WO2019098410A1

WO2019098410A1 - Photographing time display device, and device and method for diagnosing sleep-disordered breathing by using time display device

Info

Publication number: WO2019098410A1
Application number: PCT/KR2017/012985
Authority: WO
Inventors: 한병삼
Original assignee: 주식회사 선테크; 한병삼
Priority date: 2017-11-15
Filing date: 2017-11-16
Publication date: 2019-05-23
Also published as: KR20190055548A

Abstract

The present invention relates to a photographing time display device and a device and method for diagnosing sleep-disordered breathing by using a time display device, the photographing time display device comprising: an electromyogram detection unit for detecting an electromyogram of an examinee; an oxygen saturation detection unit for detecting an oxygen saturation of an examinee; a breathing state detection unit for detecting a breathing state of an examinee; a signal conversion unit for converting detection results of the electromyogram detection unit, the oxygen saturation detection unit, and the breathing state detection unit into digital signals; a calculation processing unit for receiving and performing calculation of an electromyogram, an oxygen saturation, and a breathing state signal which have been converted into digital signals by the signal conversion unit, so as to obtain an apnea index; and a display unit for displaying an apnea index obtained by the calculation processing unit while indicating, by color, that photographing is possible.

Description

APPARATUS AND METHOD FOR DIAGNOSING REMOTE RESPIRATORY DEPRESSION USING SIGHTING TIME DISPLAY DEVICE

The present invention relates to an apparatus and method for diagnosing a sleeping breath disorder using a time display apparatus and a time display apparatus, and more particularly, to an apparatus and method for detecting a sleeping state and a respiratory disorder, And more particularly, to a device and a method for diagnosing a sleeping breath disorder using a time display device.

In general, sleep disorders are disorders in which a person can not take a healthy sleep, takes a sufficient amount of time to sleep, but does not maintain a state of alertness during daytime activity, or has a disordered sleep rhythm.

Sleep disturbances can be caused by a variety of causes, but sleep disordered breathing disorders are common. Examples of sleeping breathing disorders include snoring and sleep apnea. The sleep apnea is a disease characterized by repetitive obstruction of the upper airway during sleep, which lowers nighttime sleep efficiency, hinders deep sleep, and lowers blood oxygen saturation.

Studies have shown that these sleeping breathing disorders are closely related to the occurrence of obesity, hypertension, diabetes, dementia, cardiovascular disease, heart failure, sexual dysfunction, cerebrovascular disease, stroke and metabolic syndrome, Various techniques for diagnosing and treating respiratory disorders have been developed.

As a conventional technique for diagnosing sleeping breathing disorder, there is a registered patent No. 10-0458421 (registered on Nov. 15, 2004, an image processing apparatus and method for sleeping breathing disorder diagnosis).

In the registered patent, the diagram image obtained by drawing the shape of the oral pharyngeal region corresponding to each moment from the multi-level sectional images obtained at each moment as a result of the oral pharyngeal examination by electron beam tomography is derived, And to analyze the change of the oral pharynx and the location of stenosis and occlusion more precisely.

However, since the above-mentioned patent can obtain a diagram image through a multi-level sectional image, the diagram image itself is also a two-dimensional image, so that it is difficult to accurately grasp the position and degree of the stenosis.

This is due to the limitations of the 2D image. In the case of occlusion occurring in the anterior and posterior sides, occlusion may not be found when the two-dimensional section is taken from the front. Similarly, occlusion in the left and right direction This is because the degree and position of occlusion may not be accurately displayed in 2D images taken from the side.

In addition, conventional 2D sectional images and diagram images can be displayed to obtain diagnosis results that can be understood at the expert level. It is difficult to understand from the viewpoint of the patient who does not have expert knowledge, and subjective judgment of experts is intervened Therefore, there is a problem that reliability may be deteriorated because there may be a difference in judgment among experts even if the same image is placed.

As is known, a photographing apparatus for photographing a cross-sectional image uses radiation, so that a photographer other than a patient (or a photographer) or a photographer operates the tomography apparatus in a place isolated from the tomography apparatus.

At this time, since there is no way to confirm whether the patient is in the sleep state or in the sleep state, it is very difficult to capture the shooting time. However, since it is not possible to accurately determine whether the patient is in the state of breathing abnormality, the patient may be repeatedly attempted tomography several times, Which is a problem in that it is exposed more.

SUMMARY OF THE INVENTION The present invention has been made in view of the above problems, and it is an object of the present invention to provide a display device capable of accurately detecting a respiratory anomaly during a sleeping of a patient and displaying a tomographic imaging time point.

