WO2018059177A1 - 移动式癫痫病治疗仪及癫痫病治疗系统 - Google Patents

移动式癫痫病治疗仪及癫痫病治疗系统 Download PDF

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WO2018059177A1
WO2018059177A1 PCT/CN2017/099656 CN2017099656W WO2018059177A1 WO 2018059177 A1 WO2018059177 A1 WO 2018059177A1 CN 2017099656 W CN2017099656 W CN 2017099656W WO 2018059177 A1 WO2018059177 A1 WO 2018059177A1
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patient
mobile
epilepsy
epilepsy treatment
information
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PCT/CN2017/099656
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English (en)
French (fr)
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赵一赫
诺敏
赵桂强
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赵一赫
诺敏
赵桂强
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/14Leading-off electric charges, e.g. by earthing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects

Definitions

  • the invention relates to the technical field of medical technology, in particular to a mobile epilepsy therapeutic apparatus and an epilepsy treatment system.
  • the common treatment methods for epilepsy at home and abroad are mainly divided into three categories: 1) drug therapy for epilepsy; 2) surgical treatment of epilepsy; 3) ketogenic diet therapy.
  • Surgical treatment mainly includes: 1 resection surgery: lesion resection, lesion resection, (multiple) lobe resection, cerebral hemisphere resection, selective hippocampus-amygdala resection; 2 dissection surgery: single lobe Or multi-brain segmentation surgery, cerebral hemisphere disconnection; 3 palliative surgery: corpus callosum, multiple subdural transection, cortical electrocoagulation; 4 stereotactic radiotherapy: epilepsy Radiation therapy, conduction path radiotherapy; 5 stereotactic radiofrequency lesions for epileptogenic radiation therapy, conduction pathway radiotherapy; 6 neuromodulation surgery: using implantable and non-implantable techniques, relying on regulating electrical activity or chemical delivery The quality of the means to achieve control or reduce the purpose of seizures, neuromodulation surgery is somewhat reversible relative to
  • Surgical treatment of epilepsy is a major advancement in modern medicine and an effective treatment for patients with drug-refractory epilepsy, which can completely eliminate seizures in more than half of patients.
  • epilepsy surgery has strict surgical indications. A rigorous evaluation is required before the operation, and for patients who are suitable for surgery, individualized surgical plans should be developed according to the specific conditions of the patients.
  • VNS Vagus Nerve Stimulation
  • Vagus nerve stimulation is an adjuvant therapy approved by the US Food and Drug Administration as a refractory epilepsy.
  • the principle is to implant the stimulator into the superficial layer of the pectoralis major under the left supraclavicular bone.
  • the stimulator electrode is fixed to the cervical vagus nerve.
  • the chest wall stimulator continuously emits weak electrical impulses, stimulating the vagus nerve, thereby causing changes in brain electrical activity and neurotransmitters, and achieving the purpose of treating epilepsy.
  • Clinical studies have shown that vagus nerve stimulation can achieve complete control of approximately 10% of patients with refractory epilepsy. As the implantation time is extended, the number of episodes can be reduced by more than 50% by continuously adjusting the stimulation parameters.
  • VNS vagus nerve stimulation
  • refractory epilepsy a kind of therapy also has an effect on improving the quality of life of patients, which can make patients' vigilance, language skills, thinking ability, independence and other aspects get different degrees of progress.
  • VNS vagus nerve stimulation
  • surgical treatment including vagus nerve stimulation can be used as appropriate, and most can achieve good results.
  • the purpose of the surgery is to control the seizure to the greatest extent, but the surgery is not suitable for everyone, and not everyone can achieve no seizures at all.
  • the brain is traumatic, and the minimally invasive surgery is also traumatic.
  • the trauma may also stimulate abnormal discharge in the surrounding area. Therefore, it is necessary to regularly use the drug after surgery, that is, the surgical treatment has its risk.
  • the cost is also relatively high.
  • ketogenic diet treatment through a high-fat, low-carbohydrate and appropriate protein diet to achieve therapeutic purposes, treatment of refractory epilepsy in children, the mechanism of anti-epilepsy is still unclear.
  • the embodiment of the invention provides a mobile epilepsy treatment device, which solves the technical problem of recurrent episodes of epilepsy treatment in the prior art, physical injury or risk to the patient.
  • the mobile epilepsy treatment apparatus comprises: a superconducting plate sensor for contacting the head of the patient, and the current generated by the discharge of the brain neuron is derived outside the patient, and the discharge of the cranial nerve causes an epileptic seizure.
