開口方向に開口した開口端部と、前記開口端部と前記中心軸を挟んで対向する閉塞端部と、を有し、
    　前記閉塞端部は、中央部と、前記中央部を挟み、前記２つの指掛け部の各々と連結した一対の側部と、前記一対の側部のそれぞれに形成された２つの凹部と、を有し、
    　前記２つの凹部はそれぞれ、前記閉塞端部の前記中央部にかかる応力を分散するように、前記中心軸から離間する方向に、前記挿通孔から延びている、
    　グリップ。     A grip attached to a syringe comprising a barrel having an outwardly protruding flange provided at a base end portion, and a plunger rod inserted into the barrel,
    A distal end wall portion, a proximal end wall portion facing the distal end wall portion, an intermediate portion connecting the distal end wall portion and the proximal end wall portion, and extending from the distal end wall portion toward the proximal end wall portion A base portion having a central axis,
    Two finger hooks extending in opposite directions across the central axis in a direction substantially perpendicular to the central axis from a side portion of the base section,
    The flange that is inserted between the distal end wall portion and the proximal end wall portion and has an insertion opening portion that is opened in an opening direction that is substantially perpendicular to the extension direction of the central axis and the two finger hook portions is inserted. The intermediate portion is provided with a possible flange mounting groove,
    The distal end wall portion penetrates the distal end wall portion along the central axis, communicates with the flange mounting groove, and has a barrel mounting portion that is open in the opening direction and that can be mounted on the outer peripheral surface of the barrel. Have,
    The proximal wall portion,
    An insertion hole penetrating the base end wall portion along the central axis and communicating with the flange mounting groove and capable of inserting the plunger rod, and an opening end communicating with the insertion hole and opening in the opening direction. And a closed end portion that faces the opening end portion with the central axis interposed therebetween,
    The closed end has a central portion, a pair of side portions sandwiching the central portion and connected to each of the two finger-holding portions, and two concave portions formed in each of the pair of side portions. Then
    Each of the two recesses extends from the insertion hole in a direction away from the central axis so as to disperse the stress applied to the central portion of the closed end.
    grip.
  2. 　請求項１記載のグリップにおいて、
    　前記２つの凹部はそれぞれ、少なくとも前記開口端部から前記閉塞端部に向かうスリット方向に沿って、又は、少なくとも前記スリット方向と略垂直な方向に沿って、前記挿通孔から延びている、
    　グリップ。     The grip according to claim 1,
    Each of the two recesses extends from the insertion hole at least along a slit direction from the open end toward the closed end, or at least along a direction substantially perpendicular to the slit direction,
    grip.
  3. 　請求項１又は２記載のグリップにおいて、
    　前記中間部は、前記フランジ装着溝と連通し、かつ、前記中間部の挿入開口部と対向する貫通孔を有し、
    　前記貫通孔は、前記フランジ装着溝に挿入された前記フランジの一部を収納可能である、
    　グリップ。     The grip according to claim 1 or 2,
    The intermediate portion communicates with the flange mounting groove, and has a through hole facing the insertion opening of the intermediate portion,
    The through hole can accommodate a part of the flange inserted into the flange mounting groove,
    grip.
  4. 　請求項２記載のグリップにおいて、
    　前記閉塞端部の前記スリット方向における幅が前記中央部において最も広くなるように、前記２つの凹部が延びている、
    　グリップ。     The grip according to claim 2,
    The two recesses extend so that the width of the closed end in the slit direction is the widest in the central portion.
    grip.
  5. 　請求項４記載のグリップにおいて、
    　前記２つの凹部及び前記挿通孔の外縁とで略Ｍ字を描くように、前記２つの凹部が延びている、
    　グリップ。     The grip according to claim 4,
    The two recesses extend so as to draw a substantially M-shape with the two recesses and the outer edge of the insertion hole.
    grip.
  6. 　請求項４記載のグリップにおいて、
    　前記２つの凹部の各々は、前記スリット方向に沿って延びる第１凹部と、前記スリット方向と略垂直な方向に沿って延びる第２凹部と、を有する、
    　グリップ。     The grip according to claim 4,
    Each of the two recesses has a first recess extending along the slit direction and a second recess extending along a direction substantially perpendicular to the slit direction.
    grip.
  7. 　請求項１～６のいずれか１項に記載のグリップにおいて、
    　前記２つの凹部の各々は、基端方向から見るときに頂点を有するように延びている、
    　グリップ。     The grip according to any one of claims 1 to 6,
    Each of the two recesses extends so as to have an apex when viewed from the proximal direction,
    grip.
  8. 　請求項１～７のいずれか１項に記載のグリップと、
    　シリンジと、を備える、
    　シリンジシステム。     A grip according to any one of claims 1 to 7,
    And a syringe,
    Syringe system.
  9. 　請求項１～７のいずれか１項に記載のグリップと、
    　基端部にフランジが形成されたシリンジと、
    　前記シリンジのバレル内に摺動可能に挿入されたピストンと、
    　前記ピストンを先端方向に向かって押圧するための前記プランジャーロッドと、
    　前記バレルと前記ピストンとで画成される液室内に充填された薬液と、を備え、
    　前記グリップが前記シリンジの前記フランジに装着されている、
    　プレフィルドシリンジ。     A grip according to any one of claims 1 to 7,
    A syringe with a flange formed at the base end,
    A piston slidably inserted into the barrel of the syringe;
    The plunger rod for pressing the piston in the distal direction,
    And a liquid medicine filled in a liquid chamber defined by the barrel and the piston,
    The grip is attached to the flange of the syringe,
    Prefilled syringe.
PCT/JP2019/046528 2018-11-30 2019-11-28 Grip, and syringe system and prefilled syringe having same WO2020111173A1 (en)

Applications Claiming Priority (2)

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JP2018224362 2018-11-30
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014128383A (en) * 2012-12-28 2014-07-10 Nipro Corp Syringe
WO2014165868A1 (en) * 2013-04-03 2014-10-09 Armstrong Sean Terrence Syringe and an accessory therefor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014128383A (en) * 2012-12-28 2014-07-10 Nipro Corp Syringe
WO2014165868A1 (en) * 2013-04-03 2014-10-09 Armstrong Sean Terrence Syringe and an accessory therefor

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