In addition, the present invention reproduces the three-dimensional structure of the airway using a two-dimensional sectional image and reproduces the movement of the three-dimensional structure with the passage of time, thereby realizing a more accurate detection of the degree, A display device, a time display device, and a method for diagnosing a sleeping breathing disorder.

The present invention also relates to a photographing time display device, a sleeping breathing trouble diagnosis device and a method using the time display device, which can improve the visibility of position and degree of occurrence of stenosis and closure by comparing three- .

The present invention also provides an apparatus and method for diagnosing sleep-disordered breathing using a point-of-view display apparatus and a point-and-click display apparatus capable of obtaining accurate information on the position and degree of obstruction and obstruction through various graph analysis .

Another object of the present invention is to provide an apparatus and method for diagnosing a sleeping breath disorder using a pointing device capable of enlarging a part of a displayed graph and displaying data in a specific section in detail.

In order to solve the above problems, an imaging time display apparatus according to the present invention includes an electromyogram detection unit for detecting an electromyogram of a subject, an oxygen saturation detection unit for detecting an oxygen saturation of the subject, a breathing state detection unit for detecting a respiration state of the examinee, A signal conversion unit for converting the detection results of the electromyogram detection unit, the oxygen saturation degree detection unit, and the breathing state detection unit into a digital signal; and an arithmetic processing unit for receiving the electromyogram, oxygen saturation, An arithmetic processing unit for calculating an exponent, and a display unit for displaying the apnea index calculated by the arithmetic processing unit and indicating that photographing is possible.

According to an embodiment of the present invention, the arithmetic processing unit may weight the electromyogram, the oxygen saturation, and the respiration state, respectively, so that the apnea index can be determined by the breathing state element.

According to an embodiment of the present invention, each of the EMG and the oxygen saturation may be used to check whether the respiratory state element is erroneous, without giving weight to the determination of the apnea index.

According to an embodiment of the present invention, the arithmetic processing unit calculates apnea index using the following equation (1).

According to an embodiment of the present invention, the weighting factors i, j and k are settable values, i is 0.5 to 0.8 (50 to 80% weighted), j is 0.1 to 0.3 (10 to 30% Weight), and k = 0.1 to 0.2 (10 to 20% weighted).

According to an embodiment of the present invention, the display unit includes an exponential display unit for displaying the apnea index numerically, a graphical display unit 62 for displaying the degree of apnea index in a graph, ).

The apparatus for diagnosing a sleeping breath disorder using the viewpoint display apparatus according to one aspect of the present invention includes a two-dimensional image processing unit 100 for processing a cross-sectional image of an oral pharyngeal region photographed through the image capturing means 110; A three-dimensional image processing unit 300 for forming a three-dimensional model of the oral pharynx using the image processed by the two-dimensional image processing unit 100; An animation processing unit 400 for shaping the movement of the oral pharynx using the three-dimensional image of the three-dimensional image processing unit 300; A graph processor 500 for providing a graph indicating the constriction and the closed interval of the oral pharynx using the minimum area, the maximum area, and the average area of the oral pharynx; A wearable device 600 that is usually worn by the examinee to provide normal sleep time and water level data; A control unit 700 for receiving the sleeping time and sleeping degree data of the wearable device 600 through the communication unit 710 and determining the reliability of the inspection; An electromyogram detecting unit, an oxygen saturation detecting unit, a breathing state detecting unit, a signal converting unit for converting detection results of the electromyogram detecting unit, the oxygen saturation detecting unit, and the breathing state detecting unit into digital signals, An arithmetic processing unit which receives the electromyogram, the oxygen saturation and the respiration state signal converted into the digital signal by the signal converting unit and calculates the apnea index by calculating the apnea index and the apnea index calculated by the arithmetic processing unit, And an external interface unit 900 for receiving the EMG, oxygen saturation, and breathing state at the time of photographing from the photographing time display apparatus having a display unit for displaying in color, and providing the received EMG, oxygen saturation, and breathing state to the control unit 700.

According to an embodiment of the present invention, the graph processor 500 obtains a percentage of a difference between a maximum area and a minimum area with respect to a maximum area of the oral pharynx, and displays the percentage of difference between the maximum area and the minimum area at each position of the three- The exact location and extent of the stenosis is indicated by determining the area of the awakening state and the minimum area of the oral pharyngeal position in the sleeping state so that the occurrence of the snoring can be confirmed and the total airway area of the three- The average airway area is divided by the scan time, and the stage of the sleeping person's sleep disorder can be confirmed.

