WO2019137372A1 - 一种放射治疗设备及系统 - Google Patents

一种放射治疗设备及系统 Download PDF

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Publication number
WO2019137372A1
WO2019137372A1 PCT/CN2019/070849 CN2019070849W WO2019137372A1 WO 2019137372 A1 WO2019137372 A1 WO 2019137372A1 CN 2019070849 W CN2019070849 W CN 2019070849W WO 2019137372 A1 WO2019137372 A1 WO 2019137372A1
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Prior art keywords
treatment head
treatment
radiation therapy
head
knife
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PCT/CN2019/070849
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English (en)
French (fr)
Inventor
赵洪斌
刘海峰
钟铭
王慧亮
Original Assignee
西安大医集团有限公司
深圳市奥沃医学新技术发展有限公司
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Publication of WO2019137372A1 publication Critical patent/WO2019137372A1/zh
Priority to US16/927,334 priority Critical patent/US11504553B2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1084—Beam delivery systems for delivering multiple intersecting beams at the same time, e.g. gamma knives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1081—Rotating beam systems with a specific mechanical construction, e.g. gantries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/04—Positioning of patients; Tiltable beds or the like
    • A61B6/0407—Supports, e.g. tables or beds, for the body or parts of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065—Beam adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1095—Elements inserted into the radiation path within the system, e.g. filters or wedges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/01—Devices for producing movement of radiation source during therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
    • A61N5/1045—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT

Definitions

  • the present disclosure relates to the field of medical device technology, and in particular, to a radiation therapy device and system.
  • Radiation therapy has become one of the main means of treating malignant tumors.
  • mainstream radiation therapy equipment includes gamma ray radiotherapy equipment and X-ray radiotherapy equipment.
  • the doctor In the actual radiotherapy process, regardless of the radiotherapy equipment used, the doctor usually hopes that the dose rate of the tumor target area is as large as possible, and the larger the dose rate of the tumor target area, the more the DNA strand of the tumor cell can be destroyed, and the better the therapeutic effect.
  • the dose rate refers to the dose received per unit time in the tumor target area.
  • Embodiments of the present disclosure provide a radiotherapy apparatus comprising: a first treatment head; a second treatment head, the second treatment head intersecting a beam of the first treatment hair at an intersection; wherein the One treatment head is an X-knife treatment head, and the second treatment head is an X-knife treatment head, a multi-source focusing treatment head or a conformal intensity-modulating treatment head.
  • the X-knife treatment head includes: a channel collimator for limiting a beam; wherein the channel collimator comprises: a plurality of beam channels, any two of the shots At least one of the aperture and shape of the beam channel is different; or the channel collimator comprises a single beam channel, the shape and/or size of the single beam channel being adjustable.
  • the X-knife treatment head further includes an accelerator for emitting the beam.
  • the X-knife treatment head further includes: a multi-leaf collimator for conforming the beam, the multi-leaf collimator being coupled to the channel collimator; wherein The channel collimator is used to limit the beam after the multi-leaf collimator is conformed.
  • the channel collimator is detachably coupled to the multi-leaf collimator.
  • the channel collimator is movable relative to the multi-leaf collimator.
  • the first treatment head and/or the second treatment head are disposed on a rotating gantry.
  • the first treatment head and/or the second treatment head are reciprocally rotatable or 360° continuously rotated about a rotational axis of the rotating gantry.
  • the first treatment head and/or the second treatment head are movable or oscillated in the axial direction of the rotational axis of the rotating gantry.
  • a radial angle between a beam centerline of the first treatment head and a center line of the second treatment head beam is less than or equal to 180°; wherein the radial angle is: An angle between an orthographic projection of a beam centerline of the first treatment head at a first section and an orthographic projection of a beam centerline of the second treatment head at the first section, the first section being vertical A section of the rotating shaft.
  • an axial angle between a beam centerline of the first treatment head and a beam centerline of the second treatment head is less than or equal to 90°; wherein the axial angle is : an angle between an orthographic projection of the beam centerline of the first treatment head at a second section and an orthographic projection of a beam centerline of the second treatment head at the second section, the second section being A section parallel to or through the axis of rotation.
  • the radiation therapy apparatus further includes: a third treatment head, the beam of the third treatment hair intersecting the beam of the first treatment head and the second treatment hair The intersection point; wherein the third treatment head is an X-knife treatment head, a multi-source focusing treatment head or a conformal intensity-modulating treatment head.
  • the second treatment head is an X-knife treatment head and the third treatment head is an X-knife treatment head.
  • the first treatment head and/or the second treatment head and/or the third treatment head are disposed on a rotating gantry.
  • the first treatment head and/or the second treatment head and/or the third treatment head are movable or oscillating in the axial direction of the rotational axis of the rotating gantry.
  • the first treatment head, the second treatment head, and the third treatment head are disposed on a fixture that is coupled to the rotating gantry.
  • the radial angle between two adjacent treatment heads is between 5° and 45°; the radial angle is: the beam centerline of two adjacent treatment heads is first An angle of an orthographic projection of a section, the first section being a section perpendicular to the axis of rotation.
  • the rotating gantry is a drum frame or a C-arm.
  • the multi-source focus treatment treats an X-ray or gamma beam that treats the hair as an X-ray or gamma beam.
  • Embodiments of the present disclosure provide a radiation therapy system comprising: a treatment bed, and a radiation therapy device as described above.
  • FIG. 1 is a schematic structural diagram of a radiotherapy apparatus according to an embodiment of the present disclosure
  • FIG. 2 is a schematic structural view of an X-knife treatment head according to an embodiment of the present disclosure
  • FIG. 3 is a schematic structural diagram of a channel collimator according to an embodiment of the present disclosure.
  • FIG. 4 is a schematic structural diagram of another channel collimator according to an embodiment of the present disclosure.
  • FIG. 5 is a schematic structural diagram of still another channel collimator according to an embodiment of the present disclosure.
  • FIG. 6 is a schematic structural view of a radiation therapy apparatus when the second treatment head is an X-knife treatment head in the embodiment of the present disclosure
  • FIG. 7 is a schematic structural view of a radiation therapy apparatus when the second treatment head is a multi-source focusing treatment head in the embodiment of the present disclosure
  • FIG. 8 is a schematic structural view of a radiation therapy apparatus when the second treatment head is a conformal intensity-modulating treatment head according to an embodiment of the present disclosure
  • FIG. 9 is a schematic view showing an axial angle between a first treatment head and a second treatment head beam center line in the embodiment of the present disclosure.
