WO2019096498A1

WO2019096498A1 - Control module and oxygen supply system

Info

Publication number: WO2019096498A1
Application number: PCT/EP2018/077627
Authority: WO
Inventors: Klaus Voll
Original assignee: Ems Gmbh Emergency Medical Systems
Priority date: 2017-11-14
Filing date: 2018-10-10
Publication date: 2019-05-23
Also published as: DE202017106889U1

Abstract

A control module for an oxygen supply system (1), which is preferably portable, wherein the oxygen supply system serves for oxygen therapy in the case of elevated oxygen requirements under spontaneous breathing of a person to receive therapy and the person is only supplied with oxygen during the inhalation phase, preferably in a first part thereof, comprising a valve unit (8) with a valve inlet (8a) for receiving oxygen originating from an oxygen source and a valve outlet (8b) for supplying the person to receive therapy with oxygen, an inspiration pressure sensor (9), a control device (7), which has a first input (10a) for a first control signal that originates from the inspiration pressure sensor (9), and an electric power source (6) for supplying the oxygen supply system with power, wherein the control device (7) has a second input (10b) for a second control signal, which is based on the oxygen content in the blood of the person to receive therapy and the valve unit (8) is controlled by the control device (7) depending on the first control signal and second control signal.

Description

Control module and Sauerstoffversorqunqssvstem

The present invention relates to a control module for a preferably portable

Oxygen supply system according to the preamble of claim 1 and

an oxygen supply system according to the preamble of claim 13.

Technological background

People who suffer from lung disease often have chronic hypoxemia. The lungs are no longer able to get enough oxygen

to absorb the remaining organs continuously and in sufficient

To provide measurements with the vital element. Can the chronic be

Oxygen deficiency with medication or other treatment methods no longer fix, only helps the so-called oxygen therapy. Especially

Diseases like COPD, pulmonary emphysema, pulmonary fibrosis, cystic

Fibrosis or recurrent pulmonary embolism, make long-term oxygen therapy necessary. Such patients ("oxygen patients") are on one

dependent on a mobile oxygen system and must design both their home stay and their vacation so that the supply of oxygen is always fully covered. Especially when traveling by air, oxygen patients have to

that corresponding oxygen systems are present.

Aircraft cabins usually have a lowered cabin pressure.

Alone by the oxygen content of the cabin interior, a supply of such patients is not possible. Corresponding mobile oxygen systems are therefore

able to allow an oxygen patient longer air travel.

On the other hand, there is a need for mobile oxygen systems to be particularly space-saving, easy to handle and lightweight. In addition, the should

Oxygen consumption by the oxygen patient should be optimized as possible. In- Consequently, there are efforts to optimize the oxygen supply of an oxygen patient on the one hand and a compact as possible,

easy to handle mobile oxygen system on the other hand.

Next prior art

A control module according to the preamble of claim 1 is known from US 6,220

244 B1 known. In addition to an inspiratory pressure sensor, this well-known device includes a barometer for recording the absolute pressure. As a result, z.

B. in a reduction of the absolute pressure, for example at high altitude or in an aircraft cabin with usually lowered cabin pressure, the

The amount of oxygen to be supplied to the patient should be adjusted accordingly.

However, people often respond to altitude or reduced cabin pressure

individually very different, which is particularly different from the person to person different blood flow to the vessels, the general condition of the person

etc. depends.

DE 10 2007 042 153 A1 discloses a device for the mobile emergency care of a patient suffering from carbon monoxide poisoning. For carbon monoxide

Poisoning will be an immediate longer-term as standard therapy

as intensive as possible ventilation of the patient with increased oxygen concentration made. The device essentially comprises an oxygen cylinder, a pressure reducer, a ventilator, a measuring device for detection

the carbon monoxide in the blood and an applicator in the form of a mask or

a tube. Depending on the detected carbon monoxide in the blood, the

Increased dose of oxygen supplied. In this known device, however, there is no control of ventilation but only an additive

Addition of oxygen to enrich for the degradation of carbon monoxide, the oxygen content in the blood of the patient. Consequently, this device does not include

Inspiration demand valve for controlling spontaneous breathing. Aufqabe the present invention

The object of the present invention is a generic

Control module for a preferably portable oxygen supply system and to provide a corresponding oxygen supply system, with

An improved oxygen supply can be achieved.

