WO2020038224A1 - 载源体、放疗设备及其控制驱动方法 - Google Patents

载源体、放疗设备及其控制驱动方法 Download PDF

Info

Publication number
WO2020038224A1
WO2020038224A1 PCT/CN2019/099390 CN2019099390W WO2020038224A1 WO 2020038224 A1 WO2020038224 A1 WO 2020038224A1 CN 2019099390 W CN2019099390 W CN 2019099390W WO 2020038224 A1 WO2020038224 A1 WO 2020038224A1
Authority
WO
WIPO (PCT)
Prior art keywords
source
radiation
radiotherapy
imaging device
angle range
Prior art date
Application number
PCT/CN2019/099390
Other languages
English (en)
French (fr)
Inventor
刘海峰
李大梁
Original Assignee
西安大医集团有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 西安大医集团有限公司 filed Critical 西安大医集团有限公司
Priority to EP19851860.7A priority Critical patent/EP3858434A4/en
Priority to JP2021510400A priority patent/JP7315659B2/ja
Publication of WO2020038224A1 publication Critical patent/WO2020038224A1/zh
Priority to US16/805,418 priority patent/US10953244B2/en
Priority to US17/174,778 priority patent/US20210187325A1/en

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/01—Devices for producing movement of radiation source during therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065—Beam adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065—Beam adjustment
    • A61N5/1067—Beam adjustment in real time, i.e. during treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1081—Rotating beam systems with a specific mechanical construction, e.g. gantries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1084—Beam delivery systems for delivering multiple intersecting beams at the same time, e.g. gamma knives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N2005/1018—Intracavitary radiation therapy with multiple channels for guiding radioactive sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1052—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using positron emission tomography [PET] single photon emission computer tomography [SPECT] imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1054—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using a portal imaging system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1055—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1058—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using ultrasound imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1094—Shielding, protecting against radiation

