WO2018045499A1 - Pulse wave diagnostic system having respiratory wave collection function - Google Patents

Pulse wave diagnostic system having respiratory wave collection function Download PDF

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WO2018045499A1
WO2018045499A1 PCT/CN2016/098275 CN2016098275W WO2018045499A1 WO 2018045499 A1 WO2018045499 A1 WO 2018045499A1 CN 2016098275 W CN2016098275 W CN 2016098275W WO 2018045499 A1 WO2018045499 A1 WO 2018045499A1
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wave
pulse wave
respiratory
pulse
sensor
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PCT/CN2016/098275
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French (fr)
Chinese (zh)
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侯洁娜
张海英
耿兴光
张以涛
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中国科学院微电子研究所
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Priority to PCT/CN2016/098275 priority Critical patent/WO2018045499A1/en
Publication of WO2018045499A1 publication Critical patent/WO2018045499A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs

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  • the present invention relates to a pulse wave diagnostic system, and more particularly to a pulse wave diagnostic system that combines respiratory wave acquisition.
  • the pulse wave is formed by the periodic pulsation of the heart along the arterial blood vessels and blood flow to the periphery.
  • the process of pulse wave propagation is not only affected by the heart itself, but also by the condition of the arteries and surrounding tissues and organs along the way, and contains abundant physiological and pathological information of the human body.
  • pulse wave non-invasive detection technology the study of pulse wave has attracted the attention of Chinese and foreign medical circles.
  • the traditional Chinese medicine diagnosis pulse while obtaining the pulse information through the pulse, uses the pulse between the breath and the pulse as the diagnostic criteria for the pulse wave pulsation. There are "four to five to three, three to late, six to the number”. Said. One of them is a breath. It can be seen that the collection of respiratory waves has important clinical significance for the diagnosis of pulse of traditional Chinese medicine.
  • the current pulse wave diagnosis system generally only collects pulse waves through sensors, and extracts time domain or frequency domain characteristic parameters according to the amplitude and time characteristics of the pulse wave, and does not include respiratory wave information.
  • Such a pulse diagnosis system can not reproduce the pulse diagnosis basis of the traditional pulse diagnosis, which is not conducive to the accurate diagnosis of the pulse, and to a certain extent hinders the comprehensive and in-depth study of the pulse wave.
  • a pulse wave diagnosis system having respiratory wave acquisition comprising a pulse wave sensor, a respiratory wave acquiring device, a processing device, and a diagnostic device, wherein the pulse wave sensor is configured to collect a pulse wave of a person to be tested;
  • the acquisition device is used to obtain the pulse of the person to be tested Wave-synchronized respiratory wave;
  • the processing device is configured to extract time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave;
  • the diagnostic device is configured to obtain a pulse diagnosis result according to the characteristic parameter.
  • the pulse wave sensor is a pulse wave sensor that performs pulse wave acquisition at a single position in a certain area of the human body outside a certain period of time.
  • the pulse wave sensor is an array type pulse wave sensor that performs pulse wave synchronous acquisition at a plurality of positions in a certain area of the human body outside a certain period of time, including a pressure sensor, and performs non-invasive multi-point on a certain area of the human body surface.
  • a multi-array pulse wave sensor for synchronous acquisition of pulse waves.
  • the respiratory wave acquiring device is a sensor that performs synchronous acquisition of respiratory waves while acquiring a pulse wave of a person to be tested.
  • the respiratory wave acquisition device is a sensor that acquires a respiratory wave based on a chest displacement using a non-contact Doppler radar or a respiratory chest strap, or a sensor that acquires a respiratory wave using a impedance method based on a sputum impedance measurement.
  • the respiratory wave acquiring device may be an extractor that extracts a synchronized respiratory wave signal from a pulse signal, and extracts a respiratory wave signal from the pulse wave using a correlation algorithm such as Fourier transform or EMD algorithm.
  • the processing device extracts time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave using a correlation algorithm such as a Fourier transform or an EMD algorithm.
  • the diagnostic device is a device that can give rhythm "on the fly” and other respiratory related pulse diagnostic information.
  • FIG. 1 is a structural diagram of a pulse wave diagnostic system having respiratory wave acquisition according to the present invention
  • FIG. 2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention
  • FIG. 3 is a pulse wave diagnostic system that combines respiratory wave acquisition in accordance with an embodiment of the present invention. Waveforms of pulse wave and respiratory wave interaction obtained by the system;
  • FIG. 4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • the implementation path of the present invention is as follows:
  • FIG. 1 a structural diagram of a pulse wave diagnosis system having respiratory wave acquisition according to the present invention.
  • the first aspect of the invention relates to a pulse wave diagnosis system with respiratory wave acquisition.
  • the pulse wave sensor is used to collect the pulse wave of the person to be tested, and the pulse wave sensor is used to perform a single position in a certain area of the human body outside the body within a certain period of time. Pulse wave acquisition, or the use of an array pulse wave sensor for pulse wave simultaneous acquisition at multiple locations in a region of the human body.
