WO2018235649A1

WO2018235649A1 - Charged particle beam therapy device and evaluation device

Info

Publication number: WO2018235649A1
Application number: PCT/JP2018/022208
Authority: WO
Inventors: 昌平水谷; 徹浅羽; 健二堀田; 大海馬場
Original assignee: 住友重機械工業株式会社; 国立研究開発法人国立がん研究センター
Priority date: 2017-06-19
Filing date: 2018-06-11
Publication date: 2018-12-27
Also published as: JP2020137532A

Abstract

A charged particle beam therapy device (1) comprises: an irradiation unit (103) which irradiates a charged particle beam emitted from an accelerator, on the basis of therapy plan information determined by a therapy plan device (70); a charged particle beam information acquisition unit (104) which acquires information relating to the charged particle beam irradiated from the irradiation unit (103); and a dose distribution computation unit (105) which, on the basis of the information relating to the charged particle beam due to the charged particle beam information acquisition unit (104), computes a dose distribution when a body to be irradiated is irradiated with the charged particle beam.

Description

Charged particle beam therapeutic apparatus and evaluation apparatus

The present invention relates to a charged particle beam therapy apparatus and an evaluation apparatus.

When irradiating charged particle beam such as a proton beam to the affected area of a patient by the charged particle beam therapy apparatus, the affected area is minimized while the charged area beam is appropriately irradiated to the affected area. Is required. Then, based on a treatment plan created based on a patient's CT image etc. beforehand, work called patient QA (Qualty Assurance) which confirms dose distribution of a charged particle beam is performed (for example, refer to patent documents 1). In the patient QA described in Patent Document 1, as a method of confirming the dose distribution of charged particle beams, a charged particle beam is irradiated to a homogeneous medium such as a water phantom that simulates the patient's body, and a dosimeter is used. The dose distribution is measured.

Japanese Patent Application Publication No. 2003-047666

However, although the above method can measure the dose distribution of the charged particle beam, it takes time and labor for setting a homogeneous medium simulating the patient's body, a dose meter for measuring the dose distribution, etc. It will be necessary. Further, as a method of measuring the dose distribution of the charged particle beam, it is conceivable to use on-line monitoring PET when irradiating the charged particle beam to the patient, but a large-scale measuring means is required. Thus, it is not easy to grasp the dose distribution of the charged particle beam actually irradiated in the charged particle beam therapy apparatus.

The present invention has been made in view of the above, and it is possible to obtain information related to the dose distribution of charged particle beams actually irradiated in the charged particle beam therapy apparatus by a simpler method, and It aims at providing an evaluation device.

In order to achieve the above object, a charged particle beam treatment apparatus according to an aspect of the present invention comprises: an irradiation unit that irradiates a charged particle beam emitted from an accelerator based on treatment plan information determined by the treatment planning apparatus; A charged particle beam is acquired based on a charged particle beam information acquiring unit that acquires information related to the charged particle beam irradiated from the irradiation unit, and information related to the charged particle beam acquired by the charged particle beam information acquiring unit. And a dose distribution calculating unit that calculates a dose distribution when the object to be irradiated is irradiated.

According to the above charged particle beam treatment apparatus, the charged particle beam information acquisition unit acquires information related to the charged particle beam irradiated from the irradiation unit based on the treatment plan information. Then, from the information on the charged particle beam to be irradiated, the dose distribution in the object to be irradiated when the charged particle beam is irradiated to the object to be irradiated can be calculated by the dose distribution calculation unit. Therefore, compared to the conventional method, the work such as setting of the irradiated object can be omitted, so that it relates to the dose distribution of the charged particle beam actually irradiated in the charged particle beam therapeutic apparatus by a simpler method. You can get information. In addition, it becomes possible to save the work related to the evaluation of the dose distribution of the charged particle beam when the charged particle beam is irradiated based on the treatment plan. The “subject to be irradiated” includes a patient to be treated by the charged particle beam treatment apparatus and a homogeneous medium such as a water phantom simulating the patient's body.

The dose distribution calculation unit is a matching rate between the calculation result of the dose distribution when the object is irradiated with the charged particle beam and the dose distribution of the object calculated based on the treatment plan information. Can be calculated.

As described above, the dose distribution calculation unit 105 matches the calculation result of the dose distribution at the time of irradiating the charged body with the charged particle beam and the dose distribution of the irradiated body calculated based on the treatment plan information. By setting the ratio to be calculated, it becomes possible to compare the dose distribution assumed in the treatment plan information with the dose distribution when actually irradiating a charged particle beam.

The dose distribution calculation unit is a matching rate between the calculation result of the dose distribution when the object is irradiated with the charged particle beam and the dose distribution of the object calculated based on the treatment plan information. It can be set as the aspect which performs evaluation which concerns on the said treatment plan information based on these.

With the above configuration, the dose distribution calculation unit 105 can also evaluate the treatment plan information based on the calculation result of the dose distribution, and the work relating to the evaluation of the dose distribution of the charged particle beam based on the treatment plan It is possible to save labor.

The charged particle beam information acquisition unit may be provided in the irradiation unit.

As described above, the configuration in which the charged particle beam information acquisition unit 104 is provided in the irradiation unit 103 eliminates the need for separately providing a measuring instrument or the like for acquiring information related to charged particle beams, which is simpler. By the device configuration, the work relating to the evaluation of the dose distribution of the charged particle beam based on the treatment plan can be saved. The provision of the charged particle beam information acquisition unit in the irradiation unit means that a part of the function as the charged particle beam information acquisition unit is provided in the irradiation unit.

The dose distribution calculating unit acquires a CT image related to the irradiated object acquired after the preparation of the treatment plan information, and the CT image and the charged particle beam acquired by the charged particle beam information acquiring unit The dose distribution when the charged particle beam is irradiated to the irradiation object can be calculated based on the information according to

As described above, based on the CT image and the information related to the charged particle beam acquired by the charged particle beam information acquisition unit, the dose distribution when the charged particle beam is irradiated to the irradiated object is calculated. Even when there is a change in the inside of the irradiated body or the like after the preparation of the treatment plan information, it is possible to appropriately calculate the dose distribution when the irradiated body is irradiated with the charged particle beam.

The irradiation unit irradiates the charged particle beam emitted from the accelerator from a plurality of directions, and the dose distribution of the charged particle beam in the plane is uneven in one of the plurality of directions. The charged particle beam information acquiring unit individually acquires information on charged particle beams irradiated from a plurality of directions in the irradiating unit, and the dose distribution calculating unit is acquired by the charged particle beam information acquiring unit. According to the information related to the charged particle beam, the dose distribution when the charged particle beam is irradiated to the irradiated object can be calculated for each irradiation direction of the irradiation unit.

