WO2019085155A1 - 一种高精度蠕动泵流速控制系统 - Google Patents
一种高精度蠕动泵流速控制系统 Download PDFInfo
- Publication number
- WO2019085155A1 WO2019085155A1 PCT/CN2017/115385 CN2017115385W WO2019085155A1 WO 2019085155 A1 WO2019085155 A1 WO 2019085155A1 CN 2017115385 W CN2017115385 W CN 2017115385W WO 2019085155 A1 WO2019085155 A1 WO 2019085155A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flow rate
- peristaltic pump
- pump
- blood
- control system
- Prior art date
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/06—Control using electricity
- F04B49/065—Control using electricity and making use of computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/247—Positive displacement blood pumps
- A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
- A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
- A61M60/279—Peristaltic pumps, e.g. roller pumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/06—Control using electricity
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/10—Other safety measures
- F04B49/103—Responsive to speed
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/10—Other safety measures
- F04B49/106—Responsive to pumped volume
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/20—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00 by changing the driving speed
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B2201/00—Pump parameters
- F04B2201/12—Parameters of driving or driven means
- F04B2201/1201—Rotational speed of the axis
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B2205/00—Fluid parameters
- F04B2205/09—Flow through the pump
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B2207/00—External parameters
- F04B2207/70—Warnings
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B51/00—Testing machines, pumps, or pumping installations
Definitions
- the utility model relates to the field of plasma collection, in particular to a peristaltic pump flow rate control system.
- the current anti-coagulation mechanism of the blood maintenance solution is to use calcium citrate which is combined with calcium ions in the blood to form a soluble and ionizable calcium citrate to make the free state. Calcium is converted into a bound state of calcium and loses its physiological function of coagulation, and the blood remains in a non-coagulated state.
- the proportion is proportional (usually blood: anticoagulant ratio is 16:1, the ratio is adjusted according to the individual red blood cell product HCT value), and then mixed into the anticoagulant, and then enters the centrifugal separation process.
- the red blood cells, the white film layer and the like are returned to the donor together with the previously mixed anticoagulant.
- excess blood in the maintenance fluid is returned to the patient, excess citrate may bind to calcium ions in the patient's blood, causing the patient's blood calcium concentration to decrease, posing a risk of hypocalcemia.
- the apheresis plasma equipment at home and abroad is driven by a motor-driven peristaltic pump technology.
- the rotational speed of the peristaltic pump motor is controlled by a servo motor encoder or a stepper motor + Hall sensor.
- the default peristaltic pump draws a uniform flow rate per revolution (eg 1mL/rev), and achieves anti-coagulant-to-blood mixing ratio control by the ratio of the speed of the peristaltic pump (eg, the ratio of the blood pump to the anticoagulant pump) Set to 16:1 to achieve a 16:1 ratio of blood to anticoagulant).
- the motor control technology is relatively mature. There are a series of technical means that can be used to achieve precise control of the motor speed.
- the precondition is that the flow per motor revolution is constant, but in the actual application process.
- the precondition is usually affected by the wear of the peristaltic pump roller, the individual differences of the pipeline consumables, the pipeline pressure, etc., and the flow rate extracted per revolution of the peristaltic pump has a deviation of about 20%, which leads to the actual anticoagulant. There is a deviation of about 20% in the amount used.
- the present invention provides a high-precision peristaltic pump flow rate control system.
- an embodiment of the present invention includes a motor, a peristaltic pump, a rotational speed feedback component, a flow rate feedback component, and a controller, wherein the motor is connected to a peristaltic pump, and the peristaltic pump corresponds to a connection speed.
- the feedback component and the flow rate feedback component, the rotational speed feedback component and the flow velocity feedback component are correspondingly connected to the controller, and the controller is correspondingly connected to the motor, wherein the flow velocity feedback component comprises a flow rate detecting device and a judging module.
- the flow rate detecting device is a flow sensor.
- FIG. 1 is a block diagram showing the structure of a peristaltic pump flow rate control system according to an embodiment of the present invention.
