WO2018078144A1 - Implant intraoculaire - Google Patents

Implant intraoculaire Download PDF

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Publication number
WO2018078144A1
WO2018078144A1 PCT/EP2017/077697 EP2017077697W WO2018078144A1 WO 2018078144 A1 WO2018078144 A1 WO 2018078144A1 EP 2017077697 W EP2017077697 W EP 2017077697W WO 2018078144 A1 WO2018078144 A1 WO 2018078144A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant
deflection
eye
optical axis
plane
Prior art date
Application number
PCT/EP2017/077697
Other languages
German (de)
English (en)
Inventor
Max Ostermeier
Stefan Meyer
Burkhard Dick
Original Assignee
Implandata Ophthalmic Products Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Implandata Ophthalmic Products Gmbh filed Critical Implandata Ophthalmic Products Gmbh
Priority to JP2019522811A priority Critical patent/JP7104694B2/ja
Priority to AU2017348634A priority patent/AU2017348634A1/en
Priority to CA3039583A priority patent/CA3039583A1/fr
Priority to EP17791677.2A priority patent/EP3547900A1/fr
Publication of WO2018078144A1 publication Critical patent/WO2018078144A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1683—Intraocular lenses having supporting structure for lens, e.g. haptics having filiform haptics

Definitions

  • the present invention relates to an implant for implantation in and / or on an eye with fixation means.
  • Implants of the type mentioned are known from the prior art, for example, as disc rings, which are fixed by means of fixing means, namely plate-shaped tabs, mostly in the sulcus ciliaris of the eye after implantation.
  • the implants are often equipped with a sensor for measuring intraocular pressure and a telemetry unit for transmitting the measured signal detected by the sensor, that is, for example, an induction coil arranged in the plane of the disc ring.
  • Such implants are indeed fixed in the implanted state with respect to the optical axis of the eye, so defined by the axis of rotational symmetry of the eye pupil axis in that the tabs protrude into the sulcus ciliaris.
  • the eye must be at a disadvantage before the
  • Implanting one of the known implants can be measured consuming, so that a suitable implant for fixation can be selected based on the size of the implant concerned disc ring diameter.
  • the known implants ensure virtually no adaptation to the naturally occurring variation of anatomical conditions, for example the diameter spectrum defined by the sulcus ciliaris in patients. Specifically, there is a risk in the known implants that they are poorly fixed, unless their diameter was determined prior to implantation with respect to the fixation on the example sulcus ciliaris.
  • the annular shape of known implants and the typically rigid tabs disadvantageously set relatively narrow limits with respect to an optimal dimensioning for the fixation.
  • the tabs in the plane of the disc ring must not be extended arbitrarily, as this has dimensional instabilities of the implant, in particular a potentially tissue-damaging bulge result.
  • the tabs to ensure fixation must have a minimum length in the plane of the disc ring, since the implant would otherwise be insufficiently fixed.
  • the danger associated with the known implants of a defective fixation can have fatal consequences for a patient.
  • migration and / or rotation of the known implants may occur after implantation, in that they and, if appropriate, the sensor attached to them, together with the telemetry unit, penetrate the eye tissue and / or the iris.
  • Shadowing the optical axis of the eye are possible consequences.
  • the present invention is therefore based on the object to provide an implant of the type mentioned, which, circumventing the disadvantages of the prior art, an improved fixation, in particular with regard to the naturally occurring variability of the anatomical conditions of the eye allows.
  • the implant is transverse to the optical axis of the eye
  • the implant is transverse to the optical axis of the eye
  • non-positively by means of, for example, a biasing force and / or by means of at least one positive connection between the
  • fabric structure is meant any structure that is capable of doing so
  • Implant according to the invention with respect to the optical axis of the eye on the fixing means, which may for example consist of pressure-elastic springs with arcuate sections to fix. That in particular, the structure which is formed in the posterior chamber of the eye by the anatomical groove between the ciliary body and the iris root, so the sulcus ciliaris, so that the contact element, which may for example be in the form of an arcuate portion of a compression spring, at the bottom of this anatomical Furrow stores, so contacted, for example, the furrow ground.
  • the fixing means which may for example consist of pressure-elastic springs with arcuate sections to fix. That in particular, the structure which is formed in the posterior chamber of the eye by the anatomical groove between the ciliary body and the iris root, so the sulcus ciliaris, so that the contact element, which may for example be in the form of an arcuate portion of a compression spring, at the bottom of this anatomical Furrow stores, so contacted, for example