  • FIG. 10 is a radiation therapy apparatus including a third treatment head according to an embodiment of the present disclosure.
  • FIG. 11 is a schematic structural view of a radiation therapy apparatus when the second treatment head and the third treatment head are X-knife treatment heads in the embodiment of the present disclosure;
  • FIG. 12 is a schematic structural view of a radiation therapy apparatus when a first treatment head, a second treatment head, and a third treatment head are disposed in a fixing device in an embodiment of the present disclosure
  • FIG. 13 is a schematic view showing the structure of a radiotherapy apparatus when the first treatment head is an X-knife treatment head, the second treatment head is a multi-source focusing treatment head, the third treatment head, and the fourth treatment head is an X-knife treatment head in the embodiment of the present disclosure. .
  • FIG. 1 is a schematic structural diagram of a radiotherapy apparatus according to an embodiment of the present disclosure.
  • the radiotherapy apparatus includes: a first treatment head 01 and a second treatment head 02, and the first treatment head 01 and the second The beam from the treatment head 02 intersects at intersection A.
  • the first treatment head 01 is an X-knife treatment head
  • the second treatment head 02 is a multi-source focusing treatment head, an X-knife treatment head or a conformal intensity-modulating treatment head.
  • the X-knife treatment head is one of the accelerator treatment heads for generating a single narrow X-ray beam.
  • a multi-source focused treatment head is a treatment head that includes a plurality of sources that can be focused at one point.
  • the conformal intensity-modulating treatment head is a treatment head based on the intensity modulated radiation therapy (IMRT) technique, and the shape of the radiation field of the beam that can be used to treat the hair can be determined according to the target area of the affected part. The shape is adjusted.
  • IMRT intensity modulated radiation therapy
  • the emitted beam can intersect the beam emitted by the first treatment head 01 at the intersection, and the dose rate at the intersection A is the same.
  • the dose rate at intersection A is significantly increased compared to radiation therapy with a single treatment head.
  • the first treatment head 01 is an X-knife treatment head, which uses an electron beam target to emit X-rays, there is no cumbersome shielding structure, and the quality thereof is high.
  • the quality of the focused treatment head is light, and the treatment head of the radiotherapy apparatus can be avoided. The quality is too large to ensure that the treatment head can rotate normally.
  • the target or target area to be treated may be coincident with the above-mentioned intersection A to achieve a large dose of radiation therapy.
  • the X-knife treatment head 01 includes a channel collimator 011 for limiting the beam, and an accelerator 012 for emitting an X-ray.
  • the channel collimator 011 can limit the X beam emitted by the accelerator 012 to a single narrow beam.
  • the single narrow beam has a diameter of approximately 6-60 mm.
  • the diameter of the single narrow beam can also be set according to specific needs, which is not specifically limited in the embodiment of the present disclosure.
  • the X-knife treatment head 01 includes an accelerator 012, a channel collimator 011 for limiting the beam, and the above-mentioned accelerator 012 and the above-mentioned channel collimator.
  • Multi-leaf collimator (MLC) 013 between 011.
  • the MLC 013 is used to conform the X-beam emitted by the accelerator 012, and the channel collimator 011 limits the X-beam conformed by the MLC 013.
  • the MLC 013 performs a large range of conformation on the X-beam, that is, the primary conformal shape, and the channel collimator 011 further shapes the X-beam, that is, the secondary conformal shape, so that the X after conformation is formed.
  • the beam is limited to a single narrow beam.
  • channel collimator 011 can be detachably connected to the MLC 013.
  • the two can be snapped or can be bolted.
  • the channel collimator 011 can also move relative to the MLC 013.
  • the MLC 013 is provided with a rail slot
  • the channel collimator 011 is provided with a slider that can be engaged in the rail slot and can slide in the rail slot.
  • the channel collimator 011 can move relative to the MLC 013 in a direction perpendicular to the beam emitted by the accelerator 012 (eg, the Y direction shown in FIG. 2).
  • the channel collimator 011 is moved from the position S1 to the position S2, the channel collimator 011 is located in an area outside the area through which the M-beam 013 conforms to the X-ray.
  • the first treatment head 01 conforms the X-ray beam by the MLC 013, and the first treatment head 01 at this time is similar to the ordinary conformal intensity-modulating treatment head, and the conformal intensity-modulated radiation treatment can be realized.
  • the channel collimator 011 moves from the position S2 to the position S1
  • the channel collimator 011 is located in the region where the X-ray after the MLC 013 conforms.
  • the channel collimator 011 of the first treatment head 01 limits the conformal X-ray beam of the MLC 013 to a single narrow beam.
  • the first treatment head 01 can adjust different modes of radiation therapy as needed.
  • the channel collimator 011 in the above embodiment may include: a plurality of beam channels 011a, and apertures of any two of the plurality of beam channels 011a and/or Different shapes.
  • the channel collimator 011 includes eight different apertures of the beam path 011a.
  • the channel collimator 011 may also include a single beam path 011a that is adjustable in shape and/or size.
  • the shape of the beam passage 011a can be adjusted, for example, the shape of the beam passage 011a can be adjusted from the square shown in FIG. 4 to the hexagon shown in FIG. 5.
  • the size of the beam path 011a can also be adjusted.
  • the channel collimator 011 may include a plurality of collimating blocks, the plurality of collimating blocks enclosing the beam path 011a, and the relative positions of each adjacent two collimating blocks directly Adjustable.
  • the size of the collimating channel can be changed by adjusting the position of the collimating block in the channel collimator 011.
  • the shape and size of the collimating channel 011a can also be adjusted at the same time, which is not specifically limited herein.
  • both the first treatment head 01 and the second treatment head 02 are X-knife treatment heads
  • the X-beams emitted by the accelerators in each treatment head 01 are respectively
  • the channel collimator limits the X-beam to form a single narrow beam.
  • the single narrow beam has a diameter of about 6-10 mm.
  • the beam from the first treatment head 01 and the second treatment head 02 intersects at intersection A, and the dose rate at the intersection A can be the sum of the dose rates of the X-beams from the two X-knife treatment hairs.
