WO2019017005A1 - High-calorie nutritional composition and package - Google Patents

High-calorie nutritional composition and package Download PDF

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Publication number
WO2019017005A1
WO2019017005A1 PCT/JP2018/011116 JP2018011116W WO2019017005A1 WO 2019017005 A1 WO2019017005 A1 WO 2019017005A1 JP 2018011116 W JP2018011116 W JP 2018011116W WO 2019017005 A1 WO2019017005 A1 WO 2019017005A1
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WIPO (PCT)
Prior art keywords
calorie
composition
nutritional composition
oil
high calorie
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PCT/JP2018/011116
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French (fr)
Japanese (ja)
Inventor
佐藤 宏樹
篤史 入倉
西谷 弘
Original Assignee
テルモ株式会社
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Priority to JP2019530870A priority Critical patent/JP7084925B2/en
Priority to CN201880049055.8A priority patent/CN110996982A/en
Publication of WO2019017005A1 publication Critical patent/WO2019017005A1/en

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/231Pectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/256Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/19Dairy proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732Pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Definitions

  • the present invention relates to a high calorie nutritional composition and package mainly for supplying nutrients by oral or gavage.
  • Patent Document 1 BACKGROUND ART
  • high-calorie nutrition composition for elderly people with decreased appetite or dysphagia, intake of a small amount of high-calorie nutrition composition can provide sufficient energy supplementation and obtain well-balanced nutrition of the three major nutrients.
  • proteins, lipids and carbohydrates as major nutrients are dispersed in a high-calorie nutritional composition with good stability without separation.
  • the object of the present invention is to provide a sufficient supply of energy by intake of a small amount, and to obtain three major nutrients in a well-balanced manner, and an excellent stability of proteins, lipids and carbohydrates as major nutrients.
  • a high-calorie nutritional composition dispersed without separation with the water, and such a high-calorie nutrition composition filled in a container, and the high-calorie nutrition composition is easily replenished without causing dripping To provide a package that can
  • a high-calorie nutritional composition comprising nutrients including protein, lipids, carbohydrates and agar,
  • a high-calorie nutritional composition characterized in that the viscosity at 25 ° C. is 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less, and the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  • the high calorie nutrient composition according to the above (1) further comprising pectin.
  • the high calorie nutrient composition according to the above (1) or (2) which has a pH of 3.0 or more and 4.0 or less.
  • a package comprising the high calorie nutritional composition according to any one of the above (1) to (8) and a container filled with the high calorie nutritional composition.
  • the high-calorie nutrition composition of the present invention energy can be sufficiently replenished even by intake of a small amount of the high-calorie nutrition composition, and the three major nutrients can be acquired in a well-balanced manner.
  • a protein, lipid and carbohydrate as major nutrients are dispersed without separation with excellent stability, and a stabilized high calorie nutrition composition is provided. it can.
  • the package of the present invention by filling the container with the high calorie nutrient composition of the present invention, miniaturization of the container, that is, the package can be realized, and the high calorie filled in the container is achieved.
  • the nutritional composition can be easily replenished by the consumer without causing dripping.
  • FIG. 1 is a perspective view showing a preferred embodiment of the package of the present invention.
  • the high calorie nutrient composition of the present invention contains a nutrient containing protein, lipid and carbohydrate, and agar, and has a viscosity of 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less at 25 ° C. And, it is characterized in that the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less. Thereby, energy can be sufficiently replenished by intake of a small amount of the high-calorie nutrition composition, and three major nutrients can be acquired in a well-balanced manner.
  • a protein, lipid and carbohydrate as major nutrients are dispersed without separation with excellent stability, and a stabilized high calorie nutrition composition is provided. it can.
  • miniaturization of the container that is, the package can be realized, and the high calorie filled in the container is achieved.
  • the nutritional composition can be easily replenished by the consumer without causing dripping.
  • the package (packing body of this invention) with which the high-calorie nutrition composition of this invention was filled in the container is demonstrated.
  • the case where the container with which the package of this invention is provided is applied to the aluminum pouch with a straw is demonstrated to an example.
  • FIG. 1 is a perspective view showing a preferred embodiment of the package of the present invention.
  • the upper side in FIG. 1 is referred to as “upper” or “upper” and the lower side as “lower” or “lower”.
  • the package 1 has a container 10 and a high-calorie nutrition composition (not shown) filled in the container 10.
  • the high-calorie nutrition composition is filled in the container 10, and as described above, according to the present invention, it contains protein, lipid and carbohydrate as nutrients (three major nutrients) and further contains agar.
  • the viscosity at 25 ° C. is 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less, and the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  • Protein is included in the high calorie nutrient composition as a nutrient (a major nutrient) for supplying a nitrogen source and an amino acid.
  • the content of the protein in the high-calorie nutrition composition is set to preferably about 10.0 g to about 30.0 g, more preferably about 12.0 g to about 16.0 g, in 100 mL of the high-calorie nutrition composition. .
  • the three major nutrients can be acquired in a well-balanced manner, and the amount of heat of the high calorie nutrient composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  • Energy can be sufficiently replenished by the intake of 100 mL, that is, the intake of the high-calorie nutritional composition filled in the package 1.
  • protein includes low molecular weight proteins irrespective of the degree of polymerization of amino acids, and includes proteins as well as amino acids and peptides as protein degradation products.
  • the protein includes collagen peptide and whey protein.
  • Whey protein is a mixture of globular proteins isolated from whey (whey) remaining when milk is coagulated, and consists of soluble components contained in milk.
  • whey protein for example, a commercially available one can be used. Specifically, WPC550 (made by Fonterra), Enlacto HG (made by Nippon Shinyaku Co., Ltd.), Entract CC (made by Nippon Shinyaku Co., Ltd.) PROGEL 800 (manufactured by Nippon Shinyaku Co., Ltd.), Lactocrystal (manufactured by Nippon Shinyaku Co., Ltd.), WPI 18855 (manufactured by Fonterra), WPI 18822 (manufactured by Fonterra), WPI 1895 (manufactured by Fonterra), WPC 392 (manufactured by Fonterra), WPC 80 (Manufactured by Fonterra), WPC 7009 (manufactured by Fonterra), WPC 164 (manufactured by Fonterra), WPC 162 (manufactured by Fonterra), WPC 132 (manufactured by Fonterra), WPC 472 (Fonterra)
  • the collagen peptide is preferably about 1,000 or more and 8,500 or less, more preferably 1,000 or more and 5,000 or less by hydrolyzing collagen derived from an animal (mainly pig, chicken and fish) with an enzyme or the like.
  • the molecular weight is reduced to the following weight average molecular weight.
  • Examples of commercially available collagen peptides include pig-derived, chicken-derived, and fish-derived collagen peptides. Specifically, porcine collagen-derived well collagen (manufactured by Nippon Shinyaku Co., Ltd.), SOLUGEL (Nippon Pure Food Co., Ltd.) GELITA SOL NPE (Nippi Co., Ltd.), GELITA SOL NPS (Nippi Co., Ltd.), Marine collagen NH derived from fish collagen (Nippon Ham Co., Ltd.) and C-LAP derived from chicken collagen (Nippon Ham Co., Ltd.) And the like.
  • the weight content of collagen peptide in the high calorie nutritional composition is 1.0
  • the weight content of collagen peptide is 1.0 or more and 26.0 or less for these collagen peptides and whey proteins. Is preferred.
  • the weight content of the collagen peptide is less than 1.0, it may be difficult to sufficiently replenish energy by ingesting a small amount of the high calorie nutrient composition.
  • the high-calorie nutritive composition has a distinctive smell, unpleasant flavor such as bitter taste, bitter taste and the like, and the ingestion of the high-calorie nutritive composition is consumed It is not possible for a person to eat deliciously, and the appetite of the user is reduced, which may lead to a decrease in quality of life (QOL).
  • QOL quality of life
  • the weight content of collagen peptide is preferably 1.0 or more and 26.0 or less when the weight content of whey protein is 1.0, but is 1.7 or more and 4.3 or less Is more preferred. Thereby, the high calorie nutritional composition can be made more stabilized.
  • the proteins may contain proteins other than collagen peptides and whey proteins, and, for example, known proteins such as animal proteins and vegetable proteins other than collagen peptides and whey proteins can be used.
  • this protein examples include proteins contained in milk etc. excluding whey protein, soybean protein and the like.
  • examples using milk as a raw material include casein, caseinate, total milk protein (TMP), milk protein concentrate (MPC), and examples using soy as a raw material include soybean protein These may be used alone or in combination of two or more.
  • TMP, MPC, soybean protein etc. can use what is marketed, and as a commercial item, MPC80 (made by Nippon Shinyaku Co., Ltd.), MPC80LR (made by Nippon Shinyaku Co., Ltd.), casein magnesium S, for example (Nippon Shinyaku Co., Ltd.), Casein potassium S (Nippon Shinyaku Co., Ltd.), Casein sodium CW (Nippon Shinyaku Co., Ltd.), Prorina 900 (Fuji Oil Co., Ltd.), Prorina 700 (Fuji Oil Co., Ltd.) , Prolina 800 (manufactured by Fuji Oil Co., Ltd.), New Fuji Pro 3000 (manufactured by Fuji Oil Co., Ltd.), New Fuji Pro 1700 N (manufactured by Fuji Oil Co., Ltd.), and the like.
  • MPC80 made by Nippon Shinyaku Co., Ltd.
  • MPC80LR made by Nippon Shinyaku Co., Ltd.
  • amino acids for example, essential amino acids such as valine, leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan, histidine and the like, and glycine, alanine, serine, cysteine, asparagine, glutamine, proline, tyrosine, aspartic acid, Non-essential amino acids such as glutamic acid and arginine can be mentioned, and one or more of these can be used in combination.
  • amino acids may be in the form of inorganic acid salts (such as hydrochlorides), organic acid salts (such as acetates), and in vivo hydrolyzable esters (such as methyl esters).
  • inorganic acid salts such as hydrochlorides
  • organic acid salts such as acetates
  • in vivo hydrolyzable esters such as methyl esters
  • peptide one obtained by polymerizing two or more of the above-mentioned amino acids via a peptide bond (amide bond) can be mentioned, and one or two or more of them can be used in combination.
  • peptide may be any of dipeptide, tripeptide, oligopeptide (about 10 amino acids) and polypeptide (several tens to hundreds of amino acids).
  • this peptide one obtained by subjecting a protein except collagen to a molecular weight reduction treatment can be used, and examples thereof include soy peptide, casein peptide, whey peptide and the like.
  • the protein, amino acid and peptide may be derived from a flavor or the like.
  • Lipids are included in the high-calorie nutrition composition as nutrients (three major nutrients) that are highly efficient energy sources.
  • the content of the lipid in the high calorie nutritional composition is set to preferably about 8.0 g or more and 30.0 g or less, more preferably about 8.8 g or more and 25.0 g or less in 100 mL of the high calorie nutrient composition .
  • the amount of heat of the high-calorie nutrition composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  • Energy that is, the intake of the high-calorie nutritional composition filled in the package 1. If the content of lipids in the high-calorie nutrition composition is less than the above lower limit value, depending on the type of lipids, the function of the skin may be reduced. If the content of lipids exceeds the upper limit, the supply of lipids becomes excessive, and depending on the type of lipids, obesity may be induced.
  • the lipid is not particularly limited as long as it can be ingested by humans, and examples thereof include saturated fatty acids, unsaturated fatty acids, vegetable oils, animal fats and oils, and the like.
  • saturated fatty acids examples include caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid and the like, and one or more of these can be used in combination.
  • unsaturated fatty acids include oleic acid, palmitoleic acid, linoleic acid, arachidonic acid, ⁇ -linolenic acid and the like, and one or more of these can be used in combination.
  • vegetable oils examples include coconut oil, corn oil, cottonseed oil, olive oil, palm oil, palm kernel oil, peanut oil, rapeseed oil, safflower oil (safflower oil), sesame oil, soybean oil, soybean oil, sunflower oil, almond oil, cashew oil , Hazelnut oil, macadamia oil, mongongo oil, pecan oil, pineseed oil, pistachio oil, walnut oil, gouto nut oil, buffalo pumpkin oil, pumpkin seed oil, watermelon seed oil, amaranth oil, apricot oil, apple oil, Argan oil, avocado oil, babassu oil, moringa oil, borneo oil, cape chestnut oil, cocoa butter, carob oil, kono palm oil, coriander seed oil, dika oil, linseed oil, grape seed oil, hemp oil, kapok real oil, Lelleman Chia oil, Marula oil, meadow foam oil, mosquito oil Chisel oil, nutmeg butter, okra oil, papa
  • animal-derived fats and oils for example, lard (pork fat), het (cow beef) and the like can be mentioned, and one or more of these can be used in combination.
  • the lipids may be used alone or in combination of two or more. Also, the lipid may be derived from a flavor or the like.
  • Carbohydrate is included in the high calorie nutrient composition as a nutrient (three major nutrients) for supplying monosaccharides.
  • the content of the carbohydrate in the high calorie nutritional composition is set to preferably about 25.0 g or more and 40.0 g or less, more preferably about 32.0 g or more and 38.0 g or less in 100 mL of the high calorie nutrient composition .
  • the amount of heat of the high-calorie nutrition composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  • Energy that is, the intake of the high-calorie nutritional composition filled in the package 1. If the content of carbohydrates in the high calorie nutritional composition is less than the above lower limit, depending on the type of carbohydrates, a sufficient amount of heat may not be obtained. When the content of carbohydrates exceeds the upper limit, the supply of carbohydrates becomes excessive, and depending on the type of carbohydrates, diabetes may be induced.
  • the carbohydrate is not particularly limited as long as it is absorbed by a living body and becomes a calorie source (energy source), and examples thereof include monosaccharides, disaccharides, and polysaccharides.
  • monosaccharides examples include glucose (glucose), fructose (fructose), galactose and the like, and one or more of these can be used in combination.
  • disaccharides examples include sucrose (sucrose), lactose (lactose), maltose (malt), isomaltose, trehalose and the like.
  • polysaccharide examples include starch (amylose, amylopectin), dextrin and the like, and one or more of them may be used in combination, and among them, dextrin is preferable.
  • Dextrin is a generic term for substances in which several ⁇ -glucoses are polymerized by glycosidic bonds, and can be obtained by hydrolyzing starch. Dextrin can prevent a rapid rise in blood glucose, because the rate of degradation in the small intestine is slow and absorption is slow. In addition, by using dextrin, the osmotic pressure of the high-calorie nutrition composition can be reduced, and osmotic diarrhea can be prevented.
  • any of high molecular weight dextrin with high degree of polymerization of ⁇ -glucose and low molecular weight dextrin with low degree of polymerization of ⁇ -glucose may be used, but high molecular weight dextrin capable of reducing the osmotic pressure can be used Is preferred.
  • the low molecular weight dextrin is also called maltodextrin, and is usually obtained by polymerizing 3 to 5 ⁇ -glucoses.
  • the dextrin may be prepared by itself or a commercially available product may be used.
  • starch contained in known starches such as corn, waxy corn, wheat, rice, waxy rice, waxy milo, beans (eg broad bean, green bean, azuki bean), potato, sweet potato, tapioca etc. It can be prepared by hydrolysis according to known methods.
  • TK-16 made by Matsutani Chemical Industry Co., Ltd.
  • Sandeck # 300 made by Sanwa Starch Industry Co., Ltd.
  • Sandeck # 250 made by Sanwa Starch Industry Co., Ltd.
  • Sandeck # 150 manufactured by Sanwa Starch Co., Ltd.
  • the above-mentioned carbohydrates may be used alone or in combination of two or more. Also, the carbohydrate may be derived from a flavor or the like.
  • low molecular weight carbohydrates having a low degree of polymerization that is, monosaccharides, disaccharides, or low molecular weight polysaccharides such as low molecular weight dextrins.
  • the compatibility of the carbohydrates in the high calorie nutritional composition becomes high, and therefore, even if the content of the carbohydrate in the high calorie nutritional composition is increased as in the above range, the high calorie nutritional composition contains It can dissolve carbohydrates together. Therefore, the occurrence of carbohydrate agglomerates and precipitates in the high calorie nutritional composition can be properly suppressed or prevented, and the high calorie nutritional composition can be one in which carbohydrates are uniformly dispersed.
  • the high-calorie nutrition composition may contain vitamins as nutrients in addition to the protein, lipid and carbohydrate nutrients (major nutrient) described above.
  • the vitamin is not particularly limited, and various types such as vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacin, pantothenic acid, vitamin B6, biotin, folic acid, vitamin B12, vitamin C, carnitine Vitamins may be mentioned, and these may be used alone or in combination of two or more.
  • preferable content of the various vitamins per 100 mL of high calorie nutrition composition is as follows.
  • Vitamin A preferably 0 to 3000 ⁇ g, more preferably 20 to 250 ⁇ g Vitamin D: preferably 0.1 to 50 ⁇ g, more preferably 0.1 to 5.0 ⁇ g Vitamin E: preferably 0.2 to 800 mg, more preferably 0.2 to 5.0 mg Vitamin K: preferably 0.5 to 1000 ⁇ g, more preferably 2 to 50 ⁇ g Vitamin B1: preferably 0.01 to 10 mg, more preferably 0.1 to 3.0 mg Vitamin B2: preferably 0.01 to 10 mg, more preferably 0.05 to 3.0 mg Niacin: preferably 0.1 to 30 mg NE, more preferably 0.5 to 6 mg NE Pantothenic acid: preferably 0.1 to 5.5 mg, more preferably 0.2 to 3.0 mg Vitamin B 6: preferably 0.01 to 6.0 mg, more preferably 0.1 to 3.0 mg Biotin: preferably 0.1 to 100 ⁇ g, more preferably 1 to 20 ⁇ g Folic acid: preferably 1 to 1000 ⁇ g, more preferably 10 to 100 ⁇ g Vitamin B12: preferably 0.01 to
  • the lower limit value and the upper limit value of the preferable range and the more preferable range of various vitamins are assumed to include the respective numerical values.
  • the high calorie nutrient composition may also contain minerals as nutrients.
  • the minerals are not particularly limited, and include, for example, various minerals such as sodium, potassium, calcium, phosphorus and magnesium, which may be used alone or in combination of two or more. .
  • preferable content of the various minerals per 100 mL of high calorie nutrient composition is as follows.
  • Sodium preferably 50 to 300 mg, more preferably 100 to 190 mg Calcium: preferably 10 to 200 mg, more preferably 30 to 100 mg Phosphorus: preferably 1 to 350 mg, more preferably 25 to 150 mg Magnesium: preferably 1 to 75 mg, more preferably 10 to 50 mg Potassium: preferably 1 to 350 mg, more preferably 25 to 180 mg
  • the lower limit value and the upper limit value of the preferable range and the more preferable range of the various minerals include their respective numerical values.
  • the high-calorie nutrition composition may contain trace elements as nutrients in addition to the aforementioned protein, lipid and carbohydrate nutrients (three major nutrients).
  • the trace elements are not particularly limited, and include, for example, various trace elements such as iron, zinc, copper, chlorine, iodine, manganese, selenium, chromium and molybdenum, which may be used alone, 2 It is also possible to use a mixture of species and more.
  • preferable content of various trace elements per 100 mL of the high calorie nutrient composition is as follows.
  • Iron preferably 0.1 to 55 mg, more preferably 1 to 10 mg Copper: preferably 0.01 to 1.0 mg, more preferably 0.06 to 0.6 mg
  • Chlorine preferably 1 to 350 mg, more preferably 25 to 180 mg
  • Iodine preferably 0.1 to 1000 ⁇ g, more preferably 1 to 100 ⁇ g
  • Manganese preferably 0.01 to 10 mg, more preferably 0.1 to 2.0 mg
  • Selenium preferably 0.1 to 450 ⁇ g, more preferably 1 to 35 ⁇ g
  • Zinc preferably 0.1 to 20 mg, more preferably 1 to 10 mg
  • Chromium preferably 0.1 to 30 ⁇ g, more preferably 1 to 20 ⁇ g
  • Molybdenum preferably 0.1 to 30 ⁇ g, more preferably 1 to 20 ⁇ g
  • the lower limit value and the upper limit value of the preferable range and the more preferable range of each of the various trace elements are assumed to include the respective numerical values.
  • the calorie content of the high-calorie nutritional composition containing the above-mentioned nutrients may be 2.5 kcal / mL or more and 4.5 kcal / mL or less, but 3.0 kcal / mL or more and 4.3 kcal / mL or less Is preferred, and more preferably 3.5 kcal / mL or more and 4.1 kcal / mL or less. If the amount of heat in the high-calorie nutrition composition is less than 2.5 kcal / mL, a small amount of high-heat can not be consumed. When the amount of heat in the high calorie nutritional composition exceeds 4.5 kcal / mL, it is difficult for the nutrients to dissolve.
