WO2019012481A3 - Split g-quadruplexes for capture and detection of nucleic acids - Google Patents

Split g-quadruplexes for capture and detection of nucleic acids Download PDF

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Publication number
WO2019012481A3
WO2019012481A3 PCT/IB2018/055166 IB2018055166W WO2019012481A3 WO 2019012481 A3 WO2019012481 A3 WO 2019012481A3 IB 2018055166 W IB2018055166 W IB 2018055166W WO 2019012481 A3 WO2019012481 A3 WO 2019012481A3
Authority
WO
WIPO (PCT)
Prior art keywords
quadruplexes
split
detection
nucleic acids
capture
Prior art date
Application number
PCT/IB2018/055166
Other languages
French (fr)
Other versions
WO2019012481A2 (en
Inventor
John Katz
Original Assignee
John Katz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Katz filed Critical John Katz
Priority to US16/629,940 priority Critical patent/US20230193359A1/en
Priority to BR112020000638-6A priority patent/BR112020000638A2/en
Publication of WO2019012481A2 publication Critical patent/WO2019012481A2/en
Publication of WO2019012481A3 publication Critical patent/WO2019012481A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Abstract

Methods of using split G-quadruplexes associated with functional tags for associating said tags to target nucleic acids. Methods include use of split G- quadruplexes associated with detection tags for the detection of target nucleic acids, and use of split G- quadruplexes associated with capture tags for detection or capture of target nucleic acids.
PCT/IB2018/055166 2017-07-12 2018-07-12 Split g-quadruplexes for capture and detection of nucleic acids WO2019012481A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US16/629,940 US20230193359A1 (en) 2017-07-27 2018-07-12 Split G-Quadruplexes for Capture and Detection of Nucleic Acids
BR112020000638-6A BR112020000638A2 (en) 2017-07-12 2018-07-12 methods of associating a tag with a nucleic acid, to detect a nucleic acid and to capture a nucleic acid.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762531548P 2017-07-12 2017-07-12
US62/531,548 2017-07-12

Publications (2)

Publication Number Publication Date
WO2019012481A2 WO2019012481A2 (en) 2019-01-17
WO2019012481A3 true WO2019012481A3 (en) 2019-02-21

Family

ID=65002369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2018/055166 WO2019012481A2 (en) 2017-07-12 2018-07-12 Split g-quadruplexes for capture and detection of nucleic acids

Country Status (2)

Country Link
BR (1) BR112020000638A2 (en)
WO (1) WO2019012481A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109957608B (en) * 2019-03-05 2022-04-12 广东省生态环境技术研究所 Method and kit for label-free fluorescence detection of gene
CN112048547B (en) * 2019-06-06 2022-05-31 同济大学 Spinal muscular atrophy pathogenic gene detection kit and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005601A1 (en) * 2002-04-05 2004-01-08 Adam Siddiqui-Jain Methods for targeting quadruplex DNA
WO2010059944A1 (en) * 2008-11-21 2010-05-27 Columbia University A split dna enzyme for visual single nucleotide polymorphism typing
US20100297644A1 (en) * 2007-10-23 2010-11-25 Stratos Genomics Inc. High throughput nucleic acid sequencing by spacing
US20110059867A1 (en) * 2009-02-27 2011-03-10 Jinsang Kim Functionalized polydiacetylene sensors
US20130029853A1 (en) * 2008-12-11 2013-01-31 Pacific Biosciences Of California, Inc. Classification of nucleic acid templates

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005601A1 (en) * 2002-04-05 2004-01-08 Adam Siddiqui-Jain Methods for targeting quadruplex DNA
US20100297644A1 (en) * 2007-10-23 2010-11-25 Stratos Genomics Inc. High throughput nucleic acid sequencing by spacing
WO2010059944A1 (en) * 2008-11-21 2010-05-27 Columbia University A split dna enzyme for visual single nucleotide polymorphism typing
US20130029853A1 (en) * 2008-12-11 2013-01-31 Pacific Biosciences Of California, Inc. Classification of nucleic acid templates
US20110059867A1 (en) * 2009-02-27 2011-03-10 Jinsang Kim Functionalized polydiacetylene sensors

Also Published As

Publication number Publication date
BR112020000638A2 (en) 2020-07-14
WO2019012481A2 (en) 2019-01-17

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