WO2020042294A1 - 自转位清洗装置及用于光固化组织工程支架清洗的装置 - Google Patents

自转位清洗装置及用于光固化组织工程支架清洗的装置 Download PDF

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Publication number
WO2020042294A1
WO2020042294A1 PCT/CN2018/110683 CN2018110683W WO2020042294A1 WO 2020042294 A1 WO2020042294 A1 WO 2020042294A1 CN 2018110683 W CN2018110683 W CN 2018110683W WO 2020042294 A1 WO2020042294 A1 WO 2020042294A1
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WIPO (PCT)
Prior art keywords
cleaning
self
liquid
fixing ring
cleaning device
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Ceased
Application number
PCT/CN2018/110683
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English (en)
French (fr)
Inventor
黄传真
王真
王军
邹斌
刘含莲
朱洪涛
姚鹏
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Shandong University
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Shandong University
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Publication date
Priority claimed from CN201821411012.3U external-priority patent/CN208800488U/zh
Priority claimed from CN201810999845.4A external-priority patent/CN109047171B/zh
Application filed by Shandong University filed Critical Shandong University
Priority to US16/479,828 priority Critical patent/US11338515B2/en
Publication of WO2020042294A1 publication Critical patent/WO2020042294A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B29C64/35—Cleaning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04—Cleaning involving contact with liquid
    • B08B3/045—Cleaning involving contact with liquid using perforated containers, e.g. baskets, or racks immersed and agitated in a liquid bath
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04—Cleaning involving contact with liquid
    • B08B3/08—Cleaning involving contact with liquid the liquid having chemical or dissolving effect
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04—Cleaning involving contact with liquid
    • B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
    • B08B3/12—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y40/00—Auxiliary operations or equipment, e.g. for material handling
    • B33Y40/20—Post-treatment, e.g. curing, coating or polishing

Definitions

  • the invention relates to an indexing cleaning device, in particular to an indexing cleaning device for cleaning a tissue engineering support in the field of light curing 3D printing technology.
  • 3D printing also known as additive manufacturing, rapid prototyping, free solid forming
  • Photocuring 3D printing uses a photosensitive resin (or a mixture of photosensitive resin and ceramics) as the processing material. This material is cured with laser scanning, then driven by CAD models and stacked layer by layer to form a three-dimensional solid model.
  • tissue engineering is the ultimate goal of forming biologically functional tissues or organs in vitro to repair, improve or enhance the function of the corresponding site.
  • the growth of tissue cells in vitro requires a porous scaffold structure to serve as an extracellular matrix to construct a suitable in vitro environment to maintain various physiological activities of the cell. Therefore, this tissue engineering scaffold needs to have a complex and controllable inner pore structure.
  • the advantages of cured 3D printing technology can be fully realized.
  • tissue engineering scaffolds Although light-cured 3D printed tissue engineering scaffolds are still in the experimental research stage, they have broad development prospects and have far-reaching significance for human life and health. More and more from biological science, materials science, manufacturing science and other fields Of experts are dedicated to this area of research. Manufacture of tissue engineering scaffolds using photo-curing 3D printing technology, although showing good results, but the photosensitive resin has a sticky nature, and has a great harm to the cells, even the material mixed with the photosensitive resin and ceramic, even after laser curing It must be completely clear and clean, otherwise it will affect the dimensional accuracy after ceramic sintering. Although there are currently cleaning devices for light-cured parts, these devices are only effective for ordinary industrial parts. Tissue engineering scaffolds have complex, numerous, and micro-internal structural features, which are very different from ordinary industrial parts, so the current cleaning devices for various light-cured parts are difficult to handle.
  • the purpose of the present invention is to solve the problems existing in current cleaning devices, especially to effectively clean the inner holes of photo-curable tissue engineering scaffolds, and to provide an indexing cleaning device which can be used for the inner holes of photo-curing tissue engineering scaffolds.
  • the device uses a combination of pressure perfusion and ultrasonic cleaning.
  • the device can thoroughly clean parts with complex, numerous, and small internal hole structure characteristics. Specifically, it can clean light-cured tissue engineering scaffolds, which can not only eliminate The residual liquid resin adversely affects the mechanical and biological properties of the tissue engineering scaffold, and does not cause any damage to the tissue engineering scaffold during the cleaning process.
  • An indexing cleaning device is composed of an outer casing, an inner casing, a workpiece indexing system, an ultrasonic cleaning system, and a fluid perfusion system;
  • An inner shell is provided along the horizontal direction in the outer shell, and a cylindrical cavity is formed inside the inner shell.
  • One end of the inner shell is provided with a sealing cover detachably connected to the inner shell, and the other end is closed.
  • the workpiece indexing system is disposed in the cavity, and is used for fixing the cleaning parts to be cleaned, and using fluid kinetic energy to realize the self-rotation of the cleaning parts;
  • the ultrasonic cleaning system provides mechanical energy to the cleaning liquid of the inner casing, thereby generating tiny air bubbles inside the liquid, and these air bubbles peel off the residual resin adhered to the surface of the cleaning member through continuous vibration and continuous burst;
  • the fluid perfusion system provides self-rotating power for the cleaning member on the one hand, and continuously delivers the cleaning liquid to the inside of the cleaning member, and the cleaning liquid is transported out after the cleaning is achieved.
  • the front and rear ends of the inner casing are respectively provided with an inlet and an outlet connected to the fluid perfusion system, and the outer surface is provided with four vibrator attachment tracks on the upper, lower, left, and right sides, respectively.
  • the vibrator attachment track is a flat surface
  • a rear end surface of the inner casing is a hemispherical concave surface.
  • the workpiece indexing system includes a cylindrical fixed basket, a disc-shaped magnet, and a propeller; the cylindrical fixed basket is disposed in an inner housing, and one end is provided with a basket cover detachably connected to the cylindrical fixed basket, and the other end passes through A disk-shaped magnet is adsorbed on the top platform of the propeller; the propeller shaft is installed at the end of the inner casing, and the fluid perfusion system can push the propeller to rotate.
  • cylindrical fixed basket is made of stainless steel, and the area of each mesh of the cylindrical fixed basket should be between 50-500 mm 2 .
  • the diameter of the bottom surface of the disk-shaped magnet should be between 25% and 40% of the diameter of the bottom surface of the cylindrical fixed basket. If the diameter of the bottom surface of the disk-shaped magnet is too small, it will not adsorb firmly, and if it is too large, it will hinder fluid flow. .