Solution of the task

The object is achieved by a control module according to the features of the claim

1 or by an oxygen supply system according to the features of the claim. Advantageous embodiments of the present invention are

claimed in the subclaims.

In that, according to the novel control module, the oxygen content, preferably the oxygen saturation value,

In the blood of the person to be treated constantly monitored and as additional

Control variable is used to supply the patient with oxygen during his inhalation phase, in contrast to the prior art, the "individual oxygen situation" of the patient permanently be used as the basis of oxygenation. The idea enables a so-called "closed

Loop system "in relation to the supply of oxygen during spontaneous breathing of the patient to realize. Indirect measurements, e.g. the measurement

of absolute pressure, and the associated uncertainties

can therefore be omitted. Due to the control module according to the invention that is

Oxygen supply system capable of responding to individual patient conditions,

e.g. Patients with blood vessel disease, patients taking medication

stand, etc., to respond. As a result, the safety of the patient in pressurized aircrafts of aircraft during flights is significantly increased. The control module also allows long-term, targeted, oxygen therapies

make. The first and second inputs of the control device may be

two physically separate inputs, with separate ones

Signal supply lines are connected. Alternatively, the first and second

Input also be realized in the form of two logic inputs of the control device. Physically, this is a single input, the received signal in this case being further processed by an effective logic circuit or assignment, for example by means of a special addressing.

According to an expedient embodiment, the respiratory rate of the to be treated

Person, preferably via the inspiratory pressure sensor, in addition

determined and included as the third control signal in the control of the valve unit.

Conveniently, the second control signal is used to control the so-called oxygen bolus (i.e., the amount of oxygen per unit of time) during spontaneous breathing, i. to vary. Accordingly, the amount of oxygen can thus be adjusted during a unit of time as a function of the measured value of the oxygen saturation in the blood of the patient.

Preferably, based on the second control signal, the duration of the oxygen inspiratory flow during the inspiratory phase of an inspiratory period

be changed during spontaneous breathing. In other words, that can be done in one

Respiratory cycle or during insufflation supplied amount of oxygen depending on

Need to be increased or decreased.

Since the oxygen inspiratory flow only covers a portion of the insufflation per unit of time, an oxygen inspiration basic flow is predefined within this subarea and, based on the oxygen inspiration basal flow, the duration of the oxygen inspiratory flow on the basis

of the second control signal is raised and / or lowered, is an optimal

Effectiveness with regard to the individual oxygen consumption almost without

dead space

reached. This achieves optimum oxygen utilization, without consuming oxygen unused. This results in the

Advantage that the oxygen supply system can be designed to be particularly compact.

It is advantageous if the portion of the insufflation covered by the oxygen inspiratory flow per unit of time is only a maximum of 35%, preferably at least a maximum of 30%, particularly preferably at least a maximum of 25%.

the total area of insufflation.

Furthermore, it is expedient for regulation or for controlling the valve unit to specify an oxygen content desired value, which is valid by the

Adjust control measures and the consequent increased addition of oxygen.

Preferably, the oxygen content setpoint is at least 90%.

The second control signal is preferably from a non-invasively operating oxygen sensor, which is arranged on the patient side. Preferably, the sensor is a so-called pulse oximeter, which, for example, on a

Finger or the like attacks. Hereby can the

Alternatively, a transcutaneous or subcutaneous oxygen sensor may be used to generate the second control signal. With such oxygen sensors not only the saturation value but the exact oxygen content in the blood can be determined. This in turn has the advantage that useful patient data can be generated at the same time.

Depending on the application, the transmission of the second control signal of

the oxygen sensor to the control device via a, preferably electrical,

Signal line done.

Alternatively, there is the possibility that the control module may be a radio receiver, preferably for near range radio, e.g. Bluetooth or the like.

