WO2018152737A1 - Système de détection de dose et procédé de détection de dose - Google Patents

Système de détection de dose et procédé de détection de dose Download PDF

Info

Publication number
WO2018152737A1
WO2018152737A1 PCT/CN2017/074567 CN2017074567W WO2018152737A1 WO 2018152737 A1 WO2018152737 A1 WO 2018152737A1 CN 2017074567 W CN2017074567 W CN 2017074567W WO 2018152737 A1 WO2018152737 A1 WO 2018152737A1
Authority
WO
WIPO (PCT)
Prior art keywords
dose
audio input
detecting
voiceprint
injection
Prior art date
Application number
PCT/CN2017/074567
Other languages
English (en)
Chinese (zh)
Inventor
比丽尔•理查德•珍•玛丽
Original Assignee
创新精密仪器有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 创新精密仪器有限公司 filed Critical 创新精密仪器有限公司
Priority to PCT/CN2017/074567 priority Critical patent/WO2018152737A1/fr
Publication of WO2018152737A1 publication Critical patent/WO2018152737A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms

Definitions

  • the present invention belongs to the field of dose detection technology, and more particularly to a dose detection system and a dose detection method.
  • the injection pen has an injection dose adjustment knob and an injection unit.
  • the injection dose adjustment knob is used to adjust and set the injected dose.
  • the injection unit is used for injection according to the injection dose set by the injection dose adjustment knob.
  • the injection unit can include a piston for pushing the drug out of the needle for injection.
  • the present invention provides a dose detecting system for detecting an injection dose of a drug injection device, the drug injection device generating at least one click during setting and/or pushing out the injection dose.
  • the dose detection system includes:
  • a detecting device detachably connected to the drug injection device, configured to detect the click sound to obtain an audio input
  • an electronic device coupled to the detecting device via a wireless network, configured to receive the audio input; and [0009] a database coupled to the electronic device, configured to be populated by the drug injection device At least one first voiceprint produced during the injection of the dose;
  • the audio input and the first voiceprint are respectively composed of at least one click sound
  • the electronic device compares the audio input and the first voiceprint to determine the audio input.
  • the above-described dose detection system uses a detecting device to capture the click sound generated when the drug injection device is used, and The click sound is converted into an audio input, and the audio input is transmitted to the electronic device through the wireless network, and the electronic device compares the audio input with at least one first voiceprint stored in the database, if the click included in the audio input.
  • the number of sounds is equal to the number of clicks included in the first voiceprint, indicating that the actual dose of the drug injection device matches the predetermined injection dose, and the predetermined injection dose corresponding to the audio input is determined, and the audio input device is displayed.
  • the corresponding predetermined injection dose is displayed.
  • Another object of the present invention is to provide a dose detecting method for detecting an injection dose of a drug injection device, the drug injection device generating at least one click sound during setting and/or pushing out the injection dose.
  • the method of dose detection includes the following steps:
  • the above-described dose detecting method which first stores at least one first voiceprint generated during a predetermined injection dose by the drug injection device in a database, and then captures a click generated when the drug injection device is used. Sound, and convert the click sound into an audio input, and simultaneously transmit the audio input to the electronic device through the wireless network, and the electronic device compares the audio input with the first voiceprint, if the number of click sounds included in the audio input Equal to the number of clicks included in the first voiceprint, it means that the actual dose of the drug injection device is consistent with the predetermined injection dose, and the predetermined injection dose corresponding to the audio input can be determined, and the corresponding reservation of the audio input is displayed. Injection dose. In this way, the above-mentioned dose detection method can accurately detect the actual application dose of the patient, and the detection accuracy is high.
  • FIG. 1 is a schematic structural diagram of a dose detecting system according to an embodiment of the present invention.
  • FIG. 2 is a flowchart of a dose detecting method according to a first embodiment of the present invention
  • FIG. 3 is a flowchart of a dose detecting method according to a second embodiment of the present invention.
  • FIG. 4 is another flow chart of a dose detecting method according to a second embodiment of the present invention.
  • FIGS. 1 to 4 a preferred embodiment of the present invention is provided.
  • the dose detecting system 10 provided in this embodiment is mainly used for detecting the injected dose of the drug injection device 100 , and the drug injection device 100 is generated during setting and/or pushing the injected dose. At least one click sound, which is typically generated when the internal components of the drug injection device 100 are moved relative to each other.
  • the dose detecting system 10 includes:
  • the detecting device 102 is detachably connected to the drug injection device 100 for detecting a click sound to obtain an audio input 104;
  • the electronic device 106 is coupled to the detecting device 102 via the wireless network 108 for receiving the audio input 104;
  • the database 110 is coupled to the electronic device 106 and stores at least one first voiceprint generated during a predetermined injection dose by the drug injection device 100;
  • the audio input 104 and the first voiceprint are respectively composed of at least one click sound
  • the electronic device 106 compares the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104, and displays the audio input. 104 corresponding predetermined injection dose.
  • the drug injection device 100 Since the drug injection device 100 generates at least one click sound during setting and/or ejection of the injected dose,