  • the blade diameter of the propeller should be between 40% and 85% of the diameter of the bottom surface of the cylindrical fixed basket, and a protruding top platform is provided in the middle of the propeller, and the diameter of the top platform is equal to the diameter of the bottom surface of the disc-shaped magnet.
  • the top of the propeller shaft is a protruding hemisphere, which is rotatably connected to the hemispherical concave surface at the rear end of the inner cavity.
  • the ultrasonic cleaning system includes a handle, four vibrators, an ultrasonic generator, four springs, an inner fixing ring, an outer fixing ring, three sliders, two links, four levers, and four fulcrum points.
  • the ultrasonic generator is installed on the outer side of the outer casing; the inner fixing ring and the outer fixing ring are coaxially installed with the inner casing, and are sequentially arranged on the outer ring of the inner casing, and the inner fixing ring
  • the four vibrator heads Four vibrator attachment tracks that fit on the outer surface of the inner casing, and the handles of the four vibrators each pass through a spring, so that the springs are located between the vibrator head and the inner fixing ring, of which two vibrator handles
  • the ends of the two parts are connected to the lever, and the ends of the handles of the other two oscillators are connected to the connecting rod;
  • the handle is connected to one of the connecting rods through the housing and the outer fixing ring;
  • the three sliders are provided on the outer fixing ring
  • the outer part can
  • the inner fixing ring is provided with 4 small holes, and the diameter of the hole is between the diameter of the head and the handle of the 4 vibrators.
  • three slideways are provided on the top and left and right sides of the outer shell, and the outer shell is further provided with a liquid injection port.
  • the fluid perfusion system includes a pump, a governor, and a liquid storage tank; the pump and the governor are connected by a wire, the pump is fixed at the bottom of the outer casing, and the outlet of the pump is connected to the front end of the inner casing through a pipeline.
  • the liquid inlet is connected; the top of the liquid storage tank is provided with a liquid injection port, a filter is arranged in the middle of the liquid storage tank, an inlet is provided on the wall of the upper part of the filter, and an outlet is provided on the wall of the lower part of the filter;
  • the inlet of the liquid storage tank is connected to the liquid outlet at the rear end of the inner casing through a pipe, the outlet of the liquid storage tank is connected to the pump inlet through a pipe, and the liquid injection port of the liquid storage tank is connected to the liquid injection port on the outer casing through the pipe.
  • the cleaning solution uses anhydrous ethanol.
  • a device for cleaning a light-cured tissue engineering scaffold which is characterized by adopting the aforementioned self-position cleaning device.
  • the present invention is a special cleaning device designed for the complicated, numerous and small structural features of the inner holes of some cleaning parts; the cleaning parts are placed in a fixed basket, and then the fixed basket is adsorbed on the top platform of the propeller by a disc-shaped magnet .
  • the vibrator in the ultrasonic cleaning system converts electrical energy into mechanical energy according to a certain ultrasonic frequency and transmits it to the cleaning liquid in the inner cavity, thereby generating tiny bubbles inside the liquid. These bubbles will continue to vibrate and burst, which will adhere to the surface of the cleaning part. Residual dirt is peeled off.
  • the ultrasonic cleaning system also realizes free adjustment of the vibrator in the axial direction of the cavity through a set of connecting rod levers.
  • the fluid perfusion system pushes the propeller on the one hand, so that the cleaning parts placed in the fixed basket continue to rotate, and on the other hand, the cleaning liquid is continuously delivered to the inside of the cleaning parts, and the dirt is dissolved in the cleaning liquid. It is then shipped out.
  • the present invention adopts a cleaning method combining fluid perfusion and ultrasonic, using a set of workpiece indexing system to realize self-rotation of the cleaning part while cleaning, and using a set of link levers to achieve free adjustment of the vibrator in the axial direction of the inner cavity.
  • the invention can not only clean the surface of the light-cured parts, but also thoroughly clean the micro-inner hole structure of the tissue engineering scaffold formed by the light-cured. Adjusting the fluid perfusion pressure and ultrasonic frequency can adapt to tissue engineering scaffolds with different internal hole sizes and different structural strengths, and it will not cause damage to the tissue engineering scaffold during the cleaning process, and the use of anhydrous ethanol as a cleaning agent will not affect tissue engineering.
  • the scaffold causes pollution and does not adversely affect its biological performance.
  • the entire cleaning device has a compact structure and a small volume, which is convenient to carry and easy to operate.
  • the invention can also be applied to the cleaning of parts and components in other fields.
  • FIG. 1 is a schematic diagram of the appearance of the present invention
  • FIG. 2 is a schematic diagram of an internal structure of the present invention.
  • FIG. 3 is a schematic structural diagram of an ultrasonic cleaning system of the present invention.
  • FIG. 4 is a schematic structural diagram of a fixed basket according to the present invention.
  • FIG. 5 is a schematic structural diagram of a propeller of the present invention.
  • FIG. 6 is a photo-curable tissue engineering scaffold after cleaning according to the present invention.
  • the “vibrator attachment track” in the present invention refers to a track for vibrator attachment.
  • this application proposes a self-position cleaning device.
  • the following takes the cleaning of a photo-curable tissue engineering scaffold as an example to describe the specifics of the self-position cleaning device.
  • the structure is explained in detail, and the overall outline drawing is shown in FIG. 1, which is composed of an outer shell 1, an inner shell 31, a workpiece indexing system, an ultrasonic cleaning system, and a fluid perfusion system.
  • an inner shell 31 is provided in the outer shell 1 along the horizontal direction, the inner shell forms a cylindrical inner cavity 11, and one end of the inner shell 31 is matched with the sealing cover 3.
  • a sealing gasket 4 is provided between the inner casing 31 and the sealing cover 3, and the inner casing 31 and the sealing cover 3 are detachably connected by the sealing cover buckle 2.
  • the other end of the inner casing 31 is sealed and can be connected to the inner casing.
  • the integrally formed seal may also be a seal realized by an end cover; the front and rear ends of the inner casing 31 are respectively provided with a liquid inlet 12-1 and a liquid outlet 12-2, and a rear end of the inner casing 31 is further provided.
  • the inner surface of the inner case 31 is cylindrical, and the upper surface, the lower surface, the left surface, and the right surface of the inner casing 31 are provided with four vibrator attachment tracks 25-1, 25-2, 25-3, and 25- 4.
  • the vibrator attachment track is a flat surface.
  • the outer case 1, the inner case 31, and the sealing cover 3 are all made of stainless steel.
  • one end of the inner shell 31 mating with the sealing cover 3 and the outer wall of the outer shell 1 are basically located on a plane to facilitate the placement and removal of the tissue engineering support, and the other end of the inner shell is located in the outer shell 1.
