WO2018045499A1 - Système de diagnostic basé sur l'onde de pouls comprenant une fonction de collecte d'onde respiratoire - Google Patents

Système de diagnostic basé sur l'onde de pouls comprenant une fonction de collecte d'onde respiratoire Download PDF

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Publication number
WO2018045499A1
WO2018045499A1 PCT/CN2016/098275 CN2016098275W WO2018045499A1 WO 2018045499 A1 WO2018045499 A1 WO 2018045499A1 CN 2016098275 W CN2016098275 W CN 2016098275W WO 2018045499 A1 WO2018045499 A1 WO 2018045499A1
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WIPO (PCT)
Prior art keywords
wave
pulse wave
respiratory
pulse
sensor
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PCT/CN2016/098275
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English (en)
Chinese (zh)
Inventor
侯洁娜
张海英
耿兴光
张以涛
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中国科学院微电子研究所
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Priority to PCT/CN2016/098275 priority Critical patent/WO2018045499A1/fr
Publication of WO2018045499A1 publication Critical patent/WO2018045499A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs

Definitions

  • the present invention relates to a pulse wave diagnostic system, and more particularly to a pulse wave diagnostic system that combines respiratory wave acquisition.
  • the pulse wave is formed by the periodic pulsation of the heart along the arterial blood vessels and blood flow to the periphery.
  • the process of pulse wave propagation is not only affected by the heart itself, but also by the condition of the arteries and surrounding tissues and organs along the way, and contains abundant physiological and pathological information of the human body.
  • pulse wave non-invasive detection technology the study of pulse wave has attracted the attention of Chinese and foreign medical circles.
  • the traditional Chinese medicine diagnosis pulse while obtaining the pulse information through the pulse, uses the pulse between the breath and the pulse as the diagnostic criteria for the pulse wave pulsation. There are "four to five to three, three to late, six to the number”. Said. One of them is a breath. It can be seen that the collection of respiratory waves has important clinical significance for the diagnosis of pulse of traditional Chinese medicine.
  • the current pulse wave diagnosis system generally only collects pulse waves through sensors, and extracts time domain or frequency domain characteristic parameters according to the amplitude and time characteristics of the pulse wave, and does not include respiratory wave information.
  • Such a pulse diagnosis system can not reproduce the pulse diagnosis basis of the traditional pulse diagnosis, which is not conducive to the accurate diagnosis of the pulse, and to a certain extent hinders the comprehensive and in-depth study of the pulse wave.
  • a pulse wave diagnosis system having respiratory wave acquisition comprising a pulse wave sensor, a respiratory wave acquiring device, a processing device, and a diagnostic device, wherein the pulse wave sensor is configured to collect a pulse wave of a person to be tested;
  • the acquisition device is used to obtain the pulse of the person to be tested Wave-synchronized respiratory wave;
  • the processing device is configured to extract time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave;
  • the diagnostic device is configured to obtain a pulse diagnosis result according to the characteristic parameter.
  • the pulse wave sensor is a pulse wave sensor that performs pulse wave acquisition at a single position in a certain area of the human body outside a certain period of time.
  • the pulse wave sensor is an array type pulse wave sensor that performs pulse wave synchronous acquisition at a plurality of positions in a certain area of the human body outside a certain period of time, including a pressure sensor, and performs non-invasive multi-point on a certain area of the human body surface.
  • a multi-array pulse wave sensor for synchronous acquisition of pulse waves.
  • the respiratory wave acquiring device is a sensor that performs synchronous acquisition of respiratory waves while acquiring a pulse wave of a person to be tested.
  • the respiratory wave acquisition device is a sensor that acquires a respiratory wave based on a chest displacement using a non-contact Doppler radar or a respiratory chest strap, or a sensor that acquires a respiratory wave using a impedance method based on a sputum impedance measurement.
  • the respiratory wave acquiring device may be an extractor that extracts a synchronized respiratory wave signal from a pulse signal, and extracts a respiratory wave signal from the pulse wave using a correlation algorithm such as Fourier transform or EMD algorithm.
  • the processing device extracts time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave using a correlation algorithm such as a Fourier transform or an EMD algorithm.
  • the diagnostic device is a device that can give rhythm "on the fly” and other respiratory related pulse diagnostic information.
  • FIG. 1 is a structural diagram of a pulse wave diagnostic system having respiratory wave acquisition according to the present invention
  • FIG. 2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention
  • FIG. 3 is a pulse wave diagnostic system that combines respiratory wave acquisition in accordance with an embodiment of the present invention. Waveforms of pulse wave and respiratory wave interaction obtained by the system;
  • FIG. 4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • the implementation path of the present invention is as follows:
  • FIG. 1 a structural diagram of a pulse wave diagnosis system having respiratory wave acquisition according to the present invention.
  • the first aspect of the invention relates to a pulse wave diagnosis system with respiratory wave acquisition.
  • the pulse wave sensor is used to collect the pulse wave of the person to be tested, and the pulse wave sensor is used to perform a single position in a certain area of the human body outside the body within a certain period of time. Pulse wave acquisition, or the use of an array pulse wave sensor for pulse wave simultaneous acquisition at multiple locations in a region of the human body.
  • the second aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention uses a respiratory wave acquisition device to acquire a synchronized respiratory wave of a person to be tested.
  • the pulse wave sensor performs pulse wave acquisition while using a non-contact type. Synchronous acquisition of respiratory waves by sensors such as Pule radar or respiratory chest straps that acquire respiratory waves based on thoracic displacement, or chest impedance based on impedance method
  • the sensor that acquires the respiratory wave is used for synchronous acquisition of the respiratory wave, and the other method is used for synchronous acquisition of the respiratory wave; the other is to use the synchronous respiratory wave signal extractor to process the pulse wave data collected by the pulse wave sensor, and extract the breathing in the pulse wave signal.
