WO2020011130A1

WO2020011130A1 - Combination wave-based therapeutic apparatus and system

Info

Publication number: WO2020011130A1
Application number: PCT/CN2019/095101
Authority: WO
Inventors: 廖利民; 夏术阶; 吕福泰; 林桂亭; 郭应禄; 辛钟成; 郭矛; 林茂繁; 鞠胜; 李�杰; 李洪忠
Original assignee: 北京万孛力医疗器械有限公司
Priority date: 2018-07-09
Filing date: 2019-07-08
Publication date: 2020-01-16
Also published as: CN108720897B; CN108720897A

Abstract

A combination wave-based therapeutic apparatus and system. The combination wave-based therapeutic apparatus comprises: an ultrasonic wave generator unit (10), for generating a therapeutic ultrasonic wave; a shock wave generator unit (20), for generating a therapeutic shock wave; and a combination wave generator (30), coupled to the ultrasonic wave generator unit (10) and the shock wave generator unit (20) respectively, for combining the therapeutic ultrasonic wave with the therapeutic shock wave into a combination wave and applying the combination wave to a site to be treated. The therapeutic apparatus and system can improve the therapeutic effect and reduce the side-effects of therapeutic waves.

Description

Combined wave treatment equipment and treatment system

Cross-reference to related applications

This application is based on an application with a CN application number of 201810741583.1 and an application date of July 9, 2018, and claims its priority. The disclosure of this CN application is incorporated herein as a whole.

Technical field

The present disclosure relates to the field of medical equipment, and in particular, to a combined wave treatment device and a treatment system.

Background technique

Therapeutic ultrasound is an ultrasound that transmits sound energy to target tissues to cause a variety of biological effects. As a form of mechanical energy for pressure waves, therapeutic ultrasound can act on human tissues to form micromechanical pressures and cause biochemical changes at the cellular and molecular level. At present, therapeutic ultrasound is mainly used in medical fields such as tissue healing, nerve / muscle cell regeneration, and promotion of cardiac blood vessel regeneration.

Therapeutic shock wave is a non-invasive treatment method, similar to ultrasound, with pressure effect, tension effect and cavitation effect. The therapeutic shock wave can pass through body fluids and tissues to reach the affected area. According to the different media that it contacts in the human body, such as fat, tendons, ligaments and other soft tissues and skeletal tissues, different mechanical impedances will produce different mechanical stresses at the interface of the tissue. The tensile and compressive stresses on the tissue. In addition, the negative tail wave band of the therapeutic shock wave can also cause cavitation effects, which can be used to unblock occluded fine blood vessels and loosen joint soft tissue adhesion. At present, the therapeutic shock wave is mainly used in stone, analgesia and bone diseases.

Summary of the invention

After research by the inventors, both of the treatment techniques involved in the background have certain limitations and side effects. The sound wave energy of ultrasound may cause local temperature rise, which will adversely affect some enzyme activities in the human body. The cavitation effects of ultrasound and shock waves may damage the integrity of tissue cells and cause damage to the capillaries of the tissue, resulting in bleeding, scarring, and even nerve damage.

In view of this, the present disclosure provides a combined wave treatment device and treatment system, which can improve the treatment effect and reduce the side effects of the treatment wave.

In one aspect of the present disclosure, a combined wave therapy device is provided, including:

Ultrasound generating unit for generating therapeutic ultrasound;

A shock wave generating unit for generating a therapeutic shock wave; and

A combined wave generator, which is respectively coupled with the ultrasonic wave generating unit and the shock wave generating unit, is configured to combine the therapeutic ultrasound wave and the therapeutic shock wave into a combined wave, and apply the combined wave to a site to be treated .

In some embodiments, the therapeutic ultrasound is a low-energy pulsed ultrasound.

In some embodiments, the low-frequency pulsed ultrasound has an ultrasound frequency range of 1 to 2 MHz and a sound intensity range of 0.05 to 3 W / cm ² .

In some embodiments, the ultrasonic energy of the low-energy pulsed ultrasound ranges from 1.5 to 1.7 MHz.

In some embodiments, the therapeutic shock wave is a low intensity extracorporeal shock wave.

In some embodiments, the low-intensity external shock wave has a frequency range of 1 to 6 Hz and an energy range of 0.01 to 0.7 mJ / mm ² .