Definitions

  • the present disclosure relates to the field of medical technology, and in particular, to a source carrier, a radiotherapy device, and a control driving method thereof.
  • the radiotherapy equipment used in the related art for treating the head mainly includes a head gamma knife.
  • a natural isotope radioactive source cobalt-60
  • cobalt-60 is used to emit gamma rays
  • the radiation is used to kill the tumor cells.
  • the head gamma knife in the related technology includes 30 or 180 radioactive sources. Multiple radioactive sources emit beams from different directions and focus on a common focus. The radiation dose at the common focus is the largest, and the radiation emitted by each radiation source does little damage to normal tissues or cells, thereby killing tumor cells while protecting normal tissues or cells, and achieving the effect of tumor treatment.
  • the present disclosure provides a source carrier, a radiotherapy apparatus, and a control driving method thereof.
  • the technical solution is as follows:
  • the present disclosure provides a source carrier.
  • the source carrier is provided with a plurality of radiation sources, and an included angle of the plurality of radiation sources in a longitudinal direction is within a preset included angle range.
  • the present disclosure provides a radiotherapy device, the radiotherapy device includes a radiation source device, and the radiation source device includes the source carrier and the collimator provided in the present disclosure.
  • the beams from multiple radiation sources are collimated by the collimator and intersect at a common focus.
  • the present disclosure provides a method for controlling and driving a radiotherapy device.
  • the radiotherapy device is the radiotherapy device according to any one of the disclosure, and the method includes: acquiring at least one beam angle range; The radiotherapy device emits a beam in the beam angle range and intersects at a common focus.
  • FIG. 1 is a schematic structural diagram of a radiotherapy device in a related art according to an embodiment of the present disclosure
  • FIG. 2 is a schematic structural diagram of a source device in a related art according to an embodiment of the present disclosure
  • FIG. 3 is a schematic plan view of a structure of a source body in a related art according to an embodiment of the present disclosure
  • FIG. 4 is a schematic diagram of a source carrier provided by an embodiment of the present disclosure.
  • FIG. 5 is a schematic diagram of another source carrier according to an embodiment of the present disclosure.
  • FIG. 6 is a schematic diagram of another source carrier according to an embodiment of the present disclosure.
  • FIG. 7 is a schematic diagram of a source cassette according to an embodiment of the present disclosure.
  • FIG. 8 is a schematic structural diagram of a common focus located outside an end face of a source body according to an embodiment of the present disclosure
  • FIG. 9 is a schematic diagram of a radiotherapy device according to an embodiment of the present disclosure.
  • FIG. 10 is a schematic diagram of another radiotherapy apparatus according to an embodiment of the present disclosure.
  • FIG. 11 is a schematic diagram of another radiotherapy apparatus according to an embodiment of the present disclosure.
  • FIG. 12 is a schematic diagram of another radiotherapy apparatus according to an embodiment of the present disclosure.
  • FIG. 13 is a schematic diagram of a control driving method according to an embodiment of the present disclosure.
  • FIG. 14 is a schematic diagram of a therapeutic irradiation provided by an embodiment of the present disclosure.
  • 15 is a schematic diagram of another control driving method according to an embodiment of the present disclosure.
  • FIG. 16 is a schematic diagram of another therapeutic irradiation provided by an embodiment of the present disclosure.
  • 17 is a schematic diagram of another control driving method according to an embodiment of the present disclosure.
  • FIG. 18 is a schematic diagram of another control driving method according to an embodiment of the present disclosure.
  • a radiation therapy device that can be used for a head tumor has a structure of radiation treatment of the head tumor as shown in FIGS. 1 and 2.
  • the radiotherapy equipment may include: a radiation source device 01 and a treatment bed 02.
  • the source device 01 may include a source body 011, a shield body 012, and a collimator body 013.
  • a plurality of radiation sources (not labeled in FIG. 2) may be installed in the source body 011.
  • the beams emitted by the plurality of radiation sources pass through a collimation hole (not labeled in FIG. 2) on the collimator 02 and intersect at A common focus, and the common focus is located in the cavity of the source device 01.
  • the treatment bed 02 is used to carry the patient and move it to the inside of the treatment cabin of the radiation source device 01, so that the patient's lesion is located at a common focus for radiotherapy.
  • the shape of the carrier body 011 of the related art radiotherapy equipment is bowl-shaped as shown in FIG. 3.
  • the radioactive sources in the carrier body 011 can be divided into six groups, each group including five sources and a total of 30 radioactive sources.
  • the collimator 013 is provided with a plurality of collimation channels, and the radiation emitted by the radiation source passes through the collimation channels and intersects at a common focus.
  • the collimating body 013 includes six collimating channel groups, and the six collimating channel groups correspond to the positions of the six radiation sources.
  • Each collimating channel group includes four groups, and the collimating holes of one group are filled with solid tungsten rods.
  • the other groups include 5 collimation holes, and the collimation holes of different groups have different sizes.
  • the source carrier 011 and collimator 013 can be driven to rotate with each other to switch collimation holes of different sizes and to switch the source by shielding the radiation source from the collimator, but the size of the six groups of collimation holes is switched and switched. Sources switch at the same time, and one group cannot be controlled individually. Therefore, in the course of treatment, to avoid sensitive tissues and organs (such as the eyes and other important nerves), you can only adjust the gamma angle, that is, avoid the exposure of sensitive tissues and organs by adjusting the elevation angle of the head.
  • the radiotherapy apparatus includes a radiation source device 10.
  • the radiation source device 10 includes a carrier body 11 and a collimator body 12.
  • the carrier body 11 is provided with a plurality of radiation sources 111.
  • the included angles of the plurality of radiation sources 111 in the longitude direction are within a preset included angle range.
  • the beams emitted by the multiple radiation sources on the source body 11 are collimated by the collimator and intersect at a common focus f.
  • the shape of the source body 11 may be bowl-shaped, and its longitude direction is shown by arrow x1 in FIG. 4, which is a direction of longitude 0 ° -360 °.
  • the shape of the carrier body 11 may also be a cylindrical shape as shown in FIG. 5 (the radiotherapy equipment is shown in FIG. 11), and its longitude direction is the direction shown by the arrow x2 in FIG.
  • the size of the two ends of the circular table in FIG. 5 is the same, but of course, the sizes can also be different.
  • the present disclosure does not limit the specific shape of the source carrier, and only uses the examples shown in FIGS. 4 to 5 to illustrate the longitude direction in the present disclosure.
  • the included angle of the radioactive source in the longitude direction is within a preset included angle range, and the maximum included angle of the multiple radioactive sources in the longitude direction is within the preset included angle range.
  • the included angle of the radiation source in the longitudinal direction is an included angle formed with reference to the center of the radiation source. It should be particularly noted here that if the radioactive sources include a row, and the centers of multiple radioactive sources located in the same row are on the same longitude line, the angle of the multiple radioactive sources in the longitude direction is considered to be zero degrees.
  • the preset included angle range is greater than or equal to zero degrees.
  • the radiotherapy equipment provided by the present disclosure may be as shown in FIG. 9 and FIG. 10, and its source body 11 is shown in FIG. 4, and the included angle of the multiple radiation sources 111 in the longitude direction is A.
  • the preset included angle range A may be 5 ° -60 °, that is, 5 ° ⁇ A ⁇ 60 °, and the preset included angle range A may be any included angle in the range of 5 ° -60 °.
  • the preset included angle range A can be 5 °, 8 °, 10 °, 12 °, 18 °, 20 °, 25 °, 30 °, 40 °, 45 °, 50 °, or 60 °.
  • a plurality of radioactive sources are provided on the carrier.
  • the number and arrangement of the radioactive sources are not limited in this disclosure.
  • the number of corresponding radioactive sources may be 20-180, for example, 30 or 180. .
  • the radiotherapy equipment also includes a collimator.
  • the collimation holes on the collimator correspond to the number and arrangement of the radiation sources, so that the beam emitted by the radiation source passes through the collimation holes and intersects at a common focus.
  • a plurality of radioactive sources on a carrier body are distributed within a preset included angle range in a longitude direction, and the radioactive sources can be driven by the carrier body to rotate along a central axis of the radiotherapy device, thereby
  • the radiation source can be turned off when passing through sensitive tissues or organs; the radiation source can be open sourced when passing through normal tissues and organs, so that during the treatment of head tumors, the sensitive tissues and organs such as the eyes can be protected from additional damage .
  • the radiation source device 10 further includes a source carrier driving device for driving the source carrier 11 to rotate around its central axis.
  • the driving device may be a motor, and the source device 10 may also monitor the driving of the motor to obtain the relative position of the source body 11 in real time in order to confirm whether the source is turned on or off.
