WO2019146888A1 - Système de ventilation mécanique non invasif pour mesurer des changements de volume d'air dans un poumon et le degré d'obstruction des voies respiratoires et son procédé de fonctionnement - Google Patents

Système de ventilation mécanique non invasif pour mesurer des changements de volume d'air dans un poumon et le degré d'obstruction des voies respiratoires et son procédé de fonctionnement Download PDF

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Publication number
WO2019146888A1
WO2019146888A1 PCT/KR2018/013718 KR2018013718W WO2019146888A1 WO 2019146888 A1 WO2019146888 A1 WO 2019146888A1 KR 2018013718 W KR2018013718 W KR 2018013718W WO 2019146888 A1 WO2019146888 A1 WO 2019146888A1
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Prior art keywords
air
subject
unit
image data
injected
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PCT/KR2018/013718
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English (en)
Korean (ko)
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위헌
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주식회사 바이랩
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0809—Detecting, measuring or recording devices for evaluating the respiratory organs by impedance pneumography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/56—Devices for preventing snoring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/15—Detection of leaks

Definitions

  • the present invention relates to a noninvasive mechanical ventilation system and a method of operating the same. More particularly, the present invention relates to a non-invasive mechanical ventilation system and a method of operating the same. More particularly, the present invention relates to a non-invasive mechanical ventilation system, A noninvasive mechanical ventilation system for measuring changes in air volume of the subject's lungs and the degree of airway obstruction using an EIT (Electrical Impedance Tomography) method, and appropriately controlling the air to be injected into the subject to treat the subject's disease, and And to a method of operation.
  • EIT Electrommpedance Tomography
  • NMV Non-invasive mechanical ventilation
  • Noninvasive mechanical ventilation not only lowers the risk of infection, but also improves patient survival due to respiratory failure.
  • Noninvasive mechanical ventilation can provide precise inhalation and exhalation pressure or tidal volume depending on the subject's degree of ventilation, enhance ventilation per minute of alveolar fibers, or activate destroyed alveolar fibers.
  • Noninvasive mechanical ventilation is used to treat respiratory diseases such as sleep apnea, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and asthma (athma).
  • COPD chronic obstructive pulmonary disease
  • ARDS acute respiratory distress syndrome
  • asthma asthma
  • noninvasive mechanical ventilation can be used to treat nuromuscular diseases such as amyotrophic lateral sclerosis (ALS) and spinal cord injury.
  • nuromuscular diseases such as amyotrophic lateral sclerosis (ALS) and spinal cord injury.
  • sleep apnea includes apnea and hypopnea.
  • Apnea is defined as the period during which the respiratory airflow decreases to less than 10% of the normal breathing air for at least 10 seconds during sleep.
  • Breathing air is reduced to 10 to 70% of the normal respiratory airflow lasts for more than 10 seconds, and at the same time the blood oxygen saturation is reduced by 3 or 4%.
  • Apnea and low respiration during sleep can be divided into central, which occurs without obstructive and respiratory effort, caused by abnormal occlusion or reduced area of the upper airway, although there is a breathing effort.
  • PSG was performed in patients who were admitted to a private laboratory for sleep electroencephalography (EEG), electroogulography (EOG), electromyography (EMG), oronasal air flow, nasal pressure, chest respiratory effort, abdomen respiratory effort, SpO2, It detects ECG (electrocardiography), sleep posture, and movement to detect sleep apnea and hypopnea with sleep state.
  • AHI apnea hypopnea index
  • AHI is a criterion for judging the degree of sleep apnea and deciding whether to treat.
  • HST estimates AHI by measuring several signals during sleep at home, such as nasal pressure, respiratory effort, SpO2, heart rate, sleep posture, and movement.
  • Patients with AHI above a certain level in the diagnosis of sleep apnea using PSG or HST prescribe treatment such as noninvasive ventilation, positive airway pressure (PAP), oral structures or upper gastrointestinal surgery.
  • treatment such as noninvasive ventilation, positive airway pressure (PAP), oral structures or upper gastrointestinal surgery.
  • the PAP used for sleep apnea treatment consists of an air pressure generator that produces airflow with a positive pressure relative to atmospheric pressure, a mask that attaches to both nose and mouth, and a tube that connects them.
  • CPAP continuous PAP raises the output air pressure to a predetermined air pressure and maintains its value, including intake and exhalation. It helps to suck in air when sucking, and to prevent closure of sucking. However, there are many cases where the patient feels uncomfortable due to positive pressure during expiration.
  • APAP automated PAP measures the air pressure and air flow of the mask to vary the output air pressure.
  • BiPAP uses two different output air pressures during exhalation and inspiration.
  • PSG is performed using PAP, and titration process is performed to determine the output air pressure suitable for the patient.
  • APAP is mainly used when PAP is used after HST without separate PSG inspection.
  • BiPAP is used in patients with cardiopulmonary or neurological diseases.
  • the existing APAP measures air pressure and airflow inside the mask and changes the output air pressure in a manner unique to each manufacturer, depending on the value.
  • the air pressure and the air flow of the mask are different from the air pressure and the air flow in the patient airway.
  • Specialist pulmonary function testing devices such as spirometers are equipped with pressure and air flow sensors in the nose and mouth to measure the air pressure and airflow of the airway, but it is difficult to attach these sensors to patients wearing PAP masks.
  • the air when the pulmonary function improvement treatment is performed, the air must be delivered to the patient's lungs with the pressure and the volume of the set air.
  • Sleep apnea is associated with various pathologies such as anatomical structure of the upper respiratory tract, respiratory-related muscle nervous system function, nervous system response to changes in blood oxygen and carbon dioxide concentration due to lack of respiration, It is a complex disease that involves physiological factors.
  • AHI AHI for the diagnosis of sleep apnea makes it difficult to determine the severity and cause of sleep apnea, thus making it difficult to select treatment methods depending on the severity and cause. Therefore, it is difficult to maintain the effect of the sleep apnea treatment.
  • the present invention provides a noninvasive mechanical ventilation system and method of operation that increase the efficiency of noninvasive mechanical ventilation therapy by using existing noninvasive treatment methods and electrical impedance tomography (EIT) methods together.