In some embodiments, the combined wave is a therapeutic shock wave and a therapeutic ultrasound wave combined in a time series.

In some embodiments, the combined wave therapy device further includes:

A controller, which is respectively connected with the ultrasonic wave generating unit, the shock wave generating unit and the combined wave generator, and is used for separately controlling the parameters of the therapeutic ultrasound wave, the parameters of the therapeutic shock wave or the combined wave Adjust the synthesis parameters.

In some embodiments, the combined wave treatment device further includes: a treatment probe operatively coupled with the combined wave generator; and a probe adjustment mechanism operatively coupled with the treatment probe for adjusting The posture of the treatment probe.

In some embodiments, the probe adjustment mechanism includes a robot arm, the treatment probe is installed at an end of the robot arm, and the combined wave treatment device further includes a controller, the controller and the robot arm being respectively Signal connection with the treatment probe is used to control the mechanical arm to drive the treatment probe to the part to be treated.

In some embodiments, the ultrasound generating unit further includes a first adjusting lens, which is connected to the controller signal for adjusting the type of the therapeutic ultrasound output by the ultrasound generating unit to the combined wave generator.

In some embodiments, the shock wave generating unit further includes a second adjustment lens, which is connected to the controller signal for adjusting the type of the therapeutic shock wave output by the shock wave generating unit to the combined wave generator.

In some embodiments, the type includes one of a plane wave, a scattered wave, a focused wave, and a semi-focused wave.

In some embodiments, the combined wave therapy device further includes:

The multimedia playback unit is connected with the controller signal for playing audio and video information of auxiliary use and / or auxiliary treatment.

To achieve the above objective, the present disclosure also provides a treatment system, including:

The aforementioned combined wave therapy device; and

A network cloud platform is communicatively connected with the combined wave therapy device, and is configured to provide a treatment plan to the combined wave therapy device.

In some embodiments, the network cloud platform includes:

An information storage unit for storing patient identification information and medical record information;

A scheme storage unit for storing treatment plans corresponding to different diseases and / or different patients;

The scheme issuing unit is configured to, after confirming the identification information of the patient, issue a corresponding treatment scheme to a combined wave therapy device associated with the patient according to a download request from the patient terminal.

In some embodiments, the treatment plan includes a site to be treated, parameters of the therapeutic ultrasound wave, parameters of the therapeutic shock wave, and synthetic parameters of the combined wave.

Therefore, according to the embodiment of the present disclosure, the therapeutic ultrasonic wave generated by the ultrasonic wave generating unit and the therapeutic shock wave generated by the shock wave generating unit are combined into a combined wave by a combined wave generator, and the combined wave is applied to the site to be treated for treatment. Can fully utilize the respective biological effects of the therapeutic ultrasound and shock wave generating units to improve the treatment effect, and reduce the energy required for the therapeutic ultrasound and the therapeutic shock wave, respectively, and reduce or avoid higher energy therapeutic ultrasound or treatment Side effects of sexual shock waves.

BRIEF DESCRIPTION OF THE DRAWINGS

The drawings described herein are used to provide a further understanding of the present disclosure and constitute a part of the present application. The exemplary embodiments of the present disclosure and the description thereof are used to explain the present disclosure, and do not constitute an improper limitation on the present disclosure. In the drawings:

FIG. 1 is a schematic block diagram of an embodiment of a combined wave therapy device of the present disclosure.

FIG. 2 is a schematic block diagram of another embodiment of a combined wave therapy device of the present disclosure.

FIG. 3 is a schematic block diagram of another embodiment of a combined wave therapy device of the present disclosure.

FIG. 4 is a schematic block diagram of an embodiment of a treatment system of the present disclosure.

FIG. 5 is a comparison chart of the results of the four groups of adipose stem cell proliferation tests.

6 to 8 are comparison results of the four groups of adipose stem cell activation tests at 40 times, 100 times, and 200 times.