  • Implant avoided because the implant according to the invention with respect to the optical axis of the eye, and in particular can be fixed transversely to the optical axis of the eye.
  • implant according to the invention over the contact element, so for example a portion of a surgical thread, but also on a
  • Tissue structure are fixed in the anterior chamber of the eye, namely preferably in the iridocorenal chamber angle. This is
  • the fixing means comprise at least one deflection element for deflecting the abutment element in a deflection plane, the deflection plane being positioned in the implanted state perpendicular to the optical axis of the eye.
  • the deflection element which, for example, as an adjusting element in the form of a set screw or as elastic spring may be configured, a deflection of the deflection element
  • Abutment element transversely to the optical axis of the eye reached, so that the intended by the contact element fixation of the implant according to the invention, so for example the storage of a temple section of a compression spring on the furrow bottom of the suicus ciliaris, for example, the naturally occurring diameter spectrum of the suicus ciliaris covers. That is to say, by means of the deflection element, the implant according to the invention is suitable, for example, for fixation in patients with relatively small as well as in patients with relatively large suicus ciliaris. With advantage for the practice therefore the storage of different accounts
  • implant according to the invention is also positioned perpendicular to the optical axis of the eye, the storage of the contact element and thus the fixation negatively influencing occurrence of torques is minimized in the implant according to the invention with advantage, after which the implant according to the invention with advantage mainly by
  • Implant provides that the deflection element has a reminderformbarkeit after deformation of the deflection element, wherein the
  • the deflection element so for example an elastic compression spring with arcuate sections, in such a way automatically, ie without or almost no intervention of a doctor performing, for example, such unfold, that the contact element, so for example a wavy structured portion of a spring, transversely to the direction of the optical axis, for example, the furrow bottom of the suicus ciliaris moves until it comes to a contact between the contact element and the furrow bottom of the suicus ciliaris.
  • implant according to the invention in small-scale technique using a relatively simple or standard injector for intraocular lenses can be implanted particularly simple and secure (parameters of the so-called clear corneal technique, ⁇ 3.5 Millimeters or preferably
  • the advantages associated with the implant according to the invention also manifest themselves in the fact that the deformability of the deflecting element, ie, for example, the deflection of a deformed spring consisting of a polymer with shape memory properties after a certain switching temperature has been exceeded, a nearly universal adaptation of the contact element, so for example bow-shaped section of a spring, to the anatomical conditions of the eye, in particular the diameter of the suicus ciliaris allows.
  • a with regard to the fixation of the implant according to the invention preoperative dimensioning is therefore eliminated with advantage. Because even modern equipped clinics often do not have the necessary for an exact measurement of the anatomical conditions of the eye such as the diameter of the suicus ciliaris
  • the jerk deformability is elastic.
  • the deflector may be, for example, a mechanical spring. That is, with advantage for the fixation of the implant according to the invention causes a caused by the spring elastic biasing force in the fold bottom of, for example, sulcus ciliaris for a local attachment of the
  • An implant according to the invention may also be designed so that the recoverability is stimulable via a stimulus. With advantage for the implanting of the implant according to the invention, the recoverability can therefore be switchable.
  • stimulus is therefore meant any external stimulus that causes a shape memory effect in a suitable material. Consequently, the deflecting element of the implant according to the invention can advantageously be implanted in a deformed state such that, after a doctor performing the implanting has reached a suitable position for fixing the inventive device
  • Implant such as the sulcus ciliaris, the deflecting element unfolds in a fixation-favorable manner due to a shape memory effect produced by a stimulus such as a UV light pulse.
  • the stimulus is a variation of
  • Shape memory polymer existing spring as a deflection in the serve implant according to the invention. If the shape memory polymer is heated above a composition-specific temperature, a re-deformation of the spring takes place, ie a deflection of the exemplary deflection element such that its contact element attaches, for example, to the fold bottom of the sulcus ciliaris.
  • the shape memory effect known from metals is also advantageously applicable in that the deflection element of the implant according to the invention consists of such a metal.