The present invention further relates to an oxygen supply system, preferably in a portable embodiment, according to the preamble of claim 15. To achieve the above object, the oxygen supply system comprises

a control module according to any one of claims 1-14. The

Oxygen supply system according to the invention is thereby able to

To perform a very accurate, patient-individualized oxygenation, on the other hand, due to the optimal oxygen utilization, without

additional oxygen is consumed without effect, the dimensions of the

To reduce oxygen supply system.

Furthermore, the non-invasively operating sensor, e.g. the pulse oximeter, be equipped with a radio transmitter. In concrete terms, this may be a radio transmission part for the so-called near-field radio range, such as e.g. Bluetooth, act.

It is particularly expedient if such an oxygen cylinder is used, which contains a filling with a minimum pressure of 300 bar.

Furthermore, a (further) pressure regulator can be provided, preferably on or in the region of the control module, with which the pressure and flow can be adjusted as needed by the patient.

As a source of oxygen is a handportable oxygen cylinder with gaseous oxygen and / or a handportable thermo container with liquid oxygen is provided.

Description of the invention with reference to embodiments

Following are expedient embodiments of the present invention

explained in more detail with reference to drawings. Show it:

1 shows a first embodiment of the oxygen supply system according to the invention in a highly simplified, schematic representation;

2 shows a further embodiment of the oxygen supply system according to the invention in a greatly simplified, schematic representation;

Fig. 3 is a highly simplified schematic representation of an Atemperiode

when using the control module according to the invention; FIG. 4 shows a comparison of the course of the measured SP02 value, the measured DR value and the respectively adjusting oxygen flow as well as FIG

Fig. 5 shows a further embodiment of the oxygen supply system according to the invention in a highly simplified, schematic representation.

Reference numeral 1 in Fig. 1 denotes an oxygen supply system according to the present invention in its entirety. This is a

Oxygen supply system

for the oxygenation of persons, in particular

suffer from chronic oxygen deficiency (hypoxemia). The oxygen supply system

1 is mobile or portable, i. it can be in a bag or

be carried or carried by the person concerned.

Likewise, it is suitable to be used for the so-called homecare area too

become. The oxygen supply system 1 comprises a self-sufficient oxygen source, in particular in the form of an oxygen cylinder 3, in which oxygen is stored under high pressure (> 300 bar). The oxygen cylinder 3

of the oxygen supply system 1 according to the invention is preferably

made of carbon. The oxygen is medical oxygen

from 100% or within a range of 100% to 95%. Alternatively, oxygen may be supplied from a mobile thermal tank 20 with liquid oxygen having a valve 21.

The oxygen supply system 1 further comprises, as a functional unit, a control module 2, which is provided to control the oxygen inspiration flow towards the person to be treated, wherein the person to be treated

Person breathing spontaneously at the same time. In other words, the control module 2 controls an increased supply of oxygen in addition to the remainder of respiratory gas that may be inhaled by the person from the environment. The control module

2 may preferably be carried in a bag (not shown) or the like by the person to be treated (even on the body).

The control module 2 comprises a control device 7, e.g. in form of

Processor, microcontroller or the like. Furthermore, the operation of the

control module

an electric power source 6 in the form of a rechargeable battery

or a battery. The control module 2 can also have a display 15 and / or via an input device 16 in the form of buttons, touch screen or the like.

Reference numeral 8 denotes a valve unit having a valve inlet 8a as well

a valve outlet 8b. The valve inlet 8a is connected via a, preferably flanged, miniature pressure regulator 4a with the oxygen cylinder 3 via an oxygen feed line 13 or with the mobile thermal container 20 via an oxygen feed line 22 in connection. The other end of the oxygen feed line

13 communicates with a pressure regulator 4 on the oxygen cylinder 3 in connection.

The pressure regulator 4 reduces the pressure of the oxygen from the tank pressure

(e.g., 300 bar) to a reduced pressure (e.g., 5 bar) at the outlet of the

Pressure regulator 4. The oxygen cylinder 3 has in the head region thereof a valve with a handwheel for opening and closing the oxygen cylinder 3. The

Pressure regulator 4 also includes a valve to be operated with a handwheel

for opening and closing the pressure regulator 4 and also an indicator

of pressure and / or oxygen flow (e.g., 9 liters / minute). If the control module 2 on the

Oxygen feed line 22 connected to the thermal container 20, the patient may alternatively be supplied with oxygen from a liquid oxygen source.