Fig. 9 (a) and Fig. 9 (b) are comparison graphs of EdU incorporation rate and cell mitosis rate of four groups of fatty liver cell activation tests, respectively.

detailed description

Various exemplary embodiments of the present disclosure will now be described in detail with reference to the accompanying drawings. The description of the exemplary embodiments is merely illustrative, and in no way serves as any limitation on the present disclosure and its applications or uses. The present disclosure may be implemented in many different forms and is not limited to the embodiments described herein. These embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art. It should be noted that, unless specifically stated otherwise, the relative arrangement of components and steps, the composition of materials, numerical expressions, and numerical values set forth in these examples should be construed as exemplary only, and not as limitations.

The terms “first”, “second”, and the like used in this disclosure do not indicate any order, quantity, or importance, but are only used to distinguish different parts. Words such as "including" or "including" mean that the elements before the word include the elements listed after the word, and do not exclude the possibility that other elements are also covered. "Up", "down", "left", "right", etc. are only used to indicate the relative position relationship. When the absolute position of the described object changes, the relative position relationship may also change accordingly.

In the present disclosure, when it is described that a specific device is located between the first device and the second device, there may or may not be an intervening device between the specific device and the first device or the second device. When it is described that a specific device is connected to another device, the specific device may be directly connected to the other device without an intervening device, or may have an intervening device without being directly connected to the other device.

All terms (including technical or scientific terms) used in this disclosure have the same meanings as understood by those of ordinary skill in the art to which this disclosure belongs, unless specifically defined otherwise. It should also be understood that terms defined in, for example, a general dictionary, should be interpreted to have meanings consistent with their meaning in the context of the relevant technology, and should not be interpreted in an idealized or highly formal sense unless explicitly stated here Defined this way.

Techniques, methods, and equipment known to those of ordinary skill in the relevant field may not be discussed in detail, but where appropriate, the techniques, methods, and equipment should be considered as part of the description.

As shown in FIG. 1, it is a schematic block diagram of an embodiment of a combined wave therapy device of the present disclosure. In this embodiment, the combined wave treatment device includes: an ultrasonic wave generating unit 10, a shock wave generating unit 20, and a combined wave generator 30. The ultrasound generating unit 10 is used to generate a therapeutic ultrasound. In order to obtain a better therapeutic effect, it is preferable to use a low-intensity pulsed ultrasound (LIPUS) for the therapeutic ultrasound. The ultrasonic generation unit 10 may include a piezoelectric ceramic element and a conductive metal sheet. The conductive metal sheet may be arranged overlapping the piezoelectric ceramic element. When the conductive metal sheet is supplied with alternating current, the piezoelectric ceramic element converts the received electric power into mechanical stress, so that the ultrasonic generating unit emits an oscillating wave with a preset ultrasonic frequency.

The shock wave generating unit 20 is used to generate a therapeutic shock wave. In order to obtain a better therapeutic effect, a low-intensity Extracorporeal Shock Wave Therapy (referred to as LI-ESWT) is preferably used for the therapeutic shock wave. By selecting shock wave generating units 20 with different implementation principles, a hydroelectric shock wave, an electromagnetic shock wave, or a pneumatic ballistic shock wave can be generated. Taking a shock wave generating unit that generates a hydroelectric shock wave as an example, a charged high-voltage capacitor is used to send the required discharge energy to a discharge electrode. When the electrode is discharged in a liquid propagation medium, the medium surrounding the electrode explosively evaporates based on the hydroelectric effect , Forms a rapidly expanding plasma, and generates a shock wave in the surrounding liquid.

In order to facilitate the use, the combined wave therapy device may have a host, and the ultrasonic wave generating unit 10 and the shock wave generating unit 20 may be disposed inside the chassis of the host. A combined wave generator 30 is coupled to the ultrasonic wave generating unit 10 and the shock wave generating unit 20, respectively, for combining the therapeutic ultrasound wave and the therapeutic shock wave into a combined wave, and applying the combined wave to a Treatment site. The combined wave generator 30 may be disposed outside the chassis of the host. An interface for user interaction can also be set in the chassis of the host. The combination wave here is embodied by using the same treatment probe to output therapeutic ultrasound and therapeutic shock wave in a specific combination strategy, and the combination strategy may include the respective application time and output timing relationship of the therapeutic ultrasound and therapeutic shock wave (for example, the two are simultaneously , Alternately or alternately according to a certain period).