The method for diagnosing a sleeping breathing disorder using the viewpoint display apparatus according to another aspect of the present invention includes the steps of: a) extracting a two-dimensional cross-sectional image of the oral pharyngeal region photographed through the image capturing means 110, ; b) forming a three-dimensional model of the oral pharynx by laminating the oral pharyngeal two-dimensional images on a position-by-position basis and rendering an interval therebetween; c) arranging the three-dimensional models of the oral pharynx in chronological order, and interpolating and animating the three-dimensional models; d) The percentage of the difference between the maximum area and the minimum area for the maximum area of the three-dimensional model of the oral pharynx is obtained and displayed for each position of the three-dimensional model of the oral pharynx to determine whether or not the snoring has occurred Or displays the minimum area of each position of the three-dimensional model of the oral cavity in the awakening state and the sleeping state to indicate the exact position and degree of occurrence of stenosis or occlusion, Dividing the average airway area by the scan time to obtain the average airway area so that the step of the sleeping person's sleeping disorder can be confirmed; e) confirming the electromyogram, oxygen saturation and breathing state of the photographed image of the photographed image by inputting the electromyogram, oxygen saturation, and respiration state of the examinee for determining the photographing time using the image photographing means 110; .

According to the embodiment of the present invention, the normal sleeping time and sleeping degree data of the examinee can be received from the wearable device worn by the examinee, and the reliability of the diagnosis result can be evaluated.

The photographing time point display apparatus according to the present invention detects the electromyogram and the oxygen saturation in the sleep state of the patient to measure whether or not the breathing abnormality is in the sleep state and displays the measurement result so that the photographer at another isolated position can easily confirm it, So that the radiation exposure of the patient can be minimized.

In addition, an apparatus and method for diagnosing a sleeping breath disorder using the time display apparatus of the present invention can reproduce a three-dimensional structure of airway using a two-dimensional sectional image and reproduce the movement of a three- Accurate detection of the degree, position, and timing of the subject can be performed, thereby enabling accurate diagnosis.

In addition, the present invention can improve visibility by mapping color according to the position and degree of stenosis and obstruction by comparing the three-dimensional structure at the time of awakening and sleep, thereby providing a diagnostic result that can be easily understood even from the standpoint of a non-specialist There is an effect.

In addition, the present invention can obtain accurate information on the position and degree of stenosis and obstruction through various graph analysis, and it is possible to perform an objective diagnosis without subjective judgment intervention of an expert.

Further, the present invention can enlarge and display a part of the graph by selecting a part of the graph, thereby enabling more accurate data analysis.

1 is a configuration diagram of a photographing time display apparatus according to a preferred embodiment of the present invention.

FIG. 2 is a waveform diagram showing an example of an airflow waveform detected by the breathing state detecting unit 30. FIG.

3 is a waveform diagram showing an example of the carbon dioxide concentration waveform detected by the breathing state detecting unit 30. As shown in FIG.

Fig. 4 is a configuration diagram of one embodiment of the display unit 60. Fig.

5 is a block diagram of a sleeping breathing disorder diagnosis apparatus according to a preferred embodiment of the present invention.

6 is an example of a screen of the display unit 800 in a state where a region of interest is detected in a two-dimensional sectional image.

FIG. 7 is an example of a screen of the display unit 800 that displays the completed three-dimensional model of the oral pharyngeal.

FIG. 8 is a result of mapping a color to a three-dimensional modeling result in the volume rendering module 310 using the color mapping module 320 of the 3D image processing unit 300.

9 to 12 are examples of a test result graph processed in the graph processor 500, respectively.

- Explanation of symbols -

10: EMG detector 20: Oxygen saturation detector

30: breathing state detecting unit 40: signal converting unit

50: operation processing unit 60:

100: two-dimensional image processing unit 110:

120: ROI extraction module 200:

300: three-dimensional image processing unit 310: volume rendering module

320: Color mapping module 400: Animation processing part

500: Graph processor 600: Wearable device

700: control unit 710: communication unit

800: Display unit 900: External interface unit

The apparatus and method for diagnosing a sleeping breathing trouble using the time display apparatus and the time display apparatus according to the present invention will be described in detail with reference to the accompanying drawings.

The embodiments of the present invention are provided to explain the present invention more fully to those skilled in the art, and the embodiments described below can be modified into various other forms, The scope of the present invention is not limited to the following embodiments. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the invention to those skilled in the art.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms "a", "an," and "the" include plural forms unless the context clearly dictates otherwise. Also, " comprise " and / or " comprising " when used herein should be interpreted as specifying the presence of stated shapes, numbers, steps, operations, elements, elements, and / And does not preclude the presence or addition of one or more other features, integers, operations, elements, elements, and / or groups. As used herein, the term " and / or " includes any and all combinations of one or more of the listed items.

