WO2019037145A1

WO2019037145A1 - Catheter used for uterus

Info

Publication number: WO2019037145A1
Application number: PCT/CN2017/099586
Authority: WO
Inventors: 高峻; 宋李烟; 陈汝玲; 蔡志岗; 孔冠岳; 潘江帆; 曾峰; 李佼洋; 邱宇民
Original assignee: 广州永士达医疗科技有限责任公司
Priority date: 2017-08-25
Filing date: 2017-08-30
Publication date: 2019-02-28
Also published as: CN107582026B; CN107582026A

Abstract

Disclosed is a catheter used for the uterus, the catheter comprising a positioning protective sheath and a catheter body, wherein the positioning protective sheath comprises a positioning tube (1) and a first fixing member (2), an emergent light window (4) is provided on the positioning tube (1), the first fixing member (2) is fixedly connected to the positioning tube (1), the catheter body comprises an OCT catheter (5), and the OCT catheter (5) is provided in the positioning tube (1) and is used for transmitting emergent light to the emergent light window (4). The catheter used for the uterus has the advantage of high resolution, can solve the difficulty in the prior art of insufficient resolution when examining the endometrium to perform decision-making examination for potential lesions and tissue surfaces, and effectively overcome the problem of major operating difficulties when using conventional OCT technology for directly examining the endometrium.

Description

Catheter applied to the uterus

Technical field

The invention relates to the technical field of medical instruments, in particular to a catheter applied to a uterus.

Background technique

At present, the uterus is one of the most important organ parts of women. The health of the uterus is related to the happy life of women. Therefore, accurate and effective examination is an important guarantee for ensuring the health of women's uterus. Examination of the health status of human uterus can generally be reflected by the endometrium, and common methods of endometrial examination include endometrial biopsy, ultrasound, X-ray fluoroscopy, CT tomography, and endoscopic observation. Endometrial biopsy is a hysteroscopic scraping of the endometrium for pathological examination. It is a histological diagnosis. Its advantage is that it can be diagnosed. The disadvantage is that it is blindly taken or easily taken, especially in postmenopausal patients. Ultrasound, X-ray fluoroscopy and CT tomography all use physical pulse reflection to reconstruct images to examine the tissue. The advantages are non-invasive, painless, convenient and intuitive. The disadvantage is that when dealing with tissue surface details or initial diagnosis of cancer The resolution is not enough. Among them, the resolution of ultrasound can reach the order of 0.1mm, while the resolution of CT tomography is only up to the order of centimeters, it is difficult to find potential lesions; endoscopic observation belongs to direct imaging, the fineness of imaging Depending on the resolution of the endoscopic imaging sensor used, the resolution of the endoscope itself is limited, and the resolution is sufficient for routine examinations, but it is difficult to meet the need for potential lesions and tissue surface decision-making. For the examination of female infertility and pregnancy, detailed decision-making examination of the endometrium is required. The endometrium is covered with mucous membrane, which is composed of the mucosal epithelium and the lamina propria below it. The mucosal epithelium is columnar epithelium. In the different health states of the human body, the number and shape of the columnar epithelial cells of the mucosal epithelium are different, so the morphological features exhibited by the mucosal epithelium are also different, but the change of the characteristics is on the order of micrometers, and the conventional examination method It is difficult to give decision-making results.

Optical coherence tomography (OCT) is a high-resolution imaging technology developed rapidly in the past decade. It is based on the principle of low-coherence light interference and combined with confocal microscopy to detect different depth layers of biological tissues. For the backscattered wave echo time delay and echo intensity signal of the incident weak coherent light, the two-dimensional or three-dimensional high-resolution microstructure of the sample is obtained by scanning, so as to obtain the tomographic image of the sample to be in vivo. OCT imaging technology does not require any developer, no ionization effect and fluorescence effect, and is safer than traditional imaging technology. It is called "optical biopsy". OCT tomography imaging technology has micron-level optical resolution, X ratio. Ray and magnetic resonance imaging techniques are two orders of magnitude higher. High-resolution, non-destructive testing and other advantages make OCT tomography technology widely used in areas such as cardiovascular and have achieved satisfactory results. Direct application of OCT technology in the cardiovascular field to human endometrium is not completely applicable. There are two main reasons: First, the OCT catheter in the cardiovascular field is soft, and the overall diameter of the catheter is small, and the operation is not Convenient, so the examination of the uterine cavity is not applicable; the second is the inevitable OCT catheter close to the endometrial wall in the examination of the endometrium, which will destroy the morphological features of the endometrial mucosal epithelium , does not meet the inspection requirements. Therefore, there is an urgent need for a new type of OCT technology that can effectively solve the above problems.

