WO2019237962A1 - 一种加速渗透的装置 - Google Patents

一种加速渗透的装置 Download PDF

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Publication number
WO2019237962A1
WO2019237962A1 PCT/CN2019/089925 CN2019089925W WO2019237962A1 WO 2019237962 A1 WO2019237962 A1 WO 2019237962A1 CN 2019089925 W CN2019089925 W CN 2019089925W WO 2019237962 A1 WO2019237962 A1 WO 2019237962A1
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injection
section
pipe
spraying
syringe
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PCT/CN2019/089925
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English (en)
French (fr)
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赵冲
张磊
连红可
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西安伊蔓蒂电子科技有限公司
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Priority to AU2019285777A priority Critical patent/AU2019285777A1/en
Publication of WO2019237962A1 publication Critical patent/WO2019237962A1/zh
Priority to AU2020100451A priority patent/AU2020100451A4/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/04—Skin

Definitions

  • the invention belongs to the technical field of beauty equipment, and particularly relates to a device for accelerating penetration.
  • the low-pressure spraying device solves the above disadvantages to a certain extent, but it is also accompanied by new problems, such as low spraying strength, poor atomization effect, and most of the beauty liquid flowing away from the skin surface during use, resulting in waste.
  • An object of the present invention is to provide a device for accelerating penetration to solve the above problems.
  • the present invention adopts the following technical solutions:
  • a device for accelerating penetration includes a spray tube, a push plate, a syringe mounting groove, and a spray device main body; the spray tube is arranged in the spray device main body; a spray device mounting slot is provided on the spray device main body above the spray tube; the syringe mounting slot is close to the spray
  • the end of the tube is provided with a communication tube, which is connected to the injection tube; the other end of the syringe mounting groove is provided with a push plate; one end of the injection tube is an injection outlet and the other end is connected to an external air pump; the injection tube is a venturi tube and an injection tube
  • the middle part is provided with an injection liquid inlet, and the communication pipe is connected with the injection liquid inlet.
  • the injection pipe includes an inlet cylindrical section, a conical constricted section, a cylindrical throat section, a conical diffusion section, and an outlet parallel section; the inlet cylindrical section, the conical constricted section, the cylindrical throat section, the conical diffusion section, and the outlet parallel section are sequentially
  • the connection forms a spray pipe; the spray liquid inlet is arranged on the cylindrical throat section.
  • the length of the inlet cylindrical section is l 1 ; the diameter of the inlet cylindrical section is d 1 ; the included angle of the conical constricted section is ⁇ 1 , the length of the cylindrical throat section is l 2 , and the diameter of the cylindrical throat section is d 2 ; the diameter of the injection liquid inlet is d 4 , the included angle of the conical diffusion section is ⁇ 2 , the length of the parallel exit section is l 3 , and the diameter of the parallel exit section is d 3 ;
  • a syringe containing a spray liquid is arranged in the syringe holding tank, the tail end of the syringe is pushed on the push plate, and the outlet of the syringe is connected with the communication pipe.
  • the injection device main body is provided with an injection switch
  • the injection device main body on the side of the push plate is provided with a push motor
  • the push motor is used to push the push plate to move
  • the injection switch is used to control the start and stop of the push motor.
  • the injection pipe is connected to an external air pump through an injection cable;
  • the injection cable includes an electric wire and an air pipe, and the electric wire and the air pipe are arranged in parallel, the air pipe is connected to the injection pipe, and the electric wire is connected to the driving motor and the injection switch.
  • the present invention has the following technical effects:
  • the invention injects a beauty liquid into a spray tube through a syringe, and simultaneously atomizes the beauty liquid with a high-speed airflow from a trachea, and realizes intermittent spraying of a gas-liquid mixture by controlling the air pump to inject, so as to ensure the initial jet of the gas-liquid mixture each time.
  • the speed is the same, the spray tube is a special size Venturi tube, which further increases the flow rate of the gas from the trachea.
  • the liquid After the cosmetic liquid enters the spray liquid inlet, it is quickly sucked into the spray tube by the negative pressure in the hole, and then collides with the high-speed air flow in the tube, making the beauty
  • the liquid is fully atomized, and the atomized beauty liquid is sprayed from the spray port at a high speed under the action of high-speed airflow, so that it can quickly pass through the skin and achieve the purpose of beauty, thereby achieving needle-free delivery and protecting cells from damage.
  • the invention has the advantages of fast spraying speed, small particles, good atomizing effect, significantly improving the cosmetic effect, extremely high utilization rate of the cosmetic liquid, and greatly reducing waste.
