WO2019103475A3 - Hla genotyping kit using real-time polymerase chain reaction - Google Patents

Hla genotyping kit using real-time polymerase chain reaction Download PDF

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Publication number
WO2019103475A3
WO2019103475A3 PCT/KR2018/014407 KR2018014407W WO2019103475A3 WO 2019103475 A3 WO2019103475 A3 WO 2019103475A3 KR 2018014407 W KR2018014407 W KR 2018014407W WO 2019103475 A3 WO2019103475 A3 WO 2019103475A3
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WO
WIPO (PCT)
Prior art keywords
hla
real
chain reaction
polymerase chain
time polymerase
Prior art date
Application number
PCT/KR2018/014407
Other languages
French (fr)
Korean (ko)
Other versions
WO2019103475A2 (en
Inventor
고웅열
김주형
고아라
이은지
임희경
김원동
Original Assignee
(주)오상헬스케어
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Publication date
Application filed by (주)오상헬스케어 filed Critical (주)오상헬스케어
Publication of WO2019103475A2 publication Critical patent/WO2019103475A2/en
Publication of WO2019103475A3 publication Critical patent/WO2019103475A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Provided are a HLA allele genotyping kit comprising: a primer set allowing the specific amplification of an HLA allele for one or more genes selected from among HLA-A, HLA-B, HLA-DRB1, HLA-C, HLA-DQB1, and HLA-DQA1 through real-time polymerase chain reaction; and a probe capable of probing the product amplified by the real-time polymerase chain reaction, and a method for determining an HLA allele by using the same.
PCT/KR2018/014407 2017-11-23 2018-11-22 Hla genotyping kit using real-time polymerase chain reaction WO2019103475A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0157699 2017-11-23
KR1020170157699A KR20190059780A (en) 2017-11-23 2017-11-23 Kit for hla allele type using real time pcr method

Publications (2)

Publication Number Publication Date
WO2019103475A2 WO2019103475A2 (en) 2019-05-31
WO2019103475A3 true WO2019103475A3 (en) 2019-07-18

Family

ID=66631596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2018/014407 WO2019103475A2 (en) 2017-11-23 2018-11-22 Hla genotyping kit using real-time polymerase chain reaction

Country Status (2)

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KR (1) KR20190059780A (en)
WO (1) WO2019103475A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102475292B1 (en) * 2020-09-03 2022-12-08 주식회사 엔젠바이오 Composition for Amplifying HLA genes and Uses thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100028861A1 (en) * 2003-12-25 2010-02-04 Canon Kabushiki Kaisha Probe set and method for identifying hla allele
KR20100131350A (en) * 2009-06-05 2010-12-15 가톨릭대학교 산학협력단 Automatic kit for hla alle typing using real time pcr method
KR101320622B1 (en) * 2013-03-08 2013-10-23 (주)진스랩 Hla genotyping method and kit using speed multiplex pcr method
US20140206005A1 (en) * 2011-07-21 2014-07-24 Genodive Pharma Inc. Method and Kit for DNA Typing of HLA Gene
US20170029885A1 (en) * 2013-11-27 2017-02-02 Genodive Pharma Inc. Simple Method and Kit for DNA Typing of HLA Genes by High-Throughput Massively Parallel Sequencer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100028861A1 (en) * 2003-12-25 2010-02-04 Canon Kabushiki Kaisha Probe set and method for identifying hla allele
KR20100131350A (en) * 2009-06-05 2010-12-15 가톨릭대학교 산학협력단 Automatic kit for hla alle typing using real time pcr method
US20140206005A1 (en) * 2011-07-21 2014-07-24 Genodive Pharma Inc. Method and Kit for DNA Typing of HLA Gene
KR101320622B1 (en) * 2013-03-08 2013-10-23 (주)진스랩 Hla genotyping method and kit using speed multiplex pcr method
US20170029885A1 (en) * 2013-11-27 2017-02-02 Genodive Pharma Inc. Simple Method and Kit for DNA Typing of HLA Genes by High-Throughput Massively Parallel Sequencer

Also Published As

Publication number Publication date
KR20190059780A (en) 2019-05-31
WO2019103475A2 (en) 2019-05-31

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