  • EIT electrical impedance tomography
  • the present invention provides a non-invasive mechanical ventilation system for accurately estimating the amount of air leaked from the inside of a mask by using an electrical impedance tomography method in non-invasive mechanical ventilation treatment, and an operation method thereof.
  • the present invention seeks to provide a non-invasive mechanical ventilation system that accurately estimates the amount of air leaked and actively controls the pressure and volume of air injected in non-invasive mechanical ventilation therapy, and an operation method thereof.
  • the present invention is to provide an EIT data processing apparatus and an operation method thereof for monitoring a lung function based on electrical impedance tomography and generating a control signal for controlling a respiration management apparatus based on monitoring.
  • the present invention provides a non-invasive mechanical ventilation system and a method of operating the same, which are capable of calculating diagnostic parameters of a subject using monitoring of respiratory parameters of a subject collected through a mask and lung function based on electrical impedance tomography.
  • An object of the present invention is to provide a non-invasive mechanical ventilation system and an operation method thereof that accurately estimate the amount of air leaked from a mask in performing a non-invasive treatment method, thereby improving the therapeutic effect of respiratory or neuromuscular diseases.
  • the present invention accurately estimates the amount of air leaked from a mask attached to a subject, and controls one of the volume and pressure of air injected through the mask based on the estimated amount of air, And to provide a non-invasive mechanical ventilation system and an operation method thereof.
  • the present invention provides a non-invasive mechanical ventilation system for calculating diagnostic parameters for lung function diagnosis based on respiratory parameters and electrical impedance tomography, and a method of operation thereof.
  • a non-invasive mechanical ventilation system includes a plurality of electrodes attached to at least one site of a subject's chest and neck, the current and / or current from the at least one site via the attached plurality of electrodes
  • a respiration management unit for injecting air into the subject and collecting respiratory parameters of the subject based on the air to be injected, and a respiration management unit for collecting respiratory parameters of the subject based on the air to be injected,
  • a control unit for comparing the generated image data to estimate a leakage amount of the injected air and controlling the injected air.
  • the EIT data processing unit controls the selection of at least one pair of electrodes at the plurality of attached electrodes, supplies current to the selected pair of electrodes, controls the selection of the unselected electrodes Measure the voltage through the unselected electrodes, and generate image data of an internal change of at least one of the chest and the neck based on the injected air in real time.
  • the controller may monitor any one of a change in lung volume inside air volume and a change in degree of occlusion of the airway based on the generated image data.
  • the respiration management unit may include a mask in contact with one of the nose and mouth of the subject and a tube connected to the mask, injecting the air into the subject through the mask, The air pressure in the mask and the respiratory parameters associated with the airflow signal upon air injection.
  • the controller may calculate the airflow signal by differentiating the monitored lung internal air volume change, and compare the airflow signal in the mask with the calculated airflow signal to estimate the leakage amount .
  • the controller when the estimated leakage amount is larger than the reference value, the controller increases one of volume and pressure of air injected through the mask, and when the estimated leakage amount is smaller than the reference value, It is possible to maintain one of the volume and the pressure of air injected through the mask.
  • an output value corresponding to one of the maintained volume and pressure is output to the respiratory management unit, , And controls the injected air to be maintained according to the determined output power value.
  • control unit controls the respiration management unit to maintain the injected air at the determined output proper value, and when the state change of the subject is detected through the EIT data processing unit, It is possible to control the air to be injected through the mask in accordance with the state change.
  • the respiratory management unit includes an external device connection unit to which at least one of an air cleaner, a replaceable water bottle, and a replaceable oxygen can is connected, and the respiratory management unit is connected to the air cleaner And controls the humidity of the air to be supplied to the subject by spraying the water supplied from the replaceable water bottle through the external device connection unit and controls the humidity of the exchangeable oxygen Oxygen supplied from the can can be supplied to the subject.
  • the respiration management unit may provide a specific substance included in the supplied moisture to the subject through the external device connection unit.
  • An electrode unit formed with a plurality of electrodes for current injection and voltage sensing and attached to at least one of a chest and a neck of a subject; a current supplying unit for supplying a current to at least one selected electrode pair of the plurality of electrodes;
  • An image data generation unit and a respiration management device for measuring a voltage through electrodes and generating image data of at least one of the chest and the neck, the apparatus comprising: a signal delivery unit for delivering signal data extracted from the image data and the image data; Section.
  • the EIT data processing apparatus receives the respiration parameter according to the respiration of the subject from the respiration management apparatus, and compares the received respiration parameter and one of the generated image data and the extracted signal data Further comprising a control signal generator for generating a control signal for controlling the air to be injected by the respiratory management apparatus based on the estimated air leakage amount estimating unit for estimating an air leakage amount of the air injected into the subject,
  • the signal transmission unit may transmit the generated control signal to the respiration management apparatus.
  • the image data generation unit controls the selection of at least one electrode pair in the plurality of electrodes, controls the selection of the unselected electrodes, Image data of an internal change of at least one of the chest and the neck can be generated in real time.
  • the air leakage amount estimating unit may monitor any one of a lung internal air volume change and a change in the degree of closing of the airway based on one of the generated image data and the signal data extracted from the image data,
  • the air flow signal is calculated by differentiating the monitored lung internal air volume change, and the leakage amount can be estimated by comparing the air flow signal in the mask included in the respiration management apparatus with the calculated air flow signal.
  • the control signal generation unit may generate a control signal for controlling the respiration management apparatus to increase one of volume and pressure of air injected through the mask And generate a control signal for controlling the respiration management apparatus to maintain one of a volume and a pressure of air injected through the mask when the estimated leakage amount is smaller than the reference value.
  • the signal transmission unit transmits the biometric data of the subject based on one of the image data and the signal data to at least one of the plurality of object Internet apparatuses and the user terminal apparatus using the cloud computing service, .
  • a non-invasive mechanical ventilation system includes a plurality of electrodes attached to at least one site of a subject's chest and neck, and a voltage from the at least one site via the plurality of attached electrodes
  • a respiration management unit for injecting air into the subject and collecting respiratory parameters of the subject based on the air to be injected, and a control unit for controlling the respiration management unit, And a controller for calculating the lung function diagnosis parameter using the breathing parameter.
