WO2017166693A1 - 血气分析仪及其血气生化测试卡 - Google Patents

血气分析仪及其血气生化测试卡 Download PDF

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Publication number
WO2017166693A1
WO2017166693A1 PCT/CN2016/097626 CN2016097626W WO2017166693A1 WO 2017166693 A1 WO2017166693 A1 WO 2017166693A1 CN 2016097626 W CN2016097626 W CN 2016097626W WO 2017166693 A1 WO2017166693 A1 WO 2017166693A1
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Prior art keywords
liquid
test
test card
pipe
blood gas
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PCT/CN2016/097626
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English (en)
French (fr)
Inventor
朱志华
王继华
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广州万孚生物技术股份有限公司
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Publication of WO2017166693A1 publication Critical patent/WO2017166693A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Definitions

  • the invention relates to the technical field of medical technology, in particular to a blood gas analyzer and a blood gas biochemical test card thereof.
  • the blood gas biochemical test card is widely used in the medical industry.
  • the test card integrates the biochemical test electrode, and is calibrated by the calibration liquid in the reagent package, and then the test liquid is tested. After the test is completed, in order to prevent the calibration liquid and the test liquid from being
  • the suction port flows out, and the suction port of the test card is generally sealed by a sealing plug.
  • the syringe on the vacuum pump in the instrument needs to pierce the sealing plug to communicate with the pipe in the test card. During the piercing process, the sealing plug is prone to debris, and the debris easily flows with the calibration solution.
  • test tube On the test electrode, the test tube is untested and the test card is scrapped; and after the test card is completed, the injection needle needs to be separated from the sealing plug, and the sealing plug has been pierced and there is a puncture and perforation, so the sealing plug cannot completely seal the piercing and perforation.
  • the test solution flows out from the piercing hole, causing a hidden danger of liquid contamination.
  • the object of the present invention is to provide a blood gas analyzer and a blood gas biochemical test card, which can avoid the problem of liquid leakage and pollution, and eliminate the hidden danger of test scrapping caused by debris contaminating the electrode.
  • a blood gas biochemical test card comprises at least a test card body provided with an inlet, a suction port and a liquid pipe, and an electrode circuit board disposed on the main body of the test card, the liquid pipe includes a waste liquid chamber, and one end is connected to the injection port.
  • the waste liquid chamber comprises at least a first waste liquid chamber and a second waste liquid chamber arranged side by side, and connected a liquid discharge port of the first waste liquid chamber and the second waste liquid chamber, the first waste liquid chamber is provided with a liquid inlet connected to the electrode pipe, and the second waste liquid chamber is provided with a liquid outlet connected to the suction port, and the liquid is discharged
  • the mouth is located above the inlet.
  • the suction port is separated from the external device, and the calibration liquid is stored in the first waste liquid chamber.
  • a liquid discharge port is arranged between a waste liquid chamber and the second waste liquid chamber, and a cross section difference exists between the liquid discharge port and the waste liquid chamber, and the calibration liquid cannot flow from the first waste liquid chamber to the second waste liquid due to the liquid tension of the liquid.
  • the liquid is further prevented from leaking out of the suction port.
  • the air suction port of the invention does not need to be provided with a sealing plug, and the external device directly communicates with the air suction port, and there is no problem of chipping due to piercing the sealing plug, and the hidden danger of the test scrapping caused by the debris contamination is eliminated. .
  • the test card body is further provided with a calibration liquid port
  • the liquid pipeline further comprises a calibration liquid pipeline connected with the test liquid pipeline and the electrode pipeline, and the liquid level of the calibration liquid pipeline is higher than the liquid surface of the test liquid.
  • the calibration liquid port is separated from the external device, and the test liquid is stored in the electrode pipe and the calibration liquid pipe. Since the liquid level of the calibration liquid pipe is higher than the liquid level of the test liquid, no external force is applied. The test solution cannot flow through the highest level of the calibrator pipe, and the liquid will not leak from the calibrator port to prevent liquid contamination.
  • the calibration liquid port of the invention does not need to be provided with a sealing plug, and the external device directly communicates with the calibration liquid port, and there is no problem of debris generated by piercing the sealing plug, and the debris is contaminated by the electrode. Test the hidden dangers of retirement.
  • the liquid level of the calibrator pipe is recessed with a leak-proof groove with an opening facing upward.
  • a support column is disposed in the first waste liquid chamber and the second waste liquid chamber, and the liquid discharge port is close to the top of the first waste liquid chamber or the second waste liquid chamber.
  • the blood gas biochemical test card further includes an electrode test slot, and the bottom of the electrode tube is connected to the electrode circuit board through the electrode test slot.
  • the liquid inlet is disposed at the bottom of the first waste liquid chamber, and the liquid outlet is disposed at the top of the second waste liquid chamber.