In this embodiment, the combined ultrasonic wave generated by the ultrasonic wave generating unit and the therapeutic shock wave generated by the shock wave generating unit are combined into a combined wave by a combined wave generator, and the combined wave is applied to the site to be treated for treatment, and the treatment can be fully utilized during the treatment. The respective biological effects of the ultrasonic ultrasound and shock wave generating units improve the treatment effect, and reduce the energy required for the therapeutic ultrasound and the therapeutic shock wave, respectively, and reduce or avoid the side effects of higher energy therapeutic ultrasound or the therapeutic shock wave.

Referring to FIG. 5, the therapeutic effects of therapeutic ultrasound and therapeutic shock waves have been mentioned in the background art, and it is mentioned that when the energy level of ultrasound or shock waves is too high, tissue damage may be caused. The inventors have adopted a combined sequence of low-energy pulsed ultrasound and low-intensity extracorporeal shock waves in exploring better therapeutic effects and fewer side effects.

In order to compare the effects, the inventors divided the fat stem cells into four groups: the control group (ctrl), the low-energy pulsed ultrasound treatment group (LIPUS), the low-intensity external shock wave treatment group (Li-ESWT), and the low-energy pulsed ultrasound and low-frequency Intensity extracorporeal shock wave combined treatment group (US-SW). Among them, the low-energy pulsed ultrasound treatment group used 60 mW / cm ^{2 for} two minutes, and the low-intensity extracorporeal shock wave group used 0.02 mJ / mm ² , 3 Hz, 200 pulses. The low-energy pulsed ultrasound and low-intensity extracorporeal shock wave combined treatment group first adopted Li-ESWT 0.02mJ / mm2, 3Hz, 100pulses, and then given low-energy pulsed ultrasound LIPUS 60mW / cm ^{2 for} one minute.

5-chloromethylfluorescein diacetate (abbreviated as CFDA) has cell membrane permeability, and does not have fluorescence. After passing through the cell membrane into living cells through passive transport, it can be catalyzed by esterase in the cytoplasm to generate carboxyfluorescein succinimidyl ester (CFSE), which can emit strong green fluorescence and cannot penetrate The cell membrane can be kept intact in the cell. 10 uM CFDA was used to label live cells in the culture dish. Then fluorescence microscopy and image analysis. Combining the image shown in Figure 5 and the field of active cells / HPF, it can be seen that compared with the control group, the low-energy pulsed ultrasound treatment group and the low-intensity extracorporeal shock wave group can significantly promote cell proliferation. Increase the number of cells. The use of a half-volume low-energy pulsed ultrasound and a low-intensity extracorporeal shock wave combined treatment group can achieve a stronger effect, reflecting the synergistic effect of therapeutic ultrasound and therapeutic shock waves. Based on the lower applied energy of ultrasound and shock waves, less damage to the tissue when used in combination, and can also achieve a stronger therapeutic effect.

Referring to Figures 6-9 (b), the EdU incorporation test is used to monitor the activation of stem cells by low-energy pulsed ultrasound and low-intensity extracorporeal shock waves, and to detect the expression of the cell division marker H3P. In order to compare the effects, the inventors divided the fat stem cells into four groups: the control group (ctrl), the low-energy pulsed ultrasound treatment group (LIPUS), the low-intensity external shock wave treatment group (Li-ESWT), and the low-energy pulsed ultrasound and low-frequency Intensity extracorporeal shock wave combined treatment group (US-SW). Among them, the low-energy pulsed ultrasound treatment group used 60 mW / cm ^{2 for} two minutes, and the low-intensity extracorporeal shock wave group used 0.02 mJ / mm ² , 3 Hz, 200 pulses. The low-energy pulsed ultrasound and low-intensity extracorporeal shock wave treatment group first adopted Li-ESWT 0.02mJ / mm2, 3Hz, 100pulses, and then given low-energy pulsed ultrasound LIPUS 60mW / cm ^{2 for} one minute. Immediately after treatment, 10 uM EdU was added to each group for 6 hours, and then the conventional cell culture medium was changed. After 24 hours, the expression of EdU and H3P were detected.