  • a high-calorie nutritional composition for which elderly people with poor appetite or with dysphagia can obtain one meal under supervision of a third party such as a nurse or carer at a hospital or nursing facility etc.
  • the total amount of liquid food is generally said to be about 100 mL. Therefore, set the heat quantity of the high-calorie nutrition composition filled in 100 mL in the container 10 within the above range, and further obtain the high-calorie nutrition composition from the package 1 at breakfast, lunch and dinner three meals.
  • Energy of 750 kcal or more and 1350 kcal or less, preferably 900 kcal or more and 1290 kcal or less, more preferably 1050 kcal or more and 1230 kcal or less can be obtained. Therefore, the intake of three meals of the high-calorie nutrition composition can satisfy the amount of energy which the elderly person wants to obtain in one day.
  • the high-calorie nutrition composition may have a viscosity of 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less at 25 ° C., but 5,000 mPa ⁇ s or more and 15,000 mPa ⁇ s or less Is preferred. If the viscosity in the high calorie nutritional composition is less than the lower limit, reflux pneumonia or diarrhea may be induced. If the viscosity in the high calorie nutritional composition exceeds the above upper limit, it may become sticky at the time of intake. By setting the viscosity within the above range, the viscosity of the high calorie nutrient composition can be set within the range suitable for liquid food.
  • the high calorie nutritional composition can be easily obtained orally (eating).
  • the high-calorie nutrition composition can be easily discharged from the container body 30 by pressing of the container body 30 without causing liquid dripping through the opening 20 (supply unit) provided in the container 10 described later.
  • the user can obtain (eat) the high-calorie nutrition composition.
  • a protein, lipid and carbohydrate as major nutrients can be dispersed without separation with excellent stability, and a stabilized high calorie nutritional composition is provided.
  • a high calorie nutrient composition contains an emulsifier in addition to the nutrient containing the three major nutrients mentioned above.
  • the high-calorie nutrition composition can be one in which proteins, lipids and carbohydrates are uniformly dispersed and emulsified.
  • the emulsifier is not particularly limited.
  • organic acid monoglyceride, polyglycerin ester, sucrose fatty acid ester, sorbitan fatty acid ester, fatty acid ester such as propylene glycol fatty acid ester, polysorbate, polyglycerin condensed ricinolate, diacylglycerol, wax And sterol esters, phospholipids and the like, and one or more of these may be used in combination.
  • the content thereof is preferably 0.5 g / 100 mL or more and 1.5 g / l or more of the organic acid monoglyceride in the high calorie nutritional composition. It is set to 100 mL or less, more preferably about 1.3 g / 100 mL, and the polyglycerin ester is preferably set to 0.3 g / 100 mL or more and 0.8 g / 100 mL or less, more preferably about 0.7 g / 100 mL.
  • the above-mentioned effect can be more remarkably exhibited.
  • the organic acid monoglyceride in the high calorie nutritional composition is less than 0.5 g / 100 mL, depending on the type of nutrient contained in the high calorie nutritional composition, the emulsifying system is not stable and the water layer and the oil layer are separated. There is a risk of When the amount of organic acid monoglyceride in the high calorie nutritional composition exceeds 1.5 g / 100 mL, the emulsion system may be broken by excess organic acid monoglyceride depending on the type of nutrient contained in the high calorie nutritional composition.
  • the emulsion system may not be stabilized and the water layer and the oil layer may separate. There is.
  • the amount of organic acid monoglyceride in the high calorie nutritional composition exceeds 0.8 g / 100 mL, the emulsion system may be broken by excess organic acid monoglyceride depending on the types of nutrients contained in the high calorie nutritional composition.
  • the organic acid monoglyceride is not particularly limited.
  • a commercially available product can be used. Specifically, Poem W-60 (manufactured by Riken Vitamin Co., Ltd.), Poem G-002 (Riken Vitamin Co., Ltd.) And Poem B-10 (manufactured by Riken Vitamin Co., Ltd.).
  • the polyglycerin ester is not particularly limited and, for example, commercially available products can be used. Specifically, Poem J-0381 V (manufactured by Riken Vitamin Co., Ltd.), Poem J J 0281 V (Riken Vitamin Co., Ltd.) And the like.
  • a high-calorie nutrition composition contains fermented milk other than the nutrient which contains the three main nutrients mentioned above.
  • the high-calorie nutrition composition contains protein, lipid and carbohydrate nutrients at a high concentration as described above, and that the protein and carbohydrate nutrients are reduced as described above. Due to the fact that it is preferable, etc., it has a tendency to have unique odor, great taste, bitterness and the like.
  • the content of fermented milk in the high calorie nutrient composition is preferably set to 1.0 g / 100 mL or more and 3.0 g / 100 mL or less, more preferably 1.3 g / 100 mL or more and 1.8 g / 100 mL or less.
  • the fermented milk in the high-calorie nutrition composition is less than the above lower limit, depending on the type of nutrients contained in the high-calorie nutrition composition, bitter taste may be felt strongly and flavor may be lost.
  • sweetness and sourness may be felt strongly depending on the kind of nutrients contained in the high-calorie nutrition composition, and the flavor may be impaired.
  • fermented milk means what the thing containing the non-fat milk solid content more than milk or this equivalent produces and ferments lactic acid by microorganisms, such as lactic acid bacteria and yeast. Therefore, the fermented milk is not particularly limited as long as it is fermented from milk or one containing non-fat milk solids equal to or more than this, and is not particularly limited.
  • other than commercially available yogurt Honeypis JP-J ( Taiyo Fragrance Co., Ltd.
  • Fermented milk FM-J made by Taiyo Fragrance Co., Ltd.
  • sugar-free fermented milk base made by Kyodo Dairy Co., Ltd.
  • sweetened fermented milk solution made by Kyodo Dairy Co., Ltd.
  • the high calorie nutritional composition may contain a flavor.
  • the flavor of the high-calorie nutrition composition is further improved, and the appetite of the user who eats the high-calorie nutrition composition is further improved.
  • flavor means something added to a high calorie nutritional composition to impart a flavor or taste, and is generally sold as “flavor” or “extract”. What is marketed as “powder seasoning”, “powder flavor”, “liquid flavor” etc. are mentioned, It can be used combining 1 type, or 2 or more types in these.
  • the content of the flavor in the high-calorie nutrition composition is preferably set to about 0.1 to 3.5 g, more preferably about 0.4 to 3.0 g, in 100 mL of the high-calorie nutrition composition. Be done. Thereby, the effect obtained by adding a flavor to a high calorie nutrient composition can be exhibited more notably.
  • the type of flavor is not particularly limited.
  • vegetable soup taste such as tomato flavor
  • fruit juice taste such as apple flavor
  • yogurt flavor Japanese-style miso flavor (bonito, konbu), cream stew Flavor
  • beef stew flavor curry flavor
  • miso soup flavor pork broth flavor
  • clam chowder flavor or ramen flavor
  • ramen flavor mime, tonkotsu, soy sauce
  • the high calorie nutrient composition may further contain, as functional components, polyglutamic acid, glucosamine, fucoidan, collagen, hyaluronic acid, dietary fiber, oligosaccharides and the like.
  • These functional components have a salivary secretion promoting action, calcium absorption promoting action, moisturizing action, elimination of H. pylori bacteria, promotion of protection and repair of gastric mucosa, improvement of endurance, reduction of plasma cholesterol, improvement of blood glucose response, improvement of colon function, And various functions such as prevention of colon cancer.
  • the dietary fiber is not particularly limited, but, for example, cellulose, hemicellulose, lignin, insoluble pectin, chitin, chitosan, pylium seed coat, insoluble dietary fiber such as low molecular weight sodium alginate, water soluble pectin, guar gum, konjac mannan, glucomannan , Alginic acid, agar, chemically modified polysaccharide, polydextrose, resistant oligosaccharide, maltitol, inulin, carrageenan, wheat bran, resistant digestive dextrin (eg, pine fiber C (made by Matsutani Chemical Industry Co., Ltd.)), guar gum decomposition And water soluble dietary fiber, etc., and may be used alone or as a mixture of two or more.
  • content of the dietary fiber in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
  • the high calorie nutritional composition may further contain other known ingredients such as health functional ingredients, food additives, stabilizers and the like.
  • the health functional component is a component that exerts a certain function on a living body by ingestion.
  • Such insurance functional components include, but are not limited to, for example, nondigestible oligosaccharides, sugar alcohols, calcium citrate malate (CCM) and casein phosphopeptide (CPP), chitosan, L-arabinose, guava leaf polyphenol And wheat albumin, bean paste extract, diacylglycerol, diacylglycerol vegetable sterol, soybean isoflavone, milk basic protein and the like, and one or more of them may be used in combination.
  • resistant oligosaccharides are saccharides whose molecular weight is not as high as that of polysaccharides (about 300 to 3000).
  • the indigestible oligosaccharides are not degraded by human digestive enzymes, and those that are degraded by human digestive enzymes are included in the above-mentioned carbohydrates. By intake of such indigestible oligosaccharides, an intestinal regulation effect can be obtained.
  • indigestible oligosaccharides include, but are not limited to, xylooligosaccharides, fructooligosaccharides, soybean oligosaccharides, isomaltooligosaccharides, milk fruit oligosaccharides, lactulose, galactooligosaccharides and the like. These indigestible oligosaccharides may be used alone or in combination of two or more. In addition, content of the indigestible oligosaccharide in a high calorie nutrition composition is suitably adjusted by the subject etc. who apply a high calorie nutrition composition.
  • Sugar alcohol is a kind of sugar produced by reducing the carbonyl group of aldoses and ketoses, and is a substance that is poorly absorbed from the small intestine into the body and hardly turns into calories.
  • This sugar alcohol is difficult to be metabolized to acid by oral bacteria and can prevent the formation of dental plaque.
  • the sugar alcohol is used as a low calorie sweetener.
  • the sugar alcohol is not particularly limited, and examples include erythritol, maltitol, palatinose and the like. These sugar alcohols may be used alone or in combination of two or more.
  • content of the sugar alcohol in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
  • CCM Calcium citrate malate
  • CPP casein phosphopeptide
  • CCMs and CPPs may be used alone or in combination of two or more.
  • CCM and CPP are preferably used in combination with calcium.
  • content of CCM and CPP in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
  • the food additive is used by adding, blending, wetting or the like to the high calorie nutrient composition for the purpose of processing or storing the high calorie nutrient composition.
  • food additives in addition to the purpose of fortification, for example, zinc gluconate and copper gluconate, ascorbic acid 2-glucoside, cyclodextrin, preservatives, fungicides, antioxidants, coloring agents, masking agents, pH adjusters, acidulants, flavors, antifoaming agents, etc.
  • Ascorbic acid 2-glucoside is a compound in which glucose is bonded to the hydroxyl group at the 2-position of vitamin C (ascorbic acid) by ⁇ -coordination, and is a vitamin with higher stability than ordinary vitamin C because it is not attacked by oxygen. C derivative. Ascorbic acid 2-glucoside can efficiently absorb vitamin C. The content of ascorbic acid 2-glucoside is appropriately adjusted by the subject or the like who applies the high calorie nutritional composition.
  • Cyclodextrin is a cyclic oligosaccharide having a cyclic structure in which glucose is linked by a glucosidic bond. Those consisting of six glucose are called ⁇ -cyclodextrin, those consisting of seven glucose are called ⁇ -cyclodextrin, and those consisting of eight glucose are called ⁇ -cyclodextrin. Cyclodextrins have functions such as an allergy suppressive effect, a blood glucose level increase suppressive effect, and an emulsifying action. Cyclodextrin may be used alone or as a mixture of two or more. The content of cyclodextrin is appropriately adjusted by the subject or the like who applies the high calorie nutrient composition.
  • the antioxidant has a function of preventing deterioration due to oxidation.
  • the antioxidant is not particularly limited, and ascorbic acid and its sodium salt, erythorbic acid and its sodium salt, etc. may be used. These antioxidants may be used alone or in combination of two or more.
  • the colorant has the function of making the high calorie nutritional composition look beautiful. Although it does not specifically limit as a coloring agent, Edible tar pigment (edible red 2, 3, 40, 102, 104, 105, and 106, Edible blue 1 and 2, Edible yellow 4, Edible yellow 4 And 5, food green No.
  • Edible tar pigment edible red 2, 3, 40, 102, 104, 105, and 106, Edible blue 1 and 2, Edible yellow 4, Edible yellow 4 And 5, food green No.
  • ⁇ -carotene water-soluble anatto, chlorophyll derivatives (chlorophyll a, chlorophyll b, copper chlorophyll, sodium copper chlorophyllin, sodium iron chlorophyllin etc), riboflavin, ferric oxide, titanium dioxide, Examples thereof include safflower yellow pigment, cochineal pigment, gardenia yellow pigment, turmeric pigment, red cabbage pigment, beet red, grape skin pigment, paprika pigment, caramel and the like. These colorants may be used alone or in combination of two or more.
  • the masking agent has a function to suppress and hide unique bitter taste and the like derived from the raw material in the high calorie nutritional composition.
  • the masking agent is not particularly limited, but saccharin and its sodium salt, xylitol, aspartame, sucralose, acesulfame potassium, duculin, ticlo (cyclamic acid), neotame, trehalose, erythritol, maltose, palatinose, sorbitol, licorice extract, stevia , Thaumatin, curculin, disodium lytyllithium acid and the like. These masking agents may be used alone or in combination of two or more.
  • the pH adjuster has a function of adjusting the pH of the high calorie nutrient composition.
  • the pH adjuster is not particularly limited, and citric acid, gluconic acid, succinic acid, potassium carbonate, sodium hydrogencarbonate, carbon dioxide, lactic acid, sodium lactate, sodium citrate, adipic acid and the like may be used. These pH adjusters may be used alone or in combination of two or more.
  • the pH is 3.0 or more and 4.0 or less, and it is more preferable that it is about 4.0 by adjusting pH by a pH adjuster. If the pH in the high-calorie nutrition composition is less than 3.0, the sour taste is felt strongly and the flavor may be lost. If the pH in the high-calorie nutrition composition exceeds 4.0, the possibility of propagation of microorganisms such as fungi is increased, and the safety as a food may not be maintained. Thereby, while being able to aim at long-term stabilization of a high-calorie nutrition composition, when eating a high-calorie nutrition composition, a user can eat without feeling strong sourness.
  • the acidulant has functions such as addition of acidity to a high calorie nutrient composition, prevention of oxidation of the high calorie nutrient composition, and adjustment of pH.
  • the acidulant include, but are not limited to, acetic acid, citric acid, succinic acid, lactic acid, malic acid, tartaric acid, gluconic acid, and phosphoric acid. These acidulants may be used alone or in combination of two or more.
  • the flavor has the function of flavoring and deodorizing the high calorie nutritional composition.
  • the flavor include, but are not limited to, acetophenone, ⁇ -amylcinnamaldehyde, anisaldehyde, benzaldehyde, benzyl acetate, benzyl acetate, benzyl alcohol, cinnamaldehyde, cinnamic acid, citral, citronellal, citronellol, decanol, decanol, ethyl acetoacetate, silica Ethyl benzoate, ethyl decanoate, ethyl vanillin, eugenol, geraniol, isoamyl acetate, isoamyl butyrate, isoamyl phenylacetate, dl-menthol, l-menthol, methyl salicylate, piperonal, propionic acid, terpineol, vanillin
  • Stabilizers have the function of contributing to the stabilization of the manufacturing process as well as the texture improvement of the high calorie nutritional composition.
  • the stabilizer generally used can be used. Specifically, for example, agar, gelatin, cellulose, chitin, dextran, branched dextran, glycogen, inulin, mannan, glucomannan, xylan, pullulan, alginic acid, alginic acid salt, carboxymethylcellulose, hydroxypropylcellulose, cyclodextrin, phalcerodine, Modified starch, carrageenan, pectin, locust bean gum, guar gum, guar gum decomposition product, xanthan gum, tamarind gum, gum arabic, gellan gum, vegetable protein, vegetable protein decomposition product, animal protein, animal protein decomposition product, etc. may be mentioned. .
  • These stabilizers may be used alone, or two or more may be mixed and used as a stabilizer.
  • agar for example, ultra-quick dissolving agar UX-30, ultra-quick dissolving agar UX-100, ultra-quick dissolving agar UX-200, Ultra Agar AX-30, Ultra Agar AX-100, Ultra Agar AX-200, Ultra Agar BX-30, Ultra Agar BX-100, Ultra Agar BX-200, Ultra Agar Eana, Ina Agar
  • pectin include, for example, GENU pectin YM-150-LJ, GENU pectin YM-150-LJ-TF, GENU pectin YM-115-HJ, GENU pectin YM-115-.
  • a stabilizer can also serve as the effect as a dietary fiber mentioned above.
  • the content of the stabilizer is appropriately adjusted in consideration of the texture, stability and the like.
  • the high-calorie nutrition composition contains the above-mentioned dietary fiber as a functional component and agar which functions as a stabilizer.
  • agar in the high-calorie nutrition composition, the function as a dietary fiber and stabilizer is exerted on the agar, and the high-calorie nutrition composition is excellent in protein, lipid and carbohydrate as a major nutrient. It can be dispersed without separation with stability, and stabilization can be achieved. Furthermore, the viscosity at 25 ° C.
  • the high-calorie nutrition composition is within the above-mentioned range, ie, 3500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less, preferably 5,000 mPa ⁇ s or more and 15,000 mPa ⁇ s or less Can be set easily.
  • the content of agar in the high calorie nutritional composition is preferably 0.05 g or more and 0.32 g or less in 100 mL, and more preferably 0.12 g or more and 0.30 g or less.
  • the viscosity at 25 degrees C of a high calorie nutrient composition can be set more reliably within the range mentioned above.
  • the high-calorie nutrition composition contains, in addition to the nutrients and agar, a carbohydrate (polysaccharide), dietary fiber and pectin as a stabilizer.
  • a carbohydrate polysaccharide
  • pectin as a stabilizer.
  • the viscosity at 25 degrees C of a high calorie nutrient composition can be set more reliably within the range mentioned above.
  • the content of pectin in the high-calorie nutrition composition is set to 100 g, preferably 0.05 g or more and 0.3 g or less, more preferably 0.1 g or more and 0.2 g or less. Thereby, the said effect can be exhibited more notably.
  • additives for example, enzymes such as ⁇ -amylase, ⁇ -amylase, glucoamylase, glucose isomerase, trehalose producing enzyme, trehalose releasing enzyme, glutaminase, yeast and the like are used.
  • the content of these other additives is appropriately adjusted by the subject or the like who applies the high calorie nutrient composition.
  • the above-mentioned high-calorie nutrition composition can be manufactured by a well-known method.
  • the container 10 in the present embodiment is an aluminum pouch with a straw, which is filled with the above-described high-calorie nutrition composition, and is used as a container when carrying (transporting) and ingesting this high-calorie nutrition composition. It also has a function.
  • the container 10 is a bag-shaped container body 30 to be filled with a high-calorie nutrition composition, and an opening 20 provided at the upper end of the container body 30 and communicating with the container body 30. And a lid 25 detachably provided in the opening 20.
  • the container body 30 is a gusset-type pouch container having a rectangular shape in a plan view shape and having a folded portion folded inward on both sides, and the height thereof is 100 mL so that the volume is 100 mL. It is set to A120 mm x width B 80 mm x gusset width 21 mm.
  • the container body 30 is filled with a high-calorie nutritional composition having a heat quantity of 2.5 kcal / mL or more and 4.5 kcal / mL or less, and the filling amount is 100 mL. Therefore, it is possible to obtain energy of 750 kcal or more and 1350 kcal or less by, for example, acquiring the high-calorie nutrition composition filled in the container body 30 with the package 1 at breakfast, lunch, and dinner three meals. is there. Therefore, by the intake of three meals of the high-calorie nutrition composition by the package 1, it is possible to satisfy the amount of energy that it is desirable for the elderly to obtain in one day.
  • the ingested person who ingests the high-calorie nutrition composition gets the elderly person in one day only by eating a small amount of the high-calorie nutrition composition said to be 100 mL filled in the container body 30 The amount of energy desired to be achieved is achieved.
  • the container 10 (container body 30) is not limited to the case where the volume is 100 mL as described above, and may have a volume of about 50 mL to 200 mL. If it has the capacity
  • the container body 30 is made of, for example, a film material in which both surfaces of an aluminum foil are coated with a covering layer made of a resin material.
  • the opening 20 has a cylindrical shape as a whole and is provided substantially at the center of the upper end of the container body 30, thereby functioning as a straw communicating with the container body 30.
  • the high-calorie nutrition composition is filled in the container body 30 at the time of manufacturing the package 1 through the opening 20, and when the high-calorie nutrition composition is eaten by the user, The pressure is discharged from the container body 30.
  • the inner diameter (diameter) of the opening 20 is set to 8.33 mm in the present embodiment.