  • the wave signal realizes the acquisition of the respiratory wave signal.
  • the third aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention is to analyze and process pulse wave and respiratory wave data by using a processing device, and to perform processing such as filtering and denoising the pulse wave signal and the respiratory wave signal, using Fourier transform.
  • Algorithms such as EMD extract time-domain and frequency-domain characteristic parameters of pulse waves and respiratory waves.
  • a fourth aspect of the pulse wave diagnosis system of the invention having respiratory wave acquisition is to use a diagnostic device to give a pulse wave diagnosis result with respiratory wave data, which is based on the analysis result of the pulse wave and the respiratory wave signal, according to the traditional Chinese medicine.
  • the pulse diagnosis theory gives pulse diagnosis information such as pulse potential, pulse length, intensity, and rhythm “every minute”.
  • FIG. 2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • step S101 information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
  • step S102 the pulse wave of the person to be tested is collected and the respiratory wave of the person to be tested is synchronously collected.
  • a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain area of the human body surface; while a pulse wave is collected, a non-contact Doppler radar or a respiratory chest is used. Synchronously collect the respiratory wave of the person to be tested, and store the synchronized pulse wave and respiratory wave data.
  • the pulse wave and respiratory wave data are processed in step S103.
  • the synchronous pulse wave and the respiratory wave signal collected in S102 are processed by filtering and denoising, and the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave are extracted by using algorithms such as Fourier transform and EMD.
  • FIG. 3 is a waveform diagram of a pulse wave and a respiratory wave interaction relationship obtained by a pulse wave diagnosis system having respiratory wave acquisition according to an embodiment of the present invention.
  • S201 is a pulse wave waveform
  • S202 is a pulse wave.
  • Synchronous respiratory wave waveform according to the pulse wave data processing result in S103, the time interval T 1 of the pulse wave data stabilization is selected; according to the result of the synchronous respiratory wave data processing in S103, the time interval T 2 of the respiratory wave data stabilization is selected; T 3 is a pulse wave stabilizing time T.
  • Pulse wave diagnosis information is derived from all the data in step S105. For example, the information of the personal information of the person to be tested and the date and time of collection recorded in S101, and the data processing results of the pulse wave and the respiratory wave in S103, and the pulse wave number information between the information obtained in S104, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
  • FIG. 4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • step S301 information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
  • the pulse wave of the person to be tested is collected in step S302.
  • a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain region of the human body surface, and store pulse wave data.
  • the pulse wave is subjected to data processing and a respiratory wave is extracted in step S303.
  • a respiratory wave is extracted from the pulse wave using an algorithm such as Fourier transform or EMD.
  • EMD Fourier transform
  • the pulse wave and the extracted respiratory wave are further processed to acquire the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave.
  • step S304 a pulse wave and a respiratory wave interaction relationship such as "a few moments" are obtained.
  • S201 is the acquired pulse wave waveform
  • S202 is a respiratory wave waveform extracted from the pulse wave after data processing on the pulse wave, and pulse wave is selected according to the pulse wave data processing result in S303.
  • T 3 is the pulse wave stabilization time T 1 and the respiratory wave stabilization time period T 2 overlapping portions; data further processed to obtain the time interval T the pulse beats. 3 N 1, and the time interval T the number of breaths. 3 N 2; information can be obtained between the pulse wave to a number of N 1 / N 2 .
  • other respiratory waves and pulse waves can be derived.
  • Pulse wave diagnosis information is derived from all the data in step S305. For example, the information of the personal information of the person to be tested recorded in S301 and the date and time of collection, and the data processing results of the pulse wave and the respiratory wave in S303, and the pulse wave number information between the information obtained in S304, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
  • the pulse wave diagnosis system having the respiratory wave acquisition of the present invention and a method of using the same for diagnosis have been fully described.
  • the system can restore the traditional diagnosis mode and obtain more comprehensive physiological information as the basis for pulse wave diagnosis. It not only provides the possibility of accurate diagnosis of pulse wave, but also provides in-depth study of pulse wave. A new idea.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un système de diagnostic basé sur l'onde de pouls comprenant une fonction de collecte d'onde respiratoire, comprenant un capteur d'onde de pouls, un dispositif d'acquisition d'onde respiratoire, un dispositif de traitement et un dispositif de diagnostic. Le capteur d'onde de pouls est utilisé pour collecter l'onde de pouls d'une personne à détecter ; le dispositif d'acquisition d'onde respiratoire est utilisé pour acquérir l'onde respiratoire de la personne à détecter qui est synchrone avec l'onde de pouls ; le dispositif de traitement est utilisé pour extraire des paramètres caractéristiques de domaine temporel et de domaine fréquentiel de l'onde de pouls et de l'onde respiratoire ; et le dispositif de diagnostic est utilisé pour obtenir un résultat de diagnostic de l'état du pouls fondé sur les paramètres caractéristiques. Le système de diagnostic peut donner une corrélation entre l'onde respiratoire et l'onde de pouls telle que "plusieurs battements dans un cycle respiratoire" et des informations analogues par traitement des signaux d'onde respiratoire et d'onde de pouls obtenus, de telle sorte que l'extraction d'informations physiologiques associées au pouls est plus complète, ce qui ouvre de nouvelles possibilités pour les études de l'onde de pouls, en particulier de la relation entre l'onde de pouls et la fonction cardiopulmonaire.
PCT/CN2016/098275 2016-09-07 2016-09-07 Système de diagnostic basé sur l'onde de pouls comprenant une fonction de collecte d'onde respiratoire WO2018045499A1 (fr)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111084618A (zh) * 2019-12-13 2020-05-01 安徽通灵仿生科技有限公司 一种可穿戴式多功能呼吸循环检测系统及方法
CN111449638A (zh) * 2020-04-08 2020-07-28 上海祉云医疗科技有限公司 一种基于传感器采集的数据构建三维脉象图的方法及应用
CN114722855A (zh) * 2022-02-28 2022-07-08 太原理工大学 一种滑脉波的识别处理方法