  • the present disclosure does not specifically limit the driving device of the source body and the position monitoring, and reference may be made to the driving technology in the related technology, and details are not described herein.
  • the patient's tumor can be precisely located at the common focus, so that the radiation kills the tumor cells.
  • the radiation will shift, which is not only harmful to the treatment but also harmful to the patient's health.
  • the common focus of the radiotherapy equipment in the related art is located in the cavity of the source device, it is impossible to monitor whether the patient's head moves during the treatment.
  • a radiotherapy apparatus provided by the present disclosure has a common focus outside the end face of the source device.
  • the common focus f is located outside the end face of the source device, which is beneficial for observing and monitoring whether the patient has moved during treatment.
  • the radiotherapy apparatus provided by the present disclosure further includes an imaging device 30.
  • the imaging device 30 is disposed on one side of the source device 10, and the common focus f is located in the imaging area of the imaging device 30. That is, the tumor of the patient located in the imaging area can be imaged by the imaging device 30, and whether the patient has been displaced or not can be confirmed based on the image.
  • the accuracy of displacement monitoring using images is high.
  • the imaging device 30 in the present disclosure may be an X-ray imaging device, a CT (Computed Tomography) imaging device, an MR (Magnetic Resonance) imaging device, or a DSA (Digital Subtraction Angiography) ;) Any one or more of any one or more of imaging devices, ultrasound imaging devices, or PET (Positron Emission Computed Tomography) imaging devices.
  • the imaging device 30 is an X-ray imaging device.
  • the imaging device 30 may include an X-ray tube 31 and a flat panel detection 32. Alternatively, it may include two X-ray bulbs 31 and two flat-panel detectors 32, and the beams emitted by the two X-ray bulbs 31 intersect.
  • the imaging device 30 may also be a combination of any two or more different imaging devices.
  • the imaging device may be a combination of an X-ray imaging device and a DSA imaging device.
  • the present disclosure does not limit the specific setting manner of the imaging device, and only uses the above as an example for description.
  • the shape of the source body 11 is cylindrical, and the diameters of both ends of the cylindrical source body 11 are the same.
  • the source body 11 and / or the collimator body 12 may also be moved in the direction shown by the central axis of the source device 10 to realize the switching source.
  • the radiotherapy equipment shown in FIG. 12 has a shape of the carrier body 11 of a cylindrical shape, and the diameters of the two ends of the cylindrical source body 11 are different.
  • the source body 11 and / or the collimator body 12 can also be moved in the direction L to realize the switching source. Of course, it can realize the switching source through rotation, which is not limited in this disclosure.
  • the imaging device 30 may be a bulb 31 and a detector plate 32 separately provided with a fixing device to fix the imaging device 30, or the imaging device 30 may also be separately provided with a driving device to drive the bulb 31 and the detector 32.
  • the plate rotates.
  • the imaging device 30 may also be fixedly disposed in the shielding device 40.
  • the specific position and structure of the shielding device are not limited in the present disclosure, and the above description is used as an example for illustration.
  • the radiotherapy apparatus further includes a treatment bed 20 for carrying a patient.
  • a treatment bed 20 for carrying a patient.
  • the present disclosure does not limit the specific structure and movement form of the treatment bed 20, which may be a three-dimensional bed as shown in FIG. 10-12. As shown in Fig. 10, or also a six-bed.
  • the treatment bed 20 can be selectively configured according to the treatment needs, and will not be repeated here.
  • the radiotherapy apparatus provided by the present disclosure is further provided with an anti-sinking component between the collimator body and the source body.
  • the sinking prevention component is a bearing.
  • the radiation source device further includes a shielding device 40.
  • the shielding device 40 is located on one side of the radiation source device 10.
  • the beam emitted by the radiation source 111 passes through the common focus f and is shielded by the shielding device 40.
  • the shielding device 40 is located on one side of the common focus f of the source device 10, and the beam emitted by the radiation source 111 is shielded by the shielding device 40 after passing through the common focus f to avoid treatment. Excessive radiation indoors.
  • the shielding device 40 is a ring-shaped body, all the rays of the radiation source 111 rotating around the central axis are received by the shielding device 40.
  • the shielding device 40 is a shielding block that can be rotated along the central axis of the radiation source device 10 to follow the radiation source 111 to receive the radiation that has passed through the common focus f. It should be noted that, when the treatment bed 20 carries the patient's movement, a channel is opened on the shielding device 40 to facilitate the movement of the treatment bed 40.
  • the present disclosure provides a carrier body.
  • the carrier body 11 is provided with a plurality of radiation sources 111, and an included angle of the plurality of radiation sources 111 in a longitude direction is within a preset included angle range.
  • the included angle of the multiple radiation sources in the longitude direction is within a preset included angle range A.
  • the preset included angle range A may be 5 ° -60 °, that is, 5 ° ⁇ A ⁇ 60 °, and the preset included angle range A may be any included angle in the range of 5 ° -60 °.
  • the preset included angle range A can be 5 °, 8 °, 10 °, 12 °, 18 °, 20 °, 25 °, 30 °, 40 °, 45 °, 50 °, or 60 °.
  • the number and arrangement of the radioactive sources are not limited in the present disclosure, and the number of corresponding radioactive sources can be generally 20-180, for example, 30 or 180. Take only 24 radioactive sources shown in FIG. 4 as an example for illustration.
  • a plurality of radioactive sources are divided into multiple groups in a longitude direction, and an included angle range of two adjacent radioactive sources ranges from 2 ° to 15 °.
  • the included angle of any two adjacent radioactive sources is the same, or the included angle of different adjacent two sets of radioactive sources is different, which is not limited in this disclosure, as shown in FIG. 4 This is just an example.
  • multiple radiation sources are divided into 4 rows, and the included angle of adjacent rows of collimation holes is B (the two illustrated rows are taken as an example) as an example.
  • the included angle B can be 2 °- 15 °, that is, 2 ° ⁇ B ⁇ 15 °, the preset included angle B can be any included angle in the range of 2 ° -15 °.
  • the preset included angle range B can be 2 °, 2.5 °, 3, 5 °, 6 °, 8 °, 10 °, 12 or 15 °.
  • an included angle of a plurality of radiation sources in a latitude direction ranges from 20 ° to 60 °.
  • the source body 11 is provided with a plurality of radiation sources within a preset range C in the longitude direction.
  • the preset included angle range C may be 20 ° -60 °, that is, 20 ° ⁇ C ⁇ 60 °, and the preset included angle range C may be any included angle in the range of 20 ° -60 °.
  • the preset included angle range C can be 20 °, 25 °, 30 °, 38 °, 40 °, 45 °, 50 °, 53 °, or 60 °.
  • the included angle range of any two adjacent radiation sources is 1 ° -10 ° in the latitude direction.
  • the included angles of any two adjacent radioactive sources in the latitudinal direction are the same, or the included angles of any two adjacent radioactive sources in the latitudinal direction are different.
  • FIG. 4 is merely an example illustration. For example, as shown in FIG.
  • the included angle between the two radioactive sources in the latitude direction is D
  • the included angle D may be 1 ° -10 °, that is, 1 ° ⁇ D ⁇ 10 °
  • the preset included angle D can be any included angle in the range of 1 ° -10 °.
  • the preset included angle range D can be 1 °, 2 °, 3, 5 °, 6 °, 8 °, 9 ° or 10 °.
  • the source body 11 shown in FIG. 4 takes the radioactive source including multiple rows in the longitude direction, the radioactive sources located in the same row having the same longitude, and is also divided into multiple rows in the latitude direction, and the radioactive sources located in the same row have the same latitude. Further, as an example to realize non-coplanar irradiation and better protect normal tissues, the source carriers provided in this disclosure have multiple radiation sources in different positions in the latitude direction. That is, each source has a different latitude.
  • the source carrier provided in the present disclosure is provided with a plurality of radiation source holes, and the radiation source is fixedly installed in the radiation source hole.
  • a source box is provided on the source body to match the shape of the source box.
  • the source box can be fixedly installed at the source box, and a plurality of radiation sources are installed on the source box.
  • a plurality of radiation sources 111 are provided on the source box 112, and an active box 113 is provided on the source body 11.
  • the active box 112 and the source box are installed in the source box 113.
  • the position 113 may be a through hole or a blind hole, and a plurality of collimation holes are provided on the source body 11 so that the beam emitted by the radiation source 111 can be emitted through the collimation holes.
  • the disclosure does not limit the shape and structure of the source box and the source box, and only uses the examples shown in FIGS. 6 to 7 as examples for illustration.
  • the source body is further provided with an active case connection portion for fixing the source case located at the source case.
  • the source box is also provided with a connection portion for connecting with the source box.