  • the internal diameter (opening diameter) is set to such a size, and as described above, the high-calorie nutrition composition having a viscosity of 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less at 25 ° C.
  • the user can easily discharge the high-calorie nutrition composition from the container body 30 through the opening 20 by pressing the container body 30 without causing dripping, and then orally A high calorie nutritional composition can be obtained (eating) by the consumer.
  • the discharge pressure for pressing the container body 30 is preferably 20 kPa or less, more preferably 10 kPa or less It can be set to As a result, even a user who has a reduced grip, such as an elderly person, can discharge the high-calorie nutrition composition from the container body 30 through the opening 20 by pressing the container body 30 by hand. can do.
  • the opening 20 is provided with a male screw (not shown) on the upper end side of the outer peripheral surface thereof.
  • the lid 25 is in the form of a cylinder having an overall shape with a bottom and is provided with a female screw (not shown) on the inner peripheral surface thereof.
  • the lid 25 is removable, as shown in FIG. 1, when the package 1 is transported and stored, the lid 25 is put in a mounted state, and the sealing performance of the opening 20 and the container body 30 is secured. At the time of filling of the high-calorie nutrition composition into the main body 30 and at the time of intake of the high-calorie nutrition composition, the body 30 is in a state of being loaded and unloaded, and filling and discharge of the high-calorie nutrition composition through the opening 20 become possible.
  • the opening 20 and the lid 25 are made of, for example, a resin material such as high density polyethylene (HDPE).
  • HDPE high density polyethylene
  • the packaging body 1 is commercialized by filling the container body 30 with the high-calorie nutrition composition after being continuously sterilized.
  • the continuous sterilization method is not particularly limited, and examples thereof include ultra-high-temperature short-time (UHT) sterilization, hot water sterilization, batch sterilization, and a combination thereof.
  • UHT ultra-high-temperature short-time
  • the container 10 filled with the high-calorie nutrition composition ie, the container 10 provided in the package 1 is not limited to the aluminum pouch with straw described in the present embodiment, for example, other known containers may be used.
  • this container tetra-pack, cart can, glass container, metal can, plastic container etc. may be mentioned.
  • the high-calorie nutrition composition can be applied not only to a liquid food to be taken orally but also to an enteral nutrient for enteral administration via a PEG tube or the like.
  • the high calorie nutrition composition and the package of the present invention were explained based on a suitable embodiment, the present invention is not limited to these.
  • the various nutrients contained in the high calorie nutritional composition of the present invention can be replaced with any one capable of performing the same function, or one having an arbitrary function can be added.
  • Example 1A Examination of agar content (Example 1A) The method of preparation at the time of 1700L preparation is described below. The blending amounts of the respective raw materials are as shown in Table 1.
  • the mixed solution was mixed with vegetable mixed oil and medium chain fatty acid at 65 ° C.
  • the solution obtained was homogenized, filled in an aluminum pouch with a straw (plug) (see FIG. 1) so as to be 100 mL per one, and then sterilized at 90 ° C. for 10 minutes. It cooled after the said sterilizing process, and manufactured the package body with which the high calorie nutrient composition (high concentration nutrient composition) was filled.
  • the content of protein is 14.0 g / 100 mL (the concentration of collagen peptide is 10.0 g / 100 mL, the concentration of whey protein is 4.00 g / 100 mL), and the content of carbohydrate is The content of 37.4 g / 100 mL and lipid was 21.6 g / 100 mL.
  • the evaluation method is as follows.
  • Viscosity After leaving the nutritional composition at rest for 24 hours at 25 ° C., a B-type rotational viscometer (Manufacturer: BROOKFIELD, Model: DV-II + Pro, measurement conditions: rotational speed 6 rpm, measurement time 1 minute, rotor No. 63) ) was used.
  • Presence or absence of liquid dripping 100 mL of the nutritional composition is filled in the container 10 shown in FIG. 1, and thereafter, the presence or absence of liquid dripping from the opening 20, and further, the nutritional composition when the container main body 30 is pressed The ease of discharge of (content) was observed.
  • No dripping and the nutritional composition is easily discharged by the pressure of the container body 30.
  • x Liquid dripping is recognized, or the nutritional composition is not easily discharged even by the pressure of the container body 30.
  • Calorific value of the obtained nutritional composition is 4.0 kcal / mL, uniformity is " ⁇ ", pH is 3.8, agar content is 0.12 g / 100 mL, viscosity is 7,785 ⁇ 269 mPa ⁇ s, stable The sex was " ⁇ ” and the presence or absence of the liquid was “ ⁇ ".
  • Table 2 The results are shown in Table 2.
  • Example 2A The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.05 g / 100 mL in Example 2A.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “ ⁇ ”, the pH is 3.8, the viscosity is 3,753 ⁇ 254 mPa ⁇ s, the stability is “ ⁇ ”, the presence or absence of liquid drip is It was “ ⁇ ”.
  • the results are shown in Table 2.
  • Example 3A The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.24 g / 100 mL in Example 3A.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is " ⁇ ", the pH is 3.8, the viscosity is 12,930 ⁇ 372 mPa ⁇ s, the stability is " ⁇ ”, the presence or absence of liquid drip is It was “ ⁇ ”.
  • the results are shown in Table 2.
  • Example 4A The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.30 g / 100 mL in Example 4A.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is " ⁇ ", the pH is 3.8, the viscosity is 14,484 ⁇ 811 mPa ⁇ s, the stability is " ⁇ ", the presence or absence of liquid drip It was “ ⁇ ”.
  • the results are shown in Table 2.
  • Example 5A The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed such that the content of agar was 0.32 g / 100 mL in Example 5A.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is " ⁇ ", the pH is 3.8, the viscosity is 17,093 ⁇ 600 mPa ⁇ s, the stability is " ⁇ ", the presence or absence of liquid drip is It was “ ⁇ ”.
  • the results are shown in Table 2.
  • Comparative example 1A a nutritional composition was obtained by repeating the same preparation method as Example 1A except that addition of agar was omitted so that the agar content was 0.00 g / 100 mL.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “ ⁇ ”, the pH is 3.8, the viscosity is 2,719 ⁇ 140 mPa ⁇ s, the stability is “x”, the presence or absence of liquid drip is It was "x”.
  • the results are shown in Table 2.
  • Comparative example 2A a nutritional composition was obtained by repeating the same preparation method as Example 1A except that the amount of agar added was changed so that the agar content was 0.35 g / 100 mL.
  • the heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “ ⁇ ”, the pH is 3.8, the viscosity is 25,128 ⁇ 2663 mPa ⁇ s, the stability is“ x ”, the presence or absence of dripping is It was "x”.
  • the results are shown in Table 2.
  • the viscosity of the nutritional composition at 25 ° C. is set by setting the agar content in the nutritional composition to an appropriate range in comparison with each comparative example. It is set in the range of 3,500 mPa ⁇ s or more and 17,500 mPa ⁇ s or less, which makes it possible to achieve uniformity and stability of the nutritional composition, and it is also apparent that no dripping from the container is observed. became.
  • the high-calorie nutrition composition of the present invention contains a nutrient containing protein, lipid and carbohydrate, and agar, has a viscosity at 25 ° C. of not less than 3,500 mPa ⁇ s and not more than 17,500 mPa ⁇ s, and has an amount of heat of 2.5 kcal / mL or more and 4.5 kcal / mL or less. Therefore, it is possible to supply a sufficient amount of energy with a small amount of intake and to obtain three major nutrients in a balanced manner, and to separate proteins, lipids and carbohydrates as major nutrients with excellent stability.
  • the high calorie nutritional composition and package of the present invention have industrial applicability.

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Abstract

Provided is a high-calorie nutritional composition which contains agar and nutrients including proteins, lipids, and carbohydrates, and which has a viscosity of 3,500-17,500 mPa•s at 25°C and a caloric value of 2.5-4.5 kcal/mL.

Description

高カロリー栄養組成物および包装体High calorie nutritional composition and package
 本発明は、主に経口または経管により栄養素を補給するための高カロリー栄養組成物および包装体に関する。 The present invention relates to a high calorie nutritional composition and package mainly for supplying nutrients by oral or gavage.
 近年、高齢化に伴い、日常の食生活で不足しがちな栄養素を補給するための高カロリー栄養組成物が注目されており、これまでに種々の栄養剤が提案され市販されている(例えば、特許文献1参照)。 BACKGROUND ART In recent years, with the aging of the population, high-calorie nutritional compositions for supplementing nutrients that are likely to be lacking in daily diet have attracted attention, and various nutritional agents have been proposed and marketed so far (for example, Patent Document 1).
 特に、食欲が低下していたり、嚥下障害を伴う高齢者に対しては、少量の高カロリー栄養組成物の摂取により、エネルギーを十分に補給することができるとともに、三大栄養素をバランスよく取得することが求められ、さらに、三大栄養素としてのたんぱく質、脂質および炭水化物が高カロリー栄養組成物中に優れた安定性をもって分離することなく分散していることが求められる。 In particular, for elderly people with decreased appetite or dysphagia, intake of a small amount of high-calorie nutrition composition can provide sufficient energy supplementation and obtain well-balanced nutrition of the three major nutrients. In addition, it is required that proteins, lipids and carbohydrates as major nutrients are dispersed in a high-calorie nutritional composition with good stability without separation.
 また、この高カロリー栄養組成物が充填された包装体から、液だれを生じさせることなく、容易に高カロリー栄養組成物を補給できることが求められる。 Moreover, it is calculated | required that a high calorie nutrient composition can be easily replenished from the package filled with this high calorie nutrient composition, without producing a dripping.
特開2015-107075号公報JP, 2015-107075, A
 本発明の目的は、少量の摂取によりエネルギーを十分に補給することができるとともに、三大栄養素をバランスよく取得することができ、かつ、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散している高カロリー栄養組成物、および、かかる高カロリー栄養組成物が容器に充填され、この高カロリー栄養組成物を、液だれを生じさせることなく、容易に補給することができる包装体を提供することにある。 The object of the present invention is to provide a sufficient supply of energy by intake of a small amount, and to obtain three major nutrients in a well-balanced manner, and an excellent stability of proteins, lipids and carbohydrates as major nutrients. A high-calorie nutritional composition dispersed without separation with the water, and such a high-calorie nutrition composition filled in a container, and the high-calorie nutrition composition is easily replenished without causing dripping To provide a package that can
 このような目的は、下記(1)~(9)の本発明により達成される。
 (1) たんぱく質、脂質、炭水化物を含む栄養素と、寒天を含有する高カロリー栄養組成物であって、
 25℃での粘度が3,500mPa・s以上17,500mPa・s以下であり、かつ、熱量が2.5kcal/mL以上4.5kcal/mL以下であることを特徴とする高カロリー栄養組成物。
Such an object is achieved by the present invention of the following (1) to (9).
(1) A high-calorie nutritional composition comprising nutrients including protein, lipids, carbohydrates and agar,
A high-calorie nutritional composition characterized in that the viscosity at 25 ° C. is 3,500 mPa · s or more and 17,500 mPa · s or less, and the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less.
 (2) さらに、ペクチンを含有する上記(1)に記載の高カロリー栄養組成物。
 (3) pHが3.0以上4.0以下である上記(1)または(2)に記載の高カロリー栄養組成物。
(2) The high calorie nutrient composition according to the above (1), further comprising pectin.
(3) The high calorie nutrient composition according to the above (1) or (2), which has a pH of 3.0 or more and 4.0 or less.
 (4) 当該高カロリー栄養組成物における、前記寒天の含有量は、100mL中、0.05g以上0.32g以下である上記(1)ないし(3)のいずれかに記載の高カロリー栄養組成物。 (4) The high calorie nutrient composition according to any one of the above (1) to (3), wherein the content of the agar in the high calorie nutrient composition is 0.05 g or more and 0.32 g or less in 100 mL. .
 (5) 当該高カロリー栄養組成物における、前記たんぱく質の含有量は、100mL中、10.0g以上30.0g以下である上記(1)ないし(4)のいずれかに記載の高カロリー栄養組成物。 (5) The high calorie nutritional composition according to any one of the above (1) to (4), wherein the content of the protein in the high calorie nutritional composition is 10.0 g or more and 30.0 g or less in 100 mL. .
 (6) 前記たんぱく質として、コラーゲンペプチドおよび乳清たんぱく質を含有する上記(1ないし5のいずれか1項に記載の高カロリー栄養組成物。 (6) The high calorie nutrient composition according to any one of the above (1 to 5), which contains a collagen peptide and whey protein as the protein.
 (7) 当該高カロリー栄養組成物における、前記脂質の含有量は、100mL中、8.0g以上30.0g以下である上記(1)ないし(6)のいずれかに記載の高カロリー栄養組成物。 (7) The high calorie nutrition composition according to any one of the above (1) to (6), wherein the content of the lipid in the high calorie nutrition composition is 8.0 g or more and 30.0 g or less in 100 mL. .
 (8) 当該高カロリー栄養組成物における、前記炭水化物の含有量は、100mL中、25.0g以上40.0g以下である上記(1)ないし(7)のいずれかに記載の高カロリー栄養組成物。 (8) The high calorie nutritional composition according to any one of the above (1) to (7), wherein the content of the carbohydrate in the high calorie nutritional composition is 25.0 g or more and 40.0 g or less in 100 mL. .
 (9) 上記(1)ないし(8)のいずれかに記載の高カロリー栄養組成物と、前記高カロリー栄養組成物を充填した容器とを有することを特徴とする包装体。 (9) A package comprising the high calorie nutritional composition according to any one of the above (1) to (8) and a container filled with the high calorie nutritional composition.
 本発明の高カロリー栄養組成物によれば、高カロリー栄養組成物の少量の摂取によっても、エネルギーを十分に補給することができるとともに、三大栄養素をバランスよく取得することができる。また、高カロリー栄養組成物中において、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散されており、安定化が図られた高カロリー栄養組成物とすることができる。 According to the high-calorie nutrition composition of the present invention, energy can be sufficiently replenished even by intake of a small amount of the high-calorie nutrition composition, and the three major nutrients can be acquired in a well-balanced manner. In addition, in a high calorie nutrient composition, a protein, lipid and carbohydrate as major nutrients are dispersed without separation with excellent stability, and a stabilized high calorie nutrition composition is provided. it can.
 さらに、本発明の包装体においては、本発明の高カロリー栄養組成物が容器に充填されることにより、この容器すなわち包装体の小型化を実現することができるとともに、容器に充填された高カロリー栄養組成物を、液だれを生じさせることなく、摂取者が容易に補給することができる。 Furthermore, in the package of the present invention, by filling the container with the high calorie nutrient composition of the present invention, miniaturization of the container, that is, the package can be realized, and the high calorie filled in the container is achieved. The nutritional composition can be easily replenished by the consumer without causing dripping.
図1は、本発明の包装体の好適実施形態を示す斜視図である。FIG. 1 is a perspective view showing a preferred embodiment of the package of the present invention.
 以下、本発明の高カロリー栄養組成物および包装体を好適実施形態に基づいて詳細に説明する。 Hereinafter, the high calorie nutrient composition and the package of the present invention will be described in detail based on preferred embodiments.
 本発明の高カロリー栄養組成物は、たんぱく質、脂質、炭水化物を含む栄養素と、寒天とを含有するものであり、25℃での粘度が3,500mPa・s以上17,500mPa・s以下であり、かつ、熱量が2.5kcal/mL以上4.5kcal/mL以下であることを特徴とする。これにより、高カロリー栄養組成物の少量の摂取によっても、エネルギーを十分に補給することができるとともに、三大栄養素をバランスよく取得することができる。また、高カロリー栄養組成物中において、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散されており、安定化が図られた高カロリー栄養組成物とすることができる。さらに、本発明の包装体においては、本発明の高カロリー栄養組成物が容器に充填されることにより、この容器すなわち包装体の小型化を実現することができるとともに、容器に充填された高カロリー栄養組成物を、液だれを生じさせることなく、摂取者が容易に補給することができる。 The high calorie nutrient composition of the present invention contains a nutrient containing protein, lipid and carbohydrate, and agar, and has a viscosity of 3,500 mPa · s or more and 17,500 mPa · s or less at 25 ° C. And, it is characterized in that the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less. Thereby, energy can be sufficiently replenished by intake of a small amount of the high-calorie nutrition composition, and three major nutrients can be acquired in a well-balanced manner. In addition, in a high calorie nutrient composition, a protein, lipid and carbohydrate as major nutrients are dispersed without separation with excellent stability, and a stabilized high calorie nutrition composition is provided. it can. Furthermore, in the package of the present invention, by filling the container with the high calorie nutrient composition of the present invention, miniaturization of the container, that is, the package can be realized, and the high calorie filled in the container is achieved. The nutritional composition can be easily replenished by the consumer without causing dripping.
 以下、本発明の高カロリー栄養組成物が容器内に充填された包装体(本発明の包装体)について説明する。なお、以下では、本発明の包装体が備える容器を、ストロー付きアルミパウチに適用した場合を一例に説明する。 Hereinafter, the package (packing body of this invention) with which the high-calorie nutrition composition of this invention was filled in the container is demonstrated. In addition, below, the case where the container with which the package of this invention is provided is applied to the aluminum pouch with a straw is demonstrated to an example.
<包装体>
 図1は、本発明の包装体の好適実施形態を示す斜視図である。なお、以下では、説明の都合上、図1中の上側を「上」または「上方」、下側を「下」または「下方」と言う。
<Packaging body>
FIG. 1 is a perspective view showing a preferred embodiment of the package of the present invention. In the following, for convenience of explanation, the upper side in FIG. 1 is referred to as “upper” or “upper” and the lower side as “lower” or “lower”.
 図1に示すように、包装体1は、容器10と、この容器10内に充填された高カロリー栄養組成物(図示せず)とを有する。 As shown in FIG. 1, the package 1 has a container 10 and a high-calorie nutrition composition (not shown) filled in the container 10.
<<高カロリー栄養組成物>>
 高カロリー栄養組成物は、容器10内に充填されており、前述の通り、本発明では、栄養素(三大栄養素)として、たんぱく質と、脂質と、炭水化物とを含み、さらに、寒天を含んでおり、25℃での粘度が3,500mPa・s以上17,500mPa・s以下であり、かつ、その熱量が2.5kcal/mL以上4.5kcal/mL以下となっている。
<< High Calorie Nutritional Composition >>
The high-calorie nutrition composition is filled in the container 10, and as described above, according to the present invention, it contains protein, lipid and carbohydrate as nutrients (three major nutrients) and further contains agar. The viscosity at 25 ° C. is 3,500 mPa · s or more and 17,500 mPa · s or less, and the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less.
 以下、これら栄養素等について、順次、説明する。
 たんぱく質は、窒素源やアミノ酸を供給するための栄養素(三大栄養素)として、高カロリー栄養組成物に含まれる。
Hereinafter, these nutrients and the like will be described one by one.
Protein is included in the high calorie nutrient composition as a nutrient (a major nutrient) for supplying a nitrogen source and an amino acid.
 高カロリー栄養組成物中における、たんぱく質の含有量は、高カロリー栄養組成物100mL中、好ましくは10.0g以上30.0g以下程度、より好ましくは12.0g以上16.0g以下程度に設定される。これにより、三大栄養素をバランスよく取得することができるとともに、高カロリー栄養組成物の熱量を2.5kcal/mL以上4.5kcal/mL以下に設定できることから、高カロリー栄養組成物の少量(例えば100mL)の摂取、すなわち、包装体1に充填された高カロリー栄養組成物の摂取によって、エネルギーを十分に補給することができる。 The content of the protein in the high-calorie nutrition composition is set to preferably about 10.0 g to about 30.0 g, more preferably about 12.0 g to about 16.0 g, in 100 mL of the high-calorie nutrition composition. . As a result, the three major nutrients can be acquired in a well-balanced manner, and the amount of heat of the high calorie nutrient composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less. Energy can be sufficiently replenished by the intake of 100 mL, that is, the intake of the high-calorie nutritional composition filled in the package 1.
 なお、本明細書中において、たんぱく質とは、アミノ酸の重合度に関係なく低分子のものも含まれ、たんぱく質の他、たんぱく質の分解物としてのアミノ酸およびペプチドを含むこととする。 In the present specification, protein includes low molecular weight proteins irrespective of the degree of polymerization of amino acids, and includes proteins as well as amino acids and peptides as protein degradation products.
 このたんぱく質として、コラーゲンペプチドおよび乳清たんぱく質を含むことが好ましい。 Preferably, the protein includes collagen peptide and whey protein.
 乳清たんぱく質は、牛乳が凝固する際に残存する乳清(ホエイ)から単離される球状たんぱく質の混合物であり、牛乳に含まれる可溶成分からなるものである。 Whey protein is a mixture of globular proteins isolated from whey (whey) remaining when milk is coagulated, and consists of soluble components contained in milk.