Combining the images with different multiples shown in Figures 6-8, it can be seen that compared with the control group, the low-energy pulsed ultrasound treatment group and the low-intensity extracorporeal shock wave group can significantly increase the EdU incorporation rate, which indicates that both Both can promote the S-phase DNA synthesis of stem cells. The use of a half-volume low-energy pulsed ultrasound and a low-intensity extracorporeal shock wave combined treatment group can achieve a stronger effect, reflecting the synergistic effect of therapeutic ultrasound and therapeutic shock waves. In addition, both the low-energy pulsed ultrasound treatment group and the low-intensity extracorporeal shock wave group, or the half-weighted low-energy pulsed ultrasound and low-intensity extracorporeal shock wave treatment group can significantly improve stem cell mitosis. Based on the lower applied energy of ultrasound and shock waves, less damage to the tissue when used in combination, and can also achieve a stronger therapeutic effect.

The above-mentioned combination therapy group's body stimulation method can promote tissue regeneration and healing, and can be used in the treatment of various diseases, such as male erectile dysfunction, incontinence, or postpartum recovery of women.

In the above embodiment, the ultrasonic frequency range of the low-energy pulsed ultrasonic wave is preferably 1 to 2 MHz, and the sound intensity range is 0.05 to 3 W / cm ² . More preferably, the ultrasonic frequency of the low-energy pulsed ultrasonic wave ranges from 1.5 to 1.7 MHz. In this way, low-energy pulsed ultrasound can obtain a better treatment effect with lower energy, and reduce damage to tissues. The low-intensity external shock wave preferably has a frequency range of 1 to 6 Hz and an energy range of 0.01 to 0.7 mJ / mm ² . In this way, low-intensity external ultrasound can obtain a relatively good therapeutic effect with lower energy and reduce tissue damage.

Referring to FIG. 1, when a combined wave generator 30 applies a combined wave to a site to be treated, a combination of a therapeutic shock wave and a therapeutic ultrasound wave along a time series may be used as the combined wave. In other embodiments, the therapeutic shock wave and the therapeutic ultrasound wave may be applied simultaneously or in multiple alternating manners or in different orders according to the needs of the treatment.

As shown in FIG. 2, it is a schematic block diagram of another embodiment of a combined wave therapy device of the present disclosure. Compared with the previous embodiment, the combined wave therapy apparatus further includes a controller 60. The controller 60 may be signal-connected to the ultrasonic generating unit 10, the shock wave generating unit 20, and the combined wave generator 30, respectively, and is configured to separately control parameters of the therapeutic ultrasound wave, parameters of the therapeutic shock wave, or The combined parameters of the combined wave are adjusted. The parameters of the therapeutic ultrasound here may include the ultrasonic frequency range, the sound intensity range, and the type of the therapeutic ultrasound. The parameters of the therapeutic shock wave may include a frequency range, an energy range, and a type of the therapeutic shock wave. The combined parameters of the combined wave may include the duration of the therapeutic ultrasonic wave application, the number of pulses of the therapeutic shock wave, and the timing relationship between the two waves. The controller may take, for example, a microprocessor or processor and a computer-readable medium, logic gate, switch, application specific integrated circuit (computer-readable medium) storing computer-readable program code (e.g., software or firmware) executable by the (micro) processor. Integrated Circuit, such as ASIC), programmable logic controller and embedded microcontroller.

In order to adjust the type of the therapeutic ultrasonic wave, in some embodiments, the ultrasonic wave generating unit 10 may further include a first adjusting lens, which is connected to the controller 60 in a signal and is used to adjust the ultrasonic wave generating unit 10 to the combination. The type of therapeutic ultrasound output by the wave generator 30. Similarly, in order to adjust the type of the therapeutic shock wave, in some embodiments, the shock wave generating unit 20 may further include a second adjustment lens, which is connected to the controller 60 in a signal for adjusting the direction of the shock wave generating unit 20 to The type of therapeutic shock wave output by the combined wave generator 30. The type here may include one of a plane wave, a scattered wave, a focused wave, and a semi-focused wave according to the wave focusing method.

These types of waves are manifestations when waves are emitted, and are mainly distinguished by the density of the waves. Among them, plane waves are all beams that are parallel and do not focus or diverge; scattered waves are beams that diverge and have a lower wave density than plane waves; focused wave beams will converge to a focal point, with more concentrated energy and higher wave density. Large; a semi-focused wave is a wave between a focused wave and a plane wave in terms of wave density. Relatively speaking, the wave density is also between the two, which is larger than a plane wave and smaller than a focused wave. Acoustic lenses can be used as the first adjustment lens and the second adjustment lens to change the focusing degree of the ultrasound or shock wave, and to change the degree of energy concentration by changing different focusing types, thereby obtaining different treatment effects.

