WO2018124874A1 - Système de dosimétrie de rayonnement en temps réel - Google Patents

Système de dosimétrie de rayonnement en temps réel Download PDF

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Publication number
WO2018124874A1
WO2018124874A1 PCT/MY2017/050085 MY2017050085W WO2018124874A1 WO 2018124874 A1 WO2018124874 A1 WO 2018124874A1 MY 2017050085 W MY2017050085 W MY 2017050085W WO 2018124874 A1 WO2018124874 A1 WO 2018124874A1
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WO
WIPO (PCT)
Prior art keywords
radioluminescence
signal
dosimeter
radiation
dosimetry system
Prior art date
Application number
PCT/MY2017/050085
Other languages
English (en)
Inventor
Hairul Azhar ABDUL RASHID
A.K.M. Mizanur Rahman
MD. Zubair HASSAN TARIF
David Bradley
Original Assignee
Universiti Telekom Sdn. Bhd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiti Telekom Sdn. Bhd. filed Critical Universiti Telekom Sdn. Bhd.
Publication of WO2018124874A1 publication Critical patent/WO2018124874A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/02—Dosimeters
    • G01T1/10—Luminescent dosimeters

Definitions

  • the invention generally relates to a radiation dosimetry, and more particularly it relates to a real time radiation dosimetry based on radioluminescence.
  • thermoluminescent phosphors such as LiF (TLD- 100, TLD-600, TLD-700) and CaF 2 (TLD-300, TLD-400). These materials are contained in TLD badges and exposed to radiation prone locations for duration ranging from minutes to months. Thermoluminescent phosphors generate free electrons during exposure to irradiation, which are trapped in the forbidden band gap as soon as the irradiation stops. These electrons are captured in traps between the valence and conduction band of the material. When heat is applied to the thermoluminescent phosphors, the electrons recombine at recombination centers emitting light. This light is proportional to the cumulative absorbed radiation dose. An alternative method to release such traps is by using light of appropriate wavelength (material dependent) instead of heat. This process is known as Optically Stimulated Luminescence (OSL).
  • OSL Optically Stimulated Luminescence
  • the present invention provides a real time radiation dosimetry system that can accomplish instant read out measurement of the absorbed radiation dose based on radioluminescence.
  • the radioluminescence signal emitted by the radioluminescence dosimeter has constant intensity level for consistent dose rate. The intensity is linearly proportional to changes in the dose rate provided to the specimen, in order to calculate rate of the radiation absorption by the specimen in real time.
  • the radioluminescence dosimeter is a fabricated germanium-doped silica optical fiber.
  • the dosimetry system includes a radiation hardened fiber to guide the radioluminescence signal from the radioluminescence dosimeter to the radioluminescence reader.
  • the lens is a convex lens.
  • the radioluminescence dosimetry system includes a signal processor to analyze the radioluminescence signal received from the photodetector.
  • the radioluminescence dosimetry system is a real-time dosimetry system.
  • the radioluminescence dosimeter is reusable.
  • the radiation hardened fiber enables the radioluminescence signal with spatial resolution.
  • Fig. 1 shows the schematic of the real-time radioluminescence dosimeter system, according to the invention
  • Fig. 2 shows the profile of the radioluminescence dosimeter and the radiation hardened fiber, according to the invention
  • Fig. 3 shows the response of the radioluminescence dosimetry system in real time, according to the invention.
  • Fig. 4 shows the linearity of response and sensitivity of the radioluminescence dosimetry system, according to the invention.
  • a real time radioluminescence dosimetry system comprises a radioluminescence dosimeter (110), a radiation hardened fiber (120), a radioluminescence reader (represented by a dotted box) and an output unit (170).
  • the radioluminescence reader comprises of a cubic block in which a lens (140), a filter (150) are arranged and a photodetector (160) is attached to the cubic block on one side.
  • the radioluminescence dosimeter (110) is connected to the photodetector (160) via the radiation hardened fiber (120) and the cubic block.
  • the sensing material used for the radioluminescence dosimeter (110) is able to maintain constant level of intensity consistently at constant dose rate. Further, the intensity of radioluminescence signal is directly proportional to the changing dose rates.
  • the radioluminescence signal emitted by the radioluminescence dosimeter (110), has a correlation with the received radiation dose and the absorbed dose is displayed by the output unit (170).
  • the radioluminescence dosimetry system (100) is used to measure the dose rate (absorbed dose/time) of an ionizing radiation maintained with high spatial resolution (for point dose measurements) in real-time and is operable at different moisture, temperature and other conditions. Further, the radioluminescence system (100) is used to calculate the total absorbed dose from the real time data and display the current magnitude.
