WO2019017677A3 - 시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물 - Google Patents

시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물 Download PDF

Info

Publication number
WO2019017677A3
WO2019017677A3 PCT/KR2018/008073 KR2018008073W WO2019017677A3 WO 2019017677 A3 WO2019017677 A3 WO 2019017677A3 KR 2018008073 W KR2018008073 W KR 2018008073W WO 2019017677 A3 WO2019017677 A3 WO 2019017677A3
Authority
WO
WIPO (PCT)
Prior art keywords
muscle
citral
differentiation
regeneration
strengthening
Prior art date
Application number
PCT/KR2018/008073
Other languages
English (en)
French (fr)
Other versions
WO2019017677A9 (ko
WO2019017677A2 (ko
Inventor
박태선
Original Assignee
연세대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 연세대학교 산학협력단 filed Critical 연세대학교 산학협력단
Publication of WO2019017677A2 publication Critical patent/WO2019017677A2/ko
Publication of WO2019017677A3 publication Critical patent/WO2019017677A3/ko
Publication of WO2019017677A9 publication Critical patent/WO2019017677A9/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/316—Foods, ingredients or supplements having a functional effect on health having an effect on regeneration or building of ligaments or muscles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

본 발명은 시트랄(citrale) 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 근육 질환 예방 또는 치료용, 또는 근 기능 개선용 조성물에 관한 것으로, 상기 시트랄은 근육 세포에서 근단백질 합성 및 근육량 증가와 관련된 단백질의 발현을 증가시킬 수 있고, 근 단백질 분해에 관여하는 효소의 발현은 mRNA 수준에서부터 억제할 수 있으므로 근기능 저하, 근육 소모 또는 근육 퇴화로 인한 근육 질환에 있어서 근육 분화, 근육 재생, 근육량 증가를 통해 근력 강화 효과를 나타낼 수 있으며, 근육 감소를 억제할 수 있는 바, 근육 질환 예방 또는 치료용, 근육 분화, 근육 재생 및 근육 강화 또는 근육 양(muscle mass) 증가 또는 근육 생성 촉진 또는 근 기능 개선에 이용될 수 있다.
PCT/KR2018/008073 2017-07-18 2018-07-17 시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물 WO2019017677A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0090871 2017-07-18
KR1020170090871A KR101997335B1 (ko) 2017-07-18 2017-07-18 시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물

Publications (3)

Publication Number Publication Date
WO2019017677A2 WO2019017677A2 (ko) 2019-01-24
WO2019017677A3 true WO2019017677A3 (ko) 2019-03-07
WO2019017677A9 WO2019017677A9 (ko) 2019-04-11

Family

ID=65015182

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2018/008073 WO2019017677A2 (ko) 2017-07-18 2018-07-17 시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물

Country Status (2)

Country Link
KR (1) KR101997335B1 (ko)
WO (1) WO2019017677A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102080719B1 (ko) * 2018-07-17 2020-02-24 서울대학교산학협력단 약콩 발효물을 포함하는 근감소증의 예방, 치료용, 근력 개선 또는 근육량 증대용 조성물
WO2020017915A1 (ko) * 2018-07-19 2020-01-23 고려대학교 산학협력단 피톤치드를 함유하는 근감소증의 예방 또는 치료용 약학적 조성물
KR102666890B1 (ko) * 2023-11-28 2024-05-17 재단법인 제주테크노파크 까마귀쪽나무 추출물을 함유하는 근감소증의 예방 또는 치료용 조성물

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000044467A (ja) * 1998-07-31 2000-02-15 Lion Corp 血流促進剤
JP2009137916A (ja) * 2007-12-10 2009-06-25 Kirin Yakult Nextstage Co Ltd 肥満改善用組成物
CN103976987A (zh) * 2014-06-04 2014-08-13 古天津 一种用于治疗动脉粥状硬化的组合物
CN104762255A (zh) * 2010-06-13 2015-07-08 中国科学院生物物理研究所 由干细胞制备心肌细胞的方法和组合物及其用途
WO2017065077A1 (ja) * 2015-10-16 2017-04-20 株式会社カネカ 筋肉増強剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060105055A1 (en) * 2001-06-18 2006-05-18 Michael Marenick Arthritis and muscle soothing formulation containing whole egg powder
KR20090044719A (ko) * 2007-11-01 2009-05-07 바이오스펙트럼 주식회사 시트랄을 유효성분으로 포함하는 미백 개선용 조성물
KR101636946B1 (ko) * 2013-07-29 2016-07-06 한국생명공학연구원 오로트산을 포함하는 근력약화 관련 질환의 예방 또는 치료용 약학적 조성물
KR101691123B1 (ko) * 2014-09-26 2016-12-30 고려대학교 산학협력단 메티실린 저항성 균주에 대한 항균 조성물
CN108348565A (zh) * 2015-05-26 2018-07-31 新树有限公司 一种含有桔梗提取物的用于预防和治疗肌肉疾病或改善肌肉功能的组合物

