WO2018169224A1 - Integrated environment management system customized for patient with allergic disease - Google Patents

Integrated environment management system customized for patient with allergic disease Download PDF

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Publication number
WO2018169224A1
WO2018169224A1 PCT/KR2018/002092 KR2018002092W WO2018169224A1 WO 2018169224 A1 WO2018169224 A1 WO 2018169224A1 KR 2018002092 W KR2018002092 W KR 2018002092W WO 2018169224 A1 WO2018169224 A1 WO 2018169224A1
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patient
information
environmental
environment
management system
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PCT/KR2018/002092
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French (fr)
Korean (ko)
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안강모
김지현
김영민
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사회복지법인 삼성생명공익재단
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Publication of WO2018169224A1 publication Critical patent/WO2018169224A1/en

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F15/00—Digital computers in general; Data processing equipment in general
    • G06F15/16—Combinations of two or more digital computers each having at least an arithmetic unit, a program unit and a register, e.g. for a simultaneous processing of several programs
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q50/00—Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
    • G06Q50/10—Services
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q50/00—Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
    • G06Q50/10—Services
    • G06Q50/26—Government or public services
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/70—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/80—Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication

Definitions

  • the present invention relates to a personalized integrated management system for patients with allergic diseases.
  • Allergic diseases e.g., atopic dermatitis, asthma, etc.
  • atopic dermatitis are chronic diseases that show clinical characteristics of 'allergic march', which gradually develops as a asthma and allergic rhinitis as atopic dermatitis develops in infants and young children. It is a disease that has a profound effect and causes a lot of social costs and therefore requires active treatment and management.
  • Allergic diseases such as atopic dermatitis and asthma are affected by indoor and outdoor environmental factors in addition to individual biological factors.
  • the recent deterioration of the living environment such as climate change, yellow dust, and the occurrence of fine dust, has a serious effect on the sick, and it is necessary to thoroughly manage the environment.
  • An object of the present invention is to construct a system that provides optimal environmental management and disease management guidelines to allergy sufferers by comprehensively analyzing the biological information of the patient, environmental information around the patient, patient behavior and disease characteristics information.
  • the ultimate goal of this system is to promote effective treatment and management of allergic diseases and further to minimize allergy marches.
  • an all-inclusive patient integrated environmental management system may be provided.
  • the user device for receiving the medical information of the allergic disease patient or providing behavior guidance information according to the environment of the patient, the information about the surrounding environment of the patient
  • the controller may be configured to operate another device connected to the system or to cause the user device to output behavior guide information.
  • the patient's medical information includes the patient's biological information and disease-related information
  • the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals.
  • the environmental information collection device includes an indoor environment information collecting unit and an outdoor environment information collecting unit, and the indoor environment information collecting unit includes indoor environment information in real time from at least one sensor module installed in a living space of a patient.
  • the outdoor environment information collecting unit may collect outdoor environment information in real time from at least one sensor module installed in an external measuring station adjacent to the living space of the patient.
  • a causal relationship between environmental harmful factors and allergic symptoms is analyzed for each patient by applying a statistical linear model, and the patient is customized to the patient based on the analysis result. Determine behavioral guidance information.
  • the causal relationship between environmental hazards and allergic symptoms is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
  • control unit may transmit the analysis result from the analysis device to an external device connected to the system through a communication device of the system, or may receive environmental management recommendation information from the external device.
  • an environmental management method using an integrated environmental management system customized for patients with allergic diseases may be provided.
  • the method may include receiving medical information of an allergic patient, collecting information about a patient's surroundings, and performing patient-specific behavior guide information based on the medical information and collected environmental information of the patient. And determining that the other device connected to the system is operated to improve the patient's surroundings according to the result of the determination, or action guide information may be provided to the patient.
  • a computer-readable recording medium having recorded thereon a program for executing the above method on a computer may be provided.
  • the system according to an embodiment of the present invention can be effectively used in health care institutions such as hospitals and clinics for the treatment and management of allergic diseases such as asthma and atopic dermatitis.
  • system configuration and operation principle can be applied to chronic disease management that is directly affected by indoor and outdoor environments as well as allergic diseases, and users can use the system by combining smart home networking function, environmental measurement sensor, and symptom monitoring function. Severity prediction and disease management at all times.
  • system can be used for other diseases other than allergic diseases.
  • the evidence-based treatment strategy can be adopted by preparing the ground air quality management basis for allergy sufferers, and further, the foundation of personalized precise treatment for allergy diseases is established. can do.
  • the disease management platform utilizing sensor-based environmental monitoring and control technology can be applied to other environmental diseases (e.g., respiratory diseases, cardiovascular diseases, multiple chemical sensitivity (MCS), etc.) in the future. Excellent expandability of the scope of application.
  • other environmental diseases e.g., respiratory diseases, cardiovascular diseases, multiple chemical sensitivity (MCS), etc.
  • Air quality management sensor applied to the living environment management platform of the system according to an embodiment of the present invention will be a mobile health technology for future disease management, It can be the foundation for building a healthy home for the health care of the general public as well as digital healthcare technology.
  • Figure 1 shows an all-inclusive disease patient customized environmental management system according to an embodiment of the present invention.
  • 2A to 2C are examples of an operation screen of a user device according to an embodiment of the present invention.
  • FIG. 3 is a flow chart illustrating an environmental management method using an integrated environmental management system customized for patients with allergic diseases according to an embodiment of the present invention.
  • an all-inclusive patient integrated environmental management system may be provided.
  • the user device for receiving the medical information of the allergic disease patient or providing behavior guidance information according to the environment of the patient, the information about the surrounding environment of the patient
  • the controller may be configured to operate another device connected to the system or to cause the user device to output behavior guide information.
  • the patient's medical information includes the patient's biological information and disease-related information
  • the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals.
  • the environmental information collection device includes an indoor environment information collecting unit and an outdoor environment information collecting unit, and the indoor environment information collecting unit includes indoor environment information in real time from at least one sensor module installed in a living space of a patient.
  • the outdoor environment information collecting unit may collect outdoor environment information in real time from at least one sensor module installed in an external measuring station adjacent to the living space of the patient.
  • a causal relationship between environmental harmful factors and allergic symptoms is analyzed for each patient by applying a statistical linear model, and the patient is customized to the patient based on the analysis result. Determine behavioral guidance information.
  • the causal relationship between environmental hazards and allergic symptoms is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
  • control unit may transmit the analysis result from the analysis device to an external device connected to the system through a communication device of the system, or may receive environmental management recommendation information from the external device.
  • an environmental management method using an integrated environmental management system customized for patients with allergic diseases may be provided.
  • the method may include receiving medical information of an allergic patient, collecting information about a patient's surroundings, and performing patient-specific behavior guide information based on the medical information and collected environmental information of the patient. And determining that the other device connected to the system is operated to improve the patient's surroundings according to the result of the determination, or action guide information may be provided to the patient.
  • a computer-readable recording medium having recorded thereon a program for executing the above method on a computer may be provided.
  • any part of the specification is to “include” any component, this means that it may further include other components, except to exclude other components unless otherwise stated.
  • the terms “... unit”, “module”, etc. described in the specification mean a unit for processing at least one function or operation, which may be implemented in hardware or software or a combination of hardware and software. .
  • a part of the specification is “connected” to another part, this includes not only “directly connected”, but also “connected with other elements in the middle”.
  • Figure 1 shows an all-inclusive disease patient customized environmental management system according to an embodiment of the present invention.
  • 2A to 2C are examples of an operation screen of a user device according to an embodiment of the present invention
  • FIG. 4 is an example of deriving an environmental solution using a unique algorithm according to an embodiment of the present invention.
  • the user device 100 for receiving medical information of the allergic patient or providing behavior guidance information according to the environment of the patient
  • the apparatus 200 includes an environment information collection apparatus 200 for collecting information about the surrounding environment and an analysis apparatus 300 for determining patient-specific behavior guide information based on medical information of the patient and collected environment information.
  • the control unit 100 may include a controller for operating another device 400 connected to the system or allowing the user device to output behavior guide information according to the analysis apparatus to improve the surrounding environment of the patient.
  • the patient's medical information includes the patient's biological information and disease-related information
  • the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals.
  • the predetermined time interval may be, for example, 1 hour, 3 hours, 6 hours, or the like, and may be differently predetermined according to the age, disease type, severity, etc. of the patient.
  • Biological information eg, gender, age, family history, etc.
  • disease information eg, severity, etc.
  • the user device 100 It can be provided to the medical institution through.
  • the user device 100 may be a PC, a smartphone, a tablet PC, a laptop, a mobile display device, or a smart phone capable of wireless or wired communication with an external device 400 such as a server or a medical device (eg, CT) provided in a medical institution.
  • an external device 400 such as a server or a medical device (eg, CT) provided in a medical institution.
  • a wearable device such as a watch may be included, but is not necessarily limited thereto.
  • the user device 100 may receive an image including medical data provided from the analysis apparatus 300 and display the same through a display unit provided in the user device 100, or may store and manage the received image by itself. Can be.
  • the user device 100 may transmit or receive various data to a server or the like provided to a medical institution in a remote place through a communication module or the like.
  • the server includes at least one of a picture archiving and communication system (PACS), an electronic medical record (EMR), a personal health record (PHR), a radial information system (RIS), or a cloud server connectable thereto. can do.
  • PPS picture archiving and communication system
  • EMR electronic medical record
  • PHR personal health record
  • RIS radial information system
  • cloud server connectable thereto.
  • a user may input his daily symptom score and time activity patterns at regular time intervals through the user device 100, and the input information may be a server such as a medical institution,
  • the analysis device 300 may be provided.
  • the constant time interval may be, for example, 1 hour, 3 hours, 6 hours, or the like, and may be previously determined differently according to the age, disease type, severity, etc. of the patient.
