WO2017214866A1 - Reagent kit having cooling function, alarm function, and wireless management function - Google Patents

Reagent kit having cooling function, alarm function, and wireless management function Download PDF

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Publication number
WO2017214866A1
WO2017214866A1 PCT/CN2016/085768 CN2016085768W WO2017214866A1 WO 2017214866 A1 WO2017214866 A1 WO 2017214866A1 CN 2016085768 W CN2016085768 W CN 2016085768W WO 2017214866 A1 WO2017214866 A1 WO 2017214866A1
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Prior art keywords
function
reagent
kit
management
reagent kit
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PCT/CN2016/085768
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French (fr)
Chinese (zh)
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彭鹏
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彭鹏
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Priority to PCT/CN2016/085768 priority Critical patent/WO2017214866A1/en
Publication of WO2017214866A1 publication Critical patent/WO2017214866A1/en

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Definitions

  • the present invention relates to the field of biotechnology, and in particular to a kit having a cold retention function, an alarm function, and a wireless management function.
  • kits In the field of biotechnology, in addition to technical breakthroughs, it is more important to improve the efficiency of research and experimentation. Among them, the emergence of kits plays an important role.
  • the kit standardizes the steps of common biological experiments, providing the experimenter with the reagents to be prepared and the optimized loading method, which greatly increases the speed of the experimental development and the degree of standardization of the results.
  • the present invention provides a kit having a cold keeping function, an alarm function, and a wireless management function.
  • the technical solution adopted by the present invention is: a kit having a cold keeping function, an alarm function and a wireless management function, comprising a kit body, wherein the reagent box body is provided with a plurality of reagent holes, a sounding device and a control unit a small battery and a short-range wireless communication NFC tag, wherein the sounding device, the control unit and the battery are electrically connected; the outer wall of the reagent hole is provided with a refrigeration device and a temperature control probe, and the refrigeration device, the temperature control probe and the control unit Electrical connection between the short-range wireless communication NFC tag and the control unit.
  • the NFC tag of the short-range wireless communication is composed of a data storage module and a data transmission module. The output end of the data storage module is electrically connected to the data transmission module, and the data transmission module wirelessly transmits the signal to the intelligent management terminal used by the staff through the NFC chip.
  • kit body has a two-layer structure, and the control unit, the sounding device and the small power storage battery are disposed between the inner layer and the outer layer of the reagent cartridge body.
  • the present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment. With the intelligent management terminal and the kit, the non-contact point-to-point can be realized within a distance of five centimeters.
  • the data transmission solves many problems of the traditional kit production management method, improves the efficiency and accuracy of management, and reduces the management cost for the production enterprise. Brief description of the drawing
  • FIG. 3 is a schematic structural diagram of the short-range wireless communication NFC tag.
  • a kit having a cold storage function, an alarm function, and a wireless management function includes a kit body 10, and the reagent cartridge body is provided with a plurality of reagent holes 20, a sounding device 30, and a control unit. 4, a small battery (not shown) and a short-range wireless communication NFC tag 50, the sounding device, the control unit and the battery are electrically connected;
  • the wall of the reagent hole is provided with a refrigerating device 201 and a temperature control probe 202, and the refrigerating device, the temperature control probe and the control unit are electrically connected;
  • the short-range wireless communication NFC tag is composed of a data storage module 501 and a data transmission module 502.
  • the output end of the data storage module is electrically connected to the data transmission module, and the data transmission module passes through the NFC chip 503.
  • the signal is wirelessly transmitted to the intelligent management terminal 60 used by the worker.
  • the present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment. With the intelligent management terminal and the kit, the non-contact point-to-point can be realized within a distance of five centimeters.
  • the data transmission solves many problems of the traditional kit production management method, improves the efficiency and accuracy of management, and reduces the management cost for the production enterprise.
  • the present invention provides a sounding device, a control unit, a battery, and an outer wall of the reagent hole in the kit body.
  • the cooling device and the temperature control probe can provide the required pre-cooling environment (2-8 °C) for the reagent, and the temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alarms the experimenter to reduce the experimenter.
  • the probability of failure of the experiment; with the intelligent management terminal and the kit, the non-contact point-to-point data transmission can be realized within a distance of five centimeters, solving many problems of the traditional kit production management method, and improving the efficiency and accuracy of management. , reducing management costs for production companies.