  • the source carrier and the source box may be connected by screws or by snaps.
  • the connection and fixing method of the source box and the source box is not limited in the present disclosure, and the above example is used as an example for illustration. .
  • the source carrier provided in the present disclosure is further provided with a connecting portion for replacing the source cassette on the source cassette.
  • the connection portion of the source box may be a screw hole, which may be screwed to the source guide rod.
  • the connection portion of the source box and the source guiding rod may be connected by magnet attraction.
  • the disclosure of the connection between the source box and the source guide rod and the replacement method of the source box is not limited in this disclosure, and the above description is used as an example for illustration.
  • the source carrier provided in the present disclosure has a material different from that of the source carrier.
  • the source box may be formed of a tungsten alloy, and the source carrier may be formed of cast iron.
  • the shape of the carrier body 11 is bowl-shaped, and is generally also called a pan shape, a helmet shape, or a hemisphere shape.
  • An example is shown in FIG. 4.
  • the shape of the source body 11 may be cylindrical.
  • An example is shown in FIG. 5, and the diameters of the two ends of the cylindrical shape may be the same or different. In FIG. 5, the diameters of both ends are taken as an example.
  • the carrier may be sheet-shaped.
  • the present disclosure does not specifically limit the specific structural shape of the source carrier, and only uses the above example as an example for illustration.
  • the beams emitted by a plurality of radiation sources intersect at a common focal point after collimation, and the common focus is located on a central axis of the source carrier to facilitate accurate positioning of the radiotherapy equipment.
  • the source body can be fixed or not, or the source body can be driven to rotate 360 ° around the central axis by a rotating device or reciprocally.
  • the source body provided in the present disclosure has a common focal point outside the end surface of the source body.
  • the common focus f is located outside the end surface of the source body 11.
  • the source carrier 11 is set in the entire radiotherapy equipment, as shown in Figs. 10-12, and the common focus f is located outside the end face of the source device. To facilitate the monitoring of patient or tumor movement.
  • the present disclosure provides a method for controlling and driving a radiotherapy device.
  • the radiotherapy device is a radiotherapy device provided by the present disclosure.
  • it may be a radiotherapy device shown in any one of FIGS. 9 to 11.
  • the control driving method includes:
  • Step S1 Acquire at least one beam exit angle range.
  • Step S2 The radiation therapy device is driven to emit a beam in a beam exit angle range and intersect at a common focus.
  • the beam angle range may be an angle range required by the treating physician to include a radiation therapy device for radiation treatment included in a corresponding treatment plan based on the patient's tumor image, and the angle range is an angle driven by the driving device range.
  • the radiation therapy device performs irradiation treatment in the B1 interval, and does not perform irradiation treatment in the A1 interval (the area of A1 includes two eyes).
  • the beam angle range is the driving angle range where the driving device drives the radiation source to irradiate in the B1 interval
  • the protection angle range is the driving angle range where the driving device drives the radiation source to avoid irradiating in the A1 interval.
  • the driving angle range is the rotation angle of the motor.
  • the driving angle range is also exceeded 360 °.
  • the number of rotations and the driving angle range corresponding to different numbers of rotations are calibrated.
  • the beam angle range is a driving angle range for irradiation in the A1 interval and the B1 area, for example, 360 °.
  • the sensitive tissues and organs can be protected by reducing the irradiation time to reduce the dose received by sensitive tissues such as the optic nerve.
  • the disclosure provides a control driving method.
  • the radiotherapy device includes multiple radiation sources, and the source points of the multiple radiation sources are within a preset angle range in the longitude direction.
  • the control driving method includes: obtaining at least one beam angle range, and The radiotherapy equipment is driven to emit a beam in the range of the exit angle and intersect at a common focus, so as to protect sensitive tissues and organs such as the eyes during the treatment of head tumors, and avoid additional injuries.
  • a control driving method provided by the present disclosure further includes:
  • Step S3 Acquire at least one protection angle range. At least one protection angle range is less than 360 °.
  • the beam angle range is driven by the driving device.
  • the driving angle range in which the radiation source performs irradiation in the interval B1 and B2 and the protection angle range is the driving angle range in which the driving device drives the radiation source to avoid irradiation in the interval A1 and A2.
  • Step S4 The radiotherapy equipment is driven so that the beam of the radiation source within the protection angle range is not emitted.
  • the disclosure provides a method for controlling driving.
  • the radiotherapy apparatus includes multiple radiation sources, and the source points of the multiple radiation sources are within a preset angle range in the longitude direction.
  • the method for controlling driving includes: acquiring at least one beam angle range and at least A protective angle range, and drive the radiotherapy equipment to emit a beam in the outgoing angle range and intersect at a common focus, and the beam of a radiation source in the protective angle range is not emitted. Therefore, during the treatment of head tumors, the sensitive tissues and organs such as the eyes can be protected from additional damage.
  • At least one beam angle range is adjacent to one of the protection angle ranges.
  • irradiation treatment is performed in the B1 and B2 sections, and no irradiation treatment is performed in the A1 and A2 sections. Since the B1 section and the A1 section are adjacent, the beam angle range corresponding to the B1 section and the protection angle corresponding to the A1 section are provided. The ranges are adjacent.
  • the number of the beam exit angle ranges is at least two, and the speeds of the radiotherapy apparatuses are different in the beam exit angle ranges.
  • the beam exit angle range corresponding to the B1 interval and the beam exit angle range corresponding to the B2 interval are obtained, and the beam angle range of the radiotherapy equipment in the corresponding B1 interval is obtained.
  • the speed is V1
  • the speed in the range of the exit angle corresponding to the B2 interval is V2, V1 ⁇ V2, so the speed can be used to adjust the irradiation time at different positions and thus the focus dose.
  • the beam angle range is the driving angle range for the irradiation in the A1 area and the B1 area. It may be that the speed in the range of the exit angle corresponding to the B1 section is V1, and the speed in the range of the exit angle corresponding to the A1 section is V2, and V1 ⁇ V2. Even if the speed in the A1 interval is greater than the speed in the B1 interval, the dose received by sensitive tissues in the A1 interval is reduced to protect sensitive tissues and organs.
  • the driving angle range is the rotation angle of the motor, so the driving angle range also exceeds 360 °.
  • the number of rotations is calibrated, and the driving angle range corresponding to different numbers of turns.
  • the speeds of the radiotherapy equipment in at least two beam exit angle ranges are different, and the driving speeds can be different for the same irradiation interval when the number of turns is different.
  • the treatment time for a radiation therapy plan is 2 minutes, and one rotation of the motor drive requires 1 minute.
  • the beam angle in the first circle is the driving speed of the irradiation in the B1 region is V1
  • the second circle The beam angle range is the driving speed of irradiation in the B1 region is V2, and V1 ⁇ V2.
  • the control driving method provided by the present disclosure has two beam exit angle ranges with different speeds adjacent to each other.
  • the control and driving method provided by the present disclosure drives a radiotherapy device to reciprocate within a range of beam angles. For example, if only one beam exit angle range is acquired, the radiotherapy device can reciprocate within the beam exit angle range to increase the dose received by the tumor. Of course, if multiple beam exit angle ranges are acquired, the radiotherapy equipment can also reciprocate within the beam exit angle range to increase the dose received by the tumor.
  • the common focus is outside the end face of the source device.
  • the radiotherapy apparatus further includes an imaging device, and a common focus is located in an imaging area of the imaging device.
  • the driving control method further includes:
  • Step S6 Control the imaging device to acquire an image of the patient.
  • Step S7 Confirm the beam angle range based on the patient's image.
  • the beam exit angle range in step S1 may be the beam exit angle range confirmed by the treating physician based on the patient's image before the radiotherapy, and during the treatment, the beam exit angle range may be confirmed or adjusted based on the acquired image.
  • the radiotherapy equipment shown in FIG. 10-12 further includes an imaging device, and the common focus is located in the imaging area of the imaging device; as shown in FIG. 18, the driving control method further includes:
  • Step S8 Control the imaging device to acquire an image of the patient.
  • Step S9 The protective angle range is confirmed based on the patient's image.
  • the protection angle range in step S3 can be the protection angle range confirmed by the treating physician based on the patient's image before the radiotherapy. During the treatment, the protection angle range can be confirmed or adjusted based on the acquired image.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