  • the deflection element and / or the contact element consists of a polymer. This is in terms of a possible trauma-free
  • the deflection element so for example a polymer thread, and / or the contact element, ie, for example, a portion of the polymer thread as an example, dimensional stability and at the same time not weakening the eye tissue elastic compliance.
  • the deflecting element and / or the contact element at least partially from a
  • the implant according to the invention can advantageously be introduced, for example, into a tube-like injector for the implanted implant of the implant according to the invention.
  • the deflection element that is to say a thread made of a shape memory polymer, unfolds on the basis of a
  • Shape memory effect in accordance with a provided for the fixation of the implant shape, so for example a curved shape, so that the contact element on, for example, the furrow bottom of the sulcus ciliaris stores.
  • Crosslinking of polymer chains a change in shape of the deflection element on a macroscopic scale, in particular of the order of magnitude
  • the deflection element is formed to be bulge in the direction perpendicular to the deflection plane. This is in terms of a possible trauma-free fixation of the invention
  • Implant ensures that the deflection, so
  • the resilient portions are, for example, in the deflection, in the implanted state does not bulge along the optical axis of the eye, possibly to
  • Investment element is designed at least partially arcuate. This has a positive effect on the deformability of the deflecting element which is preferred for implanting the implant according to the invention or the elastic compliance of the abutment element required for injury-free implantation, for example the arcuate section of a compression spring made of a shape-memory polymer.
  • deflection elements and / or abutment elements are particularly preferred a sectionally C- and / or Z-shaped sections lying in the deflection plane.
  • the abutment element has a segmented surface on a surface provided for contacting with the tissue structure, that is to say, for example, the surface of an arcuate section of a compression spring
  • the surface structure of the abutment element can therefore have, for example, steps whose abutment surfaces rest against the step surfaces of the sulcus ciliaris formed by membranous segmentations in the tangential direction to the approximately circular periphery defined by the sulcus ciliaris, after which the implant according to the invention additionally prevents rotation about the optical axis of the abutment Eye is fixed.
  • the implant according to the invention is particularly advantageous for the positive connection of the contact element with the sulcus ciliaris
  • the implant has holding means, wherein the holding means are designed for holding at least one sensor and / or a telemetry unit in the holder plane and with the deflecting element in FIG
  • the holding means may be, for example, a perforated plate, on which, for example, a pressure sensor for measuring intraocular pressure and / or a sensor for measuring of the glucose level and / or a temperature sensor for
  • Temperaturnnessung can be fixed by means of, for example, an adhesive connection.
  • the transmission of the data measured by the sensor can take place via an induction coil of a telemetry unit to an external receiver, which is located outside the eye.
  • the implant according to the invention can be used by means of the holding means for monitoring clinical parameters of the eye such as, for example, intraocular pressure.
  • Holding means and the contact element with respect to the normal of the deflection plane spaced from each other can be arranged.
  • the holding means that is, for example, one for holding a pressure sensor and one
  • Induction coil provided plate with a rail frame, are positioned by the usually near the iris preferred place of implantation with respect to the optical axis of the eye as far away.
  • implant according to the invention can be reduced.
  • the sulcus ciliaris is in the place of fixation.
  • the implant according to the invention spatially from the support means which lie in the implant according to the invention in a mounting plane, which is arranged with respect to the optical axis of the eye of the iris farther away than the contact element, along the optical axis of the eye in the implanted state.
  • the implant according to the invention can advantageously be fixed with respect to an iris not injuring implant both in the posterior chamber of the eye, namely in the sulcus ciliaris, as well as in the anterior chamber of the eye, namely in iridocorenal chamber angle.
  • the deflection element lies in at least one section in an inclination plane, the inclination plane and the deflection plane being angled relative to each other. The section of the
  • Deflection element for example, the central portion of a wire-shaped compression spring, thus protrudes out of the deflection plane in the implant according to the invention due to the mutually angled inclination plane and deflection plane. In this way can be in the