In order to facilitate users to use the combined wave therapy device of the present disclosure, the combined wave therapy device may further include a multimedia playback unit 70. The multimedia playback unit 70 is signal-connected to the controller 60 and is configured to play audio and video information for auxiliary use and / or auxiliary therapy. The multimedia playback unit 70 may be a host computer that is communicatively connected to the host of the combined wave therapy device, or a display, a sound card, or the like on the host of the combined wave therapy device, or an earphone or the like that can be worn on the user's head. The multimedia playback unit 70 can inform the user of the use of the combined wave therapy device in the form of audio and video, and provide some music, pictures, or white noise that can assist the therapy during the therapy.

As shown in FIG. 3, it is a schematic block diagram of still another embodiment of a combined wave therapy device of the present disclosure. Compared with the previous embodiments, the combined wave treatment device of this embodiment may further include a treatment probe 40 and a probe adjustment mechanism 50. The treatment probe 40 is operatively coupled with the combined wave generator 30. The probe adjustment mechanism 50 is operatively coupled with the treatment probe 40 and is used to adjust the posture of the treatment probe 40. The user can hold the treatment probe 40 and point the top of the treatment probe 40 at the site to be treated, or adjust the posture of the treatment probe 40, that is, the movement position and the emission angle, through the probe adjustment mechanism 50, so that the treatment probe 40 can be more accurate. It is more convenient to align the treatment site, so as to obtain better treatment results.

The probe adjustment mechanism 50 includes a robot arm, and the treatment probe 40 is installed at an end of the robot arm. The combined wave treatment device further includes a controller 60, which is respectively connected with the robot arm and the treatment. The probe 40 is signal-connected and is used to control the mechanical arm to drive the treatment probe 40 to move to the site to be treated. The controller 60 can control the movement of the robot arm according to a preset command or a command from a user's local or network side, and drive the treatment probe 40 to move between a plurality of parts to be treated.

The above-mentioned combined wave therapy device can be used offline in a user's home or medical place, and can also go online for information interaction with a network cloud platform. As shown in FIG. 4, it is a schematic block diagram of an embodiment of a treatment system of the present disclosure. In this embodiment, the treatment system includes any one of the foregoing combined wave treatment device embodiments and a network cloud platform 80. The network cloud platform 80 is communicatively connected with the combined wave therapy device, and is configured to provide a treatment plan to the combined wave therapy device. The communication connection between the network cloud platform 80 and the combined wave therapy equipment can use any communication standard or protocol, including but not limited to Global System of Mobile (GSM), General Packet Radio Service (General) Packet Radio Service (abbreviated as GPRS), Code Division Multiple Access (abbreviated as CDMA), Wide Band Code Division Multiple Access (abbreviated as WCDMA), etc. Referring to FIG. 4, in some embodiments, the network cloud platform 80 may specifically include: an information storage unit 81, a scheme storage unit 82, and a scheme issuing unit 83. The information storage unit 81 is configured to store patient identification information and medical record information. The scheme storage unit 82 is configured to store treatment schemes corresponding to different diseases and / or different patients. The treatment plan may include a site to be treated, parameters of the therapeutic ultrasound wave, parameters of the therapeutic shock wave, and synthetic parameters of the combined wave. The information storage unit 81 and the scheme storage unit 82 may be implemented by using the same memory or by different memories. The memories include, but are not limited to, ROM / RAM, magnetic disks, and optical disks. The scheme issuing unit 83 is configured to, after confirming the identification information of the patient, issue a corresponding treatment scheme to a combined wave therapy device associated with the patient according to a download request from the patient terminal. The patient terminal can be a mobile or fixed terminal used by the patient himself or it can be an operable interface provided on the combined wave therapy device.

So far, the embodiments of the present disclosure have been described in detail. To avoid obscuring the concept of the present disclosure, some details known in the art are not described. Those skilled in the art can fully understand how to implement the technical solutions disclosed herein based on the above description.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present disclosure and are not limited thereto. Although the present disclosure has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the present invention can still Modifications or equivalent replacements of some of the technical features of the disclosed specific embodiments; without departing from the spirit of the technical solutions of the present disclosure, they should all be covered within the scope of the technical solutions claimed by the present disclosure.