  • FIG. 1 is a schematic structural diagram of the present invention
  • FIG. 2 is a structural diagram of a spray pipe of the present invention
  • FIG. 3 is a fluorescent effect chart of an effect test of spraying atomized particles to the skin tissue
  • 4 to 9 are actual use effect diagrams of the device for accelerating penetration according to the first embodiment.
  • injection tube 1. injection tube; 2. syringe; 3. push plate; 4. injection device body; 5. injection switch; 6. injection cable; 7. inlet cylinder section; 8. cone constriction section; 9. cylinder Throat section; 10, conical diffusion section; 11, parallel section of outlet; 12, jet liquid inlet.
  • the device includes a spray tube 1, a push plate 3, a syringe holding groove, and a spray device body 4; the spray tube 1 is disposed in the spray device body 4; and a spray device body 4 above the spray tube 1 is provided with a syringe A mounting tube is provided at the end of the syringe mounting slot near the spray tube 1 and a communication tube is connected to the spray tube 1.
  • the other end of the syringe mounting slot is provided with a push plate 3; one end of the spray tube 1 is a spray outlet and the other end is connected An external air pump is provided; the spray pipe 1 is a venturi tube, and a spray liquid inlet 12 is provided in the middle of the spray pipe 1, and the communication pipe is connected to the spray liquid inlet 12.
  • the injection pipe 1 includes an inlet cylindrical section 7, a conical constricted section 8, a cylindrical throat section 9, a conical diffusion section 10, and an outlet parallel section 11; the inlet cylindrical section 7, the conical constricted section 8, and a cylinder
  • the throat section 9, the conical diffusion section 10 and the outlet parallel section 11 are sequentially connected to form a spray pipe 1; the spray liquid inlet 12 is arranged on the cylindrical throat section 9.
  • the length of the inlet cylindrical section 7 is l 1 ; the diameter of the inlet cylindrical section 7 is d 1 ; the included angle of the conical constricted section 8 is ⁇ 1 , the length of the cylindrical throat section 9 is l 2 , and the length of the cylindrical throat section 9
  • the caliber is d 2 ; the caliber of the jet liquid inlet 12 is d 4 , the included angle of the conical diffusion section 10 is ⁇ 2 , the length of the outlet parallel section 11 is l 3 , and the diameter of the outlet parallel section 11 is d 3 ;
  • a syringe 2 containing a spray liquid is arranged in the syringe holding tank, the tail end of the syringe 2 is pushed on the push plate 3, and the outlet of the syringe 2 is connected with the communication pipe.
  • the spraying device main body 4 is provided with a spraying switch 5.
  • the spraying device main body 4 on the side of the push plate 3 is provided with a push motor.
  • the pusher motor is used to push the push plate 3 to move.
  • the spray switch 5 is used to control the start and stop of the push motor.
  • the injection pipe 1 is connected to an external air pump through an injection cable 6;
  • the injection cable 6 includes an electric wire and an air pipe, and the electric wire and the air pipe are arranged in parallel, the air pipe is connected to the injection pipe 1, and the electric wire is connected to the driving motor and the injection switch 5.
  • a syringe is used for injection. After the signal during the injection is collected by the data acquisition software, the experimental data of the injection pressure is obtained through software processing.
  • Table 1 is the output pressure corresponding to the input pressure value, confirm the magnitude of the pressure value, and then detect the corresponding sprayed atomized particle size and the effect of the atomized particles reaching the skin tissue under this pressure value. It can be seen from the contents of Table 1 that the device for accelerating penetration of the present invention can achieve a higher output pressure, which is helpful to improve the particle size of the sprayed atomized particles and the effect of the atomized particles reaching the skin tissue.
  • Test method Measured with a laser particle size tester. The data are shown in Table 2.
  • the introduction amounts 1, 2, and 3 are 1 ⁇ L, 2 ⁇ L, and 3 ⁇ L, respectively, and the depths 1, 2, and 3 correspond to 0.5 MPa, 0.65 MPa, and 1 MPa listed in Table 1, respectively.
  • Example 1 The effect of the introduction of fluorescent protein into the accelerated penetration device of Example 1 was examined using a fluorescent labeling method, and the depth of the introduction of the fluorescent protein into the skin tissue was confirmed.
  • Test method Kunming mouse skin tissue samples were numbered, embedded in paraffin, and sectioned and observed under a fluorescent microscope to confirm that the fluorescent protein reached the depth.
  • Test result The fluorescent protein sample fluorescent marker introduced into the accelerated penetration device of Example 1 has penetrated into the dermis layer through the epidermal layer; the fluorescent marker sample was manually applied to distribute the fluorescent marker in the epidermal layer.
  • Test method The device for accelerating penetration of Example 1 can be used to instantly atomize the cosmetic stock solution into particles, and quickly introduce it into the skin fine lines in different parts.
  • the effect of accelerated penetration is shown in Figure 4-9.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
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  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

