WO2020075811A1 - Reagent bottle cap and reagent container - Google Patents

Reagent bottle cap and reagent container Download PDF

Info

Publication number
WO2020075811A1
WO2020075811A1 PCT/JP2019/040045 JP2019040045W WO2020075811A1 WO 2020075811 A1 WO2020075811 A1 WO 2020075811A1 JP 2019040045 W JP2019040045 W JP 2019040045W WO 2020075811 A1 WO2020075811 A1 WO 2020075811A1
Authority
WO
WIPO (PCT)
Prior art keywords
reagent
cap
bottle
reagent bottle
opening
Prior art date
Application number
PCT/JP2019/040045
Other languages
French (fr)
Japanese (ja)
Inventor
美幸 東
Original Assignee
株式会社Ｌｓｉメディエンス
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社Ｌｓｉメディエンス filed Critical 株式会社Ｌｓｉメディエンス
Priority to JP2020551227A priority Critical patent/JPWO2020075811A1/en
Publication of WO2020075811A1 publication Critical patent/WO2020075811A1/en

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/08—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages having articulated or hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/02—Loosely-engaging lids or covers for jars, cans, or like containers for liquids without means for effecting sealing of container
    • B65D51/04—Loosely-engaging lids or covers for jars, cans, or like containers for liquids without means for effecting sealing of container hinged
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Definitions