本公开是关于一种载源体、放疗设备及其驱动方法，属于医疗技术领域。所述载源体上设置有多个放射源，且所述多个放射源在经度方向的夹角在预设夹角范围内。能够在治疗过程中保护敏感组织器官。

Description

载源体、放疗设备及其控制驱动方法
本公开要求于2018年08月24日提交的申请号为201810975999.X、发明名称为“载源体、放疗设备及其控制驱动方法”的中国专利申请的优先权，其全部内容通过引用结合在本公开中。
技术领域
本公开涉及医疗技术领域，特别涉及一种载源体、放疗设备及其控制驱动方法。
背景技术
随着医疗技术的发展，放射治疗越来越广泛的应用于对肿瘤的治疗。
相关技术中的用于治疗头部的放疗设备主要包括头部伽玛刀，其实利用天然同位素放射源钴-60发出γ射线，利用射线的放射性，经肿瘤细胞杀死。但由于射线同时也会损害正常组织或细胞，因此相关技术中的头部伽玛刀，其包括30或180个放射源，多个放射源从不同方向分别发出射束并聚焦在一个公共焦点，则公共焦点处的射线剂量率最大，而每个放射源发出的射束对正常组织或细胞的损伤较小，从而起到杀死肿瘤细胞同时保护正常组织或细胞的目的，实现肿瘤治疗效果。
发明内容
本公开提供了一种载源体、放疗设备及其控制驱动方法。所述技术方案如下：
一方面，本公开提供了一种载源体，所述载源体上设置有多个放射源，且所述多个放射源在经度方向的夹角在预设夹角范围内。
另一方面，本公开提供了一种放疗设备，所述放疗设备包括射源装置，所述射源装置包括本公开提供的所述的载源体以及准直体，所述载源体上的多个放射源发出的射束经所述准直体进行准直后相交于一个公共焦点。
另一方面，本公开提供了一种放疗设备的控制驱动方法，所述放疗设备为 本公开提供的任一项所述的放疗设备，所述方法包括：获取至少一个出束角度范围；驱动所述放疗设备在所述出束角度范围发出射束并相交于一个公共焦点。
附图说明
为了更清楚地说明本实用新型实施例中的技术方案，下面将对实施例描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本公开的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1是本公开实施例提供的一种相关技术中放疗设备的结构示意图；
图2是本公开实施例提供的一种相关技术中射源装置的结构示意图；
图3是本公开实施例提供的一种相关技术中载源体的俯视结构示意图；
图4是本公开实施例提供的一种载源体示意图；
图5是本公开实施例提供的另一种载源体示意图；
图6是本公开实施例提供的另一种载源体示意图；
图7是本公开实施例提供的一种源匣示意图；
图8是本公开实施例提供的公共焦点位于载源体端面之外的结构示意图；
图9是本公开实施例提供的一种放疗设备示意图；
图10是本公开实施例提供的另一种放疗设备示意图；
图11是本公开实施例提供的另一种放疗设备示意图；
图12是本公开实施例提供的另一种放疗设备示意图；
图13是本公开实施例提供的一种控制驱动方法示意图；
图14是本公开实施例提供的一种治疗照射示意图；
图15是本公开实施例提供的另一种控制驱动方法示意图；
图16是本公开实施例提供的另一种治疗照射示意图；
图17是本公开实施例提供的另一种控制驱动方法示意图；
图18是本公开实施例提供的另一种控制驱动方法示意图。
具体实施方式
为使本公开的目的、技术方案和优点更加清楚，下面将结合附图对本公开实施方式作进一步地详细描述。
相关技术中，可用于头部肿瘤的放疗设备，其头部肿瘤的放射治疗的结构如图1和图2所示。该放疗设备可以包括：射源装置01和治疗床02。射源装置01可以包括：载源体011、屏蔽体012和准直体013。该载源体011内可以安装有多个放射源(图2中未标注)，该多个放射源发出的射束经过准直体02上的准直孔(图2中未标注)后相交于一个公共焦点，且该公共焦点位于射源装置01的腔体内。治疗床02用于承载患者，并将其移动至射源装置01的治疗舱内部，使得患者病灶位于公共焦点处以进行放射治疗。
其中，相关技术中的放疗设备其载源体011的形状为如图3所示为碗状，载源体011中的放射源可以分为六组，每组包括五颗源共计30颗放射源。准直体013上设置有多个准直通道，放射源发出的射线穿过准直通道相交于一个公共焦点。准直体013包括六组准直通道组，六组准直通道组与六组放射源位置对应，每个准直通道组包括四个小组，其中一个小组的准直孔内填充有实心钨棒以实现关源屏蔽，另外的各小组包括5个准直孔，不同小组的准直孔大小不同。
在治疗时，可以驱动载源体011和准直体013相互旋转，来切换不同大小的准直孔以及通过准直体屏蔽放射源来实现开关源，但六组准直孔的大小切换和开关源同时切换，不能单独控制其中的一组。因此，在治疗过程中，要避开敏感组织器官(例如眼睛及其他重要神经等)只能通过调整伽玛角，即通过调节头部的俯仰角以避开敏感组织器官的照射。
本公开提供了一种放疗设备，示例的，参照图9所示，该放疗设备包括射源装置10。该射源装置10包括载源体11以及准直体12，该载源体11上设置有多个放射源111，多个放射源111在经度方向的夹角在预设夹角范围内，载源体11上的多个放射源发出的射束经准直体进行准直后相交于一个公共焦点f。
示例的，如图4所示，载源体11的形状可以为碗状，其经度方向如图4中箭头x1所示，为经度0°-360°的走向方向。载源体11的形状也可以是如图5所示的筒状(放疗设备如图11所示)，其经度方向为图5中箭头x2所示的方向。图5中圆台两端大小一致，当然也可以是大小不同。本公开对于载源体的具体形状不做限定，仅以图4-图5所示的为例，说明本公开中的经度方向。
本公开中，放射源在经度方向的夹角在预设夹角范围内，为多个放射源在经度方向的最大夹角在预设夹角范围内。且本公开中如图4所示，放射源在经 度方向的夹角为以放射源的中心为参考形成的夹角。这里需要特别说明的是，若放射源包括一排，且位于同一排的多个放射源的中心在同一经度线上，则认为该多个放射源在经度方向的夹角为零度，本公开中，预设夹角范围大于等于零度。
示例的，本公开提供的放疗设备可以是如图9和图10所示，则其载源体11如图4所示，多个放射源111在经度方向的夹角为A。示例的，该预设夹角范围A可以是5°-60°，即5°≤A≤60°，预设夹角范围A可以是5°-60°范围内的任意夹角，示例的，预设夹角范围A可以是5°、8°、10°、12°、18°、20°、25°、30°、40°、45°、50°或60°。
载源体上设置有多个放射源，对于放射源的个数和排布方式，本公开不做限定，对应放射源的个数，可以是20-180个，例如可以是30个或180个。仅以图4所示仅以24个放射源为例进行示例说明。放疗设备还包括准直体，准直体上的准直孔与放射源的个数及排布方式对应，以使得放射源发出的射束穿过准直孔后相交于一个公共焦点。
本公开提供的一种放疗设备，载源体上的多个放射源分布在经度方向的预设夹角范围内，则可以通过载源体带动多个放射源沿放疗设备的中心轴旋转，从而可以在经过敏感组织或器官时，将放射源进行关源；在经过正常组织器官时放射源进行开源，从而可以在头部肿瘤治疗过程中，对保护眼睛等敏感组织器官进行保护，避免额外伤害。
本公开提供的一种放疗设备，射源装置10还包括载源体驱动装置，用于驱动载源体11绕其中心轴进行旋转运动。该驱动装置可以是电机，且射源装置10还可以对该电机的驱动进行监控，实时获取载源体11的相对位置，以便确认是否开关源。本公开对载源体驱动装置和位置监测不做具体限定，可以参照相关技术中的驱动技术，这里不做赘述。
在治疗过程中，可以将患者的肿瘤精确的位于公共焦点处，以使得放射线将肿瘤细胞杀死。但若治疗过程中患者发生移动，则放射线发生偏移，不仅不利于治疗还有害于患者健康。由于相关技术中的放疗设备其公共焦点位于射源装置的腔体内，则治疗过程中无法对患者的头部是否移动进行监控。本公开提供的一种放疗设备，公共焦点位于射源装置的端面之外。示例的，如图10、图11所示，公共焦点f位于射源装置的端面之外，则有利于观察和监测患者在治 疗过程中是否发生移动。
本公开提供的放疗设备，示例的，放疗设备还包括成像装置30。该成像装置30设置在射源装置10的一侧，公共焦点f位于成像装置30的成像区域内。即可以通过成像装置30对位于成像区域内的患者肿瘤进行成像，根据图像确认患者是否发生位移。利用图像进行位移监控的精度高。
示例的，本公开中成像装置30可以为X射线成像装置、CT(Computed Tomography，电子计算机断层扫描)成像装置、MR(Magnetic Resonance，磁共振)成像装置、DSA(Digital Subtraction Angiography，数字减影成像；)成像装置、超声成像装置或PET(Positron Emission Computed Tomography，正电子发射型计算机断层显像)成像装置中的任意一种或多种的任意组合。例如成像装置30为X射线成像装置，示例的，如图10所示，其可以包括一个X射线球管31和一个平板探测32。或者也可以是包括两个X射线球管31和两个平板探测32，该两个X射线球管31发出的射束相交。当然，成像装置30也可以是任意两种或多种不同成像装置的组合，例如成像装置可以是X射线成像装置和DSA成像装置的组合。本公开对于成像装置的具体设置方式不做限定，仅以上述为例进行示例说明。
图11所示的放疗设备，其载源体11的形状为筒状，且筒状的载源体11其两端的直径大小相同。图11所示的放疗设备，载源体11和/或准直体12还可以是沿射源装置10中心轴所示的方向移动，来实现开关源。图12所示的放疗设备，其载源体11的形状为筒状，且该筒状的载源体11其两端的直径大小不同。图12所示的放疗设备，载源体11和/或准直体12还可以是沿方向L移动，来实现开关源。当然，其可以通过旋转实现开关源，本公开对此不做限定。
如图10所示，成像装置30可以是单独设置有固定装置以固定的球管31和探测器平板32，或者，成像装置30也可以是单独设置有驱动装置以驱动球管31和探测器32平板旋转。或者，如图11所示，成像装置30也可以是固定设置在屏蔽装置40内，本公开对屏蔽装置的具体位置和结构不做限定仅以上述为例进行示例说明。
此外，放疗设备还包括治疗床20，用于承载患者，如图9-图12所示，本公开对治疗床20的具体结构和运动形式不做限定，其可以是三维床如图10-12所示，或者也可以是六位床如图10所示。治疗床20可以根据治疗需求进行选择 性的配置，这里不做赘述。
本公开提供的放疗设备，在准直体和载源体之间还设置有防下沉组件。参照图9-图10所示，防下沉组件为轴承。
本公开提供的放疗设备，射源装置还包括屏蔽装置40，该屏蔽装置40位于射源装置10的一侧，放射源111发出的射束穿过公共焦点f后被屏蔽装置40屏蔽。示例的，如图10-图12所示，屏蔽装置40位于射源装置10的公共焦点f的一侧，放射源111发出的射束穿过公共焦点f后被屏蔽装置40屏蔽，以避免治疗室内多余的辐射。示例的，屏蔽装置40的形状为环状体，则放射源111绕中心轴旋转一周的射线均被屏蔽装置40接收。或者，屏蔽装置40为屏蔽块，其可沿射源装置10的中心轴旋转，以跟随放射源111旋转接收穿过公共焦点f后的射线。需要说明的是，治疗床20承载患者移动，则屏蔽装置40上开设有通道，以方便治疗床40移动。