  • the control unit changes the pressure and volume of the air injected by the respiratory management unit
  • the EIT data processing unit modifies the volume and volume of air in the lungs of the chest according to the changed pressure and volume
  • the respiration management unit generates image data on a change in an airflow and an upper airway area change of the neck
  • the respiration management unit collects changes in breathing parameters of the subject based on the air injected according to the changed pressure and volume
  • the control unit may calculate the lung function diagnosis parameter by using the generated image data and the change of the respiration parameter.
  • the lung function diagnosis parameter may include at least one of the respiratory system gain or sensitivity of the subject, the subject's respiratory insufficiency arousal threshold, and the upper airway responsiveness .
  • a method of operating a non-invasive mechanical ventilation system comprising: injecting air into a subject in a respiratory management unit; injecting air into the subject in at least one of the chest and neck of the subject; Measuring the voltage from the at least one region through electrodes of the subject to generate image data of the subject's subject; and in the respiration management unit, collecting respiratory parameters of the subject based on the injected air, Estimating a leak amount of the injected air by comparing the collected respiration parameter and the generated image data; and controlling the injected air based on one of the image data, the breath parameter, and the estimated leak amount And a step of controlling.
  • an operation method of an EIT data processing apparatus includes a step of supplying an electric current to at least one selected electrode pair among a plurality of electrodes attached to at least one part of a chest and neck of a subject And generating image data for at least one of the chest and the neck by measuring a voltage through unselected electrodes among the plurality of electrodes in the image data generation unit, The method comprising the steps of: receiving a breathing parameter of a subject, comparing the received breathing parameter and the generated image data to estimate a leakage amount of air injected into the subject, and in the control signal generation unit, Generating a control signal for controlling the air injected by the device, In, it can include the delivery of the control signal generated by the respiratory care equipment.
  • a method of operating a non-invasive mechanical ventilation system comprising the steps of injecting air into a subject in a respiratory management unit, and injecting air into the subject in at least one of the chest and neck of the subject Measuring a voltage from the at least one site through an electrode to generate image data of the inside of the subject; collecting respiratory parameters of the subject based on the injected air in a respiration management unit; And calculating the lung function diagnosis parameter using the generated image data and the collected respiration parameter.
  • the present invention can increase the efficiency of non-invasive mechanical ventilation therapy by using a combination of existing non-invasive treatment methods and electrical impedance tomography (EIT) methods.
  • EIT electrical impedance tomography
  • the present invention can accurately estimate the amount of air leaked from the inside of a mask by using an electrical impedance tomography method in non-invasive mechanical ventilation treatment.
  • the present invention can actively control the pressure and volume of air injected in non-invasive mechanical ventilation therapy by accurately estimating the amount of air leaked.
  • the present invention can monitor the lung function based on electrical impedance tomography and generate a control signal for controlling the respiration management apparatus based on the monitoring.
  • the present invention can calculate the subject's diagnostic parameters using the breathing parameters of the subject collected through the mask and the monitoring of lung function based on electrical impedance tomography.
  • the amount of air leaking from the mask can be accurately estimated to improve the therapeutic effect of respiratory diseases or muscular system diseases.
  • the present invention accurately estimates the amount of air leaked from a mask attached to a subject, and controls one of the volume and pressure of air injected through the mask based on the estimated amount of air, Can be improved.
  • the present invention can produce diagnostic parameters for pulmonary function diagnosis based on respiratory parameters collected through a mask and electrical impedance tomography.
  • FIG. 1 is a view for explaining an embodiment of a non-invasive mechanical ventilation system according to an embodiment of the present invention.
  • FIG. 2 is a diagram illustrating components of a non-invasive mechanical ventilation system according to an embodiment of the present invention.
  • 3A is a view for explaining components of an EIT data processing apparatus according to an embodiment of the present invention.
  • FIG. 3B is a diagram illustrating a connection configuration between an EIT data processing apparatus and a respiration management apparatus according to an embodiment of the present invention.
  • 3C schematically illustrates a chest belt connected to an EIT data processing apparatus according to an embodiment of the present invention.
  • FIG. 3D schematically illustrates a neck belt connected to an EIT data processing apparatus according to an embodiment of the present invention.
  • FIG. 4 is a flowchart illustrating a method of operating a non-invasive mechanical ventilation system in accordance with an embodiment of the present invention.
  • FIG. 5 is a flowchart illustrating an operation method of an EIT data processing apparatus according to an embodiment of the present invention.
  • FIG. 6 is a flow diagram illustrating a method of operating a non-invasive mechanical ventilation system in accordance with an embodiment of the present invention.
  • FIG. 7 is a diagram illustrating components related to a cloud computing service of an EIT data processing apparatus according to an embodiment of the present invention. Referring to FIG.
  • first component is "(functionally or communicatively) connected” or “connected” to another (second) component, May be connected directly to the component, or may be connected through another component (e.g., a third component).
  • the term “configured to” is intended to encompass all types of information, including, but not limited to, “ , “” Made to “,” can do “, or” designed to ".
  • the expression "a device configured to” may mean that the device can “do " with other devices or components.
  • a processor configured (or configured) to perform the phrases "A, B, and C" may be implemented by executing one or more software programs stored in a memory device or a dedicated processor (e.g., an embedded processor) , And a general purpose processor (e.g., a CPU or an application processor) capable of performing the corresponding operations.
  • a dedicated processor e.g., an embedded processor
  • a general purpose processor e.g., a CPU or an application processor
  • FIG. 1 is a view for explaining an embodiment of a non-invasive mechanical ventilation system according to an embodiment of the present invention.
  • Figure 1 illustrates a non-invasive mechanical ventilation system in accordance with one embodiment of the present invention for treating respiratory and neurological diseases of a subject in a non-invasive manner.
  • the non-invasive mechanical ventilation system 100 includes an electrical impedance tomography (EIT) data processing unit 110, a breathing management unit 120, and a control unit 130.
  • EIT electrical impedance tomography
  • the non-invasive mechanical ventilation system 100 collects impedance data through the thoracic electrode part 111 and the neck electrode part 112.
  • the non-invasive mechanical ventilation system 100 injects air or collects respiratory parameters through the tube 121 connected to the mask.
  • a plurality of electrodes of the chest electrode unit 111 may be formed on the base plate at regular intervals.