Summary of the invention

In order to overcome the deficiencies of the prior art, it is an object of the present invention to provide a catheter for use in the uterus which can solve the technical problem of insufficient detection accuracy of the endometrium.

The object of the present invention is achieved by the following technical solutions:

A catheter applied to a uterus includes a positioning guard and a catheter body, the positioning guard includes a positioning tube and a first fixing member, the positioning tube is provided with an exit window, and the first fixing member and the positioning tube are fixed The catheter body includes an OCT catheter disposed within the positioning tube for acquiring image information of the endometrium through the exit window.

Further, one end of the OCT conduit is provided with a duct reflective prism for reflecting the outgoing light to the exit window.

Further, the catheter body further includes a nylon elastic tube disposed on the OCT catheter.

Further, the catheter body further includes a second fixing member, and the second fixing member is fixedly connected to the nylon elastic tube.

Further, the first fixing member and the second fixing member are both luer connectors, and one of the first fixing member and the second fixing member is a male luer connector, and the other is a female luer. Connector.

Further, the material used for the first fixing member and the second fixing member is medical plastic.

Further, the positioning tube includes an open end and a closed end, the open end is disposed at one end of the positioning tube, the closed end is disposed at the other end of the positioning tube, and the first fixing member is disposed at the open end.

Further, the shape of the exit window is elliptical.

Further, the material used for the positioning tube is medical polyethylene.

Further, the scanning mode adopted by the OCT catheter is a circumferential scanning mode.

Compared with the prior art, the beneficial effects of the present invention are:

The catheter applied to the uterus of the invention has the advantages of high resolution, and can solve the problem that the conventional technique fails to distinguish the precision of the potential lesion and the surface of the tissue when examining the endometrium, and effectively overcomes the traditional OCT technique. It is a difficult problem to apply directly to endometrial examination.

DRAWINGS

Figure 1 is a structural view of a catheter applied to the uterus of the present invention;

Figure 2 is a cross-sectional view showing the closed end of the positioning tube of the present invention.

Reference numerals: 1, positioning tube; 11, closed end; 12, open end; 2, first fixing member; 3, second fixing member; 4, exit window; 5, OCT catheter; 6, catheter reflecting prism; , nylon elastic tube.

Detailed ways

The present invention will be further described in conjunction with the accompanying drawings and specific embodiments. It should be noted that, without conflict, the embodiments described below may be arbitrarily combined to form a new embodiment. .

As shown in FIG. 1 , the embodiment provides a catheter applied to a uterus, including a positioning guard and a catheter body, the positioning guard includes a positioning tube 1 and a first fixing member 2, and the positioning tube 1 is disposed There is an exit window 4, the positioning tube 1 includes an open end 12 and an closed end 11, the open end 12 is disposed at one end of the positioning tube 1, and the closed end 11 is disposed at the other end of the positioning tube 1, and the first A fixing member 2 is disposed at the open end 12; the material used for the positioning tube 1 is medical polyethylene, and the hardness is relatively moderate. The thickness of the positioning tube 1 in the positioning guard is related to the depth of detection of the OCT conduit 5, and the thickness of the positioning tube 1 is equal to the distance between the exit beam of the OCT conduit 5 from the outside of the nylon elastic tube 7 to the position of the beam waist;