以下，对本公开中的载源体进行具体的介绍说明。
本公开提供了一种载源体，该载源体11上设置有多个放射源111，且多个放射源111在经度方向的夹角在预设夹角范围内。示例的，如图4所示，多个放射源在经度方向的夹角在预设夹角范围A内。示例的，该预设夹角范围A可以是5°-60°，即5°≤A≤60°，预设夹角范围A可以是5°-60°范围内的任意夹角，示例的，预设夹角范围A可以是5°、8°、10°、12°、18°、20°、25°、30°、40°、45°、50°或60°。对于放射源的个数和排布方式，本公开不做限定，对应放射源的个数，一般可以是20-180个，例如可以是30个或180个。仅以图4所示仅以24个放射源为例进行示例说明。
示例的，本公开提供的载源体，在经度方向上，多个放射源分为多组，相邻两组放射源的夹角范围为2°-15°。示例的，多组放射源中，任意相邻的两组放射源的夹角均相同，或者，不同的相邻两组放射源的夹角不同，本公开对此不做限定，图4所示仅为一种示例说明。如图4所示，多个放射源分为4排，相邻的排准直孔的夹角为B(图4以示意的两排为例)为例，该夹角B可以是2°-15°，即2°≤B≤15°，预设夹角B可以是2°-15°范围内的任意夹角，示例的，预设夹角范围B可以是2°、2.5°、3、5°、6°、8°、10°、12或15°。
本公开提供的载源体，多个放射源在纬度方向的夹角范围为20°-60°。示例的，如图4所示，载源体11在经度方向的预设范围C内设置有多个放射源。 示例的，该预设夹角范围C可以是20°-60°，即20°≤C≤60°，预设夹角范围C可以是20°-60°范围内的任意夹角，示例的，预设夹角范围C可以是20°、25°、30°、38°、40°、45°、50°、53°或60°。
示例的，本公开提供的载源体，在纬度方向上，任意相邻两个放射源的夹角范围为1°-10°。示例的，多组放射源中，在纬度方向上任意相邻的两组放射源的夹角均相同，或者，在纬度方向上任意相邻的两组放射源的夹角不同，本公开对此不做限定，图4所示仅为一种示例说明。示例的，如图4所示，以其中两个放射源为例，该两个放射源在纬度方向的夹角为D，该夹角D可以是1°-10°，即1°≤D≤10°，预设夹角D可以是1°-10°范围内的任意夹角，示例的，预设夹角范围D可以是1°、2°、3、5°、6°、8°、9°或10°。
图4所示的载源体11，以放射源在经度方向包括多排，位于同一排的放射源经度相同，在纬度方向上也分为多排，位于同一排的放射源纬度相同为例。进一步的，为例实现非共面照射，更好的保护正常组织，本公开提供的载源体，多个放射源在纬度方向上，其位置各不相同。即每个放射源其纬度均不同。
本公开提供的载源体，载源体上设置有多个放射源孔，放射源固定安装在放射源孔内。或者，载源体上设置有与源匣形状相匹配的源匣位，源匣可固定安装在源匣位处，源匣上安装有多个放射源。示例的，如图6、图7所示，源匣112上设置有多个放射源111，载源体11上设置有源匣位113，该源匣位113内安装有源匣112，源匣位113可以是通孔，也可以是盲孔，并在载源体11上设置有多个准直孔，以使得放射源111发出的射束可以穿过该准直孔发出。本公开对于源匣及源匣位的形状和结构不做限定，仅以图6-图7所示的为例进行示例说明。
载源体上还设置有源匣连接部，用于固定位于源匣位处的源匣。同理，源匣上也设置有用于与源匣位连接的连接部。示例的，载源体和源匣可以是通过螺钉连接，也可以是通过卡扣连接，对于源匣与源匣位的连接和固定方式，本公开不做限定，仅以上述为例进行示例说明。
本公开提供的载源体，源匣上还设置有用于取换源匣的连接部。示例的，源匣的连接部可以是螺孔，其可以通过与导源杆螺纹连接。或者，源匣的连接部与导源杆可以是磁铁吸附连接。对于源匣与导源杆的连接，和源匣的取换方式，本公开不做限定，仅以上述为例进行示例说明。
本公开提供的载源体，源匣与载源体的材料不同。示例的，源匣可以是由钨合金形成，载源体可以是由铸铁形成。
本公开提供的载源体，载源体11的形状为碗状，一般也被称为锅状、头盔状或半球状，示例的如图4所示。或者，载源体11的形状可以是筒状，示例的如图5所示，且该筒状的两端的直径可以相同也可以不同，图5中以两端的直径相同为例进行示例。或者，载源体还可以是片状。本公开对载源体的具体结构形状不做具体限定，仅以上述为例进行示例说明。
本公开提供的载源体，多个放射源发出的射束经准直后相交于一个公共焦点，公共焦点位于载源体的中心轴上，以便于放疗设备进行精确摆位。载源体可以是固定不转动，也可以是通过旋转装置驱动载源体绕中心轴360°圆周旋转或往复旋转。
本公开提供的载源体，公共焦点位于载源体的端面之外。示例的，如图8所示，公共焦点f位于载源体11的端面之外。将载源体11设置于整个放疗设备中，如图10-图12所示，公共焦点f位于射源装置的端面之外。以利于实现监控患者或肿瘤的移动。
本公开提供一种放疗设备的控制驱动方法，放疗设备为本公开提供的放疗设备，例如，其可以为图9至图11任一示出的放疗设备。如图13所示，该控制驱动方法包括：
步骤S1：获取至少一个出束角度范围。
步骤S2：驱动放疗设备在出束角度范围发出射束并相交于一个公共焦点。
需要说明的是，由于放疗设备中的驱动装置一般设置预设的零位，在放射治疗过程中以该零位为参考，确认驱动角度范围进行驱动。本公开中，出束角度范围可以是治疗医师根据患者的肿瘤图像，制定的相应的治疗计划中包括的需要放疗设备发出射束进行照射治疗的角度范围，且该角度范围为驱动装置驱动的角度范围。示例的，如图14所示，治疗医师根据患者的肿瘤图像，制定的相应治疗计划中，放疗设备在B1区间进行照射治疗，并在A1区间不进行照射治疗(A1区域为包括两只眼睛的照射区域，避免射线损伤视神经)，则出束角度范围为驱动装置驱动放射源在B1区间进行照射的驱动角度范围，保护角度范围为驱动装置驱动放射源在A1区间避免进行照射的驱动角度范围。放射治疗时仅在B1区间进行照射的驱动角度范围内旋转照射即可，从而可以避免照射眼睛 伤及敏感组织。示例的，驱动角度范围为电机的旋转角。且本公开中，若放疗设备旋转超过360°，则驱动角度范围也超过360°。或者，若放疗设备旋转超过360°，则标定旋转圈数，以及不同圈数对应的驱动角度范围。
当然，放射治疗时也可以是对应A1区域和B1区域均进行旋转照射，则出束角度范围为在A1区间和B1区域进行照射的驱动角度范围，例如可以是360°。此时，可以通过减少照射时间来减少敏感组织如视神经接收的剂量，来保护敏感组织器官。
本公开提供的一种控制驱动方法，放疗设备包括多个放射源，多个放射源的源点在经度方向上的预设角度范围内，控制驱动方法包括：获取至少一个出束角度范围，并驱动放疗设备在出束角度范围发出射束并相交于一个公共焦点，以在头部肿瘤治疗过程中，对保护眼睛等敏感组织器官进行保护，避免额外伤害。
本公开提供的一种控制驱动方法，如图15所示，还包括：
步骤S3：获取至少一个保护角度范围。至少一个保护角度范围小于360°。
如图16所示，放疗设备在B1和B2区间进行照射治疗，并在A1和A2区间不进行照射治疗(A1和A2对应眼睛区域，避免射线损伤视神经)，则出束角度范围为驱动装置驱动放射源在B1和B2区间进行照射的驱动角度范围，保护角度范围为驱动装置驱动放射源在A1和A2区间避免进行照射的驱动角度范围。
步骤S4：驱动放疗设备，使得在保护角度范围内的放射源的射束不发出。
本公开提供的一种控制驱动方法，放疗设备包括多个放射源，多个放射源的源点在经度方向上的预设角度范围内，控制驱动方法包括：获取至少一个出束角度范围以及至少一个保护角度范围，并驱动放疗设备在出束角度范围发出射束并相交于一个公共焦点，在保护角度范围内的放射源的射束不发出。从而可以在头部肿瘤治疗过程中，对保护眼睛等敏感组织器官进行保护，避免额外伤害。
示例的，至少一个出束角度范围和其中一个保护角度范围相邻。如图16所示，B1和B2区间进行照射治疗，并在A1和A2区间不进行照射治疗，由于B1区间和A1区间相邻，则对应B1区间的出束角度范围和对应A1区间的保护角度范围相邻。
本公开提供的控制驱动方法，该出束角度范围的数量为至少两个，至少两个出束角度范围内放疗设备的速度不同。示例的，参照图16所示，B1和B2区间进行照射治疗，则获取对应B1区间的出束角度范围和对应B2区间的出束角度范围，且在放疗设备在对应B1区间的出束角度范围的速度为V1，在对应B2区间的出束角度范围的速度为V2，V1≠V2，从而可以通过速度来调节不同位置处的照射时间进而调节焦点的剂量。
示例的，如图14所示，当放射治疗时对应A1区域和B1区域均进行旋转照射，则出束角度范围为在A1区间和B1区域进行照射的驱动角度范围。可以是的，在对应B1区间的出束角度范围的速度为V1，在对应A1区间的出束角度范围的速度为V2，V1＜V2。即使得在A1区间时的速度大于B1区间的速度，从而减少在A1区间内敏感组织接收的剂量，以保护敏感组织器官。
需要说明的是，本公开中驱动角度范围为电机的旋转角，则驱动角度范围也超过360°。例如电机超过360°，则标定旋转圈数，以及不同圈数对应的驱动角度范围。至少两个出束角度范围内放疗设备的速度不同，可以不同圈数时对应同一照射区间其驱动速度不同。例如，放射治疗计划治疗时间为2min，电机驱动旋转一圈需要1min，如图16所示，则在第一圈出束角度范围为在B1区域进行照射的驱动速度为V1，在第二圈出束角度范围为在B1区域进行照射的驱动速度为V2，V1≠V2。
本公开提供的控制驱动方法，示例的，如上所示的，速度不同的两个出束角度范围相邻。
本公开提供的控制驱动方法，驱动放疗设备在出束角度范围内往复运动。示例的，若仅获取一个出束角度范围，则放疗设备可以在改出束角度范围内往复运动，以增加肿瘤接收的剂量。当然，若获取多个出束角度范围时，放疗设备也可以通过在改出束角度范围内往复运动，来增加肿瘤接收的剂量。
示例的，如图10-12所示的放疗设备，公共焦点位于射源装置的端面之外。放疗设备还包括成像装置，公共焦点位于成像装置的成像区域内。如图17所示，驱动控制方法还包括：
步骤S6：控制成像装置以获取患者的图像。
步骤S7：根据患者的图像，确认出束角度范围。
需要说明的是，步骤S1中的出束角度范围可以是放射治疗前，治疗医师根据患者的图像确认的出束角度范围，治疗过程中，可以根据获取的图像确认或 调整该出束角度范围。
示例的，如图10-12所示的放疗设备，放疗设备还包括成像装置，公共焦点位于成像装置的成像区域内；如图18所示，驱动控制方法还包括：
步骤S8：控制成像装置以获取患者的图像。
步骤S9：根据患者的图像，确认保护角度范围。
同理，步骤S3中的保护角度范围可以是放射治疗前，治疗医师根据患者的图像确认的保护角度范围，治疗过程中，可以根据获取的图像确认或调整该保护角度范围。
以上所述仅为本公开的可选实施例，并不用以限制本公开，凡在本公开的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本公开的保护范围之内。