  • the base plate may have a certain length and width so as to measure the impedance in a state of being wrapped around the subject to be measured including the chest or abdomen of the subject, but the length and width may be varied according to the embodiment, It is not limited to the chest electrode unit 111.
  • the chest electrode unit 111 may be attached to the subject's chest to effectively measure the electric field distribution on the surface near the chest by changing the electrode array structure and the measurement structure by arranging a plurality of electrodes two-dimensionally or three-dimensionally can do.
  • the chest electrode unit 111 may include a plurality of electrodes for current injection and voltage sensing.
  • the chest electrode unit 111 can supply a current to at least one selected electrode pair of the plurality of electrodes, and measure the voltage through the unselected electrodes.
  • a plurality of electrodes included in the chest electrode unit 111 are attached at appropriate intervals to appropriate positions of the chest, such as between the ribs 5-6, and the chest electrode unit 111 injects an alternating current And the induced voltage is measured using the remaining electrodes.
  • the EIT data processing unit 110 may image the impedance data obtained through the chest electrode unit 111 to quantify the lung internal air distribution and volume.
  • the EIT data processing unit 110 may generate image data related to the air distribution and the volume of the lungs located inside the chest based on the voltage measured through the chest electrode unit 111.
  • a plurality of electrodes of the neck electrode unit 112 may be formed on the base plate at regular intervals.
  • the base plate may have a certain length and width so as to measure the impedance in a state of being wrapped around the subject's neck.
  • the length and width of the base plate may be varied according to the embodiment, It does not.
  • the neck electrode portion 112 is attached to the subject's neck to effectively measure the electric field distribution on the surface near the chest by changing the electrode array structure and the measurement structure by arranging the plurality of electrodes two-dimensionally or three-dimensionally can do.
  • the neck electrode portion 112 may include a plurality of electrodes for current injection and voltage sensing.
  • the neck electrode portion 112 can supply a current to at least one of the plurality of selected electrode pairs, and measure the voltage through the unselected electrodes.
  • the EIT data processing unit 110 may image the impedance data obtained through the chest electrode unit 111 to quantify the lung internal air distribution and volume.
  • the EIT data processing unit 110 may image the impedance data obtained through the neck electrode unit 112 to quantify the degree of closure of the upper airway.
  • the EIT data processing unit 110 measures the impedance using the chest electrode unit 111 or the neck electrode unit 112, and generates image data for lung or airway using the measured impedance can do.
  • the EIT data processing unit 110 repeatedly performs such measurement while injecting a current between several electrodes.
  • the measured electrical voltage data induced by a plurality of injected currents can be used to reconstruct the electrical conductivity changes of the thoracic section.
  • the EIT data processing unit 110 can perform image restoration at a rate of 25 frames per second.
  • the conductivity value of lung tissue may be inversely proportional to the volume of air in the alveoli within the tissue.
  • this signal can indicate that the lung internal air volume has changed with time.
  • the respiration management unit 120 can provide accurate inhalation, exhalation pressure, or one-time breathing depending on the degree of function of the subject.
  • the respiratory management unit 120 can inject air into the subject through the mask and the tube connected to the mask, while changing the amount of air to be injected according to the degree of function of the subject.
  • the respiration management unit 120 may sense the air pressure and the airflow signal inside the mask.
  • the respiratory management unit 120 includes an air pump, and can control an air pump to control the pressure and volume of air to be injected.
  • the respiratory management unit 120 may inject air and collect respiratory parameters of the subject upon air injection.
  • control unit 130 may control the EIT data processing unit 110 and the respiration management unit 120.
  • control unit 130 may measure the subject's lung air distribution and volume change based on the impedance data obtained by controlling the EIT data processing unit 110.
  • the control unit 130 may control the air injection amount based on the respiration parameters collected through the respiration management unit 120 and the lung internal air distribution measured through the EIT data processing unit 110, have.
  • the control unit 130 when the controller 130 maintains one of the volume and the pressure of the air injected through the mask, the control unit 130 outputs an output value corresponding to one of the volume and the pressure held by the respiration management unit 120, Value, and to control the injected air to be maintained according to the determined output power value.
  • the present invention can determine the output proper value as the output of the respiratory management unit 120 and continuously supply the air corresponding to the determined output.
  • control unit 130 controls the respiration management unit 120 so that the air injected with the determined output power value is maintained.
  • the state change of the subject is detected through the EIT data processing unit, And controls the air injected through the mask.
  • control unit 130 may be configured to generally maintain the output of the air injected through the respiratory management unit 120, and to automatically control the air output when necessary.
  • the present invention can increase the efficiency of non-invasive mechanical ventilation therapy by using a combination of existing non-invasive treatment methods and electrical impedance tomography (EIT) methods.
  • EIT electrical impedance tomography
  • the non-invasive mechanical ventilation system 100 may perform signal processing associated with the collection of impedance data and respiratory parameters simultaneously with non-invasive mechanical ventilation therapy.
  • the non-invasive mechanical ventilation system 100 simultaneously implements imaging of impedance data and collection of respiratory parameters while improving the lung function of the subject in a non-invasive manner or treating the myopathy.
  • the imaging of the impedance data may be included in the process of generating the image data.
  • FIG. 2 is a diagram illustrating components of a non-invasive mechanical ventilation system according to an embodiment of the present invention.
  • the non-invasive mechanical ventilation system 200 includes an EIT data processing device 210, a respiration management unit 220, and a control unit 230.
  • the EIT data processing apparatus 210 is attached to at least one of the chest and neck of a subject to be measured, and includes a plurality of electrodes for current injection and voltage sensing.
  • the EIT data processing device 210 supplies current to at least one selected electrode pair of the plurality of electrodes, and measures the voltage through the unselected electrodes.
  • the EIT data processing apparatus 210 generates image data for at least one of the chest and the neck from the impedance data generated based on the measured voltage.
  • a plurality of electrodes may be attached along the subject's chest to include an EIT electrode for measuring impedance data for the interior of the lungs.
  • the plurality of electrodes may include an EIT electrode attached along the subject's neck to measure impedance data for the area of the upper figure.
  • the EIT data processing apparatus 210 can process the impedance data to generate image data.
  • the EIT electrode is used to measure the induced voltage by injecting a relatively low current, for example 1 mA or less, which can not be sensed by the subject.
