WO2020007780A1 - Procédé et kit pour modifier le résultat d'une intervention de technologie de procréation assistée - Google Patents

Procédé et kit pour modifier le résultat d'une intervention de technologie de procréation assistée Download PDF

Info

Publication number
WO2020007780A1
WO2020007780A1 PCT/EP2019/067564 EP2019067564W WO2020007780A1 WO 2020007780 A1 WO2020007780 A1 WO 2020007780A1 EP 2019067564 W EP2019067564 W EP 2019067564W WO 2020007780 A1 WO2020007780 A1 WO 2020007780A1
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
antibiotic
lactobacillus
procedure
composition
Prior art date
Application number
PCT/EP2019/067564
Other languages
English (en)
Inventor
Jonathan Dennis DE JONGE
Andries Edward Budding
Joep Sebastiaan DE MÖNNINK
Martine Petronella Bos
Original Assignee
Artpred B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artpred B.V. filed Critical Artpred B.V.
Publication of WO2020007780A1 publication Critical patent/WO2020007780A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733Fructosans, e.g. inulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne le domaine de la procréation humaine, en particulier les situations dans lesquelles la procréation humaine est défaillante. La présente invention concerne des procédés fiables et hautement précis permettant de prédire le risque qu'une intervention de technologie de procréation assistée (ART), telle qu'une intervention de fécondation in vitro et une intervention d'injection de sperme intra-cytoplasmique (ICSI) ne conduise pas à une grossesse réussie. L'invention concerne également des moyens et des procédés permettant de prédire la possibilité qu'une intervention de technologie de procréation assistée (ART), telle qu'une intervention de fécondation in vitro et une intervention d'injection de sperme intra-cytoplasmique (ICSI) conduise à une grossesse réussie.
PCT/EP2019/067564 2018-07-02 2019-07-01 Procédé et kit pour modifier le résultat d'une intervention de technologie de procréation assistée WO2020007780A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18181243 2018-07-02
EP18181243.9 2018-07-02

Publications (1)

Publication Number Publication Date
WO2020007780A1 true WO2020007780A1 (fr) 2020-01-09

Family

ID=62842012

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2019/067564 WO2020007780A1 (fr) 2018-07-02 2019-07-01 Procédé et kit pour modifier le résultat d'une intervention de technologie de procréation assistée

Country Status (1)

Country Link
WO (1) WO2020007780A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11278581B2 (en) * 2017-07-07 2022-03-22 Osel, Inc. Use of vaginal Lactobacilli for improving the success rate of in vitro fertilization
CN114959085A (zh) * 2022-08-02 2022-08-30 北京群峰纳源健康科技有限公司 用于预测辅助生殖技术中成功妊娠的标志物及其应用
WO2023090552A1 (fr) * 2021-11-19 2023-05-25 주식회사 지놈앤컴퍼니 Nouvelle souche de lactobacillus plantarum et utilisation associée
WO2024052864A1 (fr) * 2022-09-08 2024-03-14 Freya Biosciences Aps Compositions de microbiote vaginal pour le traitement de l'infertilité

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050276836A1 (en) * 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
WO2009066006A1 (fr) * 2007-11-22 2009-05-28 Bayer Schering Pharma Oy Système d'administration vaginale
US7829079B2 (en) * 2002-03-28 2010-11-09 Christian Hansen A/S Lactobacillus iners for the enhancement of urogenital health
WO2012035028A1 (fr) * 2010-09-14 2012-03-22 Hso Health Care Gmbh Compositions destinées à une administration vaginale et orale de lactobacillus et leurs utilisations
WO2013025095A1 (fr) * 2011-08-12 2013-02-21 Erasmus University Medical Centre Rotterdam Nouveau procédé et nouvelle trousse pour la prédiction du succès d'une fécondation in vitro

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050276836A1 (en) * 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
US7829079B2 (en) * 2002-03-28 2010-11-09 Christian Hansen A/S Lactobacillus iners for the enhancement of urogenital health
WO2009066006A1 (fr) * 2007-11-22 2009-05-28 Bayer Schering Pharma Oy Système d'administration vaginale
WO2012035028A1 (fr) * 2010-09-14 2012-03-22 Hso Health Care Gmbh Compositions destinées à une administration vaginale et orale de lactobacillus et leurs utilisations
WO2013025095A1 (fr) * 2011-08-12 2013-02-21 Erasmus University Medical Centre Rotterdam Nouveau procédé et nouvelle trousse pour la prédiction du succès d'une fécondation in vitro
EP2742359A1 (fr) 2011-08-12 2014-06-18 Erasmus University Medical Center Rotterdam Nouveau procédé et nouvelle trousse pour la prédiction du succès d'une fécondation in vitro