  • the embodiment of the invention further provides an epilepsy treatment system for solving the technical problems of recurrent episodes in the treatment of epilepsy in the prior art, physical injury or risk to the patient.
  • the epilepsy treatment system comprises: at least one of the above-mentioned mobile epilepsy treatment devices; a computer for acquiring and storing position information, current information and patient information of each mobile epilepsy treatment instrument.
  • FIG. 1 is a schematic diagram of a mobile epilepsy treatment apparatus according to an embodiment of the present invention.
  • FIG. 2 is a schematic view showing the installation of a micro-recorder on a mobile epilepsy treatment apparatus according to an embodiment of the present invention
  • FIG. 3 is a structural block diagram of an epilepsy treatment system according to an embodiment of the present invention.
  • the mobile epilepsy treatment apparatus in the embodiment of the present invention includes:
  • the superconducting plate sensor 101 is configured to contact the skull of the patient, and the current generated by the discharge of the brain neuron is derived outside the patient, and the discharge of the brain neuron causes an epileptic seizure.
  • the current generated by the discharge of the brain neuron is derived from the patient's head through the superconducting plate sensor, and the inventor finds that the root cause of the epileptic seizure is the cranial nerve. The abnormal abnormality of the element and the synchronous discharge activity are caused. Therefore, the inventor proposes to contact the patient's skull through the superconducting plate sensor, and the current generated by the discharge of the brain neuron is derived outside the patient, and the brain neurons are restored to achieve treatment and prevention. The purpose of epilepsy.
  • the treatment method can prevent the body injury or the risk of epilepsy treatment, and can effectively prevent epileptic seizures and avoid recurrent seizures; and the mobile epilepsy
  • the disease treatment device is easy to use and suitable for all people. Everyone can achieve the purpose of effectively treating and preventing epilepsy. It is suitable for group prevention and group treatment, which can help alleviate the suffering of patients with epilepsy, improve patient independence and quality of life. .
  • the mobile epilepsy treatment apparatus further includes: a bracket 102 for fixing the superconducting plate sensing Device
  • the shape of the stent is adapted to the shape of the patient's skull.
  • the superconducting plate sensor 101 is fixed on the bracket 102.
  • the bracket 102 may be formed by two arc-shaped structures being cross-fixed.
  • the shape of the bracket 102 is adapted to the shape of the patient's skull, and the superconducting is superconducting.
  • the plate sensor 101 is respectively fixed at the end and the top end of the bracket 102.
  • the patient In the case that the emotional condition, the physical state, the climate change, etc. can cause the patient to be ill, the patient only needs to wear the bracket 102 on the head, and the superconducting plate sensor 101 can be Contact with the patient's head to derive the current generated by the discharge of brain neurons out of the patient's body for the purpose of treating and preventing epilepsy.
  • the number of the superconducting plate sensors may be five, which are respectively in contact with the left temporal lobe acupoint, the right temporal lobe acupoint, the frontal acupoint, the occipital acupoint, and the parietal acupoint of the patient's skull.
  • the left axillary acupoint, the right temporal lobe acupoint, the frontal acupoint, the occipital acupoint and the parietal acupoint are the points where the abnormal discharge of brain neurons leads to a higher frequency of epileptic seizures, in order to improve treatment and prevention.
  • the success rate of epilepsy the inventors proposed that in the left temporal lobe acupoint, right temporal lobe acupoint, frontal acupoint, occipital acupoint and apical acupoints, there are superconducting plate sensor contacts, cranial nerves of any acupoint The abnormal discharge occurs in the element, and the superconducting plate sensor can timely discharge the current to the outside of the patient to improve the reliability of the above-mentioned mobile epilepsy treatment instrument.
  • the superconducting plate sensor 101 includes: a current sensor for sensing an instantaneous current generated when the brain neuron is discharged, acquiring the current information; and a melt for using the cranial nerve
  • the instantaneous current generated during the discharge of the element is derived outside the patient, consuming the instantaneous current.
  • the current sensor senses an instantaneous current generated when the brain neuron is discharged, and obtains current information.
  • the current information may include a magnitude of the instantaneous current, a frequency at which the discharge generates an instantaneous current, a time when the discharge generates an instantaneous current, and
  • the information about the instantaneous current generated by the discharge of the brain neurons of the acupoint, the current information may be in the form of an electroencephalogram image; the melt utilizes the principle of electromagnetic induction to derive the instantaneous current generated by the discharge of the inner deep brain neuron into the patient's body, and instantaneously The current is consumed.