With the above configuration, the irradiation unit irradiates the charged particle beam from a plurality of directions, and the dose distribution of the charged particle beam in the plane is uneven in one of the plurality of directions. However, in the dose distribution calculation unit, based on the information related to the charged particle beam acquired by the charged particle beam information acquisition unit, the dose distribution at the time of irradiating the charged particle beam to the irradiated object is determined for each irradiation direction of the irradiation unit. By setting it as the aspect calculated to, it is possible to obtain the information related to the dose distribution of the charged particle beam actually irradiated in the charged particle beam therapy apparatus in each irradiation direction by a simpler method.

The dose distribution calculation unit may calculate and display the sum of calculation results of dose distributions for each of a plurality of irradiation directions of the irradiation unit when the irradiation object is irradiated with the charged particle beam.

By having the above configuration, the result of the calculation of the dose distribution for each of the plurality of irradiation directions of the irradiation unit when the charged particle beam is irradiated to the irradiation object is displayed. The result of the summation of the calculation results of the dose distribution for each of the plurality of irradiation directions can be easily confirmed.

The evaluation device according to one aspect of the present invention acquires information related to the charged particle beam when irradiated with the charged particle beam from the irradiation unit of the charged particle beam therapy device based on the treatment plan information determined by the treatment planning device. Dose distribution calculation for calculating a dose distribution when the object to be irradiated is irradiated with the charged particle beam based on the charged particle beam information acquiring unit and the information on the charged particle beam acquired by the charged particle beam information acquiring unit Part.

According to the above-described evaluation apparatus, the charged particle beam information acquisition unit acquires information related to the charged particle beam irradiated from the irradiation unit of the charged particle beam therapy apparatus based on the treatment plan information. Then, from the information on the charged particle beam to be irradiated, the dose distribution in the object to be irradiated when the charged particle beam is irradiated to the object to be irradiated can be calculated by the dose distribution calculation unit. Therefore, compared to the conventional method, the work such as setting of the irradiated object can be omitted, so that it relates to the dose distribution of the charged particle beam actually irradiated in the charged particle beam therapeutic apparatus by a simpler method. You can get information. In addition, it becomes possible to save the work related to the evaluation of the dose distribution of the charged particle beam when the charged particle beam is irradiated based on the treatment plan.

According to the present invention, there are provided a charged particle beam therapy apparatus and an evaluation apparatus capable of obtaining information related to the dose distribution of charged particle beams actually irradiated in the charged particle beam therapy apparatus by a simpler method.

BRIEF DESCRIPTION OF THE DRAWINGS It is a schematic block diagram of the charged particle beam therapeutic apparatus which concerns on one Embodiment of this invention. It is a schematic block diagram of the irradiation part vicinity of the charged particle beam therapeutic apparatus of FIG. It is a block diagram explaining each function of a charged particle beam therapy system. It is a figure explaining the evaluation method in charged particle beam therapy equipment. It is a flow figure showing the 1st application of calculation of dose distribution using irradiation log information. It is a flow figure showing the 2nd application of calculation of dose distribution using irradiation log information. It is a flow figure showing calculation of dose distribution using irradiation log information.

Hereinafter, with reference to the accompanying drawings, modes for carrying out the present invention will be described in detail. In the description of the drawings, the same elements will be denoted by the same reference symbols, without redundant description.

First, with reference to FIG. 1 and FIG. 2, a mechanism relating to irradiation of charged particle beams in the charged particle beam therapy system 1 according to an embodiment of the present invention will be described. As shown in FIG. 1, the charged particle beam therapeutic apparatus 1 is an apparatus used for cancer treatment by radiation therapy, etc., and accelerates charged particles generated by an ion source (not shown) to be used as a charged particle beam. An accelerator 3 for emitting light, an irradiation unit 2 for irradiating a charged particle beam to an irradiation object, and a beam transport line 41 for transporting a charged particle beam emitted from the accelerator 3 to the irradiation unit 2 are provided. The irradiation unit 2 is attached to a rotating gantry 5 provided so as to surround the treatment table 4. The irradiation unit 2 is rotatable around the treatment table 4 by a rotating gantry 5.

FIG. 2 is a schematic configuration view of the vicinity of an irradiation unit of the charged particle beam therapy system of FIG. In the following description, the terms “X direction”, “Y direction”, and “Z direction” are used. The “Z direction” is a direction in which the base axis AX of the charged particle beam B extends, and is a depth direction of irradiation of the charged particle beam B. The “base axis AX” is the irradiation axis of the charged particle beam B when not deflected by the scanning electromagnet 6 described later. FIG. 2 shows that the charged particle beam B is irradiated along the base axis AX. The “X direction” is one direction in a plane orthogonal to the Z direction. The “Y direction” is a direction orthogonal to the X direction in a plane orthogonal to the Z direction.

First, the schematic configuration of the charged particle beam therapy system 1 according to the present embodiment will be described with reference to FIG. The charged particle beam therapy apparatus 1 is an irradiation apparatus related to a scanning method. The scanning method is not particularly limited, and line scanning, raster scanning, spot scanning or the like may be employed. Moreover, it is not limited to a scanning system, Other irradiation systems (for example, laminated body irradiation method) may be adopted. As shown in FIG. 2, the charged particle beam therapy system 1 includes an accelerator 3, an irradiation unit 2, a beam transport line 41, and a control unit 7.

The accelerator 3 is a device that accelerates charged particles and emits a charged particle beam B of preset energy. Examples of the accelerator 3 include a cyclotron, a synchrotron, a synchrocyclotron, a linac and the like. In addition, when adopting the cyclotron which radiate | emits the charged particle beam B of predetermined energy as the accelerator 3, the energy of the charged particle beam B sent to the irradiation part 2 is employ | adopted by employ | adopting the energy adjustment part 20 (refer FIG. 1). Can be adjusted (decreased). In addition, since the synchrotron can easily change the energy of the charged particle beam B to be emitted, when the synchrotron is adopted as the accelerator 3, the energy adjusting unit 20 may be omitted. The accelerator 3 is connected to the control unit 7, and the supplied current is controlled. The charged particle beam B generated by the accelerator 3 is transported to the irradiation nozzle 9 by the beam transport line 41. The beam transport line 41 connects the accelerator 3, the energy adjustment unit 20, and the irradiation unit 2, and transports the charged particle beam B emitted from the accelerator 3 to the irradiation unit 2.