 この乳清たんぱく質としては、例えば、市販されているものを用いることができ、具体的には、WPC550(Fonterra社製)、エンラクトHG(日本新薬株式会社製)、エンラクトCC(日本新薬株式会社製)、PROGEL800(日本新薬株式会社製)、ラクトクリスタル(日本新薬株式会社製)、WPI18855(Fonterra社製)、WPI18822(Fonterra社製)、WPI1895(Fonterra社製)、WPC392(Fonterra社製)、WPC80(Fonterra社製)、WPC7009(Fonterra社製)、WPC164(Fonterra社製)、WPC162(Fonterra社製)、WPC132(Fonterra社製)、WPC472(Fonterra社製)等が挙げられる。 As this whey protein, for example, a commercially available one can be used. Specifically, WPC550 (made by Fonterra), Enlacto HG (made by Nippon Shinyaku Co., Ltd.), Entract CC (made by Nippon Shinyaku Co., Ltd.) PROGEL 800 (manufactured by Nippon Shinyaku Co., Ltd.), Lactocrystal (manufactured by Nippon Shinyaku Co., Ltd.), WPI 18855 (manufactured by Fonterra), WPI 18822 (manufactured by Fonterra), WPI 1895 (manufactured by Fonterra), WPC 392 (manufactured by Fonterra), WPC 80 (Manufactured by Fonterra), WPC 7009 (manufactured by Fonterra), WPC 164 (manufactured by Fonterra), WPC 162 (manufactured by Fonterra), WPC 132 (manufactured by Fonterra), WPC 472 (Fonterra) Ltd.) and the like.
 また、コラーゲンペプチドは、動物(主として豚、鶏および魚)由来のコラーゲンを酵素等により加水分解することで、好ましくは1,000以上8,500以下程度、より好ましくは1,000以上5,000以下程度の重量平均分子量に低分子化したものである。 The collagen peptide is preferably about 1,000 or more and 8,500 or less, more preferably 1,000 or more and 5,000 or less by hydrolyzing collagen derived from an animal (mainly pig, chicken and fish) with an enzyme or the like. The molecular weight is reduced to the following weight average molecular weight.
 このコラーゲンペプチドは、市販品として、例えば、豚由来、鶏由来、魚由来のコラーゲンペプチドが挙げられ、具体的には、豚コラーゲン由来のウェルコラーゲン(日本新薬株式会社製)、SOLUGEL(日本ピュアフード株式会社製)、GELITA SOL NPE(株式会社ニッピ製)、GELITA SOL NPS(株式会社ニッピ製)、魚コラーゲン由来のマリンコラーゲンNH(日本ハム株式会社製)および鶏コラーゲン由来のC-LAP(日本ハム株式会社製)等が挙げられる。 Examples of commercially available collagen peptides include pig-derived, chicken-derived, and fish-derived collagen peptides. Specifically, porcine collagen-derived well collagen (manufactured by Nippon Shinyaku Co., Ltd.), SOLUGEL (Nippon Pure Food Co., Ltd.) GELITA SOL NPE (Nippi Co., Ltd.), GELITA SOL NPS (Nippi Co., Ltd.), Marine collagen NH derived from fish collagen (Nippon Ham Co., Ltd.) and C-LAP derived from chicken collagen (Nippon Ham Co., Ltd.) And the like.
 これらのコラーゲンペプチドおよび乳清たんぱく質を、高カロリー栄養組成物における、乳清たんぱく質の重量含有量を1.0としたとき、コラーゲンペプチドの重量含有量が1.0以上26.0以下となっていることが好ましい。これにより、高カロリー栄養組成物を、その少量の摂取によってもエネルギーを十分に補給することができるものとしつつ、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散されており、安定化が図られたものとすることができる。また、コラーゲンペプチドの重量含有量が1.0未満の場合、高カロリー栄養組成物の少量の摂取によってはエネルギーを十分に補給することが困難となるおそれがある。さらに、コラーゲンペプチドの重量含有量が26.0を超えると、高カロリー栄養組成物に独特の臭みや、えぐ味、苦味等の不快に感じる風味が発生し、高カロリー栄養組成物を摂取する摂取者が美味しく食することができず、摂取者の食欲が低下するため、クオリティーオブライフ(QOL)の低下を招くおそれがある。 When the weight content of whey protein in the high calorie nutritional composition is 1.0, the weight content of collagen peptide is 1.0 or more and 26.0 or less for these collagen peptides and whey proteins. Is preferred. Thus, while making it possible to supply a high calorie nutritional composition with sufficient energy even with a small amount of intake, it disperses proteins, lipids and carbohydrates as major nutrients without separating with excellent stability. And can be stabilized. In addition, if the weight content of the collagen peptide is less than 1.0, it may be difficult to sufficiently replenish energy by ingesting a small amount of the high calorie nutrient composition. Furthermore, when the weight content of the collagen peptide exceeds 26.0, the high-calorie nutritive composition has a distinctive smell, unpleasant flavor such as bitter taste, bitter taste and the like, and the ingestion of the high-calorie nutritive composition is consumed It is not possible for a person to eat deliciously, and the appetite of the user is reduced, which may lead to a decrease in quality of life (QOL).
 なお、コラーゲンペプチドの重量含有量は、乳清たんぱく質の重量含有量を1.0としたとき、1.0以上26.0以下であることが好ましいが、1.7以上4.3以下であることがより好ましい。これにより、高カロリー栄養組成物を、より安定化が図られたものとすることができる。 The weight content of collagen peptide is preferably 1.0 or more and 26.0 or less when the weight content of whey protein is 1.0, but is 1.7 or more and 4.3 or less Is more preferred. Thereby, the high calorie nutritional composition can be made more stabilized.
 なお、たんぱく質としては、コラーゲンペプチドおよび乳清たんぱく質以外のものを含んでいてもよく、例えば、コラーゲンペプチドおよび乳清たんぱく質以外の動物性たんぱく質や植物性たんぱく質等の公知のものを用いることができる。 The proteins may contain proteins other than collagen peptides and whey proteins, and, for example, known proteins such as animal proteins and vegetable proteins other than collagen peptides and whey proteins can be used.
 このたんぱく質としては、例えば、乳清たんぱく質を除く牛乳等に含まれるたんぱく質、大豆たんぱく等が挙げられる。 Examples of this protein include proteins contained in milk etc. excluding whey protein, soybean protein and the like.
 より具体的には、牛乳を原料とするものとして、例えば、カゼイン、カゼイネート、トータルミルクプロテイン(TMP)、ミルクプロテインコンセントレート(MPC)が挙げられ、大豆を原料とするものとして、例えば、大豆たんぱくが挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 More specifically, examples using milk as a raw material include casein, caseinate, total milk protein (TMP), milk protein concentrate (MPC), and examples using soy as a raw material include soybean protein These may be used alone or in combination of two or more.
 なお、TMP、MPCや、大豆たんぱく等は市販されているものを用いることができ、市販品としては、例えば、MPC80(日本新薬株式会社製)、MPC80LR(日本新薬株式会社製)、カゼインマグネシウムS(日本新薬株式会社製)、カゼインカリウムS(日本新薬株式会社製)、カゼインナトリウムCW(日本新薬株式会社製)、プロリーナ900(不二製油株式会社製)、プロリーナ700(不二製油株式会社製)、プロリーナ800(不二製油株式会社製)、ニューフジプロ3000(不二製油株式会社製)、ニューフジプロ1700N(不二製油株式会社製)等が挙げられる。 In addition, TMP, MPC, soybean protein etc. can use what is marketed, and as a commercial item, MPC80 (made by Nippon Shinyaku Co., Ltd.), MPC80LR (made by Nippon Shinyaku Co., Ltd.), casein magnesium S, for example (Nippon Shinyaku Co., Ltd.), Casein potassium S (Nippon Shinyaku Co., Ltd.), Casein sodium CW (Nippon Shinyaku Co., Ltd.), Prorina 900 (Fuji Oil Co., Ltd.), Prorina 700 (Fuji Oil Co., Ltd.) , Prolina 800 (manufactured by Fuji Oil Co., Ltd.), New Fuji Pro 3000 (manufactured by Fuji Oil Co., Ltd.), New Fuji Pro 1700 N (manufactured by Fuji Oil Co., Ltd.), and the like.
 また、アミノ酸としては、例えば、バリン、ロイシン、イソロイシン、リシン、メチオニン、フェニルアラニン、トレオニン、トリプトファン、ヒスチジン等の必須アミノ酸、およびグリシン、アラニン、セリン、システイン、アスパラギン、グルタミン、プロリン、チロシン、アスパラギン酸、グルタミン酸、アルギニン等の非必須アミノ酸が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Also, as the amino acids, for example, essential amino acids such as valine, leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan, histidine and the like, and glycine, alanine, serine, cysteine, asparagine, glutamine, proline, tyrosine, aspartic acid, Non-essential amino acids such as glutamic acid and arginine can be mentioned, and one or more of these can be used in combination.
 なお、これらのアミノ酸は、無機酸塩(塩酸塩等)、有機酸塩(酢酸塩等)、生体内で加水分解可能なエステル体(メチルエステル等)の形態をなすものであってもよい。 These amino acids may be in the form of inorganic acid salts (such as hydrochlorides), organic acid salts (such as acetates), and in vivo hydrolyzable esters (such as methyl esters).
 さらに、ペプチドとしては、上述したアミノ酸の2つ以上がペプチド結合(アミド結合)を介して重合したものが挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。なお、このようなペプチドは、ジペプチド、トリペプチド、オリゴペプチド(アミノ酸が約10個程度のもの)、ポリペプチド(アミノ酸が数十~数百個のもの)のいずれであってもよい。 Furthermore, as the peptide, one obtained by polymerizing two or more of the above-mentioned amino acids via a peptide bond (amide bond) can be mentioned, and one or two or more of them can be used in combination. Such peptide may be any of dipeptide, tripeptide, oligopeptide (about 10 amino acids) and polypeptide (several tens to hundreds of amino acids).
 なお、このペプチドは、コラーゲンを除くたんぱく質に低分子化処理を施したものを用いることができ、例えば、大豆ペプチド、カゼインペプチド、乳清ペプチド等も挙げられる。 In addition, as this peptide, one obtained by subjecting a protein except collagen to a molecular weight reduction treatment can be used, and examples thereof include soy peptide, casein peptide, whey peptide and the like.
 なお、たんぱく質、アミノ酸、ペプチドは、フレーバー等から由来するものであっても良い。 The protein, amino acid and peptide may be derived from a flavor or the like.
 脂質は、高効率にエネルギー源となる栄養素(三大栄養素)として、高カロリー栄養組成物に含まれる。 Lipids are included in the high-calorie nutrition composition as nutrients (three major nutrients) that are highly efficient energy sources.
 高カロリー栄養組成物中における、脂質の含有量は、高カロリー栄養組成物100mL中、好ましくは8.0g以上30.0g以下程度、より好ましくは8.8g以上25.0g以下程度に設定される。これにより、三大栄養素をバランスよく取得することができるとともに、高カロリー栄養組成物の熱量を2.5kcal/mL以上4.5kcal/mL以下に設定できることから、高カロリー栄養組成物の少量(100mL)の摂取すなわち、包装体1に充填された高カロリー栄養組成物の摂取によって、エネルギーを十分に補給することができる。高カロリー栄養組成物中の脂質の含有量が前記下限値未満の場合、脂質の種類によっては、皮膚の機能が低下するおそれがある。脂質の含有量が前記上限値を超えると、脂質の供給が過剰となり、脂質の種類によっては、肥満を誘発する可能性がある。 The content of the lipid in the high calorie nutritional composition is set to preferably about 8.0 g or more and 30.0 g or less, more preferably about 8.8 g or more and 25.0 g or less in 100 mL of the high calorie nutrient composition . As a result, the three major nutrients can be obtained in a well-balanced manner, and the amount of heat of the high-calorie nutrition composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less. Energy), that is, the intake of the high-calorie nutritional composition filled in the package 1. If the content of lipids in the high-calorie nutrition composition is less than the above lower limit value, depending on the type of lipids, the function of the skin may be reduced. If the content of lipids exceeds the upper limit, the supply of lipids becomes excessive, and depending on the type of lipids, obesity may be induced.
 脂質としては、ヒトが摂取可能なものであれば特に限定されず、例えば、飽和脂肪酸、不飽和脂肪酸、植物油、動物性油脂等が挙げられる。 The lipid is not particularly limited as long as it can be ingested by humans, and examples thereof include saturated fatty acids, unsaturated fatty acids, vegetable oils, animal fats and oils, and the like.
 飽和脂肪酸としては、例えば、カプリル酸、カプリン酸、ラウリン酸、パルミチン酸、ステアリン酸等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Examples of saturated fatty acids include caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid and the like, and one or more of these can be used in combination.
 不飽和脂肪酸としては、例えば、オレイン酸、パルミトレイン酸、リノール酸、アラキドン酸、α-リノレン酸等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Examples of unsaturated fatty acids include oleic acid, palmitoleic acid, linoleic acid, arachidonic acid, α-linolenic acid and the like, and one or more of these can be used in combination.
 植物油としては、例えば、ココナッツオイル、コーン油、綿実油、オリーブオイル、パーム油、パーム核油、ピーナッツ油、菜種油、サフラワー油(紅花油)、ごま油、大豆油、ヒマワリ油、アーモンド油、カシュー油、ヘーゼルナッツ油、マカダミアナッツ油、モンゴンゴ油、ペカン油、松の実油、ピスタチオ油、クルミ油、ヒョウタン実油、バッファローカボチャ油、カボチャ実油、スイカ実油、アマランサスオイル、あんず油、リンゴ油、アルガンオイル、アボカド油、ババスオイル、モリンガ油、ボルネオ脂、ケープ栗油、ココアバター、キャロブオイル、コフネヤシ油、コリアンダー種油、ディカ油、アマニ油、グレープシードオイル、ヘンプオイル、カポック実油、ラッレマンチアオイル、マルーラ油、メドウフォーム油、カラシ油、ナツメグバター、オクラ油、パパイヤ油、シソ油、ペクイ油、ケシ油、プルーン油、キヌア油、ニガー種子油、こめ油、Royle油、サッチャインチオイル、ツバキ油、アザミ油、トマト油、コムギ油、エゴマ油、胚芽油、ヤシ油、落花生油等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Examples of vegetable oils include coconut oil, corn oil, cottonseed oil, olive oil, palm oil, palm kernel oil, peanut oil, rapeseed oil, safflower oil (safflower oil), sesame oil, soybean oil, soybean oil, sunflower oil, almond oil, cashew oil , Hazelnut oil, macadamia oil, mongongo oil, pecan oil, pineseed oil, pistachio oil, walnut oil, gouto nut oil, buffalo pumpkin oil, pumpkin seed oil, watermelon seed oil, amaranth oil, apricot oil, apple oil, Argan oil, avocado oil, babassu oil, moringa oil, borneo oil, cape chestnut oil, cocoa butter, carob oil, kono palm oil, coriander seed oil, dika oil, linseed oil, grape seed oil, hemp oil, kapok real oil, Lelleman Chia oil, Marula oil, meadow foam oil, mosquito oil Chisel oil, nutmeg butter, okra oil, papaya oil, perilla oil, peque oil, poppy oil, poppy oil, prune oil, quinoa oil, niger seed oil, rice oil, Royle oil, satcha inch oil, camellia oil, thistle oil, tomato oil, Wheat oil, sesame oil, germ oil, coconut oil, peanut oil and the like can be mentioned, and one or more of these can be used in combination.
 動物性油脂としては、例えば、ラード(豚脂)、ヘット(牛脂)等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 As animal-derived fats and oils, for example, lard (pork fat), het (cow beef) and the like can be mentioned, and one or more of these can be used in combination.
 なお、脂質は、単独で用いても、2種以上を混合して用いてもよい。また、脂質は、フレーバー等から由来するものであっても良い。 The lipids may be used alone or in combination of two or more. Also, the lipid may be derived from a flavor or the like.
 炭水化物は、単糖を供給するための栄養素(三大栄養素)として、高カロリー栄養組成物に含まれる。 Carbohydrate is included in the high calorie nutrient composition as a nutrient (three major nutrients) for supplying monosaccharides.
 高カロリー栄養組成物中における、炭水化物の含有量は、高カロリー栄養組成物100mL中、好ましくは25.0g以上40.0g以下程度、より好ましくは32.0g以上38.0g以下程度に設定される。これにより、三大栄養素をバランスよく取得することができるとともに、高カロリー栄養組成物の熱量を2.5kcal/mL以上4.5kcal/mL以下に設定できることから、高カロリー栄養組成物の少量(100mL)の摂取、すなわち、包装体1に充填された高カロリー栄養組成物の摂取によって、エネルギーを十分に補給することができる。高カロリー栄養組成物中の炭水化物の含有量が前記下限値未満の場合、炭水化物の種類によっては、十分な熱量が得られないおそれがある。炭水化物の含有量が前記上限値を超えると、炭水化物の供給が過剰となり、炭水化物の種類によっては、糖尿病を誘発する可能性がある。 The content of the carbohydrate in the high calorie nutritional composition is set to preferably about 25.0 g or more and 40.0 g or less, more preferably about 32.0 g or more and 38.0 g or less in 100 mL of the high calorie nutrient composition . As a result, the three major nutrients can be obtained in a well-balanced manner, and the amount of heat of the high-calorie nutrition composition can be set to 2.5 kcal / mL or more and 4.5 kcal / mL or less. Energy), that is, the intake of the high-calorie nutritional composition filled in the package 1. If the content of carbohydrates in the high calorie nutritional composition is less than the above lower limit, depending on the type of carbohydrates, a sufficient amount of heat may not be obtained. When the content of carbohydrates exceeds the upper limit, the supply of carbohydrates becomes excessive, and depending on the type of carbohydrates, diabetes may be induced.
 炭水化物としては、生体に吸収されてカロリー源(エネルギー源)になるものであれば特に限定はなく、例えば、単糖、二糖、および多糖が挙げられる。 The carbohydrate is not particularly limited as long as it is absorbed by a living body and becomes a calorie source (energy source), and examples thereof include monosaccharides, disaccharides, and polysaccharides.
 単糖としては、例えば、グルコース(ブドウ糖)、フルクトース(果糖)、ガラクトース等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Examples of monosaccharides include glucose (glucose), fructose (fructose), galactose and the like, and one or more of these can be used in combination.
 二糖としては、例えば、スクロース(ショ糖)、ラクトース(乳糖)、マルトース(麦芽糖)、イソマルトース、トレハロース等が挙げられる。 Examples of disaccharides include sucrose (sucrose), lactose (lactose), maltose (malt), isomaltose, trehalose and the like.
 多糖の具体例としては、デンプン(アミロース、アミロペクチン)、デキストリン等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができるが、中でも、デキストリンであることが好ましい。 Specific examples of the polysaccharide include starch (amylose, amylopectin), dextrin and the like, and one or more of them may be used in combination, and among them, dextrin is preferable.
 デキストリンは、数個のα-グルコースがグリコシド結合によって重合した物質の総称であり、デンプンを加水分解して得ることができる。デキストリンは、小腸内での分解速度が遅く吸収が緩やかであることから、急激な血糖上昇を防止しうる。また、デキストリンを用いることにより、高カロリー栄養組成物の浸透圧を低減することができ、浸透圧性の下痢を予防しうる。デキストリンとしては、α-グルコースの重合度が高い高分子デキストリン、およびα-グルコースの重合度が低い低分子デキストリンのいずれを用いてもよいが、より浸透圧を低減可能な高分子デキストリンを用いることが好ましい。なお、低分子デキストリンは、マルトデキストリンとも呼ばれ、通常、3~5個のα-グルコースが重合したものである。 Dextrin is a generic term for substances in which several α-glucoses are polymerized by glycosidic bonds, and can be obtained by hydrolyzing starch. Dextrin can prevent a rapid rise in blood glucose, because the rate of degradation in the small intestine is slow and absorption is slow. In addition, by using dextrin, the osmotic pressure of the high-calorie nutrition composition can be reduced, and osmotic diarrhea can be prevented. As the dextrin, any of high molecular weight dextrin with high degree of polymerization of α-glucose and low molecular weight dextrin with low degree of polymerization of α-glucose may be used, but high molecular weight dextrin capable of reducing the osmotic pressure can be used Is preferred. The low molecular weight dextrin is also called maltodextrin, and is usually obtained by polymerizing 3 to 5 α-glucoses.