Claims

A combined wave therapy device includes:

An ultrasonic generating unit (10) for generating a therapeutic ultrasonic wave;

A shock wave generating unit (20) for generating a therapeutic shock wave; and

A combined wave generator (30) is coupled to the ultrasonic wave generating unit (10) and the shock wave generating unit (20), respectively, for combining the therapeutic ultrasound wave and the therapeutic shock wave into a combined wave, and The combined wave is applied to the site to be treated.
The combined wave treatment apparatus according to claim 1, wherein the therapeutic ultrasonic wave is a low-energy pulsed ultrasonic wave.
The composition of the wave therapeutic apparatus as claimed in claim 2, wherein the ultrasonic frequency range of the low energy pulse of ultrasonic waves is 1 ~ 2MHz, sound intensity in the range of 0.05 ~ 3W / cm 2.
The combined wave treatment device according to claim 3, wherein an ultrasonic frequency range of the low-energy pulsed ultrasound is 1.5 to 1.7 MHz.
The combined wave treatment device according to claim 1, wherein the therapeutic shock wave is a low-intensity extracorporeal shock wave.
The combined wave treatment device according to claim 5, wherein the low-intensity extracorporeal shock wave has a frequency range of 1 to 6 Hz and an energy range of 0.01 to 0.7 mJ / mm 2 .
The combined wave treatment device according to claim 1, wherein the combined wave is a therapeutic shock wave and a therapeutic ultrasonic wave combined in a time series.
The combined wave therapy device according to claim 7, further comprising:

The controller (60) is signal-connected to the ultrasonic generating unit (10), the shock wave generating unit (20), and the combined wave generator (30), respectively, and is configured to separately control parameters of the therapeutic ultrasonic wave, The parameters of the therapeutic shock wave or the synthesized parameters of the combined wave are adjusted.
The combined wave therapy device according to claim 1, further comprising:

A treatment probe (40) operatively coupled with the combined wave generator (30); and

A probe adjustment mechanism (50) is operatively coupled with the treatment probe (40) and is used to adjust the posture of the treatment probe (40).
The combined wave treatment device according to claim 9, wherein the probe adjustment mechanism (50) includes a robot arm, the treatment probe (40) is installed at an end of the robot arm, and the combined wave treatment device is further A controller (60) is included, and the controller (60) is signal-connected to the robot arm and the treatment probe (40), respectively, for controlling the robot arm to drive the treatment probe (40) to be Treatment site.
The combined wave treatment device according to claim 8, wherein the ultrasound generating unit (10) further comprises a first adjustment lens, which is connected to the controller (60) in a signal for adjusting the ultrasound generating unit (10) ) The type of therapeutic ultrasound output to the combined wave generator (30).
The combined wave treatment device according to claim 8, wherein the shock wave generating unit (20) further comprises a second adjustment lens, which is connected to the controller (60) in a signal for adjusting the shock wave generating unit (20) ) The type of therapeutic shock wave output to the combined wave generator (30).
The combined wave treatment apparatus according to claim 11 or 12, wherein the type includes one of a plane wave, a dispersed wave, a focused wave, and a semi-focused wave.
The combined wave therapy device according to claim 8, further comprising:

The multimedia playback unit (70) is connected to the controller (60) in a signal and is used to play audio and video information for auxiliary use and / or auxiliary treatment.
A treatment system includes:

The combined wave therapy device according to any one of claims 1 to 14; and

A network cloud platform (80) is communicatively connected with the combined wave therapy device, and is configured to provide a treatment plan to the combined wave therapy device.
The treatment system according to claim 15, wherein the network cloud platform (80) comprises:

An information storage unit (81), configured to store patient identification information and medical record information;

A plan storage unit (82), configured to store treatment plans corresponding to different diseases and / or different patients;

A scheme issuing unit (83) is configured to, after confirming the patient's identification information, issue a corresponding therapy scheme to a combined wave therapy device associated with the patient according to a download request from a patient terminal.
The treatment system according to claim 16, wherein the treatment plan includes a site to be treated, parameters of the therapeutic ultrasound wave, parameters of the therapeutic shock wave, and synthesis parameters of the combined wave.