WO2017206017A1 - 快速修复烧烫伤创面的软膏剂 - Google Patents

快速修复烧烫伤创面的软膏剂 Download PDF

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WO2017206017A1
WO2017206017A1 PCT/CN2016/083897 CN2016083897W WO2017206017A1 WO 2017206017 A1 WO2017206017 A1 WO 2017206017A1 CN 2016083897 W CN2016083897 W CN 2016083897W WO 2017206017 A1 WO2017206017 A1 WO 2017206017A1
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ointment
parts
extract
burn wounds
weight
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吴克
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江苏奇力康皮肤药业有限公司
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Priority to CN201680000513.XA priority Critical patent/CN108348464A/zh
Priority to PCT/CN2016/083897 priority patent/WO2017206017A1/zh
Publication of WO2017206017A1 publication Critical patent/WO2017206017A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • the invention relates to a burn wound repairing agent, in particular to an ointment for quickly repairing burn wounds.
  • the currently available ointments for treating burns and scalds generally contain some hormonal ingredients. Although some of the more potent ingredients are used, although the speed of healing can be accelerated, it also brings some side effects. When the skin is burned or burned, it should be treated promptly, otherwise it will greatly delay the speed of skin recovery, and even cause the effects of staying.
  • the object of the present invention is to provide an ointment for quickly repairing burn wounds, which can effectively repair and repair skin burns below moderate to moderate, and has no irritation or side effects on human skin. .
  • An ointment for quickly repairing burn wounds comprising:
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of mantle extract.
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of a white peony extract.
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of catechu extract.
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of honeysuckle extract.
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of atractylodes extract.
  • the ointment for rapidly repairing burn wounds comprises 0.1-0.2 parts by weight of a white peony extract.
  • the invention has the beneficial effects that the present invention improves and optimizes the formula of the conventional burnt ointment product, and introduces the skin repairing traditional Chinese medicine ingredients such as the extract of the grass, the extract of the wintergreen skin and the extract of the comfrey, which effectively improves the pair. It burns and burns the skin's self-recovery function, and the optimized formula is mild and non-irritating to the human body, with no side effects, suitable for infants and young children.
  • the present invention provides an embodiment of an ointment for rapidly repairing burn wounds, which comprises:
  • Chinese herbal extracts here, such as extracts of green grass, winter rind extract, comfrey extract, etc. Refers to the solid matter obtained by extracting the corresponding Chinese medicine after solvent extraction and then removing the extraction solvent.
  • Atractylodes extract it is also preferred to include 0.1 to 0.2 parts by weight of atractylodes extract.
  • the extract of mantle extract, white peony root extract, catechu extract, honeysuckle extract, atractylodes extract and white peony extract are combined with extracts of green grass, winter rind extract and comfrey extract as a whole. They can produce synergistic effects and synergistically improve the repair function of the ointment on the affected area.
  • the somatosensory test when the ointment applied in the case was applied to the affected area for a long time, the pain was significantly decreased. After 2 days, the pain almost disappeared, and the redness or foaming began to subside. After 1 week, the affected area basically healed without leaving a scar.
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:
  • An ointment for quickly repairing burn wounds including:

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

一种修复烧烫伤创面的软膏剂，包括凡士林18-20重量份、甘油8-12重量份、尿囊素1-2重量份、硬脂酸甘油酯15-25重量份、山茶油0.5-1重量份、蒸馏水10-20重量份、翠羽草提取物0.1-0.2重量份、冬青皮提取物0.1-0.2重量份和紫草提取物0.1-0.2重量份。