  • the dose detecting system 10 uses the detecting device 102 to capture the click sound generated when the drug injecting device 100 is used, and converts the click sound into the audio input 104, and simultaneously, the audio is transmitted through the wireless network 108.
  • the input 104 is transmitted to the electronic device 106, and the electronic device 106 compares the audio input 104 with at least one first voiceprint stored in the database 110, if the number of clicks included in the audio input 104 is the same as the first voiceprint If the number of clicks included is equal, it means that the actual dose of the drug injection device 100 matches the predetermined injection dose, and the corresponding predetermined injection dose of the audio input 104 can be determined, and the corresponding predetermined injection dose of the audio input 104 can be displayed.
  • the dose detecting system 10 can accurately detect the actual dose of the patient, and the detection accuracy is high.
  • the second embodiment is substantially the same as the first embodiment, except that the database 110 further stores at least one generated during the reference injection dose set by the drug injection device 100.
  • the second voiceprint, the second voiceprint is composed of at least one click sound, and the electronic device 106 compares the audio input 104 and the second voiceprint to determine the corresponding reference injection dose of the audio input 104, and the predetermined injection dose and the reference injection dose. An alignment is made to determine if the predetermined injection dose is correct.
  • the dose detecting system 10 uses the detecting device 102 to capture the click sound generated when the drug injecting device 100 is used, and then compares one or more preset voiceprints to obtain the corresponding click.
  • the injected dose of sound can distinguish the two different sounds generated by the drug injection device 100, that is, the sound generated by the predetermined injection dose ⁇ and the sound generated by setting the reference injection dose ,, that is, by the drug injection device 100.
  • the first voiceprint generated during the predetermined injection dose and the second voiceprint generated during the reference injection dose set by the drug injection device 100 are pushed out, and then the audio input 104 is respectively input to the first voiceprint and the first by the electronic device 106.
  • the two voice patterns are compared to obtain a predetermined injection dose and a reference injection dose corresponding to the click sound, and if the number of click sounds included in the audio input 104 is equal to the number of click sounds included in the first voice print, The number of clicks included in the audio input 104 is equal to the number of clicks included in the second voiceprint, indicating that the actual dose of the drug injection device 100 matches the predetermined injection dose and the reference injection dose, that is, the predetermined injection.
  • the dose is the actual application dose.
  • the specific structure of the detecting device 102 in the first embodiment and the second embodiment may be:
  • the detecting device 102 includes: [0048] an acoustic sensor, the number of which is set to at least one, for converting an acoustic signal represented by the click sound into an electrical signal represented by the audio input 104;
  • the wireless communication module is coupled to the wireless network 108 for transmitting the audio input 104 to the electronic device 106.
  • the acoustic sensor may be a sound pressure sensor that converts the surface vibration of the acoustic emission wave into a voltage signal based on the piezoelectric effect of the crystal.
  • the specific structure of the electronic device 106 in the first embodiment and the second embodiment may be:
  • the electronic device 106 is any one of a server, a smart phone or a computer.
  • the electronic device 106 compares the at least one first voiceprint of the audio input 104 and the database 110 to determine the predetermined injection dose corresponding to the audio input 104.
  • the electronic device 106 can also compare the at least one second voiceprint of the audio input 104 and the database 110 to determine the corresponding reference injection dose of the audio input 104. Then, the electronic device 106 compares the corresponding predetermined injection dose and the reference injection dose of the audio input 104 to determine whether the corresponding predetermined injection dose is correct.
  • the electronic device 106 includes: a processing unit 112, configured to respectively obtain the number of click sounds included in each of the audio input 104, the first voiceprint, and the second voiceprint.
  • the number of clicks included in the first voiceprint corresponds to a predetermined injection dose
  • the number of click sounds included in the second voiceprint corresponds to a reference injection dose.
  • the wireless network 108 in the foregoing first embodiment and the second embodiment may be: the wireless network 108 includes any one of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network, and two Kind or more.
  • the embodiment further provides a dose detecting method for detecting an injection dose of the drug injection device 100, and the drug injection device 100 sets and/or pushes an injection dose. At least one click is generated during the period.
  • the dose detection method includes the following steps:
  • Step S101 storing at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100;
  • Step S102 detecting a click sound to obtain an audio input 104; [0058] wherein, the audio input 104 and the first voiceprint are respectively composed of at least one click sound.
  • the acoustic sensor is used to detect the click sound to obtain the audio input 104.
  • Step S103 Receive an audio input 104, compare the audio input 104 and the first voiceprint to determine the audio input.
  • the step of comparing the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104 is specifically: determining the number of click sounds included in the audio input 104 and the first voiceprint included Whether the number of click sounds is equal, if equal, the actual application dose of the output medicine injection device 100 is consistent with the predetermined injection dose, and the predetermined injection dose is the actual application dose. If not, the actual application dose is incorrect.
  • the electronic device 106 receives the audio input 104, compares the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104.