  • the implant according to the invention has a particularly advantageous spatial separation between the support means operatively connected to the deflecting element, for example a plate glued to one end of a compression spring, and the deflecting plane, ie for example the plane lying in the groove bottom of the sulcus ciliaris , just realize that
  • Implanted sensor according to the invention and the iris is minimized.
  • the support means in the direction transverse to the optical axis of the eye from the optical axis of the eye can be arranged spaced apart. In an advantageous manner are therefore in the
  • implant according to the invention for example, a plate
  • the fixing means can be fastened by means of releasable fastening means.
  • releasable fastening means for example, latching elements are meant, so that designed for example as a bending wire fixing means to Engage one end of the wire in the example designed as a frame member holding means.
  • the implant according to the invention can therefore be modularly composed of the fixing means, that is, for example, a bending wire, and the holding means, that is, for example, a frame.
  • Implantation the modules, namely the fixation means and the support means, implant independently to connect them intraocularly by means of the latching elements, which allows, for example, smaller surgical incisions for access to the anterior chamber of the eye than in known implants.
  • the holding means are integrally formed with the sensor and / or the telemetry unit as a polymer casting. Accordingly, the implant according to the invention can advantageously be embedded in a, for example, silicone rubber matrix for minimally invasive implantation.
  • Figure 1 Top view in the direction along the optical axis of a
  • FIG. 2 section of the implant according to FIG. 1 along the line II
  • FIG. 1 perspective view of an implant according to the invention in a further preferred embodiment
  • FIG. 15 a sectional view of an implant according to the invention in a further preferred embodiment
  • FIG. 16 is a schematic plan view of an implant according to FIG
  • FIG. 17 is a schematic top view of an implant according to FIG. 17
  • FIG. 1 shows in the direction of view along the optical axis 1 of an eye 2 a plan view of the eye 2 with an artificial lens 3 and an implanted implant 4 according to a preferred embodiment of the invention.
  • the implant 4 consists of two bent compression springs 5 and one with the compression springs 5 integrally formed plate 6, which is connected via a non-illustrated adhesive connection with a sensor telemetry module also not shown for measuring
  • FIG. 2 shows a sectional view of the implant 4 from FIG. 1.
  • the compression springs 5 deform back to an elastic deformation in a plane 9, which is perpendicular to the optical axis 1, to the extent that the bow section 8 of the compression springs 5 is pressed against the groove bottom 7 of the sulcus ciliaris 68, after which the implant 4 is fixed transversely to the direction of the optical axis 1.
  • FIGS. 3 to 6 show different representations of a further implant 10 according to the invention. Analogous to the implant 4 of Figures 1 and 2, the implant 10 according to Figures 3 to 6 of two compression springs 1 1 and one with the compression springs 1 1 in one piece
  • the plate 12 is connected via a non-illustrated adhesive connection with a sensor telemetry module 13. Adhesive has flowed into the liquid state in the holes of the plate 13 shown in FIG. 5, so that the sensor telemetry module 13 is additionally anchored to the plate 13 via the adhesive subsequently hardened in the holes.
  • the compression springs 11 are designed in an angulated manner in a middle section 14. As a result, storable bracket sections 15 of the compression springs 11 are spatially separated from the plate 12 and thus the sensor telemetry modules 13 along a direction 16 shown in FIG. 6 at the groove bottom of the sulcus ciliaris (not illustrated in FIGS. 3 to 6).
  • Feathers 1 1 fix that the strap sections 15 along the optical axis of the eye (see Figure 2) are arranged closer to the iris, as the plate 12 and the sensor telemetry module 13 of the implant 10. In an analogous manner can thus be the implant 10 also in the
  • FIG. 7 is a schematic representation of three implants 17, 18 and 19 according to the invention, each in a further preferred embodiment
  • the implant 17 has, in addition to a plate 27 compression springs 20 and 26, whose elastic recovery according to the implant of Figures 1 and 2 and Figures 3-6 causes a fixation of the implant 17 in the furrow bottom of the sulcus ciliaris.
  • the mean radius of curvature of the compression spring 26 is greater than the average radius of curvature of the compression spring 20, thereby it is possible that the provided for a sensor telemetry module plate 27 can be positioned as far outside the optical axis in the implanted state.
  • the implant 18 is next to a plate 28 of a compression spring 21 and a compression spring 22, wherein the mean radius of curvature of the compression spring 21 is greater than the average radius of curvature of the compression spring 22.
  • the compression springs 20 and 26 of the implant 17 Compared to the compression springs 20 and 26 of the implant 17, however the difference between the
  • Curvature radii of the compression springs 21 and 22 to each other less.