Although the terms first, second, etc. are used herein to describe various elements, regions and / or regions, it is to be understood that these elements, parts, regions, layers and / . These terms do not imply any particular order, top, bottom, or top row, and are used only to distinguish one member, region, or region from another member, region, or region. Thus, the first member, region or region described below may refer to a second member, region or region without departing from the teachings of the present invention.

Hereinafter, embodiments of the present invention will be described with reference to the drawings schematically showing embodiments of the present invention. In the figures, for example, variations in the shape shown may be expected, depending on manufacturing techniques and / or tolerances. Accordingly, embodiments of the present invention should not be construed as limited to any particular shape of the regions illustrated herein, including, for example, variations in shape resulting from manufacturing.

Referring to FIG. 1, a photographing time display apparatus according to a preferred embodiment of the present invention includes an electromyogram detecting unit 10 for detecting an electromyogram of a sleeping breathing obstacle examinee (patient), an oxygen saturation detecting unit 10 for detecting an oxygen saturation of a sleeping breathing obstacle examinee A respiration state detecting unit 30 for measuring the respiratory flow of the sleeping breathing obstacle examinee and a detection result of the electromyogram detecting unit 10, the oxygen saturation detecting unit 20 and the breathing state detecting unit 30, An arithmetic processing unit 50 for assigning weights to the elements of the output of the signal converting unit 40 and outputting the result of the arithmetic operation, And displays the result of the calculation in a different color according to the numerical value, thereby making it easy for the photographer at a distance to check the display.

Hereinafter, the configuration and operation of the imaging time point display apparatus according to the preferred embodiment of the present invention will be described in detail.

First, the electromyogram detecting unit 10 detects the electrical activity state of the muscles used by the sleeping patient while breathing. Normally, when the muscle is contracted or stimulated, electrical activity occurs and current is generated. In the apnea state, no current is generated because the muscle is not contracted or stimulated.

Therefore, the detection of EMG can be used as an element to confirm sleeping breathing disorder status.

Another factor that can confirm the occurrence of sleeping breathing disorders is the use of oxygen saturation in the body. Oxygen saturation refers to the ratio of the amount of hemoglobin bound to oxygen in the blood as a ratio. In the apnea state, the ratio of oxygen to bound hemoglobin is measured to determine whether the patient is in a normal breathing state or in an apnea state. The oxygen saturation detecting unit 20 can detect the breathing state by detecting the ratio of the hemoglobin combined with the oxygen.

The breathing state detector 30 directly measures the breathing state of the sleeping breathing obstacle examinee. It is possible to measure the air flow generated by respiration by separating the inspiration from the expiration by establishing the air flow sensor around the nose and mouth of the examinee and to confirm the state without respiration.

Referring to FIG. 2, the breathing state detector 30 outputs a signal of a specific waveform in a direction in which the voltage increases in the breath interval and a waveform in which the voltage decreases in the breath interval.

The section where the waveform is regularly repeated is a section in which normal breathing is performed. In the figure, as in the apnea interval (A), the section where the voltage is maintained without changing the voltage after the breath section is the breath section after the breath section is not started, Is present.

If the duration of the apnea interval A has continued for a predetermined time or more, it can be determined that the apnea is currently in the sleep state. Specifically, if the duration of the apnea interval A is 5 seconds or more, it can be determined that the apnea state is the apnea state.

The breathing state detection unit 30 further includes a sensor for detecting carbon dioxide in addition to the sensor for detecting the direction and intensity of the airflow.

Referring to FIG. 3, the concentration of carbon dioxide detected by the breathing state detecting unit 30 increases with exhalation, decreases with the concentration of carbon dioxide in the atmosphere upon inhalation, and decreases with the concentration of carbon dioxide in the atmospheric state even in the apneic interval.

In the figure, the concentration of carbon dioxide is indicated by 50 and 25, not the measured concentration, but the set value, the maximum concentration of carbon dioxide is 50, and the average value is 25.

That is, the maximum value of the concentration of carbon dioxide in the normal breathing state is set to 50, and the average value is set to 25.

In the apnea interval, the value is 3 ~ 4, which is much lower than 25.

The set value of the carbon dioxide detected by the breathing state detecting unit 30 can be understood as a value previously converted to calculate the apnea index.

The results detected by the electromyogram detector 10, the oxygen saturation detector 20, and the breathing state detector 30 are supplied to the signal converter 40 and converted into digital signals.

Then, the signals converted by the signal converting unit 40 are input to the arithmetic processing unit 50, and the arithmetic processing unit 50 outputs the result indicating the shooting time according to the respiration state in consideration of each signal.