- the utility model provides a high-precision peristaltic pump flow rate control system with a flow rate feedback mechanism.
- the utility model relates to a high-precision peristaltic pump flow rate control system, which comprises a motor, a peristaltic pump, a rotational speed feedback component, a flow velocity feedback component and a controller.
- the motor is connected with a peristaltic pump
- the peristaltic pump is connected with a rotational speed feedback component and a flow rate feedback.
- the component, the speed feedback component and the flow rate feedback component are correspondingly connected to the controller, and the controller is correspondingly connected to the motor, wherein the flow rate feedback component comprises a flow rate detecting device and a determining module.
- the peristaltic pump of the utility model comprises an anticoagulant pump and a blood pump, and the anticoagulant pump is installed in the anticoagulant pipeline for driving the anticoagulant into the pipeline, and the blood pump is installed in the blood pipeline for Drive blood into the tubing.
- the coagulant pump and blood pump are common devices in the plasma collection process.
- the flow rate detecting device of the utility model detects the anticoagulant pump and the blood pump flow rate at the set rotation speed and transmits the detected anticoagulant pump and the blood pump flow rate to the judging module, and the judging module determines that the anticoagulant pump or the blood pump flow rate is less than the When the preset value is under the speed, it indicates that the roller has low pressing force and high speed feedback, which causes the flow rate of the coagulant pump or the blood pump to be too small.
- the judgment module sends the judgment result to the control device, and the control device increases the anticoagulant pump by control.
- the judgment module determines that the anticoagulant pump or the blood pump flow rate is greater than the preset value at the speed, indicating that the roller has high crushing force and low speed feedback.
- the factor causes the flow rate of the coagulant pump or the blood pump to be too large, and the judging module sends the determination result to the control device, and the control device reduces the flow rate to a preset value by controlling a correction measure for reducing the anticoagulant pump or the blood pump rotation speed.
- the flow rate detecting device of the utility model can be a flow sensor, and the flow sensor is respectively installed in the anticoagulant pump line and the blood pump line, and respectively monitors the flow rate of the coagulant pump and the blood pump.
- the accuracy of the flow sensor flow monitoring directly affects the control effect of the anticoagulant dosage.
- the flow rate sensor is provided with a self-calibration module.
- the flow rate sensor is a small-caliber high-resolution ultrasonic flow rate sensor, the flow sensor has an inner diameter range of 3-5 mm, and an outer diameter range of 6-7 mm. As an embodiment, the inner diameter is 4 mm and the outer diameter is 6.4 mm. It is a flow rate sensor of 1.25 ml/min.
- the flow rate detecting device of the present invention may further comprise a counting device and a capacity measuring device, wherein the counting device is used for counting the running speed of the anticoagulant pump and the blood pump in the set time, and the capacity measuring device is used for measuring the anti-coagulation time in the set time.
- an air detector is arranged in the anticoagulant pump line and the blood pump line, and the counting device counts the air detector in the anticoagulant pump line and the blood pump line.
- the number of operating coils of the anticoagulant pump in the interval when the corresponding pipeline has no air is detected respectively, and the anticoagulant capacity of the anticoagulant pump is calculated from the size of the anticoagulant pipeline and the length of the pipeline between the two air detectors. .
- the counting device counts the air detector in the blood pump pipeline to detect the number of running cycles of the blood pump in the blood pipeline without the air from the plasma mass reaching the set value interval, and the volume in the centrifuge cup plus air detection
- the blood volume in the blood line between the plasma bag is the blood volume through the blood pump, and the blood volume in the blood line between the air detector and the plasma bag is between the blood tube size and the air detector from the plasma bag.
- the length of the pipe is determined.
- the flow rate detecting device of the present invention may also include a counting device and a mass measuring device.
- the counting device is used for counting the running time of the anticoagulant pump and the blood pump in the set time period
- the mass measuring device is used for measuring the amount of the anticoagulant in the anticoagulant bag within the set time period and measuring the set time duration of the blood through the centrifuge The quality of the plasma obtained after centrifugation.