Claims (26)

  1. 一种载源体，所述载源体上设置有多个放射源，且所述多个放射源在经度方向的夹角在预设夹角范围内。
  2. 根据权利要求1所述的载源体，所述预设夹角范围为5°-60°。
  3. 根据权利要求1所述的载源体，在经度方向上，所述多个放射源分为多组，相邻两组放射源的夹角范围为2°-15°。
  4. 根据权利要求1所述的载源体，所述多个放射源在纬度方向的夹角范围为20°-60°。
  5. 根据权利要求1所述的载源体，在纬度方向上，任意相邻两个放射源的夹角范围为1°-10°。
  6. 根据权利要求1所述的载源体，所述多个放射源在纬度方向其位置各不相同。
  7. 根据权利要求1所述的载源体，所述载源体上设置有多个放射源孔，所述放射源固定安装在所述放射源孔内；或者，
    所述载源体上设置有与源匣形状相匹配的源匣位，所述源匣固定安装在所述源匣位处，所述源匣上安装有所述多个放射源。
  8. 根据权利要求7所述的载源体，所述源匣上还设置有用于取换源匣的连接部。
  9. 根据权利要求7所述的载源体，所述源匣与所述载源体的材料不同。
  10. 根据权利要求1所述的载源体，所述载源体的形状为碗状、筒状或片 状。
  11. 根据权利要求1所述的载源体，所述多个放射源发出的射束经准直后相交于一个公共焦点，所述公共焦点位于所述载源体的中心轴上。
  12. 根据权利要求11所述的载源体，所述载源体绕所述中心轴360°圆周旋转或往复旋转。
  13. 一种放疗设备，所述放疗设备包括射源装置，所述射源装置包括如权利要求1-12任一项所述的载源体以及准直体，所述载源体上的多个放射源发出的射束经所述准直体进行准直后相交于一个公共焦点。
  14. 根据权利要求13所述的放疗设备，所述射源装置还包括载源体驱动装置，用于驱动所述载源体绕所述载源体的中心轴进行旋转运动。
  15. 根据权利要求13所述的放疗设备，所述公共焦点位于所述射源装置的端面之外。
  16. 根据权利要求15所述的放疗设备，所述放疗设备还包括成像装置，所述成像装置设置在所述射源装置的一侧，所述公共焦点位于所述成像装置的成像区域内。
  17. 根据权利要求16所述的放疗设备，所述成像装置包括X射线成像装置、CT成像装置、MR成像装置、DSA成像装置、超声成像装置或PET成像装置中的任意一种或多种。
  18. 根据权利要求15所述的放疗设备，所述射源装置还包括屏蔽装置，所述屏蔽装置位于所述射源装置的一侧，所述放射源发出的射束穿过所述公共焦点后被所述屏蔽装置屏蔽。
  19. 一种放疗设备的控制驱动方法，所述放疗设备为如权利要求13-18任一项所述的放疗设备，所述方法包括：
    获取至少一个出束角度范围；
    驱动所述放疗设备在所述出束角度范围发出射束并相交于一个公共焦点。
  20. 根据权利要求19所述的控制驱动方法，所述方法还包括：
    获取至少一个保护角度范围；
    驱动所述放疗设备，使得在所述保护角度范围内的所述放射源的射束不发出；
    所述至少一个保护角度范围小于360°。
  21. 根据权利要求20所述的控制驱动方法，至少其中一个出束角度范围和其中一个保护角度范围相邻。
  22. 根据权利要求19所述的控制驱动方法，所述出束角度范围的数量为至少两个，至少两个所述出束角度范围内所述放疗设备的速度不同。
  23. 根据权利要求22所述的控制驱动方法，速度不同的两个所述出束角度范围相邻。
  24. 根据权利要求19所述的控制驱动方法，驱动所述放疗设备在所述出束角度范围内往复运动。
  25. 根据权利要求19所述的控制驱动方法，在所述放疗设备还包括成像装置的情况下；所述方法还包括：
    控制所述成像装置以获取患者的图像；
    根据所述患者的图像，确认所述出束角度范围。
  26. 根据权利要求20所述的控制驱动方法，在所述放疗设备还包括成像装置的情况下；所述方法还包括：
    控制所述成像装置以获取患者的图像；
    根据所述患者的图像，确认所述保护角度范围。
PCT/CN2019/099390 2018-08-24 2019-08-06 载源体、放疗设备及其控制驱动方法 WO2020038224A1 (zh)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP19851860.7A EP3858434A4 (en) 2018-08-24 2019-08-06 SUPPORT SOURCE, RADIOTHERAPY EQUIPMENT AND RELATED TRAINING CONTROL PROCESS
JP2021510400A JP7315659B2 (ja) 2018-08-24 2019-08-06 放射線治療装置
US16/805,418 US10953244B2 (en) 2018-08-24 2020-02-28 Control driving method for radiotherapy device
US17/174,778 US20210187325A1 (en) 2018-08-24 2021-02-12 Control driving method for a radiotherapy device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810975999.XA CN109011218A (zh) 2018-08-24 2018-08-24 载源体、放疗设备及其控制驱动方法
CN201810975999.X 2018-08-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US16/805,418 Continuation US10953244B2 (en) 2018-08-24 2020-02-28 Control driving method for radiotherapy device

