WO2020106225A2 - Round-bottom tube with a triple-lock stopper - Google Patents

Round-bottom tube with a triple-lock stopper

Info

Publication number
WO2020106225A2
WO2020106225A2 PCT/TH2019/000059 TH2019000059W WO2020106225A2 WO 2020106225 A2 WO2020106225 A2 WO 2020106225A2 TH 2019000059 W TH2019000059 W TH 2019000059W WO 2020106225 A2 WO2020106225 A2 WO 2020106225A2
Authority
WO
WIPO (PCT)
Prior art keywords
triple
lock stopper
round
ridges
tube
Prior art date
Application number
PCT/TH2019/000059
Other languages
French (fr)
Other versions
WO2020106225A3 (en
Inventor
Thana TURAJANE
Original Assignee
Turajane Thana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from TH1803002684U external-priority patent/TH15297C3/en
Application filed by Turajane Thana filed Critical Turajane Thana
Publication of WO2020106225A2 publication Critical patent/WO2020106225A2/en
Publication of WO2020106225A3 publication Critical patent/WO2020106225A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes

Definitions

  • Test tubes for material storage are extensively used in medical research and hospital laboratories. For instance, whole blood fractionation involves centrifugation of blood samples in a test tube to yield fractionated products for either therapeutic or research purposes. The removal of fractionated materials from the test tube requires a pipette tip or a needle with a specific length to reach the desired layer. Otherwise, products from other layers are drawn out or the desired layer cannot be reached. Moreover, the process of uncapping the test tube and removing the materials from the test tube is conducted in an aseptic environment. Therefore, hospital facilities and research laboratories have to purchase and install laminar flow cabinets to prevent contamination of the biological samples. However, in certain cases, the use of laminar flow cabinets is optional if a proper test tube is invented.
  • the objective of the round-bottom tube with a triple-lock stopper invention is to create a sterile and closed system within the tube when adding or removing materials from the tube.
  • the invention of the round-bottom tube with a triple-lock stopper is a round-bottom test tube with an open end at the top and a closed end at the bottom, containing a removable stopper.
  • the top of the tube has outer ridges for a screw cap and inner ridges for the removable triple-lock stopper.
  • the cylinder-shaped stopper features outer threads that mesh with the inner ridges of the round-bottom tube for a secure seal.
  • the triple-lock stopper contains an axial hole located at the top end.
  • the axial hole on the triple-lock stopper fits a hollow plastic rod with two open ends.
  • the top end of the plastic rod has a rectangle shape with no inner ridges that fits a luer- lok tip syringe.
  • the bottom end of the plastic rod has a trapezoid shape with inner ridges that fit a slip tip syringe.
  • Figure 1 illustrates the complete assembly of the round-bottom tube with a triple-lock stopper embodying the present invention.
  • Figure 2 illustrates the deconstruction and individual components of a round-bottom tube with the triple-lock stopper embodying the present invention.
  • Figures 1 and 2 illustrate the complete assembly and individual components of the round- bottom tube with a triple-lock stopper.
  • the round-bottom tube (1) contains an open end at the top and a closed end at the bottom.
  • the top of the tube has outer ridges (4) for a screw cap (2) and just below the outer ridges are inner ridges (5) for a removable triple-lock stopper (6).
  • the cylinder-shaped stopper which contains an axial hole at the top end features outer threads (7) that mesh with the inner ridges (5) of the round-bottom tube.
  • the axial hole on the triple-lock stopper fits a hollow plastic rod (9) with two open ends.
  • the top end of the plastic rod has a rectangle shape with no inner ridges that fits a luer-lok tip syringe (figure not shown).
  • the bottom end of the plastic rod has a trapezoid shape with inner ridges that fit a slip tip syringe (figure not shown).
  • the interior of the axial hole on the triple-lock stopper contains ridges that mesh with the outer ridges of the hollow plastic rod to ensure the tight alignment of the syringe tip.
  • the triple-lock stopper After removing the screw cap, the triple-lock stopper remains inside the round-bottom tube.
  • the triple-lock stopper is compatible with luer-lok tip as well as slip tip syringes.
  • the two styles of syringe tip require an attachment of a needle. Once assembled, the needle punctures the thin layer of the triple-lock stopper and moves inward to access in the inner part of the round-bottom tube. The needle stops entering the tube once the syringe tip and the triple-lock stopper are aligned and locked in place.
  • the alignment mechanism of the syringe tip and the hollow plastic rod that is inserted in the axial hole on the triple-lock stopper depends on the type of the syringe tip.
  • a luer-lok tip syringe fits the top end of the plastic rod that has a rectangle shape with no inner ridges, whereas a slip tip syringe fits the bottom end of the plastic rod that has a trapezoid shape with inner ridges.
  • the clockwise rotation of this assembly releases the triple-lock stopper from the inner ridges of the round-bottom tube.
  • the pressure is applied to the syringe to slide the triple-lock stopper along the shaft of the round-bottom tube.
  • the lock between the inner ridges of the round-bottom tube and the triple-lock stopper provides a closed system for material storage.
  • the present invention of sliding the triple-lock stopper along the tube shaft allows the needle to reach the desired fractionated layer inside the tube, without removing either the screw cap or the triple-lock stopper and exposing the materials to the non-sterile environment.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention of the round-bottom tube with a triple-lock stopper is a round- bottom test tube with an open end at the top and a closed end at the bottom, containing a removable stopper. The top of the tube has outer ridges for a screw cap and inner ridges for a removable triple-lock stopper. The cylinder-shaped stopper features outer threads that mesh with the inner ridges of the round-bottom tube for a secure seal. Moreover, the triple-lock stopper contains an axial hole at its top end. The axial hole on the triple-lock stopper fits a hollow plastic rod with two open ends. The top end of the plastic rod has a rectangle shape with no inner ridges that fits a luer-lok tip syringe whereas the bottom end of the plastic rod has a trapezoid shape with inner ridges that fit a slip tip syringe.