  • the mobile epilepsy treatment apparatus further includes: a micro recorder 103 connected to the superconducting plate sensor, The current information sensed by the superconducting plate sensor is collected in real time, and the collected current information is stored corresponding to the patient information.
  • the micro recorder is connected to the superconducting plate sensor. If the mobile epilepsy device has the holder 102 as shown in FIG. 1 and the superconducting plate sensor 101 is fixed to the end and the top end of the holder 102, the micro recorder The 103 can be fixed to the bracket 102. For example, as shown in FIG.
  • the micro recorder 103 can be fixed in front of the top end of the bracket 102, and the connecting line of the superconducting plate sensor 101 and the micro recorder 103 can be disposed inside the bracket 102.
  • the micro recorder can take current information from the current sensor of the superconducting plate sensor 101 in real time, and the current information and the patient The information is stored correspondingly.
  • the patient information may include information such as patient name, gender, age, family address, date, time, medical record number, temperature and humidity of the environment in which the patient is located, and store real-time current information and patient information.
  • the patient can query the storage record, analyze the environmental factors or self-factors during the epileptic seizure, and can autonomously pre-wear the above-mentioned mobile epilepsy treatment instrument in order to effectively treat and prevent epilepsy. attack.
  • doctors can also check the storage records, analyze the patient's condition and provide a reliable treatment basis for further treatment.
  • the micro recorder includes: a USB interface for deriving stored current information and patient information; and/or a wireless transmission device for transmitting stored current information and patient information. .
  • the micro-recorder further includes: a solar battery, configured to convert solar energy into electrical energy, and provide power to the micro-recorder.
  • the micro recorder further includes: a positioning device, configured to locate position information of the patient. Specifically, after locating the patient's location information, a geographic location basis can be provided for analyzing the patient's condition.
  • the mobile epilepsy treatment device further includes: a cryptographic device, receiving preset password information input by the user, triggering activation of the superconducting plate sensor.
  • a cryptographic device receiving preset password information input by the user, triggering activation of the superconducting plate sensor.
  • each mobile epilepsy treatment device is provided with a preset password information, and only the preset password information is correctly input, and the password device receives the preset password information input by the user, so that the mobile epilepsy can be activated.
  • the therapeutic device works, and the superconducting plate sensor can be triggered by a signal triggering method.
  • the foregoing cryptographic device can be implemented in the form of a logic circuit.
  • the mobile epilepsy treatment device further includes: a casing, the superconducting plate sensing
  • the device is disposed in the housing, and the housing is in the shape of a hat.
  • the superconducting plate sensor is disposed in the housing, and the patient can wear the mobile epilepsy treatment device like a hat, so that the patient looks like a normal person in the dress, and has achieved aesthetics and eliminates the psychological pressure of the patient.
  • the housing can be shaped into any hat according to the specific needs of the patient.
  • the superconducting plate sensor is fixed on the bracket as shown in FIG. 1 , and a fixing strap can be disposed inside the casing to fix the bracket in the casing, thereby further superconducting the plate.
  • the inductor, the micro-recorder, and the like are fixed in the casing, and a rectangular opening, for example, a 1.5 cm ⁇ 4 cm opening may be opened in the casing, so that the solar cell of the micro-recorder receives the solar energy through the opening, thereby being a micro-recorder. powered by.
  • an epilepsy treatment system is further provided.
  • the system includes: at least one of the above-mentioned mobile epilepsy treatment apparatuses; a computer for acquiring and Store each move Location information, current information, and patient information.
  • the function of the patient database can be realized on the computer side, which provides a basis for the analysis and summary of the medical records, and provides a convenient and rapid diagnosis, treatment and tracking procedure for the epilepsy patients, so as to achieve an accurate and complete data link for the individuals with epilepsy. Service and retain data for life.
  • a computer can obtain the following information from various mobile epilepsy devices by wired or wireless means: a) seasonal factors of the patient in four seasons at home and abroad (such as sunny days, foggy days, rainy days, cloudy days, snowy days, etc.) The incidence rate; b) the incidence of different genders, including the age group, the area where the patient is located (such as plains, highlands, cities, rural areas, etc.); c) individual differences in epilepsy patients, such as blood type, personality (introversion) , extroverted), personal hobbies, habits, etc.; d) the time period of each epileptic seizure discharge, the amount of current, etc.; e) the location of the discharge and the number of discharges.
  • seasonal factors of the patient in four seasons at home and abroad such as sunny days, foggy days, rainy days, cloudy days, snowy days, etc.
  • the incidence rate b) the incidence of different genders, including the age group, the area where the patient is located (such as plains, highlands
  • the current generated by the discharge of the brain neuron is derived from the patient's head through the superconducting plate sensor, and the inventors find that the root cause of the epileptic seizure is abnormal abnormality of the brain neurons and synchronized discharge.