  • three slideways 9-1, 9-2, and 9-3 are provided on the top of the outer casing 1 and the left and right sides of the outer casing 1, and a liquid injection port 12-7 is also provided on the back of the outer casing 1.
  • the workpiece indexing system includes a cylindrical fixed basket 10, a disc-shaped magnet 17, and a propeller 16.
  • the cylindrical fixed basket 10 is made of stainless steel, the area of each mesh of the cylindrical fixed basket 10 should be 80mm 2 -150mm 2 , the cylindrical fixed basket 10 is provided with a basket cover 26 at one end, and the cylindrical fixed basket 10 10 and the basket cover 26 form a detachable connection through the basket cover buckle 27.
  • One bottom surface of the disc-shaped magnet 17 is adsorbed on the bottom of the cylindrical fixed basket 10, and the other bottom surface is adsorbed on the top platform 28 of the propeller 16.
  • the top end of the rotary shaft 29 of the propeller 16 is a protruding hemisphere 30, which is rotatably connected with the hemispherical concave surface at the bottom of the inner cavity 11.
  • the ultrasonic cleaning system includes a handle 5, 4 vibrators 15-1, 15-2, 15-3, and 15-4, an ultrasonic generator 6, and 4 springs 14-1, 14-2, and 14-3. And 14-4, inner fixing ring 23, outer fixing ring 24, 3 sliders 8-1, 8-2 and 8-3, 2 connecting rods 20-1 and 20-2, 4 levers 21-1, 21-2, 21-3 and 21-4, 4 pivot points 22-1, 22-2, 22-3 and 22-4.
  • the ultrasonic generator 6 is mounted on the outer surface of the outer casing 1.
  • the four vibrators 15 are respectively located on the four vibrator attaching tracks 25 on the outer surface of the inner case 31.
  • the inner fixing ring 23 surrounds the outside of the four vibrators 15.
  • the inner fixing ring 23 is provided with four small holes, and the diameter of the holes is between the diameters of the heads and the shanks of the four oscillators.
  • the handles of the four vibrators 15 pass through four springs 14 so that the 14 position of the springs is between the head of the vibrator 15 and the inner fixing ring 23.
  • the two connecting rods 20 and the four levers 21 surround the outside of the inner fixing ring 23, and the four levers 21 and the four fulcrum points 22 are in contact with each other.
  • the outer fixing ring 24 surrounds the outer sides of the two connecting rods 20 and the four levers 21.
  • Sliders 8 are provided on the top and left and right sides of the outer fixing ring 24.
  • the slideway 9 forms a sliding connection.
  • Lever 21-1 and lever 21-4 have the same structure and are arranged symmetrically; Lever 21-2 and lever 21-3 have the same structure and are arranged symmetrically; Lever 21-1, Lever 21-2, Link 20-2, Lever 21 -3, the lever 21-4 and the connecting rod 20-1 are connected in sequence to form a circle.
  • the end of the handle of vibrator 15-2 is fixed to the lever 21-1; the end of the handle of vibrator 15-3 is fixed to the link 20-2; the end of the handle of vibrator 15-4 is fixed to the lever 21-4; vibrator 15-1
  • the end of the handle is fixedly connected to the connecting rod 20-1.
  • the inner fixing ring 23, the four fulcrum points 22 and the outer fixing ring 24 are rigidly connected.
  • the handle 5, the connecting rod 20-1 and the vibrator 15-1 are rigidly connected.
  • the four oscillators, four springs, the inner fixing ring 23, the outer fixing ring 24, three sliders, two connecting rods, four levers, and four fulcrum points are symmetrically distributed in a left-right symmetrical manner as a whole. According to the structure on the left, the transmission principle of the above-mentioned ultrasonic cleaning system is further explained: when the handle 5 is lifted up, the spring 14-1 is compressed, the vibrator 15-1 leaves the vibrator attachment track 25-1, and the connecting rod 20-1 is outward.
  • the connecting rod 20-1 slides the lever 21-1 around the fulcrum 22-1, and the upper end of the lever 21-1 rotates outward, which drives the vibrator 15-2 away from the vibrator attachment track 25-2, and the lower end of the lever 21-1 moves inward Rotation causes the lever 21-2 to rotate around the fulcrum 22-2.
  • the lower end of the lever 21-2 rotates outward, which drives the link 20-2 to move downward, and then drives the vibrator 15-3 to leave the vibrator attachment track 25-3.
  • the handle 5 is moved forward and backward by external force, so that the four vibrators can be moved along the axis of the inner cavity 11.
  • the fluid perfusion system includes a pump 13, a governor 7, and a liquid storage tank 19.
  • the pump 13 and the governor 7 are connected by a wire.
  • the pump 13 is fixed at the bottom of the outer casing 1, and the pump outlet 12-6 communicates with the liquid inlet 12-1 at the front end of the inner cavity 11 through a pipeline.
  • the top of the liquid storage tank 19 is provided with a liquid storage tank injection port 12-8, a filter screen 18 is provided in the middle of the liquid storage tank 19, and a liquid storage tank inlet 12-3 is provided on the upper wall of the filter screen 18 to filter
  • the tank wall at the lower part of the net is provided with a liquid storage tank outlet 12-4.
  • the liquid storage tank inlet 12-3 is connected to the liquid outlet 12-2 at the rear end of the inner cavity 11 through a pipeline, the liquid storage tank outlet 12-4 is connected to the pump inlet 12-5 through a pipeline, and the liquid storage tank injection port 12- 8 is connected to the liquid injection port 12-7 of the shell through a pipeline.
  • the fluid infusion system uses anhydrous ethanol as a cleaning solution.
  • the pump 13 is a dedicated alcohol diaphragm pump.
  • the Unicom pipeline is a PVC pipe, because the resin is easily adhered and accumulated inside the PVC pipe, the PVC pipe must be replaced frequently.
  • the inner cavity 11 of the inner casing 31 has a diameter of 5 cm, an axial length of 8 cm, and the inner casing material is 3 mm thick stainless steel.
  • the four vibrator attachment tracks 25 of the outer contour of the inner casing 31 are processed by grinding or milling.
  • the transducer attachment rail 25 is a plane of 1 cm ⁇ 8 cm.
  • the cylindrical fixed basket 10 has a bottom diameter of 3.5 cm and an axial length of 5 cm.
  • the diameter of the bottom surface of the disk-shaped magnet 17 is 1 cm. If the diameter of the bottom surface of the disk-shaped magnet 17 is too small, the adsorption is not reliable, and if it is too large, the fluid flow is hindered.
