WO2020052122A1 - 一种主动自锁式注射器 - Google Patents

一种主动自锁式注射器 Download PDF

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Publication number
WO2020052122A1
WO2020052122A1 PCT/CN2018/120170 CN2018120170W WO2020052122A1 WO 2020052122 A1 WO2020052122 A1 WO 2020052122A1 CN 2018120170 W CN2018120170 W CN 2018120170W WO 2020052122 A1 WO2020052122 A1 WO 2020052122A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle tip
syringe
trigger
needle
wall
Prior art date
Application number
PCT/CN2018/120170
Other languages
English (en)
French (fr)
Inventor
胡超宇
Original Assignee
普昂(杭州)医疗科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 普昂(杭州)医疗科技有限公司 filed Critical 普昂(杭州)医疗科技有限公司
Priority to US16/954,454 priority Critical patent/US11338097B2/en
Publication of WO2020052122A1 publication Critical patent/WO2020052122A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3213—Caps placed axially onto the needle, e.g. equipped with finger protection guards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3271—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position

Definitions

  • the invention relates to the field of safety syringes, and in particular to an active self-locking syringe.
  • a needle-retracting safety syringe After the injection is completed, the needle can be automatically or manually retracted into the syringe or the needle protective sleeve. In order to avoid the risk of stabbing the user with the needle tip after use.
  • Another technical route is a trigger safety syringe, that is, the needle tip is fixed relative to the syringe.
  • a triggerable needle tip protection device is provided outside the syringe. During the injection process, the syringe moves axially relative to the needle tip protection device. When the injection is completed, the syringe or piston rod triggers the needle tip protection device. After the needle tip protection device is triggered, it is enough to cover the injection needle to prevent the needle tip from being exposed.
  • the safety syringe based on the above two technical routes has a complicated structure and high production cost. Therefore, it is necessary to develop a new safety syringe to solve the defects of the existing technology.
  • the technical problem to be solved by the present invention is to provide an active self-locking syringe with an improved structure.
  • the active self-locking syringe is triggered by the inside of the syringe to realize a technology with simple structure, lower cost and higher reliability. effect.
  • An active self-locking syringe includes at least:
  • a needle seat which is fixed in a position near the patient end in the syringe, and a spring cavity near the patient end and a trigger cavity near the piston assembly are formed between the outer wall of the needle holder and the inner wall of the syringe;
  • An injection needle the injection needle is fixed on the needle seat and the needle tip extends from the patient end of the syringe;
  • a spring which is located in a spring cavity, and an end of the spring near the needle tip is in contact with the needle tip protective sleeve;
  • a guide limit component which is used to limit the direction and limit position of the axial movement of the needle tip protective sleeve relative to the syringe after the trigger;
  • An initial engagement component which is used to maintain the needle tip guard in a non-triggering state and is provided with a trigger portion that triggers from the trigger cavity to disengage the initial engagement components from each other;
  • the trigger ring plug is located in the trigger cavity and in the initial state, the trigger ring plug does not contact or touch the trigger part but is not enough to disengage the initial engaging component from each other.
  • the inner wall of the trigger ring plug and the Between the outer wall of the trigger ring plug and the inner wall of the syringe.
  • a preferred embodiment further includes a non-return member for preventing the needle tip protective sleeve from retracting in a protected state.
  • the check member includes a check arm provided on a patient end of the syringe, the check arm has elasticity, and a free end of the check arm protrudes from an outer wall of the syringe in a radial direction.
  • a side wall of the needle tip protective sleeve near the patient end is provided with a slot through the side wall, and the slot is used to accommodate the extension of the check arm.
  • the piston assembly includes a piston rod and a piston provided at an end portion of the piston rod, and the end portion of the piston rod is a pushing portion for pushing a trigger ring plug.
  • a matching mechanism is provided between an end of the needle seat far from the patient end and an end of the piston rod near the needle seat.
  • the guide limit assembly includes a convex post provided on an outer wall of the syringe and a guide limit groove provided on a side wall of the needle tip protective sleeve, and the convex post is adapted to the guide limit groove.
  • the initial engaging component includes an elastic arm provided on the needle tip protective sleeve and an engaging groove penetrating the outer wall of the syringe barrel, and a free end of the elastic arm is provided radially inside the needle tip protective sleeve.