  • the inventors proposed to contact the patient's skull through a superconducting plate sensor, and to derive the current generated by the discharge of brain neurons from the patient's body and restore the brain neurons to achieve the purpose of treating and preventing epilepsy.
  • the treatment method can prevent the body injury or the risk of epilepsy treatment, and can effectively prevent epileptic seizures and avoid recurrent seizures; and the mobile epilepsy
  • the disease treatment device is suitable for everyone, and everyone can achieve effective treatment and prevention of epilepsy.
  • embodiments of the present invention can be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment, or a combination of software and hardware. Moreover, the invention can take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) including computer usable program code.
  • computer-usable storage media including but not limited to disk storage, CD-ROM, optical storage, etc.
  • the computer program instructions can also be stored in a computer readable memory that can direct a computer or other programmable data processing device to operate in a particular manner, such that the instructions stored in the computer readable memory produce an article of manufacture comprising the instruction device.
  • the apparatus implements the functions specified in one or more blocks of a flow or a flow and/or block diagram of the flowchart.
  • These computer program instructions can also be loaded onto a computer or other programmable data processing device such that a series of operational steps are performed on a computer or other programmable device to produce computer-implemented processing for execution on a computer or other programmable device.
  • the instructions provide steps for implementing the functions specified in one or more of the flow or in a block or blocks of a flow diagram.

Abstract