 このデキストリンは、自ら調製しても、市販品を用いてもよい。デキストリンを調製する場合には、公知のデンプン、例えば、トウモロコシ、ワキシーコーン、小麦、米、ワキシーライス、ワキシーミロ、豆(ソラマメ、緑豆、小豆等)、馬鈴薯、甘藷、タピオカ等に含有されるデンプンを、公知の方法により加水分解することで調製することができる。一方、市販されたデキストリンとしては、例えば、TK-16(松谷化学工業株式会社製)、サンデック♯300(三和澱粉工業株式会社製)、サンデック♯250(三和澱粉工業株式会社製)、サンデック♯150(三和澱粉工業株式会社製)等が挙げられる。 The dextrin may be prepared by itself or a commercially available product may be used. In the case of preparing dextrin, starch contained in known starches such as corn, waxy corn, wheat, rice, waxy rice, waxy milo, beans (eg broad bean, green bean, azuki bean), potato, sweet potato, tapioca etc. It can be prepared by hydrolysis according to known methods. On the other hand, as commercially available dextrin, for example, TK-16 (made by Matsutani Chemical Industry Co., Ltd.), Sandeck # 300 (made by Sanwa Starch Industry Co., Ltd.), Sandeck # 250 (made by Sanwa Starch Industry Co., Ltd.), Sandeck # 150 (manufactured by Sanwa Starch Co., Ltd.) and the like.
 上述の炭水化物は、単独で用いても、2種以上を混合して用いてもよい。また、炭水化物は、フレーバー等から由来するものであっても良い。 The above-mentioned carbohydrates may be used alone or in combination of two or more. Also, the carbohydrate may be derived from a flavor or the like.
 また、このような炭水化物において、本発明では、重合度が低い低分子の炭水化物、すなわち、単糖、二糖、または、低分子デキストリンのような低分子化多糖を含むことが好ましい。これにより、高カロリー栄養組成物における、炭水化物の相溶性が高くなることから、高カロリー栄養組成物中での炭水化物の含有量を前記範囲のように高くしたとしても、高カロリー栄養組成物中に炭水化物を溶かし合わせることができる。そのため、高カロリー栄養組成物中における、炭水化物の凝集物や沈殿物の発生が的確に抑制または防止され、高カロリー栄養組成物を、炭水化物が均一に分散されたものとすることができる。 Further, among such carbohydrates, in the present invention, it is preferable to include low molecular weight carbohydrates having a low degree of polymerization, that is, monosaccharides, disaccharides, or low molecular weight polysaccharides such as low molecular weight dextrins. As a result, the compatibility of the carbohydrates in the high calorie nutritional composition becomes high, and therefore, even if the content of the carbohydrate in the high calorie nutritional composition is increased as in the above range, the high calorie nutritional composition contains It can dissolve carbohydrates together. Therefore, the occurrence of carbohydrate agglomerates and precipitates in the high calorie nutritional composition can be properly suppressed or prevented, and the high calorie nutritional composition can be one in which carbohydrates are uniformly dispersed.
 高カロリー栄養組成物は、前述した、たんぱく質、脂質および炭水化物の栄養素(三大栄養素)の他、栄養素としてビタミンを含有していてもよい。 The high-calorie nutrition composition may contain vitamins as nutrients in addition to the protein, lipid and carbohydrate nutrients (major nutrient) described above.
 ビタミンとしては、特に限定されず、ビタミンA、ビタミンD、ビタミンE、ビタミンK、ビタミンB1、ビタミンB2、ナイアシン、パントテン酸、ビタミンB6、ビオチン、葉酸、ビタミンB12、ビタミンC、カルニチンのような各種ビタミンが挙げられ、これらを単独で用いても良いし、2種以上を混合して用いることもできる。 The vitamin is not particularly limited, and various types such as vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacin, pantothenic acid, vitamin B6, biotin, folic acid, vitamin B12, vitamin C, carnitine Vitamins may be mentioned, and these may be used alone or in combination of two or more.
 なお、高カロリー栄養組成物100mLあたりの各種ビタミンの好ましい含有量は以下の通りである。 In addition, preferable content of the various vitamins per 100 mL of high calorie nutrition composition is as follows.
 ビタミンA:好ましくは0~3000μg、より好ましくは20~250μg
 ビタミンD:好ましくは0.1~50μg、より好ましくは0.1~5.0μg
 ビタミンE:好ましくは0.2~800mg、より好ましくは0.2~5.0mg
 ビタミンK:好ましくは0.5~1000μg、より好ましくは2~50μg
 ビタミンB1:好ましくは0.01~10mg、より好ましくは0.1~3.0mg
 ビタミンB2:好ましくは0.01~10mg、より好ましくは0.05~3.0mg
 ナイアシン:好ましくは0.1~30mgNE、より好ましくは0.5~6mgNE
 パントテン酸:好ましくは0.1~5.5mg、より好ましくは0.2~3.0mg
 ビタミンB6:好ましくは0.01~6.0mg、より好ましくは0.1~3.0mg
 ビオチン:好ましくは0.1~100μg、より好ましくは1~20μg
 葉酸:好ましくは1~1000μg、より好ましくは10~100μg
 ビタミンB12:好ましくは0.01~10μg、より好ましくは0.2~3.0μg
 ビタミンC:好ましくは1~200mg、より好ましくは5~100mg
 カルニチン:好ましくは1~300mg、より好ましくは10~70mg
Vitamin A: preferably 0 to 3000 μg, more preferably 20 to 250 μg
Vitamin D: preferably 0.1 to 50 μg, more preferably 0.1 to 5.0 μg
Vitamin E: preferably 0.2 to 800 mg, more preferably 0.2 to 5.0 mg
Vitamin K: preferably 0.5 to 1000 μg, more preferably 2 to 50 μg
Vitamin B1: preferably 0.01 to 10 mg, more preferably 0.1 to 3.0 mg
Vitamin B2: preferably 0.01 to 10 mg, more preferably 0.05 to 3.0 mg
Niacin: preferably 0.1 to 30 mg NE, more preferably 0.5 to 6 mg NE
Pantothenic acid: preferably 0.1 to 5.5 mg, more preferably 0.2 to 3.0 mg
Vitamin B 6: preferably 0.01 to 6.0 mg, more preferably 0.1 to 3.0 mg
Biotin: preferably 0.1 to 100 μg, more preferably 1 to 20 μg
Folic acid: preferably 1 to 1000 μg, more preferably 10 to 100 μg
Vitamin B12: preferably 0.01 to 10 μg, more preferably 0.2 to 3.0 μg
Vitamin C: preferably 1 to 200 mg, more preferably 5 to 100 mg
Carnitine: preferably 1 to 300 mg, more preferably 10 to 70 mg
 なお、各種ビタミンの好ましい範囲およびより好ましい範囲の下限値および上限値は、それぞれの数値を含むこととする。 The lower limit value and the upper limit value of the preferable range and the more preferable range of various vitamins are assumed to include the respective numerical values.
 また、高カロリー栄養組成物は、前述した、たんぱく質、脂質および炭水化物の栄養素(三大栄養素)の他、栄養素としてミネラルを含有していてもよい。 In addition to the protein, lipid and carbohydrate nutrients (major nutrient) described above, the high calorie nutrient composition may also contain minerals as nutrients.
 ミネラルとしては、特に限定されず、例えば、ナトリウム、カリウム、カルシウム、リン、マグネシウムのような各種ミネラルが挙げられ、これらを単独で用いても良いし、2種以上を混合して用いることもできる。 The minerals are not particularly limited, and include, for example, various minerals such as sodium, potassium, calcium, phosphorus and magnesium, which may be used alone or in combination of two or more. .
 なお、高カロリー栄養組成物100mLあたりの各種ミネラルの好ましい含有量は以下の通りである。 In addition, preferable content of the various minerals per 100 mL of high calorie nutrient composition is as follows.
 ナトリウム:好ましくは50~300mg、より好ましくは100~190mg
 カルシウム:好ましくは10~200mg、より好ましくは30~100mg
 リン:好ましくは1~350mg、より好ましくは25~150mg
 マグネシウム:好ましくは1~75mg、より好ましくは10~50mg
 カリウム:好ましくは1~350mg、より好ましくは25~180mg
Sodium: preferably 50 to 300 mg, more preferably 100 to 190 mg
Calcium: preferably 10 to 200 mg, more preferably 30 to 100 mg
Phosphorus: preferably 1 to 350 mg, more preferably 25 to 150 mg
Magnesium: preferably 1 to 75 mg, more preferably 10 to 50 mg
Potassium: preferably 1 to 350 mg, more preferably 25 to 180 mg
 なお、各種ミネラルの好ましい範囲およびより好ましい範囲の下限値および上限値は、それぞれの数値を含むこととする。 The lower limit value and the upper limit value of the preferable range and the more preferable range of the various minerals include their respective numerical values.
 さらに、高カロリー栄養組成物は、前述した、たんぱく質、脂質および炭水化物の栄養素(三大栄養素)の他、栄養素として微量元素を含有していてもよい。 Furthermore, the high-calorie nutrition composition may contain trace elements as nutrients in addition to the aforementioned protein, lipid and carbohydrate nutrients (three major nutrients).
 微量元素としては、特に限定されず、例えば、鉄、亜鉛、銅、塩素、ヨウ素、マンガン、セレン、クロム、モリブデンのような各種微量元素が挙げられ、これらを単独で用いても良いし、2種以上を混合して用いることもできる。 The trace elements are not particularly limited, and include, for example, various trace elements such as iron, zinc, copper, chlorine, iodine, manganese, selenium, chromium and molybdenum, which may be used alone, 2 It is also possible to use a mixture of species and more.
 なお、高カロリー栄養組成物100mLあたりの各種微量元素の好ましい含有量は以下の通りである。 In addition, preferable content of various trace elements per 100 mL of the high calorie nutrient composition is as follows.
 鉄:好ましくは0.1~55mg、より好ましくは1~10mg
 銅:好ましくは0.01~1.0mg、より好ましくは0.06~0.6mg
 塩素:好ましくは1~350mg、より好ましくは25~180mg
 ヨウ素:好ましくは0.1~1000μg、より好ましくは1~100μg
 マンガン:好ましくは0.01~10mg、より好ましくは0.1~2.0mg
 セレン:好ましくは0.1~450μg、より好ましくは1~35μg
 亜鉛:好ましくは0.1~20mg、より好ましくは1~10mg
 クロム:好ましくは0.1~30μg、より好ましくは1~20μg
 モリブデン:好ましくは0.1~30μg、より好ましくは1~20μg
Iron: preferably 0.1 to 55 mg, more preferably 1 to 10 mg
Copper: preferably 0.01 to 1.0 mg, more preferably 0.06 to 0.6 mg
Chlorine: preferably 1 to 350 mg, more preferably 25 to 180 mg
Iodine: preferably 0.1 to 1000 μg, more preferably 1 to 100 μg
Manganese: preferably 0.01 to 10 mg, more preferably 0.1 to 2.0 mg
Selenium: preferably 0.1 to 450 μg, more preferably 1 to 35 μg
Zinc: preferably 0.1 to 20 mg, more preferably 1 to 10 mg
Chromium: preferably 0.1 to 30 μg, more preferably 1 to 20 μg
Molybdenum: preferably 0.1 to 30 μg, more preferably 1 to 20 μg
 なお、各種微量元素の好ましい範囲およびより好ましい範囲の下限値および上限値は、それぞれの数値を含むこととする。 The lower limit value and the upper limit value of the preferable range and the more preferable range of each of the various trace elements are assumed to include the respective numerical values.
 以上のような栄養素を含む高カロリー栄養組成物は、その熱量が2.5kcal/mL以上4.5kcal/mL以下であればよいが、3.0kcal/mL以上4.3kcal/mL以下であることが好ましく、3.5kcal/mL以上4.1kcal/mL以下であることがより好ましい。高カロリー栄養組成物中の熱量が2.5kcal/mL未満の場合、小容量で高熱量が摂取できない。高カロリー栄養組成物中の熱量が4.5kcal/mLを超えると、栄養素が溶解することが困難である。これにより、高カロリー栄養組成物の少量(具体的には、100mL)の摂取によっても、エネルギーを十分に補給することができる。すなわち、食欲が低下していたり、嚥下障害を伴う高齢者が、病院や介護施設等において、看護師や介護士等の第三者の監督下で、1食に取得できる高カロリー栄養組成物(流動食)の総量は、一般的に、100mL程度と言われる。そのため、容器10内に100mL充填される高カロリー栄養組成物の熱量を前記範囲内に設定し、さらに、朝食、昼食および夕食の三食に、包装体1から高カロリー栄養組成物を取得することで、750kcal以上1350kcal以下、好ましくは900kcal以上1290kcal以下、より好ましくは1050kcal以上1230kcal以下のエネルギーを取得することができる。そのため、高カロリー栄養組成物の三食の摂取により、高齢者が1日で取得することが望ましいエネルギー量を満足することができる。 The calorie content of the high-calorie nutritional composition containing the above-mentioned nutrients may be 2.5 kcal / mL or more and 4.5 kcal / mL or less, but 3.0 kcal / mL or more and 4.3 kcal / mL or less Is preferred, and more preferably 3.5 kcal / mL or more and 4.1 kcal / mL or less. If the amount of heat in the high-calorie nutrition composition is less than 2.5 kcal / mL, a small amount of high-heat can not be consumed. When the amount of heat in the high calorie nutritional composition exceeds 4.5 kcal / mL, it is difficult for the nutrients to dissolve. Thereby, energy can be sufficiently replenished even by the intake of a small amount (specifically, 100 mL) of the high-calorie nutrition composition. That is, a high-calorie nutritional composition (for which elderly people with poor appetite or with dysphagia can obtain one meal under supervision of a third party such as a nurse or carer at a hospital or nursing facility etc.) The total amount of liquid food is generally said to be about 100 mL. Therefore, set the heat quantity of the high-calorie nutrition composition filled in 100 mL in the container 10 within the above range, and further obtain the high-calorie nutrition composition from the package 1 at breakfast, lunch and dinner three meals. Energy of 750 kcal or more and 1350 kcal or less, preferably 900 kcal or more and 1290 kcal or less, more preferably 1050 kcal or more and 1230 kcal or less can be obtained. Therefore, the intake of three meals of the high-calorie nutrition composition can satisfy the amount of energy which the elderly person wants to obtain in one day.
 また、高カロリー栄養組成物は、本発明では、その25℃での粘度が3,500mPa・s以上17,500mPa・s以下であればよいが、5,000mPa・s以上15,000mPa・s以下であることが好ましい。高カロリー栄養組成物中の粘度が前記下限値未満の場合、逆流性肺炎や下痢を誘発する可能性がある。高カロリー栄養組成物中の粘度が前記上限値を超えると、摂取時にべたつく可能性がある。前記粘度をかかる範囲内に設定することで、高カロリー栄養組成物の粘度を、流動食に適した範囲内に設定することができる。そのため、この高カロリー栄養組成物を、食欲が低下していたり、嚥下障害を伴う高齢者が摂取する場合であったとしても、経口により容易に高カロリー栄養組成物を取得する(食する)ことができる。また、後述する容器10が備える開口部20(供給部)を介して、液だれを生じさせることなく、容器本体30の押圧により、高カロリー栄養組成物を容器本体30から容易に排出させて、経口により高カロリー栄養組成物を摂取者が取得する(食する)ことができる。さらに、高カロリー栄養組成物中において、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散させることができ、安定化が図られた高カロリー栄養組成物とすることができる。 In the present invention, the high-calorie nutrition composition may have a viscosity of 3,500 mPa · s or more and 17,500 mPa · s or less at 25 ° C., but 5,000 mPa · s or more and 15,000 mPa · s or less Is preferred. If the viscosity in the high calorie nutritional composition is less than the lower limit, reflux pneumonia or diarrhea may be induced. If the viscosity in the high calorie nutritional composition exceeds the above upper limit, it may become sticky at the time of intake. By setting the viscosity within the above range, the viscosity of the high calorie nutrient composition can be set within the range suitable for liquid food. Therefore, even if the high calorie nutritional composition is consumed by an elderly person with decreased appetite or swallowing dysphagia, the high calorie nutritional composition can be easily obtained orally (eating). Can. In addition, the high-calorie nutrition composition can be easily discharged from the container body 30 by pressing of the container body 30 without causing liquid dripping through the opening 20 (supply unit) provided in the container 10 described later. By the oral route, the user can obtain (eat) the high-calorie nutrition composition. Furthermore, in a high calorie nutritional composition, a protein, lipid and carbohydrate as major nutrients can be dispersed without separation with excellent stability, and a stabilized high calorie nutritional composition is provided. Can.
 また、高カロリー栄養組成物は、前述した三大栄養素を含む栄養素の他に、乳化剤を含有することが好ましい。 Moreover, it is preferable that a high calorie nutrient composition contains an emulsifier in addition to the nutrient containing the three major nutrients mentioned above.
 これにより、高カロリー栄養組成物における、たんぱく質と脂質と炭水化物との相溶性がより高くなる。そのため、高カロリー栄養組成物中でのたんぱく質、脂質および炭水化物の含有量を、それぞれ、前記範囲のように高くしたとしても、高カロリー栄養組成物中に、たんぱく質と脂質と炭水化物とを溶かし合わせることができる。したがって、高カロリー栄養組成物を、たんぱく質、脂質および炭水化物が均一に分散・乳化されたものとすることができる。 This results in higher compatibility of proteins, lipids and carbohydrates in high calorie nutritional compositions. Therefore, even if the content of protein, lipid and carbohydrate in the high-calorie nutritional composition is increased as in the above range, respectively, the protein, lipid and carbohydrate are dissolved and combined in the high-calorie nutritional composition. Can. Therefore, the high-calorie nutrition composition can be one in which proteins, lipids and carbohydrates are uniformly dispersed and emulsified.
 この乳化剤としては、特に限定されないが、例えば、有機酸モノグリセライド、ポリグリセリンエステル、ショ糖脂肪酸エステル、ソルビタン脂肪酸エステル、プロピレングリコール脂肪酸エステルのような脂肪酸エステル、ポリソルベート、ポリグリセリン縮合リシノレート、ジアシルグリセロール、ワックス類、ステロールエステル類、リン脂質等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。中でも、有機酸モノグリセライドとポリグリセリンエステルとのうちの一方を含むことが好ましく、これらの双方を含むことがより好ましい。また、乳化剤として有機酸モノグリセライドとポリグリセリンエステルとの双方を含む場合、これらの含有量は、それぞれ、高カロリー栄養組成物中において、有機酸モノグリセライドが好ましくは0.5g/100mL以上1.5g/100mL以下、より好ましくは1.3g/100mL程度に設定され、ポリグリセリンエステルが好ましくは0.3g/100mL以上0.8g/100mL以下、より好ましくは0.7g/100mL程度に設定される。乳化剤として前記のものを選択し、さらに、その含有量を前記のように設定することで、前記効果をより顕著に発揮させることができる。また、高カロリー栄養組成物中の有機酸モノグリセライドが0.5g/100mL未満の場合、高カロリー栄養組成物に含まれる栄養素の種類によっては、乳化系が安定せずに、水層と油層が分離するおそれがある。高カロリー栄養組成物中の有機酸モノグリセライドが1.5g/100mLを超えると、高カロリー栄養組成物に含まれる栄養素の種類によっては、過剰な有機酸モノグリセライドによって乳化系が崩壊する可能性がある。高カロリー栄養組成物中のポリグリセリンエステルが0.3g/100mL未満の場合、高カロリー栄養組成物に含まれる栄養素の種類によっては、乳化系が安定せずに、水層と油層が分離するおそれがある。高カロリー栄養組成物中の有機酸モノグリセライドが0.8g/100mLを超えると、高カロリー栄養組成物に含まれる栄養素の種類によっては、過剰な有機酸モノグリセライドによって乳化系が崩壊する可能性がある。 The emulsifier is not particularly limited. For example, organic acid monoglyceride, polyglycerin ester, sucrose fatty acid ester, sorbitan fatty acid ester, fatty acid ester such as propylene glycol fatty acid ester, polysorbate, polyglycerin condensed ricinolate, diacylglycerol, wax And sterol esters, phospholipids and the like, and one or more of these may be used in combination. Among them, it is preferable to include one of the organic acid monoglyceride and the polyglycerin ester, and it is more preferable to include both of them. In addition, when both organic acid monoglyceride and polyglycerin ester are contained as an emulsifying agent, the content thereof is preferably 0.5 g / 100 mL or more and 1.5 g / l or more of the organic acid monoglyceride in the high calorie nutritional composition. It is set to 100 mL or less, more preferably about 1.3 g / 100 mL, and the polyglycerin ester is preferably set to 0.3 g / 100 mL or more and 0.8 g / 100 mL or less, more preferably about 0.7 g / 100 mL. By selecting the above-described one as the emulsifying agent and setting the content as described above, the above-mentioned effect can be more remarkably exhibited. In addition, when the organic acid monoglyceride in the high calorie nutritional composition is less than 0.5 g / 100 mL, depending on the type of nutrient contained in the high calorie nutritional composition, the emulsifying system is not stable and the water layer and the oil layer are separated. There is a risk of When the amount of organic acid monoglyceride in the high calorie nutritional composition exceeds 1.5 g / 100 mL, the emulsion system may be broken by excess organic acid monoglyceride depending on the type of nutrient contained in the high calorie nutritional composition. When the amount of polyglycerin ester in the high calorie nutritional composition is less than 0.3 g / 100 mL, depending on the types of nutrients contained in the high calorie nutritional composition, the emulsion system may not be stabilized and the water layer and the oil layer may separate. There is. When the amount of organic acid monoglyceride in the high calorie nutritional composition exceeds 0.8 g / 100 mL, the emulsion system may be broken by excess organic acid monoglyceride depending on the types of nutrients contained in the high calorie nutritional composition.