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Abstract

A reagent kit having a cooling function, alarm function, and wireless management function. The reagent kit comprises a main body (10) provided with several reagent recesses (20), a sound generating device (30), a control unit (40), a small storage battery, and a near field communication (NFC) tag (50). By providing a sound generating device (30), a control unit (40), and a storage battery at a main body (10) of the reagent kit, and providing a refrigerating device (201) and a temperature control probe (202) at an external wall of a reagent recesses (20), the present invention provides a desired pre-cooling environment (2-8°C) for a reagent, and enables temperature detection by means of the temperature control probe (202). When the temperature exceeds a preset range, the sound generating device (30) immediately gives an alarm to notify lab personnel, thus reducing the probability of experiment failures. At the same time, by employing contactless end-to-end data transmission between an intelligent management terminal (60) and the reagent kit within a five-centimeter range, the present invention solves numerous problems of manufacturing management methods of conventional reagent kits, thus improving efficiency and precision of management, and reducing a management cost of the manufacturer.

Description

发明名称:一种具有保冷功能、 报警功能和无线管理功能的试剂盒 技术领域  Title of Invention: A kit with cold storage, alarm function and wireless management function
[0001] 本发明涉及生物技术领域, 特别是涉及一种具有保冷功能、 报警功能和无线管 理功能的试剂盒。  [0001] The present invention relates to the field of biotechnology, and in particular to a kit having a cold retention function, an alarm function, and a wireless management function.
背景技术  Background technique
[0002] 生物技术领域的发展, 除了技术上的突破外, 更重要的是通过研究和实验效率 的提高, 而这其中, 试剂盒的出现起到了很重要的作用。 试剂盒将常见的生物 学实验的步骤标准化, 为实验者提供将配制好的试剂和优化的加样方法, 大幅 提高了实验幵展的速度和结果的标准化程度。  [0002] In the field of biotechnology, in addition to technical breakthroughs, it is more important to improve the efficiency of research and experimentation. Among them, the emergence of kits plays an important role. The kit standardizes the steps of common biological experiments, providing the experimenter with the reagents to be prepared and the optimized loading method, which greatly increases the speed of the experimental development and the degree of standardization of the results.
技术问题  technical problem
[0003] 由于生物学的特性, 很多试剂在使用吋为保证试剂的有效性和实验的准确性, 需要在低温 (2-8°C) 环境下完成, 而目前, 此类操作通常是使用"冰盒"来完成 , 即将冰块加到大小合适的泡沫盒中, 然后将试剂管插到冰中, 确保试剂处于 所需的低温状态。 但由于很多生物学实验需要进行无菌操作, 而冰块很容易沾 上空气中的细菌, 是实验中细菌污染的一个潜在来源, 因此使用"冰盒"进行的低 温加样操作在做这些实验吋对实验人员的操作要求较高, 提高了实验人员的负 担, 并且实验成功率无法得到保证。 用"冰盒"的另一个缺点是, 无法确保插在其 中的试剂管是否为所需的温度环境 (2-8°C) 。 当温度超出这一范围, 实验人员 并无法立即得知这一情况, 可能也会对实验结果造成一定的影响。  [0003] Due to the biological characteristics, many reagents in the use of hydrazine to ensure the effectiveness of the reagents and the accuracy of the experiment, need to be completed in a low temperature (2-8 ° C) environment, and currently, such operations are usually used " The ice box is "completed, the ice cubes are added to the appropriate size of the foam box, and the reagent tube is inserted into the ice to ensure that the reagents are at the desired low temperature. However, because many biological experiments require aseptic processing, and ice cubes are easily stained with bacteria in the air, which is a potential source of bacterial contamination in experiments, low-temperature loading operations using "ice boxes" are used in these experiments.吋 The requirements for the operation of the experimenter are higher, the burden on the experimenter is increased, and the experimental success rate cannot be guaranteed. Another disadvantage of using an "ice box" is that it is not possible to ensure that the reagent tube inserted in it is in the desired temperature environment (2-8 ° C). When the temperature is outside this range, the experimenter is not immediately aware of the situation and may have a certain impact on the experimental results.