  • the second aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention uses a respiratory wave acquisition device to acquire a synchronized respiratory wave of a person to be tested.
  • the pulse wave sensor performs pulse wave acquisition while using a non-contact type. Synchronous acquisition of respiratory waves by sensors such as Pule radar or respiratory chest straps that acquire respiratory waves based on thoracic displacement, or chest impedance based on impedance method
  • the sensor that acquires the respiratory wave is used for synchronous acquisition of the respiratory wave, and the other method is used for synchronous acquisition of the respiratory wave; the other is to use the synchronous respiratory wave signal extractor to process the pulse wave data collected by the pulse wave sensor, and extract the breathing in the pulse wave signal.
  • the wave signal realizes the acquisition of the respiratory wave signal.
  • the third aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention is to analyze and process pulse wave and respiratory wave data by using a processing device, and to perform processing such as filtering and denoising the pulse wave signal and the respiratory wave signal, using Fourier transform.
  • Algorithms such as EMD extract time-domain and frequency-domain characteristic parameters of pulse waves and respiratory waves.
  • a fourth aspect of the pulse wave diagnosis system of the invention having respiratory wave acquisition is to use a diagnostic device to give a pulse wave diagnosis result with respiratory wave data, which is based on the analysis result of the pulse wave and the respiratory wave signal, according to the traditional Chinese medicine.
  • the pulse diagnosis theory gives pulse diagnosis information such as pulse potential, pulse length, intensity, and rhythm “every minute”.
  • FIG. 2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • step S101 information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
  • step S102 the pulse wave of the person to be tested is collected and the respiratory wave of the person to be tested is synchronously collected.
  • a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain area of the human body surface; while a pulse wave is collected, a non-contact Doppler radar or a respiratory chest is used. Synchronously collect the respiratory wave of the person to be tested, and store the synchronized pulse wave and respiratory wave data.
  • the pulse wave and respiratory wave data are processed in step S103.
  • the synchronous pulse wave and the respiratory wave signal collected in S102 are processed by filtering and denoising, and the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave are extracted by using algorithms such as Fourier transform and EMD.
  • FIG. 3 is a waveform diagram of a pulse wave and a respiratory wave interaction relationship obtained by a pulse wave diagnosis system having respiratory wave acquisition according to an embodiment of the present invention.
  • S201 is a pulse wave waveform
  • S202 is a pulse wave.
  • Synchronous respiratory wave waveform according to the pulse wave data processing result in S103, the time interval T 1 of the pulse wave data stabilization is selected; according to the result of the synchronous respiratory wave data processing in S103, the time interval T 2 of the respiratory wave data stabilization is selected; T 3 is a pulse wave stabilizing time T.
  • Pulse wave diagnosis information is derived from all the data in step S105. For example, the information of the personal information of the person to be tested and the date and time of collection recorded in S101, and the data processing results of the pulse wave and the respiratory wave in S103, and the pulse wave number information between the information obtained in S104, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
  • FIG. 4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
  • step S301 information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
  • the pulse wave of the person to be tested is collected in step S302.
  • a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain region of the human body surface, and store pulse wave data.
  • the pulse wave is subjected to data processing and a respiratory wave is extracted in step S303.
  • a respiratory wave is extracted from the pulse wave using an algorithm such as Fourier transform or EMD.
  • EMD Fourier transform
  • the pulse wave and the extracted respiratory wave are further processed to acquire the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave.
  • step S304 a pulse wave and a respiratory wave interaction relationship such as "a few moments" are obtained.
  • S201 is the acquired pulse wave waveform
  • S202 is a respiratory wave waveform extracted from the pulse wave after data processing on the pulse wave, and pulse wave is selected according to the pulse wave data processing result in S303.
  • T 3 is the pulse wave stabilization time T 1 and the respiratory wave stabilization time period T 2 overlapping portions; data further processed to obtain the time interval T the pulse beats. 3 N 1, and the time interval T the number of breaths. 3 N 2; information can be obtained between the pulse wave to a number of N 1 / N 2 .
  • other respiratory waves and pulse waves can be derived.
  • Pulse wave diagnosis information is derived from all the data in step S305. For example, the information of the personal information of the person to be tested recorded in S301 and the date and time of collection, and the data processing results of the pulse wave and the respiratory wave in S303, and the pulse wave number information between the information obtained in S304, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
  • the pulse wave diagnosis system having the respiratory wave acquisition of the present invention and a method of using the same for diagnosis have been fully described.
  • the system can restore the traditional diagnosis mode and obtain more comprehensive physiological information as the basis for pulse wave diagnosis. It not only provides the possibility of accurate diagnosis of pulse wave, but also provides in-depth study of pulse wave. A new idea.