 また、有機酸モノグリセライドとしては、特に限定されず、例えば、市販のものを用いることができ、具体的には、ポエムW-60(理研ビタミン株式会社製)、ポエムG-002(理研ビタミン株式会社製)、ポエムB-10(理研ビタミン株式会社製)等が挙げられる。さらに、ポリグリセリンエステルとしても、特に限定されず、例えば、市販のものを用いることができ、具体的には、ポエムJ-0381V(理研ビタミン株式会社製)、ポエムJ-0281V(理研ビタミン株式会社製)等が挙げられる。 The organic acid monoglyceride is not particularly limited. For example, a commercially available product can be used. Specifically, Poem W-60 (manufactured by Riken Vitamin Co., Ltd.), Poem G-002 (Riken Vitamin Co., Ltd.) And Poem B-10 (manufactured by Riken Vitamin Co., Ltd.). Furthermore, the polyglycerin ester is not particularly limited and, for example, commercially available products can be used. Specifically, Poem J-0381 V (manufactured by Riken Vitamin Co., Ltd.), Poem J J 0281 V (Riken Vitamin Co., Ltd.) And the like.
 また、高カロリー栄養組成物は、前述した三大栄養素を含む栄養素の他に、発酵乳を含有することが好ましい。 Moreover, it is preferable that a high-calorie nutrition composition contains fermented milk other than the nutrient which contains the three main nutrients mentioned above.
 ここで、高カロリー栄養組成物は、たんぱく質、脂質および炭水化物の栄養素を前述した含有量のように高濃度に含まれることが好ましいこと、また、たんぱく質および炭水化物の栄養素を前述したように低分子化することが好ましいこと等に起因して、独特の臭み、えぐ味や苦味等有するものとなる傾向を有する。 Here, it is preferable that the high-calorie nutrition composition contains protein, lipid and carbohydrate nutrients at a high concentration as described above, and that the protein and carbohydrate nutrients are reduced as described above. Due to the fact that it is preferable, etc., it has a tendency to have unique odor, great taste, bitterness and the like.
 このような高カロリー栄養組成物を、発酵乳を含有するものとすることで、独特の臭みや、えぐ味、苦味等の不快に感じる風味を低減させることができる。そのため、この高カロリー栄養組成物を食する摂取者の食欲の向上が図られる。 By using such a high-calorie nutrition composition to contain fermented milk, it is possible to reduce the offensive flavor such as unique smell, bitter taste and so on. Therefore, the improvement of the appetite of the user who eats this high-calorie nutrition composition is achieved.
 また、高カロリー栄養組成における、発酵乳の含有量は、好ましくは1.0g/100mL以上3.0g/100mL以下、より好ましくは1.3g/100mL以上1.8g/100mL以下に設定される。高カロリー栄養組成物中の発酵乳が前記下限値未満の場合、高カロリー栄養組成物に含まれる栄養素の種類によっては、苦味が強く感じられ、風味が損なわれるおそれがある。高カロリー栄養組成物中の発酵乳が前記上限値を超えると、高カロリー栄養組成物に含まれる栄養素の種類によっては、甘味と酸味が強く感じられ、風味が損なわれるおそれがある。発酵乳の含有量を前記範囲内に設定することにより、前記効果をより顕著に発揮させることができる。 In addition, the content of fermented milk in the high calorie nutrient composition is preferably set to 1.0 g / 100 mL or more and 3.0 g / 100 mL or less, more preferably 1.3 g / 100 mL or more and 1.8 g / 100 mL or less. When the fermented milk in the high-calorie nutrition composition is less than the above lower limit, depending on the type of nutrients contained in the high-calorie nutrition composition, bitter taste may be felt strongly and flavor may be lost. When the fermented milk in the high-calorie nutrition composition exceeds the upper limit, sweetness and sourness may be felt strongly depending on the kind of nutrients contained in the high-calorie nutrition composition, and the flavor may be impaired. By setting the content of the fermented milk within the above range, the above-mentioned effect can be more remarkably exhibited.
 なお、本明細書中において、発酵乳とは、乳またはこれと同等以上の無脂乳固形分を含むもの等が、乳酸菌や酵母等の微生物により乳酸を産生して発酵したもののことを言う。したがって、発酵乳は、乳またはこれと同等以上の無脂乳固形分を含むものに由来して発酵したものであれば、特に限定されず、例えば、市販のヨーグルトの他、ハネピスJP-J(大洋香料株式会社製)、発酵乳FM-J(大洋香料株式会社製)、無糖発酵乳ベース(協同乳業株式会社製)、加糖発酵乳液(協同乳業株式会社製)等が挙げられる。 In addition, in this specification, fermented milk means what the thing containing the non-fat milk solid content more than milk or this equivalent produces and ferments lactic acid by microorganisms, such as lactic acid bacteria and yeast. Therefore, the fermented milk is not particularly limited as long as it is fermented from milk or one containing non-fat milk solids equal to or more than this, and is not particularly limited. For example, other than commercially available yogurt, Honeypis JP-J ( Taiyo Fragrance Co., Ltd. made, Fermented milk FM-J (made by Taiyo Fragrance Co., Ltd.), sugar-free fermented milk base (made by Kyodo Dairy Co., Ltd.), sweetened fermented milk solution (made by Kyodo Dairy Co., Ltd.), etc.
 さらに、高カロリー栄養組成物は、フレーバーを含有していてもよい。
 これにより、高カロリー栄養組成物のさらなる風味の向上が図られるため、この高カロリー栄養組成物を食する摂取者の食欲がより向上する。
Additionally, the high calorie nutritional composition may contain a flavor.
As a result, the flavor of the high-calorie nutrition composition is further improved, and the appetite of the user who eats the high-calorie nutrition composition is further improved.
 なお、本明細書中において、「フレーバー」とは、高カロリー栄養組成物に香りや味を付与するために加えるものを言い、一般的に「フレーバー」として販売されているものや、「エキス」「粉末調味料」「粉末香料」「液体香料」として販売されているもの等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 In the present specification, "flavor" means something added to a high calorie nutritional composition to impart a flavor or taste, and is generally sold as "flavor" or "extract". What is marketed as "powder seasoning", "powder flavor", "liquid flavor" etc. are mentioned, It can be used combining 1 type, or 2 or more types in these.
 また、高カロリー栄養組成物中における、フレーバーの含有量は、高カロリー栄養組成物100mL中、好ましくは0.1g以上3.5g以下程度、より好ましくは0.4g以上3.0g以下程度に設定される。これにより、高カロリー栄養組成物にフレーバーを添加することにより得られる効果をより顕著に発揮させることができる。 In addition, the content of the flavor in the high-calorie nutrition composition is preferably set to about 0.1 to 3.5 g, more preferably about 0.4 to 3.0 g, in 100 mL of the high-calorie nutrition composition. Be done. Thereby, the effect obtained by adding a flavor to a high calorie nutrient composition can be exhibited more notably.
 高カロリー栄養組成物において、フレーバーの種類としては、特に限定されないが、例えば、トマト風味等の野菜スープ味、アップル風味等の果実ジュース味、ヨーグルト風味、和風だし風味(かつお、こんぶ)、クリームシチュー風味、ビーフシチュー風味、カレー風味、味噌汁風味、豚汁風味、クラムチャウダー風味、または、ラーメン風味(味噌、とんこつ、醤油)のものが挙げられる。なお、フレーバーは、市販のスープの素や粉末スープを用いても良い。 In the high-calorie nutrition composition, the type of flavor is not particularly limited. For example, vegetable soup taste such as tomato flavor, fruit juice taste such as apple flavor, yogurt flavor, Japanese-style miso flavor (bonito, konbu), cream stew Flavor, beef stew flavor, curry flavor, miso soup flavor, pork broth flavor, clam chowder flavor, or ramen flavor (miso, tonkotsu, soy sauce). As the flavor, a commercially available soup base or powdered soup may be used.
 高カロリー栄養組成物は、さらに、機能成分として、ポリグルタミン酸、グルコサミン、フコイダン、コラーゲン、ヒアルロン酸、食物繊維、オリゴ糖等を含有していてもよい。 The high calorie nutrient composition may further contain, as functional components, polyglutamic acid, glucosamine, fucoidan, collagen, hyaluronic acid, dietary fiber, oligosaccharides and the like.
 これらの機能成分は、唾液分泌促進作用、カルシウム吸収促進、保湿作用、ピロリ菌の排除、胃粘膜の保護・修復促進、持久力向上、血漿コレステロールの低下、血糖応答の改善、大腸機能の改善、および大腸がんの予防等の様々な機能を発揮する。 These functional components have a salivary secretion promoting action, calcium absorption promoting action, moisturizing action, elimination of H. pylori bacteria, promotion of protection and repair of gastric mucosa, improvement of endurance, reduction of plasma cholesterol, improvement of blood glucose response, improvement of colon function, And various functions such as prevention of colon cancer.
 食物繊維としては、特に限定されないが、例えば、セルロース、ヘミセルロース、リグニン、不溶性ペクチン、キチン、キトサン、サイリウム種皮、低分子化アルギン酸ナトリウム等の不溶性食物繊維、水溶性ペクチン、グァーガム、コンニャクマンナン、グルコマンナン、アルギン酸、寒天、化学修飾多糖類、ポリデキストロース、難消化性オリゴ糖、マルチトール、イヌリン、カラギーナン、小麦ふすま、難消化性デキストリン(例えば、パインファイバーC(松谷化学工業社製))、グァーガム分解物等の水溶性食物繊維等が挙げられ、単独で用いても、2種以上を混合して用いてもよい。なお、高カロリー栄養組成物における食物繊維の含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 The dietary fiber is not particularly limited, but, for example, cellulose, hemicellulose, lignin, insoluble pectin, chitin, chitosan, pylium seed coat, insoluble dietary fiber such as low molecular weight sodium alginate, water soluble pectin, guar gum, konjac mannan, glucomannan , Alginic acid, agar, chemically modified polysaccharide, polydextrose, resistant oligosaccharide, maltitol, inulin, carrageenan, wheat bran, resistant digestive dextrin (eg, pine fiber C (made by Matsutani Chemical Industry Co., Ltd.)), guar gum decomposition And water soluble dietary fiber, etc., and may be used alone or as a mixture of two or more. In addition, content of the dietary fiber in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
 高カロリー栄養組成物は、さらにその他の公知の成分、例えば、保健機能成分、食品添加物、安定剤等を含有していてもよい。 The high calorie nutritional composition may further contain other known ingredients such as health functional ingredients, food additives, stabilizers and the like.
 保健機能成分とは、摂取することによって生体に対し一定の機能を発揮する成分である。 The health functional component is a component that exerts a certain function on a living body by ingestion.
 このような保険機能成分としては、特に限定されないが、例えば、難消化性オリゴ糖、糖アルコール、クエン酸リンゴ酸カルシウム(CCM)およびカゼインホスホペプチド(CPP)、キトサン、L-アラビノース、グァバ葉ポリフェノール、小麦アルブミン、豆鼓エキス、ジアシルグリセロール、ジアシルグリセロール植物性ステロール、大豆イソフラボン、乳塩基性たんぱく質等が挙げられ、これらのうちの1種または2種以上を組み合わせて用いることができる。 Such insurance functional components include, but are not limited to, for example, nondigestible oligosaccharides, sugar alcohols, calcium citrate malate (CCM) and casein phosphopeptide (CPP), chitosan, L-arabinose, guava leaf polyphenol And wheat albumin, bean paste extract, diacylglycerol, diacylglycerol vegetable sterol, soybean isoflavone, milk basic protein and the like, and one or more of them may be used in combination.
 難消化性オリゴ糖とは、単糖類がグリコシド結合によって結合した化合物のうち、多糖類ほどは分子量が大きくない(300~3000程度)糖類である。 Among the compounds in which monosaccharides are linked by glycosidic bonds, resistant oligosaccharides are saccharides whose molecular weight is not as high as that of polysaccharides (about 300 to 3000).
 なお、この難消化性オリゴ糖は、ヒトの消化酵素では分解されず、ヒトの消化酵素で分解されるものについては、前述した炭水化物に包含される。このような難消化性オリゴ糖を摂取することで、整腸効果が得られる。 The indigestible oligosaccharides are not degraded by human digestive enzymes, and those that are degraded by human digestive enzymes are included in the above-mentioned carbohydrates. By intake of such indigestible oligosaccharides, an intestinal regulation effect can be obtained.
 難消化性オリゴ糖としては、特に限定されないが、例えば、キシロオリゴ糖、フラクトオリゴ糖、大豆オリゴ糖、イソマルトオリゴ糖、乳果オリゴ糖、ラクチュロース、ガラクトオリゴ糖等が挙げられる。これらの難消化性オリゴ糖は、単独で用いても、2種以上を混合して用いてもよい。なお、高カロリー栄養組成物における難消化性オリゴ糖の含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 Examples of indigestible oligosaccharides include, but are not limited to, xylooligosaccharides, fructooligosaccharides, soybean oligosaccharides, isomaltooligosaccharides, milk fruit oligosaccharides, lactulose, galactooligosaccharides and the like. These indigestible oligosaccharides may be used alone or in combination of two or more. In addition, content of the indigestible oligosaccharide in a high calorie nutrition composition is suitably adjusted by the subject etc. who apply a high calorie nutrition composition.
 糖アルコールとは、アルドースやケトースのカルボニル基が還元されて生成する糖の一種であり、小腸から体内への吸収が悪くカロリーになりにくいものである。 Sugar alcohol is a kind of sugar produced by reducing the carbonyl group of aldoses and ketoses, and is a substance that is poorly absorbed from the small intestine into the body and hardly turns into calories.
 この糖アルコールは、口内細菌によって酸に代謝されにくく、歯垢の形成を防止しうる。当該糖アルコールは、低カロリー甘味料として用いられる。 This sugar alcohol is difficult to be metabolized to acid by oral bacteria and can prevent the formation of dental plaque. The sugar alcohol is used as a low calorie sweetener.
 糖アルコールとしては、特に限定されないが、エリトリトール、マルチトール、パラチノース等が挙げられる。これらの糖アルコールは、単独で用いても、2種以上を混合して用いてもよい。なお、高カロリー栄養組成物における糖アルコールの含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 The sugar alcohol is not particularly limited, and examples include erythritol, maltitol, palatinose and the like. These sugar alcohols may be used alone or in combination of two or more. In addition, content of the sugar alcohol in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
 クエン酸リンゴ酸カルシウム(CCM)およびカゼインホスホペプチド(CPP)は、カルシウムの吸収を促進し、骨形成を促進する機能を有する。これらのCCMおよびCPPは、単独で用いても、2種以上を混合して用いてもよい。また、CCMおよびCPPは、カルシウムと併用することが好ましい。なお、高カロリー栄養組成物におけるCCMおよびCPPの含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 Calcium citrate malate (CCM) and casein phosphopeptide (CPP) have functions of promoting calcium absorption and promoting bone formation. These CCMs and CPPs may be used alone or in combination of two or more. In addition, CCM and CPP are preferably used in combination with calcium. In addition, content of CCM and CPP in a high calorie nutrient composition is suitably adjusted by the subject etc. who apply a high calorie nutrient composition.
 食品添加物は、高カロリー栄養組成物の加工もしくは保存の目的で、高カロリー栄養組成物に添加、混和、湿潤その他の方法によって使用するものである。 The food additive is used by adding, blending, wetting or the like to the high calorie nutrient composition for the purpose of processing or storing the high calorie nutrient composition.
 食品添加物としては、栄養強化の目的以外にも、例えば、グルコン酸亜鉛およびグルコン酸銅、アスコルビン酸2-グルコシド、シクロデキストリン、保存料、防かび剤、酸化防止剤、着色料、マスキング剤、pH調整剤、酸味剤、香料、消泡剤等が挙げられる。 As food additives, in addition to the purpose of fortification, for example, zinc gluconate and copper gluconate, ascorbic acid 2-glucoside, cyclodextrin, preservatives, fungicides, antioxidants, coloring agents, masking agents, pH adjusters, acidulants, flavors, antifoaming agents, etc.
 アスコルビン酸2-グルコシドは、ビタミンC(アスコルビン酸)の2位の水酸基にグルコースがα-配位で結合した化合物であり、酸素の攻撃を受けないため通常のビタミンCよりも安定性が高いビタミンC誘導体である。アスコルビン酸2-グルコシドによって効率的にビタミンCを吸収することができる。アスコルビン酸2-グルコシドの含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 Ascorbic acid 2-glucoside is a compound in which glucose is bonded to the hydroxyl group at the 2-position of vitamin C (ascorbic acid) by α-coordination, and is a vitamin with higher stability than ordinary vitamin C because it is not attacked by oxygen. C derivative. Ascorbic acid 2-glucoside can efficiently absorb vitamin C. The content of ascorbic acid 2-glucoside is appropriately adjusted by the subject or the like who applies the high calorie nutritional composition.
 シクロデキストリンとは、グルコースがグルコシド結合によって結合し、環状構造をとった環状オリゴ糖である。6個のグルコースからなるものをα-シクロデキストリン、7個のグルコースからなるものをβ-シクロデキストリン、8個のグルコースからなるものをγ-シクロデキストリンという。シクロデキストリンは、アレルギー抑制効果、血糖値上昇抑制効果、乳化作用等の機能を有する。シクロデキストリンは、単独で用いても、2種以上を混合して用いてもよい。シクロデキストリンの含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 Cyclodextrin is a cyclic oligosaccharide having a cyclic structure in which glucose is linked by a glucosidic bond. Those consisting of six glucose are called α-cyclodextrin, those consisting of seven glucose are called β-cyclodextrin, and those consisting of eight glucose are called γ-cyclodextrin. Cyclodextrins have functions such as an allergy suppressive effect, a blood glucose level increase suppressive effect, and an emulsifying action. Cyclodextrin may be used alone or as a mixture of two or more. The content of cyclodextrin is appropriately adjusted by the subject or the like who applies the high calorie nutrient composition.
 酸化防止剤は、酸化による変質を防止する機能を有する。酸化防止剤としては、特に限定されないが、アスコルビン酸およびそのナトリウム塩、エリソルビン酸およびそのナトリウム塩等が用いられる。これらの酸化防止剤は、単独で用いても、2種以上を混合して用いてもよい。 The antioxidant has a function of preventing deterioration due to oxidation. The antioxidant is not particularly limited, and ascorbic acid and its sodium salt, erythorbic acid and its sodium salt, etc. may be used. These antioxidants may be used alone or in combination of two or more.
 着色料は、高カロリー栄養組成物を、美しく見せる機能を有する。着色料としては、特に限定されないが、食用タール色素(食用赤色2号、3号、40号、102号、104号、105号、および106号、食用青色1号および2号、食用黄色4号および5号、食用緑色3号等)、β-カロテン、水溶性アナトー、クロロフィル誘導体(クロロフィルa、クロロフィルb、銅クロロフィル、銅クロロフィリンナトリウム、鉄クロロフィリンナトリウム等)、リボフラビン、三二酸化鉄、二酸化チタン、ベニバナ黄色素、コチニール色素、クチナシ黄色素、ウコン色素、赤キャベツ色素、ビートレッド、ブドウ果皮色素、パプリカ色素、カラメル等が挙げられる。これらの着色料は、単独で用いても、2種以上を混合して用いてもよい。 The colorant has the function of making the high calorie nutritional composition look beautiful. Although it does not specifically limit as a coloring agent, Edible tar pigment (edible red 2, 3, 40, 102, 104, 105, and 106, Edible blue 1 and 2, Edible yellow 4, Edible yellow 4 And 5, food green No. 3, etc.), β-carotene, water-soluble anatto, chlorophyll derivatives (chlorophyll a, chlorophyll b, copper chlorophyll, sodium copper chlorophyllin, sodium iron chlorophyllin etc), riboflavin, ferric oxide, titanium dioxide, Examples thereof include safflower yellow pigment, cochineal pigment, gardenia yellow pigment, turmeric pigment, red cabbage pigment, beet red, grape skin pigment, paprika pigment, caramel and the like. These colorants may be used alone or in combination of two or more.