  • the environment information collection device 200 includes an indoor environment information collection unit 210 and an outdoor environment information collection unit 220, and the indoor environment information collection unit 210 is a living space of a patient.
  • the indoor environment information is collected in real time from the at least one sensor module installed in the outdoor environment, and the outdoor environment information collection unit 220 collects the outdoor environment information in real time from the at least one sensor module installed in an external measurement station adjacent to the living space of the patient. Can be collected.
  • At least one sensor may be pre-installed in a home where the patient lives, and the information collected through the sensor may be medically provided through a short range communication (eg, Bluetooth, etc.) or a remote communication using a base station. It may be provided to the server of the institution, the analysis device 300 and the like. The collection of information through the sensor may be performed in real time, and the measurement items may include fine dust concentration, VOCs, temperature, and humidity.
  • the outdoor environment information collection unit 220 may be pre-installed at an external measuring station adjacent to the patient's residence (eg, home).
  • the information collected through the outdoor environment information collection unit 220 may be provided in real time (eg, air pollution measurement network data) through a network of the public office (eg, the environment).
  • a user may input residence information through his user device 100.
  • the nearest external measuring station may be determined according to the input residential information, and information measured from the external measuring station may be provided to the user device 100 and the analysis apparatus 300. Items of the information collected through the outdoor environmental information collection unit 220 concentration concentration of fine dust (PM10, PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O 3 ), carbon monoxide (CO), etc. Can be.
  • a causal relationship between an environmental harmful factor and an allergic symptom is analyzed for each patient by applying a statistical linear model to the patient based on the analysis result.
  • Patient-specific behavioral guidance information can be determined.
  • the causal relationship between environmental hazards and allergic symptoms is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
  • the analysis apparatus 300 may be identified by analyzing the causal relationship between environmental harmful factors and allergic symptoms by applying a statistical model for each patient.
  • the exposure to environmental hazards is based on the user's actual evaluation of the indoor air quality based on the indoor monitoring results and the indoor air quality based on the indoor monitoring results using sensors.
  • Causality can be analyzed using exposure, or Time Weighted Average (TWA) concentration.
  • TWA Time Weighted Average
  • the analysis device 300 is unique to aggregate each input information (for example, the patient's personal information, location information, indoor and outdoor environmental monitoring information, clinical monitoring information, etc.) and provide patient-specific behavioral guidance based on this information. Algorithms can be used.
  • Algorithms for providing patient-specific behavioral guidelines can be changed by indoor / outdoor air pollutant items that can be measured by the sensor, but allergen-related items such as temperature, humidity, fine dust (PM 10 ), and nitrogen dioxide (NO 2 ) , ozone (O 3) a description of the algorithm using five items such as follows:
  • Risk factors (RF) to be used in the algorithm include indoor environment information (eg, temperature, humidity, CO 2 , fine dust, VOCs), outdoor environment information (eg, temperature, humidity, CO 2 , fine dust, NO 2 , O 3 , SO 2 , CO), time activity patterns (eg, user location information), and the like.
  • these risk factors are pre-collected together with basic information of the user (eg, related information such as height, weight, age, address, school, etc.) and symptom information (eg, sleep disorder, itching, redness, edema). 300 may be stored in advance.
  • OR and P-values can be calculated for each risk factor, and RFs that meet both OR and P-value conditions can be determined as the patient's unique risk factors. For example, risk determination is based on exposure assessment results of indoor and outdoor environmental risk factors and daily symptoms, and the odds ratio (OR) is greater than 1 and the P-value is less than 0.05. It is considered a risk factor. However, regarding the temperature and humidity, if the P-value is less than 0.05 regardless of the crossover ratio, it is considered a risk factor.
  • OR is a factor that indicates how much more dangerous the value of the risk factor is than when it is low. In other words, it may mean a relative increase in the risk ratio.
  • the P-value indicates the reliability of the result value of the OR, the lower the P-value value, the higher the reliability of the OR can be determined. In other words, if the OR is above a certain number (eg 1) and the P-value is low (eg below 95% of 0.05), the risk may be determined as the inherent risk of the subject patient. Risk factors that do not satisfy both the OR and P-value conditions are not considered in the patient.
  • the risk factor (RF) to be applied to the statistical model may be the basis of OR and P-value calculation as described above.
  • the statistical model applies a generalized linear model for data analysis, but may refer to the application of a statistical analysis model using a time weighted average (TWA) concentration for risks that can be measured indoors and outdoors simultaneously. .
  • TWA time weighted average
  • the risk code can be combined to determine the solution code.
  • the solution code is a code for providing a patient-specific behavior guide, and may be predefined and stored in the analysis device 300 or the like.
  • solution code 0101001 may be determined for the patient if the room temperature is greater than 26 degrees Celsius (° C) and thus provide patient-specific behavioral guidelines (eg, room cooling). have.
  • patient-specific behavioral guidelines eg, room cooling
  • Such behavioral guidance may be provided as a behavioral guidance in at least one of indoors and outdoors. In addition, it may be selectively provided according to the user's preference (eg, providing only indoor behavioral guidelines).
  • Alarms and behavioral guidelines can be delivered in accordance with the criteria given in Table 1 below for the exposure of each environmental hazard measured in real time.
  • Table 1 shows an example of alarm criteria for each environmental hazard. Criteria for alerting may vary depending on future environmental changes and individual analysis.
  • the behavioral guidance solution can be determined by integrating and analyzing the patient's biometric and daily collection information, and alerts and behavioral guidance can be provided to the patient in accordance with the determined solution. For example, if patient-specific sensitivity items are determined and the exposure environment requires an alert, a total of 1,408 action guidance solutions will occur, taking into account the five risk factors and each indoor / outdoor condition.
  • An example of such a solution decision algorithm is as follows.
  • Y i Patient i's symptoms of atopic dermatitis (0 or 1)
  • O3 i Ozone concentration of patient i
  • TCS topical corticosteroids
  • the solution code is determined according to each situation, and the environmental improvement action guide corresponding to the solution code is transmitted to each patient.
  • a single risk factor is shown in Table 2 below.
  • Table 2 shows an example of an environmental improvement solution (eg sensitive to a single risk) for each environmental exposure situation.
  • control unit transmits the analysis result from the analysis device to an external device connected to the system 1000 through a communication device (for example, a wired / wireless communication module of the system) of the system 1000 or
  • the device may receive environmental management recommendation information from an external device.
  • the external device may refer to an electronic device capable of communicating with the user device 100 or a server built in a medical institution as described above.
  • the electronic device may include various sensors, home appliances, PCs, smartphones, tablet PCs, laptops, or mobile display devices, wearable devices such as smart watches, and the like.
  • the electronic device described above is merely an example, and is not necessarily limited thereto.
  • the analysis result may not only be provided to the patient's personal device but also used as a basis for controlling an Internet of things (IoT) device existing in the patient's home.
  • IoT Internet of things
  • the patient's life pattern is analyzed based on the information collected for a predetermined period of time, and the recommended behavioral guide for each patient is determined according to the analyzed patient's life pattern and measured (monitored) environmental information. May be provided to the patient.
  • behavioral guidelines e.g. rest and restraint
  • the characteristics of the individual patient analyzed based on data collected for at least three months and measured in real time, both indoor and outdoor environmental and symptom information. And the like may be determined and provided to the patient.
  • Such recommended behavioral guidelines may be provided to patients whose at least one or more instructions are a user, as in FIG. 2B.
  • the recommended behavioral guide may be determined and provided differently for each patient, and may be provided in the form of a pop-up window on the screen of the user device 100 as shown in FIG. 2C.
  • the recommended action guideline may be provided in the form of a video including a sound such as an alarm, posture information to be taken by the patient, and first aid step information, not just a message such as text.
  • FIG. 3 is a flow chart illustrating an environmental management method using an integrated environmental management system customized for patients with allergic diseases according to an embodiment of the present invention.
  • Environmental management method using the integrated environmental management system for allergy disease patients step of receiving medical information of the allergic disease patient (S100), collecting information on the surrounding environment of the patient (S200) And determining patient-specific behavioral guidance information based on the medical information of the patient and the collected environmental information (S300), and another device connected to the system is operated to improve the patient's surroundings according to the result of the determination or , Behavioral guidance information may be provided to the patient (S400).
  • Computer-readable media includes both nonvolatile media, removable and non-removable media that can be accessed by a computer.
  • Computer readable media may include all computer storage media.
  • Computer storage media includes both non-volatile, removable and non-removable media implemented in any method or technology for storage of information such as computer readable instructions, data structures, program modules or other data.

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Abstract

As one embodiment of the present invention, an integrated environment management system customized for a patient with allergic disease is provided. The system according to the one embodiment of the present invention comprises: a user device for receiving medical information of a patient with allergic disease, or providing action guide information according to the patient's environment; an environment information collection device for collecting information on the patient's surrounding environment; and an analysis device for determining patient-specific action guide information on the basis of the medical information of the patient and the collected environment information, wherein the user device can comprise a control unit for operating another device connected with the system so as to improve the patient surrounding environment according to the result of the analysis device, or for enabling the user device to output the action guide information.

Description

알레르기 질환 환자 맞춤형 환경 통합관리 시스템Integrated environmental management system customized for allergy patients
본 발명은 알레르기 질환 환자 맞춤형 환경 통합관리 시스템에 관한 것이다. The present invention relates to a personalized integrated management system for patients with allergic diseases.
알레르기질환(예컨대, 아토피피부염, 천식 등)은 만성적 질환으로서 영유아기에 아토피피부염이 발생한 후 성장하면서 점차 천식 및 알레르기 비염으로 나타나는 '알레르기 행진'이라는 임상적 특징을 보이고 있어, 알레르기 질환자의 삶의 질에 심대한 영향을 끼치고 있고 많은 사회적 비용을 야기하며, 따라서 적극적인 치료 및 관리가 필요한 질환이다.Allergic diseases (e.g., atopic dermatitis, asthma, etc.) are chronic diseases that show clinical characteristics of 'allergic march', which gradually develops as a asthma and allergic rhinitis as atopic dermatitis develops in infants and young children. It is a disease that has a profound effect and causes a lot of social costs and therefore requires active treatment and management.