The charged particle beam treatment apparatus 1 is disposed in the accelerator 3 and blocks the charged particle beam B emitted from the ion source to stop the emission of the charged particle beam B from the accelerator 3 (non-irradiation). It has 16 more. It is to be noted that means other than the beam chopper may be used as means for switching between irradiation and non-irradiation of charged particle beams. For example, a shutter may be provided in the beam transport line and the shutter may block the charged particle beam. Alternatively, the charged particle beam may be emitted from the accelerator 3 only when the charged particle beam is irradiated using a deflector (electrode) provided in the accelerator 3.

The irradiation unit 2 irradiates the charged particle beam B to the tumor 14 in the body of the patient 15 (irradiated body). The charged particle beam B is obtained by accelerating a charged particle at high speed, and examples thereof include a proton beam, a heavy particle (heavy ion) beam, an electron beam and the like. Specifically, the irradiation unit 2 is a device for irradiating the tumor 14 with the charged particle beam B emitted from the accelerator 3 that accelerates charged particles generated by the ion source (not shown) and transported by the beam transport line 41. . The irradiation unit 2 includes a scanning electromagnet 6, a quadrupole electromagnet 8, a profile monitor 11, a dose monitor 12, flatness monitors 13 a and 13 b, and a degrader 30. The scanning electromagnet 6, the

monitors

11, 12, 13 a and 13 b, the quadrupole electromagnet 8, and the degrader 30 are accommodated in the irradiation nozzle 9. The quadrupole electromagnet 8, the profile monitor 11, the dose monitor 12, the flatness monitors 13a and 13b, and the degrader 30 may be omitted.

The scanning electromagnet 6 includes an X-direction scanning electromagnet 6 a and a Y-direction scanning electromagnet 6 b. The X-direction scanning electromagnet 6a and the Y-direction scanning electromagnet 6b are each composed of a pair of electromagnets, and change the magnetic field between the pair of electromagnets according to the current supplied from the control unit Scan line B The X-direction scanning electromagnet 6a scans the charged particle beam B in the X direction, and the Y-direction scanning electromagnet 6b scans the charged particle beam B in the Y direction. The scanning electromagnets 6 are disposed on the base axis AX and downstream of the charged particle beam B with respect to the accelerator 3 in this order.

The quadrupole electromagnet 8 includes an X-direction quadrupole electromagnet 8a and a Y-direction quadrupole electromagnet 8b. The X-direction quadrupole electromagnet 8 a and the Y-direction quadrupole electromagnet 8 b squeeze and converge the charged particle beam B according to the current supplied from the control unit 7. The X direction quadrupole electromagnet 8 a converges the charged particle beam B in the X direction, and the Y direction quadrupole electromagnet 8 b converges the charged particle beam B in the Y direction. The beam size of the charged particle beam B can be changed by changing the current supplied to the quadrupole electromagnet 8 to change the throttling amount (convergence amount). The quadrupole electromagnet 8 is disposed on the base axis AX and between the accelerator 3 and the scanning electromagnet 6 in this order. The beam size is the size of the charged particle beam B in the XY plane. The beam shape is the shape of the charged particle beam B in the XY plane.

The profile monitor 11 detects the beam shape and position of the charged particle beam B for alignment at the time of initial setting. The profile monitor 11 is disposed on the base axis AX and between the quadrupole electromagnet 8 and the scanning electromagnet 6. The dose monitor 12 (charged particle beam information acquisition unit) detects the intensity of the charged particle beam B. The dose monitor 12 is disposed on the base axis AX and downstream of the scanning electromagnet 6. The flatness monitors 13a and 13b detect and monitor the beam shape and position of the charged particle beam B. The flatness monitors 13 a and 13 b are disposed on the base axis AX and downstream of the charged particle beam B with respect to the dose monitor 12. Each of the

monitors

11, 12, 13a, 13b outputs the detected detection result to the control unit 7. The control unit 7 has a function of managing detection results from the dose monitor 12, and thus has a part of a function as a charged particle beam information acquisition unit described later.

The degrader 30 reduces the energy of the passing charged particle beam B to finely adjust the energy of the charged particle beam B. In the present embodiment, the degrader 30 is provided at the tip 9 a of the irradiation nozzle 9. The tip 9 a of the irradiation nozzle 9 is the end on the downstream side of the charged particle beam B.

The control unit 7 includes, for example, a CPU, a ROM, and a RAM. The control unit 7 controls the accelerator 3, the scanning electromagnet 6, and the quadrupole electromagnet 8 based on the detection results output from the

monitors

11, 12, 13a, 13b.

In addition, the charged particle beam therapy system 1 is connected to a treatment planning system 70 (see FIG. 3) which performs a treatment plan for charged particle beam therapy. The treatment planning device 70 measures the tumor 14 of the patient 15 by CT or the like before treatment, and plans the dose distribution (dose distribution of charged particle beam to be irradiated) at each position of the tumor 14. Specifically, the treatment planning device 70 creates treatment plan information that is a treatment plan for the tumor 14. The treatment planning device 70 transmits the created treatment plan information to the control unit 7.

When performing irradiation of charged particle beams by the scanning method, the tumor 14 is virtually divided into a plurality of layers in the Z direction, and in one layer, the charged particle beams are scanned so as to follow the scanning path defined in the treatment planning information. Irradiate. Then, after the irradiation of the charged particle beam in the one layer is completed, the charged particle beam in the next adjacent layer is irradiated.

When the charged particle beam B is irradiated by the scanning method by the charged particle beam treatment apparatus 1 shown in FIG. 2, the quadrupole electromagnet 8 is brought into an operating state (ON) so that the passing charged particle beam B converges.

Subsequently, the charged particle beam B is emitted from the accelerator 3. The emitted charged particle beam B is scanned by the control of the scanning electromagnet 6 so as to follow the scanning path defined in the treatment plan information. As a result, the charged particle beam B is irradiated while being scanned within the irradiation range of one layer set in the Z direction with respect to the tumor 14. When the irradiation of one layer is completed, the charged particle beam B is irradiated to the next layer.