  • the extended clamping block is engaged with the clamping end of the engaging groove near the patient end.
  • the triggering portion includes a triggering arm connected to a side of the engaging groove away from the latching end, and the triggering arm has elasticity. In an initial state, a free end of the triggering arm is located in a radial direction of the latching block. Direction inside.
  • the free end of the elastic arm and the free end of the check arm are in conflict with each other under a needle tip protection state.
  • the free end of the elastic arm is lower than the end face of the needle tip protective sleeve in the axial direction.
  • a preferred embodiment further includes a needlepoint protective cap sleeved on the outside of the needlepoint protective sleeve, and the needlepoint protective cap covers the free end of the elastic wall in an initial state.
  • a preferred embodiment further includes a piston rod cover connected to an end of the syringe far from the patient end.
  • a trigger ring stopper provided in the trigger cavity is used to trigger and release the needle tip protective sleeve from the inside of the syringe near the patient end, so as to achieve the technical purpose of preventing the needle tip from being exposed and self-locking.
  • the design is clever, and there are no other auxiliary triggering components outside the syringe and needle tip protective sleeve. It has the technical advantages of simple structure, small radial size of the syringe, simple components, and low production cost.
  • FIG. 1 is a schematic diagram showing the external structure of the active self-locking syringe of this embodiment
  • FIG. 2 is a schematic structural diagram of an explosion state of the active self-locking syringe of this embodiment
  • FIG. 3 is a partial cross-sectional view of the active self-locking syringe of this embodiment in an initial state (not triggered);
  • FIG. 4 is a partial cross-sectional view of a syringe in an active self-locking syringe of this embodiment
  • FIG. 5 is a partial cross-sectional view of the active self-locking syringe of the embodiment under a needle tip protection state
  • FIG. 6 is a schematic structural diagram of the active self-locking syringe of this embodiment in an unused state.
  • an active self-locking syringe in this embodiment includes a syringe 10, a piston assembly, an injection needle 60, a needle tip guard 30, a spring 70, and a needle tip guard 40.
  • one end of the injection needle of the active self-locking syringe is defined as the patient end.
  • the piston assembly is assembled in a syringe, and its structure is shown in FIG. 2 and FIG. 3, and includes a piston rod 20 and a piston 23.
  • the piston rod 20 is provided with a piston ring groove 22 at one end near the patient end.
  • a piston 23 is sleeved in the ring groove 22, wherein the piston 23 and the piston rod 20 are pistons and piston rods commonly used in the prior art.
  • the piston 23 is made of a flexible material.
  • the piston 23 and the piston ring groove 22 are sealed.
  • the piston 23 is sealed with the inner wall of the syringe 10, and the inhalation and injection of the medicinal liquid is realized by pushing and pulling of the piston assembly.
  • an end portion of the piston rod 20 is provided with a pushing portion 21, and the role of the pushing portion 21 is to push the trigger ring 50 to move axially.
  • the end faces are adapted.
  • the needle base 16 is fixed in the syringe 10 near the patient end
  • the injection needle 60 is fixed on the needle base 16 and the needle tip protrudes from the patient end of the syringe 10.
  • the outer wall of the needle seat 16 and the inner wall of the syringe are fixedly connected, and a spring cavity 17 near the patient end side and a trigger cavity 18 near the piston assembly side are formed.
  • a matching fitting mechanism is provided between the end of the needle seat 16 remote from the patient end and the end of the piston rod 20 near the needle seat to reduce the injection process. Residual amount of traditional Chinese medicine liquid.
  • the fitting mechanism includes an outer tapered surface 19 provided at the end of the needle seat and a tapered groove 24 located at the end of the piston rod.
  • the tapered groove can also be provided at the end of the needle seat, and the outer tapered surface is provided at the end of the piston rod.
  • the outer tapered surface and the tapered groove may also be an outer arc surface and a curved groove.
  • a trigger ring plug 50 is installed in the trigger cavity 18, and the inner wall of the trigger ring plug 50 and the outer wall of the needle seat 16 are sealed.
  • the outer wall of the trigger ring plug 50 and the inner wall of the syringe are sealed. Sealed.