[0004] 并且随着生物学的发展以及生物学与其他联系紧密的学科交织形成交叉学科的 增多, 试剂盒的种类也在不断地增多。 对于试剂盒的生产厂家, 尤其是生产种 类繁多、 应用广泛的试剂盒的大型厂家来说, 对于所生产的试剂盒的管理一直 都是非常具有挑战性的工作。 目前, 大部分生产商使用的管理方法还是由工作 人员将试剂盒的相关信息记录在纸质文档中, 并于需要吋找出相关文档进行核 对。 这种通过人工记录和比对的管理模式导致了试剂盒管理的效率低下且出错 率高, 而每年因此产生的用于"纠错"的额外支出高达数百万乃至数千万元。 问题的解决方案 [0004] And with the development of biology and the interdisciplinary combination of biology and other closely related disciplines, the variety of kits is constantly increasing. For the manufacturers of kits, especially for large manufacturers that produce a wide variety of widely used kits, the management of the kits produced has always been a very challenging task. At present, most manufacturers use the management method to record the relevant information of the kit in the paper document, and find the relevant documents to check if necessary. This manual recording and comparison management mode results in inefficient and high error rates for kit management, and the additional expenditure for "correction" generated each year amounts to millions or even tens of millions. Problem solution
技术解决方案  Technical solution
[0005] 为了解决现有技术存在的上述问题, 本发明提供了一种具有保冷功能、 报警功 能和无线管理功能的试剂盒。  In order to solve the above problems in the prior art, the present invention provides a kit having a cold keeping function, an alarm function, and a wireless management function.
[0006] 本发明所采用的技术方案为: 一种具有保冷功能、 报警功能和无线管理功能的 试剂盒, 包括试剂盒本体, 所述试剂盒本体上设有若干试剂孔、 发声装置以及 控制单元、 小型蓄电池和近距离无线通讯 NFC标签, 所述发声装置、 控制单元及 蓄电池之间电连; 所述试剂孔外壁设有制冷装置和温控探头, 所述制冷装置、 温控探头与控制单元之间电连; 所述近距离无线通讯 NFC标签与控制单元之间电 连。 所述近距离无线通讯 NFC标签由数据储存模块和数据传输模块组成, 数据存 储模块的输出端与数据传输模块电连, 数据传输模块通过 NFC芯片将信号无线 传输至工作人员使用的智能管理终端。  [0006] The technical solution adopted by the present invention is: a kit having a cold keeping function, an alarm function and a wireless management function, comprising a kit body, wherein the reagent box body is provided with a plurality of reagent holes, a sounding device and a control unit a small battery and a short-range wireless communication NFC tag, wherein the sounding device, the control unit and the battery are electrically connected; the outer wall of the reagent hole is provided with a refrigeration device and a temperature control probe, and the refrigeration device, the temperature control probe and the control unit Electrical connection between the short-range wireless communication NFC tag and the control unit. The NFC tag of the short-range wireless communication is composed of a data storage module and a data transmission module. The output end of the data storage module is electrically connected to the data transmission module, and the data transmission module wirelessly transmits the signal to the intelligent management terminal used by the staff through the NFC chip.
[0007] 进一步地, 所述试剂盒本体为双层结构, 所述控制单元、 发声装置和小型蓄电 池设置在试剂盒本体内层与外层之间。  Further, the kit body has a two-layer structure, and the control unit, the sounding device and the small power storage battery are disposed between the inner layer and the outer layer of the reagent cartridge body.
[0008] 进— -步地  [0008] In-step
[0009] 进— -步地  [0009] In-step
[0010] 进— -步地  [0010] In-step
[0011] 进— -步地  [0011] In-step
[0012] 进— -步地  [0012] In-step
相关信息。  Related Information.
发明的有益效果  Advantageous effects of the invention
有益效果  Beneficial effect
[0013] 本发明通过在试剂盒本体设置发声装置、 控制单元及蓄电池和在试剂孔外壁设 置制冷装置和温控探头, 可为试剂提供所需的预冷环境 (2-8°C) , 并且可以通 过温控探头检测温度, 一旦超出设定范围, 发声装置立即报警提醒实验人员, 减少实验失败的机率; 同吋借助智能管理终端与试剂盒可在五厘米的距离内实 现非接触式点对点的数据传输, 解决了传统试剂盒生产管理方法的诸多问题, 提升了管理的效率和准确性, 为生产企业降低了管理成本。 对附图的简要说明 [0013] The present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment. With the intelligent management terminal and the kit, the non-contact point-to-point can be realized within a distance of five centimeters. The data transmission solves many problems of the traditional kit production management method, improves the efficiency and accuracy of management, and reduces the management cost for the production enterprise. Brief description of the drawing
附图说明  DRAWINGS
[0014] 图 1是本发明的整体结构图。 1 is an overall configuration diagram of the present invention.