Here, in the case where the patient is treated using the charged particle beam treatment apparatus 1, the dose distribution in the patient's body is obtained when the irradiation is performed along the treatment plan information created in the treatment planning apparatus 70. It is necessary to verify before treatment that the treatment plan information is as expected. Regarding the treatment plan information, settings relating to the irradiation of the charged particle beam to the patient are determined so as to minimize the influence (side effects) on the surrounding normal tissues while maximizing the irradiation effect on the patient's tumor 14. The treatment plan information is created on the assumption that the charged particle beam treatment apparatus 1 can appropriately irradiate the charged particle beam to a desired position, but the desired position is determined according to the characteristics of the charged particle beam treatment apparatus. It is also possible that the dose distribution according to the treatment plan information can not be obtained by irradiating the charged particle beam at a position or intensity different from that of the above. Therefore, the dose distribution of the charged particle beam in the homogeneous medium at the time of irradiating the charged particle beam by the charged particle beam treatment apparatus 1 to the homogeneous medium (for example, water phantom etc.) simulating the patient in advance is measured Verify that the dose distribution is as expected in the planning information. This work is called patient QA. However, in the conventional method of patient QA, setting of a homogeneous medium simulating the patient (a task of preparing a water phantom and setting it at the tip of the irradiation nozzle 9), and placing it in the water phantom to measure the dose distribution It takes time to set up the dosimeter used. Also, when measuring the dose distribution, after measuring the dose distribution at a certain position in the depth direction (Z direction) of the water phantom, the dosimeter is moved to the next measurement position along the depth direction (Z direction) Repeat moving and measuring. Therefore, the conventional method of patient QA has a problem that the required time increases (for example, it takes about 1 to 2 hours). Since the charged particle beam treatment apparatus 1 is occupied while performing patient QA, the usage time of the charged particle beam treatment apparatus 1 for treatment of one patient increases. Therefore, the number of patients that can be treated by one charged particle beam therapy system 1 is reduced, which directly leads to a decrease in operation efficiency.

Therefore, in the charged particle beam treatment apparatus 1 according to the present embodiment, instead of irradiating the charged particle beam by setting the homogeneous medium (irradiated body), the charged particle beam is irradiated without arranging the homogeneous medium. . Also, instead of measuring (measuring) the dose distribution in the homogeneous medium using a dosimeter disposed in the homogeneous medium, measurement is performed on the charged particle beam irradiated from the charged particle beam therapy system 1. Then, from the information related to the charged particle beam to be irradiated, the dose distribution in the homogeneous medium assumed to be obtained when the homogeneous particle medium is irradiated with the charged particle beam is calculated by calculation. In addition, the dose distribution obtained as a result of the calculation is compared with the dose distribution in the treatment plan information to evaluate whether the charged particle beam can be irradiated to the patient according to the treatment plan information (whether the treatment can be performed) .

Therefore, as shown in FIG. 3, the charged particle beam therapeutic apparatus 1 according to the present embodiment includes a communication unit 101, a control unit 102, an irradiation unit 103, a charged particle beam information acquisition unit 104, and a dose distribution calculation unit 105. .

The communication unit 101 has a function of communicating with the treatment planning device 70 and acquiring treatment planning information from the treatment planning device 70. The acquired treatment plan information is sent to the control unit 102.

The control unit 102 controls the irradiation unit 103 to perform irradiation of the charged particle beam based on the treatment plan information. Also, information related to charged particle beams measured or acquired in the charged particle beam information acquisition unit 104 is acquired. The information on the charged particle beam acquired by the control unit 102 and the treatment plan information are sent to the dose distribution calculation unit 105. The control unit 102 corresponds to the control unit 7 shown in FIG.

The irradiation unit 103 has a function of irradiating a charged particle beam at a predetermined setting based on an instruction from the control unit 7. The irradiation unit 103 corresponds to the irradiation unit 2 described in FIGS. 1 and 2.

The charged particle beam information acquisition unit 104 has a function of acquiring information related to a charged particle beam irradiated from the charged particle beam treatment apparatus 1 to a patient. The information on the charged particle beam acquired by the charged particle beam information acquisition unit 104 includes information on the intensity, the position, and the energy of the charged particle beam emitted from the irradiation nozzle 9 at a predetermined setting. . In the present embodiment, in the dose monitor 12 and the flatness monitors 13a and 13b in the irradiation nozzle 9 shown in FIG. 2, information on the intensity and position of the charged particle beam is acquired. Therefore, the dose monitor 12 and the flatness monitors 13a and 13b have a function as the charged particle beam information acquisition unit 104. That is, at least a part of the function of the charged particle beam information acquisition unit 104 is disposed in the irradiation nozzle 9 included in the irradiation unit 103.

Moreover, the information which concerns on energy among the information which concerns on a charged particle beam is information contained in treatment plan information. In the charged particle beam treatment apparatus 1, the control unit 7 relates to information concerning the position, intensity, beam size, etc. of the charged particle beam acquired in the dose monitor 12 and the

flatness monitor

13a, 13b, and energy contained in the treatment plan information. Information and may be collectively managed as "irradiation log information". Therefore, the charged particle beam information acquisition unit 104 may be configured to acquire irradiation log information including information related to charged particle beams. The irradiation log information is created by the control unit 7 by collecting information acquired in the dose monitor 12 and the flatness monitors 13a and 13b and information included in the treatment plan information. Therefore, the control unit 7 also has a part of the function as the charged particle beam information acquisition unit 104.

The dose distribution calculation unit 105 determines the dose in the homogeneous medium when the homogeneous particle (irradiated body) is irradiated with the charged particle beam from the information on the charged particle beam obtained by the charged particle beam information acquisition unit 104. It has a function to calculate the distribution. When calculating the dose distribution, when the charged particle beam is irradiated to the homogeneous medium, it is calculated what path the charged particle beam follows and which depth in the homogeneous medium is reached. It may be calculated by simulation how the intensity of the charged particle beam changes as it travels through the homogeneous medium (how much the dose of the charged particle beam reaches the predetermined position), The method is not particularly limited.

Further, the dose distribution calculation unit 105 has a function of comparing the calculation result of the dose distribution based on the information on the charged particle beam obtained by the charged particle beam information acquisition unit 104 with the dose distribution based on the treatment plan information. The dose distribution assumed to be obtained when the charged particle beam is irradiated based on the treatment plan information can be calculated from the treatment plan information. Therefore, the dose distribution calculation unit 105 compares the dose distribution calculated based on the treatment plan information with the dose distribution calculated from the information related to the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1. Match rate is calculated. By calculating the coincidence rate in this manner, it can be verified whether the irradiation of the charged particle beam assumed by the charged particle beam treatment apparatus 1 realizes the irradiation of the charged particle beam assumed in the treatment plan information.

In the dose distribution calculation unit 105, the dose distribution calculated based on the treatment plan information was compared with the dose distribution calculated from the information related to the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1. It is good also as composition which performs some evaluation based on a result. For example, in the dose distribution calculation unit 105, the matching rate between the dose distribution calculated based on the treatment plan information and the dose distribution calculated from the information related to the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1. The treatment plan information may be evaluated based on the above. In addition, in the dose distribution calculation unit 105, based on the above matching rate, it is determined whether the charged particle beam can be irradiated to the patient based on the treatment plan information (whether or not the treatment based on the treatment plan information can be performed) It may be configured to

The operator of the charged particle beam treatment apparatus 1 outputs the result calculated by the dose distribution calculation unit 105, the evaluation result in the case of evaluation, and the like to the outside by an output unit (not shown) or the like. The results can be confirmed.