아토피피부염 및 천식 등의 알레르기 질환은 개인의 생물학적 요인 외에 실내외 환경적 요인의 영향을 많이 받는 질환이다. 특히 기후변화, 황사, 미세먼지 발생 증가 등 최근의 생활환경의 악화는 질환자를 중심으로 심각한 영향을 주고 있기 때문에 철저한 환경 관리가 필요하다.Allergic diseases such as atopic dermatitis and asthma are affected by indoor and outdoor environmental factors in addition to individual biological factors. In particular, the recent deterioration of the living environment, such as climate change, yellow dust, and the occurrence of fine dust, has a serious effect on the sick, and it is necessary to thoroughly manage the environment.
또한, 최근 실내 환경요인을 감지하는 센서와 사물 인터넷(IoT) 기술이 결합된 개인 맞춤형 환경 인자 모니터링 디바이스가 개발되고 있으나 지금까지의 장치는 건강한 일반인을 대상으로 제작되었고, 센서의 정밀성이 아직 기대에 미치지 못하며, 질환 맞춤형 관리를 위한 알고리즘이 없이 단순 측정 및 결과물의 디스플레이를 해주는 수준에 머물러 있다. 아직까지 알레르기 질환자에 최적화된 실내 환경 측정 및 관리 모니터링 시스템은 전무한 상태이다. In addition, the development of personalized environmental factor monitoring device that combines a sensor that detects indoor environmental factors and the Internet of Things (IoT) technology, but until now the device has been made for the healthy public, the precision of the sensor is still expected It does not reach the level and remains at the level of simple measurement and display of the result without the algorithm for disease-specific management. There are no indoor environmental measurement and management monitoring systems optimized for allergy sufferers.
신뢰할 만한 환경 유해인자 센서가 개발되어 사용된다 하더라도 환자 스스로 그 측정결과를 판단한다거나 환자 개인의 증상과 환경 인자와의 인과관계를 파악하고 환경을 제어하거나 질환을 관리하는 것은 매우 어렵다. 따라서 환자와 의료진의 양방향 소통이 가능한 환경-질환관리 시스템을 통해서 이러한 한계를 극복하고 알레르기질환 치료를 도모하는 것이 필요하나 아직까지 알레르기 질환 환자 맞춤형 환경 관리 시스템은 개발된 바가 없다.Even if a reliable environmental hazard sensor is developed and used, it is very difficult for the patient to judge the result of the measurement by himself or herself, understand the causal relationship between the individual's symptoms and environmental factors, control the environment or manage the disease. Therefore, it is necessary to overcome these limitations and promote the treatment of allergic diseases through an environment-disease management system capable of bi-directional communication between patients and medical staff. However, no customized environmental management system has been developed.
본 발명은 환자의 생물학적 정보, 환자 주변의 환경 정보, 환자의 행동 및 질환 특성 정보 등을 종합적으로 분석하여 알레르기 질환자에게 최적의 환경관리 및 질환관리 지침을 제공해주는 시스템을 구축하는 것을 목적으로 한다. 본 시스템을 통해 알레르기 질환의 효과적인 치료 및 관리를 도모하고 나아가 알레르기 행진을 최소화하는 것을 궁극적인 목적으로 한다.An object of the present invention is to construct a system that provides optimal environmental management and disease management guidelines to allergy sufferers by comprehensively analyzing the biological information of the patient, environmental information around the patient, patient behavior and disease characteristics information. The ultimate goal of this system is to promote effective treatment and management of allergic diseases and further to minimize allergy marches.
본 발명의 일 실시예로써, 알레르기 질환 환자 맞춤형 환경 통합관리 시스템이 제공될 수 있다. As an embodiment of the present invention, an all-inclusive patient integrated environmental management system may be provided.
본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템은, 알레르기 질환 환자의 의료정보를 입력 받거나 환자의 환경에 따른 행동 지침 정보를 제공하기 위한 사용자 디바이스, 환자의 주변 환경에 대한 정보를 수집하기 위한 환경정보 수집 장치 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하기 위한 분석 장치를 포함하고, 사용자 디바이스에는 분석 장치의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스를 동작시키거나, 사용자 디바이스로 하여금 행동 지침 정보를 출력하게 하는 제어부가 포함될 수 있다. Integrated environment management system tailored to allergy disease patients according to an embodiment of the present invention, the user device for receiving the medical information of the allergic disease patient or providing behavior guidance information according to the environment of the patient, the information about the surrounding environment of the patient A device for collecting environmental information for collection and an analysis device for determining patient-specific behavioral guidance information based on the medical information and collected environmental information of the patient, and the user device includes improving the surrounding environment of the patient according to the results of the analysis device. The controller may be configured to operate another device connected to the system or to cause the user device to output behavior guide information.
또한, 환자의 의료정보에는 환자의 생물학적 정보 및 질환 관련 정보가 포함되어 있고, 환자의 질환 관련 정보는 실시간 또는 소정의 시간 간격으로 환자로부터 사용자 디바이스를 통하여 입력됨으로써 수집될 수 있다.In addition, the patient's medical information includes the patient's biological information and disease-related information, the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals.
본 발명의 일 실시예에 따른 환경정보 수집 장치에는 실내 환경정보 수집부와 실외 환경정보 수집부가 포함되며, 실내 환경정보 수집부는 환자의 생활 공간에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실내의 환경 정보를 수집하고, 실외 환경정보 수집부는 환자의 생활 공간에 인접한 외부 측정소에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실외의 환경 정보를 수집할 수 있다. The environmental information collection device according to an embodiment of the present invention includes an indoor environment information collecting unit and an outdoor environment information collecting unit, and the indoor environment information collecting unit includes indoor environment information in real time from at least one sensor module installed in a living space of a patient. The outdoor environment information collecting unit may collect outdoor environment information in real time from at least one sensor module installed in an external measuring station adjacent to the living space of the patient.
본 발명의 일 실시예에 따른 분석 장치에서는 통계모델(generalized linear model)을 적용하여 환경 유해 인자와 알레르기 질환 증상 간의 인과관계를 각각의 환자 별로 분석하고, 분석의 결과에 기초하여 환자에 대한 환자 맞춤형 행동 지침 정보를 결정할 수 있다. In the analysis apparatus according to an embodiment of the present invention, a causal relationship between environmental harmful factors and allergic symptoms is analyzed for each patient by applying a statistical linear model, and the patient is customized to the patient based on the analysis result. Determine behavioral guidance information.
본 발명의 일 실시예에 따른 환경 유해 인자와 알레르기 질환 증상 간의 인과관계는 환자가 실내와 실외에 각각 머무른 시간, 실내 공기 질 측정의 결과, 실외 공기 질 측정의 결과에 기초하여 환자의 환경에 대한 실질적인 노출 정도로써 분석될 수 있다. The causal relationship between environmental hazards and allergic symptoms according to an embodiment of the present invention is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
또한, 본 발명의 일 실시예에 따른 제어부는 분석 장치로부터의 분석 결과를 시스템의 통신 장치를 통하여 시스템과 연결된 외부 장치로 송신하게 하거나, 외부 장치로부터 환경 관리 권장 정보를 수신할 수 있다. In addition, the control unit according to an embodiment of the present invention may transmit the analysis result from the analysis device to an external device connected to the system through a communication device of the system, or may receive environmental management recommendation information from the external device.
본 발명의 일 실시예로써, 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법이 제공될 수 있다. 본 발명의 일 실시예에 따른 방법은 알레르기 질환 환자의 의료정보를 입력받는 단계, 환자의 주변 환경에 대한 정보를 수집하는 단계 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하는 단계를 포함하고, 결정의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스가 동작되거나, 행동 지침 정보가 환자에게 제공될 수 있다. As an embodiment of the present invention, an environmental management method using an integrated environmental management system customized for patients with allergic diseases may be provided. According to an embodiment of the present invention, the method may include receiving medical information of an allergic patient, collecting information about a patient's surroundings, and performing patient-specific behavior guide information based on the medical information and collected environmental information of the patient. And determining that the other device connected to the system is operated to improve the patient's surroundings according to the result of the determination, or action guide information may be provided to the patient.
한편, 본 발명의 일 실시예로써, 전술한 방법을 컴퓨터에서 실행시키기 위한 프로그램을 기록한 컴퓨터로 읽을 수 있는 기록매체가 제공될 수 있다.Meanwhile, as an embodiment of the present invention, a computer-readable recording medium having recorded thereon a program for executing the above method on a computer may be provided.
본 발명의 일 실시예에 따른 시스템은 천식, 아토피피부염 등의 알레르기 질환의 치료와 관리를 위해 병원, 의원 등의 보건의료분야 기관 등에서 효과적으로 사용될 수 있다. The system according to an embodiment of the present invention can be effectively used in health care institutions such as hospitals and clinics for the treatment and management of allergic diseases such as asthma and atopic dermatitis.
또한, 시스템 구성 및 작동 원리는 알레르기 질환뿐만 아니라 실내외 환경의 직접적인 영향을 받는 만성 질환 관리에도 응용될 수 있고, 사용자는 스마트 홈 네트워킹 기능과 환경 측정 센서, 증상 모니터링 기능 등이 결합된 시스템을 통하여 질환의 중증도 예측 및 질병을 상시 관리할 수 있다. 또한, 본 시스템은 알레르기 질환 이외의 타 질환에도 활용될 수 있다. In addition, the system configuration and operation principle can be applied to chronic disease management that is directly affected by indoor and outdoor environments as well as allergic diseases, and users can use the system by combining smart home networking function, environmental measurement sensor, and symptom monitoring function. Severity prediction and disease management at all times. In addition, the system can be used for other diseases other than allergic diseases.