[0015] 图 2是所述试剂孔的结构图。 2 is a structural view of the reagent well.
[0016] 图 3是所述近距离无线通讯 NFC标签的结构示意图。  3 is a schematic structural diagram of the short-range wireless communication NFC tag.
实施该发明的最佳实施例  BEST MODE FOR CARRYING OUT THE INVENTION
本发明的最佳实施方式  BEST MODE FOR CARRYING OUT THE INVENTION
[0017] 以下结合附图, 对本发明作进一步说明。 [0017] The present invention will be further described below in conjunction with the accompanying drawings.
[0018] 如图 1所示, 一种具有保冷功能、 报警功能和无线管理功能的试剂盒, 包括试 剂盒本体 10, 所述试剂盒本体上设有若干试剂孔 20、 发声装置 30以及控制单元 4 0、 小型蓄电池 (图中未显示) 和近距离无线通讯 NFC标签 50, 所述发声装置、 控制单元及蓄电池之间电连;  [0018] As shown in FIG. 1, a kit having a cold storage function, an alarm function, and a wireless management function includes a kit body 10, and the reagent cartridge body is provided with a plurality of reagent holes 20, a sounding device 30, and a control unit. 4, a small battery (not shown) and a short-range wireless communication NFC tag 50, the sounding device, the control unit and the battery are electrically connected;
[0019] 如图 2所示, 所述试剂孔的壁设有制冷装置 201和温控探头 202, 所述制冷装置 、 温控探头与控制单元之间电连;  [0019] As shown in FIG. 2, the wall of the reagent hole is provided with a refrigerating device 201 and a temperature control probe 202, and the refrigerating device, the temperature control probe and the control unit are electrically connected;
[0020] 如图 3所示, 所述近距离无线通讯 NFC标签由数据储存模块 501和数据传输模块 组成 502, 数据存储模块的输出端与数据传输模块电连, 数据传输模块通过 NFC 芯片 503将信号无线传输至工作人员使用的智能管理终端 60。  [0020] As shown in FIG. 3, the short-range wireless communication NFC tag is composed of a data storage module 501 and a data transmission module 502. The output end of the data storage module is electrically connected to the data transmission module, and the data transmission module passes through the NFC chip 503. The signal is wirelessly transmitted to the intelligent management terminal 60 used by the worker.
[0021] 本发明通过在试剂盒本体设置发声装置、 控制单元及蓄电池和在试剂孔外壁设 置制冷装置和温控探头, 可为试剂提供所需的预冷环境 (2-8°C) , 并且可以通 过温控探头检测温度, 一旦超出设定范围, 发声装置立即报警提醒实验人员, 减少实验失败的机率; 同吋借助智能管理终端与试剂盒可在五厘米的距离内实 现非接触式点对点的数据传输, 解决了传统试剂盒生产管理方法的诸多问题, 提升了管理的效率和准确性, 为生产企业降低了管理成本。  [0021] The present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment. With the intelligent management terminal and the kit, the non-contact point-to-point can be realized within a distance of five centimeters. The data transmission solves many problems of the traditional kit production management method, improves the efficiency and accuracy of management, and reduces the management cost for the production enterprise.
[0022] 本发明不局限于上述最佳实施方式, 任何人在本发明的启示下都可得出其他各 种形式的产品, 但不论在其形状或结构上作任何变化, 凡是具有与本申请相同 或相近似的技术方案, 均落在本发明的保护范围之内。  [0022] The present invention is not limited to the above-described preferred embodiments, and any other form of product can be derived by anyone of the present invention, but without any change in its shape or structure, The same or similar technical solutions are all within the scope of the present invention.
工业实用性  Industrial applicability
[0023] 本发明通过在试剂盒本体设置发声装置、 控制单元及蓄电池和在试剂孔外壁设 置制冷装置和温控探头, 可为试剂提供所需的预冷环境 (2-8°C) , 并且可以通 过温控探头检测温度, 一旦超出设定范围, 发声装置立即报警提醒实验人员, 减少实验失败的机率; 同吋借助智能管理终端与试剂盒可在五厘米的距离内实 现非接触式点对点的数据传输, 解决了传统试剂盒生产管理方法的诸多问题, 提升了管理的效率和准确性, 为生产企业降低了管理成本。 [0023] The present invention provides a sounding device, a control unit, a battery, and an outer wall of the reagent hole in the kit body. The cooling device and the temperature control probe can provide the required pre-cooling environment (2-8 °C) for the reagent, and the temperature can be detected by the temperature control probe. Once the setting range is exceeded, the sounding device immediately alarms the experimenter to reduce the experimenter. The probability of failure of the experiment; with the intelligent management terminal and the kit, the non-contact point-to-point data transmission can be realized within a distance of five centimeters, solving many problems of the traditional kit production management method, and improving the efficiency and accuracy of management. , reducing management costs for production companies.