  • the present invention relates to a reagent bottle cap and a reagent container.
  • an automatic analyzer (automatic measuring device) that measures components in a biological sample such as a blood sample or a urine sample
  • a biological sample such as a blood sample or a urine sample
  • Patent Document 1 an automatic analyzer (automatic measuring device) that measures components in a biological sample such as a blood sample or a urine sample
  • This kind of automatic analyzer usually has a disk-shaped reagent table for installing a large number of reagent bottles filled with liquid reagents used in various measurements.
  • the reagent table has, for example, bottle holding units for holding the reagent bottles arranged in an annular shape, and by installing the reagent bottles in each bottle holding unit, the reagent bottles have an annular shape in the reagent table. It is arranged and held.
  • a reagent bottle cap that can open and close the opening of the reagent bottle is essential. Further, the reagent bottle cap is automatically opened / closed each time the reagent is dispensed by the dispensing nozzle, for example, by the opening / closing unit included in the automatic measuring device.
  • an automatic measuring device with a vortex mixing function has been put into practical use, in which the bottom of the reagent bottle installed in the holding part of the reagent table is swung at high speed to stir the reagent in a non-contact manner.
  • an automatic measuring device equipped with such an automatic opening / closing function for the reagent bottle cap and an automatic stirring function for the reagent bottle the orientation of the reagent bottle cap is excessive while allowing a degree of movement necessary for stirring the reagent.
  • the engagement member provided on the reagent table engages with the engaged portion provided on the reagent bottle cap so as not to shift.
  • the reagent bottle used in the automatic measurement device has a sticker printed with a barcode for managing reagent information by barcode. Then, the reagent bottle is identified by rotating the reagent table and stopping the target reagent bottle at a position where the barcode reader fixed around the reagent table can read it. By the way, in order to read the barcode attached to the reagent bottle by the barcode reader, it is necessary to install the reagent bottle in the bottle holder with the barcode oriented in an appropriate direction.
  • the reagent bottle cap is fixed to the reagent bottle. Therefore, the relative positional relationship between the engaged portion provided on the reagent bottle cap and the barcode attached to the reagent bottle may not be appropriate.
  • the reagent bottle when the reagent bottle is installed in the bottle holding portion while engaging the engaging member of the reagent table and the engaged portion of the reagent bottle cap, the reagent bottle should be oriented with the barcode in the proper direction. It could not be installed, and there was a risk of causing an error in reading the barcode attached to the reagent bottle. Therefore, it is managed and used by separately preparing a bar code and attaching it to an appropriate place, but there is a problem because it is complicated and a mistake may occur.
  • the present invention has been made in view of the above problems, and an object thereof is to easily set the orientation and the reagent of the specific portion on the reagent bottle cap side when the reagent bottle is installed in the bottle holding portion. It is an object of the present invention to provide a technology relating to a reagent bottle cap that allows the orientation of a specific portion on the bottle side to be arranged in a desired relationship.
  • a cap for a reagent bottle according to the present invention for solving the above problems is an attachment portion fixed to a mouth portion of a reagent bottle, and is rotatably attached to the attachment portion, and the mouth portion can be opened and closed. And an opening / closing cap portion having a transparent lid body.
  • the opening / closing cap portion may be provided with an engaged portion capable of engaging with an engaging member provided on the installation object of the reagent bottle.
  • the object to be installed is a reagent table of an analyzer for analyzing components in a biological sample
  • the engaging member is directed upward from the reagent table in the vicinity of a bottle installation section formed on the reagent table.
  • the engaged portion may have a tubular portion through which the shaft member can be inserted.
  • the attachment part may be configured to be screwed to a screw part formed in the mouth part.
  • the present invention can be specified as a reagent container. That is, the reagent container according to the present invention has any one of the above-described reagent bottle caps, a mouth portion to which the attachment portion of the reagent bottle cap is fixed, and a bottle body capable of filling a reagent therein. And a reagent bottle.
  • identification information about the reagent may be attached to the side surface of the bottle body.
  • the reagent bottle when the reagent bottle is installed in the bottle holding portion, it is possible to easily arrange the orientation of the specific portion on the reagent bottle cap side and the orientation of the specific portion on the reagent bottle side in a desired relationship. It is possible to provide a technology relating to a reagent bottle cap.
  • FIG. 1 is a diagram showing a reagent container in the embodiment.
  • FIG. 2 is a schematic diagram of a reagent bottle.
  • FIG. 3 is a view showing the attachment part of the reagent bottle cap.
  • FIG. 4 is a view showing the opening / closing cap portion of the reagent bottle cap.
  • FIG. 5 is a view showing a part of the reagent container in which the lid body is in the closed posture.
  • FIG. 6 is a diagram showing an example of the analyzer.
  • FIG. 7 is a diagram illustrating a reagent table in the analyzer.
  • FIG. 8 is a diagram illustrating a cap opening / closing unit in the analyzer.
  • FIG. 1 is a diagram showing a reagent container 10 in the embodiment.
  • the reagent container 10 includes a reagent bottle 20 and a reagent bottle cap 30 attached to the reagent bottle 20.
  • the reagent container 10 is, for example, a container for filling a liquid reagent used for various measurements of an analyzer that analyzes components in a biological sample such as a blood sample or a urine sample.
  • FIG. 2 is a schematic diagram of the reagent bottle 20.
  • the reagent bottle 20 has a bottle body 21 capable of storing a liquid reagent filled therein, and a mouth portion 22 provided on an upper portion of the bottle body 21.
  • the bottle body 21 of the reagent bottle 20 has a substantially columnar outer shape.
  • an identification information sticker 50 on which identification information 40 such as a barcode or a two-dimensional code is displayed by printing is attached.
  • the aspect in which the identification information 40 is attached to the side surface 211 of the bottle body 21 is not particularly limited.
  • a film on which the identification information 40 is printed may be wound on the side surface 211 of the bottle body 21, or the identification information 40 may be directly printed on the side surface 211 of the bottle body 21.
  • the identification information 40 includes, for example, identification information regarding the liquid reagent filled in the reagent bottle 20.
  • the mouth 22 of the reagent bottle 20 has a cylindrical shape, and the lower end of the mouth 22 is connected to the bottle body 21.
  • the upper end of the mouth 22 is an open end, and an opening 221 is formed.
  • the bottle body 21 of the reagent bottle 20 can store the liquid reagent filled therein through the opening 221 formed in the mouth 22.
  • an outer screw 222 for attaching the reagent bottle cap 30 is formed on the outer peripheral surface 22 a of the mouth portion 22.
  • the reagent bottle cap 30 includes an attachment portion 31 fixed to the mouth portion 22 of the bottle body 21, and an opening / closing cap portion 32 rotatably attached to the attachment portion 31.
  • the reagent bottle cap 30 can be manufactured, for example, by molding a resin.
  • FIG. 3 and 4 are exploded views of the reagent bottle cap 30.
  • FIG. 3 is a view showing the attachment part 31 of the reagent bottle cap 30.
  • FIG. 4 is a view showing the opening / closing cap portion 32 of the reagent bottle cap 30.
  • the attachment part 31 has a fixing part 311 which is fitted around the mouth part 22 of the reagent bottle 20 and fixed to the mouth part 22.
  • the fixed portion 311 has an inner peripheral surface having an inner diameter substantially equal to the outer diameter of the mouth portion 22, and the inner peripheral surface has an outer screw formed on the outer peripheral surface 22a of the mouth portion 22 of the reagent bottle 20.
  • a thread groove (not shown) that can be screwed into 222 is formed.
  • the size of the attachment part 31 and the cap body can be appropriately designed by those skilled in the art, but the size of the fixing part 311 in the attachment part 31 is designed according to the diameter of the mouth part 22, and will be described later.
  • the size of the mounting portion 312 to be mounted is preferably designed according to the diameter of the side wall portion 324 of the cap body 321 of a predetermined standard on the inner peripheral surface side.
  • a mounting part 312 is provided above the fixing part 311.
  • Engagement protrusions 313 for rotatably mounting the opening / closing cap portion 32 are formed on the outer peripheral surface 312a of the mounting portion 312 of the attachment portion 31 over the entire circumference of the outer peripheral surface 312a of the mounting portion 312. ing.
  • the open / close cap unit 32 includes a cap body 321 that is rotatably attached to the attachment unit 31, and a lid 322 that can open and close the opening 221 of the mouth 22 of the reagent bottle 20.
  • the cap body 321 and the lid 322 in the open / close cap unit 32 are connected via a hinge 323.
  • the cap body 321 is a member having a topped cylindrical shape, and includes a cylindrical side wall portion 324 and a top wall portion 325 that is continuous with the upper end of the side wall portion 324.
  • a cap opening 326 is formed on the center side of the top wall 325.
  • the cap opening 326 in this embodiment has a circular cross section, but may have another shape.
  • an engaging portion 327 that engages with the engaging protrusion 313 of the mounting portion 312 of the attachment portion 31 is provided.
  • the engagement portion 327 of the cap body 321 and the engagement protrusion 313 of the mounting portion 312 of the attachment portion 31 are engaged with each other, so that the attachment portion 31 and the cap body 321 can rotate relative to each other, and the attachment portion 31 can be rotated.
  • the cap body 321 is prevented from coming off.
  • the engaging portion 327 of the cap body 321 may be a fitting groove into which the engaging protrusion 313 of the attachment portion 31 can be loosely fitted.
  • the rotation axis when the attachment part 31 and the cap body 321 rotate relative to each other is coaxial with the central axis of the mouth 22 of the reagent bottle 20 and orthogonal to the bottom of the bottle body 21.
  • the engaging portions 327 of the cap body 321 are provided at a plurality of locations along the circumferential direction of the side wall portion 324. In the example shown in FIG. 4, the engaging portions 327 of the cap body 321 are arranged at a total of four locations, which are rotated by 90 ° along the circumferential direction of the side wall portion 324, but are not limited to this.
  • the side wall portion 324 of the cap body 321 in the present embodiment is provided with an engaged portion 328 that can engage with an engaging member provided on the installation object of the reagent bottle 20.
  • the engaged portion 328 has a support piece 329 protruding laterally from the outer surface of the side wall portion 324 and a cylindrical sleeve 330 supported by the support piece 329, as shown in FIG. .
  • the central axis of the cylindrical sleeve 330 is parallel to the central axis CL of the side wall portion 324 of the cap body 321.
  • the lid 322 of the reagent bottle cap 30 is rotatably connected to the cap body 321 via a hinge 323.
  • the hinge axis of the hinge 323 is orthogonal to the central axis of the side wall portion 324 of the cap body 321.
  • the hinge 323 and the engaged portion 328 are located at positions symmetrical with respect to the central axis CL of the cap body 321 (positions shifted by 180 ° around the central axis). It is arranged.
  • FIG. 5 is a diagram showing a part of the reagent container 10 in which the lid 322 is in the closed posture.
  • a sealing member 331 for sealing the cap opening 326 by being inserted into the cap opening 326 in the closed posture is provided on the lower surface 322a of the lid 322 so as to protrude downward from the lower surface 322a.
  • the sealing member 331 has a cylindrical shape, and its outer diameter is equal to the diameter of the cap opening 326. Note that the sealing member 331 may seal the cap opening 326 when the lid 322 is closed, and can smoothly perform repeated opening / closing operations, depending on the shape, size, or the like of the cap opening 326. Various forms can be adopted.
  • a lid opening operation convex portion 332 is provided on the upper surface 322b of the lid body 322 so as to project upward.
  • the lid-opening operation convex portion 332 is a flat plate-like projecting member that stands upright from the upper surface 322b of the lid body 322.
  • the lateral width direction of the lid-opening operation convex portion 332 extends parallel to the hinge axis of the hinge 323.
  • the lid opening operation convex portion 332 is operated by the cap opening / closing unit when the cap opening / closing unit included in the analyzer to which the reagent container 10 is applied opens the reagent bottle cap 30, for example.
  • the reagent container 10 is completed by attaching the reagent bottle cap 30 to the mouth portion 22 of the reagent bottle 20 described above. That is, the attachment portion 31 is attached to the mouth portion 22 of the reagent bottle 20, and the opening / closing cap portion 32 is attached to the attachment portion 31 so as to be rotatable relative to each other.
  • the attachment part 31 is attached to the mouth part 22 of the reagent bottle 20 by screwing a screw groove provided in the fixing part 311 onto an outer screw 222 formed on the outer peripheral surface 22 a of the mouth part 22. Can be fixed together.
  • the reagent bottle cap 30 is fitted into the attachment portion 31 fixed to the mouth portion 22 of the reagent bottle 20 from above, and the side wall portion of the cap body 321 is fitted to the engaging protrusion 313 of the mounting portion 312 of the attachment portion 31.
  • the engaging portion 327 of 324 is engaged.
  • the opening / closing cap portion 32 can be attached to the attachment portion 31 so as to be rotatable relative to each other, and the reagent container 10 as shown in FIG. 1 is completed.
  • the opening 221 of the mouth 22 of the reagent bottle 20 communicates with the cap opening 326 of the opening / closing cap 32.
  • the cap opening 326 is sealed by the sealing member 331 of the lid 322.
  • the reagent container 10 (reagent bottle 20) is sealed. be able to.
  • the reagent in the reagent bottle 20 can be prevented from evaporating and the deterioration due to the contact with the air can be suppressed.
  • the lid 322 is rotated about the hinge axis in the opening / closing cap portion 32 to switch the lid 322 from the closed posture to the open posture, whereby the opening 221 of the mouth 22 of the reagent bottle 20 and the cap opening.
  • the part 326 is opened.
  • the attachment portion 31 fixed to the mouth portion 22 of the reagent bottle 20 the attachment portion 31 rotatably attached to the attachment portion 31, and the mouth portion 22 Since the opening / closing cap portion 32 having the lid 322 that can be opened and closed is provided, the orientation of the identification information 40 (identification information seal 50) attached to the side surface 211 of the reagent bottle 20 and the reagent bottle cap 30 (opening / closing cap portion).
  • the direction of the engaged portion 328 (cylindrical sleeve 330) in 32) can be adjusted to any relationship.
  • the reagent container 10 is set at a predetermined position in the analyzer 1000 as shown in FIG. 6, for example.
  • the analysis device 1000 is a device that analyzes components in a biological sample.
  • Reference numeral C shown in FIG. 6 is a reagent storage cover.
  • the user can set the reagent container 10 in the reagent container by opening the reagent container cover C.
  • the bottle cap is replaced with the reagent bottle cap 30 according to the present embodiment, and then the analyzer 1000. It may be set at a predetermined position in.
  • the reagent bottle 10 in the present embodiment may be shipped in the state of the reagent container 10 in which the reagent bottle cap 30 is attached.
  • FIG. 7 is a diagram showing a part of the reagent table 104 installed in the reagent storage in the analyzer 1000.
  • the reagent table 104 is a disk-shaped table that rotates about a predetermined rotation axis, and a plurality of bottle installation units 1041 for holding (installing) the reagent container 10 (reagent bottle 20) are annularly formed on the table. It is arranged.
  • the bottle installation unit 1041 is a recess that can accommodate the lower side of the reagent container 10 (reagent bottle 20) and can hold the accommodated reagent container 10 (reagent bottle 20).
  • the reagent table 104 corresponds to the installation object of the reagent bottle.
  • the reagent table 104 is provided with a rod-shaped member 1042 protruding vertically upward in the vicinity of the bottle setting unit 1041.
  • the rod-shaped member 1042 is provided corresponding to each bottle installation section 1041, and is arranged at a position on the rotation axis side of the reagent table 104 with respect to the corresponding bottle installation section 1041.
  • the user When installing the reagent container 10 (reagent bottle 20) in the bottle installation section 1041, the user places the rod-shaped member 1042 on the cylindrical sleeve 330 (engaged section 328) of the reagent bottle cap 30 (open / close cap section 32). Insert from.
  • the white arrow D in FIG. 7 indicates the direction in which the identification information 40 (identification information seal 50) of the reagent bottle 20 is directed when the reagent container 10 (reagent bottle 20) is installed in the bottle installation section 1041. It is a thing.
  • the identification information 40 of each reagent bottle 20 is read by a reading device (not shown) such as a bar code reader fixed around the reagent table 104. Therefore, as shown by the arrow D in FIG. 7, it is necessary to set the reagent bottle 20 in each bottle installation unit 1041 so that the identification information 40 is directed outward in the radial direction of the reagent table 104.
  • the user when the user installs the reagent bottle 20 in the bottle installation section 1041 of the reagent table 104, the user can easily insert the bar-shaped member 1042 into the cylindrical sleeve 330 (engaged section 328) and display the identification information 40 on the bar. It is possible to properly orient the device in a proper direction that can be read by a reading device such as a code reader. Therefore, the reading error of the identification information 40 attached to the reagent bottle 20 can be suppressed.
  • the orientation of the cylindrical sleeve 330 (engaged portion 328) in the opening / closing cap portion 32 and the orientation of the identification information 40 attached to the reagent bottle 20 correspond to the specific portion on the reagent bottle cap side. This corresponds to a combination of the orientation and the orientation of the specific portion on the reagent bottle side.
  • FIG. 8 is a diagram for explaining the cap opening / closing unit 105 in the analyzer 1000.
  • the cap opening / closing unit 105 is a unit for opening / closing the lid 322 of the reagent bottle cap 30 in the reagent container 10 installed in the bottle installation unit 1041.
  • the cap opening / closing unit 105 has an opening / closing operation tool 1051 which can be displaced in the radial direction of the reagent table 104 and vertically displaced by a drive mechanism. For example, when the cap opening / closing unit 105 opens / closes the lid 322 of the target reagent container 10, the reagent table 104 is rotated to move the opening / closing operation tool 1051 on the orbit along which the reagent container 10 moves, and rotationally moves.
  • the lid 322 can be opened and closed by colliding (contacting) the opening / closing operation tool 1051 with the lid 322 of the reagent container 10.
  • the opening / closing operation tool 1051 is made to collide.
  • a rotation moment acts on the hinge 323 as a fulcrum in the opening direction in which the lid 322 opens, and the lid 322 is opened.
  • the reagent table 104 is rotated in the opposite direction to the opening of the reagent container 10 and the opening / closing operation tool 1051 is collided with the lid 322.
  • a rotational moment in the closing direction acts on the lid body 322.
  • the reagent to be closed vertically below the opening / closing operation tool 1051.
  • the cap opening / closing unit 105 may vertically displace the opening / closing operation tool 1051 so that the opening / closing operation tool 1051 presses the upper surface 322b of the lid 322 toward the lower cap body 321 side.
  • the cap opening 326 of the cap body 321 is sealed by the sealing member 331, and the reagent container 10 can be sealed.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Closures For Containers (AREA)