At the valve inlet 8a of the valve 8 is open with the bottle-side pressure regulator 4, open

Bottle valve and open control module side pressure regulator 4a oxygen at a pressure of e.g. 1 bar on and

conditionally (at flow) an oxygen flow of e.g. 9 liters per minute.

The valve outlet 8b is connected via an oxygen supply line 19 with a

Application device, e.g. a nasal cannula 14, connected.

The control device 7 of the control module 2 comprises a first input

10 a, which is connected to the inspiratory pressure sensor 9. The inspiratory pressure sensor 9 detects pressure changes and generates on the basis of the detected

Pressure changes a first control signal, which the control device. 7

is led to the first input 10a. That is why the

Inspiratory pressure sensor 9 incorporated into the flow connection of the nasal cannula 14 and the valve 8 to a justified by the start of the inspiration pressure change

to detect. As a result, the first control signal is generated and the

Control device 7 is supplied, whereupon the latter switches the valve 8 to passage DL, so that oxygen leaves the oxygen cylinder 3 via the oxygen feed line 13, the valve 8 via the valve outlet 8b and on the Oxygen supply 19 and nasal cannula 14 the person to be treated with

Supplied oxygen. After a predetermined time, preferably before

When the inspiration ends, the control device 7 switches the valve

8 to Non-Pass NDL so that the patient's oxygen supply is interrupted. This process is repeated for each Atemperiode continuously.

In this way, the person to be treated is supplied with oxygen as part of their spontaneous breathing over a starting region of inspiration, whereby

the oxygen requirement of the person over a longer period can be covered. First, the controller may switch the valve ON / OFF.

According to the invention, the control device 7 comprises a second input

10b for a second control signal which is at the oxygen saturation value

(SP02) in the blood of the person to be treated. For this purpose, a preferably non-invasively operating sensor, in particular a so-called pulse oximeter 5, is applied to the person, whereby the oxygen saturation content in the blood of the person detected and the control device 7 via the second input

10b can be supplied.

In the example shown in FIG. 1, the pulse oximeter 5 is located at the index finger of the person to be treated, whereby the determination of the oxygen saturation in the blood (artery) is based on the measurement of the light absorption or light remission

when the skin is examined. For connection, in the embodiment shown in FIG. 1, an electrical signal line 1 1 is used.

According to the further embodiment shown in FIG. 2, between the control module 2 and the pulse oximeter 5, a radio link 12, preferably

a near range radio link such as e.g. Bluetooth or the like may be provided. In this case, the control module 2 has a radio receiving part

17, which with the second input 10 b of the control device. 7

communicated. Accordingly, the pulse oximeter 5 has a radio transmission part

18th The first and second inputs 10a, 10b of the control device 7 may be two physically separate inputs, which are in communication with two separate signal supply lines. Alternatively, the first and second input 10a, 10b in the form of two logical inputs of

Control device 7 be realized, in which case only a logical

Circuit or assignment, for example, by a special addressing, must be done.

The mode of operation of the control module will be explained in more detail below with reference to FIG. 3. FIG. 3 shows, in a highly simplified, schematic representation, a single respiratory period, which is approximately comparable to a sinusoidal oscillation. The period of respiration is divided into the field of inspiration as well

the area of expiration. In the context of inspiration, the so-called

Oxygen insufflation takes place, i. filling and puffing up of lung cavities

(Alveoli).