本发明实施例提供了一种移动式癫痫病治疗仪及癫痫病治疗系统,其中,该移动式癫痫病治疗仪包括:超导电板感应器,用于与患者头颅接触,将脑神经元放电产生的电流导出患者体外,所述脑神经元放电导致癫痫病发作。该方案通过超导电板感应器与患者头颅接触的方式来将脑神经元放电产生的电流导出患者体外,患者可以随时、自主地将超导电板感应器与头颅接触,实现不吃药、不手术的治疗方式,可以避免癫痫病治疗给患者带来身体伤害或风险,还可以有效预防癫痫病发作,避免癫痫病的反复发作。

Description

移动式癫痫病治疗仪及癫痫病治疗系统 技术领域
本发明涉及医疗技术领域,尤其涉及一种移动式癫痫病治疗仪及癫痫病治疗系统。
背景技术
目前,国内外对癫痫病的常用治疗方法主要分为三大类:1)癫痫的药物治疗;2)癫痫外科治疗;3)生酮饮食治疗。
针对1)癫痫的药物治疗,以镇静剂类药物为主,长期服用以达到控制病情发作的手段,但是,药物对人体有伤害,药物不良反应容易引起脑痴呆等患病风险。癫痫病的发作无时间规律,且部分患者因长期服药导致药耐受效果不佳。
针对2)癫痫外科治疗(包括神经调控疗法),手术只是癫痫的治疗方法之一,一般术后还是要规范用药。外科治疗主要包括:①切除性手术:病灶切除术、致病灶切除术、(多)脑叶切除性、大脑半球切除术、选择性海马-杏仁核切除术;②离断性手术:单脑叶或多脑叶离断手术、大脑半球离断术;③姑息性手术:胼胝体切开术、多处软膜下横切术、脑皮层电凝热灼术;④立体定向放射治疗术:致痫灶放射治疗、传导通路放射治疗;⑤立体定向射频毁损术致痫灶放射治疗、传导通路放射治疗;⑥神经调控手术:利用植入性和非植入性技术手段,依靠调节电活动或化学递质的手段,来达到控制或减少癫痫发作的目的,神经调控手术相对于切除性手术的有点是可逆、治疗参数可体外调整及创伤小。目前癫痫常用的神经调控手术有:迷走神经刺激术、脑深部电刺激术、反应式神经电刺激术、微量泵的植入技术及经颅磁刺激等。
通过外科手术治疗癫痫,是现代医学的一大进步,是药物难治性癫痫患者的有效治疗方法,可以使一半以上患者的癫痫发作完全消失。但是,癫痫外科手术治疗,有严格的手术适应症。手术之前需要进行严格的评估,对于适合手术的患者,还要根据患者的具体情况,制订个体化的手术方案。
例如,迷走神经刺激术(Vagus Nerve Stimulation,简称为VNS)是一种新的治疗难治性癫痫的有效外科手段,它具有不用开颅、不损伤脑神经组织、微创、可逆、安全性高等优点,自应用于临床以来受到广泛欢迎。不但可以用于药物无效的患者,对于手术后无效或复发者也适合进行此手术治疗。
迷走神经刺激术(VNS)是美国食品及药品管理局批准作为难治性癫痫的辅助疗法,其原理是将刺激器植入左锁骨下的胸大肌浅层,刺激器电极固定于颈部迷走神经,胸壁刺激器不断发射微弱电脉冲,刺激迷走神经,从而引起脑电活动及神经递质变化,达到治疗癫痫的目的。临床研究结果显示,迷走神经刺激术可以使大约10%难治性癫痫患者获得完全控制,随着植入时间的延长,通过不断调整刺激参数,大约70%患者发作次数可减少50%以上。值得一提的是,这种疗法对于改善患者的生活质量也有作用,可以使患者的警觉性、语言技巧、思维能力、独立性等方面,获得不同程度的进步。目前,国内外迷走神经刺激术(VNS)在儿童以及成人难治性癫痫患者中的应用越来越广泛,对儿童的记忆力、情志改善尤为明显。随着研究的深入,VNS已经广泛应用于无法进行切除性手术的各种年龄段难治性癫痫患者。除了药物治疗以外,可以酌情采用包括迷走神经刺激术在内的外科治疗手段,大多数可以取得良好疗效。
但是,外科手术治疗癫痫存在以下缺陷:
首先,手术的目的是最大程度地控制发作,但手术并不适合所有人,并不是每个人都能达到完全不发作。
其次,手术毕竟对大脑有创伤,再微创的手术也是有创伤的,创伤也可能刺激周围区域异常放电,因此,术后还是要规律用药,即外科治疗有其风险性。费用也比较高。
最后,手术不是一劳永逸,手术治疗后还需要辅助药物治疗。
针对3)生酮饮食治疗,是通过一个高脂、低碳水化合物和适当蛋白质的饮食来达到治疗的目的,治疗儿童难治性癫痫,其抗癫痫的机制目前还不清楚。
发明内容
本发明实施例提供一种移动式癫痫病治疗仪,以解决现有技术中癫痫病治疗存在的反复发作、对患者有身体伤害或风险的技术问题。该移动式癫痫病治疗仪包括:超导电板感应器,用于与患者头颅接触,将脑神经元放电产生的电流导出患者体外,所述脑神经元放电导致癫痫病发作。
本发明实施例还提供一种癫痫病治疗系统,以解决现有技术中癫痫病治疗存在的反复发作、对患者有身体伤害或风险的技术问题。该癫痫病治疗系统包括:至少一台上述任意一种移动式癫痫病治疗仪;计算机,用于获取并存储每台移动式癫痫病治疗仪的位置信息、电流信息和患者信息。
附图说明
为了更清楚地说明本发明实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。在附图中:
图1为本发明实施例中的一种移动式癫痫病治疗仪示意图;