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Abstract

A pulse wave diagnostic system having respiratory wave collection function, comprising a pulse wave sensor, a respiratory wave acquisition device, a processing device and a diagnostic device. The pulse wave sensor is used to collect the pulse wave of a person to be detected; the respiratory wave acquisition device is used to acquire the respiratory wave of the person to be detected that is synchronous with the pulse wave; the processing device is used to extract time-domain and frequency-domain characteristic parameters of the pulse wave and the respiratory wave; and the diagnostic device is used to obtain a diagnostic result of the pulse condition on the basis of the characteristic parameters. The diagnostic system can give a correlation between the respiratory wave and pulse wave such as "several beats in one respiratory cycle" and the like by processing the obtained respiratory wave and the pulse wave signals, such that the extraction of pulse-related physiological information is more comprehensive, which provides new possibilities for the studies of the pulse wave, especially of the relationship between the pulse wave and the cardiopulmonary function.

Description

一种兼具呼吸波采集的脉搏波诊断系统Pulse wave diagnosis system with respiratory wave acquisition 技术领域Technical field
本发明涉及一种脉搏波诊断系统,特别是涉及一种兼具呼吸波采集的脉搏波诊断系统。The present invention relates to a pulse wave diagnostic system, and more particularly to a pulse wave diagnostic system that combines respiratory wave acquisition.
背景技术Background technique
脉搏波是由心脏的周期性搏动沿动脉血管和血流向外周传播形成的。脉搏波的传播过程不仅受心脏本身,还受到沿途动脉和周围组织器官状况的影响,蕴含着丰富的人体生理和病理信息。随着脉搏波无创检测技术的发展,脉搏波的研究受到了中外医学界的重视。The pulse wave is formed by the periodic pulsation of the heart along the arterial blood vessels and blood flow to the periphery. The process of pulse wave propagation is not only affected by the heart itself, but also by the condition of the arteries and surrounding tissues and organs along the way, and contains abundant physiological and pathological information of the human body. With the development of pulse wave non-invasive detection technology, the study of pulse wave has attracted the attention of Chinese and foreign medical circles.
传统的中医诊脉,在通过把脉获取脉象信息的同时,把“一息之间脉几至”作为脉搏波搏动快慢的诊断标准,有“一息四到五至,三至则迟,六至则数”之说。其中“一息”即为一呼一吸。可见,呼吸波的采集对中医脉象诊断具有重要的临床意义。但目前的脉搏波诊断系统,一般只是通过传感器采集脉搏波,根据脉搏波的幅值与时值特征,提取时域或频域特征参数进行分析研究,并没有包含呼吸波信息。这样的脉诊系统不能重现传统脉诊“一息几至”的脉诊依据,不利于对脉象的准确诊断,在一定程度上阻碍了对脉搏波全面深入的研究。The traditional Chinese medicine diagnosis pulse, while obtaining the pulse information through the pulse, uses the pulse between the breath and the pulse as the diagnostic criteria for the pulse wave pulsation. There are "four to five to three, three to late, six to the number". Said. One of them is a breath. It can be seen that the collection of respiratory waves has important clinical significance for the diagnosis of pulse of traditional Chinese medicine. However, the current pulse wave diagnosis system generally only collects pulse waves through sensors, and extracts time domain or frequency domain characteristic parameters according to the amplitude and time characteristics of the pulse wave, and does not include respiratory wave information. Such a pulse diagnosis system can not reproduce the pulse diagnosis basis of the traditional pulse diagnosis, which is not conducive to the accurate diagnosis of the pulse, and to a certain extent hinders the comprehensive and in-depth study of the pulse wave.
发明内容Summary of the invention
本发明的目的在于提供了一种脉搏波诊断系统,特别是通过呼吸波信息的获取提供了一种更全面的脉搏波诊断系统。It is an object of the present invention to provide a pulse wave diagnostic system, and in particular to provide a more comprehensive pulse wave diagnostic system by acquiring respiratory wave information.
为了解决上述技术问题,本发明是通过以下技术方案实现的:In order to solve the above technical problems, the present invention is achieved by the following technical solutions:
一种兼具呼吸波采集的脉搏波诊断系统,包括脉搏波传感器、呼吸波获取装置、处理装置和诊断装置,其中,所述脉搏波传感器用于采集待测人员的脉搏波;所述呼吸波获取装置用于获取待测人员的与其脉搏 波同步的呼吸波;所述处理装置用于提取所述脉搏波和呼吸波的时域和频域特征参数;所述诊断装置用于根据所述特征参数获取脉象诊断结果。A pulse wave diagnosis system having respiratory wave acquisition, comprising a pulse wave sensor, a respiratory wave acquiring device, a processing device, and a diagnostic device, wherein the pulse wave sensor is configured to collect a pulse wave of a person to be tested; The acquisition device is used to obtain the pulse of the person to be tested Wave-synchronized respiratory wave; the processing device is configured to extract time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave; the diagnostic device is configured to obtain a pulse diagnosis result according to the characteristic parameter.