Abstract

Provided is a technology relating to a reagent bottle cap that makes it possible to have a desired relationship between the direction of a specific portion on the reagent bottle cap side and the direction of a specific portion on the reagent bottle side. The reagent bottle cap is provided with: an attachment part that is adhered to a mouth part of a reagent bottle; and an opening/closing cap part that is rotatably attached to the attachment part and has a lid body capable of freely opening/closing the mouth part.

Description

試薬ボトル用キャップ及び試薬容器Reagent bottle cap and reagent container
　本発明は、試薬ボトル用キャップ及び試薬容器に関する。 The present invention relates to a reagent bottle cap and a reagent container.
　従来、血液サンプルや尿サンプル等の生体サンプル中の成分を測定する自動分析装置（自動測定装置）が知られている（例えば特許文献１）。この種の自動分析装置は、通常、各種測定で使用する液状の試薬が充填された多数の試薬ボトルを設置するためのディスク状の試薬テーブルを有している。試薬テーブルは、例えば、試薬ボトルを保持するためのボトル保持部が円環状に配列して設けられており、各ボトル保持部に試薬ボトルを設置することで、試薬テーブルに試薬ボトルが円環状に配列して保持されるようになっている。 Conventionally, an automatic analyzer (automatic measuring device) that measures components in a biological sample such as a blood sample or a urine sample is known (for example, Patent Document 1). This kind of automatic analyzer usually has a disk-shaped reagent table for installing a large number of reagent bottles filled with liquid reagents used in various measurements. The reagent table has, for example, bottle holding units for holding the reagent bottles arranged in an annular shape, and by installing the reagent bottles in each bottle holding unit, the reagent bottles have an annular shape in the reagent table. It is arranged and held.
　また、試薬ボトルは、試薬の蒸発、あるいは空気との接触による試薬の変質を抑制する必要があるため、試薬ボトルの開口部を開閉可能な試薬ボトル用キャップが必須となる。また、試薬ボトル用キャップは、分注ノズルによる試薬の分注を行う度に、例えば自動測定装置が備える開閉ユニットによって開閉が自動で行われる。 Also, since it is necessary to prevent the reagent bottle from deteriorating due to evaporation of the reagent or contact with air, a reagent bottle cap that can open and close the opening of the reagent bottle is essential. Further, the reagent bottle cap is automatically opened / closed each time the reagent is dispensed by the dispensing nozzle, for example, by the opening / closing unit included in the automatic measuring device.
　また、近年では、試薬テーブルの保持部に設置されている試薬ボトルの底部を高速旋回させて試薬を非接触で撹拌するボルテックスミキシング機能を有する自動測定装置が実用化されている。このような試薬ボトル用キャップの自動開閉機能と試薬ボトルの自動撹拌機能を備えた自動測定装置においては、試薬の攪拌に必要な程度の動きは許容しつつ、試薬ボトル用キャップの向きが過度にずれないように、試薬テーブルに設けられた係合部材によって試薬ボトル用キャップに設けられた被係合部を係合している。 Also, in recent years, an automatic measuring device with a vortex mixing function has been put into practical use, in which the bottom of the reagent bottle installed in the holding part of the reagent table is swung at high speed to stir the reagent in a non-contact manner. In an automatic measuring device equipped with such an automatic opening / closing function for the reagent bottle cap and an automatic stirring function for the reagent bottle, the orientation of the reagent bottle cap is excessive while allowing a degree of movement necessary for stirring the reagent. The engagement member provided on the reagent table engages with the engaged portion provided on the reagent bottle cap so as not to shift.
　また、自動測定装置に用いる試薬ボトルには、試薬の情報管理をバーコードによって行うためのバーコードが印刷されたシール等が貼り付けられている。そして、試薬テーブルを回転させることで試薬テーブルの周辺に固定されているバーコードリーダの読み取り可能な位置に対象の試薬ボトルを停止させることで、試薬ボトルの識別を行っている。ところで、バーコードリーダによって、試薬ボトルに付されたバーコードを読み取るためには、バーコードを適正な方向に向けてボトル保持部に試薬ボトルを設置する必要がある。 Also, the reagent bottle used in the automatic measurement device has a sticker printed with a barcode for managing reagent information by barcode. Then, the reagent bottle is identified by rotating the reagent table and stopping the target reagent bottle at a position where the barcode reader fixed around the reagent table can read it. By the way, in order to read the barcode attached to the reagent bottle by the barcode reader, it is necessary to install the reagent bottle in the bottle holder with the barcode oriented in an appropriate direction.
国際公開第２００６／１０７０１６号International Publication No. 2006/107016
　しかしながら、従来、試薬ボトルに対して試薬ボトル用キャップは固着されている。そのため、試薬ボトル用キャップに設けられた被係合部と、試薬ボトルに付されたバーコードの相対位置関係が適正でない場合がある。そのような場合、試薬テーブルの係合部材と試薬ボトル用キャップの被係合部を係合させつつボトル保持部に試薬ボトルを設置した際に、バーコードを適正な方向に向けて試薬ボトルを設置することができず、試薬ボトルに付されたバーコードの読み取りエラーを招く虞があった。そのため、別途、バーコードを用意し、適切な場所に貼付することで管理・使用することが行われているが、煩雑であり、間違いが生じる可能性等があるため、課題があった。本発明は、上記のような問題点に鑑みてなされたものであって、その目的は、試薬ボトルをボトル保持部に設置する際に、容易に試薬ボトル用キャップ側の特定部位の向きと試薬ボトル側の特定部位の向きを所望の関係にして配置することを可能とする試薬ボトル用キャップに関する技術を提供することにある。 However, conventionally, the reagent bottle cap is fixed to the reagent bottle. Therefore, the relative positional relationship between the engaged portion provided on the reagent bottle cap and the barcode attached to the reagent bottle may not be appropriate. In such a case, when the reagent bottle is installed in the bottle holding portion while engaging the engaging member of the reagent table and the engaged portion of the reagent bottle cap, the reagent bottle should be oriented with the barcode in the proper direction. It could not be installed, and there was a risk of causing an error in reading the barcode attached to the reagent bottle. Therefore, it is managed and used by separately preparing a bar code and attaching it to an appropriate place, but there is a problem because it is complicated and a mistake may occur. The present invention has been made in view of the above problems, and an object thereof is to easily set the orientation and the reagent of the specific portion on the reagent bottle cap side when the reagent bottle is installed in the bottle holding portion. It is an object of the present invention to provide a technology relating to a reagent bottle cap that allows the orientation of a specific portion on the bottle side to be arranged in a desired relationship.
　上記課題を解決するための本発明に係る試薬ボトル用キャップは、試薬ボトルの口部に固着されるアタッチメント部と、前記アタッチメント部に対して回動自在に取り付けられると共に、前記口部を開閉自在な蓋体を有する開閉キャップ部と、を備えることを特徴とする。 A cap for a reagent bottle according to the present invention for solving the above problems is an attachment portion fixed to a mouth portion of a reagent bottle, and is rotatably attached to the attachment portion, and the mouth portion can be opened and closed. And an opening / closing cap portion having a transparent lid body.
　また、前記開閉キャップ部に、前記試薬ボトルの設置対象物に設けられた係合部材と係合可能な被係合部が設けられていてもよい。 Further, the opening / closing cap portion may be provided with an engaged portion capable of engaging with an engaging member provided on the installation object of the reagent bottle.
　また、前記設置対象物は、生体サンプル中の成分を分析する分析装置の試薬テーブルであり、前記係合部材は、前記試薬テーブルに形成されたボトル設置部の近傍において当該試薬テーブルから上方に向けて突設された棒状部材であり、前記被係合部は、前記軸部材を挿通可能な筒部を有していてもよい。 Further, the object to be installed is a reagent table of an analyzer for analyzing components in a biological sample, and the engaging member is directed upward from the reagent table in the vicinity of a bottle installation section formed on the reagent table. And the engaged portion may have a tubular portion through which the shaft member can be inserted.
　また、前記アタッチメント部は、前記口部に形成されたネジ部に螺着されるように構成されていてもよい。 Also, the attachment part may be configured to be screwed to a screw part formed in the mouth part.
　また、本発明は、試薬容器として特定することができる。すなわち、本発明に係る試薬容器は、上述までの何れかの試薬ボトル用キャップと、前記試薬ボトル用キャップにおける前記アタッチメント部が固着される口部、及び内部に試薬を充填可能なボトル本体を有する試薬ボトルと、を備える。 Also, the present invention can be specified as a reagent container. That is, the reagent container according to the present invention has any one of the above-described reagent bottle caps, a mouth portion to which the attachment portion of the reagent bottle cap is fixed, and a bottle body capable of filling a reagent therein. And a reagent bottle.
　また、試薬容器において、前記ボトル本体の側面に、試薬に関する識別情報が付されていてもよい。 Also, in the reagent container, identification information about the reagent may be attached to the side surface of the bottle body.
　本発明によれば、試薬ボトルをボトル保持部に設置する際に、容易に試薬ボトル用キャップ側の特定部位の向きと試薬ボトル側の特定部位の向きを所望の関係にして配置することを可能とする試薬ボトル用キャップに関する技術を提供できる。 According to the present invention, when the reagent bottle is installed in the bottle holding portion, it is possible to easily arrange the orientation of the specific portion on the reagent bottle cap side and the orientation of the specific portion on the reagent bottle side in a desired relationship. It is possible to provide a technology relating to a reagent bottle cap.
図１は、実施形態における試薬容器を示す図である。FIG. 1 is a diagram showing a reagent container in the embodiment. 図２は、試薬ボトルの概略図である。FIG. 2 is a schematic diagram of a reagent bottle. 図３は、試薬ボトル用キャップのアタッチメント部を示す図である。FIG. 3 is a view showing the attachment part of the reagent bottle cap. 図４は、試薬ボトル用キャップの開閉キャップ部を示す図である。FIG. 4 is a view showing the opening / closing cap portion of the reagent bottle cap. 図５は、蓋体が閉蓋姿勢にある試薬容器の一部を示す図である。FIG. 5 is a view showing a part of the reagent container in which the lid body is in the closed posture. 図６は、分析装置の一例を示す図である。FIG. 6 is a diagram showing an example of the analyzer. 図７は、分析装置における試薬テーブルを説明する図である。FIG. 7 is a diagram illustrating a reagent table in the analyzer. 図８は、分析装置におけるキャップ開閉ユニットを説明する図である。FIG. 8 is a diagram illustrating a cap opening / closing unit in the analyzer.