一种加速渗透的装置包括喷射管(1)、推板(3)、注射器安放槽和喷射装置主体(4)。喷射管（1）设置在喷射装置主体（4）内，喷射管（1）上方的喷射装置主体（4）上设置有注射器安放槽；注射器安放槽靠近喷射管（1）的端部设置有连通管，连通管连接到喷射管（1）；注射器安放槽的另一端设置有推板（3）；喷射管（1）的一端为喷射出口，另一端连接外接气泵；喷射管（1）为文丘里管，喷射管（1）的中部设置有喷射液进口（12），连通管与喷射液进口（12）连接。该装置喷射速度快，颗粒小，雾化效果好，提高美容效果和美容液利用率。

Description

一种加速渗透的装置 技术领域
本发明属于美容设备技术领域，特别涉及一种加速渗透的装置。
背景技术
随着人们生活水平的提高，人们越来越关注美容护肤问题，随之而来的就是美容仪器的不断改进创新。传统美容时，人们往往将美容液直接涂抹于皮肤表层慢慢吸收，或者利用美容仪器将药物注射进皮肤，近几年又出现了利用低气压喷射装置，将气液混合后喷到需要美容的身体部位的方式。由于人体皮肤表皮层的隔绝作用，直接涂抹于皮肤的方式见效缓慢，周期长。传统注射方式又会对细胞造成损伤，容易交叉感染，并且制造、使用成本较高。而低气压喷射装置的出现一定程度上解决了以上缺点，但是也伴随着新的问题出现，如喷射力度低、雾化效果差、使用时大部分美容液从皮肤表面流走造成浪费。
发明内容
本发明的目的在于提供一种加速渗透的装置，以解决上述问题。
为实现上述目的，本发明采用以下技术方案：
一种加速渗透的装置，包括喷射管、推板、注射器安放槽和喷射装置主体；喷射管设置在喷射装置主体内，喷射管上方的喷射装置主体上设置有注射器安放槽，注射器安放槽靠近喷射管的端部设置有连通管，连通管连接到喷射管；注射器安放槽的另一端设置有推板；喷射管的一端为喷射出口，另一端连接外接气泵；喷射管为文丘里管，喷射管的中部设置有喷射液进口，连通管与喷射液进口连接。
进一步的，喷射管包括入口圆筒段、圆锥收缩段、圆筒喉段、圆锥扩散段和出口平行段；入口圆筒段、圆锥收缩段、圆筒喉段、圆锥扩散段和出口平行段依次连接形成喷射管；喷射液进口设置在圆筒喉段上。
进一步的，入口圆筒段的长度为l 1；入口圆筒段的口径为d 1；圆锥收缩段的夹角为α 1，圆筒喉段的长度为l 2，圆筒喉段的口径为d 2；喷射液进口的口径为d 4，圆锥扩散段的夹角为α 2，出口平行段的长度为l 3，出口平行段的口径为d 3；且满足：
d 1＝l 1 l 2＝2d 2 α 1＝21°～25°
α 2＝8°～15° d 2＝1/4d 1～1/2d 1
d 3＝1/2d 1～3/4d 1 d 4＝1/2d 2 l 3＝3l 2～4l 2。
进一步的，注射器安放槽内设置装有喷射液的注射器，注射器的尾端顶在推板上，注射器的出口与连通管连接。
进一步的，喷射装置主体上设置有喷射开关，推板侧面的喷射装置主体内设置有推动电机，推动电机用于推动推板运动，喷射开关用于控制推动电机的启停。
进一步的，喷射管通过喷射线缆连接外接气泵；喷射线缆包括电线和气管，电线和气管并行设置，气管连接喷射管，电线连接推动电机和喷射开关。
与现有技术相比，本发明有以下技术效果：
本发明通过注射器向喷射管注射美容液，同时来自气管的高速气流将美容液雾化，并通过控制气泵喷气，实现间歇性的喷射气液混合物，以保证每次喷射出的气液混合物的初速度一致，喷射管为特殊尺寸的文丘里管，进一步增加气管过来的气体的流速，美容液进入喷射液进口后被孔内的负压快速吸入喷射管，然后与管内高速气流发生碰撞，使得美容液充分雾化，被雾化后的美容液在高速气流的作用下从喷射口高速喷出，从而能够快速穿过皮肤，达到美容目的，以此实现无针投递，保护细胞不受损伤，本发明喷射速度快，颗粒小，雾化效果好，显著提高美容效果，美容液利用率极高，大大减少浪费。
附图说明
图1为本发明结构示意图；
图2为本发明喷射管结构图；
图3为雾化颗粒喷射到达皮肤组织的效果测试的荧光效果图；
图4-图9为实施例1的加速渗透的装置的实际使用效果图。