  • the trigger ring plug 50 can move axially in the trigger cavity, and the movement of the trigger ring plug 50 is achieved by the pushing of the pushing portion 21.
  • the needle tip guard 30 is used to cover the used injection needle 60.
  • the needle tip guard 30 is sleeved on the patient end of the syringe in an initial state.
  • a spring 70 is provided between the needle tip protective sleeve 30 and the needle cylinder.
  • the spring 70 is located in the spring cavity 17, and an end of the spring near the needle tip contacts the needle tip protective sleeve.
  • the spring 70 is in a compressed energy storage state, and provides a pre-elastic force for the ejection of the needle tip protective sleeve.
  • an initial engagement component is provided between the needle tip protective sleeve 30 and the syringe 10 to maintain the needle tip protective sleeve 30 in a non-triggering state.
  • a preferred initial engagement component in this embodiment includes an elastic arm 32 provided on the needle tip protective sleeve and an engagement groove 12 penetrating the outer wall of the syringe. The free end of the elastic arm 32 is provided.
  • the engaging groove 12 is located on the outer wall of the syringe where the triggering cavity 18 is located, and the initial engaging component further includes a triggering part that triggers from the triggering cavity 18 to disengage the initial engaging components from each other.
  • the triggering portion includes a triggering arm 14 connected to a side of the engaging groove away from the carding end.
  • the triggering arm 14 has elasticity. In an initial state, as shown in FIG. 3, the free end of the triggering arm 14 is located on the card. Radial inside of the adapter.
  • a guide limiting component is provided between the needle tip protective sleeve 30 and the syringe 10, and the guiding limiting component is used to limit the needle tip protective sleeve 30 relative to the syringe after the trigger.
  • the guiding limiting component is used to limit the needle tip protective sleeve 30 relative to the syringe after the trigger.
  • the guide limit assembly in this embodiment includes a convex post 11 provided on an outer wall of the syringe and a guide limit groove 31 provided on a side wall of the needle tip protective sleeve, wherein the convex post is adapted to the guide limit groove, It is used to restrict the relative rotation between the needle tip protective sleeve 30 and the syringe 10, and can only move in the axial direction, and the end of the guide limit slot 31 limits the limit position of the needle tip protective sleeve 30 in the axial movement.
  • the trigger ring plug 50 of the active self-locking syringe of this embodiment is located in the trigger cavity 18, and in the initial state, the trigger ring plug and the trigger portion are not in contact or contact but are not enough to disengage the initial engaging components from each other.
  • the piston assembly is moved to the end far from the needle tip, and the medical fluid is sucked into the syringe.
  • the piston assembly moves toward one end of the needle tip.
  • the pushing portion 21 first contacts the trigger ring plug 50 and continues to push the trigger ring plug 50 to move axially after the contact.
  • the trigger arm 14 is driven to gradually expand outward, and the trigger arm 14 drives the latching block 33 to gradually deform outward in the radial direction, so that the latching block 33 is separated from the latching end 13.
  • the latching block 33 and the latching end 13 are completely separated when the injection of the medicinal solution is completed.
  • the patient end of the needle tip protective sleeve 30 is in contact with the patient's skin.
  • the potential energy stored in the spring 70 is released, which drives the needle tip guard 30 to cover the used injection needle, preventing the injection needle from injuring people and achieving self-locking.
  • a non-return member for preventing the needle tip protective sleeve from retracting in a protected state is further included.
  • the check member of this embodiment includes a check arm 15 provided on the patient end of the syringe.
  • the non-return arm 15 has elasticity, and the free end of the non-return arm 15 protrudes from the outer wall of the syringe in a radial direction.
  • the free end of the elastic arm 32 and the free end of the check arm 15 are in contact with each other to realize self-locking in the state of needle tip protection. Since the non-return arm 15 protrudes from the outer wall of the syringe in the radial direction, the outer diameter of the free end of the non-return arm 15 is larger than the outer diameter of the free end of the elastic arm 32, thereby preventing the needle tip guard from retracting. The non-return part makes the protection reliability better.
  • a side wall of the needle tip protective sleeve 30 near the patient end is provided with a slot 34 through the side wall, which is used to accommodate the extension of the check arm in the initial state.
  • the outer wall of the needle tip protective sleeve is provided with a through groove 36, and the elastic arm 32 is located in the through groove 36.