  • an X-knife treatment of hair X-ray can reach 1400MU / Min
  • the dose rate is about 3.5Gy / Min
  • the dose rate at the intersection can reach 7Gy / Min, greatly increasing the dose rate at the intersection, Meet the high dose rate requirements of the clinic.
  • the multi-source focusing treatment head described above can focus a plurality of beams onto the intersection point A, which is an X-ray or a gamma beam.
  • the multi-source focusing treatment head 02 may include: a plurality of Co-60 radiation sources 022, The gamma beams emitted by the plurality of Co-60 radiation sources 022 are focused on the intersection A by a collimator (not shown in Fig. 7).
  • the multi-source focusing treatment head 02 emits an X-ray
  • the multi-source focusing treatment head 02 can include an accelerator, and the X-beam emitted by the accelerator is focused by the collimator to the intersection.
  • the multi-source focusing treatment head and the X-knife treatment hair beam are approximately circular at the intersection point, the multi-source focusing treatment head and the X-knife treatment head can cooperate with each other to perform filling radiation therapy on the target area.
  • the filling radiation therapy can irradiate the tumor tissue with high dose, while the surrounding tissue receives less radiation damage, and its precise therapeutic characteristics have a good therapeutic effect on intracranial tumors or small tumors of the head and neck.
  • the fact that the beam is approximately circular at the intersection point means that the orthographic projection of the beam of the treated hair in the first plane is approximately circular, and the first plane is a plane perpendicular to the center line of the beam.
  • the dose rate can reach 3 Gy/Min, and the X-ray treatment of the X-ray can reach 1400 MU/Min, and the dose rate is about 3.5 Gy. /Min.
  • the multi-source focusing treatment head 02 and the X-knife treatment head 01 perform the filling type radiotherapy, as shown in Fig. 7, the beams of the two treatment heads intersect at the intersection point A, and the dose rate at the intersection point A is two treatment heads.
  • the sum of the dose rates can reach 6.5 Gy/Min, which greatly increases the dose rate at the intersection A, meets the clinical high dose rate requirements, and achieves accurate filling treatment of the target area.
  • the conformal intensity-modulating treatment head 02 may include an MLC 023 that can conform to the beam, the beam Is an X beam or a gamma beam.
  • the MLC 023 can be used to form a beam traversable region (also referred to as a radiation field) consistent with the shape of the tumor, through which the beam illuminates the tumor tissue, generally suitable for the treatment of larger body tumors.
  • the beam emitted by the X-knife treatment head 01 intersects the conformal region of the conformal intensity-modulating treatment head 02 at the intersection A, and the dose rate at the intersection A increases.
  • the radiation therapy apparatus may further include: a rotating gantry 10, and the first treatment head 01 and the second treatment head 02 may be disposed on the rotating gantry 10, so that the rotating gantry 10 can drive the first The treatment head 01 and the second treatment head 02 rotate about the rotation axis of the rotating gantry 10.
  • the manner in which the first treatment head 01 and the second treatment head 02 described above can be varied can be various.
  • the first treatment head 01 and/or the second treatment head 02 may reciprocally rotate about a rotation axis of the rotating gantry 10 or continuously rotate 360 degrees around the rotation axis, or may move or oscillate in the axial direction of the rotation shaft of the rotation gantry.
  • the reciprocating rotation may mean rotating a certain angle in a certain direction (for example, clockwise direction) and then rotating in a reverse direction (for example, counterclockwise direction) by a certain angle.
  • non-coplanar illumination of the tumor target or target ie, illuminating the tumor target or target from different directions
  • the dose rate of the target area simultaneously reduces damage to normal tissue.
  • the axial movement or swing of the first treatment head 01 and/or the second treatment head 02 along the rotation axis of the rotating gantry comprises: the first treatment head 01 and/or the second treatment head 02 itself along the rotating machine
  • the axial movement or oscillation of the rotating shaft of the frame also includes the reciprocating movement or swinging of the rotating frame itself around the preset axis, thereby driving the axial movement of the first treatment head 01 and/or the second treatment head 02 along the rotation axis or swing.
  • the preset axis may be parallel to the axis of rotation, or may be the axis of rotation, or the predetermined axis may intersect the axis of rotation.
  • the axial movement or oscillation of the first treatment head 01 and/or the second treatment head 02 itself along the rotation axis of the rotating gantry comprises: the first treatment head 01 and/or the second treatment head 02 itself along the rotating gantry
  • the rotating shaft performs an arc motion or a linear motion, or swings in the axial direction of the rotating shaft of the rotating frame with the treating head itself as a pivot axis.
  • the rotating frame 10 may be provided with an arc-shaped guide groove or a linear guide groove extending along the axial direction of the rotating shaft, and the first treatment head 01 and/or the second treatment head 02 are connected to the slider.
  • the slider is snapped into the rail slot and is slidable within the rail slot.
  • the treatment head can perform an arc motion or a linear motion along the rotation axis of the rotating gantry.
  • the rotating frame is fixed with a connecting shaft perpendicular to the rotating shaft of the rotating frame, and the treatment head is rotatably coupled to the connecting shaft and is rotatable about the connecting shaft.
  • the treatment head can swing itself in the axial direction of the rotation axis of the rotating frame by itself.
  • the rotating frame may be a drum frame, a C-shaped arm or a drum-shaped frame, and the like, which is not specifically limited in the embodiment of the present disclosure.
  • the positional relationship between the first treatment head 01 and the second treatment head 02 described above can also be varied.
  • the radial angle between the first treatment head 01 and the center line of the second treatment head 02 beam may be set to be less than or equal to 180°, and the first treatment head 01 and the second treatment head 02 beam center line may be The axial angle between them is set to be less than or equal to 90°.
  • the beam center line of the first treatment head 01 is viewed from a section along the rotation axis of the rotating gantry (where the intersection point A is on the rotation axis), that is, a section perpendicular to the rotation axis.
  • the angle ⁇ between the beam centerlines of the second treatment head 02 that is, the radial angle ⁇ is less than or equal to 180°, for example, the radial angle ⁇ is 30°, 45°, 60°, 75°, 90°, 105°, 120°, 135°, 150°, 165° or 180°.
  • the radial angle can be an orthographic projection of the beam centerline of the first treatment head 01 on the first section, and the beam centerline of the second treatment head 02 is on the first section.