The arithmetic processing unit 50 may be a processor including a specific algorithm and may be configured to assign weights to detection results of the electromyogram detector 10, the oxygen saturation detector 20 and the respiration state detector 30, To calculate the apnea index.

Preferably, the arithmetic processing unit 50 sets the weight of the detection result of the respiration state detection unit 30 to the highest and the weight of the detection result of the electromyogram detection unit 10 to the lowest.

This is because the respiration state detecting unit 30 measures the change in the concentration (set value) of carbon dioxide by direct breathing, and thus the detection result with high accuracy and reliability can be obtained. The detection result of the electromyogram detecting unit 10, The result can be included by the motion, and reliability can be lowered.

The algorithm used in the arithmetic processing unit 50 can be expressed by the following equation (1).

The measured carbon dioxide level (breathing level) and the normal carbon dioxide level are average values during the set time (5 seconds, etc.). In the normal case, the value is 25. As described above, If the value is low, it can be judged to be the inspiratory section or the apnea section.

If a value significantly lower than 25 lasts more than 5 seconds, it can be specified as the apnea interval.

In the above equation (1), i, j and k are values that can be set by the operator, i is 0.5 to 0.8 (50 to 80% weighted), j is 0.1 to 0.3 (10 to 30% To 0.2 (10 to 20% weighted value).

For example, assuming that the measured carbon dioxide level is 4 indicating an apnea state and the normal carbon dioxide level is 25, and when i representing a weight value of the respiratory state is 0.8, the calculation result for the breathing state element is 12.8, This value, the calculated value for the oxygen saturation factor, and the calculated value of the EMF variance element are added, and then the apnea index, which is the value obtained by subtracting 100 from the calculated value, is at least 50 or more.

This is because the value of the oxygen saturation factor or the electromyogram dispersion factor having a low weight can not be larger than that of the breathing state element having a high weight.

If, in the above example, the carbon dioxide level is 25, the calculation result for the breathing state element is 80 and the apnea index is less than 20.

Thus, the apnea index has a larger value when it is in the apnea state, and the apnea state can be confirmed by comparing the calculated apnea index with a certain reference value.

In the above example, the criterion that can be taken is based on the time when the apnea index is 50.

The oxygen saturation (SPO2) is 97% normal and less than 95% hypoxemia based on the arterial blood pressure (SaO2). Severity is less than 75%.

Considering this fact, the severe 70% is measured in Equation 1, and when the weight j is 0.1, the calculated value of the oxygen saturation factor is 0.93, which is a very small value. Such an oxygen saturation factor has a great influence on the judgment of the sleep apnea And can be used to check the reliability of the above respiratory condition elements or the malfunction of the device.

The EMG element is also a smaller value than the oxygen saturation element and can be used to check the reliability of the respiratory state element and the malfunction of the device, rather than to determine the apnea state.

The processing result of the arithmetic processing unit 50 is displayed on the display unit 60.

The display unit 60 includes an exponent display unit 61 for displaying the apnea index processed by the arithmetic processing unit 50 in numerical form and a display unit for displaying the degree of the apnea index in a graph, As shown in FIG.

As described above, the photographing time display apparatus according to the preferred embodiment of the present invention detects the breathing state, the electromyogram and the oxygen saturation of the examinee who is examined for the sleeping breathing disorder, checks whether there is an abnormality in the current breathing, It is possible to solve the conventional problem that it is difficult to confirm the respiration state of the current examinee by being located at a long distance.

Further, the data of the arithmetic processing unit 50 may be used as input data of the sleeping breathing fault diagnosis apparatus, which will be described in more detail later.

FIG. 5 is a block diagram of an apparatus for diagnosing a sleep-disordered breathing using a viewpoint display apparatus according to a preferred embodiment of the present invention.

Referring to FIG. 5, the apparatus for diagnosing a sleeping breath disorder using the viewpoint display apparatus according to the preferred embodiment of the present invention includes a two-dimensional image processing unit 100 A 3D image processor 300 for converting the image of the two-dimensional image processor 100 into a three-dimensional image, and a control unit 300 for controlling the three- An animation processing unit 400 for shaping the movement of the oral pharynx using the three-dimensional image of the mouth 300, a graph processing unit 500 for displaying a test result in a graph according to an operator input through the interface unit 200, A control unit 700 for receiving the information detected by the wearable device 600 worn by the wearer through the communication unit 710 to judge the quality of the sleeping surface and reflecting the result on the inspection result and controlling each part; Image location A display unit 800 for displaying processing results of the display unit 100, the three-dimensional image processing unit 300, the animation processing unit 400, and the graph processing unit 500; An oxygen saturation degree, and a respiration state to confirm the EMG, oxygen saturation, and respiration state at the time of photographing of the sectional image.