　以下、実施形態に係る試薬ボトル用キャップ及び当該キャップを備える試薬容器について、図面を用いて説明する。 Hereinafter, a reagent bottle cap and a reagent container including the cap according to the embodiment will be described with reference to the drawings.
＜全体構成＞
　図１は、実施形態における試薬容器１０を示す図である。試薬容器１０は、試薬ボトル２０と、当該試薬ボトル２０に取り付けられた試薬ボトル用キャップ３０を具備している。試薬容器１０は、例えば、血液サンプルや尿サンプル等の生体サンプル中の成分を分析する分析装置の各種測定に使用する液状の試薬を充填するための容器である。 <Overall configuration>
FIG. 1 is a diagram showing a reagent container 10 in the embodiment. The reagent container 10 includes a reagent bottle 20 and a reagent bottle cap 30 attached to the reagent bottle 20. The reagent container 10 is, for example, a container for filling a liquid reagent used for various measurements of an analyzer that analyzes components in a biological sample such as a blood sample or a urine sample.
　図２は、試薬ボトル２０の概略図である。試薬ボトル２０は、内部に充填される液状の試薬を貯留可能なボトル本体２１と、ボトル本体２１の上部に設けられた口部２２を有する。試薬ボトル２０のボトル本体２１は略円柱形状の外形を有している。また、ボトル本体２１の側面２１１には、バーコードや二次元コード等の識別情報４０が印刷などによって表示された識別情報シール５０が貼り付けられている。なお、ボトル本体２１の側面２１１に識別情報４０（図１を参照）を付す態様については特に限定されない。例えば、ボトル本体２１の側面２１１に識別情報４０が印刷されたフィルムが巻かれていてもよいし、ボトル本体２１の側面２１１に識別情報４０を直接印刷してもよい。なお、識別情報４０は、例えば、試薬ボトル２０に充填される液状の試薬に関する識別情報を含む。 FIG. 2 is a schematic diagram of the reagent bottle 20. The reagent bottle 20 has a bottle body 21 capable of storing a liquid reagent filled therein, and a mouth portion 22 provided on an upper portion of the bottle body 21. The bottle body 21 of the reagent bottle 20 has a substantially columnar outer shape. Further, on the side surface 211 of the bottle body 21, an identification information sticker 50 on which identification information 40 such as a barcode or a two-dimensional code is displayed by printing is attached. The aspect in which the identification information 40 (see FIG. 1) is attached to the side surface 211 of the bottle body 21 is not particularly limited. For example, a film on which the identification information 40 is printed may be wound on the side surface 211 of the bottle body 21, or the identification information 40 may be directly printed on the side surface 211 of the bottle body 21. The identification information 40 includes, for example, identification information regarding the liquid reagent filled in the reagent bottle 20.
　試薬ボトル２０の口部２２は筒形状を有しており、口部２２の下端がボトル本体２１に連設されている。口部２２の上端は開口端となっており、開口部２２１が形成されている。試薬ボトル２０におけるボトル本体２１は、口部２２に形成された開口部２２１を通じて内部に充填された液状の試薬を貯留することができる。また、口部２２の外周面２２ａには、試薬ボトル用キャップ３０を取り付けるための外ネジ２２２が形成されている。 The mouth 22 of the reagent bottle 20 has a cylindrical shape, and the lower end of the mouth 22 is connected to the bottle body 21. The upper end of the mouth 22 is an open end, and an opening 221 is formed. The bottle body 21 of the reagent bottle 20 can store the liquid reagent filled therein through the opening 221 formed in the mouth 22. Further, an outer screw 222 for attaching the reagent bottle cap 30 is formed on the outer peripheral surface 22 a of the mouth portion 22.
　次に、試薬ボトル用キャップ３０について説明する。試薬ボトル用キャップ３０は、ボトル本体２１の口部２２に固着されるアタッチメント部３１と、当該アタッチメント部３１に対して回動自在に取り付けられる開閉キャップ部３２とから構成されている。試薬ボトル用キャップ３０は、例えば樹脂を成形することで作製することができる。 Next, the reagent bottle cap 30 will be described. The reagent bottle cap 30 includes an attachment portion 31 fixed to the mouth portion 22 of the bottle body 21, and an opening / closing cap portion 32 rotatably attached to the attachment portion 31. The reagent bottle cap 30 can be manufactured, for example, by molding a resin.
　図３及び図４は、試薬ボトル用キャップ３０の分解図である。図３は、試薬ボトル用キャップ３０のアタッチメント部３１を示す図である。図４は、試薬ボトル用キャップ３０の開閉キャップ部３２を示す図である。 3 and 4 are exploded views of the reagent bottle cap 30. FIG. 3 is a view showing the attachment part 31 of the reagent bottle cap 30. FIG. 4 is a view showing the opening / closing cap portion 32 of the reagent bottle cap 30.
　アタッチメント部３１は、試薬ボトル２０の口部２２の周囲に外嵌されると共に口部２２に固着される固着部３１１を有する。固着部３１１は、口部２２の外径と略等しい内径を有する内周面を有しており、この内周面には、試薬ボトル２０における口部２２の外周面２２ａに形成された外ネジ２２２と螺合可能なネジ溝（図示せず）が形成されている。アタッチメント部３１と試薬ボトル２０の口部２２のアタッチメントの方法としては、当業者であれば、適宜選択して、好適な固着部の構造を設計することができ、例えば、ネジ式やそのまま押し込む方式等が挙げられる。また、アタッチメント部３１やキャップ本体の大きさは、当業者であれば、適宜設計することができるが、アタッチメント部３１における固着部３１１の大きさは口部２２の径に応じて設計し、後述する装着部３１２の大きさは、所定の規格のキャップ本体３２１に対してその側壁部３２４の内周面側の径に応じて設計することが好ましい。適したアタッチメントを用意することで、安価で容易に様々な試薬ボトル２０や様々な規格のキャップ本体３２１間で生じる課題を解決することができる。 The attachment part 31 has a fixing part 311 which is fitted around the mouth part 22 of the reagent bottle 20 and fixed to the mouth part 22. The fixed portion 311 has an inner peripheral surface having an inner diameter substantially equal to the outer diameter of the mouth portion 22, and the inner peripheral surface has an outer screw formed on the outer peripheral surface 22a of the mouth portion 22 of the reagent bottle 20. A thread groove (not shown) that can be screwed into 222 is formed. As a method of attaching the attachment part 31 and the mouth part 22 of the reagent bottle 20, those skilled in the art can appropriately select and design a suitable structure of the fixing part, for example, a screw type or a pressing type as it is. Etc. The size of the attachment part 31 and the cap body can be appropriately designed by those skilled in the art, but the size of the fixing part 311 in the attachment part 31 is designed according to the diameter of the mouth part 22, and will be described later. The size of the mounting portion 312 to be mounted is preferably designed according to the diameter of the side wall portion 324 of the cap body 321 of a predetermined standard on the inner peripheral surface side. By preparing a suitable attachment, it is possible to easily and inexpensively solve the problem that occurs between various reagent bottles 20 and cap bodies 321 of various standards.
　また、図３に示すアタッチメント部３１は、固着部３１１の上部に装着部３１２が設けられている。アタッチメント部３１の装着部３１２の外周面３１２ａには、開閉キャップ部３２を回動自在に装着するための係合突起３１３が、装着部３１２の外周面３１２ａの周方向全周に亘って形成されている。 Also, in the attachment part 31 shown in FIG. 3, a mounting part 312 is provided above the fixing part 311. Engagement protrusions 313 for rotatably mounting the opening / closing cap portion 32 are formed on the outer peripheral surface 312a of the mounting portion 312 of the attachment portion 31 over the entire circumference of the outer peripheral surface 312a of the mounting portion 312. ing.
　次に、図４を参照して開閉キャップ部３２について説明する。開閉キャップ部３２は、アタッチメント部３１に回動自在に装着されるキャップ本体３２１と、試薬ボトル２０における口部２２の開口部２２１を開閉自在な蓋体３２２を有している。開閉キャップ部３２におけるキャップ本体３２１と蓋体３２２は、ヒンジ３２３を介して連結されている。 Next, the opening / closing cap portion 32 will be described with reference to FIG. The open / close cap unit 32 includes a cap body 321 that is rotatably attached to the attachment unit 31, and a lid 322 that can open and close the opening 221 of the mouth 22 of the reagent bottle 20. The cap body 321 and the lid 322 in the open / close cap unit 32 are connected via a hinge 323.
　キャップ本体３２１は有頂円筒形状を有する部材であり、円筒状の側壁部３２４と、当該側壁部３２４の上端に連なる頂壁部３２５を含んでいる。頂壁部３２５の中央側には、キャップ開口部３２６が形成されている。本実施形態におけるキャップ開口部３２６は、円形断面を有しているが、他の形状を有していてもよい。また、キャップ本体３２１における側壁部３２４の内周面側には、アタッチメント部３１の装着部３１２における係合突起３１３と係合する係合部３２７が設けられている。キャップ本体３２１の係合部３２７とアタッチメント部３１の装着部３１２における係合突起３１３が係合することで、アタッチメント部３１とキャップ本体３２１の相対回動を自在としつつ、アタッチメント部３１に対してキャップ本体３２１が外れることが抑制される。 The cap body 321 is a member having a topped cylindrical shape, and includes a cylindrical side wall portion 324 and a top wall portion 325 that is continuous with the upper end of the side wall portion 324. A cap opening 326 is formed on the center side of the top wall 325. The cap opening 326 in this embodiment has a circular cross section, but may have another shape. Further, on the inner peripheral surface side of the side wall portion 324 of the cap body 321, an engaging portion 327 that engages with the engaging protrusion 313 of the mounting portion 312 of the attachment portion 31 is provided. The engagement portion 327 of the cap body 321 and the engagement protrusion 313 of the mounting portion 312 of the attachment portion 31 are engaged with each other, so that the attachment portion 31 and the cap body 321 can rotate relative to each other, and the attachment portion 31 can be rotated. The cap body 321 is prevented from coming off.
　例えば、キャップ本体３２１における係合部３２７は、アタッチメント部３１の係合突起３１３を遊嵌可能な嵌合溝であってもよい。なお、アタッチメント部３１及びキャップ本体３２１が相対回動する際の回動軸は、試薬ボトル２０の口部２２の中心軸と同軸になっており、且つ、ボトル本体２１の底部と直交している。なお、本実施形態において、キャップ本体３２１における係合部３２７は、側壁部３２４の周方向に沿って複数箇所に設けられている。図４に示す例では、キャップ本体３２１における係合部３２７が、側壁部３２４の周方向に沿って９０°ずつ回転した箇所、合計で４箇所に配置されているが、これには限定されない。 For example, the engaging portion 327 of the cap body 321 may be a fitting groove into which the engaging protrusion 313 of the attachment portion 31 can be loosely fitted. The rotation axis when the attachment part 31 and the cap body 321 rotate relative to each other is coaxial with the central axis of the mouth 22 of the reagent bottle 20 and orthogonal to the bottom of the bottle body 21. . In the present embodiment, the engaging portions 327 of the cap body 321 are provided at a plurality of locations along the circumferential direction of the side wall portion 324. In the example shown in FIG. 4, the engaging portions 327 of the cap body 321 are arranged at a total of four locations, which are rotated by 90 ° along the circumferential direction of the side wall portion 324, but are not limited to this.