  • the free end of the elastic arm 32 may be higher or lower than the end surface of the needle tip guard 30 in the axial direction, and may also be flush with the end surface of the needle tip guard 30.
  • the free end of the elastic arm 32 is lower than the end face of the needle tip guard 30 in the axial direction. The purpose of this setting is to reduce the stroke of the needle tip guard and ensure that the spring force of the spring ejects the needle tip guard into place.
  • the active self-locking syringe of this embodiment is further provided with a piston rod cover 80, which is sleeved on the needle in an initial unused state.
  • the end of the barrel far from the patient end is used to prevent the piston rod from being pushed and to avoid accidentally triggering the needle tip protective sleeve.
  • the needle tip protective cap 40 is sleeved on the needle tip protective sleeve 30.
  • the needle tip protective sleeve is also provided with an end connected with the needle tip protective cap. ⁇ joining the step surface 35.
  • the needlepoint protective cap when installed on the needlepoint protective sleeve, it covers the free end of the elastic arm 32. The purpose of this setting is that even if the piston rod is pushed, because the elastic arm 32 is pressed and has no deformation space, the trigger ring plug cannot enter the trigger space inside the trigger arm, and the needle tip guard can also be prevented from being triggered by mistake.
  • the number of the guide limiting component, the initial engaging component, and the non-return component are two groups, and they are evenly arranged along the circumferential direction.
  • the number of the guide limit assembly, the initial engagement assembly and the non-return part can be one or more than three, and in the case of three or more, they are distributed along the circumference, preferably along the circumference. Evenly distributed in the circumferential direction.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