其中：1、喷射管；2、注射器；3、推板；4、喷射装置主体；5、喷射开关；6、喷射线缆；7、入口圆筒段；8、圆锥收缩段；9、圆筒喉段；10、圆锥扩散段；11、出口平行段；12、喷射液进口。
具体实施方式
以下结合附图对本发明进一步说明：
实施例1
本实施例提供了一种加速渗透的装置。如图1所示，该装置包括喷射管1、推板3、注射器安放槽和喷射装置主体4；喷射管1设置在喷射装置主体4内，喷射管1上方的喷射装置主体4上设置有注射器安放槽，注射器安放槽靠近喷射管1的端部设置有连通管，连通管连接到喷射管1；注射器安放槽的另一端设置有推板3；喷射管1的一端为 喷射出口，另一端连接外接气泵；喷射管1为文丘里管，喷射管1的中部设置有喷射液进口12，连通管与喷射液进口12连接。
如图2所示，喷射管1包括入口圆筒段7、圆锥收缩段8、圆筒喉段9、圆锥扩散段10和出口平行段11；入口圆筒段7、圆锥收缩段8、圆筒喉段9、圆锥扩散段10和出口平行段11依次连接形成喷射管1；喷射液进口12设置在圆筒喉段9上。
入口圆筒段7的长度为l 1；入口圆筒段7的口径为d 1；圆锥收缩段8的夹角为α 1，圆筒喉段9的长度为l 2，圆筒喉段9的口径为d 2；喷射液进口12的口径为d 4，圆锥扩散段10的夹角为α 2，出口平行段11的长度为l 3，出口平行段11的口径为d 3；且满足：
d 1＝l 1 l 2＝2d 2 α 1＝21°～25°
α 2＝8°～15° d 2＝1/4d 1～1/2d 1
d 3＝1/2d 1～3/4d 1 d 4＝1/2d 2 l 3＝3l 2～4l 2。
注射器安放槽内设置装有喷射液的注射器2，注射器2的尾端顶在推板3上，注射器2的出口与连通管连接。
喷射装置主体4上设置有喷射开关5，推板3侧面的喷射装置主体4内设置有推动电机，推动电机用于推动推板3运动，喷射开关5用于控制推动电机的启停。
喷射管1通过喷射线缆6连接外接气泵；喷射线缆6包括电线和气管，电线和气管并行设置，气管连接喷射管1，电线连接推动电机和喷射开关5。
喷射压力测试
测试方法：
使用注射器进行喷射，喷射时的信号经数据采集软件采集后，通过软件处理得到喷射压力的实验数据。
实验数据如表1所示。
表1(单位：MPa)
Figure PCTCN2019089925-appb-000001
Figure PCTCN2019089925-appb-000002
表1为输入压力值对应下的输出压力，确认压力值的大小，进而检测在此压力值下对应喷射雾化颗粒粒度及雾化颗粒到达皮肤组织的效果。由表1的内容可以看出：本发明的加速渗透的装置能够实现较高的输出压力，有助于提高喷射雾化颗粒粒度及雾化颗粒到达皮肤组织的效果。
喷射雾化颗粒粒度测试
测试方法：用激光粒度测试仪测量，数据如表2所示。
表2
Figure PCTCN2019089925-appb-000003
其中，导入量1、2、3分别为1μL、2μL、3μL，深度1、2、3分别对应表1中所列举的0.5MPa、0.65MPa、1MPa。
根据表2的数据可以看出：在0-30μm范围内，雾化颗粒占比超过82％，在50μm以下的范围内，雾化颗粒占比约91％，这说明喷射雾化颗粒效果非常明显。
雾化颗粒喷射到达皮肤组织的效果
使用荧光标记法检测实施例1的加速渗透的装置导入荧光蛋白的效果，确认荧光蛋白导入皮肤组织的深度。
测试方法：分别对昆明小鼠皮肤组织样本进行编号，经石蜡包埋，切片后经过荧光显微镜观察，确认样本荧光蛋白到达深度。
测试数据：如图3所示。
测试结果：实施例1的加速渗透的装置导入荧光蛋白样本荧光标记物已透过表皮层进入真皮层；手工涂抹荧光蛋白样本荧光标记物分布于表皮层。
此测试可有效证明，本发明的加速渗透的装置可瞬间快速喷射，速度快，雾化效果好，可显著提高美容效果，美容液利用率极高，大大减少浪费。
实际使用效果测试：
测试方法：使用实施例1的加速渗透的装置，可将美容原液瞬间雾化成颗粒，快速导入不同部位的皮肤细纹处，在加速渗透的作用下效果如图4‐图9所示。
由图4‐图9可以看出：由于雾化成了细小颗粒，实际使用效果良好，而且对美容原液的利用率极高，减少了浪费。