图2为本发明实施例中的一种微型记录器在移动式癫痫病治疗仪上的安装示意图;
图3为本发明实施例中的一种癫痫病治疗系统结构框图。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚明白,下面结合附图对本发明实施例做进一步详细说明。在此,本发明的示意性实施例及其说明用于解释本发明,但并不作为对本发明的限定。
图1为本发明实施例中的移动式癫痫病治疗仪的示意图。如图1所示,本发明实施例中的移动式癫痫病治疗仪包括:
超导电板感应器101,用于与患者头颅接触,将脑神经元放电产生的电流导出患者体外,所述脑神经元放电导致癫痫病发作。
由图1所示可知,在本发明实施例中,通过超导电板感应器与患者头颅接触,将脑神经元放电产生的电流导出患者体外,由于发明人发现癫痫病发作的根本原因是脑神经元异常过度、同步化放电活动所造成的,因此,发明人提出通过超导电板感应器与患者头颅接触,将脑神经元放电产生的电流导出患者体外,恢复脑神经元,以达到治疗和预防癫痫病的目的。由于是通过超导电板感应器与患者头颅接触的方式来将脑神经元放电产生的电流导出患者体外,患者可以随时、自主地将超导电板感应器与头颅接触,实现不吃药、不手术的治疗方式,与现有技术中的癫痫病治疗相比,可以避免癫痫病治疗给患者带来身体伤害或风险,还可以有效预防癫痫病发作,避免癫痫病的反复发作;同时该移动式癫痫病治疗仪使用方便、适合所有人使用,每个人可以达到有效治疗和预防癫痫病的目的,适合群防、群治人群,有助于减轻癫痫病患者的痛苦、提高患者的独立性和生活质量。
具体实施时,为了方便患者佩戴上述移动式癫痫病治疗仪,在本实施例中,如图1所述,上述移动式癫痫病治疗仪还包括:支架102,用于固定所述超导电板感应器,所 述支架的形状与所述患者头颅的形状相适应。例如,超导电板感应器101固定在支架102上,如图1所示,支架102可以是两个弧形结构交叉固定形成的,支架102的形状与所述患者头颅的形状相适应,超导电板感应器101分别固定在支架102的末端和顶端,在情绪情况、身体状态、气候变化等能引起自身犯病的情况下,患者只要将支架102佩戴在头上,超导电板感应器101即可与患者的头颅接触,以便将脑神经元放电产生的电流导出患者体外,达到治疗和预防癫痫病的目的。
具体实施时,由于导致癫痫病发作的异常放电的脑神经元在大脑中的部位不同,且脑神经元异常放电具有突发性和瞬时性,为了提高上述移动式癫痫病治疗仪的可靠性,在本实施例中,上述超导电板感应器的数量可以为5个,分别与患者头颅的左颞叶穴位、右颞叶穴位、额叶穴位、枕叶穴位以及顶叶穴位接触。发明人发现左颞叶穴位、右颞叶穴位、额叶穴位、枕叶穴位以及顶叶穴位这5个区域是发生脑神经元异常放电导致癫痫病发作频率较高的点,为了提高治疗和预防癫痫病的成功率,发明人提出在左颞叶穴位、右颞叶穴位、额叶穴位、枕叶穴位以及顶叶穴位这5个点分别有超导电板感应器接触,任意一个穴位的脑神经元发生异常放电,超导电板感应器都能及时将电流导出患者体外,以提高上述移动式癫痫病治疗仪的可靠性。
具体实施时,所述超导电板感应器101,包括:电流感应器,用于感应所述脑神经元放电时产生的瞬时电流,获取所述电流信息;熔体,用于将所述脑神经元放电时产生的瞬时电流导出患者体外,消耗所述瞬时电流。具体的,电流感应器感应脑神经元放电时产生的瞬时电流,获取电流信息,例如,该电流信息可以包括瞬时电流的大小、发生放电产生瞬时电流的频率、发生放电产生瞬时电流的时间以及是哪个穴位的脑神经元放电产生的瞬时电流等信息,该电流信息可以是脑电图像的形式;熔体利用电磁感应原理,将内部深层脑神经元放电产生的瞬时电流导出患者体外,并将瞬时电流消耗掉。
具体实施时,为了便于查询患者的病情信息,在本实施例中,如图2所示,上述移动式癫痫病治疗仪还包括:微型记录器103,与所述超导电板感应器连接,用于实时采集所述超导电板感应器感应到的电流信息,将采集的电流信息与患者信息对应存储。具体的,微型记录器与超导电板感应器连接,如果移动式癫痫病治疗仪具有如图1所示的支架102,超导电板感应器101固定在支架102的末端和顶端,则微型记录器103可以固定在支架102上,例如,如图2所示,微型记录器103可以固定在支架102的顶端前方,超导电板感应器101与微型记录器103的连接线可以设置在支架102内部,微型记录器可以实时从超导电板感应器101的电流感应器处获取电流信息,并将电流信息与患 者信息对应存储,例如,该患者信息可以包括患者姓名、性别、年龄、家庭地址、年月日、时间、病历号、患者所处环境的温湿度等信息,将实时电流信息与患者信息对应存储后,患者可以查询存储记录,分析自身癫痫病发作时的环境因素或自身因素,在再次出现相似的发病因素时可以自主地预先佩戴上述移动式癫痫病治疗仪,以便有效治疗和预防癫痫病的发作。同时,医生也可以查询存储记录,分析患者的病情发展,为进一步的治疗提供可靠的治疗依据。