Hereinafter, the configuration and operation of the apparatus for diagnosing a sleeping breathing disorder according to a preferred embodiment of the present invention will be described in detail.

First, the image photographing means 110 is a means capable of photographing a section of the oral pharyngeal, such as an electron beam tomograph, a magnetic resonance photographing apparatus, etc., and can be used regardless of the specific means. The image capturing means 110 performs multi level shooting for changing the position a plurality of times and photographing a plurality of times at the same position so as to confirm the shape change of the oral ocular at each position with the passage of time Dimensional cross-sectional image can be obtained.

The two-dimensional sectional image photographed by the image photographing means 110 is stored in the two-dimensional image processing unit 100. The operator can input a control command through the interface unit 200 and display the control command on the display unit 800 .

Since the image capturing means 110 photographs a single layer, the tomographic image of the human body region including the shape of the oral cavity to be treated in the present invention is photographed, and the mouth pharyngeal region occupying only a part of the pixel region in the two- .

Therefore, the two-dimensional image processing unit 100 preferably includes a ROI extraction module 120 for extracting and extracting only the mouth pharyngeal region as a ROI.

The ROI module 120 is equipped with an algorithm for finding the mouth pharynx in a two-dimensional sectional image, and the algorithm can be applied in various ways.

For example, after an operator inputs a control command to display a two-dimensional tomographic image photographed on the display unit 800 through the interface unit 200, the image displayed on the display unit 800 is checked to display some pixels of the oral pharynx The point of interest extraction module 120 detects the pixels adjacent to the initial point and the brightness range within a predetermined initial point and brightness range to designate a region of interest and extract the region of interest.

As described above, the two-dimensional image processing unit 100 can extract only the sectional images of the oral pharyngeal used for the diagnosis of the sleep-disordered breathing using the ROI extraction module 120.

Another example of an algorithm that can be used in the ROI module 120 is to store data of various types of oral pharyngeal cross-sectional images and to set the ROI as a region of interest by searching for a shape similar to the oral pharyngeal cross-sectional image in the current cross-sectional image Can be used.

After extracting only the section image of the oral pharyngeal region as an area of interest in the two-dimensional image processing unit 100, the three-dimensional image processing unit 300 models the oral pharyngeal image as a three-dimensional image using the extracted sectional images of the oral pharyngeal region.

The three-dimensional image processing unit 300 includes a volume rendering module 310 for forming a three-dimensional model by stacking two-dimensional sectional images of the extracted oral pharyngeus, a volume rendering module 310 for forming a three- And a color mapping module 320 for mapping the color to the 3D model to increase the visibility.

The volume rendering module 310 stacks the sectional images of the oral cavity extracted from the two-dimensional image processing unit 100 in a virtual three-dimensional space according to the positions thereof, and performs volume rendering Algorithm to form a three-dimensional model of the oral pharyngeal.

The three-dimensional model of the oral pharynx is different according to the change of time (change of respiration), and therefore, the three-dimensional models of the oral pharynx are arranged in chronological order, and the shape of the oral pharynx do.

The three - dimensional model of the oral pharyngeal can be rotated to the left and right, which makes it easy to identify anterior or posterior stenosis or bilateral stenosis which can not be confirmed in a two - dimensional image.

In addition, the present invention can receive a signal of the photographing time display device that detects the EMG, oxygen saturation, and breathing state at the photographing time described above through the external interface unit 900, and can input the inputted EMG, oxygen saturation, And images can be compared to make a more accurate diagnosis.

The image taken using the image capturing means 110 is photographed when the subject is awake and in the sleep state, and the change in the shape of the oral pharynx in the awakening state and the sleep state can be easily compared through the three-dimensional model.

The color mapping module 320 operates according to an algorithm for mapping and displaying different colors according to the degree of stenosis and closure so that predetermined colors are mapped according to the degree of stenosis and occlusion.

In FIG. 8, a portion indicated by a red color (darker portion) is a portion where a lesion is suspected due to intense stenosis or obstruction.

As described above, according to the present invention, the oral pharynx is generated as a three-dimensional model, and the lesion suspicious part can be easily identified by displaying different colors according to the degree of stenosis and occlusion, and the degree can be easily confirmed.

The three-dimensional image processing unit 300 performs three-dimensional modeling and color mapping of the oral pharyngeal, and the result is processed as a moving image in the animation processing unit 400. The three-dimensional image generated by the three-dimensional image processing unit 300 is an image of the shooting moment of the image shooting unit 110, and the animation processing unit 400 arranges the three-dimensional images in chronological order.