Claims (6)

  1. 一种加速渗透的装置，其特征在于，包括喷射管(1)、推板(3)、注射器安放槽和喷射装置主体(4)；喷射管(1)设置在喷射装置主体(4)内，喷射管(1)上方的喷射装置主体(4)上设置有注射器安放槽，注射器安放槽靠近喷射管(1)的端部设置有连通管，连通管连接到喷射管(1)；注射器安放槽的另一端设置有推板(3)；喷射管(1)的一端为喷射出口，另一端连接外接气泵；喷射管(1)为文丘里管，喷射管(1)的中部设置有喷射液进口(12)，连通管与喷射液进口(12)连接。
  2. 根据权利要求1所述的一种加速渗透的装置，其特征在于，喷射管(1)包括入口圆筒段(7)、圆锥收缩段(8)、圆筒喉段(9)、圆锥扩散段(10)和出口平行段(11)；入口圆筒段(7)、圆锥收缩段(8)、圆筒喉段(9)、圆锥扩散段(10)和出口平行段(11)依次连接形成喷射管(1)；喷射液进口(12)设置在圆筒喉段(9)上。
  3. 根据权利要求2所述的一种加速渗透的装置，其特征在于，入口圆筒段(7)的长度为l 1；入口圆筒段(7)的口径为d 1；圆锥收缩段(8)的夹角为α 1，圆筒喉段(9)的长度为l 2，圆筒喉段(9)的口径为d 2；喷射液进口(12)的口径为d 4，圆锥扩散段(10)的夹角为α 2，出口平行段(11)的长度为l 3，出口平行段(11)的口径为d 3；且满足：
    d 1＝l 1 l 2＝2d 2 α 1＝21°～25°
    α 2＝8°～15° d 2＝1/4d 1～1/2d 1
    d 3＝1/2d 1～3/4d 1 d 4＝1/2d 2 l 3＝3l 2～4l 2。
  4. 根据权利要求1所述的一种加速渗透的装置，其特征在于，注射器安放槽内设置装有喷射液的注射器(2)，注射器(2)的尾端顶在推板(3)上，注射器(2)的出口与连通管连接。
  5. 根据权利要求1所述的一种加速渗透的装置，其特征在于，喷射装置主体(4)上设置有喷射开关(5)，推板(3)侧面的喷射装置主体(4)内设置有推动电机，推动电机用于推动推板(3)运动，喷射开关(5)用于控制推动电机的启停。
  6. 根据权利要求5所述的一种加速渗透的装置，其特征在于，喷射管(1)通过喷射线缆(6)连接外接气泵；喷射线缆(6)包括电线和气管，电线和气管并行设置，气管连接喷射管(1)，电线连接推动电机和喷射开关(5)。
PCT/CN2019/089925 2018-06-14 2019-06-04 一种加速渗透的装置 WO2019237962A1 (zh)

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WO2022198372A1 (zh) * 2021-03-22 2022-09-29 上海茜茜纤美美容科技有限公司 一种无针水光注射装置
CN116237176B (zh) * 2023-05-11 2023-07-25 四川工程职业技术学院 一种内置雾化装置及内置雾化方法

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