  • the current-voltage data measured through the EIT electrode is transmitted to the chest ) Can be used to detect structural changes that cause closure and its closure.
  • the current-voltage data measured through the EIT electrode can be used to detect structural changes inside the neck via an imaging algorithm.
  • the EIT data processing device 210 controls the selection of at least one or more electrode pairs at a plurality of electrodes, controls the selection of unselected electrodes, And generates image data for at least one of the internal changes.
  • the EIT data processing apparatus 210 images the lungs and the airways that are located inside the thorax and the neck, which are changed according to the air to be injected.
  • the EIT data processing apparatus 210 can inject a current having a plurality of frequency ranges through at least one selected electrode pair among a plurality of electrodes attached to the subject's chest.
  • the EIT data processor 210 selects a selected electrode pair and frequency, generates a voltage signal according to the selected frequency and converts it into a current, and injects the converted current into the subject's chest or neck through selected electrode pairs can do.
  • the EIT data processing apparatus 210 can measure an induced voltage according to a current injected from unselected electrodes among a plurality of electrodes.
  • the EIT data processing apparatus 210 removes the noise contained in the detected voltage based on the slope of the measured voltage, and when the slope of the detected voltage exceeds the predetermined threshold value, The voltage of the excess section can be replaced with the predetermined voltage value.
  • the respiration management unit 220 may inject air into the subject and collect respiratory parameters of the subject based on the air to be injected.
  • the respiratory management unit 220 includes a mask that is in contact with one of the subject's nose and mouth and a tube that is connected to the mouth opposite to the mask, and injects air into the subject through the mask, Air pressure and respiratory parameters associated with the airflow signal.
  • the breathing parameters are sampled at about the same time as or simultaneously with the reading of the impedance image.
  • the breathing parameters include a shape of the subject's breathing curve, a change in the shape of the subject's breathing curve, a breathing curve based on the subject's breathing amount, a breathing curve based on the breathing amount of the subject, , A breathing curve based on the subject's exhalation pressure, a breathing curve based on the subject's inspiratory flow, a breathing curve based on the subject's breathing air, and a change in subject's respiratory interval, and combinations thereof have.
  • the respiratory parameters may be related to the subject's respiratory rate, the subject's respiratory pressure, the subject's respiratory airflow, the subject's end-tidal CO 2 , the subject's sublingual CO 2 , and the subject's respiratory intensity.
  • the respiratory management unit 220 may include an external device connection unit 221 to which at least one of an air purifier, a replaceable water bottle, and a replaceable oxygen can is connected.
  • the respiratory administration unit 220 can provide the air purified by the air cleaner to the subject through the external device connection unit 221 or adjust the humidity of the air supplied to the subject by spraying the water supplied from the replaceable water bottle have.
  • the respiratory administration unit 220 can supply the subject with oxygen supplied from the replaceable oxygen cans through the external device connection unit 221.
  • the respiratory administration unit 220 can provide a specific substance contained in the water of the replaceable water bottle to the subject through the external device connection unit 221.
  • a specific substance may include water-soluble vitamins capable of dissolving in water, water-soluble vaccines, water-soluble therapeutic agents, and the like.
  • the respiratory administration unit 220 can control the humidity of the air supplied to the subject while spraying water to the subject, and at the same time, provide the subject with a specific substance.
  • the external device connection portion 221 may include a cable for the air purifier, a replaceable oxygen can, and a converter-type connection into which a replaceable water bottle can be inserted.
  • the present invention can provide medical care for health care to not only patients having respiratory diseases but also normal people by providing purified air of the air purifier and purified oxygen contained in the oxygen can as subjects.
  • control unit 230 may control the EIT data processing apparatus 210 and the respiration management unit 220.
  • the controller 230 may compare the respiratory parameter and the image data to estimate the amount of air to be injected.
  • the present invention can accurately estimate the amount of air leaked from the inside of the mask by using the electrical impedance tomography method in non-invasive mechanical ventilation treatment.
  • control unit 230 can control the pressure and the volume of the air to be injected based on the estimated leakage amount.
  • control unit 230 can calculate the airflow signal inside the lung by differentiating the monitored change in the volume of air inside the lung, and estimate the leakage amount of the air to be injected in comparison with the airflow signal measured in the mask.
  • the control unit 230 when the estimated leakage amount is larger than the reference value, the control unit 230 increases one of the volume and the pressure of the air injected through the mask. If the estimated leakage amount is smaller than the reference value, It is possible to maintain one of the volume and the pressure of the air to be injected.
  • the reference value may correspond to a reference value for indicating normalization of pulmonary function of the air injected through the mask.
  • the control unit 230 determines that air corresponding to the reference value for indicating the normalization of the lung function is not injected. If the leakage amount is smaller than the reference value, It is determined that the corresponding air is injected.
  • the present invention can actively control the pressure and volume of air injected in non-invasive mechanical ventilation treatment by accurately estimating the amount of air leaked.
  • the reference value may be associated with image data about the volume of the lung that varies with the injection air.
  • the controller 230 may calculate the lung function diagnosis parameter using the generated image data and the collected respiration parameters.
  • control unit 230 arbitrarily changes the pressure and volume of the air injected by the respiratory management unit 220.
  • controller 230 controls the EIT data processing apparatus to image changes in air distribution, volume, and airflow inside the lungs of the chest according to the changed pressure and volume, and generates image data on the change in the area of the neck .
  • control unit 230 acquires a change in respiratory parameters collected by the respiration management unit 220.
  • the change in the respiratory parameter may be based on the air to be injected depending on the changed pressure and volume.
  • controller 230 may calculate the pulmonary function diagnostic parameters using the imaged air distribution, changes in volume and airflow, and changes in the respiratory parameters.
  • control unit 230 controls the respiration management unit 220 to monitor changes in the subject's lungs and upper airway through the EIT data processing device 210 and the respiration management unit 220 while changing the pressure and volume of air to be injected.
  • the lung function diagnosis parameter can be calculated.
  • the pulmonary function diagnostic variable may include at least one of a gain of a non-invasive mechanical ventilation system, a subject's arousal threshold, and the degree of responsiveness.