　更に、本実施形態におけるキャップ本体３２１の側壁部３２４には、試薬ボトル２０の設置対象物に設けられた係合部材と係合可能な被係合部３２８が設けられている。ここで、被係合部３２８は、図４に示すように側壁部３２４の外面から側方に突設された支持片３２９と、この支持片３２９に支持される円筒スリーブ３３０を有している。円筒スリーブ３３０の中心軸は、キャップ本体３２１の側壁部３２４の中心軸ＣＬと平行である。 Further, the side wall portion 324 of the cap body 321 in the present embodiment is provided with an engaged portion 328 that can engage with an engaging member provided on the installation object of the reagent bottle 20. Here, the engaged portion 328 has a support piece 329 protruding laterally from the outer surface of the side wall portion 324 and a cylindrical sleeve 330 supported by the support piece 329, as shown in FIG. . The central axis of the cylindrical sleeve 330 is parallel to the central axis CL of the side wall portion 324 of the cap body 321.
　次に、試薬ボトル用キャップ３０の蓋体３２２について説明する。試薬ボトル用キャップ３０の蓋体３２２は、ヒンジ３２３を介してキャップ本体３２１に対して回動自在に連結されている。ヒンジ３２３のヒンジ軸は、キャップ本体３２１の側壁部３２４の中心軸と直交している。また、図４に示すように、キャップ本体３２１においては、ヒンジ３２３と被係合部３２８が、キャップ本体３２１の中心軸ＣＬに対して対称な位置（中心軸周りに１８０°ずれた位置）に配置されている。 Next, the lid 322 of the reagent bottle cap 30 will be described. The lid 322 of the reagent bottle cap 30 is rotatably connected to the cap body 321 via a hinge 323. The hinge axis of the hinge 323 is orthogonal to the central axis of the side wall portion 324 of the cap body 321. Further, as shown in FIG. 4, in the cap body 321, the hinge 323 and the engaged portion 328 are located at positions symmetrical with respect to the central axis CL of the cap body 321 (positions shifted by 180 ° around the central axis). It is arranged.
　蓋体３２２は、ヒンジ３２３を介して回動することで、キャップ本体３２１の頂壁部３２５に覆い被せられることで頂壁部３２５のキャップ開口部３２６を閉鎖する閉蓋姿勢（図５を参照）と、キャップ本体３２１の頂壁部３２５から離脱することでキャップ開口部３２６を開放する開蓋姿勢（図１、図４等を参照）とに切り替えることで、キャップ開口部３２６を開閉することができる。図５は、蓋体３２２が閉蓋姿勢にある試薬容器１０の一部を示す図である。 The lid body 322 is rotated via a hinge 323 to cover the top wall portion 325 of the cap body 321 to close the cap opening 326 of the top wall portion 325 (see FIG. 5). ) And the lid opening posture (see FIG. 1, FIG. 4, etc.) in which the cap opening 326 is opened by detaching it from the top wall 325 of the cap body 321 to open and close the cap opening 326. You can FIG. 5 is a diagram showing a part of the reagent container 10 in which the lid 322 is in the closed posture.
　蓋体３２２の下面３２２ａには、閉蓋姿勢の状態でキャップ開口部３２６に挿入されることでキャップ開口部３２６を封止するための封止部材３３１が、下面３２２ａから下方に向けて突設されている。封止部材３３１は円筒形状を有し、その外径はキャップ開口部３２６の直径に等しくなっている。なお、封止部材３３１は、蓋体３２２が閉じられる際にキャップ開口部３２６を封止し、また、繰り返し開閉動作をスムーズ行うことができればよく、キャップ開口部３２６の形状、大きさ等に応じて種々の形態を採用することができる。 A sealing member 331 for sealing the cap opening 326 by being inserted into the cap opening 326 in the closed posture is provided on the lower surface 322a of the lid 322 so as to protrude downward from the lower surface 322a. Has been done. The sealing member 331 has a cylindrical shape, and its outer diameter is equal to the diameter of the cap opening 326. Note that the sealing member 331 may seal the cap opening 326 when the lid 322 is closed, and can smoothly perform repeated opening / closing operations, depending on the shape, size, or the like of the cap opening 326. Various forms can be adopted.
　また、蓋体３２２における上面３２２ｂには、上方に向けて開蓋操作用凸部３３２が突設されている。図５に示すように、開蓋操作用凸部３３２は、蓋体３２２における上面３２２ｂから垂直に立設する平板状の突片部材である。開蓋操作用凸部３３２の横幅方向は、ヒンジ３２３のヒンジ軸に平行に延在している。開蓋操作用凸部３３２は、例えば、試薬容器１０を適用する分析装置が備えるキャップ開閉ユニットが試薬ボトル用キャップ３０を開蓋する際に、当該キャップ開閉ユニットによって操作される。 Further, a lid opening operation convex portion 332 is provided on the upper surface 322b of the lid body 322 so as to project upward. As shown in FIG. 5, the lid-opening operation convex portion 332 is a flat plate-like projecting member that stands upright from the upper surface 322b of the lid body 322. The lateral width direction of the lid-opening operation convex portion 332 extends parallel to the hinge axis of the hinge 323. The lid opening operation convex portion 332 is operated by the cap opening / closing unit when the cap opening / closing unit included in the analyzer to which the reagent container 10 is applied opens the reagent bottle cap 30, for example.
＜試薬容器の組み立て＞
　試薬容器１０は、上述した試薬ボトル２０の口部２２に試薬ボトル用キャップ３０を取り付けることで完成する。すなわち、試薬ボトル２０の口部２２にアタッチメント部３１を取り付け、アタッチメント部３１に対して開閉キャップ部３２を相対回動自在に装着する。アタッチメント部３１は、固着部３１１に設けられているネジ溝を口部２２の外周面２２ａに形成された外ネジ２２２に螺着することで、試薬ボトル２０の口部２２に対してアタッチメント部３１を一体に固定することができる。 <Assembly of reagent container>
The reagent container 10 is completed by attaching the reagent bottle cap 30 to the mouth portion 22 of the reagent bottle 20 described above. That is, the attachment portion 31 is attached to the mouth portion 22 of the reagent bottle 20, and the opening / closing cap portion 32 is attached to the attachment portion 31 so as to be rotatable relative to each other. The attachment part 31 is attached to the mouth part 22 of the reagent bottle 20 by screwing a screw groove provided in the fixing part 311 onto an outer screw 222 formed on the outer peripheral surface 22 a of the mouth part 22. Can be fixed together.
　そして、試薬ボトル２０の口部２２に固着されたアタッチメント部３１に対して試薬ボトル用キャップ３０を上方から嵌め込み、アタッチメント部３１の装着部３１２における係合突起３１３に対してキャップ本体３２１における側壁部３２４の係合部３２７を係合させる。その結果、アタッチメント部３１に対して開閉キャップ部３２を相対回動自在に装着することができ、図１に示すような試薬容器１０が完成する。 Then, the reagent bottle cap 30 is fitted into the attachment portion 31 fixed to the mouth portion 22 of the reagent bottle 20 from above, and the side wall portion of the cap body 321 is fitted to the engaging protrusion 313 of the mounting portion 312 of the attachment portion 31. The engaging portion 327 of 324 is engaged. As a result, the opening / closing cap portion 32 can be attached to the attachment portion 31 so as to be rotatable relative to each other, and the reagent container 10 as shown in FIG. 1 is completed.
　ここで、試薬容器１０が完成した状態において、試薬ボトル２０の口部２２の開口部２２１は、開閉キャップ部３２におけるキャップ開口部３２６と連通している。そして、開閉キャップ部３２における蓋体３２２が閉蓋姿勢になることで、蓋体３２２の封止部材３３１によってキャップ開口部３２６が封止される結果、試薬容器１０（試薬ボトル２０）を密封することができる。これにより、試薬ボトル２０内の試薬が蒸発することを防ぎ、空気との接触に起因して変質することを抑制することができる。また、予期せぬ異物の混入を防止することもできる。 Here, when the reagent container 10 is completed, the opening 221 of the mouth 22 of the reagent bottle 20 communicates with the cap opening 326 of the opening / closing cap 32. When the lid 322 of the open / close cap unit 32 is in the closed posture, the cap opening 326 is sealed by the sealing member 331 of the lid 322. As a result, the reagent container 10 (reagent bottle 20) is sealed. be able to. Thereby, the reagent in the reagent bottle 20 can be prevented from evaporating and the deterioration due to the contact with the air can be suppressed. In addition, it is possible to prevent unexpected mixing of foreign matter.
　そして、開閉キャップ部３２におけるヒンジ軸を中心として蓋体３２２を回動させて蓋体３２２を閉蓋姿勢から開蓋姿勢に切り替えることで、試薬ボトル２０の口部２２の開口部２２１及びキャップ開口部３２６が開放される。これにより、例えば、分析装置において生体サンプルが分注されたキュベット等の検体容器に、試薬容器１０内の試薬を分注する際、分析装置の試薬分注ノズルを試薬ボトル２０の口部２２内に挿入して、ボトル内部の試薬を採取することができる。 Then, the lid 322 is rotated about the hinge axis in the opening / closing cap portion 32 to switch the lid 322 from the closed posture to the open posture, whereby the opening 221 of the mouth 22 of the reagent bottle 20 and the cap opening. The part 326 is opened. Thereby, for example, when the reagent in the reagent container 10 is dispensed into a sample container such as a cuvette into which a biological sample is dispensed in the analyzer, the reagent dispensing nozzle of the analyzer is placed in the mouth 22 of the reagent bottle 20. , And the reagent inside the bottle can be collected.
　また、本実施形態における試薬ボトル用キャップ３０によれば、試薬ボトル２０の口部２２に固着されるアタッチメント部３１と、当該アタッチメント部３１に対して回動自在に取り付けられると共に、口部２２を開閉自在な蓋体３２２を有する開閉キャップ部３２を備えているため、試薬ボトル２０の側面２１１に付された識別情報４０（識別情報シール５０）の向きと、試薬ボトル用キャップ３０（開閉キャップ部３２）における被係合部３２８（円筒スリーブ３３０）の向きを任意の関係に調整することができる。 Further, according to the reagent bottle cap 30 in the present embodiment, the attachment portion 31 fixed to the mouth portion 22 of the reagent bottle 20, the attachment portion 31 rotatably attached to the attachment portion 31, and the mouth portion 22 Since the opening / closing cap portion 32 having the lid 322 that can be opened and closed is provided, the orientation of the identification information 40 (identification information seal 50) attached to the side surface 211 of the reagent bottle 20 and the reagent bottle cap 30 (opening / closing cap portion). The direction of the engaged portion 328 (cylindrical sleeve 330) in 32) can be adjusted to any relationship.
＜使用時の動作＞
　試薬容器１０は、例えば、図６に示すような分析装置１０００における所定位置にセットされる。分析装置１０００は、生体サンプル中の成分を分析する装置である。図６に示す符号Ｃは、試薬庫カバーである。ユーザは、試薬庫カバーＣを開くことで、試薬容器１０を試薬庫にセットすることができる。なお、出荷時において試薬ボトル２０に通常のボトル用キャップが取り付けられていた試薬容器を開梱した後、上記ボトル用キャップを本実施形態に係る試薬ボトル用キャップ３０に交換してから分析装置１０００における所定位置にセットしてもよい。或いは、本実施形態における試薬ボトル２０に試薬ボトル用キャップ３０が取り付けられた状態の試薬容器１０の状態で出荷されてもよい。 <Operation during use>