  • the blade diameter of the propeller 16 is 3 cm.
  • a protruding top platform 28 is provided in the middle of the propeller 16, and the top platform 28 has a diameter of 1 cm.
  • Step 1 Place the light-cured tissue engineering scaffold in a cylindrical fixed basket 10, and then attach the entire fixed basket 10 to the top platform 28 of the propeller 16 through a disk-shaped magnet 17.
  • the hemisphere 30 at the top of the propeller 16 shaft 29 and A hemispherical concave surface at the bottom of the inner cavity 11 constitutes a rotatable connection. Close the sealing cap 3 and add an appropriate amount of absolute ethanol to the injection port 12-7;
  • Step 2 Adjust the frequency of the ultrasonic generator 6 to 40 kHz, adjust the flow rate of the governor 7 to 500 ml / min, and turn off the ultrasonic generator 6 and the governor 7 after stable operation for 3-5 minutes. Lift the handle upwards and move it forward or backward by 2-3cm to release the handle. Stable work again for 3-5min at the above frequency and flow rate;
  • Step 3 After replacing the absolute ethanol, adjust the frequency of the ultrasonic generator 6 to 30 kHz, adjust the flow rate of the governor 7 to 1000 ml / min, and shut down the ultrasonic generator 6 and the governor 7 after 3-5 minutes of stable operation. Lift the handle upwards and move it forward or backward by 2-3cm to release the handle. Stable work again for 3-5min at the above frequency and flow rate;
  • Step 4 Open the sealing cover buckle 2, open the sealing cover 3, and take out the fixed basket 10. After 10-20 minutes at room temperature, the absolute ethanol on the surface and inside of the tissue engineering scaffold is completely evaporated.
  • the tissue engineering scaffold formed by photo-curing is thoroughly cleaned, no resin remains in the inner hole, and the cleaning intensity is moderate without damage.
  • the self-inversion cleaning device proposed in this application can be used for cleaning alumina microporous ceramic parts.
  • Alumina microporous ceramic parts are mainly used for sewage treatment, heat insulation and sound insulation, etc. Because of its complex, numerous and tiny inner hole structure, it is difficult to achieve a good cleaning effect by ordinary cleaning methods.
  • This device aims at these Features are designed as follows:
  • the device is composed of an outer shell, an inner shell, a workpiece indexing system, an ultrasonic cleaning system, and a fluid perfusion system.
  • the outer shell, the inner shell, the workpiece indexing system, the ultrasonic cleaning system, and the fluid perfusion system are basically the same as those in Example 1.
  • the alumina microporous ceramic parts have a higher relative to the photo-curable tissue engineering scaffold in Example 1. Mechanical strength, so you can increase the cleaning strength appropriately, and adjust some of the structures in Example 1:
  • the area of each mesh of the cylindrical fixed basket should be 180 2 -300mm 2
  • a basket cover is provided at one end of the cylindrical fixed basket, and the cylindrical fixed basket and the basket cover are detachably connected;
  • the communication pipeline is a stainless steel hose
  • the diameter of the inner cavity of the inner casing is 10cm, the axial length is 15cm, and the inner cavity material is 3mm thick stainless steel.
  • the four vibrator attachment tracks of the inner casing are processed by grinding or milling, and the vibrator attachment tracks 1.5cm ⁇ 15cm plane;
  • the bottom surface of the fixed basket has a diameter of 7.5 cm and an axial length of 12 cm.
  • the diameter of the bottom surface of the disc-shaped magnet is 3 cm.
  • the blade diameter of the propeller is 6cm, and a protruding top platform is provided in the middle of the propeller, and the diameter of the top platform is 3cm.
  • Step 1 Place the alumina microporous ceramic parts in the fixed basket, and then adsorb the entire fixed basket on the top platform of the propeller through a disk-shaped magnet. Turn the connection. Close the sealing cap and add an appropriate amount of absolute ethanol to the injection port;
  • Step 2 Adjust the frequency of the ultrasonic generator to 30kHz, adjust the flow rate of the governor to 1500ml / min, and turn off the ultrasonic generator and the governor after stable operation for 7-10min.
  • Step 3 After replacing the absolute ethanol again, adjust the frequency of the ultrasonic generator to 20kHz, adjust the flow rate of the governor to 2500ml / min, and shut down the ultrasonic generator and the governor after 10-15min of stable operation. Firmly lift the handle up and move 4-6cm forward or backward to release the handle. Once again work stably for 10-15min at the above frequency and flow rate;
  • Step 4 Open the seal cover buckle, open the seal cover, and take out the fixed basket. After 10-20 minutes at room temperature, the surface and the inside of the alumina microporous ceramic parts are completely evaporated.
  • the application of the cleaning device can effectively clean the alumina microporous ceramic parts, in particular, it has a good cleaning effect on the soluble dirt in the tiny through holes, and the cleaning effect on the blind holes is relatively poor.