本发明涉及安全式注射器领域，具体公开了一种主动自锁式注射器，包括针筒、针座、活塞组件、活塞杆护盖、针尖护帽、注射针、针尖防护套、弹簧、导向限位组件、初始卡合组件及触发环塞。初始状态下，触发环塞位于触发腔内且在初始状态下触发环塞与触发部不接触或接触但不足以让初始卡合组件相互脱离，触发环塞的内壁与针座之间密封，触发环塞的外壁与针筒内壁之间密封。上述结构中，通过设于触发腔内的触发环塞，由针筒靠近病人端的内部触发并释放针尖防护套，实现防止针尖外露及自锁的技术目的，该触发方式设计巧妙，在针筒与针尖防护套之外再无其他辅助触发的部件，具有结构简单、针筒的径向尺寸小、部件精简、生产成本低的技术优势。

Description

一种主动自锁式注射器 技术领域
本发明涉及安全式注射器领域，具体涉及一种主动自锁式注射器。
 背景技术
目前市面的安全式注射器种类繁多，大体上有两种技术路线，其中一种是针尖回缩式安全注射器，即在注射完成后，针尖可自动或手动回缩至针筒内或针尖防护套内，从而达到避免使用后的针尖刺伤使用者的风险。另一种技术路线则是触发式安全注射器，即针尖是相对针筒固定的，通常在针筒的外部设置可触发的针尖保护装置，在注射过程中，针筒相对针尖保护装置轴向运动，在注射完成时，针筒或活塞杆触发针尖保护装置，针尖保护装置被触发后足以覆盖注射针，以防止针尖外露。
基于上述两种技术路线的安全注射器，其结构较为复杂，生产成本较高，因此，有必要开发一种新的安全注射器，以解决现有技术的缺陷。
 技术问题
本发明要解决的技术问题是提供一种结构改进型的主动自锁式注射器，该主动自锁式注射器由针筒的内部实现触发，以实现结构简单、成本较低、可靠性更高的技术效果。
 技术解决方案
为了解决上述技术问题，本发明提供的技术方案如下：一种主动自锁式注射器，至少包括：
针筒，所述针筒内设有活塞组件；
针座，所述针座固定于针筒内靠近病人端的位置，所述针座的外壁与针筒的内壁之间形成靠近病人端一侧的弹簧腔和靠近活塞组件一侧的触发腔；
注射针，所述注射针固定于针座上且针尖由针筒的病人端伸出；
针尖防护套，所述针尖防护套用于覆盖使用过的注射针；
弹簧，所述弹簧位于弹簧腔内，所述弹簧靠近针尖的一端与针尖防护套接触；
导向限位组件，所述导向限位组件用于限制针尖防护套触发后相对针筒轴向运动的方向和极限位置；
初始卡合组件，所述初始卡合组件用于将针尖防护套保持在非触发状态且设有从触发腔内触发以使初始卡合组件相互脱离的触发部；
触发环塞，所述触发环塞位于触发腔内且在初始状态下触发环塞与触发部不接触或接触但不足以让初始卡合组件相互脱离，所述触发环塞的内壁与针座之间密封，所述触发环塞的外壁与针筒内壁之间密封。
一种优选的实施例，还包括止回部件，所述止回部件用于防止针尖防护套在防护状态下回缩。
一种优选的实施例，所述止回部件包括设于针筒病人端的止回臂，所述止回臂具有弹性，所述止回臂的自由端在径向方向上突出于针筒的外壁。
一种优选的实施例，所述针尖防护套靠近病人端的侧壁上设有贯穿侧壁槽孔，所述槽孔用于容纳止回臂伸出。
一种优选的实施例，所述活塞组件包括活塞杆和设于活塞杆端部的活塞，所述活塞杆的端部为用于推动触发环塞的推送部。
一种优选的实施例，所述针座远离病人端的一端与活塞杆靠近针座的一端端部之间设有相互匹配的嵌合机构。
一种优选的实施例，所述导向限位组件包括设于针筒外壁上的凸柱和设于针尖防护套侧壁上的导向限位槽，所述凸柱与导向限位槽适配。
一种优选的实施例，所述初始卡合组件包括设于针尖防护套上的弹性臂和贯穿针筒外壁的卡合槽，所述弹性臂的自由端设有沿径向向针尖防护套内部延伸的卡接块，所述卡接块与卡合槽靠近病人端的卡接端卡接。
一种优选的实施例，触发部包括与卡合槽远离卡接端的一侧连接的触发臂，所述触发臂具有弹性，初始状态下，所述触发臂的自由端位于卡接块的径向方向的内侧。
一种优选的实施例，所述弹性臂的自由端与止回臂的自由端在针尖防护状态下相互抵触。
一种优选的实施例，所述弹性臂的自由端在轴向方向上低于针尖防护套的端面。
一种优选的实施例，还包括套设于针尖防护套外部的针尖护帽，所述针尖护帽在初始状态下覆盖所述弹性壁的自由端。
一种优选的实施例，还包括与针筒远离病人端的一端连接的活塞杆护盖。
 有益效果
本实施例的主动自锁式注射器，通过设于触发腔内的触发环塞，由针筒靠近病人端的内部触发并释放针尖防护套，以实现防止针尖外露及自锁的技术目的，该触发方式设计巧妙，在针筒与针尖防护套之外再无其他辅助触发的部件，具有结构简单、针筒的径向尺寸小、部件精简、生产成本低的技术优势。
 附图说明
图1所示为本实施例主动自锁式注射器的外部结构示意图；
图2所示为本实施例主动自锁式注射器的爆炸状态结构示意图；
图3所示为本实施例主动自锁式注射器的在初始状态（未触发）的局部剖视图；
图4所示为本实施例主动自锁式注射器中针筒的局部剖视图；