The reagent container 10 is set at a predetermined position in the analyzer 1000 as shown in FIG. 6, for example. The analysis device 1000 is a device that analyzes components in a biological sample. Reference numeral C shown in FIG. 6 is a reagent storage cover. The user can set the reagent container 10 in the reagent container by opening the reagent container cover C. In addition, after unpacking the reagent container in which the normal bottle cap is attached to the reagent bottle 20 at the time of shipment, the bottle cap is replaced with the reagent bottle cap 30 according to the present embodiment, and then the analyzer 1000. It may be set at a predetermined position in. Alternatively, the reagent bottle 10 in the present embodiment may be shipped in the state of the reagent container 10 in which the reagent bottle cap 30 is attached.
　図７は、分析装置１０００における試薬庫に設置された試薬テーブル１０４の一部分を示す図である。試薬テーブル１０４は、所定の回転軸を中心に回転するディスク状のテーブルであり、テーブルには、試薬容器１０（試薬ボトル２０）を保持（設置）するための複数のボトル設置部１０４１が環状に配列されている。ボトル設置部１０４１は、試薬容器１０（試薬ボトル２０）の下部側を収容可能な凹部であり、収容された試薬容器１０（試薬ボトル２０）を保持することができる。本実施形態においては、試薬テーブル１０４が試薬ボトルの設置対象物に相当する。 FIG. 7 is a diagram showing a part of the reagent table 104 installed in the reagent storage in the analyzer 1000. The reagent table 104 is a disk-shaped table that rotates about a predetermined rotation axis, and a plurality of bottle installation units 1041 for holding (installing) the reagent container 10 (reagent bottle 20) are annularly formed on the table. It is arranged. The bottle installation unit 1041 is a recess that can accommodate the lower side of the reagent container 10 (reagent bottle 20) and can hold the accommodated reagent container 10 (reagent bottle 20). In the present embodiment, the reagent table 104 corresponds to the installation object of the reagent bottle.
　また、試薬テーブル１０４は、ボトル設置部１０４１の近傍に、鉛直上向きに突設された棒状部材１０４２を備える。棒状部材１０４２は、ボトル設置部１０４１毎に対応して設けられており、対応するボトル設置部１０４１に対して試薬テーブル１０４の回転軸側の位置に配置されている。 Further, the reagent table 104 is provided with a rod-shaped member 1042 protruding vertically upward in the vicinity of the bottle setting unit 1041. The rod-shaped member 1042 is provided corresponding to each bottle installation section 1041, and is arranged at a position on the rotation axis side of the reagent table 104 with respect to the corresponding bottle installation section 1041.
　試薬容器１０（試薬ボトル２０）をボトル設置部１０４１に設置する際、ユーザは、試薬ボトル用キャップ３０（開閉キャップ部３２）における円筒スリーブ３３０（被係合部３２８）に、棒状部材１０４２を上から挿入する。ところで、図７中の白抜き矢印Ｄは、試薬容器１０（試薬ボトル２０）をボトル設置部１０４１に設置する際に、試薬ボトル２０の識別情報４０（識別情報シール５０）を向ける方向を示したものである。この分析装置１０００においては、試薬テーブル１０４の周辺に固定されたバーコードリーダ等の読み取り装置（図示せず）によって、各試薬ボトル２０の識別情報４０を読み取ることが行われる。したがって、図７の矢印Ｄで示されるように、識別情報４０が試薬テーブル１０４の径方向外側に向くように、各ボトル設置部１０４１に試薬ボトル２０をセットする必要がある。 When installing the reagent container 10 (reagent bottle 20) in the bottle installation section 1041, the user places the rod-shaped member 1042 on the cylindrical sleeve 330 (engaged section 328) of the reagent bottle cap 30 (open / close cap section 32). Insert from. By the way, the white arrow D in FIG. 7 indicates the direction in which the identification information 40 (identification information seal 50) of the reagent bottle 20 is directed when the reagent container 10 (reagent bottle 20) is installed in the bottle installation section 1041. It is a thing. In the analyzer 1000, the identification information 40 of each reagent bottle 20 is read by a reading device (not shown) such as a bar code reader fixed around the reagent table 104. Therefore, as shown by the arrow D in FIG. 7, it is necessary to set the reagent bottle 20 in each bottle installation unit 1041 so that the identification information 40 is directed outward in the radial direction of the reagent table 104.
　これに対して、本実施形態における試薬ボトル用キャップ３０によれば、試薬ボトル２０の口部２２に固着されたアタッチメント部３１と円筒スリーブ３３０（被係合部３２８）が設けられる開閉キャップ部３２が回動自在であるため、試薬ボトル２０の側面２１１に付された識別情報４０（識別情報シール５０）の向きと、開閉キャップ部３２における円筒スリーブ３３０（被係合部３２８）の向きを自由に調整することができる。これにより、使用者は、試薬テーブル１０４のボトル設置部１０４１に試薬ボトル２０を設置する際、円筒スリーブ３３０（被係合部３２８）に棒状部材１０４２を挿通させつつ、容易に識別情報４０をバーコードリーダ等の読み取り装置によって読み取り可能な適正方向に好適に向かせることができる。それゆえ、試薬ボトル２０に付された識別情報４０の読み取りエラーが起こることを抑制できる。なお、本実施形態においては、開閉キャップ部３２における円筒スリーブ３３０（被係合部３２８）の向きと、試薬ボトル２０に付された識別情報４０の向きが、試薬ボトル用キャップ側の特定部位の向きと試薬ボトル側の特定部位の向きの組み合わせに相当する。 On the other hand, according to the reagent bottle cap 30 in the present embodiment, the opening / closing cap portion 32 in which the attachment portion 31 fixed to the mouth portion 22 of the reagent bottle 20 and the cylindrical sleeve 330 (engaged portion 328) are provided. Is rotatable, the orientation of the identification information 40 (identification information seal 50) attached to the side surface 211 of the reagent bottle 20 and the orientation of the cylindrical sleeve 330 (engaged portion 328) in the opening / closing cap portion 32 can be freely set. Can be adjusted to. Thereby, when the user installs the reagent bottle 20 in the bottle installation section 1041 of the reagent table 104, the user can easily insert the bar-shaped member 1042 into the cylindrical sleeve 330 (engaged section 328) and display the identification information 40 on the bar. It is possible to properly orient the device in a proper direction that can be read by a reading device such as a code reader. Therefore, the reading error of the identification information 40 attached to the reagent bottle 20 can be suppressed. In the present embodiment, the orientation of the cylindrical sleeve 330 (engaged portion 328) in the opening / closing cap portion 32 and the orientation of the identification information 40 attached to the reagent bottle 20 correspond to the specific portion on the reagent bottle cap side. This corresponds to a combination of the orientation and the orientation of the specific portion on the reagent bottle side.
　なお、図８は、分析装置１０００におけるキャップ開閉ユニット１０５を説明する図である。キャップ開閉ユニット１０５は、ボトル設置部１０４１に設置されている試薬容器１０における試薬ボトル用キャップ３０の蓋体３２２を開閉するためのユニットである。キャップ開閉ユニット１０５は、駆動機構によって、試薬テーブル１０４の径方向に沿った方向への変位と、上下方向への変位が可能な開閉操作用具１０５１を有している。例えば、キャップ開閉ユニット１０５が、対象となる試薬容器１０の蓋体３２２を開閉する際、試薬テーブル１０４を回転させることで試薬容器１０が移動する軌道上に開閉操作用具１０５１を移動させ、回転移動する試薬容器１０の蓋体３２２に開閉操作用具１０５１を衝突（接触）させることで、蓋体３２２を開閉することができる。なお、試薬容器１０の蓋体３２２を開蓋する際には、閉蓋姿勢にある蓋体３２２の開蓋操作用凸部３３２のうち、ヒンジ３２３とは逆方向の面３３２ａ（図５を参照）に開閉操作用具１０５１を衝突させる。これにより、ヒンジ３２３を支点として蓋体３２２が開蓋する開蓋方向に回転モーメントが作用し、蓋体３２２が開蓋される。一方、試薬容器１０の蓋体３２２を閉蓋する際には、上記開蓋時の反対方向に試薬テーブル１０４を回転させると共に開閉操作用具１０５１を蓋体３２２に衝突させる。これにより、閉蓋方向への回転モーメントが蓋体３２２に作用する。また、蓋体３２２の封止部材３３１がキャップ本体３２１におけるキャップ開口部３２６を封止するように蓋体３２２を完全に閉蓋するために、開閉操作用具１０５１の鉛直下方に閉蓋対象の試薬容器１０を移動させた後、キャップ開閉ユニット１０５は開閉操作用具１０５１を鉛直下方に変位させることで、開閉操作用具１０５１によって蓋体３２２の上面３２２ｂを下方のキャップ本体３２１側に押し付けてもよい。これにより、キャップ本体３２１におけるキャップ開口部３２６が封止部材３３１によって封止され、試薬容器１０を密閉状態にすることができる。 Note that FIG. 8 is a diagram for explaining the cap opening / closing unit 105 in the analyzer 1000. The cap opening / closing unit 105 is a unit for opening / closing the lid 322 of the reagent bottle cap 30 in the reagent container 10 installed in the bottle installation unit 1041. The cap opening / closing unit 105 has an opening / closing operation tool 1051 which can be displaced in the radial direction of the reagent table 104 and vertically displaced by a drive mechanism. For example, when the cap opening / closing unit 105 opens / closes the lid 322 of the target reagent container 10, the reagent table 104 is rotated to move the opening / closing operation tool 1051 on the orbit along which the reagent container 10 moves, and rotationally moves. The lid 322 can be opened and closed by colliding (contacting) the opening / closing operation tool 1051 with the lid 322 of the reagent container 10. When the lid 322 of the reagent container 10 is opened, a surface 332a of the lid-opening operation convex portion 332 of the lid 322 in the closed posture in the direction opposite to the hinge 323 (see FIG. 5). ), The opening / closing operation tool 1051 is made to collide. As a result, a rotation moment acts on the hinge 323 as a fulcrum in the opening direction in which the lid 322 opens, and the lid 322 is opened. On the other hand, when the lid 322 of the reagent container 10 is closed, the reagent table 104 is rotated in the opposite direction to the opening of the reagent container 10 and the opening / closing operation tool 1051 is collided with the lid 322. As a result, a rotational moment in the closing direction acts on the lid body 322. Further, in order to completely close the lid 322 so that the sealing member 331 of the lid 322 seals the cap opening 326 in the cap body 321, the reagent to be closed vertically below the opening / closing operation tool 1051. After moving the container 10, the cap opening / closing unit 105 may vertically displace the opening / closing operation tool 1051 so that the opening / closing operation tool 1051 presses the upper surface 322b of the lid 322 toward the lower cap body 321 side. As a result, the cap opening 326 of the cap body 321 is sealed by the sealing member 331, and the reagent container 10 can be sealed.
１０・・・試薬容器
２０・・・試薬ボトル
２１・・・ボトル本体
２２・・・口部
３０・・・試薬ボトル用キャップ
３１・・・アタッチメント部
３２・・・開閉キャップ部
４０・・・識別情報
５０・・・識別情報シール
３２１・・・キャップ本体
３２２・・・蓋体 10 ... Reagent container 20 ... Reagent bottle 21 ... Bottle body 22 ... Mouth portion 30 ... Reagent bottle cap 31 ... Attachment portion 32 ... Opening / closing cap portion 40 ... Identification Information 50 ... Identification information seal 321 ... Cap body 322 ... Lid

