WO2019004748A3 - 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법 - Google Patents

페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법 Download PDF

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Publication number
WO2019004748A3
WO2019004748A3 PCT/KR2018/007348 KR2018007348W WO2019004748A3 WO 2019004748 A3 WO2019004748 A3 WO 2019004748A3 KR 2018007348 W KR2018007348 W KR 2018007348W WO 2019004748 A3 WO2019004748 A3 WO 2019004748A3
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WO
WIPO (PCT)
Prior art keywords
diagnosis
occupational asthma
periostin
isocyanate
present
Prior art date
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PCT/KR2018/007348
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English (en)
French (fr)
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WO2019004748A9 (ko
WO2019004748A2 (ko
Inventor
박해심
이지호
최영우
겐지이주하라
Original Assignee
아주대학교산학협력단
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Application filed by 아주대학교산학협력단 filed Critical 아주대학교산학협력단
Publication of WO2019004748A2 publication Critical patent/WO2019004748A2/ko
Publication of WO2019004748A3 publication Critical patent/WO2019004748A3/ko
Publication of WO2019004748A9 publication Critical patent/WO2019004748A9/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/40—Disorders due to exposure to physical agents, e.g. heat disorders, motion sickness, radiation injuries, altitude sickness, decompression illness

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

본 발명은 페리오스틴(periostin)을 이용한 직업성 천식의 진단을 위한 정보제공 방법에 관한 것이다. 더욱 상세하게는 TDI에 노출된 집단의 혈액 내 페리오스틴 농도를 측정하는 단계를 포함하는 직업성 천식의 진단을 위한 정보제공 방법에 관한 것이다. 본 발명에 따르면, 혈액 내 페리오스틴 농도 측정을 통해 직업성 천식을 조기에 진단하고 치료함으로써 직업성 천식 환자의 예후를 향상시킬 수 있다.
PCT/KR2018/007348 2017-06-30 2018-06-28 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법 WO2019004748A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170083618A KR101967826B1 (ko) 2017-06-30 2017-06-30 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법
KR10-2017-0083618 2017-06-30

Publications (3)

Publication Number Publication Date
WO2019004748A2 WO2019004748A2 (ko) 2019-01-03
WO2019004748A3 true WO2019004748A3 (ko) 2019-03-28
WO2019004748A9 WO2019004748A9 (ko) 2019-05-16

Family

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Application Number Title Priority Date Filing Date
PCT/KR2018/007348 WO2019004748A2 (ko) 2017-06-30 2018-06-28 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법

Country Status (2)

Country Link
KR (1) KR101967826B1 (ko)
WO (1) WO2019004748A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102527520B1 (ko) 2020-09-16 2023-05-03 순천대학교 산학협력단 직업성 천식 진단용 조성물 및 이를 이용한 직업성 천식 진단방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100131003A (ko) * 2008-03-31 2010-12-14 제넨테크, 인크. 천식을 치료 및 진단하기 위한 조성물 및 방법
KR101114033B1 (ko) * 2009-04-10 2012-02-21 아주대학교산학협력단 단일염기다형을 포함하는 폴리뉴클레오티드, 이를 포함하는 마이크로어레이 및 진단키트, 및 이를 이용한 분석방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100131003A (ko) * 2008-03-31 2010-12-14 제넨테크, 인크. 천식을 치료 및 진단하기 위한 조성물 및 방법
KR101114033B1 (ko) * 2009-04-10 2012-02-21 아주대학교산학협력단 단일염기다형을 포함하는 폴리뉴클레오티드, 이를 포함하는 마이크로어레이 및 진단키트, 및 이를 이용한 분석방법

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
OH, SUNG SOO: "Occupational asthma in Korea", JOURNAL OF KOREAN MEDICAL SCIENCE, 2010, XP055586164 *
SHANSHAN ET AL.: "Levels and significance of serum periostin and Ig E in workers exposed to 6-APA, 7-ACA", CHINESE JOURNAL OF INDUSTRIAL MEDICINE, April 2017 (2017-04-01), pages 98 - 101, XP055586162 *
SIM, DA WOON ET AL.: "Biomarkers of adult asthma and personalized medicine", ALLERGY ASTHMA & RESPIRATORY DISEASE, vol. 4, no. 1, 2016, pages 4 - 13, XP055586179 *

Also Published As

Publication number Publication date
KR20190003117A (ko) 2019-01-09
WO2019004748A9 (ko) 2019-05-16
WO2019004748A2 (ko) 2019-01-03
KR101967826B1 (ko) 2019-04-11

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