所述脉搏波传感器是在一定时间内,在人体外周某一区域的单个位置进行脉搏波采集的脉搏波传感器。或者,所述脉搏波传感器是在一定时间内,在人体外周某一区域的多个位置进行脉搏波同步采集的阵列式脉搏波传感器,包括压力传感器、在人体体表某一区域进行无创多点脉搏波同步采集的多路阵列式脉搏波传感器等。The pulse wave sensor is a pulse wave sensor that performs pulse wave acquisition at a single position in a certain area of the human body outside a certain period of time. Alternatively, the pulse wave sensor is an array type pulse wave sensor that performs pulse wave synchronous acquisition at a plurality of positions in a certain area of the human body outside a certain period of time, including a pressure sensor, and performs non-invasive multi-point on a certain area of the human body surface. A multi-array pulse wave sensor for synchronous acquisition of pulse waves.
所述呼吸波获取装置是在采集待测人员脉搏波的同时进行呼吸波同步采集的传感器。所述呼吸波获取置是使用非接触式多普勒雷达或呼吸胸带等基于胸腔位移获取呼吸波的传感器,或者是使用基于阻抗法进行朐阻抗测量获取呼吸波的传感器。另外,所述呼吸波获取装置也可以是从脉搏信号中提取同步呼吸波信号的提取器,使用傅里叶变换或EMD算法等相关算法从脉搏波中提取呼吸波信号。The respiratory wave acquiring device is a sensor that performs synchronous acquisition of respiratory waves while acquiring a pulse wave of a person to be tested. The respiratory wave acquisition device is a sensor that acquires a respiratory wave based on a chest displacement using a non-contact Doppler radar or a respiratory chest strap, or a sensor that acquires a respiratory wave using a impedance method based on a sputum impedance measurement. In addition, the respiratory wave acquiring device may be an extractor that extracts a synchronized respiratory wave signal from a pulse signal, and extracts a respiratory wave signal from the pulse wave using a correlation algorithm such as Fourier transform or EMD algorithm.
所述处理装置使用傅里叶变换或EMD算法等相关算法提取所述脉搏波和呼吸波的时域和频域特征参数。The processing device extracts time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave using a correlation algorithm such as a Fourier transform or an EMD algorithm.
所述诊断装置是能给出节律“一息几至”及其他与呼吸相关的脉象诊断信息的装置。The diagnostic device is a device that can give rhythm "on the fly" and other respiratory related pulse diagnostic information.
本发明通过引入了呼吸波采集具有以下有益效果:The present invention has the following beneficial effects by introducing respiratory wave acquisition:
1、使与脉诊相关的生理信息提取更为全面;1. Make the extraction of physiological information related to pulse diagnosis more comprehensive;
2、使脉搏波方法的诊断过程更符合传统中医脉诊学精粹;2. Make the diagnosis process of the pulse wave method more in line with the essence of traditional Chinese medicine pulse diagnosis;
3、为脉搏波研究尤其是脉搏波与心肺功能关系的研究提供了新的可能。3. It provides new possibilities for the study of pulse wave research, especially the relationship between pulse wave and cardiopulmonary function.
附图说明DRAWINGS
图1是根据本发明的一种兼具呼吸波采集的脉搏波诊断系统结构图;1 is a structural diagram of a pulse wave diagnostic system having respiratory wave acquisition according to the present invention;
图2是本发明的兼具呼吸波采集的脉搏波诊断系统的一个实施例的流程图;2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention;
图3是根据本发明的一个实施例的兼具呼吸波采集的脉搏波诊断系 统所获得的脉搏波及呼吸波交互关系波形图;3 is a pulse wave diagnostic system that combines respiratory wave acquisition in accordance with an embodiment of the present invention. Waveforms of pulse wave and respiratory wave interaction obtained by the system;
图4是本发明的兼具呼吸波采集的脉搏波诊断系统的另一实施例的流程图。4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
具体实施方式detailed description
为使本发明的目的、技术方案和优点更加清楚明白,以下结合具体实施例,并参照附图,对本发明作进一步的详细说明。下面的介绍是本发明的多个可能实施例中的一些,目的在于促进对本发明的基本了解,并不在于确定本发明中的关键要素或限定所要保护的范围。容易理解,根据本发明的技术方案,在不改变本发明的实质的条件下,本领域的技术人员可以提出可替换的其它实现方式。因此,以下具体实施方式及附图仅是对本发明的技术方案的示例性说明,而不应当视为本发明的全部内容或者本发明技术方案的限制范围。The present invention will be further described in detail below with reference to the specific embodiments of the invention, The following description is of some of the many possible embodiments of the present invention, and is intended to provide a basic understanding of the invention and is not intended to be It will be readily understood that those skilled in the art can suggest alternative implementations in accordance with the teachings of the present invention without departing from the spirit of the invention. Therefore, the following detailed description and the accompanying drawings are merely illustrative of the embodiments of the invention, and are not intended to
本发明实现路径如下:The implementation path of the present invention is as follows:
(1)使用传感器采集待测人员脉搏波;(1) Using a sensor to collect a pulse wave of a person to be tested;
(2)获取待测人员同步呼吸波;(2) Obtaining synchronized breathing waves of the person to be tested;
(3)分析处理脉搏波及呼吸波数据;(3) analyzing and processing pulse wave and respiratory wave data;
(4)给出具有呼吸波数据的脉搏波诊断结果。(4) A pulse wave diagnosis result having respiratory wave data is given.