본 발명의 일 실시예에 따른 시스템을 이용한 분석 결과를 이용하여 알레르기 질환자의 실내 공기질 관리 근거를 마련함으로써 근거 중심의 치료 전략을 채택할 수 있게 되고 나아가 알레르기 질환에 대한 개인맞춤형 정밀 진료의 기반을 구축할 수 있다.By using the analysis result using the system according to an embodiment of the present invention, the evidence-based treatment strategy can be adopted by preparing the ground air quality management basis for allergy sufferers, and further, the foundation of personalized precise treatment for allergy diseases is established. can do.
또한, 센서 기반의 환경 모니터링 및 제어 기술을 활용한 질환 관리 플랫폼은 향후 여타의 환경성 질환(예컨대, 호흡기질환, 심혈관질환, 복합화학물질과민증(multiple chemical sensitivity, MCS) 등)에도 적용될 수 있으므로, 기술 적용 범위의 확장성이 우수하다.In addition, the disease management platform utilizing sensor-based environmental monitoring and control technology can be applied to other environmental diseases (e.g., respiratory diseases, cardiovascular diseases, multiple chemical sensitivity (MCS), etc.) in the future. Excellent expandability of the scope of application.
향후 유전형을 포함하는 환자별 민감도와 실내외 생활 환경에의 노출 평가로 상호 연관성 분석과 유전-환경 상호작용 연구도 가능해질 것이며, 현재 수준보다 진일보된 개인 맞춤형 예방 치료 전략 수립이 가능해질 수 있다. In the future, the assessment of patient-specific sensitivity including genotyping and exposure to indoor and outdoor living environments will enable correlation analysis and genetic-environment interaction studies, and will enable the development of personalized preventive care strategies that are more advanced than current levels.
본 발명의 일 실시예에 따른 시스템의 생활 환경 관리 플랫폼에 적용되는 공기질 관리 센서, IoT 기반의 자료 전송, 공기질 관리를 위한 알고리즘 및 solution 기술, 양방향 소통 기능 등은 향후 질환자 관리를 위한 모바일 헬스 기술, 디지털 헬스케어 기술뿐만 아니라 일반인의 건강 관리를 위한 healthy home 구축의 기반이 될 수 있다.Air quality management sensor applied to the living environment management platform of the system according to an embodiment of the present invention, IoT-based data transmission, algorithm and solution technology for air quality management, two-way communication function, and the like will be a mobile health technology for future disease management, It can be the foundation for building a healthy home for the health care of the general public as well as digital healthcare technology.
도 1은 본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 나타낸다. Figure 1 shows an all-inclusive disease patient customized environmental management system according to an embodiment of the present invention.
도 2a 내지 도 2c는 본 발명의 일 실시예에 따른 사용자 디바이스의 동작 화면의 일 예이다. 2A to 2C are examples of an operation screen of a user device according to an embodiment of the present invention.
도 3은 도 1은 본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법을 나타낸 순서도이다.3 is a flow chart illustrating an environmental management method using an integrated environmental management system customized for patients with allergic diseases according to an embodiment of the present invention.
도 4는 본 발명의 일 실시예에 따른 고유의 알고리즘을 이용한 환경 솔루션 도출의 일 예이다.4 is an example of deriving an environmental solution using a unique algorithm according to an embodiment of the present invention.
본 발명의 일 실시예로써, 알레르기 질환 환자 맞춤형 환경 통합관리 시스템이 제공될 수 있다. As an embodiment of the present invention, an all-inclusive patient integrated environmental management system may be provided.
본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템은, 알레르기 질환 환자의 의료정보를 입력 받거나 환자의 환경에 따른 행동 지침 정보를 제공하기 위한 사용자 디바이스, 환자의 주변 환경에 대한 정보를 수집하기 위한 환경정보 수집 장치 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하기 위한 분석 장치를 포함하고, 사용자 디바이스에는 분석 장치의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스를 동작시키거나, 사용자 디바이스로 하여금 행동 지침 정보를 출력하게 하는 제어부가 포함될 수 있다. Integrated environment management system tailored to allergy disease patients according to an embodiment of the present invention, the user device for receiving the medical information of the allergic disease patient or providing behavior guidance information according to the environment of the patient, the information about the surrounding environment of the patient A device for collecting environmental information for collection and an analysis device for determining patient-specific behavioral guidance information based on the medical information and collected environmental information of the patient, and the user device includes improving the surrounding environment of the patient according to the results of the analysis device. The controller may be configured to operate another device connected to the system or to cause the user device to output behavior guide information.
또한, 환자의 의료정보에는 환자의 생물학적 정보 및 질환 관련 정보가 포함되어 있고, 환자의 질환 관련 정보는 실시간 또는 소정의 시간 간격으로 환자로부터 사용자 디바이스를 통하여 입력됨으로써 수집될 수 있다.In addition, the patient's medical information includes the patient's biological information and disease-related information, the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals.
본 발명의 일 실시예에 따른 환경정보 수집 장치에는 실내 환경정보 수집부와 실외 환경정보 수집부가 포함되며, 실내 환경정보 수집부는 환자의 생활 공간에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실내의 환경 정보를 수집하고, 실외 환경정보 수집부는 환자의 생활 공간에 인접한 외부 측정소에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실외의 환경 정보를 수집할 수 있다. The environmental information collection device according to an embodiment of the present invention includes an indoor environment information collecting unit and an outdoor environment information collecting unit, and the indoor environment information collecting unit includes indoor environment information in real time from at least one sensor module installed in a living space of a patient. The outdoor environment information collecting unit may collect outdoor environment information in real time from at least one sensor module installed in an external measuring station adjacent to the living space of the patient.
본 발명의 일 실시예에 따른 분석 장치에서는 통계모델(generalized linear model)을 적용하여 환경 유해 인자와 알레르기 질환 증상 간의 인과관계를 각각의 환자 별로 분석하고, 분석의 결과에 기초하여 환자에 대한 환자 맞춤형 행동 지침 정보를 결정할 수 있다. In the analysis apparatus according to an embodiment of the present invention, a causal relationship between environmental harmful factors and allergic symptoms is analyzed for each patient by applying a statistical linear model, and the patient is customized to the patient based on the analysis result. Determine behavioral guidance information.
본 발명의 일 실시예에 따른 환경 유해 인자와 알레르기 질환 증상 간의 인과관계는 환자가 실내와 실외에 각각 머무른 시간, 실내 공기 질 측정의 결과, 실외 공기 질 측정의 결과에 기초하여 환자의 환경에 대한 실질적인 노출 정도로써 분석될 수 있다. The causal relationship between environmental hazards and allergic symptoms according to an embodiment of the present invention is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
또한, 본 발명의 일 실시예에 따른 제어부는 분석 장치로부터의 분석 결과를 시스템의 통신 장치를 통하여 시스템과 연결된 외부 장치로 송신하게 하거나, 외부 장치로부터 환경 관리 권장 정보를 수신할 수 있다. In addition, the control unit according to an embodiment of the present invention may transmit the analysis result from the analysis device to an external device connected to the system through a communication device of the system, or may receive environmental management recommendation information from the external device.
본 발명의 일 실시예로써, 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법이 제공될 수 있다. 본 발명의 일 실시예에 따른 방법은 알레르기 질환 환자의 의료정보를 입력받는 단계, 환자의 주변 환경에 대한 정보를 수집하는 단계 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하는 단계를 포함하고, 결정의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스가 동작되거나, 행동 지침 정보가 환자에게 제공될 수 있다. As an embodiment of the present invention, an environmental management method using an integrated environmental management system customized for patients with allergic diseases may be provided. According to an embodiment of the present invention, the method may include receiving medical information of an allergic patient, collecting information about a patient's surroundings, and performing patient-specific behavior guide information based on the medical information and collected environmental information of the patient. And determining that the other device connected to the system is operated to improve the patient's surroundings according to the result of the determination, or action guide information may be provided to the patient.
한편, 본 발명의 일 실시예로써, 전술한 방법을 컴퓨터에서 실행시키기 위한 프로그램을 기록한 컴퓨터로 읽을 수 있는 기록매체가 제공될 수 있다.Meanwhile, as an embodiment of the present invention, a computer-readable recording medium having recorded thereon a program for executing the above method on a computer may be provided.
아래에서는 첨부한 도면을 참조하여 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자가 용이하게 실시할 수 있도록 본 발명의 실시예를 상세히 설명한다. 그러나 본 발명은 여러 가지 상이한 형태로 구현될 수 있으며 여기에서 설명하는 실시예에 한정되지 않는다. 그리고 도면에서 본 발명을 명확하게 설명하기 위해서 설명과 관계없는 부분은 생략하였으며, 명세서 전체를 통하여 유사한 부분에 대해서는 유사한 도면 부호를 붙였다. DETAILED DESCRIPTION Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings so that those skilled in the art may easily implement the present invention. As those skilled in the art would realize, the described embodiments may be modified in various different ways, all without departing from the spirit or scope of the present invention. In the drawings, parts irrelevant to the description are omitted in order to clearly describe the present invention, and like reference numerals designate like parts throughout the specification.
본 명세서에서 사용되는 용어에 대해 간략히 설명하고, 본 발명에 대해 구체적으로 설명하기로 한다. Terms used herein will be briefly described and the present invention will be described in detail.