Claims (6)

  1. 　試薬ボトルの口部に固着されるアタッチメント部と、
    　前記アタッチメント部に対して回動自在に取り付けられると共に、前記口部を開閉自在
    な蓋体を有する開閉キャップ部と、
    　を備える、
    　試薬ボトル用キャップ。     An attachment part fixed to the mouth of the reagent bottle,
    An opening / closing cap part that is rotatably attached to the attachment part and has a lid body that can open and close the mouth part,
    Comprising,
    Reagent bottle cap.
  2. 　前記開閉キャップ部に、前記試薬ボトルの設置対象物に設けられた係合部材と係合可能な被係合部が設けられている、
    　請求項１に記載の試薬ボトル用キャップ。     The opening / closing cap portion is provided with an engaged portion that is engageable with an engaging member provided on the installation object of the reagent bottle,
    The cap for reagent bottles according to claim 1.
  3. 　前記設置対象物は、生体サンプル中の成分を分析する分析装置の試薬テーブルであり、
    　前記係合部材は、前記試薬テーブルに形成されたボトル設置部の近傍において当該試薬テーブルから上方に向けて突設された棒状部材であり、
    　前記被係合部は、前記軸部材を挿通可能な筒部を有している、
    　請求項２に記載の試薬ボトル用キャップ。     The installation target is a reagent table of an analyzer for analyzing components in a biological sample,
    The engagement member is a rod-shaped member that is provided so as to project upward from the reagent table in the vicinity of the bottle installation portion formed on the reagent table,
    The engaged portion has a tubular portion through which the shaft member can be inserted.
    The reagent bottle cap according to claim 2.
  4. 　前記アタッチメント部は、前記口部に形成されたネジ部に螺着される、
    　請求項１から３の何れか一項に記載の試薬ボトル用キャップ。     The attachment part is screwed to a screw part formed in the mouth part,
    The reagent bottle cap according to any one of claims 1 to 3.
  5. 　請求項１から４の何れか一項に記載の試薬ボトル用キャップと、
    　前記試薬ボトル用キャップにおける前記アタッチメント部が固着される口部、及び内部に試薬を充填可能なボトル本体を有する試薬ボトルと、
    　を備える試薬容器。     A reagent bottle cap according to any one of claims 1 to 4,
    A mouthpiece to which the attachment portion is fixed in the reagent bottle cap, and a reagent bottle having a bottle body capable of filling a reagent therein,
    A reagent container provided with.
  6. 　前記ボトル本体の側面に、試薬に関する識別情報が付されている、
    　請求項５に記載の試薬容器。     Identification information about the reagent is attached to the side surface of the bottle body,
    The reagent container according to claim 5.
PCT/JP2019/040045 2018-10-10 2019-10-10 Reagent bottle cap and reagent container WO2020075811A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2020551227A JPWO2020075811A1 (en) 2018-10-10 2019-10-10 Reagent bottle caps and reagent containers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018192185 2018-10-10
JP2018-192185 2018-10-10