  • the angle between the orthographic projections, the first section being a section perpendicular to the axis of rotation.
  • the radial angle ⁇ may also be 30° or less, 45° or less, 60° or less, 75° or less, 90° or less, 105° or less, 120° or less, and 135° or less. , less than or equal to 150 ° or less than or equal to 165 ° and so on.
  • the beam center line of the first treatment head 01 and the second treatment head 02 are seen from the section passing through the rotation axis m of the rotating gantry 10 (i.e., the section in which the rotation axis m is located).
  • the angle ⁇ between the bundle centerlines that is, the axial angle ⁇ is less than or equal to 90°, for example, the axial angle ⁇ is 30°, 45°, 60°, 75° or 90°.
  • the axial angle can be an orthographic projection of the beam centerline of the first treatment head 01 on the second section, and the beam centerline of the second treatment head 02 on the second section.
  • An angle between the orthographic projections, the second section being a section passing through the axis of rotation m.
  • the radiation therapy apparatus may further include: a third treatment head 03, the beam emitted by the third treatment head 03 intersecting the beam emitted by the first treatment head 01 and the second treatment head 02 at the intersection A.
  • the third treatment head 03 can be an X-knife treatment head, a multi-source focusing treatment head or a conformal intensity-modulating treatment head. In this way, the dose rate at the intersection A can be further increased.
  • the first treatment head 01, the second treatment head 02, and the third treatment head 03 are both X-knife treatment heads, and the three X-knife treatment hair beams intersect at the intersection point A. .
  • the third treatment head 03 described above may be disposed on the rotating gantry 10 like the first treatment head 01 and/or the second treatment head 02, or may be disposed at other positions as needed.
  • the rotating gantry 10 can also rotate the third treatment head 03 about the rotation axis of the rotating gantry 10.
  • the manner in which the third treatment head 03 moves can be varied.
  • the third treatment head 03 can be reciprocally rotated about a rotation axis or continuously rotated 360° around the rotation axis, or can be moved or oscillated in the axial direction of the rotation axis of the rotary gantry.
  • the first treatment head 01 and the second treatment head 02 can be combined to achieve non-coplanar illumination of the target or target to be treated, so that the tumor can be enlarged by the technical solution of the embodiments of the present disclosure.
  • the dose rate of the target area simultaneously reduces damage to normal tissue.
  • the first treatment head 01, the second treatment head 02, and the third treatment head 03 are disposed on a fixture 20 that is coupled to the rotating gantry 10.
  • the radial angle between the adjacent two treatment heads is 5°-45°, That is, from the cross section in the direction of the rotation axis of the rotating gantry (where the intersection point is on the rotation axis), the first treatment head 01, the second treatment head 02, and the third treatment head 03 are adjacent to the two treatments.
  • the angle between the center line of the beam of the head is 5°-45°, that is, the radial angle is 5°-45°, for example, the radial angle is 5°, 10°, 15°, 20°, 25°. , 30° or 45°.
  • the radiotherapy apparatus may further include a fourth treatment head, a fifth treatment head, ..., an Nth treatment head (N is an integer greater than 3), which is not specifically limited in the embodiment of the present disclosure.
  • N is an integer greater than 3
  • the greater the number of treatment heads included in the radiation therapy device the smaller the radial angle between adjacent treatment points.
  • the radial angle between two adjacent treatment heads may be the same or different.
  • the fourth treatment head, the fifth treatment head, ..., the Nth treatment head may all be X-knife treatment heads.
  • the first treatment head 01 is an X-knife treatment head
  • the second treatment head 02 is a multi-source focusing treatment head
  • the third treatment head 03, and the fourth treatment head 04 are X-knife treatment heads.
  • the rotating frame 10 is a roller frame
  • the position of the X-knife treatment head (ie, the first treatment head 01, the third treatment head 03, and the fourth treatment head 04) on the drum frame 10 can be set.
  • the quality of the source focusing treatment head 02 is balanced to facilitate rotation of the drum frame 10.
  • the present disclosure also provides a radiation therapy system, which can include a radiotherapy bed and a radiation therapy device, which can be any of the radiation therapy devices of any of the foregoing embodiments of the present disclosure, such as any of Figures 1-13.
  • a radiation therapy system which can include a radiotherapy bed and a radiation therapy device, which can be any of the radiation therapy devices of any of the foregoing embodiments of the present disclosure, such as any of Figures 1-13.
  • the radiation therapy device shown shown.
  • association relationship describing an association object, indicating that there may be three relationships, for example, A and/or B, which may indicate that A exists separately. There are three cases of A and B, and B alone.
  • character "/" in this article generally indicates that the contextual object is an "or" relationship.