  • the present invention can calculate the subject's diagnostic parameters using the breathing parameters of the subject collected through the mask and the monitoring of lung function based on electrical impedance tomography.
  • the present invention can accurately estimate the amount of air leaking from the mask in performing the non-invasive treatment method, thereby improving the therapeutic effect of respiratory diseases or muscular system diseases.
  • the present invention also provides a non-invasive treatment method that accurately estimates the amount of air leaked from a mask attached to a subject and controls one of the volume and pressure of air injected through the mask based on the estimated amount of air, Lung function can be improved.
  • the non-invasive mechanical ventilation system 200 connects non-invasive mechanical ventilation to a mask worn by a subject and induces a natural sleep of the subject.
  • the non-invasive mechanical ventilation includes a respiration management unit.
  • the non-invasive mechanical ventilation system 200 sets the output air pressure or volume of the respiratory management unit 220 to a minimum value at the beginning of sleep.
  • the non-invasive mechanical ventilation system 200 uses the EIT data processing device 210 to measure the pulsation internal air volume change signal and to generate the non-invasive mechanical ventilation signal.
  • the non-invasive mechanical ventilation system 200 measures the air pressure and the airflow signal of the mask through the respiration management unit 220.
  • the non-invasive mechanical ventilation system 200 compares the internal air volume change signal of the lung with the mask air pressure and the airflow signal to estimate the amount of air leaking from the mask.
  • the non-invasive mechanical ventilation system 200 detects the occurrence of apnea or hypopnea using the lung internal air volume change signal.
  • the non-invasive mechanical ventilation system 200 continuously estimates the amount of air leaking from the mask while increasing the output air pressure or volume of the respiratory management unit 220 when apnea or low respiration occurs.
  • a minimum value of the output air pressure or volume of the respiration management unit 220 in which apnea or hypopnea does not occur is determined by determining whether the frequency of apnea or hypopnea is reduced according to the increase of the output air pressure or volume of the respiration management unit 220.
  • the procedure described above may be a PAP titration procedure for improving pulmonary function.
  • the non-invasive mechanical ventilation system 200 may set the minimum value of the output air pressure or volume of the respiration management unit 220 found by the air adequacy estimation procedure as the default value of the respiration management unit 220 operating in the CPAP mode.
  • the non-invasive mechanical ventilation system 200 maintains a default setting when the patient adapts to the CPAP method when the respiratory management unit 220 is used without measurement of the impedance data.
  • the respiration managing unit 220 When the respiration managing unit 220 is used without measuring the impedance data, if the patient does not adapt to the CPAP method again, the air adequacy estimating process using the respiration managing unit 220 and the EIT data processing unit 210 is repeated.
  • the output air of the respiratory management unit 220 The minimum value of the pressure or volume is compared with the value obtained in the previous air titration procedure result.
  • the non-invasive mechanical ventilation system 200 uses a new value as a default setting value when the value is changed.
  • the non-invasive mechanical ventilation system 200 always performs the measurement using the EIT data processing apparatus during the use of the respiration management unit 220,
  • the output air pressure or volume of the management unit 220 can be continuously and real-time controlled.
  • 3A is a view for explaining components of an EIT data processing apparatus according to an embodiment of the present invention.
  • Fig. 3A relates to an embodiment in which the EIT data processing apparatus is constituted by a device separate from the respiration management apparatus and controls the air injection of the respiration management apparatus.
  • the EIT data processing apparatus 300 includes an electrode unit 301, an image data generation unit 302, an air leakage amount estimation unit 304, a control signal generation unit 305, and a signal transmission unit 303, .
  • the EIT data processing apparatus 300 may be directly connected to the respiration management apparatus 310 through a serial cable, or may be connected through short-range wireless communication such as Bluetooth or Wi-Fi.
  • the EIT data processing apparatus 300 may be a separate apparatus separate from the respiration management apparatus 310.
  • the electrode unit 301 is formed with a plurality of electrodes for current injection and voltage sensing, and may be attached to at least one part of the subject's chest and neck to be measured.
  • the electrode unit 301 may include the thoracic electrode unit and the neck electrode unit described in FIG.
  • the image data generation unit 302 may supply current to at least one selected electrode pair among a plurality of electrodes.
  • the image data generation unit 302 may measure voltage through unselected electrodes to generate image data for at least one of the chest and the neck from the impedance data.
  • the image data generation unit 302 controls selection of at least one electrode pair in a plurality of electrodes, controls selection of unselected electrodes, Based on at least one of the air-based chest and neck.
  • the signal transmitting unit 303 may transmit the signal data extracted from the image data and the image data to the respiration management apparatus 310.
  • the signal data may include at least one of voltage signal data, current signal data, impedance signal data, and frequency signal data.
  • the signal transmitter 303 may transmit a control signal to the respiration management device 310.
  • the signal transmitter 303 may transmit a control signal for controlling one of the volume and the pressure of air to the respiration management device 310 using wire / wireless communication.
  • the air leakage estimating unit 304 receives the respiration parameter according to the respiration of the subject, compares the received respiration parameter and the generated image data, and estimates the amount of air leaking into the subject have.
  • the air leakage estimating unit 304 may monitor any one of a change in lung internal air volume and a change in the degree of closing of the airway based on the image data.
  • the air leakage amount estimating unit 304 calculates the airflow signal by differentiating the monitored change in the air volume in the lung and compares the airflow signal in the mask included in the respiration management apparatus 310 with the calculated airflow signal to calculate the air leakage amount Can be estimated.
  • the control signal generating unit 305 may generate a control signal for controlling the pressure and volume of the air injected by the respiratory management apparatus 310 based on the estimated leakage amount.
  • control signal generating unit 305 may generate a control signal for controlling the pressure and volume of air injected by the respiratory management apparatus 310 to improve the lung function of the subject.
  • the present invention can monitor the lung function based on electrical impedance tomography and generate a control signal for controlling the respiration management apparatus based on the monitoring.
  • the control signal generation unit 305 controls the respiration management apparatus 310 to increase one of the volume and the pressure of air injected through the mask Can be generated.
  • the control signal generator 305 may generate a control signal for controlling the respiration management apparatus 310 to maintain one of the volume and the pressure of the air injected through the mask when the estimated leakage amount is smaller than the reference value have.