본 발명에서 사용되는 용어는 본 발명에서의 기능을 고려하면서 가능한 현재 널리 사용되는 일반적인 용어들을 선택하였으나, 이는 당 분야에 종사하는 기술자의 의도 또는 판례, 새로운 기술의 출현 등에 따라 달라질 수 있다. 또한, 특정한 경우는 출원인이 임의로 선정한 용어도 있으며, 이 경우 해당되는 발명의 설명 부분에서 상세히 그 의미를 기재할 것이다. 따라서 본 발명에서 사용되는 용어는 단순한 용어의 명칭이 아닌, 그 용어가 가지는 의미와 본 발명의 전반에 걸친 내용을 토대로 정의되어야 한다. The terms used in the present invention have been selected as widely used general terms as possible in consideration of the functions in the present invention, but this may vary according to the intention or precedent of the person skilled in the art, the emergence of new technologies and the like. In addition, in certain cases, there is also a term arbitrarily selected by the applicant, in which case the meaning will be described in detail in the description of the invention. Therefore, the terms used in the present invention should be defined based on the meanings of the terms and the contents throughout the present invention, rather than the names of the simple terms.
명세서 전체에서 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 포함할 수 있음을 의미한다. 또한, 명세서에 기재된 "...부", "모듈" 등의 용어는 적어도 하나의 기능이나 동작을 처리하는 단위를 의미하며, 이는 하드웨어 또는 소프트웨어로 구현되거나 하드웨어와 소프트웨어의 결합으로 구현될 수 있다. 또한, 명세서 전체에서 어떤 부분이 다른 부분과 "연결"되어 있다고 할 때, 이는 "직접적으로 연결"되어 있는 경우뿐 아니라, "그 중간에 다른 소자를 사이에 두고" 연결되어 있는 경우도 포함한다. When any part of the specification is to "include" any component, this means that it may further include other components, except to exclude other components unless otherwise stated. In addition, the terms "... unit", "module", etc. described in the specification mean a unit for processing at least one function or operation, which may be implemented in hardware or software or a combination of hardware and software. . In addition, when a part of the specification is "connected" to another part, this includes not only "directly connected", but also "connected with other elements in the middle".
이하 첨부된 도면을 참고하여 본 발명을 상세히 설명하기로 한다.Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.
도 1은 본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 나타낸다. 도 2a 내지 도 2c는 본 발명의 일 실시예에 따른 사용자 디바이스의 동작 화면의 일 예이고, 도 4는 본 발명의 일 실시예에 따른 고유의 알고리즘을 이용한 환경 솔루션 도출의 일 예이다.Figure 1 shows an all-inclusive disease patient customized environmental management system according to an embodiment of the present invention. 2A to 2C are examples of an operation screen of a user device according to an embodiment of the present invention, and FIG. 4 is an example of deriving an environmental solution using a unique algorithm according to an embodiment of the present invention.
본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템(1000)은, 알레르기 질환 환자의 의료정보를 입력받거나 환자의 환경에 따른 행동 지침 정보를 제공하기 위한 사용자 디바이스(100), 환자의 주변 환경에 대한 정보를 수집하기 위한 환경정보 수집 장치(200) 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하기 위한 분석 장치(300)를 포함하고, 사용자 디바이스(100)에는 분석 장치의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스(400)를 동작시키거나, 사용자 디바이스로 하여금 행동 지침 정보를 출력하게 하는 제어부가 포함될 수 있다. User integrated environment management system 1000 for allergic disease patients according to an embodiment of the present invention, the user device 100 for receiving medical information of the allergic patient or providing behavior guidance information according to the environment of the patient, The apparatus 200 includes an environment information collection apparatus 200 for collecting information about the surrounding environment and an analysis apparatus 300 for determining patient-specific behavior guide information based on medical information of the patient and collected environment information. The control unit 100 may include a controller for operating another device 400 connected to the system or allowing the user device to output behavior guide information according to the analysis apparatus to improve the surrounding environment of the patient.
또한, 환자의 의료정보에는 환자의 생물학적 정보 및 질환 관련 정보가 포함되어 있고, 환자의 질환 관련 정보는 실시간 또는 소정의 시간 간격으로 환자로부터 사용자 디바이스를 통하여 입력됨으로써 수집될 수 있다. 소정의 시간 간격이라 함은, 예를 들어, 1시간, 3시간, 6시간 등일 수도 있고, 환자의 연령, 질병 종류, 중증도 등에 따라 상이하게 미리 결정되어 있을 수 있다.In addition, the patient's medical information includes the patient's biological information and disease-related information, the patient's disease-related information may be collected by input through the user device from the patient in real time or at predetermined time intervals. The predetermined time interval may be, for example, 1 hour, 3 hours, 6 hours, or the like, and may be differently predetermined according to the age, disease type, severity, etc. of the patient.
알레르기 질환자가 병원 등의 의료기관에 등록하면서 이러한 의료기관으로 제공할 수 있는 기본적인 환자의 생물학적 정보(에컨대, 성별, 연령, 가족력 등), 질환 정보(예컨대, 중증도 등) 등은 사용자 디바이스(100)를 통하여 의료기관으로 제공될 수 있다. Biological information (eg, gender, age, family history, etc.), disease information (eg, severity, etc.) of basic patients that allergic patients can provide to such medical institutions while registering in a medical institution such as a hospital, etc. may refer to the user device 100. It can be provided to the medical institution through.
사용자 디바이스(100)는 의료기관 등에 마련된 서버, 의료장치(예컨대, CT 등) 등의 외부 기기(400)와 무선 또는 유선 통신이 가능한 PC, 스마트폰, 테블릿 PC, 랩탑, 또는 이동형 디스플레이 장치, 스마트 워치와 같은 웨어러블 디바이스 등을 포함할 수 있지만, 반드시 이에 제한되는 것은 아니다. 또한, 사용자 디바이스(100)는 분석 장치(300)로부터 제공되는 의료용 데이터 등이 포함된 이미지 등을 수신하여 사용자 디바이스(100)에 마련된 디스플레이부를 통하여 디스플레이하거나, 수신된 이미지를 자체적으로 저장하여 관리할 수 있다. 또한, 사용자 디바이스(100)는 통신 모듈 등을 통하여 원격지의 의료 기관 등에 마련된 서버 등으로 각종 데이터를 송신하거나 수신할 수 있다. 본 발명의 일 실시예에 따른 서버는 PACS(Picture Archiving and Communication System), EMR(Electronic Medical Record), PHR(Personal Health Record), RIS(Radiology Information System) 중 적어도 하나이거나 이와 연결 가능한 클라우드 서버를 포함할 수 있다.The user device 100 may be a PC, a smartphone, a tablet PC, a laptop, a mobile display device, or a smart phone capable of wireless or wired communication with an external device 400 such as a server or a medical device (eg, CT) provided in a medical institution. A wearable device such as a watch may be included, but is not necessarily limited thereto. In addition, the user device 100 may receive an image including medical data provided from the analysis apparatus 300 and display the same through a display unit provided in the user device 100, or may store and manage the received image by itself. Can be. In addition, the user device 100 may transmit or receive various data to a server or the like provided to a medical institution in a remote place through a communication module or the like. The server according to an embodiment of the present invention includes at least one of a picture archiving and communication system (PACS), an electronic medical record (EMR), a personal health record (PHR), a radial information system (RIS), or a cloud server connectable thereto. can do.
도 2a에서와 같이, 사용자는 사용자 디바이스(100)를 통하여 자신의 매일매일의 증상(daily symptom score)과 시간 활동 양상 등을 일정한 시간 간격으로 입력할 수 있고, 입력된 정보는 의료기관 등의 서버, 분석 장치(300) 등으로 제공될 수 있다. 일정한 시간 간격이라 함은, 예를 들어, 1시간, 3시간, 6시간 등일 수도 있고, 환자의 연령, 질병 종류, 중증도 등에 따라 상이하게 미리 결정되어 있을 수 있다. As shown in FIG. 2A, a user may input his daily symptom score and time activity patterns at regular time intervals through the user device 100, and the input information may be a server such as a medical institution, The analysis device 300 may be provided. The constant time interval may be, for example, 1 hour, 3 hours, 6 hours, or the like, and may be previously determined differently according to the age, disease type, severity, etc. of the patient.
본 발명의 일 실시예에 따른 환경정보 수집 장치(200)에는 실내 환경정보 수집부(210)와 실외 환경정보 수집부(220)가 포함되며, 실내 환경정보 수집부(210)는 환자의 생활 공간에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실내의 환경 정보를 수집하고, 실외 환경정보 수집부(220)는 환자의 생활 공간에 인접한 외부 측정소에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실외의 환경 정보를 수집할 수 있다. The environment information collection device 200 according to an embodiment of the present invention includes an indoor environment information collection unit 210 and an outdoor environment information collection unit 220, and the indoor environment information collection unit 210 is a living space of a patient. The indoor environment information is collected in real time from the at least one sensor module installed in the outdoor environment, and the outdoor environment information collection unit 220 collects the outdoor environment information in real time from the at least one sensor module installed in an external measurement station adjacent to the living space of the patient. Can be collected.
예를 들면, 환자가 생활하는 가정 집에 적어도 하나 이상의 센서가 미리 설치되어 있을 수 있고, 이러한 센서를 통하여 수집된 정보는 근거리 통신(예컨대, 블루투스 등), 기지국을 이용한 원격 통신 등의 방식으로 의료 기관의 서버, 분석 장치(300) 등으로 제공될 수 있다. 센서를 통한 정보의 수집은 실시간으로 이루어질 수 있고, 측정 항목으로는 미세먼지 농도, VOCs, 온도, 습도 등일 수 있다. For example, at least one sensor may be pre-installed in a home where the patient lives, and the information collected through the sensor may be medically provided through a short range communication (eg, Bluetooth, etc.) or a remote communication using a base station. It may be provided to the server of the institution, the analysis device 300 and the like. The collection of information through the sensor may be performed in real time, and the measurement items may include fine dust concentration, VOCs, temperature, and humidity.