According to the invention, only within a partial area TB of the insufflation in the context of the control of the oxygen supply system 1 oxygen

fed. This subarea TB is about 20% of the inspiration. This results in that a large part of the supplied oxygen can be applied effectively, without increasing a so-called dead space ventilation. This area is shown in dotted lines in FIG. This will be done with the help of the new control module

Range now depending on the situation within a given range

DTB displaced either to the right or to the left in FIG. 3. To the right in FIG. 3 means that oxygen is supplied more frequently in each respiratory period than in the normal case (TB). This can increase the

Oxygen demand of the patient are compensated. Likewise, it is also possible for the control module 2 to return the partial area TB of the supply of oxygen to a range <TB, for example when the person to be treated sleeps. In this way, on the one hand, depending on the situation, an increased one

Supplied oxygen or reduced oxygen supply fraction, if just a smaller proportion is needed. This results in a very effective

Use of oxygen over the unit of time, which in turn causes the - ll -

Oxygen supply system 1 according to the invention particularly lightweight, compact

and can be made handy.

The illustration according to FIG. 4 shows the "closed-loop" control of the oxygen supply by the control module 2 according to the invention in the time sequence.

According to the upper diagram, a setpoint for the oxygen saturation in the blood of z. 94%, e.g. the oxygen saturation in the blood

the patient should not fall below the setpoint of z. B. 94% fall. The

upper curve shows schematically the detected by the pulse oximeter 5 and the

Control device 7 of the control module 2 supplied oxygen saturation in

Blood of the person to be treated.

The graph below shows the course of the pressure difference DR, which is detected by the inspiratory pressure sensor 9. At the beginning of each breath, the inspiratory pressure sensor 9 detects a negative pressure difference resulting from the beginning of the inhalation process, whereupon the control means

7 the valve 8 switches to passage DL, whereby an oxygen

Flow of e.g. 9.0 liters / minute (see picture below). After a predetermined

Time, the oxygen flow of control module 2 is turned off. How out

Fig. 4 is clearly visible, in the event that the system decreases the

Oxygen concentration in the blood, the time during which the oxygen

Flow is active, increased. As a result, more oxygen is supplied to the patient in the context of spontaneous breathing. As soon as the oxygen concentration has returned to the specified setpoint of 94%, the duration of the oxygen flow is reduced back to the starting time range.

The oxygen supply system according to the invention is therefore a so-called "closed-loop" method, which makes it possible to use the

Regulate oxygen supply person-specific situation-dependent, without it falls below the specified setpoint of 94%. Even a situation

in which the individual, to be cared for, for example, due to a

individual sudden onset of illness or weakness, a reduced one

Experience oxygen saturation concentration in the blood, the inventive

Oxygen supply system react and this person increased oxygen respectively.

In the further embodiment according to FIG. 5, instead of a pulse oximeter 5, a transcutaneous oxygen sensor 5a is used which is located on the skin of the patient and detects the actual oxygen content in the blood of the patient through the skin of the patient. Instead of the transcutaneous oxygen sensor 5a, it is also possible to use a subcutaneous oxygen sensor 5b, which is housed under the skin of the patient and also detects the actual oxygen content in the blood of the patient. Both options are shown in Fig. 5 alternatively. The signal transmission takes place via the signal line. The signal transmission can also take place in the way shown in Fig. 2. The further features of the embodiment according to FIG. 5 correspond to those of the embodiments according to FIGS. 1 and 2. For the control according to FIGS. 3 and 4 applies

appropriate.

The invention therefore makes a very special contribution to the relevant

Field of technology.

REFERENCE LIST Oxygen supply system

control module

Oxygen cylinder with gaseous oxygen

pressure regulator

a mini pressure regulator

Pulse oximeter

a transcutaneous oxygen sensor

b subcutaneous oxygen sensor

energy

control device

Valve

a valve inlet

b Valve outlet

Inspiration pressure sensor

0a first input to the controller

0b second input to the control device 1 signal line

2 radio connection

3 oxygen feed line with gaseous oxygen4 nasal cannula

5 display

6 input device

7 radio receiving part to control device

8 radio transmission part to pulse oximeter

9 oxygen supply line

0 Mobile thermo container with liquid oxygen

1 valve for removing liquid oxygen

2 oxygen feed line from liquid oxygen source

Claims

1. Control module for a preferably portable oxygen supply system

(1), wherein the oxygen supply system for oxygen therapy

with increased oxygen demand under spontaneous breathing of a patient to be treated

Person serves and an oxygen supply of the person only in the

Einatemphase, preferably in a first part of the same, takes place with

a valve unit (8) having a valve inlet (8a) for receiving

oxygen derived from an oxygen source and a valve outlet

(8b) for the delivery of oxygen to the person to be treated,

an inspiratory pressure sensor (9),

a control device (7) having a first input (10a) for

a first control signal, which is provided by the inspiratory pressure sensor (9)

originates,

an electrical energy source (6) for supplying energy to the

Oxygen supply system

characterized in that

the control device (7) has a second input (10b) of a

second control signal, which is based on the oxygen content

is based in the blood of the person to be treated and

the control of the valve unit (8) by the control device (7)

in response to the first and second control signal.