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  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
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  • Physics & Mathematics (AREA)
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  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cleaning By Liquid Or Steam (AREA)

Abstract

一种自转位清洗装置及用于光固化组织工程支架清洗的装置，由外壳体（1）、内壳体（31）、工件转位系统、超声波清洁系统和流体灌注系统组成；在外壳体（1）内沿着水平方向设有一个内壳体（31），内壳体（31）内部形成一个圆柱形空腔（11），内壳体（31）的一端设有与其可拆卸连接的密封盖（3），另一端封闭；工件转位系统设置在空腔（11）里，其用于固定待清洗的清洗件，并利用流体动能实现清洗件的自旋转；超声波清洁系统向内壳体（31）的清洗液提供机械能；流体灌注系统为清洗件提供自旋转的动力，不断的将清洗液输送到清洗件内部，清洗后运出。

Description

自转位清洗装置及用于光固化组织工程支架清洗的装置 技术领域
本发明涉及一种自转位清洗装置，特别是涉及一种在光固化3D打印技术领域中用于清洗组织工程支架的自转位清洗装置。
背景技术
目前，很多技术领域中都会应用到一些内孔复杂、繁多且微小的零部件，这些零部件清洗难度大，现有技术中还没有针对这类零部件专门的清洗设备，例如：近几年随着计算机辅助设计、材料加工与成形等各种技术的快速发展，3D打印(又称增材制造、快速原型、自由实体成型)已经应用在航空航天、汽车、医疗、消费品和教育等领域，并且呈现出越来越快的发展速度。光固化3D打印使用光敏树脂(或光敏树脂与陶瓷混合材料)作为加工材料，此种材料随着激光扫描而固化，然后由CAD模型驱动而层层堆叠，最后形成三维实体模型。一般认为在目前的3D打印技术中，光固化方法具有最高的成形精度。所以它越来越多的应用在各种复杂零件的制造，特别是在组织工程学领域，很多国内外学者从事多孔组织工程支架制造技术的研究。组织工程学是以在体外形成具有生物功能的组织或者器官为最终目标，用以修复、改善或提高相应的部位的功能。体外组织细胞的生长需要多孔支架类结构充当细胞外基质，构建合适的体外环境，维持细胞各种生理活动，所以这种组织工程支架需要具有形状复杂且可控的内孔结构，在此领域光固化3D打印技术的优势可以充分体现。
光固化3D打印组织工程支架虽然还处于实验研究阶段，但是其具有广阔的发展前景，对人类的生命健康具有极深远的意义，越来越多的来自生物科学、材料科学、制造科学等各个领域的专家致力于这方面的研究。用光固化3D打印技术制造组织工程支架，虽然展示出了很好的效果，但是光敏树脂具有黏稠的特性，且对细胞具有极大的危害，即使光敏树脂与陶瓷混合的材料，激光固化后也需彻底清晰干净，否则会影响陶瓷烧结成形后的尺寸精度。目前虽然有光固化零件的清洗装置，但是这些装置仅对普通的工业零件有效。而组织工程支架具有复杂、繁多、微小内孔的结构特点，与普通的工业零件有很大区别，所以目前的各种光固化零件的清洗装置很难胜任。
发明内容
本发明的目的是针对目前的清洗装置存在的问题，特别是针对光固化组织工程支架内孔进行有效清洗的问题，提供一种自转位清洗装置，其可以用于光固化组织工程支架的内孔清洗，该装置采用压力灌注与超声波结合的清洗方法，该装置能够对具有复杂、繁多、微小内孔结构特点的零部件进行彻底清洗，具体的能够对光固化组织工程支架进行清洗，不仅能消除残余的液体树脂对组织工程支架的力学和生物学性能的不利影响，而且不会在清洗过程中对组织工程支架造成任何破坏。
本发明采用的技术方案如下：
一种自转位清洗装置，由外壳体、内壳体、工件转位系统、超声波清洁系统和流体灌注系统组成；
在所述的外壳体内沿着水平方向设有一个内壳体，所述的内壳体内部形成一个圆柱形空腔，内壳体的一端设有与其可拆卸连接的密封盖，另一端封闭；
所述的工件转位系统设置在所述的空腔里，其用于固定待清洗的清洗件，并利用流体动能实现清洗件的自旋转；
所述的超声波清洁系统向内壳体的清洗液提供机械能，从而在液体内部产生微小气泡，这些气泡通过持续振动和不断爆裂，将附着在清洗件表面的残留树脂剥离；
所述的流体灌注系统一方面为清洗件提供自旋转的动力，另一方面不断的将清洗液输送到清洗件内部，实现清洗后，清洗液运出。
进一步的，所述内壳体的前、后两端分别设有与流体灌注系统液体相连的进口与出口，其外表面的上、下、左、右分别设有4条振子贴附轨道，所述振子贴附轨道为平面；且在内壳体后端面为一个半球形凹面。
进一步的，所述工件转位系统包括圆柱形固定篮、圆盘形磁石和螺旋桨；所述的圆柱形固定篮设置在内壳体内，其一端设有与其可拆卸连接的篮盖，另一端通过圆盘形磁石吸附在所述螺旋桨顶部平台上；所述的螺旋桨转轴安装在内壳体的端部，所述的流体灌注系统可以推动螺旋桨转动。
进一步的，所述圆柱形固定篮由不锈钢制成，圆柱形固定篮每个网孔的面积应在50-500mm 2之间。
进一步的，所述圆盘形磁石的底面直径应在上述圆柱形固定篮底面直径的25％—40％之间，圆盘形磁石的底面直径太小则吸附不牢靠，太大则阻碍流体流动。
进一步的，所述螺旋桨的叶片直径应在上述圆柱形固定篮底面直径的40％—85％之间，螺旋桨中间设有一个突出的顶部平台，顶部平台直径在上述圆盘形磁石的底面直径的80％—100％之间；螺旋桨转轴顶端为突出的半球形，其与上述内腔后端的半球形凹面组成可转动连接。
进一步的，所述超声波清洁系统包括手柄、四个振子、超声波发生器、四个弹簧、内固定环、外固定环、三个滑块、两个连杆、四个杠杆和四个支点。
所述超声波发生器安装在上述外壳体外侧面；所述的内固定环、外固定环与所述的内壳体同轴安装，依次设置在内壳体的外圈，在所述的内固定环和外固定环之间设有成环状分布的四个杠杆，四个杠杆分别与四个支点相互接触，且四个杠杆通过两个连杆连接成一个圈；所述的四个振子头部贴合在所述内壳体外表面的四条振子贴附轨道上，所述四个振子的柄部各自穿过一个弹簧，使弹簧位于振子头部和内固定环之间，其中两个振子的柄部末端连接在杠杆上，另外两个振子的柄部末端连接在连杆上；所述的手柄穿过外壳和外固定环与其中一个连杆相连；所述的3个滑块设置在外固定环的外部，可以沿着设置在外壳体内侧面的滑道滑动。