Description

ROUND-BOTTOM TUBE WITH A TRIPLE-LOCK STOPPER
BACKGROUND OF THE INVENTION 1. Technical Field
Product engineering of the round-bottom tube with a triple-lock stopper. 2. Description of Related Art
Test tubes for material storage are extensively used in medical research and hospital laboratories. For instance, whole blood fractionation involves centrifugation of blood samples in a test tube to yield fractionated products for either therapeutic or research purposes. The removal of fractionated materials from the test tube requires a pipette tip or a needle with a specific length to reach the desired layer. Otherwise, products from other layers are drawn out or the desired layer cannot be reached. Moreover, the process of uncapping the test tube and removing the materials from the test tube is conducted in an aseptic environment. Therefore, hospital facilities and research laboratories have to purchase and install laminar flow cabinets to prevent contamination of the biological samples. However, in certain cases, the use of laminar flow cabinets is optional if a proper test tube is invented.
BREIF SUMMARY OF THE INVENTION
The objective of the round-bottom tube with a triple-lock stopper invention is to create a sterile and closed system within the tube when adding or removing materials from the tube.
The invention of the round-bottom tube with a triple-lock stopper is a round-bottom test tube with an open end at the top and a closed end at the bottom, containing a removable stopper. The top of the tube has outer ridges for a screw cap and inner ridges for the removable triple-lock stopper. The cylinder-shaped stopper features outer threads that mesh with the inner ridges of the round-bottom tube for a secure seal. In addition, the triple-lock stopper contains an axial hole located at the top end. The axial hole on the triple-lock stopper fits a hollow plastic rod with two open ends. The top end of the plastic rod has a rectangle shape with no inner ridges that fits a luer- lok tip syringe. The bottom end of the plastic rod has a trapezoid shape with inner ridges that fit a slip tip syringe.
BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWINGS
Figure 1 illustrates the complete assembly of the round-bottom tube with a triple-lock stopper embodying the present invention. Figure 2 illustrates the deconstruction and individual components of a round-bottom tube with the triple-lock stopper embodying the present invention.
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, a detailed description of this invention will be provided below with reference to embodiments thereof. Other advantages and features of this invention will be readily appreciated by those skilled in the art upon reviewing this disclosure. However, in this invention may also be implemented or applied as other embodiments, and various details in this specification may be modified and altered from different viewpoints and based on different applications without departing from the spirit of this invention.
Figures 1 and 2 illustrate the complete assembly and individual components of the round- bottom tube with a triple-lock stopper. As illustrated, the round-bottom tube (1) contains an open end at the top and a closed end at the bottom. The top of the tube has outer ridges (4) for a screw cap (2) and just below the outer ridges are inner ridges (5) for a removable triple-lock stopper (6). The cylinder-shaped stopper which contains an axial hole at the top end features outer threads (7) that mesh with the inner ridges (5) of the round-bottom tube.
The axial hole on the triple-lock stopper fits a hollow plastic rod (9) with two open ends. The top end of the plastic rod has a rectangle shape with no inner ridges that fits a luer-lok tip syringe (figure not shown). The bottom end of the plastic rod has a trapezoid shape with inner ridges that fit a slip tip syringe (figure not shown).
Between the axial hole and the base of the triple-lock stopper, which is attached to the trapezoid-shaped end of the plastic rod, is a thin layer (8) with a lower density than other components to allow smooth needle puncture and penetration (figure not shown). To create a user-friendly system, the interior of the axial hole on the triple-lock stopper contains ridges that mesh with the outer ridges of the hollow plastic rod to ensure the tight alignment of the syringe tip.
USAGE
After removing the screw cap, the triple-lock stopper remains inside the round-bottom tube. When adding or removing material to the tube, the triple-lock stopper is compatible with luer-lok tip as well as slip tip syringes.
The two styles of syringe tip require an attachment of a needle. Once assembled, the needle punctures the thin layer of the triple-lock stopper and moves inward to access in the inner part of the round-bottom tube. The needle stops entering the tube once the syringe tip and the triple-lock stopper are aligned and locked in place. The alignment mechanism of the syringe tip and the hollow plastic rod that is inserted in the axial hole on the triple-lock stopper depends on the type of the syringe tip. A luer-lok tip syringe fits the top end of the plastic rod that has a rectangle shape with no inner ridges, whereas a slip tip syringe fits the bottom end of the plastic rod that has a trapezoid shape with inner ridges.
When the syringe tip and the triple-lock stopper are locked in place, the clockwise rotation of this assembly releases the triple-lock stopper from the inner ridges of the round-bottom tube. Then, the pressure is applied to the syringe to slide the triple-lock stopper along the shaft of the round-bottom tube. The lock between the inner ridges of the round-bottom tube and the triple-lock stopper provides a closed system for material storage. In addition, the present invention of sliding the triple-lock stopper along the tube shaft allows the needle to reach the desired fractionated layer inside the tube, without removing either the screw cap or the triple-lock stopper and exposing the materials to the non-sterile environment.
Modifications, alternatives, and variations of the present invention may be made by the inventor. All changes to the present invention are not considered as a different or new invention.
Modifications, alternatives, and variations of the disclosed embodiments should be understood and realized by those skilled in the art in light of the foregoing description and equivalent constructions do not depart from the spirit and scope of the invention as described in the appended claims.