Description

快速修复烧烫伤创面的软膏剂 技术领域
本发明涉及一种烧烫伤修复剂，具体涉及一种快速修复烧烫伤创面的软膏剂。
背景技术
现有市面上的治疗烧烫伤的药膏一般都含有一些激素成分，当使用一些药效较重的成分后，虽然可以加快治愈的速度，但同时也会带来一些副作用。当皮肤被烧伤或烫伤后，应该及时治疗处理，否则会大大拖延皮肤恢复的速度，甚至造成留疤等影响。
发明内容
针对现有技术的不足之处，本发明的目的在于提供一种快速修复烧烫伤创面的软膏剂，其能有效对中度以下的皮肤烧烫伤进行修复治疗，且对人体皮肤无刺激、无副作用。
本发明的技术方案概述如下：
一种快速修复烧烫伤创面的软膏剂，其包括：
Figure PCTCN2016083897-appb-000001
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的地榆提取物。
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的白蔹提取物。
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的儿茶提取物。
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的金银花提取物。
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的苍术提取物。
优选的是，所述的快速修复烧烫伤创面的软膏剂，其中，还包括有0.1-0.2重量份的白芷提取物。
本发明的有益效果是：本案通过对常规的烧烫伤药膏产品配方进行改进和优化，引入了翠羽草提取物、冬青皮提取物和紫草提取物等皮肤修复型中药成分，有效提高了对烧烫伤皮肤患处的自我恢复功能，且优化后的配方对人体温和无刺激，无副作用，适合婴幼儿使用。
具体实施方式
下面结合实施例对本发明做进一步的详细说明，以令本领域技术人员参照说明书文字能够据以实施。
本案提出一实施例的快速修复烧烫伤创面的软膏剂，其包括：
Figure PCTCN2016083897-appb-000002
这里的中药提取物，例如翠羽草提取物、冬青皮提取物、紫草提取物等 指的是将相应中药经溶剂萃取后，再将萃取溶剂除去后所得到的固体物。
作为本案另一实施例，其中，还优选包括有0.1-0.2重量份的地榆提取物。
在上述实施例中，还优选包括有0.1-0.2重量份的白蔹提取物。
在上述实施例中，还优选包括有0.1-0.2重量份的儿茶提取物。
在上述实施例中，还优选包括有0.1-0.2重量份的金银花提取物。
在上述实施例中，还优选包括有0.1-0.2重量份的苍术提取物。
在上述实施例中，还优选包括有0.1-0.2重量份的白芷提取物。
本案将地榆提取物、白蔹提取物、儿茶提取物、金银花提取物、苍术提取物和白芷提取物与翠羽草提取物、冬青皮提取物、紫草提取物组合使用，作为一个整体，它们可以产生协效作用，协同提高软膏剂对烧烫伤患处的修复功能。根据体感测试，当涂覆本案的软膏剂于患处半天后，痛感显著下降，2天后，痛感几乎消失，红肿处或起泡处开始消退，1周后患处基本愈合，且不留疤留痕。
实施例1
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000003
实施例2
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000004
Figure PCTCN2016083897-appb-000005
实施例3
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000006
实施例4
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000007
Figure PCTCN2016083897-appb-000008
实施例5
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000009
实施例6
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000010
实施例7
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000011
实施例8
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000012
实施例9
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000013
实施例10
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000014
实施例11
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000015
实施例12
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000016
Figure PCTCN2016083897-appb-000017
实施例13
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000018
实施例14
一种快速修复烧烫伤创面的软膏剂，包括：
Figure PCTCN2016083897-appb-000019
Figure PCTCN2016083897-appb-000020
尽管本发明的实施方案已公开如上，但其并不仅仅限于说明书和实施方式中所列运用，它完全可以被适用于各种适合本发明的领域，对于熟悉本领域的人员而言，可容易地实现另外的修改，因此在不背离权利要求及等同范围所限定的一般概念下，本发明并不限于特定的细节和这里示出的实施例。

Claims (7)

  1. 一种快速修复烧烫伤创面的软膏剂，其特征在于，包括：
    Figure PCTCN2016083897-appb-100001
  2. 根据权利要求1所述的快速修复烧烫伤创面的软膏剂，其特征在于，还包括有0.1-0.2重量份的地榆提取物。
  3. 根据权利要求2所述的快速修复烧烫伤创面的软膏剂，其特征在于，还包括有0.1-0.2重量份的白蔹提取物。
  4. 根据权利要求3所述的快速修复烧烫伤创面的软膏剂，其特征在于，还包括有0.1-0.2重量份的儿茶提取物。
  5. 根据权利要求4所述的快速修复烧烫伤创面的软膏剂，其特征在于，还包括有0.1-0.2重量份的金银花提取物。
  6. 根据权利要求5所述的快速修复烧烫伤创面的软膏剂，其特征在于，还包括有0.1-0.2重量份的苍术提取物。
  7. 根据权利要求6所述的快速修复烧烫伤创面的软膏剂，其特征在于，还 包括有0.1-0.2重量份的白芷提取物。
PCT/CN2016/083897 2016-05-30 2016-05-30 快速修复烧烫伤创面的软膏剂 WO2017206017A1 (zh)

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