进一步的，所述内固定环上设有4个小孔，孔的直径大小在4个振子的头部与柄部直径之间。
进一步的，所述的外壳体顶部与左右两侧设有3条滑道，外壳体上还设有注液口。
进一步的，所述流体灌注系统包括泵、调速器和储液箱；所述的泵与调速器通过导线连接，泵固定在外壳体底部，泵的出口通过管道与所述内壳体前端的液体进口联通；所述储液箱的顶部设有注液口，储液箱中间设有过滤网，过滤网上部的箱壁上设有进口，过滤网下部的箱壁上设有出口；所述储液箱的进口通过管道与所述内壳体后端的液体出口联通，储液箱的出口通过管道与泵的入口联通，储液箱的注液口通过管道与外壳体上的注液口联通。
进一步的，所述的清洗液采用无水乙醇。
一种用于光固化组织工程支架清洗的装置，其特征在于，采用前面所述的自 转位清洗装置。
本发明的工作原理：
本发明是针对一些清洗件内孔复杂、繁多、微小的结构特点，而设计的专用清洗装置；将清洗件置于固定篮内，然后将固定篮通过圆盘形磁石吸附在螺旋桨的顶部平台上。超声波清洁系统里的振子将电能按照一定的超声频率转换成机械能，传递给内腔里的清洗液，从而在液体内部产生微小气泡，这些气泡通过持续振动和不断爆裂，将附着在清洗件表面的残留污物剥离。超声波清洁系统还通过一套连杆杠杆，实现振子在内腔轴线方向的自由调节。在超声波清洁系统工作的同时，流体灌注系统一方面推动螺旋桨转动，从而使置于固定篮内的清洗件持续转动，另一方面不断的将清洗液输送到清洗件内部，污物溶于清洗液后随其运出。
本发明的有益技术效果如下：
1.本发明采用流体灌注与超声波结合的清洗方法，利用一套工件转位系统实现清洗件在清洗的同时自转动，利用一套连杆杠杆实现振子在内腔轴线方向的自由调节。
2.本发明不仅可以对光固化零件的表面清洗，而且可以对光固化形成的组织工程支架的微小内孔结构进行彻底清洗。调节流体灌注压力和超声波频率，可以适应不同内孔尺寸和不同结构强度的组织工程支架，而且在清洗的过程中不会对组织工程支架产生损伤，以无水乙醇为清洗剂不会对组织工程支架造成污染，不会对其生物学性能造成不利影响。整个清洗装置结构紧凑、体积小，方便搬运，易于操作。
3.本发明还可以应用于其他领域中零部件的清洗。
附图说明
构成本申请的一部分的说明书附图用来提供对本申请的进一步理解，本申请的示意性实施例及其说明用于解释本申请，并不构成对本申请的不当限定。
图1为本发明的外观示意图；
图2为本发明的内部结构示意图；
图3为本发明的超声波清洁系统的结构示意图；
图4为本发明的固定篮的结构示意图；
图5为本发明的螺旋桨的结构示意图；
图6为利用本发明清洗后的一个光固化组织工程支架。
其中，1、外壳体，2、密封盖卡扣，3、密封盖，4、密封垫圈，5、手柄，6、超声波发生器，7、调速器，8-1、滑块，8-2、滑块，8-3、滑块，9-1、滑道，9-2、滑道，9-3、滑道，10、固定篮，11、内腔，12-1、液体进口，12-2、液体出口，12-3、储液箱进口，12-4、储液箱出口，12-5、泵进口，12-6、泵出口，12-7、注液口，12-8、储液箱注液口，13、泵，14-1、弹簧，14-2、弹簧，14-3、弹簧，14-4、弹簧，15-1、振子，15-2、振子，15-3、振子，15-4、振子，16、螺旋桨，17、圆盘形磁石，18、过滤网，19、储液箱，20-1、连杆，20-2、连杆，21-1、杠杆，21-2、杠杆，21-3、杠杆，21-4、杠杆，22-1、支点，22-2、支点，22-3、支点，22-4、支点，23、内固定环，24、外固定环。25-1、振子贴附轨道，25-2、振子贴附轨道，25-3、振子贴附轨道，25-4、振子贴附轨道，26、篮盖，27、篮盖卡扣，28、顶部平台，29、转轴，30、半球，31、内壳体。
具体实施方式
应该指出，以下详细说明都是例示性的，旨在对本申请提供进一步的说明。除非另有指明，本文使用的所有技术和科学术语具有与本申请所属技术领域的普通技术人员通常理解的相同含义。
需要注意的是，这里所使用的术语仅是为了描述具体实施方式，而非意图限制根据本申请的示例性实施方式。如在这里所使用的，除非上下文另外明确指出，否则单数形式也意图包括复数形式，此外，还应当理解的是，当在本说明书中使用术语“包含”和/或“包括”时，其指明存在特征、步骤、操作、器件、组件和/或它们的组合；
为了方便叙述，本发明中如果出现“上”、“下”、“左”“右”字样，仅表示与附图本身的上、下、左、右方向一致，并不对结构起限定作用,仅仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的设备或元件必须具有特定的方位，以特定的方位构造和操作，因此不能理解为对本发明的限制。
术语解释部分:本发明中的术语“安装”、“相连”、“连接”、“固定”等术语应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或为一体；可以是机械连接，也可以是电连接，可以是直接连接，也可以是通过中间媒介间接相连，可以是两个元件内部连接，或者两个元件的相互作用关系，对于本领域 的普通技术人员而言，可以根据具体情况理解上述术语在本发明的具体含义。
本发明中所述的“振子贴附轨道”是指用于振子贴附的轨道。
实施例1
正如背景技术所介绍的，现有技术中存在不足，为了解决如上的技术问题，本申请提出了一种自转位清洗装置，下面以清洗光固化组织工程支架为例，对自转位清洗装置的具体结构进行详细的说明，整体外形图如图1所示，其由外壳体1、内壳体31、工件转位系统、超声波清洁系统和流体灌注系统组成。
进一步的，在所述的外壳体1内沿着水平方向设有一个内壳体31，所述的内壳体形成一个圆柱形内腔11，内壳体31一端与密封盖3配合，所述内壳体31与密封盖3之间设有密封垫圈4，内壳体31与密封盖3通过密封盖卡扣2组成可拆卸连接；内壳体31的另一端密封，可以是与内壳体一体成型形成的密封，也可以是通过一个端盖实现的密封；所述内壳体31前后两端分别设有液体进口12-1与液体出口12-2，内壳体31后端还设有半球形凹面，内壳体31的内表面为圆柱形，其外表面的上、下、左、右分别设有4条振子贴附轨道25-1、25-2、25-3、和25-4，所述振子贴附轨道为平面。所述外壳体1、内壳体31和密封盖3均由不锈钢制成。
