WO2019212426A3 - Delayed release dexketoprofen composition - Google Patents

Delayed release dexketoprofen composition Download PDF

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Publication number
WO2019212426A3
WO2019212426A3 PCT/TR2018/000129 TR2018000129W WO2019212426A3 WO 2019212426 A3 WO2019212426 A3 WO 2019212426A3 TR 2018000129 W TR2018000129 W TR 2018000129W WO 2019212426 A3 WO2019212426 A3 WO 2019212426A3
Authority
WO
WIPO (PCT)
Prior art keywords
dexketoprofen
composition
delayed release
mialgia
migrane
Prior art date
Application number
PCT/TR2018/000129
Other languages
French (fr)
Other versions
WO2019212426A2 (en
Inventor
Mahmut BILGIÇ
Original Assignee
Neutec Ar-Ge Sanayi Ve Ticaret Anonim Şirketi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neutec Ar-Ge Sanayi Ve Ticaret Anonim Şirketi filed Critical Neutec Ar-Ge Sanayi Ve Ticaret Anonim Şirketi
Publication of WO2019212426A2 publication Critical patent/WO2019212426A2/en
Publication of WO2019212426A3 publication Critical patent/WO2019212426A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention is related to pharmaceutical compositions comprising dexketoprofen free base and and dexketoprofen trometamol to be used to treat fever, mild and moderate pain, headache, toothache, migrane prophylaxis and mialgia diseases.
PCT/TR2018/000129 2017-12-29 2018-12-28 Delayed release dexketoprofen composition WO2019212426A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2017/23035 2017-12-29
TR2017/23035A TR201723035A2 (en) 2017-12-29 2017-12-29 Dexketoprofen delayed release composition.

Publications (2)

Publication Number Publication Date
WO2019212426A2 WO2019212426A2 (en) 2019-11-07
WO2019212426A3 true WO2019212426A3 (en) 2019-11-28

Family

ID=67900930

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/TR2018/000136 WO2020022976A2 (en) 2017-12-29 2018-12-28 A formulation comprising dexketoprofen
PCT/TR2018/000129 WO2019212426A2 (en) 2017-12-29 2018-12-28 Delayed release dexketoprofen composition

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/TR2018/000136 WO2020022976A2 (en) 2017-12-29 2018-12-28 A formulation comprising dexketoprofen

Country Status (2)

Country Link
TR (2) TR201723035A2 (en)
WO (2) WO2020022976A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230414545A1 (en) * 2020-12-04 2023-12-28 Laboratorios Silanes S.A. De C.V. Fixed combination medicine for the control and management of neuropathic pain
CN115607509B (en) * 2022-10-11 2024-01-30 南京正科医药股份有限公司 Dexketoprofen tromethamine injection and preparation process thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012158127A2 (en) * 2011-05-18 2012-11-22 Mahmut Bilgic Water-soluble formulations comprising dexketoprofen
CN102813638A (en) * 2011-06-07 2012-12-12 贵阳医学院 Preparation method of dexketoprofen trometamol double-layer sustained-release tablets
WO2013022410A2 (en) * 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) * 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623280A (en) * 2008-07-10 2010-01-13 广东肇庆星湖生物科技股份有限公司 Compound sustained release preparation for easing pain and preparation method thereof
ES2394888B1 (en) * 2011-06-15 2013-09-23 Farmalider, S.A. PHARMACEUTICAL FORM OF MODIFIED RELEASE OF DEXKETOPROPHENE AND INHIBITOR OF THE PUMP OF PROTONS AND USE OF THE SAME.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012158127A2 (en) * 2011-05-18 2012-11-22 Mahmut Bilgic Water-soluble formulations comprising dexketoprofen
CN102813638A (en) * 2011-06-07 2012-12-12 贵阳医学院 Preparation method of dexketoprofen trometamol double-layer sustained-release tablets
WO2013022410A2 (en) * 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) * 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BARBANOJ, M. J. ET AL.: "Pharmacokinetics of dexketoprofen trometamol in healthy volunteers after single and repeated oral doses", THE JOURNAL OF CLINICAL PHARMACOLOGY, vol. 38, no. S1, December 1998 (1998-12-01) - 11 October 2017 (2017-10-11), pages 33S - 40S, XP055657910 *

Also Published As

Publication number Publication date
TR201723035A2 (en) 2019-07-22
TR201815617A2 (en) 2019-07-22
WO2020022976A2 (en) 2020-01-30
WO2020022976A3 (en) 2020-03-12
WO2019212426A2 (en) 2019-11-07

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