Publications (1)

Publication Number Publication Date
WO2020038224A1 true WO2020038224A1 (zh) 2020-02-27

Family

ID=64627501

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2019/099390 WO2020038224A1 (zh) 2018-08-24 2019-08-06 载源体、放疗设备及其控制驱动方法

Country Status (5)

Country Link
US (1) US10953244B2 (zh)
EP (1) EP3858434A4 (zh)
JP (1) JP7315659B2 (zh)
CN (1) CN109011218A (zh)
WO (1) WO2020038224A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109011218A (zh) * 2018-08-24 2018-12-18 西安大医集团有限公司 载源体、放疗设备及其控制驱动方法
CN109011217A (zh) * 2018-08-24 2018-12-18 西安大医集团有限公司 一种放射治疗系统及其控制驱动方法
CN109011219B (zh) * 2018-08-24 2023-11-17 西安大医集团股份有限公司 一种放射治疗系统及其控制驱动方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1275410A (zh) * 1999-05-31 2000-12-06 深圳奥沃国际科技发展有限公司 多源放射线全身治疗装置
US6512813B1 (en) * 1999-05-03 2003-01-28 Franz Krispel Rotating stereotactic treatment system
CN1919373A (zh) * 2005-08-25 2007-02-28 惠小兵 放射治疗装置
CN102698374A (zh) * 2012-05-29 2012-10-03 深圳市奥沃医学新技术发展有限公司 一种图像引导放射治疗设备
CN108310684A (zh) * 2018-04-11 2018-07-24 西安大医数码科技有限公司 一种图像引导放射治疗设备
CN109011218A (zh) * 2018-08-24 2018-12-18 西安大医集团有限公司 载源体、放疗设备及其控制驱动方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE453156B (sv) * 1986-04-30 1988-01-18 Elekta Instr Sa Stralkniv innefattande ett stort antal inom ett stralskydd anordnade stralkellor
JPH05200126A (ja) * 1992-01-27 1993-08-10 Hitachi Medical Corp 定位的放射線治療装置
SE506187C2 (sv) 1995-04-05 1997-11-17 Karl Erik Berkestad Anordning vid strålkniv med flyttbar centralkropp
FR2765009B1 (fr) 1997-06-23 1999-09-10 Ch & U Lille Procede de determination automatique de la configuration d'un casque de radiochirurgie stereotaxique sur lequel peut etre adaptee une pluralite de collimateurs focalises sur un isocentre d'irradiation
US7583775B2 (en) * 2002-08-14 2009-09-01 Kabushiki Kaisha Toshiba Concentrated irradiation type radiotherapy apparatus
CN1919372B (zh) 2005-08-25 2011-10-19 深圳市海博科技有限公司 放射治疗装置
CN101195058B (zh) * 2007-11-27 2010-05-26 深圳市海博科技有限公司 多准直体放射治疗装置
CN203647890U (zh) * 2013-12-25 2014-06-18 深圳市奥沃医学新技术发展有限公司 一种用于多源放射治疗设备的局部关源装置
US9155912B2 (en) 2014-01-05 2015-10-13 Xinsheng Cedric Yu Method and system for stereotactic intensity-modulated arc therapy
CN203694431U (zh) * 2014-01-10 2014-07-09 郑晓天 一种数字图像靶点实时跟踪的放疗装置
CN106163613B (zh) 2014-05-22 2019-01-08 深圳市奥沃医学新技术发展有限公司 多源聚焦治疗和适形调强治疗放疗设备及其准直器组合
CN104001269B (zh) * 2014-06-09 2016-07-06 武汉新奥沃医疗新技术有限公司 一种医用放射源装置
CA2976331C (en) 2015-02-11 2024-02-27 Viewray Technologies, Inc. Planning and control for magnetic resonance guided radiation therapy
EP3316965B1 (en) 2015-06-30 2020-05-13 Elekta Ltd. System and method for target tracking using a quality indicator during radiation therapy
US10716952B2 (en) * 2015-08-04 2020-07-21 Our United Corporation Focused radiotherapy apparatus and radiotherapy equipment thereof
CN204864562U (zh) * 2015-08-11 2015-12-16 武汉数码刀医疗有限公司 一种基于机械手移动放射性治疗头的放疗设备
HUE054949T2 (hu) * 2016-07-06 2021-10-28 Univ Clemson Res Foundation Sugárzás-leadó eszközök
CN210131261U (zh) * 2018-08-24 2020-03-10 西安大医集团股份有限公司 载源体及放疗设备

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512813B1 (en) * 1999-05-03 2003-01-28 Franz Krispel Rotating stereotactic treatment system
CN1275410A (zh) * 1999-05-31 2000-12-06 深圳奥沃国际科技发展有限公司 多源放射线全身治疗装置
CN1919373A (zh) * 2005-08-25 2007-02-28 惠小兵 放射治疗装置
CN102698374A (zh) * 2012-05-29 2012-10-03 深圳市奥沃医学新技术发展有限公司 一种图像引导放射治疗设备
CN108310684A (zh) * 2018-04-11 2018-07-24 西安大医数码科技有限公司 一种图像引导放射治疗设备
CN109011218A (zh) * 2018-08-24 2018-12-18 西安大医集团有限公司 载源体、放疗设备及其控制驱动方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3858434A4

Also Published As

Publication number Publication date
EP3858434A1 (en) 2021-08-04
JP2021534884A (ja) 2021-12-16
US10953244B2 (en) 2021-03-23
US20200197731A1 (en) 2020-06-25
EP3858434A4 (en) 2021-10-20
JP7315659B2 (ja) 2023-07-26
CN109011218A (zh) 2018-12-18

Similar Documents

Publication Publication Date Title
JP7330261B2 (ja) 放射線治療装置
US10974072B2 (en) Collimator, radiotherapy device and control driving method thereof
US20210196987A1 (en) Radiotherapy device, control driving method thereof, and radiotherapy system
US5008907A (en) Therapy x-ray scanner
WO2020038224A1 (zh) 载源体、放疗设备及其控制驱动方法
CN113230547B (zh) 一种放射治疗系统
US10953243B2 (en) Radiation treatment device
US20210187325A1 (en) Control driving method for a radiotherapy device
CN209790634U (zh) 准直体及放疗设备
CN210131261U (zh) 载源体及放疗设备
CN210057171U (zh) 一种放射治疗系统
CN107754099A (zh) 磁共振引导的放疗系统
CN209645666U (zh) 一种放射治疗系统
CN209714022U (zh) 一种放射治疗系统
US20240091561A1 (en) Radiation therapy system
JP6667643B2 (ja) 窓口を有するフラットｐｅｔ撮像装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19851860

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2021510400

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2019851860

Country of ref document: EP

Effective date: 20210323