WO2018051295A3 - Non-saponifiable compounds of natural lipids for use in the treatment of tumour pathologies - Google Patents

Non-saponifiable compounds of natural lipids for use in the treatment of tumour pathologies Download PDF

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Publication number
WO2018051295A3
WO2018051295A3 PCT/IB2017/055623 IB2017055623W WO2018051295A3 WO 2018051295 A3 WO2018051295 A3 WO 2018051295A3 IB 2017055623 W IB2017055623 W IB 2017055623W WO 2018051295 A3 WO2018051295 A3 WO 2018051295A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
chronic
saponifiable
natural
steroidal
Prior art date
Application number
PCT/IB2017/055623
Other languages
French (fr)
Other versions
WO2018051295A2 (en
Inventor
Chiara De Gregorio
Original Assignee
Codex V Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codex V Srl filed Critical Codex V Srl
Publication of WO2018051295A2 publication Critical patent/WO2018051295A2/en
Publication of WO2018051295A3 publication Critical patent/WO2018051295A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to the use of non-saponifiable moieties obtained from natural, plant and/or animal lipids, for the treatment of tumour diseases caused by the permanent (or chronic) alteration (or imbalance) of the normal physiological equilibrium of the steroidal balance in a patient suffering from this chronic condition. In particular, the invention relates to a pharmaceutical composition comprising said non-saponifiable moieties for use in the treatment of those tumour diseases, lung tumours and/or vulvar tumors and/or mammary tumors and/or shell carcinomas and/or melanomas, which are caused by permanent (or chronic) alteration (or unbalance) of the natural physiological equilibrium of the steroidal balance in a patient suffering from said pathology, and of the chronic lesions associated with the same which determine them. Said pharmaceutical composition is particularly adapted for transdermal and/or transmucosal topical administration.
PCT/IB2017/055623 2016-09-19 2017-09-18 Non—saponifiable compounds of natural lipids for use in the treatment of tumour pathologies WO2018051295A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102016000093758A IT201600093758A1 (en) 2016-09-19 2016-09-19 UNSAPONIFYABLE OF NATURAL LIPIDS FOR USE IN THE TREATMENT OF TUMOR PATHOLOGIES
IT102016000093758 2016-09-19

Publications (2)

Publication Number Publication Date
WO2018051295A2 WO2018051295A2 (en) 2018-03-22
WO2018051295A3 true WO2018051295A3 (en) 2018-06-07

Family

ID=57960603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2017/055623 WO2018051295A2 (en) 2016-09-19 2017-09-18 Non—saponifiable compounds of natural lipids for use in the treatment of tumour pathologies

Country Status (2)

Country Link
IT (1) IT201600093758A1 (en)
WO (1) WO2018051295A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1010072B (en) * 2019-05-15 2021-09-15 Αριστοτελειο Πανεπιστημιο Θεσσαλονικης - Ειδικος Λογαριασμος Κονδυλιων Ερευνας Edible veterinary intramammary teat sealant formulations and method for their preparation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037848A1 (en) * 1999-11-29 2001-05-31 Rimonest Ltd. Mixture of pomegranate seed oil and juice products
US20020012710A1 (en) * 1999-11-29 2002-01-31 Rimonest Ltd. Pomegranate products useful in improving health and methods of use thereof
US20070243233A1 (en) * 2006-04-18 2007-10-18 Naturi Llc Bioactive-rich concentrates and nutritive and therapeutic products containing same
CN102441012A (en) * 2011-11-15 2012-05-09 江苏大学 Golden mushroom saponifiable extract product with antitumor effect, preparation method and application thereof
CN103054908A (en) * 2011-11-17 2013-04-24 江苏大学 Unsaponifiable extract with antitumor action in flammulina velutipes, and preparation method and application thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037848A1 (en) * 1999-11-29 2001-05-31 Rimonest Ltd. Mixture of pomegranate seed oil and juice products
US20020012710A1 (en) * 1999-11-29 2002-01-31 Rimonest Ltd. Pomegranate products useful in improving health and methods of use thereof
US20070243233A1 (en) * 2006-04-18 2007-10-18 Naturi Llc Bioactive-rich concentrates and nutritive and therapeutic products containing same
CN102441012A (en) * 2011-11-15 2012-05-09 江苏大学 Golden mushroom saponifiable extract product with antitumor effect, preparation method and application thereof
CN103054908A (en) * 2011-11-17 2013-04-24 江苏大学 Unsaponifiable extract with antitumor action in flammulina velutipes, and preparation method and application thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 201240, Derwent World Patents Index; AN 2012-F92223, XP002779271 *
DATABASE WPI Week 201366, Derwent World Patents Index; AN 2013-P86270, XP002768677 *

Also Published As

Publication number Publication date
IT201600093758A1 (en) 2018-03-19
WO2018051295A2 (en) 2018-03-22

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