具体实施时,在本实施例中,所述微型记录器,包括:USB接口,用于导出存储的电流信息和患者信息;和/或,无线传输设备,用于传输存储的电流信息和患者信息。
具体实施时,在本实施例中,所述微型记录器,还包括:太阳能电池,用于将太阳能转化为电能,为所述微型记录器提供电源。
具体实施时,在本实施例中,所述微型记录器,还包括:定位设备,用于定位患者的位置信息。具体的,定位患者的位置信息后,可以为分析患者的病情提供地理位置依据。
具体实施时,在本实施例中,上述移动式癫痫病治疗仪还包括:密码设备,接收用户输入的预设密码信息,触发所述超导电板感应器启动。例如,每台移动式癫痫病治疗仪都设有一个预设密码信息,只有该预设密码信息被正确输入了,密码设备接收到用户输入的预设密码信息,才能启动该台移动式癫痫病治疗仪工作,可以通过信号触发的方式触发超导电板感应器启动。具体的,上述密码设备可以通过逻辑电路的形式实现。
具体实施时,为了使得上述移动式癫痫病治疗仪具有美观性,消除患者佩戴时的心理压力,在本实施例中,上述移动式癫痫病治疗仪还包括:壳体,所述超导电板感应器设置于所述壳体内,所述壳体为帽子形状。具体的,上述超导电板感应器设置于壳体内,患者可以像戴帽子一样佩戴上述移动式癫痫病治疗仪,使得患者在着装上看起来跟正常人一样,已达到美观、消除患者心理压力的目的。该壳体可以根据患者具体需求做成任意帽子的形状。当上述移动式癫痫病治疗仪具有支架时,超导电板感应器固定在如图1所示的支架上,在壳体内侧可以设置固定带,以便将支架固定在壳体内,进而将超导电板感应器、微型记录器等固定在壳体内,还可以在壳体上开设长方形开口,例如,1.5厘米×4厘米的开口,以便微型记录器的太阳能电池通过该开口接收太阳能,进而为微型记录器供电。
具体实施时,在本实施例中,还提供了一种癫痫病治疗系统,如图3所示,该系统包括:至少一台上述任意一种移动式癫痫病治疗仪;计算机,用于获取并存储每台移动 式癫痫病治疗仪的位置信息、电流信息和患者信息。在该计算机端可以实现患者数据库的功能,为病案分析、总结提供依据,给癫痫病患者提供了普查普治方便快捷的诊断、治疗、跟踪程序,实现对癫痫病患者个体达到精确完整的数据链服务并终身保留数据。例如,计算机可以通过有线或无线的方式从各台移动式癫痫病治疗仪获取以下信息:a)患者在国内外四个季节中季节因素(如晴天、雾天、雨天、阴天、雪天等)导致的发病率;b)男女性别不同的发病率,包括年龄段、患者所处地区(如平原、高原、城市、农村等);c)癫痫病患者的个体差异,如血型、性格(内向、外向)、个人嗜好、习惯等;d)每次癫痫病发作放电的时间段、电流量等;e)经常在哪个部位放电及放电数量原因等。
目前,治愈癫痫病还是一个世界难题。尽管最近十多年医学技术快速发展,治疗癫痫病的药物和手术方式都有很大的发展和进步,但是想要治愈癫痫病,目前还是很困难。发明人找到癫痫病发作的根本原因是由于异常放电的脑神经元在大脑中的部位不同,且脑神经元异常放电具有突发性和短暂一过性,发明人采取与现有外科手术治疗的逆向思维,提出上述移动式癫痫病治疗仪、癫痫病治疗系统。
另外,具体资料显示:①居世界卫生组织(World Health Organization,简称为WHO)估计,全球大约有5000万癫痫病患者。国内流行病学资料显示,我国癫痫病的患病率(prevalence)在4%~7%之间。近年来,国内外学者更重视活动性癫痫的患病率,即在最近某段时间(1年或2年)内仍有发作的癫痫病列数与同期人口之比,我国活动性癫痫患病率为4.6%,年发病率在30/10万左右。据此估算,我国约有600万左右的活动性癫痫病患者,同时每年有40万左右新发癫痫病患者。癫痫病是神经内科最常见的疾病之一。癫痫病患者的死亡危险性为一般人群的2~3倍。②我国目前处于经济快速发展阶段和经济转轨期,医疗保险、就业等社会保证体系还不十分完善,目前在癫痫诊疗实践中存在着许多不足和不规范之处。③癫痫病患者因病情原因多数没有正式工作,没有参加社保,目前癫痫病也不在医保范围内。针对癫痫病患者数量庞大的现状,本申请的移动式癫痫病治疗仪、癫痫病治疗系统具有积极意义,起到群防、群治效果,给个人、家庭和社会带来福音。
在本发明实施例中,通过超导电板感应器与患者头颅接触,将脑神经元放电产生的电流导出患者体外,由于发明人发现癫痫病发作的根本原因是脑神经元异常过度、同步化放电活动所造成的,因此,发明人提出通过超导电板感应器与患者头颅接触,将脑神经元放电产生的电流导出患者体外,恢复脑神经元,以达到治疗和预防癫痫病的目的。 由于是通过超导电板感应器与患者头颅接触的方式来将脑神经元放电产生的电流导出患者体外,患者可以随时、自主地将超导电板感应器与头颅接触,实现不吃药、不手术的治疗方式,与现有技术中的癫痫病治疗相比,可以避免癫痫病治疗给患者带来身体伤害或风险,还可以有效预防癫痫病发作,避免癫痫病的反复发作;同时该移动式癫痫病治疗仪适合所有人使用,每个人可以达到有效治疗和预防癫痫病的目的。