  • the liquid suction port communicating with the liquid outlet can prevent liquid leakage and further prevent liquid contamination.
  • the blood gas biochemical test card further comprises a sealing film for the pressing member and the closed liquid pipe, the sealing film is an elastic composite film, and the opposite surface of the test liquid pipe and the sealing film is provided with a groove, and the sealing film is located Between the groove and the pressing member, the pressing member is provided with a pressing head that matches the shape of the groove.
  • the pressing member presses the sealing film to the groove side, the test liquid pipe is closed; the sealing film is an elastic composite film, and when the pressing member leaves the sealing film, the sealing film is separated from the groove by its own elastic deformation, and the test is performed.
  • the liquid pipe is opened.
  • the groove is arranged in the test liquid pipe, and is integrated with the test liquid pipe, there is no excess cavity, no air bubbles remain, and the amount of the test liquid is reduced, and the test accuracy is improved; there is no need to set the on/off switch rubber plug and the test card body
  • the sealing film covering the channel switch rubber plug avoids gas leakage problems, reduces the number of parts, facilitates production, and reduces product defect rate.
  • the sealing film comprises a film, an elastic silicone film and a PET film, and the film is adhered between the test card body and the elastic silicone film, and the PET film covers the side of the elastic silicone film facing away from the groove.
  • the film acts as an adhesive sealing film and the main body of the test card, so that the tubes of the test card are closed;
  • the elastic silicone film acts as a sealing, and is filled into the groove of the test card body by the elasticity of the elastic silicone film itself;
  • the PET film supports and The resetting action ensures that the sealing film can be effectively reset after the external force is removed while the sealing film is deformed, and the sealing film adopts a flat and large-surface film sealing method to seal the liquid pipeline in the entire test card, thereby further avoiding the gas leakage problem.
  • the bottom of the groove is provided with a protrusion that protrudes toward one side of the sealing film.
  • the protrusion is embedded in the sealing film to make the sealing effect of the test liquid pipe better.
  • the invention also provides a blood gas analyzer, comprising a reagent package, a pump and a blood gas biochemical test card, wherein the reagent package is provided with a first pin connected to the calibration liquid port, and the pump is provided with a second pin connected to the air suction port.
  • the calibration liquid is extracted, and when the electrode is calibrated, the test liquid pipeline is closed, and the reagent package works to connect the calibration liquid pipeline in the reagent package with the calibration liquid inlet, the pump is connected with the suction port, and the pump works to generate a negative pressure in the liquid pipeline. Therefore, the calibrating solution flows from the reagent bag into the calibration liquid pipe and the electrode pipe of the test card; after the calibration is completed, the reagent package rotates to make the air pipe in the reagent bag communicate with the calibration liquid port, and the pump continues to work.
  • Negative pressure is generated in the liquid pipe, so that the air flows from the reagent bag into the calibration liquid pipe and the electrode pipe, and the calibration liquid is pumped into the waste liquid cavity; after that, the test liquid is extracted, the test liquid pipe is opened, and the reagent package works to make the reagent
  • the inner pipe and the calibration liquid port are closed, and the pump continues to work to generate a negative pressure in the liquid pipe, so that the test liquid flows from the inlet into the test liquid pipe and the electrode pipe, and the test liquid is tested;
  • the blood gas biochemical test card's blood gas analyzer can avoid liquid leakage and pollution problems, and eliminate the hidden dangers of test scrapping caused by debris contamination of the electrode.
  • the blood gas analyzer further comprises a sealing member, the sealing member is sleeved on the first pin and the second pin, and the outer wall of the test card body is provided with a sealing groove matching the shape of the sealing member.
  • the blood gas analyzer is better in preventing liquid leakage.
  • the sealing member is sealed on the first pin and the second pin, respectively, and separated from the test card body to ensure the sealing, and Avoid eliminating debris from contaminating the electrode and causing hidden dangers of test rejection.
  • the present invention has the following beneficial effects:
  • the air suction port and the calibration liquid port are separated from the external device, the calibration liquid is stored in the waste liquid cavity, and the test liquid is stored in the electrode pipe and the calibration liquid pipe, because the liquid outlet of the waste liquid chamber is located Above the inlet port, under the action of no external force, the calibration solution cannot flow out from the outlet, and the suction port connected to the outlet port will not leak liquid and prevent liquid contamination; and the liquid level of the calibration liquid pipeline is the highest. The liquid level is higher than the liquid level of the test liquid. Under the action of no external force, the test liquid cannot flow through the highest liquid level of the calibration liquid pipeline, and the liquid will not leak from the calibration liquid outlet to prevent liquid contamination.
  • FIG. 1 is a schematic structural view of a blood gas biochemical test card according to an embodiment of the present invention
  • Figure 2 is a cross-sectional view taken along line A-A of Figure 1;
  • FIG. 3 is an enlarged view of I of Figure 2;
  • FIG. 4 is a schematic structural view of a blood gas analyzer according to an embodiment of the present invention.
