WO2018106153A3 - Препарат для лечения и/или профилактики инфекционно-воспалительных заболеваний - Google Patents

Препарат для лечения и/или профилактики инфекционно-воспалительных заболеваний Download PDF

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Publication number
WO2018106153A3
WO2018106153A3 PCT/RU2018/000163 RU2018000163W WO2018106153A3 WO 2018106153 A3 WO2018106153 A3 WO 2018106153A3 RU 2018000163 W RU2018000163 W RU 2018000163W WO 2018106153 A3 WO2018106153 A3 WO 2018106153A3
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WO
WIPO (PCT)
Prior art keywords
preparation
hydroxybenzoate
prophylaxis
treatment
infectious diseases
Prior art date
Application number
PCT/RU2018/000163
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English (en)
French (fr)
Other versions
WO2018106153A2 (ru
Inventor
Валентин Вячеславович ЛОВЦОВ
Original Assignee
Валентин Вячеславович ЛОВЦОВ
СВИРСКИЙ, Павел Михайлович
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Валентин Вячеславович ЛОВЦОВ, СВИРСКИЙ, Павел Михайлович filed Critical Валентин Вячеславович ЛОВЦОВ
Priority to ES18729014T priority Critical patent/ES2974996T3/es
Priority to RS20240241A priority patent/RS65250B1/sr
Priority to EP18729014.3A priority patent/EP3616687B8/en
Priority to PL18729014.3T priority patent/PL3616687T3/pl
Priority to HRP20240290TT priority patent/HRP20240290T1/hr
Publication of WO2018106153A2 publication Critical patent/WO2018106153A2/ru
Publication of WO2018106153A3 publication Critical patent/WO2018106153A3/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2101/00Chemical composition of materials used in disinfecting, sterilising or deodorising
    • A61L2101/32Organic compounds
    • A61L2101/46Macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10Apparatus features
    • A61L2202/15Biocide distribution means, e.g. nozzles, pumps, manifolds, fans, baffles, sprayers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к области медицины и химико-фармацевтической промышленности, а именно к антисептическим препаратам. Препарат в форме геля характеризующийся тем, что содержит следующие компоненты: хлоргексидина глюконат, метил-4-гидроксибензоат, этил-4-гидроксибензоат, пропил-4-гидроксибензоат, пропиленгликоль, гидроксиэтилцеллюлозу и воду. Препарат не обладает раздражающим действием и высоко эффективен в отношении патогенов, вызывающих заболевания, передающихся половым путем.
PCT/RU2018/000163 2017-04-27 2018-03-16 Препарат для лечения и/или профилактики инфекционно-воспалительных заболеваний WO2018106153A2 (ru)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES18729014T ES2974996T3 (es) 2017-04-27 2018-03-16 Preparación para el tratamiento y/o la profilaxis de enfermedades infecciosas inflamatorias
RS20240241A RS65250B1 (sr) 2017-04-27 2018-03-16 Priprema za lečenje i/ili profilaksu upalnih infektivnih bolesti
EP18729014.3A EP3616687B8 (en) 2017-04-27 2018-03-16 Preparation for the treatment and/or prophylaxis of inflammatory infectious diseases
PL18729014.3T PL3616687T3 (pl) 2017-04-27 2018-03-16 Preparat do leczenia i/lub profilaktyki zapalnych chorób zakaźnych
HRP20240290TT HRP20240290T1 (hr) 2017-04-27 2018-03-16 Priprema za liječenje i/ili profilaksu upalnih infektivnih bolesti

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2017114945A RU2639129C1 (ru) 2017-04-27 2017-04-27 Препарат для лечения и/или профилактики инфекционно-воспалительных заболеваний
RU2017114945 2017-04-27

Publications (2)

Publication Number Publication Date
WO2018106153A2 WO2018106153A2 (ru) 2018-06-14
WO2018106153A3 true WO2018106153A3 (ru) 2018-08-09

Family

ID=60718871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2018/000163 WO2018106153A2 (ru) 2017-04-27 2018-03-16 Препарат для лечения и/или профилактики инфекционно-воспалительных заболеваний

Country Status (8)

Country Link
EP (1) EP3616687B8 (ru)
ES (1) ES2974996T3 (ru)
HR (1) HRP20240290T1 (ru)
HU (1) HUE065317T2 (ru)
PL (1) PL3616687T3 (ru)
RS (1) RS65250B1 (ru)
RU (1) RU2639129C1 (ru)
WO (1) WO2018106153A2 (ru)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8104627A (nl) * 1980-10-23 1982-05-17 Mallinckrodt Inc Antimicrobieel middel, werkwijze voor het bereiden daarvan, en methode voor het bestrijden van micro-organismen met voornoemd middel.
IL100881A (en) * 1992-02-06 1996-06-18 Porat Michael Causal drug prevents diseases, devices and methods of using it
US20050181057A1 (en) * 2004-02-13 2005-08-18 Rosenberg Paul K. Vaginal lubricant
US20090185995A1 (en) * 2008-01-18 2009-07-23 Stacy Vochecowicz Lubricious, non-tacky personal lubricant
CN101332317A (zh) * 2008-07-24 2008-12-31 武汉杰士邦卫生用品有限公司 一种水溶性人体润滑剂

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANDERSEN A.: "Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products", INTERNATIONAL JOURNAL OF TOXICOLOGY, vol. 27, no. 4, 2008, pages 1 - 82, XP009517604, DOI: 10.1080/10915810802548359 *
ANONYMOUS: "Zaregistrirovan v gosudarstvennom reestre lekarstvennykh sredstv, registratsionn y nomer: P N015801/01", 8 November 2009 (2009-11-08), XP055649572, Retrieved from the Internet <URL:http://grLs.rosminzdrav.ru/GrLs_View_v2.aspx?routingGuid=1ceba65f-c113-4be5-80ca-374887487038&t=> [retrieved on 20180706] *
ANONYMOUS: "Zaregistrirovan v gosudarstvennom reestre lekarstvennykh sredstv, registratsionny nomer: P N012477/01", 18 July 2008 (2008-07-18), XP055649593, Retrieved from the Internet <URL:http://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=02fed3fc-45a9-45db-ba67-3bd1d63c8ea3&t=> [retrieved on 20180607] *

Also Published As

Publication number Publication date
WO2018106153A2 (ru) 2018-06-14
RS65250B1 (sr) 2024-03-29
RU2639129C1 (ru) 2017-12-19
EP3616687A2 (en) 2020-03-04
HUE065317T2 (hu) 2024-05-28
PL3616687T3 (pl) 2024-04-22
ES2974996T3 (es) 2024-07-02
HRP20240290T1 (hr) 2024-06-07
EP3616687A4 (en) 2020-12-30
EP3616687C0 (en) 2023-11-29
EP3616687B8 (en) 2024-01-17
EP3616687B1 (en) 2023-11-29

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