 マスキング剤は、高カロリー栄養組成物における原料由来の独特のえぐ味等を抑え、隠す機能を有する。マスキング剤としては、特に限定されないが、サッカリンおよびそのナトリウム塩、キシリトール、アスパルテーム、スクラロース、アセスルファムカリウム、ズルチン、チクロ(サイクラミン酸)、ネオテーム、トレハロース、エリスリトール、マルチトース、パラチノース、ソルビトール、甘草抽出物、ステビア、ソーマチン、クルクリン、リチルリチン酸二ナトリウム等が挙げられる。これらのマスキング剤は、単独で用いても、2種以上を混合して用いてもよい。 The masking agent has a function to suppress and hide unique bitter taste and the like derived from the raw material in the high calorie nutritional composition. The masking agent is not particularly limited, but saccharin and its sodium salt, xylitol, aspartame, sucralose, acesulfame potassium, duculin, ticlo (cyclamic acid), neotame, trehalose, erythritol, maltose, palatinose, sorbitol, licorice extract, stevia , Thaumatin, curculin, disodium lytyllithium acid and the like. These masking agents may be used alone or in combination of two or more.
 pH調整剤は、高カロリー栄養組成物のpHを調整する機能を有する。pH調整剤としては、特に限定されないが、クエン酸、グルコン酸、コハク酸、炭酸カリウム、炭酸水素ナトリウム、二酸化炭素、乳酸、乳酸ナトリウム、クエン酸ナトリウム、アジピン酸等が用いられうる。これらのpH調整剤は単独で用いても、2種以上を混合して用いてもよい。 The pH adjuster has a function of adjusting the pH of the high calorie nutrient composition. The pH adjuster is not particularly limited, and citric acid, gluconic acid, succinic acid, potassium carbonate, sodium hydrogencarbonate, carbon dioxide, lactic acid, sodium lactate, sodium citrate, adipic acid and the like may be used. These pH adjusters may be used alone or in combination of two or more.
 なお、高カロリー栄養組成物は、pH調整剤によりpHが調整されることで、そのpHは、3.0以上4.0以下であることが好ましく、4.0程度であることがより好ましい。高カロリー栄養組成物中のpHが3.0未満の場合、酸味が強く感じられ、風味が損なわれるおそれがある。高カロリー栄養組成物中のpHが4.0を超えると、真菌類などの微生物が繁殖する可能性が高くなるため、食品としての安全性が保たれないおそれがある。これにより、高カロリー栄養組成物の長期安定化を図ることができるとともに、高カロリー栄養組成物を食する際に、摂取者は、強度の酸味を感じることなく食することができる。 In addition, it is preferable that the pH is 3.0 or more and 4.0 or less, and it is more preferable that it is about 4.0 by adjusting pH by a pH adjuster. If the pH in the high-calorie nutrition composition is less than 3.0, the sour taste is felt strongly and the flavor may be lost. If the pH in the high-calorie nutrition composition exceeds 4.0, the possibility of propagation of microorganisms such as fungi is increased, and the safety as a food may not be maintained. Thereby, while being able to aim at long-term stabilization of a high-calorie nutrition composition, when eating a high-calorie nutrition composition, a user can eat without feeling strong sourness.
 酸味料は、高カロリー栄養組成物への酸味の付与、高カロリー栄養組成物の酸化の防止、およびpHの調整等の機能を有する。酸味料としては、特に限定されないが、酢酸、クエン酸、コハク酸、乳酸、リンゴ酸、酒石酸、グルコン酸、リン酸等が挙げられる。これらの酸味料は単独で用いても、2種以上を混合して用いてもよい。 The acidulant has functions such as addition of acidity to a high calorie nutrient composition, prevention of oxidation of the high calorie nutrient composition, and adjustment of pH. Examples of the acidulant include, but are not limited to, acetic acid, citric acid, succinic acid, lactic acid, malic acid, tartaric acid, gluconic acid, and phosphoric acid. These acidulants may be used alone or in combination of two or more.
 香料は、高カロリー栄養組成物の着香・嬌臭する機能を有する。香料としては、特に限定されないが、アセトフェノン、α-アミルシンナムアルデヒド、アニスアルデヒド、ベンズアルデヒド、酢酸ベンジル、ベンジルアルコール、シンナムアルデヒド、ケイ皮酸、シトラール、シトロネラール、シトロネロール、デカナール、デカノール、アセト酢酸エチル、ケイ皮酸エチル、デカン酸エチル、エチルバニリン、オイゲノール、ゲラニオール、酢酸イソアミル、酪酸イソアミル、フェニル酢酸イソアミル、dl-メントール、l-メントール、サリチル酸メチル、ピペロナール、プロピオン酸、テルピネオール、バニリン、d-ボルネオール等が挙げられる。これらの香料は、単独で用いても、2種以上を混合して用いてもよい。 The flavor has the function of flavoring and deodorizing the high calorie nutritional composition. Examples of the flavor include, but are not limited to, acetophenone, α-amylcinnamaldehyde, anisaldehyde, benzaldehyde, benzyl acetate, benzyl acetate, benzyl alcohol, cinnamaldehyde, cinnamic acid, citral, citronellal, citronellol, decanol, decanol, ethyl acetoacetate, silica Ethyl benzoate, ethyl decanoate, ethyl vanillin, eugenol, geraniol, isoamyl acetate, isoamyl butyrate, isoamyl phenylacetate, dl-menthol, l-menthol, methyl salicylate, piperonal, propionic acid, terpineol, vanillin, d-borneol etc. It can be mentioned. These perfumes may be used alone or in combination of two or more.
 安定剤は、高カロリー栄養組成物の食感改良とともに製造工程の安定化に寄与する機能を有する。安定剤としては、一般的に使用されている安定剤を用いることができる。具体的には、例えば、寒天、ゼラチン、セルロース、キチン、デキストラン、分岐デキストラン、グリコーゲン、イヌリン、マンナン、グルコマンナン、キシラン、プルラン、アルギン酸、アルギン酸塩、カルボキシメチルセルロース、ヒドロキシプロピルセルロース、サイクロデキストリン、ファーセレラン、加工澱粉、カラギーナン、ペクチン、ローカストビーンガム、グァーガム、グァーガム分解物、キサンタンガム、タマリンドガム、アラビアガム、ジェランガム、植物性たんぱく質、植物性たんぱく質分解物、動物性たんぱく質、動物性たんぱく質分解物等が挙げられる。これらの安定剤は、単独で用いても、2種以上を混合して安定剤として用いてもよい。 Stabilizers have the function of contributing to the stabilization of the manufacturing process as well as the texture improvement of the high calorie nutritional composition. As a stabilizer, the stabilizer generally used can be used. Specifically, for example, agar, gelatin, cellulose, chitin, dextran, branched dextran, glycogen, inulin, mannan, glucomannan, xylan, pullulan, alginic acid, alginic acid salt, carboxymethylcellulose, hydroxypropylcellulose, cyclodextrin, phalcerodine, Modified starch, carrageenan, pectin, locust bean gum, guar gum, guar gum decomposition product, xanthan gum, tamarind gum, gum arabic, gellan gum, vegetable protein, vegetable protein decomposition product, animal protein, animal protein decomposition product, etc. may be mentioned. . These stabilizers may be used alone, or two or more may be mixed and used as a stabilizer.
 なお、これらは市販されているものを用いることができ、例えば、寒天の市販品としては、例えば、ウルトラ即溶性寒天 UX-30、ウルトラ即溶性寒天 UX-100、ウルトラ即溶性寒天 UX-200、ウルトラ寒天 AX-30、ウルトラ寒天 AX-100、ウルトラ寒天 AX-200、ウルトラ寒天 BX-30、ウルトラ寒天 BX-100、ウルトラ寒天 BX-200、ウルトラ寒天イーナ、伊那寒天カリコリカン(全て伊那食品工業株式会社製)等が挙げられ、ペクチンの市販品としては、例えば、GENUペクチンYM-150-LJ、GENUペクチンYM-150-LJ-TF、GENUペクチンYM-115-H-J、GENUペクチンYM-115-LJ、GENUペクチンJM-150-J、GENUペクチンJMJ-J、GENUペクチンLM-105AS-J、GENUペクチンLM-101AS-JS-J、GENUペクチンLM-102AS-J、GENUペクチンLM-84AS、GENUペクチンLM-104AS-J、GENUペクチンLM-104AS-FS-J(全てCP Kelco社製)が挙げられる。 In addition, these can use what is marketed, for example, as a commercial item of agar, for example, ultra-quick dissolving agar UX-30, ultra-quick dissolving agar UX-100, ultra-quick dissolving agar UX-200, Ultra Agar AX-30, Ultra Agar AX-100, Ultra Agar AX-200, Ultra Agar BX-30, Ultra Agar BX-100, Ultra Agar BX-200, Ultra Agar Eana, Ina Agar Commercially available products of pectin include, for example, GENU pectin YM-150-LJ, GENU pectin YM-150-LJ-TF, GENU pectin YM-115-HJ, GENU pectin YM-115-. LJ, GENU Pectin JM-150-J, GEN Pectin JMJ-J, GENU Pectin LM-105 AS-J, GENU Pectin LM-101 AS-JS-J, GENU Pectin LM-102 AS-J, GENU Pectin LM-84 AS, GENU Pectin LM-104 AS-J, GENU Pectin LM-104 AS -FS-J (all manufactured by CP Kelco).
 なお、安定剤は、前述した食物繊維としての作用を兼ねることもできる。安定剤の含有量は、食感、安定性等を考慮して適宜調節される。 In addition, a stabilizer can also serve as the effect as a dietary fiber mentioned above. The content of the stabilizer is appropriately adjusted in consideration of the texture, stability and the like.
 ここで、本発明では、高カロリー栄養組成物は、前述した、機能成分としての食物繊維、および、安定剤として機能する寒天を含んでいる。このように高カロリー栄養組成物に寒天が含まれることで、食物繊維および安定剤としての機能を寒天に発揮させて、高カロリー栄養組成物を、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散されており、安定化が図られたものとすることができる。さらに、高カロリー栄養組成物の25℃での粘度を前述した範囲内、すなわち、3,500mPa・s以上17,500mPa・s以下、好ましくは5,000mPa・s以上15,000mPa・s以下に比較的容易に設定することができる。 Here, in the present invention, the high-calorie nutrition composition contains the above-mentioned dietary fiber as a functional component and agar which functions as a stabilizer. Thus, by containing agar in the high-calorie nutrition composition, the function as a dietary fiber and stabilizer is exerted on the agar, and the high-calorie nutrition composition is excellent in protein, lipid and carbohydrate as a major nutrient. It can be dispersed without separation with stability, and stabilization can be achieved. Furthermore, the viscosity at 25 ° C. of the high-calorie nutrition composition is within the above-mentioned range, ie, 3500 mPa · s or more and 17,500 mPa · s or less, preferably 5,000 mPa · s or more and 15,000 mPa · s or less Can be set easily.
 また、高カロリー栄養組成物における、寒天の含有量は、100mL中、0.05g以上0.32g以下であることが好ましく、0.12g以上0.30g以下であることがより好ましい。これにより、高カロリー栄養組成物の25℃での粘度を前述した範囲内により確実に設定することができる。 Further, the content of agar in the high calorie nutritional composition is preferably 0.05 g or more and 0.32 g or less in 100 mL, and more preferably 0.12 g or more and 0.30 g or less. Thereby, the viscosity at 25 degrees C of a high calorie nutrient composition can be set more reliably within the range mentioned above.
 さらに、高カロリー栄養組成物は、前記栄養素および寒天の他に、炭水化物(多糖)、食物繊維および安定剤としてペクチンを含有することが好ましい。これにより、高カロリー栄養組成物の25℃での粘度を前述した範囲内により確実に設定することができる。なお、この場合、高カロリー栄養組成物における、ペクチンの含有量は、100mL中、好ましくは0.05g以上0.3g以下、より好ましくは0.1g以上0.2g以下に設定される。これにより、前記効果をより顕著に発揮させることができる。 Furthermore, it is preferable that the high-calorie nutrition composition contains, in addition to the nutrients and agar, a carbohydrate (polysaccharide), dietary fiber and pectin as a stabilizer. Thereby, the viscosity at 25 degrees C of a high calorie nutrient composition can be set more reliably within the range mentioned above. In this case, the content of pectin in the high-calorie nutrition composition is set to 100 g, preferably 0.05 g or more and 0.3 g or less, more preferably 0.1 g or more and 0.2 g or less. Thereby, the said effect can be exhibited more notably.
 その他の添加剤として、例えば、α-アミラーゼ、β-アミラーゼ、グルコアミラーゼ、グルコースイソメラーゼ、トレハロース生成酵素、トレハロース遊離酵素、グルタミナーゼ等の酵素や酵母等が用いられる。これらその他の添加物の含有量は、高カロリー栄養組成物を適用する対象者等によって適宜調節される。 As other additives, for example, enzymes such as α-amylase, β-amylase, glucoamylase, glucose isomerase, trehalose producing enzyme, trehalose releasing enzyme, glutaminase, yeast and the like are used. The content of these other additives is appropriately adjusted by the subject or the like who applies the high calorie nutrient composition.
 なお、上述したような高カロリー栄養組成物は、公知の方法によって製造することができる。 In addition, the above-mentioned high-calorie nutrition composition can be manufactured by a well-known method.
<<容器>>
 容器10は、本実施形態では、ストロー付きアルミパウチであり、上述した高カロリー栄養組成物が充填され、この高カロリー栄養組成物を持ち運び(輸送)する際、および、摂取する際の容器としての機能を併せ持つ。
<< container >>
The container 10 in the present embodiment is an aluminum pouch with a straw, which is filled with the above-described high-calorie nutrition composition, and is used as a container when carrying (transporting) and ingesting this high-calorie nutrition composition. It also has a function.
 この容器10は、図1に示すように、袋状をなし高カロリー栄養組成物が充填される容器本体30と、容器本体30の上端部に設けられ、容器本体30に連通する開口部20と、開口部20に着脱可能に設けられた蓋体25とを有している。 As shown in FIG. 1, the container 10 is a bag-shaped container body 30 to be filled with a high-calorie nutrition composition, and an opening 20 provided at the upper end of the container body 30 and communicating with the container body 30. And a lid 25 detachably provided in the opening 20.
 容器本体30は、本実施形態では、平面視形状が長方形状をなし、両側部に内側に折り込まれた折込部を有するガゼットタイプのパウチ容器であり、その容量が100mLとなるように、その高さA120mm×幅B80mm×ガゼット幅21mmに設定されている。 In the present embodiment, the container body 30 is a gusset-type pouch container having a rectangular shape in a plan view shape and having a folded portion folded inward on both sides, and the height thereof is 100 mL so that the volume is 100 mL. It is set to A120 mm x width B 80 mm x gusset width 21 mm.
 この容器本体30に、熱量が2.5kcal/mL以上4.5kcal/mL以下の高カロリー栄養組成物が充填されており、その充填量が100mLとなっている。そのため、例えば、朝食、昼食および夕食の三食に、包装体1により、容器本体30内に充填されている高カロリー栄養組成物を取得することで、750kcal以上1350kcal以下のエネルギーの取得が可能である。したがって、包装体1による高カロリー栄養組成物の三食の摂取によって、高齢者が1日で取得することが望ましいエネルギー量を満足することができる。よって、高カロリー栄養組成物を摂取する摂取者(高齢者)は、容器本体30に充填されている、100mLと言う少量の高カロリー栄養組成物を食するだけで、高齢者が1日で取得することが望ましいエネルギー量が達成される。 The container body 30 is filled with a high-calorie nutritional composition having a heat quantity of 2.5 kcal / mL or more and 4.5 kcal / mL or less, and the filling amount is 100 mL. Therefore, it is possible to obtain energy of 750 kcal or more and 1350 kcal or less by, for example, acquiring the high-calorie nutrition composition filled in the container body 30 with the package 1 at breakfast, lunch, and dinner three meals. is there. Therefore, by the intake of three meals of the high-calorie nutrition composition by the package 1, it is possible to satisfy the amount of energy that it is desirable for the elderly to obtain in one day. Therefore, the ingested person (the elderly person) who ingests the high-calorie nutrition composition gets the elderly person in one day only by eating a small amount of the high-calorie nutrition composition said to be 100 mL filled in the container body 30 The amount of energy desired to be achieved is achieved.
 なお、容器10(容器本体30)は、その容量が上記のように100mLである場合に限らず、50mL~200mL程度の容量を有するものであってもよい。かかる範囲内の容量を有するものであれば、持ち運びも容易であり、かつ、望ましいとされるエネルギー量を取得することができる。 The container 10 (container body 30) is not limited to the case where the volume is 100 mL as described above, and may have a volume of about 50 mL to 200 mL. If it has the capacity | capacitance within this range, carrying is also easy, and it can acquire the amount of energy made desirable.
 この容器本体30は、例えば、アルミホイルの両面が樹脂材料で構成される被覆層で被覆されたフィルム材で構成される。 The container body 30 is made of, for example, a film material in which both surfaces of an aluminum foil are coated with a covering layer made of a resin material.
 開口部20は、その全体形状が円筒状をなし、容器本体30の上端部のほぼ中央に設けられ、これにより、容器本体30に連通するストローとして機能する。 The opening 20 has a cylindrical shape as a whole and is provided substantially at the center of the upper end of the container body 30, thereby functioning as a straw communicating with the container body 30.
 この開口部20を介して、包装体1の製造時には、高カロリー栄養組成物が容器本体30内に充填され、さらに、摂取者により高カロリー栄養組成物を食する際には、容器本体30の押圧により容器本体30から排出される。 The high-calorie nutrition composition is filled in the container body 30 at the time of manufacturing the package 1 through the opening 20, and when the high-calorie nutrition composition is eaten by the user, The pressure is discharged from the container body 30.
 この開口部20は、その内口径(直径)が、本実施形態では、8.33mmに設定されている。内口径(開口径)をかかる大きさに設定し、さらに、前述の通り、25℃での粘度が3,500mPa・s以上17,500mPa・s以下である高カロリー栄養組成物が容器本体30に充填されることで、摂取者は、液だれを生じさせることなく、容器本体30の押圧により、高カロリー栄養組成物を、開口部20を介して容器本体30から容易に排出させて、経口により高カロリー栄養組成物を摂取者が取得する(食する)ことができる。また、この際、開口部20から50mL/min以上60mL/min以下の速度で、高カロリー栄養組成物を排出するとき、容器本体30を押圧する吐出圧力を好ましくは20kPa以下、より好ましくは10kPa以下に設定することができる。これにより、高齢者のように握力が低下した摂取者であっても、手による容器本体30の押圧により、開口部20を介して、容器本体30から高カロリー栄養組成物を排出させて、食することができる。 The inner diameter (diameter) of the opening 20 is set to 8.33 mm in the present embodiment. The internal diameter (opening diameter) is set to such a size, and as described above, the high-calorie nutrition composition having a viscosity of 3,500 mPa · s or more and 17,500 mPa · s or less at 25 ° C. By being filled, the user can easily discharge the high-calorie nutrition composition from the container body 30 through the opening 20 by pressing the container body 30 without causing dripping, and then orally A high calorie nutritional composition can be obtained (eating) by the consumer. At this time, when discharging the high-calorie nutrition composition from the opening 20 at a rate of 50 mL / min to 60 mL / min, the discharge pressure for pressing the container body 30 is preferably 20 kPa or less, more preferably 10 kPa or less It can be set to As a result, even a user who has a reduced grip, such as an elderly person, can discharge the high-calorie nutrition composition from the container body 30 through the opening 20 by pressing the container body 30 by hand. can do.
 また、開口部20は、その外周面の上端側に、雄ネジ(図示せず)を備えている。さらに、蓋体25は、その全体形状が有底の円筒状をなし、その内周面に、雌ネジ(図示せず)を備えている。開口部20が備える雄ネジに、蓋体25が備える雌ネジが螺合することで、蓋体25としての機能が発揮して、図1に示すように、開口部20の密閉性が確保される。 Further, the opening 20 is provided with a male screw (not shown) on the upper end side of the outer peripheral surface thereof. Furthermore, the lid 25 is in the form of a cylinder having an overall shape with a bottom and is provided with a female screw (not shown) on the inner peripheral surface thereof. By screwing the female screw with which the lid 25 is provided to the male screw with which the opening 20 is provided, the function as the lid 25 is exerted, and as shown in FIG. 1, the hermeticity of the opening 20 is ensured. Ru.
 この蓋体25は、着脱可能であるため、包装体1の輸送・保管時には、図1に示すように、装着された状態とされて開口部20ひいては容器本体30の密閉性が確保され、容器本体30への高カロリー栄養組成物の充填時および高カロリー栄養組成物の摂取時には、装脱された状態とされ、開口部20を介した高カロリー栄養組成物の充填および排出が可能となる。 Since the lid 25 is removable, as shown in FIG. 1, when the package 1 is transported and stored, the lid 25 is put in a mounted state, and the sealing performance of the opening 20 and the container body 30 is secured. At the time of filling of the high-calorie nutrition composition into the main body 30 and at the time of intake of the high-calorie nutrition composition, the body 30 is in a state of being loaded and unloaded, and filling and discharge of the high-calorie nutrition composition through the opening 20 become possible.