2. Control module according to claim 1, characterized in that it

at the first and second inputs (10a, 10b) are two at the controller

(7) physically separate inputs provided or

two logical inputs of the control device (7) acts.

3. Control module according to claim 1 or 2, characterized in that

that determines the respiratory rate of the person to be treated and as the third tes control signal in the control of the valve unit (8) is included.

4. Control module according to at least one of the preceding claims, characterized in that on the basis of the second control signal, the oxygen bolus (amount of oxygen / time unit) during the

Spontaneous breathing is variable.

5. Control module according to at least one of the preceding claims, characterized in that on the basis of the second control signal, the duration of the oxygen inspiratory flow during the inspiratory phase of a respiratory period of spontaneous breathing is variable.

6. Control module according to at least one of the preceding claims, characterized in that

the oxygen inspiratory flow covers only a portion of the insufflation per unit of time,

within this subarea an oxygen-inspiratory groundflow

is given and

starting from the oxygen-inspiratory basic flow, the duration of the oxygen-inspiratory flow can be raised and / or lowered on the basis of the second control signal.

7. Control module according to claim 6, characterized in that the

Partial area (TB) of the insufflation, which is covered by the oxygen-inspiratory flow per unit time, only a maximum of 35%, preferably a maximum of 30%, more preferably a maximum of 25% of the entire area

of inspiration or insufflation caused thereby.

8. Control module according to at least one of the preceding claims, characterized in that for regulating an oxygen content setpoint is predetermined.

9. Control module according to claim 8, characterized in that the oxygen content setpoint is at least 90%.

10. Control module according to at least one of the preceding claims, characterized in that it is the oxygen content to the oxygen saturation value.

1 1. Control module according to at least one of the preceding claims, characterized in that the second control signal from a

non-invasively operating oxygen sensor, preferably from pulse oximeter (5).

12. Control module according to at least one of the preceding claims, characterized in that the second control signal from a

a transcutaneous oxygen sensor or a subcutaneous oxygen sensor.

13. Control module according to at least one of the preceding claims, characterized in that the transmission of the second

Control signal to the control device (7) via signal line (1 1) takes place.

14. Control module according to at least one of the preceding claims, characterized in that the control module (2) has a radio receiving part (17), preferably one for the near range radio.

15. Oxygen supply system, preferably portable oxygen supply system, for oxygen therapy with increased oxygen demand under

Spontaneous breathing of a person to be treated is used and the oxygen inspiration flow is directed towards the person, with

an oxygen source,

a pressure regulator (4) mounted on the oxygen source,

a control module (2),

an oxygen feed line (13) connecting the pressure regulator to the

Control module connects,

an oxygen application device, preferably a nasal cannula

(14)

an oxygen supply line (19) connecting the control module (2) and the

Oxygen application device connects to each other, characterized

by a control module (2) according to at least one of the preceding

Claims.

16. Control module according to claim 15, characterized in that the

Oxygen sensor, a radio transmitter part (18), preferably a

Such for the Nahfunkbereich, has.

17. Control module according to claim 15 or 16, characterized

the oxygen cylinder (3) is filled with a minimum pressure of

Contains 300bar.

18. Control module according to at least one of claims 15 to 17, characterized

in that preferably a pressure regulator (4a) is provided on or in the region of the control module (2).

19. Control module according to at least one of claims 15 to 18, characterized

characterized in that an oxygen cylinder (3) with gaseous oxygen and / or a mobile thermo container (20) with liquid oxygen is provided as the oxygen source.