  • FIG. 3B is a diagram illustrating a connection configuration between an EIT data processing apparatus and a respiration management apparatus according to an embodiment of the present invention.
  • the EIT data processing device 320 can be connected to the respiration management device 330 using a cable.
  • the EIT data processing apparatus 320 may include the same components as the EIT data processing apparatus 310 shown in FIG. 3A.
  • the EIT data processing device 320 generates a control signal and transmits the control signal to the respiration management device 330 to control the air injection of the respiration management device 330.
  • the EIT data processor 320 may obtain the impedance data through the chest electrode unit attached to the subject to generate image data for lungs located in the inside of the chest have.
  • the EIT data processing unit 320 may obtain the impedance data through the neck electrode unit, and generate image data for the position located inside the neck.
  • the EIT data processing apparatus 320 acquires impedance data through an electrode branched from a cable connected to a mask of the respiration management apparatus 330, Can be generated.
  • the EIT data processing apparatus 320 may generate image data on the lung and the upper limb by using the impedance data measured by the respiration management apparatus 330.
  • 3C schematically illustrates a chest belt connected to an EIT data processing apparatus according to an embodiment of the present invention.
  • the chest belt 350 may be connected to the EIT data processing unit 320 shown in FIG. 3B.
  • the chest belt 350 includes an electric cable 351, a laser cable 352 and an electrode belt 353.
  • the electrode belt 353 may correspond to the chest electrode unit 111 shown in Fig.
  • FIG. 3D schematically illustrates a neck belt connected to an EIT data processing apparatus according to an embodiment of the present invention.
  • the neckband 360 may be connected to the EIT data processing apparatus 320 shown in FIG. 3B.
  • the neck strap 360 can transmit and receive electricity and data through a cable.
  • the neckband 360 may correspond to the neck electrode unit 112 shown in Fig.
  • FIG. 4 is a flowchart illustrating a method of operating a non-invasive mechanical ventilation system in accordance with an embodiment of the present invention.
  • FIG. 4 illustrates a non-invasive mechanical ventilation system of a subject in a method of operating a non-invasive mechanical ventilation system.
  • step 401 a method of operation of a non-invasive mechanical ventilation system injects air into a subject.
  • the non-invasive mechanical ventilation system operates by injecting air into the subject through the mask of the respiratory management unit.
  • the method of operating the non-invasive mechanical ventilation system in step 402 comprises the steps of measuring the voltage from at least one site through a plurality of electrodes attached to at least one of the chest and neck of the subject, do.
  • a method of operating a non-invasive mechanical ventilation system includes measuring a voltage associated with at least one of the chest and neck using a plurality of electrodes and generating image data for one of the chest and neck.
  • the non-invasive mechanical ventilation system can selectively image the chest and neck.
  • step 403 the method of operation of the non-invasive mechanical ventilation system collects respiratory parameters of the subject.
  • the method of operation of a non-invasive mechanical ventilation system collects breathing parameters that are altered based on breathing with air being injected into the subject through the mask.
  • the respiratory parameter may include the air pressure inside the mask and the airflow signal. That is, the respiratory parameter may be related to the air pressure and the airflow signal inside the mask when the subject breathed.
  • the method of operating the non-invasive mechanical ventilation system in step 404 estimates the amount of air leakage by comparing the generated image data and the collected respiratory parameters.
  • the non-invasive mechanical ventilation system operates by calculating the airflow signal by differentiating the lung internal air volume change monitored based on the impedance data, and estimating the amount of air leaked from the mask by comparing with the airflow signal in the mask.
  • the method of operation of the non-invasive mechanical ventilation system in step 405 controls the air to be injected based on the estimated leakage amount.
  • the non-invasive mechanical ventilation system operation method improves the efficiency of the non-invasive mechanical ventilation treatment by controlling one of the volume and pressure of the air to be injected according to the amount of air leaking from the mask.
  • the operation method of the non-invasive mechanical ventilation system determines that the amount of air leaking from the mask is larger than the reference value, the pressure and volume of the air are increased so that sufficient air is injected into the subject to improve the lung function. .
  • FIG. 5 is a flowchart illustrating an operation method of an EIT data processing apparatus according to an embodiment of the present invention.
  • FIG. 5 illustrates an example of generating a control signal for controlling the pressure and volume of air injected into a subject based on measurement of impedance data to improve the lung function of the subject, do.
  • an operation method of the EIT data processing apparatus will be described with reference to an apparatus operation method.
  • a method of operating a device supplies current to selected pairs of electrodes among a plurality of electrodes attached to one of the chest and neck.
  • the apparatus operation method supplies electric current to at least one selected electrode pair among a plurality of electrodes attached to at least one part of the chest and neck of a subject to be measured.
  • a method of operating a device measures the voltage across unselected electrodes of a plurality of electrodes to image the interior of one of the chest and neck.
  • a device operation method measures voltage through unselected electrodes of a plurality of electrodes to image the interior of at least one of the thorax and the neck from the impedance data.
  • the apparatus operation method may transmit the signal data extracted from the image data and the image data generated in step 502 to the respiration management apparatus.
  • step 503 the device operating method receives the breathing parameters and estimates the amount of air leakage based on the received breathing parameters and the imaged interior.
  • the device operation method can receive the subject's respiratory parameters and estimate the amount of air leaked into the subject based on the received breath parameters and the imaged interior.
  • step 504 the device operating method generates a control signal for controlling the pressure and volume of air injected by the respiratory management device.
  • the apparatus operation method generates a control signal for controlling the pressure and volume of air injected by the respiratory management apparatus based on the estimated leakage amount.
  • control signal may be generated to improve the lung function of the subject.
  • step 505 the device operation method transfers the control signal generated in step 504 to the respiration management device.
  • FIG. 6 is a flow diagram illustrating a method of operating a non-invasive mechanical ventilation system in accordance with an embodiment of the present invention.
  • FIG. 6 illustrates an embodiment in which a non-invasive mechanical ventilation system operates to calculate lung function diagnostic parameters based on respiratory parameters and image data generated by an EIT data processor.
  • FIG. 6 illustrates a method of operating a non-invasive mechanical ventilation system in a system operating method.
  • step 601 the method of operating the system injects air into the subject.
  • the system operation method injects air into the subject through the mask of the respiration management unit.