본 발명의 일 실시예에 따른 실외 환경정보 수집부(220)는 환자의 거주지(예컨대, 가정 집 등)에 인접한 외부 측정소에 미리 설치되어 있을 수 있다. 또한, 실외 환경정보 수집부(220)를 통하여 수집된 정보는 관공서(예컨대, 환경부)의 네트워크를 통하여 실시간으로 제공(예컨대, 대기오염측정망 자료 등)될 수도 있다. 사용자는 자신의 사용자 디바이스(100)를 통하여 주거지 정보를 입력할 수 있다. 입력된 주거지 정보에 따라 가장 인접한 외부 측정소가 결정되고, 외부 측정소로부터 측정되는 정보가 사용자 디바이스(100), 분석 장치(300)로 제공될 수 있다. 실외 환경정보 수집부(220)를 통하여 수집되는 정보의 항목은 미세먼지(PM10, PM2.5), 이산화질소 (NO2), 이산화황(SO2), 오존(O3), 일산화탄소(CO) 등의 농도일 수 있다. The outdoor environment information collection unit 220 according to an embodiment of the present invention may be pre-installed at an external measuring station adjacent to the patient's residence (eg, home). In addition, the information collected through the outdoor environment information collection unit 220 may be provided in real time (eg, air pollution measurement network data) through a network of the public office (eg, the environment). A user may input residence information through his user device 100. The nearest external measuring station may be determined according to the input residential information, and information measured from the external measuring station may be provided to the user device 100 and the analysis apparatus 300. Items of the information collected through the outdoor environmental information collection unit 220 concentration concentration of fine dust (PM10, PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O 3 ), carbon monoxide (CO), etc. Can be.
본 발명의 일 실시예에 따른 분석 장치(300)에서는 통계모델(generalized linear model)을 적용하여 환경 유해 인자와 알레르기 질환 증상 간의 인과관계를 각각의 환자 별로 분석하고, 분석의 결과에 기초하여 환자에 대한 환자 맞춤형 행동 지침 정보를 결정할 수 있다. In the analysis device 300 according to an embodiment of the present invention, a causal relationship between an environmental harmful factor and an allergic symptom is analyzed for each patient by applying a statistical linear model to the patient based on the analysis result. Patient-specific behavioral guidance information can be determined.
본 발명의 일 실시예에 따른 환경 유해 인자와 알레르기 질환 증상 간의 인과관계는 환자가 실내와 실외에 각각 머무른 시간, 실내 공기 질 측정의 결과, 실외 공기 질 측정의 결과에 기초하여 환자의 환경에 대한 실질적인 노출 정도로써 분석될 수 있다. The causal relationship between environmental hazards and allergic symptoms according to an embodiment of the present invention is based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. It can be analyzed by the actual degree of exposure.
본 발명의 일 실시예에 따르면, 분석 장치(300)에서는 통계모델을 적용하여 환경 유해 인자와 알레르기 질환 증상 간의 인과관계를 환자 별로 분석함으로써 규명할 수 있다. 이 때 환경 유해 인자 노출은 환자가 실내와 실외에 각각 머문 시간과 센서 등을 이용한 실내의 모니터링 결과에 기초한 실내 공기질, 대기 오염 측정망 등을 통해 평가된 실외 공기질을 종합적으로 고려하여 평가한 사용자의 실질적인 노출, 즉 시간 가중평균(Time Weighted Average, TWA) 농도를 이용하여 인과 관계를 분석할 수 있다. 또한, 분석 장치(300)에서는 각각의 입력된 정보(예컨대, 환자의 개인 정보, 위치 정보, 실내외 환경 모니터링 정보, 임상 모니터링 정보 등)을 종합하고 이에 근거하여 환자 맞춤형 행동 지침을 제공하기 위한 고유의 알고리즘을 사용할 수 있다. According to an embodiment of the present invention, the analysis apparatus 300 may be identified by analyzing the causal relationship between environmental harmful factors and allergic symptoms by applying a statistical model for each patient. At this time, the exposure to environmental hazards is based on the user's actual evaluation of the indoor air quality based on the indoor monitoring results and the indoor air quality based on the indoor monitoring results using sensors. Causality can be analyzed using exposure, or Time Weighted Average (TWA) concentration. In addition, the analysis device 300 is unique to aggregate each input information (for example, the patient's personal information, location information, indoor and outdoor environmental monitoring information, clinical monitoring information, etc.) and provide patient-specific behavioral guidance based on this information. Algorithms can be used.
환자 맞춤형 행동 지침을 제공하기 위한 알고리즘은 센서를 통해 측정 가능한 실내/외 공기오염물질 항목 등에 의해 변경될 수 있으나 알레르기 질환 관련 관심 항목인 온도, 습도, 미세먼지(PM10), 이산화질소(NO2), 오존(O3) 등의 다섯 가지 항목을 이용한 알고리즘에 대한 설명은 다음과 같다.Algorithms for providing patient-specific behavioral guidelines can be changed by indoor / outdoor air pollutant items that can be measured by the sensor, but allergen-related items such as temperature, humidity, fine dust (PM 10 ), and nitrogen dioxide (NO 2 ) , ozone (O 3) a description of the algorithm using five items such as follows:
알고리즘에 사용될 위험요소(risk factor, RF)로는 실내환경정보(예컨대, 온도, 습도, CO2, 미세먼지, VOCs), 실외환경정보(예컨대, 온도, 습도, CO2, 미세먼지, NO2, O3, SO2, CO), 시간활동 양상(예컨대, 사용자의 위치 정보) 등이 포함될 수 있다. 또한, 이러한 위험요소는 사용자의 기본정보(예컨대, 키, 몸무게, 연령, 주소지, 학교 등의 관계기관 정보) 및 증상정보(예컨대, 수면장애, 가려움증, 발적, 부종)와 함께 사전 수집되어 분석 장치(300) 등에 미리 저장되어 있을 수 있다. Risk factors (RF) to be used in the algorithm include indoor environment information (eg, temperature, humidity, CO 2 , fine dust, VOCs), outdoor environment information (eg, temperature, humidity, CO 2 , fine dust, NO 2 , O 3 , SO 2 , CO), time activity patterns (eg, user location information), and the like. In addition, these risk factors are pre-collected together with basic information of the user (eg, related information such as height, weight, age, address, school, etc.) and symptom information (eg, sleep disorder, itching, redness, edema). 300 may be stored in advance.
위험요소별로 OR, P-value를 계산하고, OR과 P-value의 조건을 모두 만족하는 RF들을 해당 환자 고유의 위험요소로 결정할 수 있다. 예를 들면, 위험요소 결정은 실내외 환경 위험요소의 노출평가결과와 매일의 증상에 대한 연관성 분석결과 교차비(odds ratio, OR)가 1보다 크고, P-value 가 0.05 보다 작은 항목을 대상 환자 고유의 위험요소로 판단한다. 단, 온도와 습도에 대해서는 교차비에 상관없이 P-value 가 0.05 보다 작으면 위험요소로 판단한다. 여기서, OR은 위험요소의 수치가 높을때가 낮을 때보다 얼마나 더 위험한지 여부를 나타내는 인자이다. 즉, 위험비의 상대적인 증가량을 의미할 수 있다. 또한, P-value는 OR의 결과 값에 대한 신뢰도를 나타내는 것으로 P-value 값이 낮을수록 OR의 신뢰도가 높다고 판단될 수 있다. 다시 말해서, OR이 일정 수치(예컨대, 1) 이상이고, P-value가 낮은(예컨대, 0.05인 95% 이하) 경우, 해당 위험요소를 대상 환자의 고유 위험요소로 결정할 수 있다. OR과 P-value 조건을 동시에 만족하지 않는 위험요소는 해당 환자에 있어서 고려하지 않는다. OR and P-values can be calculated for each risk factor, and RFs that meet both OR and P-value conditions can be determined as the patient's unique risk factors. For example, risk determination is based on exposure assessment results of indoor and outdoor environmental risk factors and daily symptoms, and the odds ratio (OR) is greater than 1 and the P-value is less than 0.05. It is considered a risk factor. However, regarding the temperature and humidity, if the P-value is less than 0.05 regardless of the crossover ratio, it is considered a risk factor. Here, OR is a factor that indicates how much more dangerous the value of the risk factor is than when it is low. In other words, it may mean a relative increase in the risk ratio. In addition, the P-value indicates the reliability of the result value of the OR, the lower the P-value value, the higher the reliability of the OR can be determined. In other words, if the OR is above a certain number (eg 1) and the P-value is low (eg below 95% of 0.05), the risk may be determined as the inherent risk of the subject patient. Risk factors that do not satisfy both the OR and P-value conditions are not considered in the patient.