  • the radioluminescence dosimeter (110) is a fabricated germanium doped silica fiber, acts as a sensor is fitted into a probe and placed on or in vivo in a specimen.
  • the germanium doped silica fiber is aligned and attached to the radiation hardened fiber (120).
  • the fabrication of the germanium doped silica fiber (110) is by using Modified Chemical Vapor Deposition (MCVD) technique to ensure and tuned for the emission of the radioluminescence signal with sufficient germanium doping.
  • MCVD Modified Chemical Vapor Deposition
  • the radiation hardened fiber (120) acts as the waveguide to guide the radioluminescence signal from the radioluminescence dosimeter (110) to the photodetector (160) via the cubic block.
  • the cubic block is a light-tight housing which completely blocks any external light entering into it.
  • the radiation hardened fiber (120) is connected to the cubic block via a suitable connector (130) based on the diameter of the fiber (120).
  • the bandpass filter (150) filters the radioluminescence signal between two specific frequencies and eliminates noise and other spectra that are not necessary.
  • the lens (140) used is a convex lens converges the incoming filtered radioluminescence signal towards the photodetector (160).
  • the focal length of the lens (140) is selected according to the type of the photodetector (160) used and arrangement of the cubic block.
  • the photodetector (160) is a photomultiplier tube, CCD or avalanche photodiode, captures the filtered radioluminescence signals to detect the photons. These radioluminescence signals are transmitted to signal processing device and converted into electrical signal. Further, includes a processor, which process the electrical signal to provide readings of the absorbed radiation dose rate by the specimen and is displayed on the output unit (170).
  • the profile of the radioluminescence dosimeter probe or sensor (110) is a fabricated germanium doped silica fiber emits the radioluminescence signal upon exposure to the radiation.
  • the radioluminescence dosimeter (110) is placed inside a black polymer capsule forming the probe.
  • the diameter of the probe is chosen in accordance with the outer diameter of the radiation hardened fiber (120) so that the radioluminescence dosimeter (110) is aligned with the core of the radiation hardened fiber (120) and this enables to maintain spatial resolution of the radioluminescence signal.
  • a light proof jacket made from opaque black colored tape is used to cover the coupling portion between the radioluminescence dosimeter (110) and end portion of the radiation hardened fiber (120) to hold them tightly aligned to each other and block any external light entering into the coupling junction.
  • the radioluminescence dosimeter (110) is aligned with the core of the radiation hardened fiber (120) to ensure maximum radioluminescence signal transfer with spatial resolution.
  • the fabricated germanium doped silica fiber is reusable.
  • the response is consistent over the acquisition period of constant dose rate.
  • the radioluminescence dosimeter (110) emits the radioluminescence signal over prolonged period of time and the intensity of the radio luminescence signal increases proportionally with the increasing dose rate.
  • the intensity of the radioluminescence signal remains constant for a constant dose rates provided to the specimen.
  • the sensitivity of the radioluminescence dosimeter (110) changes linearly with the varying dose rates.
  • the radioluminescence dosimeter (110) emits radioluminescence signal with intensity which is linearly proportional to the radiation dose rates given to the specimen.
  • the present invention also provides a method to calculate absorbed radiation dose using the real time radioluminescence dosimetry system (100) comprises steps: attach at least one radioluminescence dosimeter (110) to the specimen (example: patient's body), expose the specimen to the radiation from the radiation source, emits radioluminescence signal by the radioluminescence dosimeter (110) upon the exposure to the radiation due to emission of photons which is caused by energy transition in valence and conduction energy bands, guide the emitted radioluminescence signal using the radiation hardened fiber (120) to the photodetector (160), where the radioluminescence signal are filtered using the bandpass filter (150) and focused towards the photodetector (160) using the lens (140), process the radioluminescence signal using processer, and display the rate of the radiation absorption by the specimen on the output unit (170).
  • the real time radioluminescence dosimetry system (100) finds its industrial applicability in radiotherapy in medical field and other related fields.
  • the radioluminescence dosimeter (110) is attached to the patient's body exposed to the radiation and emits the radioluminescence signal. Emission of photons during exposure to the ionizing radiation is caused by energy transition in valence and conduction energy bands.
  • the radioluminescence signals are acquired by the radioluminescence reader, processed by the processor and the real time response of the radioluminescence signal is displayed on the output unit (170).