Next, a specific procedure of evaluation of the dose distribution (patient QA) in the above-described charged particle beam therapy system 1 will be described with reference to FIG.

First, in the communication unit 101, the charged particle beam treatment apparatus 1 acquires information (treatment plan information) related to a treatment plan from the treatment planning apparatus 70 (S01). Based on the treatment plan information, in the charged particle beam treatment apparatus 1, first, the dose distribution in the homogeneous medium (irradiated body) when the charged particle beam is irradiated based on the treatment plan information in the dose distribution calculation unit 105. Calculation of (S02). In addition, the dose distribution at the time of irradiating a charged particle beam based on this treatment plan information may be calculated beforehand by the treatment planning apparatus 70. In that case, in the charged particle beam therapy system 1, it is only necessary to obtain the calculation result from the treatment planning system 70 and hold it in the dose distribution calculation unit 105. That is, calculation (S02) of dose distribution based on treatment plan information can be omitted.

Further, in the charged particle beam treatment apparatus 1, the irradiation unit 103 irradiates the charged particle beam under the control of the control unit 102 based on the treatment plan information. Then, in the charged particle beam information acquisition unit 104 of the charged particle beam therapy apparatus 1, the irradiation unit 103 acquires information related to the charged particle beam when irradiated with the charged particle beam. Here, irradiation log information is acquired as information related to charged particle beams (S03). Next, the dose distribution calculation unit 105 calculates the dose distribution in the homogeneous medium based on the irradiation log information (information related to the charged particle beam) (S04).

Calculation of dose distribution in homogeneous medium based on treatment plan information (S02), acquisition of radiation log information (S03) and calculation of dose distribution in homogeneous medium based on this information (S04) are independent of each other To be done. Therefore, which one may go first.

Thereafter, the dose distribution calculation unit 105 compares the dose distribution calculated based on the treatment plan information with the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1, A match rate is calculated (S05). The coincidence rate can be calculated using, for example, gamma analysis or the like, but is not limited to this.

Furthermore, the dose distribution calculation unit 105 may evaluate the treatment plan information itself as necessary (S06). As the evaluation here, for example, the matching rate between the dose distribution calculated based on the above-mentioned treatment plan information and the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1 If the value is equal to or more than a predetermined value, treatment based on the treatment plan information may be performed in the charged particle beam treatment apparatus 1 (if the matching rate is smaller than the predetermined value, the treatment based on the treatment plan information is performed. However, the determination is not limited to this.

Thus, a series of processes related to the evaluation of the dose distribution (patient QA) in the charged particle beam therapy system 1 is completed.

As described above, according to the charged particle beam therapy system 1 according to the present embodiment, the information related to the charged particle beam irradiated from the irradiation unit 103 is acquired by the charged particle beam information acquisition unit 104. Then, from the information on the charged particle beam to be irradiated, the dose distribution calculation unit 105 calculates the dose distribution in the homogeneous medium when the homogeneous particle is irradiated with the charged particle beam. Therefore, as in the prior art, setting a homogeneous medium such as a water phantom and a dosimeter etc. for measurement of the dose distribution, as compared to the case where the dose distribution is measured by irradiating charged particle beams, And the work at the time of measurement can be omitted. Therefore, according to the charged particle beam therapeutic apparatus 1, it is possible to obtain information related to the dose distribution of the charged particle beam actually irradiated in the charged particle beam therapeutic apparatus by a simpler method, and based on the treatment plan It becomes possible to save the work concerning the evaluation of the dose distribution of the charged particle beam in the case of irradiating a line. Specifically, in the conventional method, the required time for a series of operations relating to the evaluation of the dose distribution of the charged particle beam was about 1 to 2 hours, but according to the charged particle beam therapy system 1 according to the present embodiment The required time can be greatly reduced to several minutes.

In the above-described charged particle beam therapy system, the dose distribution calculation unit 105 calculates the dose distribution when the charged particle beam is irradiated to the irradiated body (homogeneous medium) and the calculation is based on the treatment plan information. The matching rate with the dose distribution in the irradiated body (homogeneous medium) is calculated. By thus calculating the matching rate in the dose distribution calculation unit 105, it is possible to compare the dose distribution assumed in the treatment plan information with the dose distribution when actually irradiating a charged particle beam. It becomes.

Furthermore, in the dose distribution calculation unit 105, the calculation result of the dose distribution when the charged particle beam is irradiated to the irradiated body (homogeneous medium) and the irradiated body (homogeneous medium) calculated based on the treatment plan information If the evaluation regarding the treatment plan information is performed based on the matching rate of the dose distribution, the dose distribution calculation unit 105 can also evaluate the treatment plan information, and charge based on the treatment plan It becomes possible to save the work concerning the evaluation of the dose distribution of particle beam.

Further, in the charged particle beam therapy system 1, a part of the charged particle beam information acquisition unit 104 that acquires information related to charged particle beams is provided in the irradiation unit 103. In the case of the charged particle beam therapy system 1, the dose monitor 12 and the flatness monitors 13 a and 13 b in the irradiation nozzle 9 function as the charged particle beam information acquisition unit 104. As described above, the configuration in which the charged particle beam information acquisition unit 104 is provided in the irradiation unit 103 eliminates the need to separately provide a measuring device or the like for acquiring information related to the charged particle beam. In particular, when the monitor used for controlling the irradiation unit 103 by the control unit 7 is used as the charged particle beam information acquisition unit 104 as in the charged particle beam therapy apparatus 1, information related to charged particle beams is acquired. It is possible to acquire information without providing new facilities and the like.

Next, as in the case of the evaluation (patient QA) of the dose distribution using the charged particle beam treatment apparatus 1 described in the above embodiment, a method of utilizing the calculation of the dose distribution using the irradiation log information will be described. First, the first usage will be described with reference to FIG. As described above, in the charged particle beam therapy apparatus, information related to the charged particle beam irradiated from the irradiation unit 103 is acquired by the charged particle beam information acquisition unit 104, and the charged particle beam is irradiated from the information. The dose distribution in the object to be irradiated in the case of irradiating the light is calculated by the dose distribution calculation unit 105. The evaluation can be performed after the charged particle beam is irradiated to the patient by the charged particle beam treatment apparatus 1 using this method.

