WO2019222836A1 - Vaporisateur d'inhalation doté d'un distributeur d'aliquote pour distribuer des doses mesurées - Google Patents

Vaporisateur d'inhalation doté d'un distributeur d'aliquote pour distribuer des doses mesurées Download PDF

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Publication number
WO2019222836A1
WO2019222836A1 PCT/CA2019/050670 CA2019050670W WO2019222836A1 WO 2019222836 A1 WO2019222836 A1 WO 2019222836A1 CA 2019050670 W CA2019050670 W CA 2019050670W WO 2019222836 A1 WO2019222836 A1 WO 2019222836A1
Authority
WO
WIPO (PCT)
Prior art keywords
heater
volatile liquid
inhalation
reservoir
user
Prior art date
Application number
PCT/CA2019/050670
Other languages
English (en)
Inventor
Michael WILLINSKY
Original Assignee
Willinsky Michael
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Willinsky Michael filed Critical Willinsky Michael
Publication of WO2019222836A1 publication Critical patent/WO2019222836A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/48—Fluid transfer means, e.g. pumps
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/48—Fluid transfer means, e.g. pumps
    • A24F40/485—Valves; Apertures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0402—Special features for tracheal tubes not otherwise provided for
    • A61M16/042—Special features for tracheal tubes not otherwise provided for with separate conduits for in-and expiration gas, e.g. for limited dead volume
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/362—General characteristics of the apparatus related to heating or cooling by gas flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

Definitions

  • the invention relates to an inhalation vaporizer for delivering a vaporised inhalant comprising an aliquot dispenser for delivering metered, discrete, incremental aliquots of volatile liquid from a volatile liquid reservoir to a liquid vaporizing heater.
  • An electronic cigarette or e-cigarette is typically a hand-held electronic device for emulating more conventional smoking of dried plant materials: although in use it is associated with heating a liquid constituency comprising, for example, propylene glycol, glycerine, and flavorings and often but not always, nicotine.
  • a liquid constituency comprising, for example, propylene glycol, glycerine, and flavorings and often but not always, nicotine.
  • Some such liquids have been reported to include cannabinoids: Int J Environ Res Public Health. 2015 Aug; 12(8): 9988-10008 Published online 2015 Aug 21 , ⁇ -Cigarettes: A Review of New Trends in Cannabis Use”, Giroud et al.
  • This heating facilitates the generation of an aerosol, (e.g. a "vapor”), that the user inhales - a practice sometimes referred to as“vaping”.
  • aerosol e.g. a "vapor”
  • vaping a practice sometimes referred to as“vaping”.
  • the practice is in at least some quarters, thought to be safer than the conventional smoking of tobacco cigarettes - and indeed its use has been reported as an aid for facilitating“quitting” by smokers of dried tobacco products. While broader insights into health and social implications of recreational vaping are still under investigation, these vaping practices have been associated with adverse effects include throat and mouth irritation, vomiting, nausea, and coughing.
  • Nicotine poisoning may engender tachycardia, diaphoresis, nausea, and vomiting, and late signs include hypotension, seizures, respiratory depression, and death.
  • E-cigarettes have been listed as drug delivery devices in several countries because they contain nicotine, and their advertising has been restricted until safety and efficacy clinical trials are conclusive. There is clearly a need to address leakage as well as dosing issues.
  • a vapor delivery device for delivering a metered dosage of a liquid constituency contained within a container having a valve adapted on selective actuation, to deliver instances of said dosage (consider volume/concentration) for conversion into a vapor - especially through thermal conversion (e.g. a liquid-vaporizing heater), for administration through inhalation modalities (e.g. oral, nasal).
  • thermal conversion e.g. a liquid-vaporizing heater
  • each instance of actuation results in a predetermined volumetric delivery.
  • an inhalation vaporizer for delivering a vaporised inhalant comprising an aliquot dispenser for delivering metered, discrete, incremental aliquots of volatile liquid from a volatile liquid reservoir to a liquid vaporizing heater.
  • the aliquot dispenser typically comprises one of a valve or a pump (with a pump being preferred to the extent that it can function as a positive displacement device for facilitating metered doses - whereas a valve operation may rely on time from opening to closing as a proxy for the volume metered thereby).
  • the liquid vaporizing heater is a non-pyrolytic heater - and while other options exist, the heater in this case will typically be a thermal heater and especially an electrical resistance heater.
  • aspects of the present invention may include user-powered, mechanically actuated aliquot dispensers - which offer some advantage in their simplicity and the fact that the dispensing operation does not rely on on-board power reserves that can then be allocated to, for example, the operation of an electric heater.
  • Syringe or lever pumps may be examples of such user powered aliquot dispensers.
  • the dispenser is a user operated electrical solenoid actuated, aliquot dispenser.
  • a piston or screw type mechanism may be operated by such a solenoid. In any case, these tend to be more discrete in their operation than a user-powered device.
  • the reservoir may be a propellant pressurized reservoir, and a valve-opening/closing-operations actuator is provided to operate the valve for delivering the metered, discrete, incremental aliquots of volatile liquid from the propellant pressurized volatile liquid reservoir to the vaporizing heater.
  • the dispenser includes a pump
  • a pump actuating mechanism is provided to operate the pump for delivering metered, discrete, incremental aliquots of volatile liquid from said propellant pressurized volatile liquid reservoir to said vaporizing heater.
  • positive displacement pump action can result in more accurate and consistent metering of the does.
  • the vaporizer includes a heater actuator for actuating the heater’s vaporization of delivered metered, discrete, incremental aliquots of volatile liquid.
  • a user-activated switch for closing an electrical circuit connecting a battery and the resistive heater element are contemplated for this purpose.
  • Figure 1 is an elevated top view of a“vape-pen” embodiment of the present invention.
  • Figure 2 is an elevated cross-sectional view through the“vape-pen” depicted in Figure 1 ;
  • Figure 3 is an exploded view of that same“vape-pen” embodiment
  • Figure 4 is an exploded view of a reservoir and associated dosing pump useful in embodiments of the present invention.
  • Figure 5 is an elevated side view of a mouth piece depicting a lateral venturi ambient air inlet
  • Figure 6 is an exploded view including a heater useful in aspects of the present invention.
  • an inhalation vaporizer 1 comprising a housing 2.
  • Housing 2 provides accommodation for a power supply 3 (e.g. a battery 3a); and a volatile liquid reservoir 4 adapted on actuation thereof to facilitate discharge of incremental aliquots of the volatile liquid.
  • a power supply 3 e.g. a battery 3a
  • a volatile liquid reservoir 4 adapted on actuation thereof to facilitate discharge of incremental aliquots of the volatile liquid.
  • Housing 2 further includes: at least one air inlet 5 for admitting air drawn by user inhalation; at least one air outlet 6 through which a user inhales; and, an interconnecting channel 7 for accommodating air flow between inlet 5 and outlet 6.
  • housing 2 includes within it, a discharge actuator 8 for actuating discharge of incremental aliquots of said volatile liquid, from the reservoir 4, to facilitate delivery thereof to heater 9.
  • Heater 9 is adapted to receive metered, discrete, incremental aliquots of volatile liquid from volatile liquid reservoir 4, and to be operable by heater actuator 10 for actuating heater 9 to vaporize delivered incremental aliquots of said volatile liquid, discharged from reservoir 4.
  • the interconnecting channel 7 is adapted to mix air drawn by user inhalation with vaporized liquid from heater 9, to pass a mixture of air and vaporized liquid to outlet 6 for user inhalation.
  • Outlet 6 includes a mouthpiece 1 1 adapted to be engaged by a user’s mouth, and in the embodiments depicted in the appended drawings, includes at least one venturi 12 for admitting additional ambient air, drawn by user inhalation, into the mouthpiece for mixing with the volatile liquid air mixture drawn from channel 7.
  • venturi 12 accomplishes both of these in proportion to the particular effort expended by the user in any given instance of a draw on the vaporizer 1.
  • heater actuator 10 mouthpiece 1 1 at least one venturi 12