  • the implant 19 in addition to a plate 29 of three compression springs 23, 24 and 25.
  • the compression springs 24 and 25 are arranged opposite of the compression spring 23.
  • the radius of curvature of the compression spring 23 is greater than the radius of curvature of the compression springs 24 and 25.
  • FIG. 8 shows a representation of an implant 30 in a further preferred embodiment according to the invention.
  • the implant 30 consists of a perforated plate 31 and compression springs 32 with provided for attachment to the furrow bottom of the sulcus ciliaris bracket portions 33 which are deflected by an elastic recovery of the compression springs 32 in the direction of the sulcus ciliaris.
  • FIG. 9 shows a sectional view of the implant 30 from FIG. 8. The sectional view from FIG.
  • FIG. 9 shows that in the case of the implant 30 a pressure sensor 34, together with an induction coil 35, which telemetrically transmits measurement data acquired by the pressure sensor to a receiver, of a polymer matrix 36 is surrounded, so that the pressure sensor 34, the induction coil 35 and the plate 31 are present as a one-piece device in the implant 30.
  • the polymer matrix 36 could flow in the liquid state into the holes of the plate 31, after which the pressure sensor 34 and the induction coil 35 via the
  • Polymer matrix 36 is anchored in the holes of the plate 31 with the plate 31.
  • the polymer matrix 36 consists of silicone rubber.
  • FIG. 10 shows a schematic plan view of a further implant 37 according to the invention.
  • the implant 37 consists of compression springs 39 shaped analogously to the implants of FIGS. 1 to 9 and a frame 38 which is open on one side and in which, according to FIG. 10
  • Silicone rubber embedded pressure sensor 41 including an induction coil 42 is supported.
  • the polymer matrix 40 has therefore been introduced into the frame 38 on the open side of the frame 38.
  • the implant 37 is thus modular, namely a module consisting of the
  • Compression springs 39 and the frame 38 and a removable from the frame 38 module consisting of the pressure sensor 41 and the induction coil comprising polymer matrix 40 made of silicone rubber.
  • FIG. 12 shows a schematic plan view of a further implant 43 according to the invention with a frame 44 which, in contrast to the frame 38 of the implant 37 according to FIGS. 10 and 11, is circumferentially closed.
  • a polymer matrix 45 is mounted in which a pressure sensor 46 and an induction coil 47 are embedded.
  • FIG. 13 shows that the polymer matrix 45 is mounted in a form-fitting manner in the frame 44 of the implant 43 either by means of a groove (FIG. 13 above), or that the frame 44 is completely embedded in the polymer matrix 42 (FIG Center) or that the frame 44 is partially embedded in the polymer matrix 45 (Figure 13 below) by placing a rail 47 of the frame outside the polymer matrix ( Figure 13 below).
  • FIG. 14 is a sectional view of an implant 48, in which a pressure sensor 49 and a planar coil 50 serving as a telemetry unit are embedded together with a holding frame 51 in a polymer matrix 52.
  • FIG. 15 shows a sectional view of an implant 54 designed analogously to the implant 48 from FIG. 14, but in which a coil 53 is embedded in a polymer matrix 55.
  • FIG. 16 shows in plan view a schematic representation of an implant 56 according to the invention, in which a one-piece compression spring 57, which consists of a thread, on a section 58 into a
  • Polymer matrix 59 is embedded together with a coil 60 and a pressure sensor 61.
  • the implant 56 has a particularly compact and thus advantageous for implantation construction.
  • FIG. 17 of a schematically illustrated implant 62 shows that the implant 62 consists of plate 67 and two springs 63 and 64.
  • the spring 63 has, in a bow section 65, a wave-shaped structure which as a result is suitable for attaching to the sulcus ciliaris having membranous segmentations.
  • the spring 64 of the implant 62 has a tooth-shaped structure in a bracket section 66, which in particular serves to fix the Implant 62 against a rotation about an optical axis, not shown, of the eye is particularly well suited.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention vise à fournir un implant (4, 10, 17, 18, 19, 30, 37, 43, 48, 54, 56, 62) destiné à être implanté dans et/ou sur un œil (2) à l'aide de moyens de fixation (5, 11, 20, 21, 22, 23, 24, 25, 26, 32, 39, 57, 63, 64), ledit implant permettant une meilleure fixation, en particulier en ce qui concerne la variabilité naturelle des spécificités anatomiques de l'œil (2). L'invention propose à cet effet que les moyens de fixation (5, 11, 20, 21, 22, 23, 24, 25, 26, 32, 39, 57, 63, 64) présentent au moins un élément d'installation (8, 15, 33, 65, 66) pouvant être placé sur une structure tissulaire (7) transversalement par rapport à l'axe optique (1) de l'œil (2).
PCT/EP2017/077697 2016-10-28 2017-10-27 Implant intraoculaire WO2018078144A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2019522811A JP7104694B2 (ja) 2016-10-28 2017-10-27 眼内インプラント
AU2017348634A AU2017348634A1 (en) 2016-10-28 2017-10-27 Intraocular implant
CA3039583A CA3039583A1 (fr) 2016-10-28 2017-10-27 Implant intraoculaire
EP17791677.2A EP3547900A1 (fr) 2016-10-28 2017-10-27 Implant intraoculaire