图5所示为本实施例主动自锁式注射器在针尖保护状态下的局部剖视图；
图6所示为本实施例主动自锁式注射器在未使用状态下的结构示意图。
 本发明的最佳实施方式
在此处键入本发明的最佳实施方式描述段落。
 本发明的实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，以下结合附图及实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
如图1、图2所示，本实施例的一种主动自锁式注射器，包括针筒10、活塞组件、注射针60、针尖防护套30、弹簧70以及针尖护帽40。在本实施例中，为了便于说明结构，定义主动自锁式注射器的注射针一端为病人端。
在本实施例中，其中活塞组件装配于针筒中，其结构如图2、图3所示，包括活塞杆20和活塞23，其中活塞杆20靠近病人端的一端设有活塞环槽22，该活塞环槽22中套设有活塞23，其中活塞23和活塞杆20为现有技术中常用的活塞和活塞杆，活塞23由柔性材料制成，活塞23与活塞环槽22之间密封，同时，活塞23并与针筒10的内壁之间密封，通过活塞组件的推拉实现药液的吸入和注射。
作为本实施例的改进之处，其中活塞杆20的端部设有推送部21，该推送部21的作用在于推动触发环塞50轴向运动，其中推送部21的端面与触发环塞50的端面相适应。
作为本实施例的改进之处，如图4所示，针座16固定于针筒10内靠近病人端的位置，注射针60固定于针座16上且针尖由针筒10的病人端伸出。上述针座16的外壁与针筒的内壁之间固定连接，并形成靠近病人端一侧的弹簧腔17和靠近活塞组件一侧的触发腔18。
一种优选的实施例，如图3、图5所示，针座16远离病人端的一端与活塞杆20靠近针座的一端端部之间设有相互匹配的嵌合机构，用于减少注射过程中药液的残留量。作为优选，该嵌合机构包括设于针座端部的外锥面19和位于活塞杆端部的锥形槽24。当然，锥形槽也可以设置于针座端部，外锥面设于活塞杆端部。外锥面和锥形槽也可以为外弧面和弧形槽。凡是技术构思与本实施例中嵌合机构相同的本领域等同技术手段，均视为本申请的等同技术方案。
如图3、图4所示，其中触发腔18内安装有触发环塞50，该触发环塞50内壁与针座16的外壁之间密封，所述触发环塞50的外壁与针筒内壁之间密封。本实施例中，触发环塞50在触发腔内可轴向移动，该触发环塞50的移动通过推送部21的推动实现。
在本实施例中，如图3、图4所示，针尖防护套30用于覆盖使用过的注射针60，该针尖防护套30在初始状态下套设于针筒的病人端。其中在针尖防护套30与针筒之间设有弹簧70，该弹簧70位于弹簧腔17内，该弹簧靠近针尖的一端与针尖防护套接触。初始状态下，弹簧70处于压缩储能状态，为针尖防护套的弹射提供预弹性力。
在本实施例中，针尖防护套30与针筒10之间设有初始卡合组件，用于将针尖防护套30保持在非触发状态。如图2、图3所示，本实施例一种优选的初始卡合组件包括设于针尖防护套上的弹性臂32和贯穿针筒外壁的卡合槽12，其中弹性臂32的自由端设有沿径向向针尖防护套内部延伸的卡接块33，该卡接块与卡合槽靠近病人端的卡接端13卡接。
需要说明的是，卡合槽12位于触发腔18所在的针筒外壁上，初始卡合组件还包括从触发腔18内触发以使初始卡合组件相互脱离的触发部。作为优选，该触发部包括与卡合槽远离卡接端的一侧连接的触发臂14，该触发臂14具有弹性，初始状态下，如图3所示，所述触发臂14的自由端位于卡接块的径向方向的内侧。
一种优选的实施例，如图1、图2所示，针尖防护套30与针筒10之间设有导向限位组件，该导向限位组件用于限制针尖防护套30触发后相对针筒轴向运动的方向和极限位置。作为优选，本实施例中的导向限位组件包括设于针筒外壁上的凸柱11和设于针尖防护套侧壁上的导向限位槽31，其中凸柱与导向限位槽适配，用于限制针尖防护套30与针筒10之间的相对旋转，只能沿轴向移动，并且，导向限位槽31的端部限制了针尖防护套30轴向移动的极限位置。
初始状态下，本实施例的主动自锁式注射器的触发环塞50位于触发腔18内且在初始状态下触发环塞与触发部不接触或接触但不足以让初始卡合组件相互脱离。使用过程中，首先活塞组件向远离针尖的一端移动，将药液吸入针筒内。注射过程中，活塞组件向针尖的一端移动，在活塞组件推进的过程中，推送部21首先与触发环塞50接触，并在接触后继续推动触发环塞50轴向移动，该触发环塞50驱使触发臂14向外逐渐扩张，由触发臂14驱动卡接块33沿径向向外逐渐变形，以使卡接块33与卡接端13脱离。卡接块33与卡接端13在药液注射完成时已经完全脱离，此时由于注射针还未从患者皮肤拔出，针尖防护套30的病人端与患者皮肤接触，在将注射针从患者皮肤拔出的过程中，弹簧70储存的势能得以释放，驱使针尖防护套30覆盖使用过的注射针，防止注射针外露伤人并实现自锁。