As a premise, in the charged particle beam treatment apparatus 1, the irradiation unit 103 irradiates a charged particle beam under the control of the control unit 102 based on the treatment plan information acquired from the treatment planning apparatus 70. Then, in the charged particle beam information acquisition unit 104 of the charged particle beam therapy apparatus 1, the irradiation unit 103 acquires information related to the charged particle beam when irradiated with the charged particle beam. Here, irradiation log information is acquired as information related to charged particle beams. These procedures are the same as the procedures (S01, S03) described above.

Next, in the communication unit 101, the charged particle beam therapy system 1 acquires a CT image of the patient on the treatment day (day when the patient is irradiated with the charged particle beam) (S11). The CT image of the patient on the treatment day can be imaged, for example, using a CT apparatus provided in an irradiation room or other room that irradiates a charged particle beam to the patient. In the charged particle beam therapy system 1, image data relating to a CT image of a patient is acquired from a device that has captured a CT image of the patient. Note that the timing of imaging of a CT image and acquisition by the charged particle beam therapy apparatus 1 may be timing prior to irradiation of a charged particle beam in the irradiation unit 103. Further, the CT image may be at least an image at the time of creation of the treatment plan, but the accuracy of the dose distribution calculation can be enhanced by using an image of a treatment day or a similar day.

Next, the dose distribution calculation unit 105 calculates the dose distribution of the charged particle beam in the patient's body based on the irradiation log information (information related to the charged particle beam) (S12). At this time, the dose distribution calculation unit 105 calculates the dose distribution using the irradiation log information and the CT image (image data) of the patient on the treatment day acquired in the previous step.

Thereafter, in the dose distribution calculation unit 105, the dose distribution of the charged particle beam in the patient assumed in the treatment plan information, and the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1 In comparison, the contents of irradiation of the charged particle beam by the charged particle beam therapy system 1 are evaluated (S13). Specifically, the matching rate of the dose distribution of the charged particle beam in the patient assumed in the treatment plan information and the dose distribution of the charged particle beam actually irradiated to the patient on the treatment day is evaluated.

As described above, the irradiation content of the charged particle beam can be evaluated using the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam therapy system 1. There is no means for measuring the dose distribution in the patient's body when performing charged particle beam therapy based on treatment plan information in real time. Therefore, conventionally, it has been calculated by calculation based on the CT image of the patient on the day of the treatment day and the irradiation condition of the charged particle beam specified in the treatment plan information. However, since the information related to the charged particle beam actually irradiated to the patient is not used, there is room for improvement in terms of credibility. On the other hand, as described above, the dose distribution of the charged particle beam is more accurately evaluated by calculating the dose distribution from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1. Can.

Further, with the above configuration, the information of the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam therapy apparatus 1 is an evaluation in the case where a trouble or the like of the charged particle beam therapy apparatus 1 occurs. It is also useful. For example, in the case where there is some trouble in the charged particle beam treatment apparatus 1 and the charged particle beam is irradiated under the irradiation condition different from the assumed irradiation condition, the charged particle beam treatment apparatus 1 is actually irradiated. The dose distribution calculated from the charged particle beam is considered to be different from the dose distribution based on the treatment plan information. Therefore, by comparing the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1 with the dose distribution based on the treatment plan information, the dose derived from the trouble etc. on the apparatus side It is also possible to evaluate how the distribution has changed, and to appropriately evaluate the influence on the patient.

Furthermore, the above-mentioned method is considered to be particularly useful when the irradiation of the charged particle beam is repeated a plurality of times. As described above, since there is no means for measuring the dose distribution in the patient's body in real time when the charged particle beam is irradiated based on the treatment plan information, when the charged particle beam irradiation is repeated multiple times, It is also impossible to evaluate how the dose distribution in the patient's body for each irradiation cycle is. In addition, when irradiation of charged particle beams is repeated a plurality of times in such a state, the dose distribution in the patient's body in integration by irradiation of the charged particle beams a plurality of times is that of the charged particle beam specified in the treatment plan information. It may be different from the calculation result of dose distribution based on irradiation conditions. On the other hand, according to the above-mentioned method, since the dose distribution can be calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1, the dose distribution in the patient's body for each irradiation cycle The calculation can be appropriately performed, and it becomes possible to accurately evaluate the dose distribution in the patient's body by integration by multiple irradiation of charged particle beams.

Next, a second application of the calculation of dose distribution using the irradiation log information will be described with reference to FIG. In the second utilization method, as described above, in the charged particle beam therapy apparatus, information related to the charged particle beam irradiated from the irradiating unit 103 is acquired by the charged particle beam information acquiring unit 104, and the information is obtained from the information. The charged particle beam treatment apparatus 1 irradiates a patient with a charged particle beam by using the method of calculating the dose distribution in the irradiated body in the case of irradiating the charged particle beam to the irradiated body by the dose distribution calculation unit 105 by calculation. Before doing this, it is possible to evaluate the necessity of recalculation of the treatment plan.

Next, in the communication unit 101, the charged particle beam therapy system 1 acquires a CT image of the patient on the treatment day (the day when the patient is irradiated with the charged particle beam) (S21). In the charged particle beam therapy system 1, image data relating to a CT image of a patient is acquired from a device that has captured a CT image of the patient.

Next, the dose distribution calculation unit 105 calculates the dose distribution of the charged particle beam in the patient's body based on the irradiation log information (information related to the charged particle beam) (S22). At this time, the dose distribution calculation unit 105 calculates the dose distribution using the irradiation log information and the CT image (image data) of the patient on the treatment day acquired in the previous step. The irradiation log information used to calculate the dose distribution may be in the form of using the latest one. That is, the radiation log information of the treatment day (the day when the patient is irradiated with the charged particle beam) or a day closer thereto is used to calculate the dose distribution.

Thereafter, in the dose distribution calculation unit 105, the dose distribution of the charged particle beam in the patient assumed in the treatment plan information, and the dose distribution of the charged particle beam calculated using the irradiation log information of the charged particle beam treatment apparatus 1; Are compared to evaluate whether it is necessary to recalculate the treatment plan information used to treat the patient (S23). Specifically, the matching rate of the dose distribution of the charged particle beam in the patient assumed in the treatment plan information and the dose distribution of the charged particle beam when actually irradiated to the patient on the treatment day is evaluated. .