At one end of the OCT catheter 5 is provided a catheter reflecting prism 6 for reflecting the emitted light to the exit window 4 for acquiring image information of the endometrium through the exit window; During the implementation process, the reflective prism may or may not be disposed, but when the reflective prism is not provided, the OCT conduit 5 may have a bend at the exiting light, so that the effect is not so good, by providing the conduit reflecting prism 6, The transmission of light can be made more reasonable and controllable; the shape of the beam exit window 4 of the OCT conduit 5 can be either a window of any shape coaxial with the exit beam of the OCT conduit 5, or a beam exiting the OCT conduit 5. An annular window along the positioning tube 1 at the coaxial position. Preferably, the shape of the exit window 4 in the embodiment is elliptical, but it may also be any other shape such as a circle, a square, a diamond or the like. Irregular graphics, users can design according to their needs.

The first fixing member 2 is fixedly connected to the positioning tube 1. The catheter body comprises an OCT catheter 5, a nylon elastic tube 7 and a second fixing member 3. The second fixing member 3 is fixedly connected with the nylon elastic tube 7. Description The OCT conduit 5 is disposed within the positioning tube 1 for transmitting outgoing light to the exit window 4. The first fixing member 2 and the second fixing member 3 are both luer connectors, and one of the first fixing member 2 and the second fixing member 3 is a male luer connector, and the other is a female luer. Connector. The materials used for the first fixing member 2 and the second fixing member 3 are medical plastics. When the positioning guard is used with the catheter body, the OCT catheter 5 penetrates into the positioning tube 1 through the first fixing member 2, and when the OCT catheter 5 approaches the closed end 11 of the positioning tube 1, the second fixing member 3 at this time At the junction with the first fixing member 2, that is, the two medical luer connectors are arranged to cooperate with the catheter body by screwing engagement; the scanning mode of the OCT catheter 5 is a circumferential scanning mode.

The specific working principle of this embodiment:

When the endometrium needs to be image-detected, the OCT catheter is inserted into the uterus, and since the positioning tip is a medium-hardness medical polyethylene material, it does not cause any damage to the human body, and it is more convenient to locate. When the endometrial image is detected, the external image is obtained through the exit window, which makes the operation more convenient and quick.

The above embodiments are merely preferred embodiments of the present invention, and the scope of the present invention is not limited thereto, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention belong to the present invention. The scope of the claim.

Claims

A catheter for use in a uterus, comprising: a positioning guard and a catheter body, the positioning sheath comprising a positioning tube and a first fixing member, the positioning tube is provided with an exit window, the first fixing member Attached to the positioning tube, the catheter body includes an OCT catheter disposed within the positioning tube for acquiring image information of the endometrium through the exit window.
A catheter for use in a uterus according to claim 1 wherein one end of said OCT catheter is provided with a catheter reflecting prism for reflecting the exiting light to the exit window.
A catheter for use in a uterus according to claim 1, wherein said catheter body further comprises a nylon elastic tube disposed on the OCT catheter.
A catheter for use in a uterus according to claim 3, wherein said catheter body further comprises a second fixing member, said second fixing member being fixedly coupled to the nylon elastic tube.
A catheter for use in a uterus according to claim 4, wherein said first fixing member and said second fixing member are both luer connectors, and said first fixing member and said second fixing member are both The male Luer connector and the female Luer connector.
A catheter for use in a uterus according to claim 5, wherein said first fixing member and said second fixing member are made of medical plastic.
A catheter for use in a uterus according to claim 1 or 2 or 3 or 4 or 5 or 6, wherein said positioning tube comprises an open end and a closed end, said open end being disposed at one end of the positioning tube The closed end is disposed at the other end of the positioning tube, and the first fixing member is disposed at the open end.
A catheter for use in a uterus according to claim 7, wherein said exit window has an elliptical shape.
A catheter for use in a uterus according to claim 1, wherein said positioning tube is The material is medical polyethylene.
A catheter for use in a uterus according to claim 1, wherein said OCT catheter is scanned in a circumferential scanning mode.