如图1所示,本发明的一种兼具呼吸波采集的脉搏波诊断系统结构图。As shown in FIG. 1, a structural diagram of a pulse wave diagnosis system having respiratory wave acquisition according to the present invention.
所述发明的一种兼具呼吸波采集的脉搏波诊断系统第一个方面使用脉搏波传感器采集待测人员脉搏波,是在一定时间内,利用脉搏波传感器在人体外周某一区域单个位置进行脉搏波采集,或利用阵列式脉搏波传感器在人体外周某一区域的多个位置进行脉搏波同步采集。The first aspect of the invention relates to a pulse wave diagnosis system with respiratory wave acquisition. The pulse wave sensor is used to collect the pulse wave of the person to be tested, and the pulse wave sensor is used to perform a single position in a certain area of the human body outside the body within a certain period of time. Pulse wave acquisition, or the use of an array pulse wave sensor for pulse wave simultaneous acquisition at multiple locations in a region of the human body.
本发明的兼具呼吸波采集的脉搏波诊断系统第二个方面使用呼吸波获取装置获取待测人员同步呼吸波,一种情况是在脉搏波传感器进行脉搏波采集的同时,使用非接触式多普勒雷达或呼吸胸带等基于胸腔位移获取呼吸波的传感器进行呼吸波同步采集,或基于阻抗法进行胸阻抗 测量获取呼吸波的传感器进行呼吸波同步采集,及其他方式进行呼吸波同步采集;另一种情况是使用同步呼吸波信号提取器处理脉搏波传感器采集的脉搏波数据,提取脉搏波信号中的呼吸波信号,实现呼吸波信号的获取。The second aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention uses a respiratory wave acquisition device to acquire a synchronized respiratory wave of a person to be tested. One case is that the pulse wave sensor performs pulse wave acquisition while using a non-contact type. Synchronous acquisition of respiratory waves by sensors such as Pule radar or respiratory chest straps that acquire respiratory waves based on thoracic displacement, or chest impedance based on impedance method The sensor that acquires the respiratory wave is used for synchronous acquisition of the respiratory wave, and the other method is used for synchronous acquisition of the respiratory wave; the other is to use the synchronous respiratory wave signal extractor to process the pulse wave data collected by the pulse wave sensor, and extract the breathing in the pulse wave signal. The wave signal realizes the acquisition of the respiratory wave signal.
本发明的兼具呼吸波采集的脉搏波诊断系统第三个方面是使用处理装置分析处理脉搏波及呼吸波数据,是对脉搏波信号和呼吸波信号进行滤波去噪等处理,使用傅里叶变换、EMD等算法,提取脉搏波和呼吸波的时域和频域特征参数。The third aspect of the pulse wave diagnosis system with respiratory wave acquisition of the present invention is to analyze and process pulse wave and respiratory wave data by using a processing device, and to perform processing such as filtering and denoising the pulse wave signal and the respiratory wave signal, using Fourier transform. Algorithms such as EMD extract time-domain and frequency-domain characteristic parameters of pulse waves and respiratory waves.
所述发明的一种兼具呼吸波采集的脉搏波诊断系统第四个方面是使用诊断装置给出具有呼吸波数据的脉搏波诊断结果,是根据脉搏波及呼吸波信号的分析结果,依据传统中医脉诊理论,给出脉势、脉长、强度、节律“一息几至”等脉象诊断信息。A fourth aspect of the pulse wave diagnosis system of the invention having respiratory wave acquisition is to use a diagnostic device to give a pulse wave diagnosis result with respiratory wave data, which is based on the analysis result of the pulse wave and the respiratory wave signal, according to the traditional Chinese medicine. The pulse diagnosis theory gives pulse diagnosis information such as pulse potential, pulse length, intensity, and rhythm “every minute”.
图2是本发明的兼具呼吸波采集的脉搏波诊断系统的一个实施例的流程图。2 is a flow chart of one embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
在步骤S101中登记待测人员个人信息及采集日期时间等信息。例如:登记待测人员年龄、身高、体重、病史等个人信息,以及登记进行采集脉搏波及呼吸波时的日期时间等。这是由于脉搏波的形态特征会随待测人员年龄、季节、时辰等因素变化,记录待测人员的个人信息以及采集时间日期等信息,有利于得出准确的脉搏波诊断结果。In step S101, information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
在步骤S102中采集待测人员脉搏波并同步采集待测人员呼吸波。例如:使用由压力传感器构成的多路阵列式脉搏波传感器,在人体体表某一区域进行无创多点脉搏波同步采集;在脉搏波采集的同时,使用非接触式多普勒雷达或呼吸胸带等同步采集待测人员呼吸波,存储同步的脉搏波及呼吸波数据。In step S102, the pulse wave of the person to be tested is collected and the respiratory wave of the person to be tested is synchronously collected. For example, a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain area of the human body surface; while a pulse wave is collected, a non-contact Doppler radar or a respiratory chest is used. Synchronously collect the respiratory wave of the person to be tested, and store the synchronized pulse wave and respiratory wave data.