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Abstract

一种放射治疗设备及系统，放射治疗设备包括：第一治疗头(01)和第二治疗头(02)，并且第二治疗头(02)与第一治疗头(01)发出的射束相交于交点；其中，第一治疗头(01)为X刀治疗头，第二治疗头(02)为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。放射治疗设备可以增大交点处的剂量率。

Description

一种放射治疗设备及系统
本公开要求于2018年1月15日提交的申请号为201810037191.7、发明名称为“一种放射治疗系统”的中国专利申请的优先权，其全部内容通过引用结合在本公开中。
技术领域
本公开涉及医疗器械技术领域，尤其涉及一种放射治疗设备及系统。
背景技术
放射治疗已成为治疗恶性肿瘤的主要手段之一。以放射线的种类来分，主流的放射治疗设备包括γ射线放疗设备和X射线放疗设备。
在实际放射治疗过程中，无论采用何种放疗设备，医师通常希望肿瘤靶区的剂量率越大越好，肿瘤靶区的剂量率越大，越能够摧毁肿瘤细胞的DNA链，治疗效果越好。其中，剂量率是指肿瘤靶区单位时间内接受的剂量。
发明内容
本公开实施例提供了一种放射治疗设备，包括：第一治疗头；第二治疗头，所述第二治疗头与所述第一治疗头发出的射束相交于交点；其中，所述第一治疗头为X刀治疗头，所述第二治疗头为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。
在一实施例中，所述X刀治疗头包括：用于对射束进行限束的通道准直器；其中，所述通道准直器包括：多个射束通道，任意两个所述射束通道的孔径和形状中的至少一种不同；或者，所述通道准直器包括单个射束通道，所述单个射束通道的形状和/或大小可调。
在一实施例中，所述X刀治疗头还包括：用于发出所述射束的加速器。
在一实施例中，所述X刀治疗头还包括：用于对所述射束适形的多叶准直器，所述多叶准直器与所述通道准直器连接；其中，所述通道准直器用于对所述多叶准直器适形后的射束进行限束。
在一实施例中，所述通道准直器与所述多叶准直器可拆卸连接。
在一实施例中，所述通道准直器相对所述多叶准直器可移动。
在一实施例中，所述第一治疗头和/或所述第二治疗头设置在旋转机架上。
在一实施例中，所述第一治疗头和/或所述第二治疗头可绕所述旋转机架的旋转轴往复旋转或360°连续旋转。
在一实施例中，所述第一治疗头和/或所述第二治疗头可沿所述旋转机架的旋转轴的轴向移动或摆动。
在一实施例中，所述第一治疗头的射束中心线与所述第二治疗头射束中心线之间的径向夹角小于等于180°；其中，所述径向夹角为：所述第一治疗头的射束中心线在第一截面的正投影与所述第二治疗头的射束中心线在所述第一截面的正投影的夹角，所述第一截面为垂直于所述旋转轴的截面。
在一实施例中，所述第一治疗头的射束中心线与所述第二治疗头的射束中心线之间的轴向夹角小于等于90°；其中，所述轴向夹角为：所述第一治疗头的射束中心线在第二截面的正投影与所述第二治疗头的射束中心线在所述第二截面的正投影的夹角，所述第二截面为平行于所述旋转轴或经过所述旋转轴的截面。
在一实施例中，所述放射治疗设备还包括：第三治疗头，所述第三治疗头发出的射束与所述第一治疗头、所述第二治疗头发出的射束相交于所述交点；其中，所述第三治疗头为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。
在一实施例中，所述第二治疗头为X刀治疗头，所述第三治疗头为X刀治疗头。
在一实施例中，所述第一治疗头和/或所述第二治疗头和/或所述第三治疗头设置在旋转机架上。
在一实施例中，所述第一治疗头和/或所述第二治疗头和/或所述第三治疗头可沿所述旋转机架的旋转轴的轴向移动或摆动。
在一实施例中，所述第一治疗头、第二治疗头、第三治疗头设置在一个固定装置上，所述固定装置与所述旋转机架连接。
在一实施例中，相邻的两个治疗头之间的径向夹角为5°-45°；所述径向夹角为：相邻的两个治疗头的射束中心线在第一截面的正投影的夹角，所述第一截面为垂直于所述旋转轴的截面。
在一实施例中，所述旋转机架为滚筒机架或者C形臂。
在一实施例中，所述多源聚焦治疗头发出X射束或γ射束，所述适形调强 治疗头发出X射束或γ射束。
本公开实施例提供了一种放射治疗系统，包括：治疗床，以及如上所述的放射治疗设备。
附图说明
为了更清楚地说明本公开实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本公开的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本公开实施例提供的一种放射治疗设备的结构示意图；
图2是本公开实施例提供的一种X刀治疗头的结构示意图；
图3是本公开实施例提供的一种通道准直器的结构示意图；
图4是本公开实施例提供的另一种通道准直器的结构示意图；
图5本公开实施例提供的又一种通道准直器的结构示意图；
图6是本公开实施例中第二治疗头为X刀治疗头时放射治疗设备的结构示意图；
图7是本公开实施例中第二治疗头为多源聚焦治疗头时放射治疗设备的结构示意图；
图8是本公开实施例中第二治疗头为适形调强治疗头时放射治疗设备的结构示意图；
图9是本公开实施例中第一治疗头与第二治疗头射束中心线之间的轴向夹角示意图；
图10是本公开实施例提供的一种包括第三治疗头的放射治疗设备；
图11是本公开实施例中第二治疗头和第三治疗头为X刀治疗头时放射治疗设备的结构示意图；
图12是本公开实施例中第一治疗头、第二治疗头和第三治疗头设置在固定装置时放射治疗设备的结构示意图；
图13是本公开实施例中第一治疗头为X刀治疗头、第二治疗头为多源聚焦治疗头、第三治疗头和第四治疗头为X刀治疗头时放射治疗设备的结构示意图。
具体实施方式
为了使本公开的目的、技术方案及优点更加清楚明白，以下结合附图及实施例，对本公开进行进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本公开，并不用于限定本公开。
目前，对于γ射线放疗设备，由于钴-60(Co-60)具有放射性，其对放疗设备的屏蔽性要求较高，若使用更多的放射源来增大剂量率，则γ射线放疗设备的屏蔽就需要加厚，治疗头的质量就会增加，不利于实现治疗头的旋转聚焦。对于X射线放疗设备，医师一般需要通过多次或更长时间的照射来增大剂量率，而多次和更长时间照射容易影响放射治疗的精度。