The three-dimensional image can be animated by determining the change process of the arranged three-dimensional images as the change over the same time as the photographing time interval of the image photographing means 110.

Therefore, the present invention can more clearly confirm the difference in shape change of the oral pharyngeal during respiration in the sleeping or awake state.

Then, the graph processing unit 500 controls the position, degree, degree of treatment, and whether or not the operation is performed according to the degree and degree of stenosis and closure by the control unit 700, which receives the control command of the operator through the interface unit 200 Graphs the test results for easy identification.

The graph of the test result is displayed for each of the awakening state and the sleeping state, and various examination results can be confirmed using the maximum area, the minimum area, and the average area of the oral pharyngeal in each of the awakening state and the sleeping state.

9 is an example of a graph of a test result processed in the graph processor 500. FIG.

Referring to FIG. 9, there is a graph of a percentage of a difference between a maximum area and a minimum area with respect to a maximum area at a corresponding height.

The x-axis represents the ratio (%) value, and the y-axis represents the measurement position. Thus, a change in the difference between the maximum area and the minimum area can be known for each measurement position.

When the difference between the maximum area and the minimum area of the specific position is large, that is, when the change ratio is large, the stenosis occurs at the corresponding position in the sleeping state and the airflow narrows, It can be confirmed that the snoring occurs.

10 is another example of the inspection result graph processed in the graph processing unit 500. FIG.

Referring to FIG. 10, the graph processor 500 may display a minimum area of each position of the oral pharynx. At this time, the x axis is the area, the y axis is the position, and indicates the minimum area of the oralopharyngeal position in the awakening state and the sleeping state.

These graphs can be used to identify the exact location and extent of stenosis, and it is easy to see if it accompanies obstructive apnea. The location and extent of the stenosis can be determined to decide whether to treat or not.

11 is another example of the inspection result graph processed in the graph processing unit 500. FIG.

In the graph of FIG. 11, the total airway area at each position is divided by the scan time, which is the average airway area of the examinee.

The mean airway area is the stage of sleep disturbance of the examinee, and the smaller the average airway area, the more dangerous it is.

In the present invention, the graphs shown in Figs. 9, 10, and 11 can be displayed on the display unit 800, respectively, and can be simultaneously displayed as shown in Fig. 12 to display a comprehensive result.

In FIG. 12, VI indicates the degree of vibration, which is the resultant value in FIG. 9, and TAMA, the average airway area, which is the resultant value in FIG.

Also, the display unit 800 is configured by a touch screen method. When a specific position is displayed in a state where a graph is displayed, a graph of the corresponding position can be enlarged and displayed.

The above-described examples of the present invention are based on a two-dimensional tomographic image of a mouth pharynx taken at a hospital by a examinee visiting the hospital and performing a tomography of the oral pharynx in a state of awakening and sleeping. Because you can get narrower, you need to use your usual sleep data.

To this end, the subject wears a sleeping state wearing the wearable device 600 for several days before the examination. The wearable device 600 includes at least a sensor capable of detecting the sleeping time and the degree of the sleeping, and a communication means capable of transmitting sleeping time and degree data to the outside.

The wearable device 600 may be a smart band, a smart watch, or the like. The communication means may be an internet connection, a short-range wireless communication, or a cable, and may be connected to an external device to transmit data on sleeping time and degree.

The communication unit 710 of the control unit 700 receives the normal sleeping time and sleeping degree data of the examinee from the wearable device 600 through a possible method such as an Internet connection, a near field wireless communication, a cable connection, And the reliability of the test results described above can be determined in consideration of this.

In other words, if the difference between the degree of sleep and the degree of sleep during examination is severe, the reliability of the test result is evaluated to be low so that the test can be resumed.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit and scope of the invention will be.

The present invention enables to accurately determine the breathing state of the examinee from a distance, to know the photographing time point, to obtain the three-dimensional model of the oral pharynx of the examinee, to display the movement with time, What can be done accurately is the possibility of industrial application.

Claims

An electromyogram detection unit for detecting an electromyogram of the examinee;

An oxygen saturation detector for detecting the oxygen saturation of the examinee;

A breathing state detecting unit for detecting a breathing state of the examinee;

A signal converter for converting the detection results of the electromyogram detector, the oxygen saturation detector, and the breathing state detector into a digital signal;

An arithmetic processing unit for receiving an EMG, an oxygen saturation, and a breathing state signal converted into a digital signal by the signal converting unit and calculating an apnea index; And

And a display unit for displaying the apnea index computed by the computation processor and indicating that photographing is possible.
The method according to claim 1,

Wherein the arithmetic processing unit comprises:

Wherein a weight is set for each of the electromyogram, the oxygen saturation and the respiration state so that the apnea index is determined by the breathing state element.
3. The method of claim 2,

Wherein each of the electromyogram and the oxygen saturation is used to determine whether the respiration state element is erroneous without giving weight to the determination of the apnea index and to determine whether the respiration state element is erroneous.
The method of claim 3,

Wherein the arithmetic processing unit calculates an apnea index using the following equation (1).