在步骤S103中对脉搏波及呼吸波数据进行处理。例如:对S102中采集的同步脉搏波和呼吸波信号进行滤波去噪等处理,使用傅里叶变换、EMD等算法,提取脉搏波和呼吸波的时域和频域特征参数。The pulse wave and respiratory wave data are processed in step S103. For example, the synchronous pulse wave and the respiratory wave signal collected in S102 are processed by filtering and denoising, and the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave are extracted by using algorithms such as Fourier transform and EMD.
在步骤S104中得出“一息几至”等脉搏波及呼吸波交互关系。例如图3根据本发明的一个实施例的兼具呼吸波采集的脉搏波诊断系统所 获得的脉搏波及呼吸波交互关系波形图,如图3所示,S201是脉搏波波形,S202是与脉搏波同步的呼吸波波形;根据在S103中的脉搏波数据处理结果,选取脉搏波数据稳定的时间区间T1;根据S103中同步呼吸波数据处理的结果,选取呼吸波数据稳定的时间区间T2;T3为脉搏波稳定时间T1与呼吸波稳定时间T2的时间重合部分;进一步对数据进行处理,得T3时间区间内脉搏跳动次数N1,与T3时间区间内呼吸次数N2;则可得一息之间脉搏波至数为N1/N2。除一息之间至数信息外,也可得出呼吸波与脉搏波的其他相互关系。In step S104, a pulse wave and a respiratory wave interaction relationship such as "a few moments" are obtained. For example, FIG. 3 is a waveform diagram of a pulse wave and a respiratory wave interaction relationship obtained by a pulse wave diagnosis system having respiratory wave acquisition according to an embodiment of the present invention. As shown in FIG. 3, S201 is a pulse wave waveform, and S202 is a pulse wave. Synchronous respiratory wave waveform; according to the pulse wave data processing result in S103, the time interval T 1 of the pulse wave data stabilization is selected; according to the result of the synchronous respiratory wave data processing in S103, the time interval T 2 of the respiratory wave data stabilization is selected; T 3 is a pulse wave stabilizing time T. 1 coincide with the respiratory wave stabilizing time T 2 time portion; further data is processed to obtain the pulse beat within T. 3 time interval the number N 1, and the T. 3 time interval the number of breaths N 2; Then, the pulse wave number between the two is N 1 /N 2 . In addition to the information between the breaks, other correlations between the respiratory wave and the pulse wave can be derived.
在步骤S105中根据所有数据得出脉搏波诊断信息。例如:综合S101中记录的待测人员个人信息及采集日期时间等信息,及S103中脉搏波和呼吸波的数据处理结果,及S104中获得的一息之间脉搏波至数信息,以传统中医脉诊理论为依据,得出脉象诊断结果。Pulse wave diagnosis information is derived from all the data in step S105. For example, the information of the personal information of the person to be tested and the date and time of collection recorded in S101, and the data processing results of the pulse wave and the respiratory wave in S103, and the pulse wave number information between the information obtained in S104, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
图4是本发明的兼具呼吸波采集的脉搏波诊断系统的另一实施例的流程图。4 is a flow chart of another embodiment of a pulse wave diagnostic system having respiratory wave acquisition of the present invention.
在步骤S301中登记待测人员个人信息及采集日期时间等信息。例如:登记待测人员年龄、身高、体重、病史等个人信息,以及登记进行采集脉搏波及呼吸波时的日期时间等。这是由于脉搏波的形态特征会随待测人员年龄、季节、时辰等因素变化,记录待测人员的个人信息以及采集时间日期等信息,有利于得出准确的脉搏波诊断结果。In step S301, information such as personal information of the person to be tested and date and time of collection are registered. For example, register the personal information such as the age, height, weight, and medical history of the person to be tested, and register the date and time when collecting the pulse wave and the respiratory wave. This is because the morphological characteristics of the pulse wave will change with the age, season, and time of the person to be tested. Recording the personal information of the person to be tested and the time and date of the acquisition will help to obtain accurate pulse wave diagnosis results.
在步骤S302中采集待测人员脉搏波。例如:使用由压力传感器构成的多路阵列式脉搏波传感器,在人体体表某一区域进行无创多点脉搏波同步采集,存储脉搏波数据。The pulse wave of the person to be tested is collected in step S302. For example, a multi-channel array pulse wave sensor composed of a pressure sensor is used to perform non-invasive multi-point pulse wave synchronous acquisition in a certain region of the human body surface, and store pulse wave data.