In this way, it is possible to use the dose distribution calculated from the actually irradiated charged particle beam of the charged particle beam therapy system 1 to evaluate whether recalculation of the treatment plan information is necessary. The arrangement of tissue in the patient's body changes little by little depending on the day. Therefore, correction or the like of the treatment plan information based on the CT image of the patient on that day is appropriately performed. However, until now, a comparison was made between the CT image of the patient on that day and the CT image of the patient before the start of treatment (eg, at the time of treatment planning information creation), to determine whether correction of the treatment plan information is necessary. It was done based on the results. On the other hand, it has not been evaluated how much the dose distribution in the patient's body changes from what was assumed in the treatment plan information when the charged particle beam is irradiated without correcting the treatment plan information, It was unclear to what extent the evaluation result of the necessity of recalculation of the treatment plan information affected the dose distribution in the patient's body irradiated with the charged particle beam. On the other hand, as described above, the radiation distribution information is calculated using the irradiation log information of the charged particle beam most recently irradiated by the charged particle beam treatment apparatus 1, thereby following the treatment plan information. Since the dose distribution in the patient's body when the patient is irradiated with the charged particle beam can be evaluated, whether to recalculate the treatment plan information as compared to the case of evaluating based on the patient's CT image It can be judged appropriately.

Next, a third application of the dose distribution calculation using the irradiation log information will be described with reference to FIG. In the third application, it is assumed that the irradiation method of the charged particle beam in the charged particle beam treatment apparatus 1 is a scanning irradiation method, and in particular, intensity modulated particle therapy (IMPT). In IMPT, among the dose distributions of charged particle beams irradiated from each irradiation direction (gate), the dose distribution of charged particle beams from at least one direction (gate) is made uneven in the plane. Moreover, the dose distribution of the charged particle beam irradiated from each irradiation direction (gate) may be made uneven respectively. As a third application, a method of using irradiation log information in the patient QA in the charged particle beam therapy system 1 adopting such IMPT will be described.

Conventionally, as the irradiation method of the charged particle beam in the charged particle beam therapy apparatus 1, SFUD (Single Field Uniform Dose) in which the dose distribution of the charged particle beam irradiated from each gate is uniform is often used. On the other hand, in IMPT, the charged particle beam irradiated in each gate is uneven. With such a configuration, for example, it is possible to reduce the irradiation dose of the charged particle beam to the area other than the tumor while making the dose distribution to the tumor in the patient to be treated uniform. That is, since the irradiation dose of the charged particle beam to the area other than the tumor can be suppressed, it is a method capable of reducing the influence on the patient.

In the IMPT, as described above, when the irradiation of charged particle beams from each portal is properly performed, the treatment of the treatment is performed so that the dose distribution of the tumor part becomes uniform when the charged particle beam doses from each portal are summed up. As a plan, dose distribution of charged particle beam at each gate is set. However, with regard to patient QA for IMPT, evaluation can not be performed in a state in which the doses of charged particle beams from each portal are summed up, and there is room for improvement. Specifically, the dose distribution of the charged particle beam from each portal is similar to the patient QA in SUFD, with respect to a homogeneous medium (for example, water phantom etc.) simulating the patient in advance. It can carry out by measuring the dose distribution of the charged particle beam in the homogeneous medium at the time of irradiation with the charged particle beam. However, it is difficult to evaluate what kind of dose distribution it will be when combining irradiation of charged particle beams from each portal.

In IMPT, the dose of each particle is set so that the irradiation dose of the charged particle beam to the non-tumor area is small while the dose distribution of the tumor part is made uniform. The difference in irradiation dose in the region of () becomes large (the dose distribution becomes steep). In other words, if the dose distribution is slightly deviated, high-dose charged particle beams may be irradiated to the area other than the tumor. Therefore, it is originally required to perform patient QA with higher accuracy, but as described above, evaluation of what kind of dose distribution will result when combined irradiation of charged particle beams from each portal is performed Could not do enough.

On the other hand, by using the irradiation log information of the charged particle beam by the charged particle beam treatment apparatus 1 described in the above embodiment, the dose distribution of the charged particle beam in each gate is calculated and the results are combined, It becomes possible to evaluate the dose distribution when the irradiation of charged particle beams from each gate is combined.

A specific procedure of evaluation of the dose distribution (patient QA) in the charged particle beam therapy system 1 for performing IMPT will be described with reference to FIG.

First, in the communication unit 101, the charged particle beam therapeutic apparatus 1 acquires information (treatment plan information) related to a treatment plan from the treatment planning apparatus 70 (S31). Based on the treatment plan information, in the charged particle beam treatment apparatus 1, first, the dose distribution in the irradiated body (homogeneous medium) when the charged particle beam is irradiated based on the treatment plan information in the dose distribution calculation unit 105. Calculation of (S32). The calculation of the dose distribution is performed for each portal (irradiation direction). That is, the charged particle beam information acquiring unit individually acquires information on charged particle beams irradiated from a plurality of directions in the irradiating unit, and the dose distribution calculating unit 105 calculates the dose distribution for each irradiation direction.

Further, in the charged particle beam treatment apparatus 1, the irradiation unit 103 irradiates the charged particle beam under the control of the control unit 102 based on the treatment plan information. Then, in the charged particle beam information acquisition unit 104 of the charged particle beam therapy apparatus 1, the irradiation unit 103 acquires information related to the charged particle beam when irradiated with the charged particle beam. Here, irradiation log information is acquired as information related to charged particle beams (S33). Next, in the dose distribution calculation unit 105, the dose distribution in the homogeneous medium is calculated based on the irradiation log information (information related to the charged particle beam) (S34). The calculation of the dose distribution is performed for each portal (irradiation direction). Furthermore, the dose distribution in the homogeneous medium at each gate is combined with the calculation results to calculate the total of the dose distribution when the charged particle beam is irradiated from all the gates (S35). The calculation results (S34, S35) can be displayed on a monitor or the like. With such a configuration, the operator of the apparatus can quickly confirm the result, and the convenience is enhanced.

Calculation of dose distribution in homogeneous medium based on treatment plan information (S32), acquisition of irradiation log information (S33), calculation of dose distribution in homogeneous medium based on this information (S34) and total dose distribution The calculation of (S35) is performed independently of each other. Therefore, which one may go first.

Thereafter, based on the dose distribution calculated based on the treatment plan information and the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1 in the dose distribution calculation unit 105, the treatment is performed. The plan is evaluated (S36). As the evaluation here, for example, the coincidence rate between the dose distribution calculated based on the treatment plan information and the dose distribution calculated from the charged particle beam actually irradiated by the charged particle beam treatment apparatus 1 is It can be calculated for each analysis and evaluated for each gate. In addition, it is evaluated whether the obtained dose distribution matches the dose distribution for the tumor assumed in the treatment plan, etc. as a result of calculation of the total dose distribution (S35) when the charged particle beam is irradiated from all fields. It can be carried out. The evaluation result (S36) may also be displayed on a monitor or the like. In addition, the dose distribution calculation unit 105 may evaluate the treatment plan information itself as necessary.