- the flow rate feedback component of the utility model is provided with an alarm device, and the alarm device corresponds to the connection judging module, and the flow rate feedback component can correct the range of the anti-coagulant pump and the blood pump flow rate within a preset flow rate value of ⁇ 20%, when the anticoagulant pump or When the blood pump flow rate exceeds the correctable range, it is judged that the pump control pipeline is abnormal, and the alarm device issues an alarm to notify the equipment user to check the pipeline blockage or the pump roller failure and other abnormalities in time, thereby improving the reliability and maintainability of the apheresis plasma equipment. .
- the flow rate feedback component of the utility model is externally clamped and installed in the anticoagulant pipeline and the blood pipeline, does not pollute the collected blood, and is simple to install, and can be directly applied to existing consumables.
- the advantages of the utility model are numerous. Different aspects, embodiments or implementations may yield one or more of the following advantages.
- An advantage of the utility model is that the flow rate feedback component is arranged to control the flow rate of the anticoagulant pump and the blood pump flow rate in the vicinity of the set value, thereby realizing precise control of the amount of plasma anticoagulant and improving the quality of apheresis plasma. , reducing the health impact on the donor.
- Another advantage of the utility model is that the flow rate feedback component has a modular design, which is convenient for system integration with the current single plasma collection device, and has low cost and high versatility.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Computer Hardware Design (AREA)
- External Artificial Organs (AREA)
Abstract
Description
Claims (6)
- 一种高精度蠕动泵流速控制系统,其特征在于,包括电机、蠕动泵、转速反馈组件、流速反馈组件和控制器,所述电机对应连接蠕动泵,所述蠕动泵对应连接转速反馈组件和流速反馈组件,所述转速反馈组件和流速反馈组件对应连接控制器,所述控制器对应连接电机,其中流速反馈组件包括流速检测装置和判断模块。
- 根据权利要求1所述的一种高精度蠕动泵流速控制系统,其特征在于,所述流速检测装置为流量传感器。
- 根据权利要求1所述的一种高精度蠕动泵流速控制系统,其特征在于,所述流速反馈组件设置有报警装置。
- 根据权利要求1所述的一种高精度蠕动泵流速控制系统,其特征在于,所述流速反馈组件外夹式安装于抗凝剂管路和血液管路中。
- 根据权利要求2所述的一种高精度蠕动泵流速控制系统,其特征在于,所述流速传感器设置有自校准模块。
- 根据权利要求2所述的一种高精度蠕动泵流速控制系统,其特征在于,所述流速传感器为小口径超声流速传感器,流速传感器内径范围为3-5mm,外径范围为6-7mm。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17931020.6A EP3705722A4 (en) | 2017-10-31 | 2017-12-11 | HIGH PRECISION PERISTALTIC PUMP FLOW CONTROL SYSTEM |
AU2017437743A AU2017437743A1 (en) | 2017-10-31 | 2017-12-11 | High-precision peristaltic pump flow rate control system |
RU2020117222A RU2759193C1 (ru) | 2017-10-31 | 2017-12-11 | Высокоточная система управления расходом перистальтического насоса |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721434944.5 | 2017-10-31 | ||
CN201721434944.5U CN207454227U (zh) | 2017-10-31 | 2017-10-31 | 一种高精度蠕动泵流速控制系统 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2019085155A1 true WO2019085155A1 (zh) | 2019-05-09 |
Family
ID=62253167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2017/115385 WO2019085155A1 (zh) | 2017-10-31 | 2017-12-11 | 一种高精度蠕动泵流速控制系统 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP3705722A4 (zh) |
CN (1) | CN207454227U (zh) |