在步骤S303中对脉搏波进行数据处理并提取呼吸波。例如:对S302中采集的脉搏波进行去噪等处理,使用傅里叶变换、EMD等算法,从脉搏波中提取呼吸波。在此基础上,对脉搏波和提取出的呼吸波进一步进行处理,获取脉搏波和呼吸波的时域和频域特征参数。The pulse wave is subjected to data processing and a respiratory wave is extracted in step S303. For example, the pulse wave collected in S302 is denoised and processed, and a respiratory wave is extracted from the pulse wave using an algorithm such as Fourier transform or EMD. On this basis, the pulse wave and the extracted respiratory wave are further processed to acquire the time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave.
在步骤S304中得出“一息几至”等脉搏波及呼吸波交互关系。例如:如图3所示,S201为采集的脉搏波波形,S202为对脉搏波进行数据处理后,从脉搏波中提取的呼吸波波形;根据在S303中的脉搏波数 据处理结果,选取脉搏波数据稳定的时间区间T1;根据S303中从脉搏波提取出的呼吸波数据处理的结果,选取呼吸波数据稳定,波形良好的时间区间T2;T3为脉搏波稳定时间T1与呼吸波稳定时间T2的时间重合部分;进一步对数据进行处理,得T3时间区间内脉搏跳动次数N1,与T3时间区间内呼吸次数N2;则可得一息之间脉搏波至数为N1/N2。除一息之间至数信息外,也可得出其他呼吸波与脉搏波相互关系。In step S304, a pulse wave and a respiratory wave interaction relationship such as "a few moments" are obtained. For example, as shown in FIG. 3, S201 is the acquired pulse wave waveform, S202 is a respiratory wave waveform extracted from the pulse wave after data processing on the pulse wave, and pulse wave is selected according to the pulse wave data processing result in S303. The time interval T 1 of data stabilization; according to the result of the processing of the respiratory wave data extracted from the pulse wave in S303, the time interval T 2 in which the respiratory wave data is stable and the waveform is good is selected; T 3 is the pulse wave stabilization time T 1 and the respiratory wave stabilization time period T 2 overlapping portions; data further processed to obtain the time interval T the pulse beats. 3 N 1, and the time interval T the number of breaths. 3 N 2; information can be obtained between the pulse wave to a number of N 1 / N 2 . In addition to the information between the breaks, other respiratory waves and pulse waves can be derived.
在步骤S305中根据所有数据得出脉搏波诊断信息。例如:综合S301中记录的待测人员个人信息及采集日期时间等信息,及S303中脉搏波和呼吸波的数据处理结果,及S304中获得的一息之间脉搏波至数信息,以传统中医脉诊理论为依据,得出脉象诊断结果。Pulse wave diagnosis information is derived from all the data in step S305. For example, the information of the personal information of the person to be tested recorded in S301 and the date and time of collection, and the data processing results of the pulse wave and the respiratory wave in S303, and the pulse wave number information between the information obtained in S304, in the traditional Chinese medicine pulse Based on the diagnosis theory, the pulse diagnosis results are obtained.
至此,已全面说明了本发明的兼具呼吸波采集的脉搏波诊断系统及使用其进行诊断的方法。该系统通过呼吸波信息的引入,最大可能的还原了传统诊脉方式,获取了更为全面的生理信息作为脉搏波诊断依据,不仅为脉搏波准确诊断提供了可能,也为脉搏波的深入研究提供了新的思路。Heretofore, the pulse wave diagnosis system having the respiratory wave acquisition of the present invention and a method of using the same for diagnosis have been fully described. Through the introduction of respiratory wave information, the system can restore the traditional diagnosis mode and obtain more comprehensive physiological information as the basis for pulse wave diagnosis. It not only provides the possibility of accurate diagnosis of pulse wave, but also provides in-depth study of pulse wave. A new idea.
以上所述的具体实施例,对本发明的目的、技术方案和有益效果进行了进一步详细说明,应理解的是,以上所述仅为本发明的具体实施例而已,并不用于限制本发明,凡在本发明的精神和原则之内,所做的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。 The specific embodiments of the present invention have been described in detail in the foregoing detailed description of the embodiments of the present invention. All modifications, equivalents, improvements, etc., made within the spirit and scope of the invention are intended to be included within the scope of the invention.

Claims (12)

  1. 一种兼具呼吸波采集的脉搏波诊断系统,其中,包括脉搏波传感器、呼吸波获取装置、处理装置和诊断装置,其中,A pulse wave diagnosis system having a respiratory wave acquisition, which includes a pulse wave sensor, a respiratory wave acquisition device, a processing device, and a diagnostic device, wherein
    所述脉搏波传感器用于采集待测人员的脉搏波;The pulse wave sensor is configured to collect a pulse wave of a person to be tested;
    所述呼吸波获取装置用于获取待测人员的与其脉搏波同步的呼吸波;The respiratory wave acquiring device is configured to acquire a respiratory wave of a person to be tested synchronized with a pulse wave thereof;
    所述处理装置用于提取所述脉搏波和呼吸波的时域和频域特征参数;The processing device is configured to extract time domain and frequency domain characteristic parameters of the pulse wave and the respiratory wave;
    所述诊断装置用于根据所述特征参数获取脉象诊断结果。The diagnostic device is configured to obtain a pulse diagnosis result according to the characteristic parameter.