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102016221368.7A DE102016221368A1 (de) 2016-10-28 2016-10-28 Intraokulares Implantat
DE102016221368.7 2016-10-28

Publications (1)

Publication Number Publication Date
WO2018078144A1 true WO2018078144A1 (fr) 2018-05-03

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ID=60191389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/077697 WO2018078144A1 (fr) 2016-10-28 2017-10-27 Implant intraoculaire

Country Status (6)

Country Link
EP (1) EP3547900A1 (fr)
JP (1) JP7104694B2 (fr)
AU (1) AU2017348634A1 (fr)
CA (1) CA3039583A1 (fr)
DE (1) DE102016221368A1 (fr)
WO (1) WO2018078144A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562600A (en) * 1983-10-18 1986-01-07 Stephen P. Ginsberg Intraocular lens
US4704125A (en) * 1985-08-05 1987-11-03 Ruminson Wallace E Intraocular lens for posterior chamber implantation
US20140107459A1 (en) * 2012-10-11 2014-04-17 Alcon Research, Ltd. Devices, systems, and methods for intraocular measurements

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL161706A0 (en) * 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US20120004528A1 (en) * 2010-07-02 2012-01-05 Alcon Research, Ltd. Implantable Remote Monitoring Sensor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562600A (en) * 1983-10-18 1986-01-07 Stephen P. Ginsberg Intraocular lens
US4704125A (en) * 1985-08-05 1987-11-03 Ruminson Wallace E Intraocular lens for posterior chamber implantation
US20140107459A1 (en) * 2012-10-11 2014-04-17 Alcon Research, Ltd. Devices, systems, and methods for intraocular measurements

Also Published As

Publication number Publication date
DE102016221368A1 (de) 2018-05-03
JP2019532762A (ja) 2019-11-14
JP7104694B2 (ja) 2022-07-21
EP3547900A1 (fr) 2019-10-09
AU2017348634A1 (en) 2019-05-23
CA3039583A1 (fr) 2018-05-03

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