AU (1) | AU2017437743A1 (zh) |
RU (1) | RU2759193C1 (zh) |
WO (1) | WO2019085155A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114002986A (zh) * | 2021-11-02 | 2022-02-01 | 保定创锐泵业有限公司 | 一种防爆型蠕动泵智能控制系统 |
US11846279B2 (en) | 2021-01-29 | 2023-12-19 | Masterflex, Llc | Accurate volume dispensing using pump and flow sensor |
US11920581B2 (en) | 2021-01-29 | 2024-03-05 | Masterflex Llc | Flow rate control for pump with flow sensor |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10716880B2 (en) * | 2018-06-15 | 2020-07-21 | Incuvate, Llc | Systems and methods for aspiration and monitoring |
CN110251144A (zh) * | 2019-07-19 | 2019-09-20 | 上海析维医疗科技有限公司 | 动物血液采集装置、采集系统及方法 |
CN110623679A (zh) * | 2019-09-20 | 2019-12-31 | 四川九八村信息科技有限公司 | 一种单采血浆机设备故障预测系统及方法 |
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EP2184492A1 (de) * | 2008-11-05 | 2010-05-12 | Roche Diagnostics GmbH | Verfahren zur Peristaltikpumpensteuerung |
CN103821706A (zh) * | 2014-02-26 | 2014-05-28 | 苏州市玄天环保科技有限公司 | 一种减速电机用于蠕动泵精确控制流量的方法 |
CN104373331A (zh) * | 2013-08-15 | 2015-02-25 | 西安大盛消防检测有限公司 | 一种消防泵水流检测控制装置 |
CN106168209A (zh) * | 2016-08-23 | 2016-11-30 | 保定雷弗流体科技有限公司 | 一种用于蠕动泵的智能流量校正方法和系统 |
CN205858633U (zh) * | 2016-07-11 | 2017-01-04 | 陕西银河消防科技装备股份有限公司 | 一种可调变量吸液泵装置 |
US20170218945A1 (en) * | 2009-12-22 | 2017-08-03 | Q-Core Medical Ltd. | Peristaltic pump with linear flow control |
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2017
- 2017-10-31 CN CN201721434944.5U patent/CN207454227U/zh active Active
- 2017-12-11 EP EP17931020.6A patent/EP3705722A4/en not_active Withdrawn
- 2017-12-11 AU AU2017437743A patent/AU2017437743A1/en not_active Abandoned
- 2017-12-11 RU RU2020117222A patent/RU2759193C1/ru active
- 2017-12-11 WO PCT/CN2017/115385 patent/WO2019085155A1/zh unknown
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EP2184492A1 (de) * | 2008-11-05 | 2010-05-12 | Roche Diagnostics GmbH | Verfahren zur Peristaltikpumpensteuerung |
US20170218945A1 (en) * | 2009-12-22 | 2017-08-03 | Q-Core Medical Ltd. | Peristaltic pump with linear flow control |
CN104373331A (zh) * | 2013-08-15 | 2015-02-25 | 西安大盛消防检测有限公司 | 一种消防泵水流检测控制装置 |
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CN205858633U (zh) * | 2016-07-11 | 2017-01-04 | 陕西银河消防科技装备股份有限公司 | 一种可调变量吸液泵装置 |
CN106168209A (zh) * | 2016-08-23 | 2016-11-30 | 保定雷弗流体科技有限公司 | 一种用于蠕动泵的智能流量校正方法和系统 |
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Title |
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See also references of EP3705722A4 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11846279B2 (en) | 2021-01-29 | 2023-12-19 | Masterflex, Llc | Accurate volume dispensing using pump and flow sensor |
US11920581B2 (en) | 2021-01-29 | 2024-03-05 | Masterflex Llc | Flow rate control for pump with flow sensor |
CN114002986A (zh) * | 2021-11-02 | 2022-02-01 | 保定创锐泵业有限公司 | 一种防爆型蠕动泵智能控制系统 |
CN114002986B (zh) * | 2021-11-02 | 2023-04-21 | 保定创锐泵业有限公司 | 一种防爆型蠕动泵智能控制系统 |
Also Published As
Publication number | Publication date |
---|---|
EP3705722A4 (en) | 2021-03-31 |
EP3705722A1 (en) | 2020-09-09 |
RU2759193C1 (ru) | 2021-11-10 |
CN207454227U (zh) | 2018-06-05 |
AU2017437743A1 (en) | 2020-05-28 |
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