  2. 根据权利要求1所述的脉搏波诊断系统,其中,所述呼吸波获取装置是在采集待测人员脉搏波的同时进行呼吸波同步采集的传感器。The pulse wave diagnosis system according to claim 1, wherein said respiratory wave acquisition means is a sensor that performs synchronous acquisition of respiratory waves while acquiring a pulse wave of a person to be tested.
  3. 根据权利要求2所述的脉搏波诊断系统,其中,所述呼吸波获取置是使用非接触式多普勒雷达或呼吸胸带等基于胸腔位移获取呼吸波的传感器。The pulse wave diagnosis system according to claim 2, wherein the respiratory wave acquisition means is a sensor that acquires a respiratory wave based on a chest displacement using a non-contact Doppler radar or a respiratory chest strap.
  4. 根据权利要求2所述的脉搏波诊断系统,其中,所述呼吸波获取装置是使用基于阻抗法进行胸阻抗测量获取呼吸波的传感器。The pulse wave diagnosis system according to claim 2, wherein the respiratory wave acquisition means is a sensor that acquires a respiratory wave using a thoracic impedance measurement based on an impedance method.
  5. 根据权利要求1所述的脉搏波诊断系统,其中,所述呼吸波获取装置是从脉搏信号中提取同步呼吸波信号的提取器。The pulse wave diagnostic system according to claim 1, wherein said respiratory wave acquiring means is an extractor that extracts a synchronized respiratory wave signal from a pulse signal.
  6. 根据权利要求5所述的脉搏波诊断系统,其中,所述呼吸波获取装置是使用傅里叶变换或EMD算法从脉搏波中提取呼吸波信号的提取器。The pulse wave diagnostic system according to claim 5, wherein said respiratory wave acquiring means is an extractor that extracts a respiratory wave signal from a pulse wave using a Fourier transform or an EMD algorithm.
  7. 根据权利要求1至6中任意一项所述的脉搏波诊断系统,其中,所述处理装置使用傅里叶变换或EMD算法提取所述脉搏波和呼吸波的时域和频域特征参数。The pulse wave diagnostic system according to any one of claims 1 to 6, wherein the processing means extracts time-domain and frequency-domain characteristic parameters of the pulse wave and the respiratory wave using a Fourier transform or an EMD algorithm.
  8. 根据权利要求1至6中任意一项所述的脉搏波诊断系统,其中,所述诊断装置是能给出节律“一息几至”的脉象诊断信息的装置。The pulse wave diagnosis system according to any one of claims 1 to 6, wherein said diagnosis means is means for giving pulse diagnosis information of a rhythm "every minute".
  9. 根据权利要求1至6中任意一项所述的脉搏波诊断系统,其中,所述脉搏波传感器是在一定时间内,在人体外周某一区域的单个位置进 行脉搏波采集的脉搏波传感器。The pulse wave diagnostic system according to any one of claims 1 to 6, wherein the pulse wave sensor is in a single position in a certain area of the human body outside a certain period of time A pulse wave sensor for pulse wave acquisition.
  10. 根据权利要求1至6中任意一项所述的脉搏波诊断系统,其中,所述脉搏波传感器是在一定时间内,在人体外周某一区域的多个位置进行脉搏波同步采集的阵列式脉搏波传感器。The pulse wave diagnostic system according to any one of claims 1 to 6, wherein the pulse wave sensor is an array pulse that performs pulse wave synchronous acquisition at a plurality of positions in a certain region of the human body outside of a certain period of time. Wave sensor.
  11. 根据权利要求10所述的脉搏波诊断系统,其中,所述脉搏波传感器是压力传感器。The pulse wave diagnostic system according to claim 10, wherein said pulse wave sensor is a pressure sensor.
  12. 根据权利要求10所述的脉搏诊断系统,其中,所述脉搏波传感器是在人体体表某一区域进行无创多点脉搏波同步采集的多路阵列式脉搏波传感器。 The pulse diagnosis system according to claim 10, wherein said pulse wave sensor is a multi-channel array type pulse wave sensor that performs non-invasive multi-point pulse wave synchronous acquisition in a certain region of a body surface.
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CN106308769A (en) * 2016-09-07 2017-01-11 中国科学院微电子研究所 Pulse wave diagnosis system having respiratory wave acquisition function

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CN111084618A (en) * 2019-12-13 2020-05-01 安徽通灵仿生科技有限公司 Wearable multifunctional respiration cycle detection system and method
CN111449638A (en) * 2020-04-08 2020-07-28 上海祉云医疗科技有限公司 Method for constructing three-dimensional pulse picture based on data acquired by sensor and application
CN114722855A (en) * 2022-02-28 2022-07-08 太原理工大学 Identification processing method of slippery pulse wave

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