[Equation 1]

i, j, k are weights
5. The method of claim 4,

In the above equation (1)

The weighting values i, j and k are settable values, i is 0.5 to 0.8 (50 to 80% weighted), j is 0.1 to 0.3 (10 to 30% weighted), k is 0.1 to 0.2 (10 to 20% Is displayed on the display unit (10).
5. The method of claim 4,

The display unit includes:

An index display unit for displaying the apnea index as a number,

And a graphical display unit (62) displaying the degree of the apnea index as a graph, and displaying the breathing state and the apnea state as colors.
A two-dimensional image processing unit (100) for processing a sectional image of the oral pharyngeal region photographed through the image capturing means (110);

A three-dimensional image processing unit 300 for forming a three-dimensional model of the oral pharynx using the image processed by the two-dimensional image processing unit 100;

An animation processing unit 400 for shaping the movement of the oral pharynx using the three-dimensional image of the three-dimensional image processing unit 300;

A graph processor 500 for providing a graph indicating the constriction and the closed interval of the oral pharynx using the minimum area, the maximum area, and the average area of the oral pharynx;

A wearable device 600 that normally wears the examinee to provide normal sleep time and water level data;

A control unit 700 for receiving the sleeping time and sleeping degree data of the wearable device 600 through the communication unit 710 and determining the reliability of the inspection; And

An electromyogram detecting unit, an oxygen saturation detecting unit, a breathing state detecting unit, a signal converting unit for converting detection results of the electromyogram detecting unit, the oxygen saturation detecting unit, and the breathing state detecting unit into digital signals, An arithmetic processing unit which receives the electromyogram, the oxygen saturation and the respiration state signal converted into the digital signal by the signal converting unit and calculates the apnea index by calculating the apnea index and the apnea index calculated by the arithmetic processing unit, And an external interface unit 900 that receives the electromyogram, oxygen saturation, and breathing state at the time of photographing from the photographing time display apparatus having the display unit having the color display unit and provides the control unit 700 with the visual information Diagnostic device for sexual breathing disorders.
8. The method of claim 7,

The graph processor 500,

The percentage of the difference between the maximum area and the minimum area with respect to the maximum area of the oral pharynx is obtained and displayed for each position of the three-dimensional model of the oral pharynx,

The minimum area of the oropharyngeal position of the awakening state and the sleeping state is determined to indicate the exact position and degree of the stenosis,

The apparatus for diagnosing a sleeping breathing disorder using a pointing device that can determine the stage of a sleeping person's sleeping disorder by dividing the total airway area of the three-dimensional model of the oral pharynx by the scan time to obtain an average airway area.
a) extracting an oral pharyngeal two-dimensional image, which is a region of interest, from a two-dimensional sectional image of the oral pharyngeal region photographed through the image capturing means 110;

b) forming a three-dimensional model of the oral pharynx by laminating the oral pharyngeal two-dimensional images on a position-by-position basis and rendering an interval therebetween;

c) arranging the three-dimensional models of the oral pharynx in chronological order, interpolating and animating the three-dimensional models of the oral pharynx;

d) The percentage of the difference between the maximum area and the minimum area for the maximum area of the three-dimensional model of the oral pharynx is obtained and displayed for each position of the three-dimensional model of the oral pharynx to determine whether or not the snoring has occurred However,

The minimum area of each position of the oral pharyngeal three-dimensional model in the awakening state and the sleep state is displayed to indicate the exact position and degree of the stenosis or obstruction,

Determining the average airway area by dividing the total airway area of the three-dimensional model of the oral pharynx by the scan time so as to identify the stage of the sleeping person's sleeping disorder; And

e) confirming the electromyogram, oxygen saturation and breathing state of the photographed image of the photographed image by inputting the electromyogram, oxygen saturation, and respiration state of the examinee for determining the photographing time using the image photographing means 110; A method for diagnosing a sleep - disordered breathing using a time - pointing device.
10. The method of claim 9,

Further comprising the step of receiving normal sleeping time and sleeping degree data of the examinee from a wearable device worn by the examinee and evaluating the reliability of the diagnosis result.