图1为本公开实施例提供的一种放射治疗设备的结构示意图，如图1所示，该放疗设备包括：第一治疗头01和第二治疗头02，并且第一治疗头01与第二治疗头02发出的射束相交于交点A。其中，第一治疗头01为X刀治疗头，第二治疗头02为多源聚焦治疗头、X刀治疗头或者适形调强治疗头。
其中，X刀治疗头为加速器治疗头中的一种，用于产生单窄X射束。多源聚焦治疗头是一种包括多个放射源的治疗头，该多个放射源的射束可以聚焦于一点。适形调强治疗头是一种基于适形调强放疗(intensity modulated radiation therapy，IMRT)技术的治疗头，该适形调强治疗头发出的射束的辐射野的形状可以根据患部靶区的形状进行调整。
在本公开实施例中，不论第二治疗头02为何种类型的治疗头，其发出的射束均都可以与第一治疗头01发出的射束相交于交点，交点A处的剂量率为第一治疗头01和第二治疗头02的剂量率之和。与使用单一治疗头进行放射治疗相比，交点A处的剂量率会明显增大。另外，由于第一治疗头01为X刀治疗头，其采用电子束打靶发出X射线，因此没有笨重的屏蔽结构，其质量较多源聚焦治疗头的质量轻，可以避免放射治疗设备的治疗头的质量过大，保证治疗头可以正常旋转。
在使用上述放射治疗设备进行肿瘤治疗时，可以将待治疗的靶点或者靶区与上述交点A重合，以实现大剂量的放射治疗。
在一种实施例中，如图1所示，X刀治疗头01包括：用于对射束进行限束的通道准直器011，以及用于发出X射束的加速器012。其中，通道准直器011可以将加速器012发出的X射束限束为单窄射束。示例性的，该单窄射束 的直径大约为6-60mm。当然对于单窄射束的直径也可以根据具体需要进行设定，本公开实施例对此不作具体限定。
在另一种实施例中，如图2所示，X刀治疗头01包括：加速器012、用于对射束进行限束的通道准直器011，以及位于上述加速器012和上述通道准直器011之间的多叶准直器(multi-leaf collimator，MLC)013。该MLC 013用于对加速器012发出的X射束进行适形，通道准直器011对MLC 013适形后的X射束进行限束。也就是说，MLC 013对X射束进行较大范围的适形，即初级适形，通道准直器011对X射束做进一步束形，即次级适形，从而将适形后的X射束限束为单窄射束。
进一步的，通道准直器011可以与MLC 013可拆卸连接。例如，两者可以卡接或者可以通过螺栓连接。
可选的，通道准直器011也可以相对于MLC 013移动。例如，MLC 013上设置有导轨槽，通道准直器011上设置有滑块，该滑块可以卡接在该导轨槽内，且能够在该导轨槽内滑动。
如图2所示，通道准直器011可以沿垂直于加速器012发出的射束的方向(例如图2所示的Y方向)相对MLC 013运动。当通道准直器011从位置S1移动至位置S2处时，通道准直器011位于MLC 013适形后的X射束所经过的区域之外的区域。此时，第一治疗头01通过MLC 013对X射束进行适形，这时的第一治疗头01类似于普通的适形调强治疗头，可以实现适形调强放射治疗。当通道准直器011从位置S2移动至位置S1处时，通道准直器011位于MLC 013适形后的X射束所经过的区域内。此时，第一治疗头01的通道准直器011将MLC 013适形后的X射束限束为单窄射束。由此，第一治疗头01可根据需要调整不同方式的放射治疗。
可选的，如图3所示，上述实施例中的通道准直器011可以包括：多个射束通道011a，该多个射束通道011a中任意两个射束通道011a的孔径和/或形状不同。例如在图3所示的结构中，该通道准直器011包括8个不同孔径的射束通道011a。
或者，如图4和图5所示，该通道准直器011也可以包括：形状和/或大小可调的单个射束通道011a。示例的，射束通道011a的形状可以进行调整，例如，可以将射束通道011a的形状由图4所示的方形调整为图5所示的六边形。射束通道011a的大小也可以进行调整。例如，参考图4和图5，该通道准直器 011可以包括多个准直块，该多个准直块围成该射束通道011a，且每相邻两个准直块直接的相对位置可调。由此，可以通过调整通道准直器011中的准直块的位置来改变准直通道的大小。当然也可以同时调整准直通道011a的形状和大小，这里不做具体限定。
在第一治疗头01和第二治疗头02均为X刀治疗头的情况下，在一实施例中，如图6所示，每个治疗头01中的加速器发出的X射束分别经各自的通道准直器对X射束进行限束，形成单窄射束。该单窄射束的直径为6-10mm左右。第一治疗头01和第二治疗头02发出的射束相交于交点A处，该交点A处的剂量率可以为两个X刀治疗头发出的X射束的剂量率之和。通常，一个X刀治疗头发出的X射束可以达到1400MU/Min，剂量率大概为3.5Gy/Min，则交点处的剂量率可以达到7Gy/Min，极大的提高了交点处的剂量率，满足临床的高剂量率要求。
这里还需要说明的是，上述多源聚焦治疗头可以将多个射束聚焦到上述交点A处，该多个射束为X射束或γ射束。
当第二治疗头02为多源聚焦治疗头，且多源聚焦治疗头发出γ射束时，如图7所示，该多源聚焦治疗头02可以包括：多个Co-60放射源022，多个Co-60放射源022发出的γ射束经准直器(图7未示出)聚焦于交点A。当多源聚焦治疗头02发出X射束时，该多源聚焦治疗头02可以包括：加速器，加速器发出的X射束经准直器聚焦于交点。
由于多源聚焦治疗头和X刀治疗头发出的射束在交点处均近似圆形，因此，多源聚焦治疗头和X刀治疗头可以相互配合对靶区进行填充式放射治疗。该填充式放射治疗可以对肿瘤组织进行高剂量照射，而周边组织受到的辐射损伤较小，其精准的治疗特性对于颅内肿瘤或者头颈部较小的肿瘤具有很好的治疗效果。其中，射束在交点处均近似圆形可以是指：治疗头发出的射束在第一平面内的正投影近似圆形，该第一平面为垂直于射束中心线的平面。
以第二治疗头02为发出γ射束的多源聚焦治疗头为例，其剂量率可以达到3Gy/Min，X刀治疗头发出的X射束可以达到1400MU/Min，剂量率大概为3.5Gy/Min。在多源聚焦治疗头02和X刀治疗头01进行填充式的放射治疗时，如图7所示，两个治疗头的射束相交于交点A，交点A处的剂量率为两个治疗头剂量率的和，可以达到6.5Gy/Min，极大的提高了交点A处的剂量率，满足临床的高剂量率要求，也实现了对靶区的精确填充治疗。