Claims

What is claimed is:
1. A tube with a triple-lock stopper comprises a round-bottom tube (1) with an open end at the top and a closed end at the bottom. The top of the tube has outer ridges (4) that mesh with the inner ridges (4) of a screw cap (2). Product Specific Features:
Inner ridges of the round-bottom tube (5) - located right below the outer ridges (4) - mesh with the triple-lock stopper (6). The cylinder-shaped stopper has a closed end at the bottom and an open end (an axial hole) at the top. The exterior part of the triple-lock stopper contains threads (7) that mesh with the inner ridges (5) of the round-bottom tube. The axial hole located at the top end of the triple-lock stopper fits a hollow plastic rod
(9) with two open ends. The top end of the plastic rod has a rectangle shape with no inner ridges to fits a luer-lok tip syringe. The bottom end of the plastic rod has a trapezoid shape with inner ridges to fit a slip tip syringe.
Between the axial hole and the base of the triple-lock stoppers (6), that is attached to the trapezoid-shaped end of the plastic rod, is a thin layer (8) with lower density than other components of this invention to allow smooth needle puncture and penetration.
2. The round-bottom tube with a triple-lock stopper of claim 1 wherein said indexing means comprises an axial hole, located at the top end of the triple-lock stopper, with inner ridges that mesh with the outer ridges of the hollow plastic rod for tight alignment with the syringe tip.
3. The round-bottom tube with a triple-lock stopper of claim 1 wherein said indexing means comprises a hollow plastic rod with outer ridges that mesh with the inner ridges of the triple-lock stopper.
PCT/TH2019/000059 2018-11-19 2019-11-15 Round-bottom tube with a triple-lock stopper WO2020106225A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TH1803002684U TH15297C3 (en) 2018-11-19 Sliding-lock cap ampoule
TH1803002684 2018-11-19

Publications (2)

Publication Number Publication Date
WO2020106225A2 true WO2020106225A2 (en) 2020-05-28
WO2020106225A3 WO2020106225A3 (en) 2020-06-25

Family

ID=70773944

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TH2019/000059 WO2020106225A2 (en) 2018-11-19 2019-11-15 Round-bottom tube with a triple-lock stopper

Country Status (1)

Country Link
WO (1) WO2020106225A2 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0435575U (en) * 1990-07-18 1992-03-25
US6382442B1 (en) * 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
JP3761411B2 (en) * 2000-10-02 2006-03-29 フカイ工業株式会社 Plug body with check valve
FR2836129B1 (en) * 2002-02-20 2004-04-02 Biodome CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE
WO2008058326A1 (en) * 2006-11-13 2008-05-22 Baker Raymond J Closure and dispensing system
ITMI20121133A1 (en) * 2012-06-27 2013-12-28 Frattini Paolo Giuseppe Gobbi BOTTLE FOR PHARMACOLOGICAL AND / OR NUTRITIONAL ACTIVE SUBSTANCES WITH PERFORABLE ERMETIC CLOSURE WITH NEEDLE SYRINGE AND AUTOMATICALLY CLOSABLE TO HOLD.
WO2014051037A1 (en) * 2012-09-28 2014-04-03 積水メディカル株式会社 Tube body, blood collection tube, and method for manufacturing tube body
WO2014026721A1 (en) * 2012-12-21 2014-02-20 Peter Skufca Primary packaging for storage and/or administration of medical or pharmaceutical compounds and method for assembling such a primary packaging

Also Published As

Publication number Publication date
WO2020106225A3 (en) 2020-06-25

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