  • the method further includes: connecting the electronic device 106 to the electronic device 106 by using the wireless network 108, and transmitting the audio input 104 to the electronic device 106.
  • the step of receiving the audio input 104 is specifically: receiving the audio input 104 by way of the wireless network 108.
  • the wireless network 108 includes any one of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network, two or more
  • Step S104 Display a corresponding predetermined injection dose of the audio input 104;
  • the electronic device 106 displays the corresponding predetermined injection dose of the audio input 104.
  • the predetermined injection dose can be displayed by the electronic device 106 in text or a chart.
  • the above-described dose detecting method which first stores in the database 110 at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100, and then, when using the drug injection device 100
  • the generated click sound is converted into the audio input 104, and the audio input 104 is transmitted to the electronic device 106 via the wireless network 108, and the electronic device 106 compares the audio input 104 with the first voiceprint.
  • the number of clicks included in the audio input 104 is equal to the number of clicks included in the first voiceprint, indicating that the actual dose of the drug injection device 100 matches the predetermined injection dose, and the corresponding audio input 104 can be determined.
  • the injected dose is predetermined and the corresponding predetermined injection dose for the audio input 104 is displayed. In this way, the above-mentioned dose detection method can accurately detect the patient's reality.
  • the application dose is high, and the detection accuracy is high.
  • step S101 storing at least one generated during the ejection of the predetermined injection dose by the drug injection device 100
  • step S102 before detecting the click sound to obtain the audio input 104, further comprising the step S1011: storing at least one second sound generated during the setting of the reference injection dose by the drug injection device 100 a pattern, wherein the second voiceprint is composed of at least one click sound;
  • step S103 receiving the audio input 104, comparing the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104, and step S104: correspondingly presetting the audio input 104 Before the injection dose, the method further includes a step S1031: comparing the audio input 104 and the second voiceprint to determine a corresponding reference injection dose of the audio input 104, and comparing the predetermined injection dose with the reference injection dose to determine whether the predetermined injection dose is correct. .
  • the method further includes: separately obtaining the audio input 104, The number of click sounds included in each of the first voiceprint and the second voiceprint.
  • the step of comparing the predetermined injection dose and the reference injection dose to determine whether the predetermined injection dose is correct is specifically:
  • the dose detecting method which first stores in the database 110 at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100 and the reference injection dose period set by the drug injection device 100. At least one second voiceprint is generated, and then, the click sound generated when the drug injection device 100 is used is captured, and the click sound is converted into the audio input 104, and the audio input 104 is transmitted to the electronic device via the wireless network 108.
  • the device 106 compares the audio input 104 with the first voiceprint and the second voiceprint, respectively, if the number of clicks included in the audio input 104 is equal to the number of clicks included in the first voiceprint Similarly, the number of clicks included in the audio input 104 is equal to the number of clicks included in the second voiceprint, indicating the actual dose of the drug injection device 100 and the predetermined injection.
  • the dose and the reference injection dose are all consistent, that is, the predetermined injection dose is the actual application dose.
  • the actual hitting dose of the patient can be more accurately detected by the double comparison of the click sound generated by the drug injection device 100 with the first voiceprint and the second voiceprint respectively.
  • the detection accuracy is only the preferred embodiment of the present invention, and is not intended to limit the present invention. Any modifications, equivalent replacements, and improvements made within the spirit and principles of the present invention should be included in the present invention. Within the scope of protection of the present invention.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un système de détection de dose (10), comprenant : un dispositif de détection (102), un dispositif électronique (106) et une base de données (110). Le dispositif de détection (102) est utilisé pour recevoir un son de clic d'un dispositif d'injection de médicament et convertir le son de clic en une entrée de signal audio (104). Le dispositif électronique (106) compare l'entrée de signal audio (104) à une première empreinte vocale dans la base de données (110) pour déterminer un dosage d'injection préconfiguré correspondant à l'entrée de signal audio (104). Le système de détection de dose peut détecter avec précision une dose réelle administrée à un patient et présente une précision de détection élevée. La présente invention concerne un procédé de détection de dose, comprenant : étape S101 : stocker au moins une première empreinte vocale générée par un dispositif d'injection de médicament lors de l'injection d'un dosage d'injection préconfiguré ; étape S102 : détecter un son de clic pour acquérir une entrée de signal audio ; étape S103 : recevoir l'entrée de signal audio, et déterminer, par comparaison de l'entrée de signal audio à la première impression vocale, le dosage d'injection préconfiguré correspondant ; et étape S104 : indiquer la dose d'injection préconfigurée correspondant à l'entrée de signal audio.
PCT/CN2017/074567 2017-02-23 2017-02-23 Système de détection de dose et procédé de détection de dose WO2018152737A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/074567 WO2018152737A1 (fr) 2017-02-23 2017-02-23 Système de détection de dose et procédé de détection de dose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/074567 WO2018152737A1 (fr) 2017-02-23 2017-02-23 Système de détection de dose et procédé de détection de dose