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un vaporisateur d'inhalation ayant un boîtier contenant une alimentation électrique et un réservoir de liquide volatil conçu pour l'actionnement de celui-ci pour faciliter la décharge d'aliquotes incrémentielles de liquide volatil ; une entrée d'air pour faire entrer de l'air aspiré par l'inhalation de l'utilisateur et une sortie d'air à travers laquelle un utilisateur inhale et un canal d'interconnexion pour recevoir un flux d'air entre celles-ci ; un actionneur de décharge pour actionner la décharge d'aliquotes incrémentielles de liquide volatil pour la distribution à un dispositif de chauffage ; le dispositif de chauffage étant conçu pour recevoir celui-ci et, avec un actionneur de dispositif de chauffage actionnant le dispositif de chauffage, pour vaporiser les aliquotes de liquide volatil distribuées déchargées du réservoir.
PCT/CA2019/050670 2018-05-21 2019-05-17 Vaporisateur d'inhalation doté d'un distributeur d'aliquote pour distribuer des doses mesurées WO2019222836A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862674135P 2018-05-21 2018-05-21
US62/674,135 2018-05-21

Publications (1)

Publication Number Publication Date
WO2019222836A1 true WO2019222836A1 (fr) 2019-11-28

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ID=68616204

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2019/050670 WO2019222836A1 (fr) 2018-05-21 2019-05-17 Vaporisateur d'inhalation doté d'un distributeur d'aliquote pour distribuer des doses mesurées

Country Status (1)

Country Link
WO (1) WO2019222836A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060196518A1 (en) * 2003-04-29 2006-09-07 Lik Hon Flameless electronic atomizing cigarette
US20090114220A1 (en) * 2006-04-13 2009-05-07 Boehringer Ingelheim International Gmbh Medicament dispensing device, medicament magazine therefor and method of removing a medicament from a medicament chamber
KR101544594B1 (ko) * 2013-12-04 2015-08-13 주식회사 제씨테크 액상 에센스 수동 공급을 위한 피스톤식 전자 담배
US20160213065A1 (en) * 2015-01-22 2016-07-28 Fontem Holdings 1 B.V. Electronic vaporization devices

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060196518A1 (en) * 2003-04-29 2006-09-07 Lik Hon Flameless electronic atomizing cigarette
US20090114220A1 (en) * 2006-04-13 2009-05-07 Boehringer Ingelheim International Gmbh Medicament dispensing device, medicament magazine therefor and method of removing a medicament from a medicament chamber
KR101544594B1 (ko) * 2013-12-04 2015-08-13 주식회사 제씨테크 액상 에센스 수동 공급을 위한 피스톤식 전자 담배
US20160213065A1 (en) * 2015-01-22 2016-07-28 Fontem Holdings 1 B.V. Electronic vaporization devices

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