Thus, a series of processes related to the evaluation of the dose distribution (patient QA) in the charged particle beam therapy system 1 using IMPT is completed.

Thus, in the charged particle beam therapy system 1 using IMPT, the dose distribution of the charged particle beam at each gate is calculated using the irradiation log information of the charged particle beam, and the results are combined to obtain each gate. It is possible to evaluate the dose distribution in the case of combining the irradiation of the charged particle beam from. With such a configuration, not only labor saving work relating to the evaluation of dose distribution in the case of irradiating the charged particle beam based on the treatment plan but also when the irradiation of the charged particle beam from each portal is combined Assessing the dose distribution of B. can improve the accuracy of patient QA.

In particular, the configuration allows the user of the apparatus to display a plurality of results by combining the calculation results of the dose distribution calculation results for each of the plurality of irradiation directions of the irradiation unit when irradiating the object with the charged particle beam. It is possible to easily confirm the result of the addition of the calculation results of the dose distribution for each irradiation direction.

As mentioned above, although embodiment of this invention was described, this invention is not limited to said embodiment, A various change can be made. For example, the structure of each part in the above-described charged particle beam therapy system 1 can be appropriately changed.

In the above embodiment, the dose distribution calculation unit 105 of the charged particle beam therapy system 1 calculates the dose distribution when the charged particle beam is irradiated to the homogeneous medium corresponding to the irradiated object and the treatment plan information. The case has been described where the matching rate of the dose distribution in the homogeneous medium calculated as above is calculated, and the evaluation concerning the treatment plan information is performed based on the matching rate. However, the dose distribution calculating unit 105 may be configured to calculate only the dose distribution when the charged particle beam is irradiated to the homogeneous medium corresponding to the irradiation target.

Further, in the above embodiment, in the charged particle beam treatment apparatus 1, the treatment plan information is acquired, and the irradiation unit 103 performs the irradiation of the charged particle beam based on the treatment plan information under the control of the control unit 102. Then, the case has been described where the charged particle beam information acquisition unit 104 acquires the information related to the charged particle beam, and the dose distribution calculation unit 105 performs the calculation based on the information. However, the charged particle beam information acquiring unit 104 and the dose distribution calculating unit 105 may be an evaluation device independent of the charged particle beam therapy system 1. In this case, the functions (the charged particle beam information acquisition unit 104 and the dose distribution calculation unit 105) in the broken line shown in FIG. 3 become independent. Even in this case, the information on the charged particle beam to be irradiated based on the treatment plan information is acquired by the charged particle beam information acquisition unit 104, and the dose in the homogeneous medium when the homogeneous particle is irradiated with the charged particle beam The distribution is calculated by the dose distribution calculation unit 105. Therefore, as in the prior art, setting a homogeneous medium such as a water phantom and a dosimeter etc. for measurement of the dose distribution, as compared to the case where the dose distribution is measured by irradiating charged particle beams, etc. The work of can be omitted. Therefore, also in this evaluation device, it is possible to save the work relating to the evaluation of the dose distribution of the charged particle beam when the charged particle beam is irradiated based on the treatment plan.

In the evaluation device, if it is possible to acquire treatment plan information and information on charged particle beams in the charged particle beam treatment device based on the treatment plan information, calculation relating to dose distribution can be performed. Therefore, the evaluation device may not have a dosimeter or the like. However, the evaluation device may be configured to additionally include a communication unit (a communication unit having a function corresponding to the communication unit 101 in FIG. 3) for acquiring the treatment plan information.

DESCRIPTION OF SYMBOLS 1 ... Charged particle beam treatment apparatus, 2 ... irradiation part, 3 ... accelerator, 7 ... control part, 9 ... irradiation nozzle, 15 ... patient (irradiated body), 70 ... treatment plan apparatus, 101 ... communication part, 102 ... control 103, an irradiation unit, 104, a charged particle beam information acquisition unit, 105, a dose distribution calculation unit.

Claims

An irradiation unit which irradiates the charged particle beam emitted from the accelerator based on the treatment plan information determined by the treatment planning device;
A charged particle beam information acquisition unit that acquires information related to a charged particle beam irradiated from the irradiation unit;
A dose distribution calculation unit that calculates a dose distribution when the charged particle beam is irradiated to the irradiation target based on the information related to the charged particle beam acquired by the charged particle beam information acquisition unit;
A charged particle beam therapy apparatus comprising:
The dose distribution calculation unit is a matching rate between the calculation result of the dose distribution when the object is irradiated with the charged particle beam and the dose distribution of the object calculated based on the treatment plan information. The charged particle beam therapy system according to claim 1, wherein
The dose distribution calculation unit is a matching rate between the calculation result of the dose distribution when the object is irradiated with the charged particle beam and the dose distribution of the object calculated based on the treatment plan information. The charged particle beam therapy system according to claim 2, wherein the evaluation relating to the treatment plan information is performed on the basis of.
The charged particle beam therapy system according to any one of claims 1 to 3, wherein the charged particle beam information acquisition unit is provided in the irradiation unit.
The dose distribution calculating unit acquires a CT image related to the irradiated object acquired after the preparation of the treatment plan information, and the CT image and the charged particle beam acquired by the charged particle beam information acquiring unit 5. The charged particle beam therapy system according to any one of claims 1 to 4, wherein a dose distribution when the charged particle beam is irradiated to the irradiation object is calculated based on the information according to and.
The irradiation unit irradiates the charged particle beam emitted from the accelerator from a plurality of directions, and the dose distribution of the charged particle beam in the plane is uneven in one of the plurality of directions. ,
The charged particle beam information acquisition unit individually acquires information related to charged particle beams irradiated from a plurality of directions in the irradiation unit,
The dose distribution calculation unit irradiates the irradiation unit with the dose distribution when the charged particle beam is irradiated to the irradiation target based on the information related to the charged particle beam acquired by the charged particle beam information acquisition unit. The charged particle beam therapy system according to any one of claims 1 to 4, which is calculated for each direction.
The charged amount according to claim 6, wherein the dose distribution calculating unit calculates and displays the sum of calculation results of dose distributions for each of a plurality of irradiation directions of the irradiation unit when the charged particle beam is irradiated to the irradiation object. Particle therapy equipment.
A charged particle beam information acquisition unit that acquires information related to the charged particle beam when the charged particle beam is irradiated from the irradiation unit of the charged particle beam treatment apparatus based on the treatment plan information determined by the treatment planning apparatus;
A dose distribution calculation unit that calculates a dose distribution when the charged particle beam is irradiated to the irradiation target based on the information related to the charged particle beam acquired by the charged particle beam information acquisition unit;
An evaluation apparatus for a charged particle beam therapy apparatus, comprising: