WO2018085954A1 - Peptides à activité antimicrobienne - Google Patents

Peptides à activité antimicrobienne Download PDF

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Publication number
WO2018085954A1
WO2018085954A1 PCT/CL2017/050063 CL2017050063W WO2018085954A1 WO 2018085954 A1 WO2018085954 A1 WO 2018085954A1 CL 2017050063 W CL2017050063 W CL 2017050063W WO 2018085954 A1 WO2018085954 A1 WO 2018085954A1
Authority
WO
WIPO (PCT)
Prior art keywords
peptide
peptides
venom
fraction
atcc
Prior art date
Application number
PCT/CL2017/050063
Other languages
English (en)
Spanish (es)
Inventor
Jorge ARAYA ROJAS
Hernan SEGUA FRANCO
Marco RAMIREZ GALLARDO
Jorge GONZALEZ CORTES
Alejandro CATALAN RODRIGUEZ
Iván NEIRA CORTES
Patricio ORREGO LILLO
Kely ORDENES GONZALEZ
Daniel MIERES CASTRO
William CORTES ARAYA
Camilo URBINA ALONSO
Original Assignee
Universidad De Antofagasta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad De Antofagasta filed Critical Universidad De Antofagasta
Publication of WO2018085954A1 publication Critical patent/WO2018085954A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

  • the invention described herein has its main field of application in the development of products for inhibiting and destroying bacteria, with special applicability to the treatment of infectious and contagious diseases caused by bacteria, in particular in the treatment of those bacteria that do not respond to antibiotic treatment or that They have developed resistance to existing antibiotics.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention a son champ d'application principal dans le développement de produits pour inhiber et détruire des bactéries, avec une application spéciale dans le traitement de maladies infectieuses causées par des bactéries, notamment dans le traitement de ces bactéries qui ne répondent pas au traitement avec des antibiotiques ou qui ont développé une résistance aux antibiotiques existants.
PCT/CL2017/050063 2016-11-14 2017-11-14 Peptides à activité antimicrobienne WO2018085954A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2016002890A CL2016002890A1 (es) 2016-11-14 2016-11-14 Peptidos con actividad antimicrobiana
CL2890-2016 2016-11-14

Publications (1)

Publication Number Publication Date
WO2018085954A1 true WO2018085954A1 (fr) 2018-05-17

Family

ID=59858437

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CL2017/050063 WO2018085954A1 (fr) 2016-11-14 2017-11-14 Peptides à activité antimicrobienne

Country Status (2)

Country Link
CL (1) CL2016002890A1 (fr)
WO (1) WO2018085954A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1161951A1 (fr) * 2000-04-11 2001-12-12 Xiamen Bioway Biotech Co., Ltd. Toxine de Selenocosmia huwena et son utilisation comme analgésique
MX2012003078A (es) * 2009-09-15 2012-08-03 Alomone Preclinical Ltd Nuevos peptidos aislados de veneno de araña y sus usos.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1161951A1 (fr) * 2000-04-11 2001-12-12 Xiamen Bioway Biotech Co., Ltd. Toxine de Selenocosmia huwena et son utilisation comme analgésique
MX2012003078A (es) * 2009-09-15 2012-08-03 Alomone Preclinical Ltd Nuevos peptidos aislados de veneno de araña y sus usos.

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
"ArachnoServer, Spider Toxin Database", BIOINFORMATICS/EMBL, 2010, Australia, Retrieved from the Internet <URL:http://www.arachnoserver.org/advancedsearch.html> [retrieved on 20180126] *
ABREU, T. F. ET AL.: "Peptidomics of Acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity", JOURNAL OF PROTEOMICS, vol. 151, 2017, pages 232 - 242, XP029850244 *
GARCIA F. ET AL.: "Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics. 2013", THE JOURNAL OF ANTIBIOTICS, vol. 66, no. 1, 2013, pages 3 - 10, XP055503459 *
HARRISON P. L. ET AL.: "Antimicrobial peptides from scorpion venoms", TOXICON, vol. 88, 2014, pages 115 - 137, XP055503242 *
KUHN-NENTWIG, L: "Antimicrobial and cytolytic peptides of venomous arthropods", CELL . MOL. LIFE SCI., vol. 60, 2003, pages 2651 - 2668, XP055503458 *
ORDENES, K. ET AL.: "Bioactive antimicrobial peptides present in Aphonopelma aberrans, tarantula endemic of Chile", EMBL SYMPOSIA, 2015, Retrieved from the Internet <URL:https://www.embo-embl-symposia.org/symposia/2015/EES15-07/posters_list.pdf> [retrieved on 20180126] *
WANG, K. ET AL.: "Research on peptide toxins with antimicrobial activities", ANN PHARMACOL PHARM, vol. 1, no. 2, 2016, pages 1006, XP055503516, Retrieved from the Internet <URL:https://pdfs.semanticscholar.org/9aa4/5feb8eab054878622ec4532683667110d2d2.pdf> [retrieved on 20180126] *

Also Published As

Publication number Publication date
CL2016002890A1 (es) 2017-06-30

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