作为本实施例的改进之处，还包括用于防止针尖防护套在防护状态下回缩的止回部件。作为优选，如图2-5所示，本实施例的止回部件包括设于针筒病人端的止回臂15。其中止回臂15具有弹性，该止回臂15的自由端在径向方向上突出于针筒的外壁。
如图5所示，针尖防护状态下，所述弹性臂32的自由端与止回臂15的自由端在针尖防护状态下相互抵触实现自锁。由于止回臂15在径向方向上突出于针筒的外壁，该止回臂15的自由端所在的外径大于弹性臂32的自由端所在的外径，从而实现防止针尖防护套回缩，该止回部件使得防护可靠性较好。
一种优选的实施例，如图1-3所示，针尖防护套30靠近病人端的侧壁上设有贯穿侧壁槽孔34，该槽孔34用于容纳初始状态下止回臂伸出。
一种优选的实施例，如图2所示，针尖防护套的外壁上设有通槽36，弹性臂32位于该通槽36。其中弹性臂32的自由端在轴向方向上可以高于或低于针尖防护套30的端面，也可以与针尖防护套30的端面平齐。作为优选，弹性臂32的自由端在轴向方向上低于针尖防护套30的端面，如此设置的目的在于，减小针尖防护套的行程，保证弹簧的弹射力将针尖防护套弹射到位。
一种优选的实施例，如图1、图6所示，本实施例的主动自锁式注射器还设置有活塞杆护盖80，该活塞杆护盖80在初始未使用状态下套设于针筒远离病人端的一端，用于防止推动活塞杆，避免误触发针尖防护套。
一种优选的实施例，如图1、图6所示，本实施例中，针尖护帽40套设于针尖防护套30上，作为优选，针尖防护套上还设有与针尖护帽的端部接合的台阶面35。需要说明的是，针尖护帽安装于针尖防护套上时，其覆盖于弹性臂32的自由端上。如此设置的目的在于，即使推动活塞杆，由于弹性臂32被压住不具有变形空间，触发环塞无法进入触发臂内部的触发空间，同样可以避免误触发针尖防护套。
需要说明的是，在本实施例中，导向限位组件、初始卡合组件及止回部件的数量均为两组，沿圆周方向均布设置。当然，这只是最佳实施例，其中导向限位组件、初始卡合组件及止回部件的数量也可以为一组或三组以上，三组以上的情况下沿圆周方向分布设置，优选为沿圆周方向均布设置。
总之，以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等，均应包含在本发明的保护范围之内。
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Claims (12)

  1. 一种主动自锁式注射器，其特征在于，至少包括：
    针筒（10），所述针筒内设有活塞组件；
    针座（16），所述针座固定于针筒内靠近病人端的位置，所述针座的外壁与针筒的内壁之间形成靠近病人端一侧的弹簧腔（17）和靠近活塞组件一侧的触发腔（18）；
    注射针（60），所述注射针固定于针座上且针尖由针筒的病人端伸出；
    针尖防护套（30），所述针尖防护套用于覆盖使用过的注射针；
    弹簧（70），所述弹簧位于弹簧腔内，所述弹簧靠近针尖的一端与针尖防护套接触；
    导向限位组件，所述导向限位组件用于限制针尖防护套触发后相对针筒轴向运动的方向和极限位置；
    初始卡合组件，所述初始卡合组件用于将针尖防护套保持在非触发状态且设有从触发腔内触发以使初始卡合组件相互脱离的触发部；
    触发环塞（50），所述触发环塞位于触发腔内且在初始状态下触发环塞与触发部不接触或接触但不足以让初始卡合组件相互脱离，所述触发环塞的内壁与针座之间密封，所述触发环塞的外壁与针筒内壁之间密封。
  2. 按照权利要求1所述的主动自锁式注射器，其特征在于，还包括止回部件，所述止回部件用于防止针尖防护套在防护状态下回缩。
  3. 按照权利要求2所述的主动自锁式注射器，其特征在于，所述止回部件包括设于针筒病人端的止回臂（15），所述止回臂具有弹性，所述止回臂的自由端在径向方向上突出于针筒的外壁。
  4. 按照权利要求3所述的主动自锁式注射器，其特征在于，所述针尖防护套靠近病人端的侧壁上设有贯穿侧壁槽孔（34），所述槽孔用于容纳止回臂伸出。
  5. 按照权利要求1-4任一项所述的主动自锁式注射器，其特征在于，所述活塞组件包括活塞杆（20）和设于活塞杆端部的活塞（23），所述活塞杆的端部为用于推动触发环塞的推送部（21）。
  6. 按照权利要求5所述的主动自锁式注射器，其特征在于，所述针座（16）远离病人端的一端与活塞杆（20）靠近针座的一端端部之间设有相互匹配的嵌合机构。
  7. 按照权利要求1-4或6任一项所述的主动自锁式注射器，其特征在于，所述导向限位组件包括设于针筒外壁上的凸柱（11）和设于针尖防护套侧壁上的导向限位槽（31），所述凸柱与导向限位槽适配。