Claims

权利要求书 claims
[权利要求 1] 一种具有保冷功能、 报警功能和无线管理功能的试剂盒, 其特征在于 包括试剂盒本体, 所述试剂盒本体上设有若干试剂孔、 发声装置以及 控制单元、 小型蓄电池和近距离无线通讯 NFC标签。 所述发声装置、 控制单元及蓄电池之间电连。 [Claim 1] A reagent kit with a cold preservation function, an alarm function and a wireless management function, characterized in that it includes a reagent kit body, and the reagent kit body is provided with a number of reagent holes, a sound device and a control unit, a small battery and Near Field Communication NFC tag. The sound-generating device, the control unit and the battery are electrically connected.
[权利要求 2] 根据权利要求 1所述的一种具有保冷功能、 报警功能和无线管理功能 的试剂盒, 其特征在于所述发声装置为蜂鸣器。 [Claim 2] A test kit with a cold preservation function, an alarm function and a wireless management function according to claim 1, characterized in that the sound-generating device is a buzzer.
[权利要求 3] 根据权利要求 1所述的一种具有保冷功能、 报警功能和无线管理功能 的试剂盒, 其特征在于所述试剂盒本体为双层结构, 所述控制单元[Claim 3] A test kit with cold preservation function, alarm function and wireless management function according to claim 1, characterized in that the test kit body has a double-layer structure, and the control unit
、 发声装置和小型蓄电池设置在试剂盒本体内层与外层之间。 , the sound-generating device and the small battery are arranged between the inner layer and the outer layer of the kit body.
[权利要求 4] 根据权利要求 1所述的一种具有保冷功能、 报警功能和无线管理功能 的试剂盒, 其特征在于所述近距离无线通讯 NFC标签主要是由数据存 储模块、 数据传输模块和 NFC芯片组成。 [Claim 4] A kit with cold storage function, alarm function and wireless management function according to claim 1, characterized in that the short-range wireless communication NFC tag mainly consists of a data storage module, a data transmission module and a Composed of NFC chip.
[权利要求 5] 根据权利要求 1所述的一种具有保冷功能、 报警功能和无线管理功能 的试剂盒, 其特征在于所述数据存储模块与所述数据传输模块电连, 所述数据传输模块与所述 NFC芯片电连并通过无线信号将试剂盒的相 关数据发送到所述智能管理终端上。 [Claim 5] A test kit with cold preservation function, alarm function and wireless management function according to claim 1, characterized in that the data storage module is electrically connected to the data transmission module, and the data transmission module It is electrically connected to the NFC chip and sends relevant data of the test kit to the intelligent management terminal through wireless signals.
PCT/CN2016/085768 2016-06-15 2016-06-15 Reagent kit having cooling function, alarm function, and wireless management function WO2017214866A1 (en)

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