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of Radiation (AREA)

Abstract

L'invention concerne un système de dosimétrie de radioluminescence (100) comprenant : un dosimètre de radioluminescence (110), fixé à un échantillon exposé à un rayonnement émis par une source de rayonnement, le dosimètre de radioluminescence (110) émettant un signal de radioluminescence lors de l'exposition au rayonnement ; un lecteur de radioluminescence comprenant en outre : une lentille (140), permettant de faire converger le signal de radioluminescence vers un photodétecteur (160) ; un filtre passe-bande (150), permettant d'éliminer le bruit du signal de radioluminescence ; et le photodétecteur (160), permettant de capturer le signal de radioluminescence filtré ; et une unité de sortie (170), permettant d'afficher une dose absorbée par un échantillon fixé au dosimètre de radioluminescence (110) en fonction du signal de radioluminescence obtenu en provenance du photodétecteur (170). Le signal de radioluminescence émis par le dosimètre de radioluminescence (110) présente un niveau d'intensité constant pour un même taux de dose et est linéairement proportionnel à des changements du taux de dose apportés à l'échantillon, de façon à calculer un taux de l'absorption de rayonnement par l'échantillon en temps réel.
PCT/MY2017/050085 2016-12-29 2017-12-27 Système de dosimétrie de rayonnement en temps réel WO2018124874A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MYPI2016704886A MY178849A (en) 2016-12-29 2016-12-29 Real time radiation dosimetry system
MYPI2016704886 2016-12-29

Publications (1)

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WO2018124874A1 true WO2018124874A1 (fr) 2018-07-05

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MY (1) MY178849A (fr)
WO (1) WO2018124874A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3653262A1 (fr) * 2018-11-16 2020-05-20 Sck Cen Détermination de dosimétrie par rayonnements
CN113260878A (zh) * 2018-12-21 2021-08-13 皇家学术促进会/麦吉尔大学 放射剂量计

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258264A (en) * 1978-07-12 1981-03-24 Fuji Photo Film Co., Ltd. Method of and apparatus for reading out a radiation image recorded in a stimulable phosphor
US20130248721A1 (en) * 2010-09-17 2013-09-26 Grand Victor McLelland Williams Radiation Dosimeter Detection System and Method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258264A (en) * 1978-07-12 1981-03-24 Fuji Photo Film Co., Ltd. Method of and apparatus for reading out a radiation image recorded in a stimulable phosphor
US20130248721A1 (en) * 2010-09-17 2013-09-26 Grand Victor McLelland Williams Radiation Dosimeter Detection System and Method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHIODINI, N. ET AL.: "Rare earth doped silica optical fibre sensors for dosimetry in medical and technical applications", ADVANCES IN OPTICS, vol. 2014, 14 October 2014 (2014-10-14), pages 1 - 9, XP055516958 *
RAHMAN, AKM MIZANUR ET AL.: "German ium-doped optical fiber for real-time radiation dosimetry", RADIATION PHYSICS AND CHEMISTRY, vol. 116, 2015, pages 170 - 175, XP029278400 *
RAHMAN, AKM MIZANUR ET AL.: "Real-time dosimetry in radiotherapy using tailored optical fibers", RADIATION PHYSICS AND CHEMISTRY, vol. 122, May 2016 (2016-05-01), pages 43 - 47, XP055516955 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3653262A1 (fr) * 2018-11-16 2020-05-20 Sck Cen Détermination de dosimétrie par rayonnements
US11300690B2 (en) 2018-11-16 2022-04-12 Sck-Cen Determination of radiation dosimetry
JP7471800B2 (ja) 2018-11-16 2024-04-22 エスセーカー・セーエーエヌ 放射線量測定の判定
CN113260878A (zh) * 2018-12-21 2021-08-13 皇家学术促进会/麦吉尔大学 放射剂量计

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