  8. 按照权利要求2-4或6任一项所述的主动自锁式注射器，其特征在于，所述初始卡合组件包括设于针尖防护套上的弹性臂（32）和贯穿针筒外壁的卡合槽（12），所述弹性臂的自由端设有沿径向向针尖防护套内部延伸的卡接块（33），所述卡接块与卡合槽靠近病人端的卡接端（13）卡接。
  9. 按照权利要求8所述的主动自锁式注射器，其特征在于，触发部包括与卡合槽远离卡接端的一侧连接的触发臂（14），所述触发臂具有弹性，初始状态下，所述触发臂的自由端位于卡接块的径向方向的内侧。
  10. 按照权利要求8所述的主动自锁式注射器，其特征在于，所述弹性臂的自由端与止回臂的自由端在针尖防护状态下相互抵触。
  11. 按照权利要求9或10所述的主动自锁式注射器，其特征在于，还包括套设于针尖防护套外部的针尖护帽（40），所述针尖护帽在初始状态下覆盖所述弹性壁（32）的自由端。
  12. 按照权利要求1-4或6或9-10任一项所述的主动自锁式注射器，其特征在于，还包括与针筒远离病人端的一端连接的活塞杆护盖（80）。
PCT/CN2018/120170 2018-09-12 2018-12-11 一种主动自锁式注射器 WO2020052122A1 (zh)

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Families Citing this family (2)

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Publication number Priority date Publication date Assignee Title
CN113440687B (zh) * 2020-03-24 2024-05-03 丽珠医药集团股份有限公司 植入注射器
CN114306820A (zh) * 2021-12-07 2022-04-12 李文琪 一种隆鼻塑型器

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2678665Y (zh) * 2003-11-26 2005-02-16 吕海洋 自动防护套管式安全注射器
CN101563124A (zh) * 2006-09-06 2009-10-21 特克法马许可公司 带有远侧和近侧针保护器的针保护装置
US20110288491A1 (en) * 2008-03-13 2011-11-24 Becton, Dickinson And Company Safety needle assembly
CN102631729A (zh) * 2012-04-17 2012-08-15 山东新华安得医疗用品有限公司 一次性使用安全注射器
CN108430543A (zh) * 2015-12-30 2018-08-21 诺和诺德股份有限公司 具有针护罩触发的自动注射器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9480799B2 (en) * 2009-04-08 2016-11-01 Stat Medical Devices, Inc. Retractable needle assembly utilizing a standard interface and syringe utilizing the same
US10220156B2 (en) * 2012-04-25 2019-03-05 Adar Medtech, Inc. Single use injector
CN104307072A (zh) * 2014-10-29 2015-01-28 杭州普昂医疗科技有限公司 安全式胰岛素笔针

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2678665Y (zh) * 2003-11-26 2005-02-16 吕海洋 自动防护套管式安全注射器
CN101563124A (zh) * 2006-09-06 2009-10-21 特克法马许可公司 带有远侧和近侧针保护器的针保护装置
US20110288491A1 (en) * 2008-03-13 2011-11-24 Becton, Dickinson And Company Safety needle assembly
CN102631729A (zh) * 2012-04-17 2012-08-15 山东新华安得医疗用品有限公司 一次性使用安全注射器
CN108430543A (zh) * 2015-12-30 2018-08-21 诺和诺德股份有限公司 具有针护罩触发的自动注射器

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