각 환자 별로 환경 위험요소에 대한 영향이 다르게 나타날 수 있으며, 위험요소 1개, 2개, 3개, 4개, 혹은 5개 등에 대하여 해당 환자가 반응할 수 있다. 통계 모델에 적용될 위험요소(RF)는 전술한 바와 같이 OR, P-value 산출의 기초가 될 수 있다. 통계 모델은 데이터 분석을 위한 일반화 선형 모형(generalized linear model)을 적용하되, 실내외 동시 측정이 가능한 위험요소에 대해서는 시간 가중평균(Time Weighted Average, TWA) 농도를 이용한 통계분석 모델 적용을 지칭할 수 있다. 산출된 OR 및 P-value에 기초하여 위험요소를 조합하여 솔루션 코드를 판별해낼 수 있다. 이러한 솔루션 코드는 환자 맞춤형 행동 지침을 제공하기 위한 코드로서, 미리 정의되어 분석 장치(300) 등에 저장되어 있을 수 있다. 예를 들면, 위험요소 1개에 민감할 경우, 실내의 온도가 26 도(℃) 이상인 경우 해당 환자에 대하여는 솔루션 코드 0101001이 결정되어 그에 따른 환자 맞춤형 행동 지침(ex. 실내 냉방)이 제공될 수 있다. 이러한 행동 지침은 실내 및 실외 중 적어도 한 곳에서의 행동지침으로써 제공될 수 있다. 또한 사용자의 선호도에 따라 선별적으로 제공(예컨대, 실내에서의 행동지침만 제공 등)될 수 있다. Each patient may have a different impact on environmental risks, and the patient may respond to one, two, three, four, or five risk factors. The risk factor (RF) to be applied to the statistical model may be the basis of OR and P-value calculation as described above. The statistical model applies a generalized linear model for data analysis, but may refer to the application of a statistical analysis model using a time weighted average (TWA) concentration for risks that can be measured indoors and outdoors simultaneously. . Based on the calculated OR and P-value, the risk code can be combined to determine the solution code. The solution code is a code for providing a patient-specific behavior guide, and may be predefined and stored in the analysis device 300 or the like. For example, if you are sensitive to one risk factor, solution code 0101001 may be determined for the patient if the room temperature is greater than 26 degrees Celsius (° C) and thus provide patient-specific behavioral guidelines (eg, room cooling). have. Such behavioral guidance may be provided as a behavioral guidance in at least one of indoors and outdoors. In addition, it may be selectively provided according to the user's preference (eg, providing only indoor behavioral guidelines).
실시간으로 측정되는 각 환경 위험요소의 노출 현황에 대하여 다음 표 1에서 제시하는 기준에 준하여 경보와 행동지침을 전달할 수 있다. 표 1은 환경 위험요소 별 경보 기준의 일 예를 나타낸다. 경보를 위한 준거치는 차후 환경변화 및 개인 별 분석 결과에 따라 달라질 수 있다. Alarms and behavioral guidelines can be delivered in accordance with the criteria given in Table 1 below for the exposure of each environmental hazard measured in real time. Table 1 shows an example of alarm criteria for each environmental hazard. Criteria for alerting may vary depending on future environmental changes and individual analysis.
Figure PCTKR2018002092-appb-I000001
Figure PCTKR2018002092-appb-I000001
환자의 고유 위험요소가 결정되면, 환자의 생체정보와 일일 수집정보와 통합되어 분석됨으로써 행동지침 솔루션이 결정되고, 결정된 솔루션에 따라 경보 및 행동지침이 환자에게 제공될 수 있다. 예를 들어, 환자별 민감 항목이 결정되고 노출 환경이 경보를 요하는 경우는 다섯 가지 위험요소 및 실내/외 각각의 조건을 고려할 경우, 총 1,408 개의 행동지침 솔루션이 발생한다. 이러한 솔루션 결정 알고리즘의 예시는 다음과 같다.Once the patient's unique risk factors are determined, the behavioral guidance solution can be determined by integrating and analyzing the patient's biometric and daily collection information, and alerts and behavioral guidance can be provided to the patient in accordance with the determined solution. For example, if patient-specific sensitivity items are determined and the exposure environment requires an alert, a total of 1,408 action guidance solutions will occur, taking into account the five risk factors and each indoor / outdoor condition. An example of such a solution decision algorithm is as follows.
<환자 맟춤형 민감한 위험요인 결정을 위한 통계분석 모델>:Statistical Model for Determining Patient Customized Sensitive Risk Factors:
Figure PCTKR2018002092-appb-I000002
Figure PCTKR2018002092-appb-I000002
Yi: 환자 i의 아토피피부염 증상 유무(0 또는 1)Y i : Patient i's symptoms of atopic dermatitis (0 or 1)
Tempi : 환자 i 의 노출 온도Temp i : Exposure temperature of patient i
RHi : 환자 i 의 노출 상대습도 RH i : Exposure relative humidity of patient i
PM10i: 환자 i 의 미세먼지 노출 농도PM10 i : fine dust exposure concentration of patient i
NO2i : 환자 i 의 이산화질소 노출농도NO2 i : Nitrogen dioxide exposure concentration in patient i
O3i : 환자 i 의 오존 노출농도O3 i : Ozone concentration of patient i
factor(fever): 발열유무(0 또는 1)factor (fever): Exothermic (0 or 1)
factor(TCS): 바르는 약(topical corticosteroid) 사용 여부(0 또는 1)factor (TCS): Whether topical corticosteroids are used (0 or 1)
Figure PCTKR2018002092-appb-I000003
: 각 위험요소에 대한 파라미터 값 (대상 환자의 신체 및 환경조건 등에 의하여 상이하게 결정될 수 있음)
Figure PCTKR2018002092-appb-I000003
: Parameter values for each risk factor (may be determined differently depending on the patient's physical and environmental conditions)
Figure PCTKR2018002092-appb-I000004
: 오차 항
Figure PCTKR2018002092-appb-I000004
Error term
각각의 상황에 따라 솔루션 코드가 정해지게 되며, 솔루션 코드에 해당하는 환경개선 행동지침이 각 환자에게 전달된다. 예를 들어, 그 중 단일 위험요소의 경우는 아래 표 2와 같다. 표 2는 각 환경 노출 상황에 따른 환경 개선 솔루션 예시(예컨대, 단일 위험요소에 민감한 경우)를 나타낸다.The solution code is determined according to each situation, and the environmental improvement action guide corresponding to the solution code is transmitted to each patient. For example, a single risk factor is shown in Table 2 below. Table 2 shows an example of an environmental improvement solution (eg sensitive to a single risk) for each environmental exposure situation.
Figure PCTKR2018002092-appb-I000005
Figure PCTKR2018002092-appb-I000005
또한, 본 발명의 일 실시예에 따른 제어부는 분석 장치로부터의 분석 결과를 시스템(1000)의 통신 장치(예컨대, 시스템의 유무선 통신 모듈 등)를 통하여 시스템(1000)과 연결된 외부 장치로 송신하게 하거나, 외부 장치로부터 환경 관리 권장 정보를 수신할 수 있다. 외부 장치는 전술한 바와 같이 의료 기관 등에 구축된 서버이거나 사용자 디바이스(100)와 통신 가능한 전자 디바이스를 지칭할 수 있다. 전자 디바이스에는 각종 센서, 가전기기, PC, 스마트폰, 테블릿 PC, 랩탑, 또는 이동형 디스플레이 장치, 스마트 워치와 같은 웨어러블 디바이스 등이 포함될 수 있다. 전술한 전자 디바이스는 예시일 뿐, 반드시 이에 제한되는 것은 아니다. 다시 말해서, 분석 결과는 환자의 개인 디바이스로 제공될 수 있을 뿐만 아니라, 환자의 집 등에 존재하는 사물인터넷(Internet of things, IoT) 디바이스를 제어하기 위한 기초로 활용될 수 있다. In addition, the control unit according to an embodiment of the present invention transmits the analysis result from the analysis device to an external device connected to the system 1000 through a communication device (for example, a wired / wireless communication module of the system) of the system 1000 or In addition, the device may receive environmental management recommendation information from an external device. The external device may refer to an electronic device capable of communicating with the user device 100 or a server built in a medical institution as described above. The electronic device may include various sensors, home appliances, PCs, smartphones, tablet PCs, laptops, or mobile display devices, wearable devices such as smart watches, and the like. The electronic device described above is merely an example, and is not necessarily limited thereto. In other words, the analysis result may not only be provided to the patient's personal device but also used as a basis for controlling an Internet of things (IoT) device existing in the patient's home.
본 발명의 일 실시예에 따르면 소정의 기간 동안 수집된 정보에 기초하여 환자의 생활 패턴이 분석되고, 분석된 환자의 생활 패턴 및 측정(모니터링)된 환경 정보에 따라 환자별 권장 행동 지침이 결정되어 환자에게 제공될 수 있다. 예를 들어, 최소 3개월 이상 모아진 데이터에 기반하여 분석된 환자 개인의 특성을 반영하고, 실시간으로 측정되는 실내외 환경 정보와 증상 정보에 기반하여 개별 환자를 위한 행동 지침(예컨대, 휴식, 외출의 제한 등)이 결정되어 환자에게 제공될 수 있다. According to an embodiment of the present invention, the patient's life pattern is analyzed based on the information collected for a predetermined period of time, and the recommended behavioral guide for each patient is determined according to the analyzed patient's life pattern and measured (monitored) environmental information. May be provided to the patient. For example, behavioral guidelines (e.g. rest and restraint) for individual patients are reflected in the characteristics of the individual patient analyzed based on data collected for at least three months and measured in real time, both indoor and outdoor environmental and symptom information. And the like may be determined and provided to the patient.
이러한 권장 행동 지침은 도 2b에서와 같이, 적어도 하나 이상의 지침이 사용자인 환자에게 제공될 수 있다. 권장 행동 지침은 환자별로 상이하게 결정되어 제공될 수 있고, 도 2c에서와 같이, 사용자 디바이스(100)의 화면 상에 팝업 창의 형태로 제공될 수도 있다. 또한, 권장 행동 지침은 단순히 텍스트 등의 메시지만 제공되는 것이 아닌 경보와 같은 사운드, 환자가 취해야 할 자세 정보, 응급 조치 단계 정보 등이 담긴 동영상의 형태로도 제공될 수 있다. Such recommended behavioral guidelines may be provided to patients whose at least one or more instructions are a user, as in FIG. 2B. The recommended behavioral guide may be determined and provided differently for each patient, and may be provided in the form of a pop-up window on the screen of the user device 100 as shown in FIG. 2C. In addition, the recommended action guideline may be provided in the form of a video including a sound such as an alarm, posture information to be taken by the patient, and first aid step information, not just a message such as text.
도 3은 도 1은 본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법을 나타낸 순서도이다.3 is a flow chart illustrating an environmental management method using an integrated environmental management system customized for patients with allergic diseases according to an embodiment of the present invention.