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000044467A (ja) * 1998-07-31 2000-02-15 Lion Corp 血流促進剤
JP2009137916A (ja) * 2007-12-10 2009-06-25 Kirin Yakult Nextstage Co Ltd 肥満改善用組成物
CN104762255A (zh) * 2010-06-13 2015-07-08 中国科学院生物物理研究所 由干细胞制备心肌细胞的方法和组合物及其用途
CN103976987A (zh) * 2014-06-04 2014-08-13 古天津 一种用于治疗动脉粥状硬化的组合物
WO2017065077A1 (ja) * 2015-10-16 2017-04-20 株式会社カネカ 筋肉増強剤

Also Published As

Publication number Publication date
WO2019017677A9 (ko) 2019-04-11
KR20190009093A (ko) 2019-01-28
WO2019017677A2 (ko) 2019-01-24
KR101997335B1 (ko) 2019-07-08

Similar Documents

Publication Publication Date Title
AU2018260800B2 (en) Hepcidin analogues and uses therof
WO2012072713A3 (en) Lysine demethylase inhibitors such as cyclylcyclopropanamine derivatives for use in the treatment of diseases and disorders associated with flaviviridae
WO2018115097A9 (en) Ophthalmic composition for treatment of dry eye disease
BR112015001847A8 (pt) Composições e tratamento para doenças e distúrbios nos olhos
WO2015183963A3 (en) Therapeutic compositions including redox-active parabenzoquinones and uses thereof
MX337454B (es) Composicion acuosa que contiene bromhexina.
MY180626A (en) Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
EA201390803A1 (ru) Ингибиторы бромодомена и их применение
BR112015019794A2 (pt) composto, composição farmacêutica, agonista do receptor de esfingosina-1-fosfato, e, uso de um composto
WO2019017677A3 (ko) 시트랄을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물
EA201490377A1 (ru) Лечение рассеянного склероза комбинацией лаквинимода и глатирамера ацетата
WO2013022846A3 (en) Flavonoid compounds
BR112015015864A8 (pt) composição farmacêutica, e, uso de uma composição farmacêutica
WO2017022962A8 (ko) Ripk 억제제를 유효성분으로 포함하는 면역질환의 예방 또는 치료용 조성물
PH12017500615B1 (en) Ophthalmic composition comprising cyclosporine and trehalose
WO2015099838A3 (en) Compositions and methods of treating ocular diseases
MX2012012031A (es) Inhibidores de la actividad de la proteina tirosina quinasa y uso de los mismos para tratar transtornos oftalmicos.
MX2019001633A (es) Proteina derivada de la seda para el tratamiento de la inflamacion.
AR091724A1 (es) Tratamiento de la esclerosis multiple con una combinacion de laquinimod y fampridina, composicion farmaceutica
WO2011136573A3 (ko) 비만 치료 및 항산화 활성을 갖는 효모 가수분해물
WO2014071168A3 (en) Administering inhibitors of tgfbeta signaling to improve muscle function in cancer patients
WO2015195684A3 (en) Small molecule anti-scarring agents
EA201791525A3 (ru) Соединения для лечения блокады ремиелинизации при заболеваниях, связанных с экспрессией белка оболочки herv-w
MX2016010699A (es) Composiciones y metodos para tratar neutropenia.
WO2019017676A3 (ko) 에틸바닐린을 유효성분으로 함유하는 근력강화, 근육증강, 근육분화, 근육재생 또는 근감소증 억제효과를 갖는 조성물

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 18835756

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 18835756

Country of ref document: EP

Kind code of ref document: A2