这里还需要说明的是，当第二治疗头02为适形调强治疗头时，参考图8，该适形调强治疗头02可以包括可对射束进行适形的MLC 023，该射束为X射束或γ射束。利用MLC 023可形成与肿瘤形状一致的射束可穿过区域(也称为辐射野)，射束穿过该区域照射肿瘤组织上，一般适用于较大的体部肿瘤的治疗。如图8所示，X刀治疗头01发出的射束与适形调强治疗头02的适形区域相交于交点A，交点A处的剂量率增大。
又如图1所示，该放射治疗设备还可以包括：旋转机架10，第一治疗头01和第二治疗头02可以设置在旋转机架10上，从而转转机架10可以带动第一治疗头01和第二治疗头02绕旋转机架10的旋转轴旋转。
当然，也可以仅将第一治疗头01和第二治疗头02中的一个设置在旋转机架10上，另一个设置在其他位置，例如，另一个设置在固定机架上。本公开实施例对此不做具体限定。
上述第一治疗头01和第二治疗头02的运动方式可以是多种多样的。第一治疗头01和/或第二治疗头02可以绕旋转机架10的旋转轴往复旋转或者绕旋转轴360°连续旋转，也可以沿旋转机架的旋转轴的轴向移动或摆动。其中，往复旋转可以是指沿某个方向(例如顺时针方向)旋转一定角度后再沿反方向(例如逆时针方向)旋转一定角度。
通过这些运动方式，可实现对肿瘤靶区或者靶点的非共面照射(即从不同的方向照射肿瘤靶区或者靶点)，这样，通过本公开实施例的技术方案，可以在增大肿瘤靶区的的剂量率的同时减少对正常组织的伤害。
可选的，上述第一治疗头01和/或第二治疗头02沿旋转机架的旋转轴的轴向移动或摆动包括：第一治疗头01和/或第二治疗头02自身沿旋转机架的旋转轴的轴向移动或者摆动，也包括旋转机架自身围绕预设轴进行往复移动或摆动，从而带动第一治疗头01和/或第二治疗头02沿旋转轴的轴向移动或摆动。该预设轴可以平行线与该旋转轴，或者可以为该旋转轴，或者该预设轴可以与该旋转轴相交。
其中，第一治疗头01和/或第二治疗头02自身沿旋转机架的旋转轴的轴向移动或者摆动包括：第一治疗头01和/或第二治疗头02自身沿旋转机架的旋转轴进行弧线运动或者直线运动，或者，以治疗头自身为枢转轴，沿旋转机架的旋转轴的轴向进行摆动。
示例的，该旋转机架10上可以设置有沿其旋转轴的轴向延伸的弧线形导 轨槽或直线型导轨槽，第一治疗头01和/或第二治疗头02与滑块连接，该滑块卡接在导轨槽内，且能够在该导轨槽内滑动。由此，治疗头可以沿旋转机架的旋转轴进行弧线运动或者直线运动。
或者，旋转机架上固定有连接轴，该连接轴垂直于旋转机架的旋转轴，治疗头可以与连接轴转动连接，能够以该连接轴为轴旋转。由此，治疗头即可以自身为枢转轴沿旋转机架的旋转轴的轴向进行摆动
在本公开实施例中，旋转机架可以为滚筒机架、C形臂或鼓形机架等等，本公开实施例不做具体限定。
上述第一治疗头01和第二治疗头02之间的位置关系也可以是多种多样的。可以将第一治疗头01与第二治疗头02射束中心线之间的径向夹角设置为小于等于180°，也可以将第一治疗头01与第二治疗头02射束中心线之间的轴向夹角设置为小于等于90°。
如图1所示，从沿旋转机架的旋转轴(这里交点A位于旋转轴上)方向的截面(即垂直于该旋转轴的截面)来看，第一治疗头01的射束中心线与第二治疗头02的射束中心线之间的夹角α，即径向夹角α小于等于180°，例如径向夹角α为30°、45°、60°、75°、90°、105°、120°、135°、150°、165°或者180°。结合图1可知，该径向夹角可以是指：第一治疗头01的射束中心线在第一截面上的正投影，与第二治疗头02的射束中心线在第一截面上的正投影之间的夹角，该第一截面为垂直于该旋转轴的截面。
示例的，该径向夹角α也可以小于等于30°、小于等于45°、小于等于60°、小于等于75°、小于等于90°、小于等于105°、小于等于120°、小于等于135°、小于等于150°或小于等于165°等。
如图9所示，从穿过旋转机架10的旋转轴m的截面(即该旋转轴m所在的截面)来看，第一治疗头01的射束中心线与第二治疗头02的射束中心线之间的夹角β，即轴向夹角β小于等于90°，例如轴向夹角β为30°、45°、60°、75°或者90°。结合图9可知，该轴向夹角可以是指：第一治疗头01的射束中心线在第二截面上的正投影，与第二治疗头02的射束中心线在第二截面上的正投影之间的夹角，该第二截面为经过该旋转轴m的截面。
如图10所示，放射治疗设备还可以包括：第三治疗头03，第三治疗头03发出的射束与第一治疗头01、第二治疗头02发出的射束相交于交点A。其中，第三治疗头03可以为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。这 样，可以进一步增加交点A处的剂量率。
在一实施例中，如图11所示，第一治疗头01、第二治疗头02和第三治疗头03均为X刀治疗头，三个X刀治疗头发出的射束相交于交点A。
上述第三治疗头03可以与第一治疗头01和/或第二治疗头02一样，设置在旋转机架10上，也可以根据需要设置在其他位置。
若第三治疗头03设置在旋转机架10上，则旋转机架10也可以带动第三治疗头03绕旋转机架10的旋转轴旋转。同样，第三治疗头03的运动方式可以是多种多样的。第三治疗头03可以绕旋转轴往复旋转或者绕旋转轴360°连续旋转，也可以沿旋转机架的旋转轴的轴向移动或摆动。
通过这些运动方式，可以与第一治疗头01、第二治疗头02配合，实现对待治疗靶区或者靶点的非共面照射，这样，通过本公开实施例的技术方案，可以在增大肿瘤靶区的的剂量率的同时减少对正常组织的伤害。
在另一实施例中，如图12所示，第一治疗头01、第二治疗头02和第三治疗头03设置在一个固定装置20上，固定装置20与旋转机架10连接。
可选的，如图12所示，第一治疗头01、第二治疗头02和第三治疗头03中，相邻的两个治疗头之间的径向夹角为5°-45°，也就是说，从沿旋转机架的旋转轴(这里交点位于旋转轴上)方向的截面来看，第一治疗头01、第二治疗头02和第三治疗头03中，相邻两个治疗头的射束中心线之间的夹角为5°-45°，即径向夹角为5°-45°，例如径向夹角为5°、10°、15°、20°、25°、30°或者45°。
当然，放射治疗设备还可以包括第四治疗头，第五治疗头，……，第N治疗头(N为大于3的整数)，本公开实施例对此不做具体限定。并且，放射治疗设备中包括的治疗头的个数越多，相邻两个治疗头之间的径向夹角即越小。