본 발명의 일 실시예에 따른 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법은 알레르기 질환 환자의 의료정보를 입력받는 단계(S100), 환자의 주변 환경에 대한 정보를 수집하는 단계(S200) 및 환자의 의료정보 및 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하는 단계(S300)를 포함하고, 결정의 결과에 따라 환자의 주변 환경을 개선시키기 위하여 시스템과 연결된 타 디바이스가 동작되거나, 행동 지침 정보가 환자에게 제공될 수 있다(S400). Environmental management method using the integrated environmental management system for allergy disease patients according to an embodiment of the present invention step of receiving medical information of the allergic disease patient (S100), collecting information on the surrounding environment of the patient (S200) And determining patient-specific behavioral guidance information based on the medical information of the patient and the collected environmental information (S300), and another device connected to the system is operated to improve the patient's surroundings according to the result of the determination or , Behavioral guidance information may be provided to the patient (S400).
본 발명의 일 실시예에 따른 방법과 관련하여서는 전술한 시스템에 대한 내용이 적용될 수 있다. 따라서, 방법과 관련하여, 전술한 시스템에 대한 내용과 동일한 내용에 대하여는 설명을 생략하였다.With regard to the method according to an embodiment of the present invention, the above description of the system may be applied. Therefore, with respect to the method, the same content as that for the above-described system has been omitted.
본 발명의 일 실시예는 컴퓨터에 의해 실행되는 프로그램 모듈과 같은 컴퓨터에 의해 실행가능한 명령어를 포함하는 기록 매체의 형태로도 구현될 수 있다. 컴퓨터 판독 가능 매체는 컴퓨터에 의해 액세스될 수 있는 비휘발성 매체, 분리형 및 비분리형 매체를 모두 포함한다. 또한, 컴퓨터 판독가능 매체는 컴퓨터 저장 매체를 모두 포함할 수 있다. 컴퓨터 저장 매체는 컴퓨터 판독가능 명령어, 데이터 구조, 프로그램 모듈 또는 기타 데이터와 같은 정보의 저장을 위한 임의의 방법 또는 기술로 구현된 비휘발성, 분리형 및 비분리형 매체를 모두 포함한다. One embodiment of the present invention can also be implemented in the form of a recording medium containing instructions executable by a computer, such as a program module executed by the computer. Computer-readable media includes both nonvolatile media, removable and non-removable media that can be accessed by a computer. In addition, computer readable media may include all computer storage media. Computer storage media includes both non-volatile, removable and non-removable media implemented in any method or technology for storage of information such as computer readable instructions, data structures, program modules or other data.
전술한 본 발명의 설명은 예시를 위한 것이며, 본 발명이 속하는 기술분야의 통상의 지식을 가진 자는 본 발명의 기술적 사상이나 필수적인 특징을 변경하지 않고서 다른 구체적인 형태로 쉽게 변형이 가능하다는 것을 이해할 수 있을 것이다. 그러므로 이상에서 기술한 실시예들은 모든 면에서 예시적인 것이며 한정적이 아닌 것으로 이해해야만 한다. 예를 들어, 단일형으로 설명되어 있는 각 구성 요소는 분산되어 실시될 수도 있으며, 마찬가지로 분산된 것으로 설명되어 있는 구성 요소들도 결합된 형태로 실시될 수 있다.The foregoing description of the present invention is intended for illustration, and it will be understood by those skilled in the art that the present invention may be easily modified in other specific forms without changing the technical spirit or essential features of the present invention. will be. Therefore, it should be understood that the embodiments described above are exemplary in all respects and not restrictive. For example, each component described as a single type may be implemented in a distributed manner, and similarly, components described as distributed may be implemented in a combined form.
본 발명의 범위는 상기 상세한 설명보다는 후술하는 특허청구범위에 의하여 나타내어지며, 특허청구범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.The scope of the present invention is shown by the following claims rather than the above description, and all changes or modifications derived from the meaning and scope of the claims and their equivalents should be construed as being included in the scope of the present invention. do.

Claims (8)

  1. 알레르기 질환 환자 맞춤형 환경 통합관리 시스템으로서, As an integrated environmental management system for allergy patients,
    알레르기 질환 환자의 의료정보를 입력받거나 상기 환자의 환경에 따른 행동 지침 정보를 제공하기 위한 사용자 디바이스; A user device for receiving medical information of an allergic patient or providing behavior guidance information according to the environment of the patient;
    상기 환자의 주변 환경에 대한 정보를 수집하기 위한 환경정보 수집 장치; 및An environmental information collection device for collecting information on the surrounding environment of the patient; And
    상기 환자의 의료정보 및 상기 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하기 위한 분석 장치를 포함하고, An analysis device for determining patient-specific behavior guide information based on the medical information of the patient and the collected environmental information;
    상기 사용자 디바이스에는 상기 분석 장치의 결과에 따라 상기 환자의 주변 환경을 개선시키기 위하여 상기 시스템과 연결된 타 디바이스를 동작시키거나, 상기 사용자 디바이스로 하여금 상기 행동 지침 정보를 출력하게 하는 제어부가 포함된 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The user device may include a controller configured to operate another device connected to the system or to cause the user device to output the behavior guide information according to a result of the analysis apparatus to improve the surrounding environment of the patient. Personalized integrated management system for patients with allergic diseases.
  2. 제 1 항에 있어서, The method of claim 1,
    상기 환자의 의료정보에는 상기 환자의 생물학적 정보 및 질환 관련 정보가 포함되어 있고, The medical information of the patient includes biological information and disease related information of the patient,
    상기 환자의 질환 관련 정보는 실시간 또는 소정의 시간 간격으로 상기 환자로부터 상기 사용자 디바이스를 통하여 입력됨으로써 수집 가능한 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The disease-related information of the patient can be collected by being input through the user device from the patient in real time or at predetermined time intervals, allergy disease patient customized environment integrated management system.
  3. 제 1 항에 있어서, The method of claim 1,
    상기 환경정보 수집 장치에는 실내 환경정보 수집부와 실외 환경정보 수집부가 포함되며, The environment information collection device includes an indoor environment information collection unit and an outdoor environment information collection unit,
    상기 실내 환경정보 수집부는 상기 환자의 생활 공간에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실내의 환경 정보를 수집하고, The indoor environment information collection unit collects the environment information of the room in real time from at least one sensor module installed in the living space of the patient,
    상기 실외 환경정보 수집부는 상기 환자의 생활 공간에 인접한 외부 측정소에 설치된 적어도 하나의 센서 모듈로부터 실시간으로 실외의 환경 정보를 수집하는 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The outdoor environmental information collection unit for allergy disease patients personalized environmental management system, characterized in that to collect the environmental information of the outdoor in real time from at least one sensor module installed in an external measuring station adjacent to the living space of the patient.
  4. 제 1 항에 있어서, The method of claim 1,
    상기 분석 장치에서는 통계모델(generalized linear model)을 적용하여 환경 유해 인자와 알레르기 질환 증상 간의 인과관계를 각각의 환자 별로 분석하고, 상기 분석의 결과에 기초하여 상기 환자에 대한 환자 맞춤형 행동 지침 정보를 결정하는 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The analysis apparatus applies a generalized linear model to analyze the causal relationship between environmental harmful factors and allergic disease symptoms for each patient, and determines patient-specific behavioral guide information for the patient based on the results of the analysis. Personalized integrated management system for patients with allergic diseases, characterized in that.
  5. 제 4 항에 있어서, The method of claim 4, wherein
    상기 환경 유해 인자와 알레르기 질환 증상 간의 인과관계는 상기 환자가 실내와 실외에 각각 머무른 시간, 실내 공기 질 측정의 결과, 실외 공기 질 측정의 결과에 기초하여 상기 환자의 환경에 대한 실질적인 노출 정도로써 분석되는 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The causal relationship between the environmental hazards and allergic symptoms is analyzed as the actual exposure of the patient to the environment based on the time the patient stays indoors and outdoors, the indoor air quality measurement, and the outdoor air quality measurement. Personalized integrated management system for patients with allergic diseases characterized in that it is.
  6. 제 1 항에 있어서, The method of claim 1,
    상기 제어부는 상기 분석 장치로부터의 분석 결과를 상기 시스템의 통신 장치를 통하여 상기 시스템과 연결된 외부 장치로 송신하게 하거나, 상기 외부 장치로부터 환경 관리 권장 정보를 수신하는 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템.The controller may be configured to transmit an analysis result from the analysis device to an external device connected to the system through a communication device of the system, or to receive environmental management recommendation information from the external device. Management system.
  7. 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법으로서, As an environmental management method using integrated environmental management system customized for allergy disease patients,
    알레르기 질환 환자의 의료정보를 입력받는 단계; Receiving medical information of an allergic patient;
    상기 환자의 주변 환경에 대한 정보를 수집하는 단계; 및Collecting information about the environment of the patient; And
    상기 환자의 의료정보 및 상기 수집된 환경정보에 기초하여 환자 맞춤형 행동 지침 정보를 결정하는 단계를 포함하고,Determining patient-specific behavior guide information based on the medical information of the patient and the collected environmental information;
    상기 결정의 결과에 따라 상기 환자의 주변 환경을 개선시키기 위하여 상기 시스템과 연결된 타 디바이스가 동작되거나, 상기 행동 지침 정보가 상기 환자에게 제공되는 것을 특징으로 하는 알레르기 질환 환자 맞춤형 환경 통합관리 시스템을 이용한 환경 관리 방법.According to the result of the determination, another device connected to the system is operated to improve the surrounding environment of the patient, or the behavior guide information is provided to the patient. How to manage.
  8. 제 7 항의 방법을 구현하기 위한 프로그램이 기록된 컴퓨터로 판독 가능한 기록 매체. A computer-readable recording medium having recorded thereon a program for implementing the method of claim 7.
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