本领域内的技术人员应明白,本发明的实施例可提供为方法、系统、或计算机程序产品。因此,本发明可采用完全硬件实施例、完全软件实施例、或结合软件和硬件方面的实施例的形式。而且,本发明可采用在一个或多个其中包含有计算机可用程序代码的计算机可用存储介质(包括但不限于磁盘存储器、CD-ROM、光学存储器等)上实施的计算机程序产品的形式。
本发明是参照根据本发明实施例的方法、设备(系统)、和计算机程序产品的流程图和/或方框图来描述的。应理解可由计算机程序指令实现流程图和/或方框图中的每一流程和/或方框、以及流程图和/或方框图中的流程和/或方框的结合。可提供这些计算机程序指令到通用计算机、专用计算机、嵌入式处理机或其他可编程数据处理设备的处理器以产生一个机器,使得通过计算机或其他可编程数据处理设备的处理器执行的指令产生用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的装置。
这些计算机程序指令也可存储在能引导计算机或其他可编程数据处理设备以特定方式工作的计算机可读存储器中,使得存储在该计算机可读存储器中的指令产生包括指令装置的制造品,该指令装置实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能。
这些计算机程序指令也可装载到计算机或其他可编程数据处理设备上,使得在计算机或其他可编程设备上执行一系列操作步骤以产生计算机实现的处理,从而在计算机或其他可编程设备上执行的指令提供用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的步骤。
以上所述的具体实施例,对本发明的目的、技术方案和有益效果进行了进一步详细说明,所应理解的是,以上所述仅为本发明的具体实施例而已,并不用于限定本发明的保护范围,凡在本发明的精神和原则之内,所做的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。

Claims (11)

  1. 一种移动式癫痫病治疗仪,其特征在于,包括:
    超导电板感应器,用于与患者头颅接触,将脑神经元放电产生的电流导出患者体外,所述脑神经元放电导致癫痫病发作。
  2. 如权利要求1所述的移动式癫痫病治疗仪,其特征在于,还包括:
    支架,用于固定所述超导电板感应器,所述支架的形状与所述患者头颅的形状相适应。
  3. 如权利要求1所述的移动式癫痫病治疗仪,其特征在于,所述超导电板感应器的数量为5个,分别与患者头颅的左颞叶穴位、右颞叶穴位、额叶穴位、枕叶穴位以及顶叶穴位接触。
  4. 如权利要求1至3中任一项所述的移动式癫痫病治疗仪,其特征在于,还包括:
    微型记录器,与所述超导电板感应器连接,用于实时采集所述超导电板感应器感应到的电流信息,将采集的电流信息与患者信息对应存储。
  5. 如权利要求4所述的移动式癫痫病治疗仪,其特征在于,所述微型记录器,包括:
    通用串行总线接口,用于导出存储的电流信息和患者信息;和/或
    无线传输设备,用于传输存储的电流信息和患者信息。
  6. 如权利要求4所述的移动式癫痫病治疗仪,其特征在于,所述微型记录器,还包括:
    太阳能电池,用于将太阳能转化为电能,为所述微型记录器提供电源。
  7. 如权利要求4所述的移动式癫痫病治疗仪,其特征在于,所述微型记录器,还包括:
    定位设备,用于定位患者的位置信息。
  8. 如权利要求4所述的移动式癫痫病治疗仪,其特征在于,所述超导电板感应器,包括:
    电流感应器,用于感应所述脑神经元放电时产生的瞬时电流,获取所述电流信息;
    熔体,用于将所述脑神经元放电时产生的瞬时电流导出患者体外,消耗所述瞬时电流。
  9. 如权利要求1至3中任一项所述的移动式癫痫病治疗仪,其特征在于,还包括:
    壳体,所述超导电板感应器设置于所述壳体内,所述壳体为帽子形状。
  10. 如权利要求1至3中任一项所述的移动式癫痫病治疗仪,其特征在于,还包括:
    密码设备,接收用户输入的预设密码信息,触发所述超导电板感应器启动。
  11. 一种癫痫病治疗系统,其特征在于,包括:
    至少一台如权利要求1至10中任一项所述的移动式癫痫病治疗仪;
    计算机,用于获取并存储每台移动式癫痫病治疗仪的位置信息、电流信息和患者信息。
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