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
ANDERSEN, A. ET AL., HUM. REPROD., vol. 22, 2007, pages 1513 - 1525
BUDDING AEHOOGEWERF MVANDENBROUCKE-GRAULS CMSAVELKOUL PH: "Automated Broad-Range Molecular Detection of Bacteria in Clinical Samples", J CLIN MICROBIOL., vol. 54, no. 4, April 2016 (2016-04-01), pages 934 - 43
BUDDING, E. ET AL., J. CLIN. MICROBIOL., vol. 54, 2016, pages 934 - 943
BURTON ET AL., AEM, vol. 69, 2003, pages 97 - 101
COLLINS ET AL., AEM, vol. 84, 2018, pages e2200
EVERS, J.L., LANCET, vol. 360, 2002, pages 151 - 159
HANS VERSTRAELEN ET AL: "Vaginal lactobacilli, probiotics, and IVF", REPRODUCTIVE BIOMEDICINE ONLINE, vol. 11, no. 6, 1 January 2005 (2005-01-01), AMSTERDAM, NL, pages 674 - 675, XP055533830, ISSN: 1472-6483, DOI: 10.1016/S1472-6483(10)61683-5 *
MACKLAIM ET AL., MICROBIAL ECOLOGY IN HEALTH AND DISEASE, vol. 26, no. 1, 2015, pages 27799
NELSON, S.M.LAWLOR D.A., PLOS MEDICINE, vol. 8, 2011, pages 1 - 10
RAAKEL LUOTO ET AL: "Impact of maternal probiotic-supplemented dietary counselling on pregnancy outcome and prenatal and postnatal growth: a double-blind, placebo-controlled study", BRITISH JOURNAL OF NUTRITION, vol. 103, no. 12, 4 February 2010 (2010-02-04), UK, pages 1792 - 1799, XP055533828, ISSN: 0007-1145, DOI: 10.1017/S0007114509993898 *
SELMAN ET AL., J. ASSISTED REPRODUCTION AND GENETICS, vol. 24, 2007, pages 395 - 399
TEMPLETON, W. ET AL., LANCET, vol. 348, 1996, pages 1402 - 1406

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11278581B2 (en) * 2017-07-07 2022-03-22 Osel, Inc. Use of vaginal Lactobacilli for improving the success rate of in vitro fertilization
WO2023090552A1 (fr) * 2021-11-19 2023-05-25 주식회사 지놈앤컴퍼니 Nouvelle souche de lactobacillus plantarum et utilisation associée
CN114959085A (zh) * 2022-08-02 2022-08-30 北京群峰纳源健康科技有限公司 用于预测辅助生殖技术中成功妊娠的标志物及其应用
WO2024052864A1 (fr) * 2022-09-08 2024-03-14 Freya Biosciences Aps Compositions de microbiote vaginal pour le traitement de l'infertilité

Similar Documents

Publication Publication Date Title
WO2020007780A1 (fr) Procédé et kit pour modifier le résultat d'une intervention de technologie de procréation assistée
Simpson et al. Breastfeeding-associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis ssp. lactis Bb-12
AU2016361583B2 (en) Methods and compositions for reducing vancomycin-resistant enterococci infection or colonization
Donati et al. Vaginal microbial flora and outcome of pregnancy
Genís et al. Pre-calving intravaginal administration of lactic acid bacteria reduces metritis prevalence and regulates blood neutrophil gene expression after calving in dairy cattle
Higgins et al. Transcriptional profiling of cecal gene expression in probiotic-and Salmonella-challenged neonatal chicks
Verdenelli et al. Impact of probiotic SYNBIO® administered by vaginal suppositories in promoting vaginal health of apparently healthy women
Dehkordi et al. Uropathogenic Escherichia coli in the high vaginal swab samples of fertile and infertile women: virulence factors, O-serogroups, and phenotyping and genotyping characterization of antibiotic resistance
Neubauer et al. Effects of clay mineral supplementation on particle-associated and epimural microbiota, and gene expression in the rumen of cows fed high-concentrate diet
TW201408773A (zh) 新穎之卷曲乳酸桿菌(lactobacillus crispatus)菌株
US20210379127A1 (en) Bacterial strains of the lactobacillus paracasei species for use, oral or topical, in the treatment of disorders of the female urogenital tract
JP2022512692A (ja) 泌尿生殖器の酵母感染症および細菌感染症の治療に適したプロバイオティクスなラクトバチルス・クリスパタス株
Koirala et al. Effect of oral consumption of capsules containing Lactobacillus paracasei LPC-S01 on the vaginal microbiota of healthy adult women: a randomized, placebo-controlled, double-blind crossover study
JP2024050778A (ja) 被験体における循環スクシネートのレベルの低下を目的とする標的化介入ならびに前記介入の有効性を判定するためのキットおよび方法
JP7445980B2 (ja) 生殖補助医療手法の転帰の予測方法およびキット
JP6831548B2 (ja) 子宮内細菌叢改善用剤及び組成物、ならびに子宮内細菌叢が改善又は正常化された状態の判定方法
Kim et al. Characteristics of vaginal microbiome in women with pelvic inflammatory disease in Korea
Delucchi et al. Vaginal lactic acid bacteria in healthy and ill bitches and evaluation of in vitro probiotic activity of selected isolates
Mikelsaar et al. Human lactic acid microflora and its role in the welfare of the host
Pytka et al. Microbiome of the women’s genital system
Almeida et al. Lactobacillus crispatus protects against bacterial vaginosis
Fenkci et al. Ovarian abscess due to Brucella melitensis
US20230210923A1 (en) Probiotic for the treatment of infertility and recurrent pregnancy loss
Yang et al. Using PacBio sequencing to investigate the effects of treatment with lactic acid bacteria or antibiotics on cow endometritis
TW202110464A (zh) 抑制具萬古黴素抗藥性腸球菌之益生菌及其組合與其用途

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19740496

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19740496

Country of ref document: EP

Kind code of ref document: A1