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CN101073495A (zh) * 2007-06-15 2007-11-21 东华大学 嵌入服装式人体亚健康智能评估装置及方法
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CN104138253A (zh) * 2013-05-11 2014-11-12 吴健康 一种无创动脉血压连续测量方法和设备
US20140364750A1 (en) * 2013-06-11 2014-12-11 Intelomend, Inc. Methods and systems for predicting hypovolemic hypotensive conditions resulting from bradycardia behavior using a pulse volume waveform
CN104921715A (zh) * 2015-06-09 2015-09-23 上海华旌科技有限公司 一种多参数生命体征测量装置
CN106308769A (zh) * 2016-09-07 2017-01-11 中国科学院微电子研究所 一种兼具呼吸波采集的脉搏波诊断系统

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Publication number Priority date Publication date Assignee Title
CN101073495A (zh) * 2007-06-15 2007-11-21 东华大学 嵌入服装式人体亚健康智能评估装置及方法
CN102046076A (zh) * 2008-04-03 2011-05-04 Kai医药公司 非接触式生理运动传感器及其使用方法
CN104138253A (zh) * 2013-05-11 2014-11-12 吴健康 一种无创动脉血压连续测量方法和设备
US20140364750A1 (en) * 2013-06-11 2014-12-11 Intelomend, Inc. Methods and systems for predicting hypovolemic hypotensive conditions resulting from bradycardia behavior using a pulse volume waveform
CN104083147A (zh) * 2014-07-04 2014-10-08 上海赛诚医药科技有限公司 中医诊断系统
CN104921715A (zh) * 2015-06-09 2015-09-23 上海华旌科技有限公司 一种多参数生命体征测量装置
CN106308769A (zh) * 2016-09-07 2017-01-11 中国科学院微电子研究所 一种兼具呼吸波采集的脉搏波诊断系统

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111084618A (zh) * 2019-12-13 2020-05-01 安徽通灵仿生科技有限公司 一种可穿戴式多功能呼吸循环检测系统及方法
CN111449638A (zh) * 2020-04-08 2020-07-28 上海祉云医疗科技有限公司 一种基于传感器采集的数据构建三维脉象图的方法及应用
CN114722855A (zh) * 2022-02-28 2022-07-08 太原理工大学 一种滑脉波的识别处理方法

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