  • a system operation method supplies a current to a selected one of a plurality of electrodes, and measures a voltage with an unselected electrode to generate image data of the inside of the subject.
  • the impedance related to the inside of one of the chest and the neck is measured using a plurality of electrodes, and the image data of the inside of one of the chest and the neck is generated using the impedance data.
  • step 603 the method of operating the system collects respiratory parameters of the subject.
  • the subject breathes using the air injected into the subject through the mask, and collects respiratory parameters that are changed based on the breath.
  • the respiratory parameter may include the air pressure inside the mask and the airflow signal.
  • step 604 the system operation method calculates lung function diagnostic parameters using image data and respiratory parameters.
  • the system operating method calculates the pulmonary function diagnostic parameters based on the lungs internal air distribution, volume and airflow changes, and throat area change.
  • the pulmonary function diagnosis variable includes at least one of the respiratory system gain or sensitivity of the subject, the subject's respiratory insufficiency arousal threshold and the degree of responsiveness.
  • the system operation method can diagnose the severity and cause of sleep apnea using the lung function diagnosis parameters.
  • the system operating method changes the air pressure applied to the airway. Thereafter, the system operation method uses the EIT data processing unit to measure the change in the area of the area by the impedance tomography near the neck, and calculate the above-mentioned degree of response to discriminate the severity and cause of the sleep apnea.
  • the system operation method is a respiration management unit that measures air distribution and volume of the lungs by impedance tomography at the chest while varying the air pressure applied to the airway.
  • the system operation method can determine the severity and cause of sleep apnea by measuring the area of the upper limb by impedance tomography near the neck to calculate the gain, arousal threshold and the response of the respiratory control system.
  • the system operation method can diagnose the severity and cause of sleep apnea, and establish a sleep apnea treatment plan that defines sleep apnea treatment methods.
  • FIG. 7 is a diagram illustrating components related to a cloud computing service of an EIT data processing apparatus according to an embodiment of the present invention. Referring to FIG.
  • FIG. 7 illustrates an embodiment in which the EIT data processing apparatus provides the subject's biometric data to at least one of a plurality of Internet of things (IoT) and a user terminal using the cloud computing service .
  • IoT Internet of things
  • the EIT data processing apparatus 710 is connected to the respiration management apparatus 700 via wire / wireless.
  • the EIT data processing apparatus 710 may generate and transmit a control signal for controlling the air injection of the respiration management apparatus 700.
  • the EIT data processing apparatus 710 transmits and receives data to and from at least one of a plurality of object Internet apparatuses and a user terminal apparatus via a network.
  • the EIT data processing apparatus 710 includes a signal transfer unit (not shown).
  • the signal transmitting unit (not shown) transmits the biometric data of the subject based on one of the image data and the signal data to at least one of the plurality of object Internet apparatuses and the user terminal apparatus using the cloud computing service.
  • the EIT data processor 710 may generate at least one of the lungs and the above-mentioned image data that changes in real time through a plurality of electrodes attached to at least one of the chest and neck of the subject.
  • the subject's biometric data may include electrocardiography, heartbeat, arrhythmia, lung ventilation imaging, tidal volume, apnea, May include at least one of a hypopnea, a body position, a movement, a snoring sound, a body composition, and a personal health state. have.
  • the EIT data processing apparatus 710 can output the two-dimensional image of the lung or the upper diagram using the first object Internet apparatus 720 using the cloud computing service.
  • the EIT data processing device 710 may display a closed or top-view image using the second-object Internet device 721 using the cloud computing service.
  • the EIT data processing apparatus 710 can detect a change in the subject's personal health status and change the shooting direction of the third-party Internet device 722 using the cloud computing service according to the change.
  • the EIT data processing device 710 can detect a change in the subject's personal health status and change the operational status of the fourth-party Internet device 723 using the cloud computing service.
  • the EIT data processing apparatus 710 may transmit the subject's biometric data to the user terminal 724 and recommend an application related to the biometric data using the cloud computing service.
  • the EIT data processing apparatus 710 may provide the web service based on the subject's biometric data to the user terminal 724 using the cloud computing service.
  • the EIT data processing device 710 can share biometric data of a subject with a smart watch, a band, a balance, etc., which are components of the home IOT platform.
  • the method according to an embodiment may be implemented in the form of a program command that can be executed through various computer means and recorded in a computer-readable medium.
  • the computer-readable medium may include program instructions, data files, data structures, and the like, alone or in combination.
  • the program instructions to be recorded on the medium may be those specially designed and configured for the embodiments or may be available to those skilled in the art of computer software.
  • Examples of computer-readable media include magnetic media such as hard disks, floppy disks and magnetic tape; optical media such as CD-ROMs and DVDs; magnetic media such as floppy disks; Magneto-optical media, and hardware devices specifically configured to store and execute program instructions such as ROM, RAM, flash memory, and the like.
  • program instructions include machine language code such as those produced by a compiler, as well as high-level language code that can be executed by a computer using an interpreter or the like.
  • the hardware devices described above may be configured to operate as one or more software modules to perform the operations of the embodiments, and vice versa.

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Abstract

La présente invention concerne un système de ventilation mécanique non invasif pour mesurer le volume d'air dans un poumon et le degré d'obstruction des voies respiratoires ainsi que son procédé de fonctionnement. Un système de ventilation mécanique non invasif selon un mode de réalisation de la présente invention peut comprendre : une unité de traitement de données EIT comprenant une pluralité d'électrodes fixées à au moins une partie de la poitrine et au cou d'un sujet et générant des données d'image de l'intérieur du sujet en mesurant une tension de l'au moins une partie par le biais de la pluralité d'électrodes fixées ; une unité de gestion de respiration pour injecter de l'air dans le sujet et collecter des paramètres respiratoires du sujet sur la base de l'air à injecter ; et une unité de commande pour comparer les paramètres de respiration collectés et les données d'image générées, et pour commander l'air injecté en estimant une quantité de fuite de l'air injecté.
PCT/KR2018/013718 2018-01-29 2018-11-12 Système de ventilation mécanique non invasif pour mesurer des changements de volume d'air dans un poumon et le degré d'obstruction des voies respiratoires et son procédé de fonctionnement WO2019146888A1 (fr)

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