进一步的，内壳体31与密封盖3配合的一端与外壳体1外壁基本上位于一个平面上，以方便组织工程支架的放置和取出，内壳体的另一端位于外壳体1内。
进一步的，外壳体1顶部与外壳体1左右两侧设有3条滑道9-1、9-2和9-3，外壳体1背面还设有注液口12-7。
如图2和图3所示，所述工件转位系统包括圆柱形固定篮10、圆盘形磁石17和螺旋桨16。优选的，所述圆柱形固定篮10由不锈钢制成，圆柱形固定篮10每个网孔的面积应为80mm 2-150mm 2,圆柱形固定篮10一端设有篮盖26，圆柱形固定篮10与篮盖26通过篮盖卡扣27组成可拆卸连接。
所述圆盘形磁石17的一个底面吸附在圆柱形固定篮10底部，另一个底面吸附在螺旋桨16的顶部平台28上。
如图5所示，为本发明中的螺旋桨16的结构，螺旋桨16的转轴29顶端为 突出的半球30，其与上述内腔11底部的半球形凹面组成可转动连接。
进一步的，所述超声波清洁系统包括手柄5、4个振子15-1、15-2、15-3和15-4、超声波发生器6、4个弹簧14-1、14-2、14-3和14-4、内固定环23、外固定环24、3个滑块8-1、8-2和8-3、2个连杆20-1和20-2、4个杠杆21-1、21-2、21-3和21-4、4个支点22-1、22-2、22-3和22-4。所述超声波发生器6安装在上述外壳体1外侧面。所述4个振子15分别位于上述内壳体31外表面的4条振子贴附轨道25上。所述内固定环23环绕在4个振子15的外面，内固定环23上设有4个小孔，孔的直径大小在4个振子的头部与柄部直径之间。所述4个振子15的柄部穿过4个弹簧14，使弹簧14位与振子15头部和内固定环23之间。所述2个连杆20和4个杠杆21都环绕在内固定环23外侧，4个杠杆21分别与4个支点22相互接触。所述外固定环24环绕在2个连杆20和4个杠杆21的外侧，外固定环24的顶部和左右两侧都设有滑块8，3个滑块8与上述外壳体1的3条滑道9形成滑动连接。
杠杆21-1、杠杆21-4结构完全相同，对称布置；杠杆21-2、杠杆21-3结构完全相同，对称布置；杠杆21-1、杠杆21-2、连杆20-2、杠杆21-3，杠杆21-4和连杆20-1头尾依次连接形成一个圆圈。振子15-2的手柄末端与杠杆21-1固接；振子15-3的手柄末端与连杆20-2固接；振子15-4的手柄末端与杠杆21-4固接；振子15-1的手柄末端与连杆20-1固接。
进一步的，内固定环23、4个支点22和外固定环24三者之间为刚性连接。所述手柄5、连杆20-1和振子15-1三者之间为刚性连接。
进一步的，所述4个振子、4个弹簧、内固定环23、外固定环24、3个滑块、2个连杆、4个杠杆和4个支点整体为左右对称环形分布。根据左侧结构，进一步对上述超声波清洁系统的传动原理进行说明：当手柄5向上提起，弹簧14-1压缩，振子15-1离开振子贴附轨道25-1，同时连杆20-1向外侧运动，连杆20-1橇动杠杆21-1绕支点22-1转动，杠杆21-1上端往外侧转动，带动振子15-2离开振子贴附轨道25-2，杠杆21-1下端往内侧转动，带动杠杆21-2绕支点22-2转动，杠杆21-2下端往外侧转动，带动连杆20-2往下运动，继而带动振子15-3离开振子贴附轨道25-3。然后通过外力将手柄5前后移动，即可实现4个振子沿内腔11轴线运动。
进一步的，所述流体灌注系统包括泵13、调速器7和储液箱19。所述的泵13与调速器7通过导线连接，泵13固定在外壳体1底部，泵出口12-6通过管道与上述内腔11前端的液体进口12-1联通。所述储液箱19的顶部设有储液箱注液口12-8，储液箱19中间设有过滤网18，过滤网18上部的箱壁上设有储液箱进口12-3，过滤网下部的箱壁上设有储液箱出口12-4。所述储液箱进口12-3通过管道与上述内腔11后端的液体出口12-2联通，储液箱出口12-4通过管道与泵进口12-5联通，储液箱注液口12-8通过管道与上述壳体的注液口12-7联通。
进一步的，所述流体灌注系统采用无水乙醇作为清洗液。所述泵13为专用酒精隔膜泵。所述联通管道为PVC管，因为树脂的很容易粘结堆积在PVC管内部，所以PVC管必须经常更换。
具体的，下面以一些具体设计尺寸为例，进行进一步的说明：
例如：内壳体31的内腔11直径为5cm，轴向长度为8cm，内壳体材料为3mm厚的不锈钢，内壳体31外轮廓的4条振子贴附轨道25通过磨削或者铣削加工而成，振子贴附轨道25为1cm×8cm的平面。
圆柱形固定篮10底面直径为3.5cm，轴向长度为5cm。圆盘形磁石17的底面直径为1cm，圆盘形磁石17的底面直径太小则吸附不牢靠，太大则阻碍流体流动。螺旋桨16的叶片直径为3cm，螺旋桨16中间设有一个突出的顶部平台28，顶部平台28直径1cm。
本发明的具体工作过程如下：
步骤1，将光固化成型后的组织工程支架置于圆柱形固定篮10，然后通过圆盘形磁石17将整个固定篮10吸附在螺旋桨16顶部平台28上，螺旋桨16转轴29顶端的半球30与内腔11底部的半球形凹面组成可转动连接。盖好密封盖3，将适量的无水乙醇加入到注液口12-7；
步骤2，调节超声波发生器6频率为40kHz，调节调速器7流速为500ml/min，稳定工作3-5min后，关闭超声波发生器6和调速器7。用力向上提手柄，并往前或往后运动2-3cm，松开手柄。再一次按上述频率与流速稳定工作3-5min；
步骤3，重新更换无水乙醇后，调节超声波发生器6频率为30kHz，调节调速器7流速为1000ml/min，稳定工作3-5min后，关闭超声波发生器6和调速器 7。用力向上提手柄，并往前或往后运动2-3cm，松开手柄。再一次按上述频率与流速稳定工作3-5min；
步骤4，掰开密封盖卡扣2，打开密封盖3，取出固定篮10，室温条件下10-20min后，组织工程支架表面和内部的无水乙醇即完全挥发。
按此步骤，光固化形成的组织工程支架清洗彻底，内孔无树脂残留，清洗强度适中无损伤。
实施例2
本申请提出的自转位清洗装置，可以用于氧化铝微孔陶瓷零件的清洗。氧化铝微孔陶瓷零件主要用于污水处理、隔热和隔音等用途，因其具有复杂、繁多且微小的内孔结构，用普通的清洗方式很难达到比较好的清洗效果，本装置针对这些特点进行了如下设计：