这里需要说明的是，相邻两个治疗头之间的径向夹角可以相同，也可以不同。
这里，第四治疗头，第五治疗头，……，第N治疗头可以均为X刀治疗头。
示例性的，如图13所示，第一治疗头01为X刀治疗头、第二治疗头02为多源聚焦治疗头、第三治疗头03和第四治疗头04为X刀治疗头，且旋转机架10为滚筒机架时，可以通过设置上述X刀治疗头(即第一治疗头01、第三治疗头03和第四治疗头04)在滚筒机架10上的位置，与多源聚焦治疗头02 的质量达到平衡，以方便滚筒机架10的旋转。
本公开还提供了一种放射治疗系统，该系统可以包括放疗床和放射治疗设备，该放射治疗设备可以为本公开前述实施例任一所述的放射治疗设备，例如图1至图13任一所示的放射治疗设备。
需要说明的是，本公开实施例中的术语“和/或”，仅仅是一种描述关联对象的关联关系，表示可以存在三种关系，例如，A和/或B，可以表示：单独存在A，同时存在A和B，单独存在B这三种情况。另外，本文中字符“/”，一般表示前后关联对象是一种“或”的关系。
虽然本公开所揭露的实施方式如上，但如上内容仅为便于理解本公开而采用的实施方式，并非用以限定本公开。任何本公开所属领域内的技术人员，在不脱离本公开所揭露的精神和范围的前提下，可以在实施的形式及细节上进行任何的修改与变化，但本公开的专利保护范围，仍须以所附的权利要求书所界定的范围为准。

Claims (20)

  1. 一种放射治疗设备，包括：
    第一治疗头(01)；
    第二治疗头(02)，所述第二治疗头(02)与所述第一治疗头(01)发出的射束相交于交点；
    其中，所述第一治疗头(01)为X刀治疗头，所述第二治疗头(02)为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。
  2. 根据权利要求1所述的放射治疗设备，其中，所述X刀治疗头包括：用于对射束进行限束的通道准直器(011)；
    其中，所述通道准直器(011)包括：多个射束通道，任意两个所述射束通道的孔径和形状中的至少一种不同；或者，所述通道准直器(011)包括：单个射束通道，所述单个射束通道的形状和大小中的至少一种可调。
  3. 根据权利要求2所述的放射治疗设备，其中，所述X刀治疗头还包括：用于发出所述射束的加速器(012)。
  4. 根据权利要求2所述的放射治疗设备，其中，所述X刀治疗头还包括：用于对所述射束适形的多叶准直器(013)，所述多叶准直器(013)与所述通道准直器(011)连接；
    其中，所述通道准直器(011)用于对所述多叶准直器(013)适形后的射束进行限束。
  5. 根据权利要求4所述的放射治疗设备，其中，所述通道准直器(011)与所述多叶准直器(013)可拆卸连接。
  6. 根据权利要求4所述的放射治疗设备，其中，所述通道准直器(011)相对所述多叶准直器(013)可移动。
  7. 根据权利要求1所述的放射治疗设备，其中，
    所述第一治疗头(01)和所述第二治疗头(02)中的至少一个治疗头设置 在旋转机架(10)上。
  8. 根据权利要求1所述的放射治疗设备，其中，所述第一治疗头(01)和所述第二治疗头(02)中的至少一个治疗头可绕旋转机架(10)的旋转轴往复旋转或360°连续旋转。
  9. 根据权利要求1所述的放射治疗设备，其中，所述第一治疗头(01)和所述第二治疗头(02)中的至少一个治疗头可沿旋转机架(10)的旋转轴的轴向移动或摆动。
  10. 根据权利要求7所述的放射治疗设备，其中，所述第一治疗头(01)的射束中心线与所述第二治疗头(02)的射束中心线之间的径向夹角小于等于180°；
    其中，所述径向夹角为：所述第一治疗头(01)的射束中心线在第一截面的正投影与所述第二治疗头(02)的射束中心线在所述第一截面的正投影的夹角，所述第一截面为垂直于所述旋转轴的截面。
  11. 根据权利要求7所述的放射治疗设备，其中，所述第一治疗头(01)的射束中心线与所述第二治疗头(02)的射束中心线之间的轴向夹角小于等于90°；
    其中，所述轴向夹角为：所述第一治疗头(01)的射束中心线在第二截面的正投影与所述第二治疗头(02)的射束中心线在所述第二截面的正投影的夹角，所述第二截面为平行于所述旋转轴或经过所述旋转轴的截面。
  12. 根据权利要求1所述的放射治疗设备，其中，所述放射治疗设备还包括：
    第三治疗头(03)，所述第三治疗头(03)发出的射束与所述第一治疗头(01)、所述第二治疗头(02)发出的射束相交于所述交点；
    其中，所述第三治疗头(03)为X刀治疗头、多源聚焦治疗头或者适形调强治疗头。
  13. 根据权利要求12所述的放射治疗设备，其中，所述第二治疗头(02)为X刀治疗头，所述第三治疗头(03)为X刀治疗头。
  14. 根据权利要求12所述的放射治疗设备，其中，
    所述第一治疗头(01)、所述第二治疗头(02)和所述第三治疗头(03)中的至少一个治疗头设置在旋转机架(10)上。
  15. 根据权利要求14所述的放射治疗设备，其中，所述第一治疗头(01)、所述第二治疗头(02)和所述第三治疗头(03)中的至少一个治疗头可沿所述旋转机架(10)的旋转轴的轴向移动或摆动。
  16. 根据权利要求14所述的放射治疗设备，其中，
    所述第一治疗头(01)、所述第二治疗头(02)和所述第三治疗头(03)设置在一个固定装置(20)上，所述固定装置(20)与所述旋转机架(10)连接。
  17. 根据权利要求16所述的放射治疗设备，其中，相邻的两个治疗头的射束中心线之间的径向夹角为5°-45°；
    其中，所述径向夹角为：相邻的两个治疗头的射束中心线在第一截面的正投影的夹角，所述第一截面为垂直于所述旋转轴的截面。
  18. 根据权利要求7所述的放射治疗设备，其中，所述旋转机架(10)为滚筒机架或者C形臂。
  19. 根据权利要求1所述的放射治疗设备，其中，所述多源聚焦治疗头发出X射束或γ射束，所述适形调强治疗头发出X射束或γ射束。
  20. 一种放射治疗系统，包括：治疗床，以及如权利要求1至19任一所述的放射治疗设备。
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