Publications (1)

Publication Number Publication Date
WO2020075811A1 true WO2020075811A1 (en) 2020-04-16

Family

ID=70164577

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2019/040045 WO2020075811A1 (en) 2018-10-10 2019-10-10 Reagent bottle cap and reagent container

Country Status (2)

Country Link
JP (1) JPWO2020075811A1 (en)
WO (1) WO2020075811A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05294354A (en) * 1991-11-19 1993-11-09 Syntex Usa Inc Closure
JP2009098114A (en) * 2007-09-25 2009-05-07 Fujifilm Corp Reagent container
JP2009184709A (en) * 2008-02-07 2009-08-20 Takeuchi Press Ind Co Ltd Container with hinged cap

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05294354A (en) * 1991-11-19 1993-11-09 Syntex Usa Inc Closure
JP2009098114A (en) * 2007-09-25 2009-05-07 Fujifilm Corp Reagent container
JP2009184709A (en) * 2008-02-07 2009-08-20 Takeuchi Press Ind Co Ltd Container with hinged cap

Also Published As

Publication number Publication date
JPWO2020075811A1 (en) 2021-09-02

Similar Documents

Publication Publication Date Title
US8529847B2 (en) Reagent kit for analyzing apparatus
US7897123B2 (en) Reagent vessel cap and method for collecting reagent
US4805772A (en) Adaptors for use with various containers bearing bar code labeling
ES2324471T3 (en) AUTOMATIC ANALYZER.
US7799284B2 (en) Sample container
US7988933B2 (en) Identification system for a clinical sample container
JPH05294354A (en) Closure
EP3057695B1 (en) Paint storage and mixing system
JP5621034B2 (en) Reagent kit with fixing means during transportation
US5859703A (en) Spectrophotometric analysis
JP6336791B2 (en) Closed system for reagent container receiving position in automatic analyzer
JP2013524190A5 (en)
AU2004203342B2 (en) Container closure and device to install and remove closure
US20220373569A1 (en) Automated reagent identification for fluid handling system
JP7080391B2 (en) Automatic analyzer
WO2020075811A1 (en) Reagent bottle cap and reagent container
JP2006027704A (en) Closure of container, and device for mounting and removing the closure
JP2007047048A (en) Sealing member and cap of reagent container using the same
JP2018059801A (en) Automatic analyzer
JPH10311835A (en) Reagent stocker of automatic analyzer
JP2008180638A (en) Automatic analyzer
WO2020044005A1 (en) Apparatus for testing a liquid specimen
JP4474260B2 (en) Automatic analyzer proportionality confirmation reagent kit
JP6180763B2 (en) Automatic analyzer
JP2019138729A (en) Autoanalyzer and reagent container

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19871656

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2020551227

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19871656

Country of ref document: EP

Kind code of ref document: A1