 これらの開口部20および蓋体25は、例えば、高密度ポリエチレン(HDPE)のような樹脂材料で構成される。 The opening 20 and the lid 25 are made of, for example, a resin material such as high density polyethylene (HDPE).
 なお、包装体1は、容器本体30に、連続殺菌された後の高カロリー栄養組成物が充填されることで製品化がなされている。この連続殺菌の方法としては、特に限定されないが、例えば、超高温短時間(UHT)殺菌、熱水殺菌、バッチ式殺菌、およびこれらの組み合わせが挙げられる。 The packaging body 1 is commercialized by filling the container body 30 with the high-calorie nutrition composition after being continuously sterilized. The continuous sterilization method is not particularly limited, and examples thereof include ultra-high-temperature short-time (UHT) sterilization, hot water sterilization, batch sterilization, and a combination thereof.
 また、高カロリー栄養組成物を充填する容器10、すなわち、包装体1が備える容器10としては、本実施形態で説明した、ストロー付きアルミパウチに、限定されず、例えば、他の公知の容器が用いられ、この容器としては、テトラパック、カート缶、ガラス容器、金属缶、プラスチック容器等が挙げられる。 Also, the container 10 filled with the high-calorie nutrition composition, ie, the container 10 provided in the package 1 is not limited to the aluminum pouch with straw described in the present embodiment, for example, other known containers may be used. As this container, tetra-pack, cart can, glass container, metal can, plastic container etc. may be mentioned.
 さらに、高カロリー栄養組成物は、上述したように、経口摂取する流動食に適用できる他、PEGチューブ等を介して経腸投与する経腸栄養剤に適用することも可能である。 Furthermore, as described above, the high-calorie nutrition composition can be applied not only to a liquid food to be taken orally but also to an enteral nutrient for enteral administration via a PEG tube or the like.
 以上、本発明の高カロリー栄養組成物および包装体を好適実施形態に基づいて説明したが、本発明はこれらに限定されるものではない。例えば、本発明の高カロリー栄養組成物に含まれる各種の栄養素は、同様の機能を発揮し得る任意のものと置換することができ、あるいは、任意の機能を有するものを付加することもできる。 As mentioned above, although the high calorie nutrition composition and the package of the present invention were explained based on a suitable embodiment, the present invention is not limited to these. For example, the various nutrients contained in the high calorie nutritional composition of the present invention can be replaced with any one capable of performing the same function, or one having an arbitrary function can be added.
 以下、実施例を挙げて本発明を具体的に説明するが、本発明はこれらに限定されるものではない。 EXAMPLES Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited thereto.
 1.寒天の含有量の検討
(実施例1A)
 以下に1700L仕込み時の調合方法を記す。各原料の配合量は、表1に示す通りである。
1. Examination of agar content (Example 1A)
The method of preparation at the time of 1700L preparation is described below. The blending amounts of the respective raw materials are as shown in Table 1.
 調合水450kgを計量し、湯浴にて80℃以上に加温した。次いで、寒天、ペクチン、リン酸二水素ナトリウム、リン酸二水素カリウム、塩化カリウム、有機酸モノグリセライド、ポリグリセリンエステルを加え、十分に溶解させた後に65℃まで冷却し、コラーゲンペプチド(ウェルコラーゲン、分子量:4,300、日本新薬株式会社製)、乳清たんぱく質(WPC550、Fonterra社製)を添加した。 450 kg of mixed water was measured, and heated to 80 ° C. or more in a hot water bath. Next, add agar, pectin, sodium dihydrogen phosphate, potassium dihydrogen phosphate, potassium chloride, organic acid monoglyceride, polyglycerin ester, dissolve well, and then cool to 65 ° C, collagen peptide (well collagen, molecular weight 4,300 (manufactured by Nippon Shinyaku Co., Ltd.) and whey protein (WPC 550, manufactured by Fonterra) were added.
 当該溶液に植物混合油、中鎖脂肪酸を65℃で混合した分散液を混合した。さらに、グラニュー糖、リン酸三カルシウム、塩化マグネシウム、クエン酸鉄、グルコン酸亜鉛、グルコン酸銅、セレン酵母、モリブデン酵母、クロム酵母、マンガン酵母、昆布ミネラル、クエン酸、リンゴ酸、甘味料、水溶性ビタミンミックス、ビタミンC、L-カルニチン、ビタミンK2油、デキストリン、カラメル、脂溶性ビタミンミックス、クエン酸三ナトリウム、消泡剤、ニコチン酸アミド、発酵乳、アップルフレーバーを適宜添加して攪拌した。全量が1700Lとなるまで水を添加し、均一な状態となるまで溶解分散させた。 The mixed solution was mixed with vegetable mixed oil and medium chain fatty acid at 65 ° C. In addition, granulated sugar, tricalcium phosphate, magnesium chloride, iron citrate, zinc gluconate, copper gluconate, selenium yeast, molybdenum yeast, chromium yeast, manganese yeast, kelp mineral, citric acid, malic acid, sweetener, water soluble Vitamin mix, vitamin C, L-carnitine, vitamin K2 oil, dextrin, caramel, fat-soluble vitamin mix, trisodium citrate, antifoamer, nicotinamide, fermented milk, apple flavor were appropriately added and stirred. Water was added until the total amount reached 1700 L, and dissolved and dispersed until uniform.
 得られた溶液は、均質化し、1個当たり100mLとなるようにストロー(口栓)付きのアルミパウチ(図1参照)に充填後、90℃、10分間の殺菌処理を行った。前記殺菌処理の後、冷却することで、高カロリー栄養組成物(高濃度栄養組成物)が充填された包装体を製造した。 The solution obtained was homogenized, filled in an aluminum pouch with a straw (plug) (see FIG. 1) so as to be 100 mL per one, and then sterilized at 90 ° C. for 10 minutes. It cooled after the said sterilizing process, and manufactured the package body with which the high calorie nutrient composition (high concentration nutrient composition) was filled.
Figure JPOXMLDOC01-appb-T000001
Figure JPOXMLDOC01-appb-T000001
 なお、得られた栄養組成物において、蛋白の含有量は14.0g/100mL(コラーゲンペプチドの濃度は10.0g/100mL、乳清たんぱく質の濃度は4.00g/100mL)、炭水化物の含有量は37.4g/100mL、脂質の含有量は21.6g/100mLであった。 In the obtained nutritional composition, the content of protein is 14.0 g / 100 mL (the concentration of collagen peptide is 10.0 g / 100 mL, the concentration of whey protein is 4.00 g / 100 mL), and the content of carbohydrate is The content of 37.4 g / 100 mL and lipid was 21.6 g / 100 mL.
 次いで、得られた栄養組成物について性状を観察し、各種物性を評価した。評価方法は以下の通りである。 Subsequently, the properties of the obtained nutritional composition were observed to evaluate various physical properties. The evaluation method is as follows.
(1)均一性:50メッシュの篩で濾過した後、試料の残渣状況を目視で確認し、以下の評価によって評価した。 (1) Uniformity: After filtering through a 50-mesh sieve, the residual state of the sample was visually confirmed and evaluated by the following evaluation.
 ◎:残渣無
 ×:残渣有
◎: no residue ×: residue present
(2)pH:栄養組成物を25℃で24時間静置後、pH測定器METTLER TOLEDO MP220(METTLER TOLEDO社製)を用いてpHを測定した。 (2) pH: The nutrient composition was allowed to stand at 25 ° C. for 24 hours, and then the pH was measured using a pH meter METTLER TOLEDO MP220 (manufactured by METTLER TOLEDO).
(3)粘度:栄養組成物を25℃で24時間静置後、B型回転粘度計(メーカー:BROOKFIELD、型式:DV-II+Pro、測定条件:回転速度6rpm、測定時間1分、ローターNo.63)を用いて測定した。 (3) Viscosity: After leaving the nutritional composition at rest for 24 hours at 25 ° C., a B-type rotational viscometer (Manufacturer: BROOKFIELD, Model: DV-II + Pro, measurement conditions: rotational speed 6 rpm, measurement time 1 minute, rotor No. 63) ) Was used.
(4)安定性:製造後6ヶ月後に栄養組成物約100mLを容器に出した際の様子を観察して、以下の評価によって評価した。 (4) Stability: The condition when about 100 mL of the nutritional composition was put out in a container 6 months after production was observed and evaluated by the following evaluation.
 ◎:分離無
 ○:若干の離水による分離が認められる
 ×:離水により二層に分離、または、寒天の凝集が発生
:: no separation ○: separation due to slight syneresis is observed ×: separation into two layers due to syneresis, or aggregation of agar occurs
(5)液だれの有無:栄養組成物100mLを図1に示す容器10内に充填し、その後、開口部20からの液だれの有無、さらに、容器本体30を押圧した際の、栄養組成物(内容物)の排出のし易さについて観察した。 (5) Presence or absence of liquid dripping: 100 mL of the nutritional composition is filled in the container 10 shown in FIG. 1, and thereafter, the presence or absence of liquid dripping from the opening 20, and further, the nutritional composition when the container main body 30 is pressed The ease of discharge of (content) was observed.
 ◎:液だれなく、かつ、容器本体30の押圧により栄養組成物が容易に排出される
 ×:液だれが認められる、もしくは、容器本体30の押圧によっても栄養組成物が容易には排出されない
◎: No dripping and the nutritional composition is easily discharged by the pressure of the container body 30. x: Liquid dripping is recognized, or the nutritional composition is not easily discharged even by the pressure of the container body 30.
 得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、寒天の含有量は0.12g/100mL、粘度は7,785±269mPa・s、安定性は「◎」、液だれの有無は「◎」であった。結果を表2に示す。 Calorific value of the obtained nutritional composition is 4.0 kcal / mL, uniformity is "」 ", pH is 3.8, agar content is 0.12 g / 100 mL, viscosity is 7,785 ± 269 mPa · s, stable The sex was "◎" and the presence or absence of the liquid was "「 ". The results are shown in Table 2.
(実施例2A)
 実施例2Aにおいて、寒天の含有量が0.05g/100mLとなるように寒天の添加量を変更したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は3,753±254mPa・s、安定性は「〇」、液だれの有無は「◎」であった。結果を表2に示す。
Example 2A
The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.05 g / 100 mL in Example 2A. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “◎”, the pH is 3.8, the viscosity is 3,753 ± 254 mPa · s, the stability is “〇”, the presence or absence of liquid drip is It was "◎". The results are shown in Table 2.
(実施例3A)
 実施例3Aにおいて、寒天の含有量が0.24g/100mLとなるように寒天の添加量を変更したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は12,930±372mPa・s、安定性は「◎」、液だれの有無は「◎」であった。結果を表2に示す。
Example 3A
The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.24 g / 100 mL in Example 3A. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is "◎", the pH is 3.8, the viscosity is 12,930 ± 372 mPa · s, the stability is "、", the presence or absence of liquid drip is It was "◎". The results are shown in Table 2.
(実施例4A)
 実施例4Aにおいて、寒天の含有量が0.30g/100mLとなるように寒天の添加量を変更したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は14,484±811mPa・s、安定性は「◎」、液だれの有無は「◎」であった。結果を表2に示す。
Example 4A
The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed so that the agar content was 0.30 g / 100 mL in Example 4A. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is "◎", the pH is 3.8, the viscosity is 14,484 ± 811 mPa · s, the stability is "◎", the presence or absence of liquid drip It was "◎". The results are shown in Table 2.
(実施例5A)
 実施例5Aにおいて、寒天の含有量が0.32g/100mLとなるように寒天の添加量を変更したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は17,093±600mPa・s、安定性は「〇」、液だれの有無は「◎」であった。結果を表2に示す。
Example 5A
The nutritional composition was obtained by repeating exactly the same preparation method as in Example 1A, except that the amount of agar added was changed such that the content of agar was 0.32 g / 100 mL in Example 5A. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is "均一", the pH is 3.8, the viscosity is 17,093 ± 600 mPa · s, the stability is "「 ", the presence or absence of liquid drip is It was "◎". The results are shown in Table 2.
(比較例1A)
 比較例1Aにおいて、寒天の含有量が0.00g/100mLとなるように寒天の添加を省略したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は2,719±140mPa・s、安定性は「×」、液だれの有無は「×」であった。結果を表2に示す。
(Comparative example 1A)
In Comparative Example 1A, a nutritional composition was obtained by repeating the same preparation method as Example 1A except that addition of agar was omitted so that the agar content was 0.00 g / 100 mL. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “均一”, the pH is 3.8, the viscosity is 2,719 ± 140 mPa · s, the stability is “x”, the presence or absence of liquid drip is It was "x". The results are shown in Table 2.
(比較例2A)
 比較例2Aにおいて、寒天の含有量が0.35g/100mLとなるように寒天の添加量を変更したこと以外は、実施例1Aと全く同じ調製法を繰り返して栄養組成物を得た。得られた栄養組成物の熱量は4.0kcal/mL、均一性は「◎」、pHは3.8、粘度は25,128±2663mPa・s、安定性は「×」、液だれの有無は「×」であった。結果を表2に示す。
(Comparative example 2A)
In Comparative Example 2A, a nutritional composition was obtained by repeating the same preparation method as Example 1A except that the amount of agar added was changed so that the agar content was 0.35 g / 100 mL. The heat quantity of the obtained nutritional composition is 4.0 kcal / mL, the uniformity is “「 ”, the pH is 3.8, the viscosity is 25,128 ± 2663 mPa · s, the stability is“ x ”, the presence or absence of dripping is It was "x". The results are shown in Table 2.
Figure JPOXMLDOC01-appb-T000002
Figure JPOXMLDOC01-appb-T000002
Figure JPOXMLDOC01-appb-T000003
Figure JPOXMLDOC01-appb-T000003
 以上のことから明らかな通り、各実施例では、各比較例と比較して、栄養組成物における、寒天の含有量を適切な範囲に設定することにより、栄養組成物の25℃での粘度が3,500mPa・s以上17,500mPa・s以下の範囲内に設定され、これにより、栄養組成物の均一性および安定性が図られ、さらに、容器からの液だれも認められないことが明らかとなった。 As is apparent from the above, in each example, the viscosity of the nutritional composition at 25 ° C. is set by setting the agar content in the nutritional composition to an appropriate range in comparison with each comparative example. It is set in the range of 3,500 mPa · s or more and 17,500 mPa · s or less, which makes it possible to achieve uniformity and stability of the nutritional composition, and it is also apparent that no dripping from the container is observed. became.
 本発明の高カロリー栄養組成物は、たんぱく質、脂質、炭水化物を含む栄養素と、寒天を含有し、25℃での粘度が3,500mPa・s以上17,500mPa・s以下であり、かつ、熱量が2.5kcal/mL以上4.5kcal/mL以下である。そのため、少量の摂取によりエネルギーを十分に補給することができるとともに、三大栄養素をバランスよく取得することができ、かつ、三大栄養素としてのたんぱく質、脂質および炭水化物が優れた安定性をもって分離することなく分散している高カロリー栄養組成物、および、かかる高カロリー栄養組成物が容器に充填され、この高カロリー栄養組成物を、液だれを生じさせることなく、容易に補給することができる包装体を提供することができる。従って、本発明の高カロリー栄養組成物および包装体は、産業上の利用可能性を有する。 The high-calorie nutrition composition of the present invention contains a nutrient containing protein, lipid and carbohydrate, and agar, has a viscosity at 25 ° C. of not less than 3,500 mPa · s and not more than 17,500 mPa · s, and has an amount of heat of 2.5 kcal / mL or more and 4.5 kcal / mL or less. Therefore, it is possible to supply a sufficient amount of energy with a small amount of intake and to obtain three major nutrients in a balanced manner, and to separate proteins, lipids and carbohydrates as major nutrients with excellent stability. A high-calorie nutritional composition that is not dispersed and a package that can be filled with such a high-calorie nutritional composition in a container, and the high-calorie nutritional composition can be easily replenished without causing dripping. Can be provided. Thus, the high calorie nutritional composition and package of the present invention have industrial applicability.
 1      包装体
 10     容器
 20     開口部
 25     蓋体
 30     容器本体
Reference Signs List 1 package 10 container 20 opening 25 lid 30 container body

Claims (9)

  1.  たんぱく質、脂質、炭水化物を含む栄養素と、寒天を含有する高カロリー栄養組成物であって、
     25℃での粘度が3,500mPa・s以上17,500mPa・s以下であり、かつ、熱量が2.5kcal/mL以上4.5kcal/mL以下であることを特徴とする高カロリー栄養組成物。
    What is claimed is: 1. A high calorie nutritional composition comprising nutrients including proteins, lipids, carbohydrates and agar.
    A high-calorie nutritional composition characterized in that the viscosity at 25 ° C. is 3,500 mPa · s or more and 17,500 mPa · s or less, and the heat quantity is 2.5 kcal / mL or more and 4.5 kcal / mL or less.
  2.  さらに、ペクチンを含有する請求項1に記載の高カロリー栄養組成物。 The high calorie nutrient composition according to claim 1, further comprising pectin.
  3.  pHが3.0以上4.0以下である請求項1または2に記載の高カロリー栄養組成物。 The high calorie nutrient composition according to claim 1 or 2, wherein the pH is 3.0 or more and 4.0 or less.
  4.  当該高カロリー栄養組成物における、前記寒天の含有量は、100mL中、0.05g以上0.32g以下である請求項1ないし3のいずれか1項に記載の高カロリー栄養組成物。 The high calorie nutrition composition according to any one of claims 1 to 3, wherein a content of the agar in the high calorie nutrition composition is 0.05 g or more and 0.32 g or less in 100 mL.
  5.  当該高カロリー栄養組成物における、前記たんぱく質の含有量は、100mL中、10.0g以上30.0g以下である請求項1ないし4のいずれか1項に記載の高カロリー栄養組成物。 The high calorie nutrition composition according to any one of claims 1 to 4, wherein the content of the protein in the high calorie nutrition composition is 10.0 g or more and 30.0 g or less in 100 mL.
  6.  前記たんぱく質として、コラーゲンペプチドおよび乳清たんぱく質を含有する請求項1ないし5のいずれか1項に記載の高カロリー栄養組成物。 The high calorie nutrient composition according to any one of claims 1 to 5, wherein the protein comprises a collagen peptide and whey protein.
  7.  当該高カロリー栄養組成物における、前記脂質の含有量は、100mL中、8.0g以上30.0g以下である請求項1ないし6のいずれか1項に記載の高カロリー栄養組成物。 The high calorie nutritional composition according to any one of claims 1 to 6, wherein the content of the lipid in the high calorie nutritional composition is 8.0 g or more and 30.0 g or less in 100 mL.
  8.  当該高カロリー栄養組成物における、前記炭水化物の含有量は、100mL中、25.0g以上40.0g以下である請求項1ないし7のいずれか1項に記載の高カロリー栄養組成物。 The high calorie nutrition composition according to any one of claims 1 to 7, wherein a content of the carbohydrate in the high calorie nutrition composition is 25.0 g or more and 40.0 g or less in 100 mL.
  9.  請求項1ないし8のいずれか1項に記載の高カロリー栄養組成物と、前記高カロリー栄養組成物を充填した容器とを有することを特徴とする包装体。 A package comprising the high calorie nutrient composition according to any one of claims 1 to 8 and a container filled with the high calorie nutrient composition.
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JP2007126379A (en) * 2005-11-02 2007-05-24 Yaizu Suisankagaku Industry Co Ltd Method for producing acidic liquid enteral nutritive preparation
WO2013085059A1 (en) * 2011-12-09 2013-06-13 株式会社明治 Method for producing nutritional composition
WO2013125066A1 (en) * 2012-02-22 2013-08-29 テルモ株式会社 Semi-solidified nutrient for gastrostomy
JP2014003960A (en) * 2012-06-27 2014-01-16 Nof Corp Liquid nutritive composition
WO2014030605A1 (en) * 2012-08-20 2014-02-27 味の素株式会社 Nutritional composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007126379A (en) * 2005-11-02 2007-05-24 Yaizu Suisankagaku Industry Co Ltd Method for producing acidic liquid enteral nutritive preparation
WO2013085059A1 (en) * 2011-12-09 2013-06-13 株式会社明治 Method for producing nutritional composition
WO2013125066A1 (en) * 2012-02-22 2013-08-29 テルモ株式会社 Semi-solidified nutrient for gastrostomy
JP2014003960A (en) * 2012-06-27 2014-01-16 Nof Corp Liquid nutritive composition
WO2014030605A1 (en) * 2012-08-20 2014-02-27 味の素株式会社 Nutritional composition

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