Publications (1)

Publication Number Publication Date
WO2018152737A1 true WO2018152737A1 (fr) 2018-08-30

Family

ID=63253532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/074567 WO2018152737A1 (fr) 2017-02-23 2017-02-23 Système de détection de dose et procédé de détection de dose

Country Status (1)

Country Link
WO (1) WO2018152737A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482185B1 (en) * 1999-03-17 2002-11-19 B. Braun Melsungen Ag Injection device comprising a pen
US20040171983A1 (en) * 2003-02-24 2004-09-02 Integrated Sensing Systems, Inc. Fluid delivery system and sensing unit therefor
US20070017506A1 (en) * 2003-10-16 2007-01-25 Phillip Bell Dispensing apparatus
CN101405738A (zh) * 2006-03-20 2009-04-08 诺沃-诺迪斯克有限公司 用于机械式药物输送装置的电子模块
CN102065942A (zh) * 2008-06-20 2011-05-18 曼金德公司 用于对吸入工作进行实时描绘的交互式设备和方法
CN102905613A (zh) * 2010-03-22 2013-01-30 赛诺菲-安万特德国有限公司 用于确定与医疗装置相关的信息的装置和方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482185B1 (en) * 1999-03-17 2002-11-19 B. Braun Melsungen Ag Injection device comprising a pen
US20040171983A1 (en) * 2003-02-24 2004-09-02 Integrated Sensing Systems, Inc. Fluid delivery system and sensing unit therefor
US20070017506A1 (en) * 2003-10-16 2007-01-25 Phillip Bell Dispensing apparatus
CN101405738A (zh) * 2006-03-20 2009-04-08 诺沃-诺迪斯克有限公司 用于机械式药物输送装置的电子模块
CN102065942A (zh) * 2008-06-20 2011-05-18 曼金德公司 用于对吸入工作进行实时描绘的交互式设备和方法
CN102905613A (zh) * 2010-03-22 2013-01-30 赛诺菲-安万特德国有限公司 用于确定与医疗装置相关的信息的装置和方法

Similar Documents

Publication Publication Date Title
US11383027B2 (en) Integration of infusion pump with remote electronic device
US11935647B2 (en) System and method for medical surveillance through personal communication device
TWI664989B (zh) 藥物資訊偵測裝置及系統
US20170312457A1 (en) Mobile imaging modality for medical devices
CA2942470C (fr) Systeme de surveillance de maladie base sur internet (idms)
RU2459247C2 (ru) Электронный модуль для механического устройства введения лекарственных средств
US20190282446A1 (en) Computerized oral prescription administration with refillable medication dispensing devices and associated systems and methods
Madhushri et al. An mHealth tool suite for mobility assessment
JP2015018407A (ja) 治験支援装置、治験支援方法、治験支援プログラム及び携帯端末装置
WO2018152737A1 (fr) Système de détection de dose et procédé de détection de dose
US20160263316A1 (en) Methods and systems for communicating with an insulin administering device
CN105825038A (zh) 一种体征连续变化的获取方法、装置及系统
US20210268199A1 (en) Insulin-dosage detection device
JP7072568B2 (ja) 改良型薬剤送達デバイスのための方法及び装置
JP2023524017A (ja) 投与量捕捉可能なスマートシリンジおよびスマートフォン用のアプリ
US10232123B1 (en) Device and system for drug information detection
WO2023172264A1 (fr) Stylo-injecteur jetable à enregistrement intégré par communication nfc
US20140005498A1 (en) Medical application for mobile electronic device
US20230207079A1 (en) Smartphone-enabled systems, methods, devices, and computer program products for collecting performance data and using a selfie to generate self-verifying data sets
Slugocki et al. A Review of Emerging Technologies in Diabetes Management for Multiple-Dose Insulin-Injecting Patients With Type 2 Diabetes Who Self-monitor Blood Glucose
US20240108260A1 (en) System For Managing Treatment Of A Patient By Measuring Emotional Response
TWI509557B (zh) 醫療管理方法及電腦程式產品
JP2020057204A (ja) 投薬時間報知システム及び携帯端末装置
CN115458116A (zh) 一种基于物联网的远程药品核对方法和系统

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17897534

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17897534

Country of ref document: EP

Kind code of ref document: A1