本装置由外壳体、内壳体、工件转位系统、超声波清洁系统和流体灌注系统组成。
所述外壳体、内壳体、工件转位系统、超声波清洁系统和流体灌注系统与实施例1基本相同，氧化铝微孔陶瓷零件相对于实施例1中的光固化组织工程支架具有更高的机械强度，所以可适当增加清洗强度，对实施例1中的部分结构进行调整：
所述工件转位系统中，圆柱形固定篮每个网孔的面积应为180 2-300mm 2,圆柱形固定篮一端设有篮盖，圆柱形固定篮与篮盖组成可拆卸连接；
所述流体灌注系统中，联通管道为不锈钢软管；
所述内壳体的内腔直径为10cm，轴向长度为15cm，内腔材料为3mm厚的不锈钢，内壳体的4条振子贴附轨道通过磨削或者铣削加工而成，振子贴附轨道为1.5cm×15cm的平面；
所述固定篮底面直径为7.5cm，轴向长度为12cm。圆盘形磁石的底面直径为3cm。螺旋桨的叶片直径为6cm，螺旋桨中间设有一个突出的顶部平台，顶部平台直径3cm。
应用本发明清洗氧化铝微孔陶瓷零件的过程如下：
步骤1，将氧化铝微孔陶瓷零件置于固定篮，然后通过圆盘形磁石将整个固 定篮吸附在螺旋桨的顶部平台上，螺旋桨转轴顶端的半球与内壳体内腔底部的半球形凹面组成可转动连接。盖好密封盖，将适量的无水乙醇加入到注液口；
步骤2，调节超声波发生器频率为30kHz，调节调速器流速为1500ml/min，稳定工作7-10min后，关闭超声波发生器和调速器。用力向上提手柄，并往前或往后运动4-6cm，松开手柄。再一次按上述频率与流速稳定工作7-10min；
步骤3，重新更换无水乙醇后，调节超声波发生器频率为20kHz，调节调速器流速为2500ml/min，稳定工作10-15min后，关闭超声波发生器和调速器。用力向上提手柄，并往前或往后运动4-6cm，松开手柄。再一次按上述频率与流速稳定工作10-15min；
步骤4，掰开密封盖卡扣，打开密封盖，取出固定篮，室温条件下10-20min后，氧化铝微孔陶瓷零件表面和内部的无水乙醇即完全挥发。
应用本清洗装置能对氧化铝微孔陶瓷零件进行有效清洗，特别是对微小的通孔内的可溶性污物有很好的清洗效果，对盲孔的清洗效果相对略差。
以上所述仅为本申请的优选实施例而已，并不用于限制本申请，对于本领域的技术人员来说，本申请可以有各种更改和变化。凡在本申请的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本申请的保护范围之内。

Claims (10)

  1. 自转位清洗装置，其特征在于，由外壳体、内壳体、工件转位系统、超声波清洁系统和流体灌注系统组成；
    由外壳体、内壳体、工件转位系统、超声波清洁系统和流体灌注系统组成；
    在所述的外壳体内沿着水平方向设有一个内壳体，所述的内壳体内部形成一个圆柱形空腔，内壳体的一端设有与其可拆卸连接的密封盖，另一端封闭；
    所述的工件转位系统设置在所述的空腔里，其用于固定待清洗的清洗件，并利用流体动能实现清洗件的自旋转；
    所述的超声波清洁系统向内壳体的清洗液提供机械能，从而在液体内部产生微小气泡，这些气泡通过持续振动和不断爆裂，将附着在清洗件表面的残留树脂剥离；
    所述的流体灌注系统一方面为清洗件提供自旋转的动力，另一方面不断的将清洗液输送到清洗件内部，实现清洗后，清洗液运出。
  2. 如权利要求1所述的自转位清洗装置，其特征在于，所述内壳体的前、后两端分别设有与流体灌注系统液体相连的进口与出口，其外表面的上、下、左、右分别设有4条振子贴附轨道，所述振子贴附轨道为平面；且在内壳体后端面有一个半球形凹面。
  3. 如权利要求1所述的自转位清洗装置，其特征在于，所述工件转位系统包括圆柱形固定篮、圆盘形磁石和螺旋桨；所述的圆柱形固定蓝设置在内壳体的内腔里，其一端设有与其可拆卸连接的篮盖，另一端通过圆盘形磁石吸附在所述螺旋桨的顶部平台上；所述的螺旋桨转轴安装在内壳体的端部，所述的流体灌注系统可以推动螺旋桨转动。
  4. 如权利要求1所述的自转位清洗装置，其特征在于，所述圆盘形磁石的底面直径应在上述圆柱形固定篮底面直径的25％—40％之间。
  5. 如权利要求1所述的自转位清洗装置，其特征在于，所述螺旋桨的叶片直径应在上述圆柱形固定篮底面直径的40％—85％之间，螺旋桨中间设有一个突出的顶部平台，顶部平台直径在上述圆盘形磁石的底面直径的80％—100％之间；螺旋桨转轴顶端为突出的半球形，其与上述内腔后端的半球形凹面组成可转动连接。
  6. 如权利要求1所述的自转位清洗装置，其特征在于，所述超声波清洁系统包括手柄、四个振子、超声波发生器、四个弹簧、内固定环、外固定环、三个滑块、两个连杆、四个杠杆和四个支点；
    所述超声波发生器安装在上述外壳体外侧面；所述的内固定环、外固定环与所述的内壳体同轴安装，依次设置在内壳体的外圈，在所述的内固定环和外固定环之间设有成环状分布的四个杠杆，四个杠杆分别与四个支点相互接触，且四个杠杆通过两个连杆连接成一个圈； 所述的四个振子头部贴合在所述内壳体外表面的四条振子贴附轨道上，所述四个振子的柄部各自穿过一个弹簧，使弹簧位于振子头部和内固定环之间，其中两个振子的柄部末端连接在杠杆上，另外两个振子的柄部末端连接在连杆上；所述的手柄穿过外壳体和外固定环与其中一个连杆相连；所述的3个滑块设置在外固定环的外部，可以沿着设置在外壳体内侧面的滑道滑动。
  7. 如权利要求6所述的自转位清洗装置，其特征在于，所述内固定环上设有4个小孔，孔的直径大小在4个振子的头部与柄部直径之间。
  8. 如权利要求1所述的自转位清洗装置，其特征在于，所述的外壳体顶部与左右两侧设有3条滑道，外壳体上还设有注液口。
  9. 如权利要求1所述的自转位清洗装置，其特征在于，所述流体灌注系统包括泵、调速器和储液箱；所述的泵与调速器通过导线连接，泵固定在外壳体底部，泵的出口通过管道与所述内壳体前端的液体进口联通；所述储液箱的顶部设有注液口，储液箱中间设有过滤网，过滤网上部的箱壁上设有进口，过滤网下部的箱壁上设有出口；所述储液箱的进口通过管道与所述内壳体后端的液体出口联通，储液箱的出口通过管道与泵的入口联通，储液箱的注液口通过管道与外壳体上的注液口联通。
  10. 一种用于光固化组织工程支架清洗的装置，其特征在于，采用权利要求1-9所述的自转位清洗装置。
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