  • FIG. 5 is a schematic view showing a first working state of a blood gas analyzer according to an embodiment of the present invention
  • FIG. 6 is a schematic view showing a second working state of a blood gas analyzer according to an embodiment of the present invention.
  • Fig. 7 is a schematic view showing the third working state of the blood gas analyzer according to the embodiment of the present invention.
  • Test card body 110. Inlet, 120. Pumping port, 130. Liquid pipe, 131. Test liquid pipe, 1311. Groove, 1312. Protrusion, 132. Calibration liquid pipe, 1321. Calibration liquid Mouth, 1322. Leakproof tank, 1323. Top, 133. Waste chamber, 1331. Inlet, 1332. Outlet, 1333. Discharge port, 1334. First waste chamber, 1335. Second waste chamber, 134. Electrode tube, 135. Waste tube, 140. Support column, 150. Electrode test slot, 160. Seal, 170. Sealing groove, 20. Electrode line Plate, 40. Pressing piece, 410. Indenter, 50. Sealing film, 510. Film, 520. Elastic silicone film, 530. PET film, 60. Syringe, 70. Syringe, 80. Reagent bag, 810 .First pin, 90. pump, 910. Second pin.
  • a blood gas biochemical test card includes at least a test card body 10 provided with an inlet 110, a calibrated liquid port 1321 and a suction port 120, and a liquid pipe disposed on the test card body 10.
  • the liquid pipe 130 includes a test liquid pipe 131, a calibrating liquid pipe 132, a waste liquid chamber 133, and an electrode pipe 134 connected to the electrode circuit board 20, the test liquid
  • One end of the pipe 131 communicates with the inlet 110, the other end communicates with the calibration liquid pipe 132 and the electrode pipe 134, and one end of the calibration liquid pipe 132 away from the test liquid pipe 131 communicates with the calibration liquid port 1321, and the electrode pipe 134 is far away from the test.
  • One end of the liquid pipe 131 communicates with the liquid inlet 1331 of the waste liquid chamber 133, the liquid outlet 1332 of the waste liquid chamber 133 communicates with the suction port 120, and the liquid outlet 1332 is located above the liquid inlet 1331, and the calibration liquid pipe 132 The highest level is above the level of the test solution.
  • the air suction port 120 and the calibration liquid port 1321 are separated from the external device, the calibration liquid is stored in the waste liquid chamber 133, and the test liquid is stored in the electrode pipe 134 and the calibration liquid pipe 132, due to the waste liquid chamber 133
  • the liquid outlet 1332 is located above the liquid inlet 1331, and the calibration liquid cannot flow out from the liquid outlet 1332 without external force, so that the liquid outlet 120 communicating with the liquid outlet 1332 does not leak liquid and prevent liquid contamination;
  • the highest liquid level of the calibration liquid pipe 132 that is, the top portion 1323 of the pipe is higher than the liquid surface of the test liquid, and the test liquid cannot flow through the highest liquid level of the calibration liquid pipe 132 without external force, and the liquid does not pass from the liquid level of the calibration liquid pipe 132.
  • the calibration liquid port 1321 leaks to prevent liquid contamination. Compared with the conventional test card, there is no need to provide a sealing plug on the calibration liquid port 1321 and the suction port 120 of the present invention, and the external device directly communicates with the calibration liquid port 1321 and the suction port 120, and there is no piercing of the sealing plug. The problem of chipping is eliminated, and the hidden contamination of the electrode caused by the debris is eliminated.
  • the waste liquid chamber 133 includes a first waste liquid chamber 1334 and a second waste arranged side by side.
  • the liquid chamber 1335 is connected to the first waste liquid chamber 1334 and the liquid discharge port 1333 of the second waste liquid chamber 1335.
  • the bottom of the first waste liquid chamber 1334 is provided with a liquid inlet 1331, and the top of the second waste liquid chamber 1335 is provided with a liquid chamber 1333.
  • the liquid port 1332 and the liquid discharge port 1333 are located on the side close to the liquid outlet 1332.
  • the calibrator is stored in the first waste liquid chamber 1334, a liquid discharge port 1333 is disposed between the first waste liquid chamber 1334 and the second waste liquid chamber 1335, and the liquid discharge port 1333 is located near the liquid discharge port 1332.
  • One side of the first waste liquid chamber 1334 and the second waste liquid chamber 1335 are connected, and there is a difference in section between the liquid discharge port 1333 and the waste liquid chamber 133, and the calibration liquid cannot easily be removed from the first waste due to its own liquid tension.
  • the liquid chamber 1334 flows into the second waste liquid chamber 1335 to further prevent liquid from leaking out of the suction port 120.
  • the waste liquid chamber 133 can also be set to more than one according to actual needs.
  • the liquid pipe 130 further includes a waste liquid pipe 135, and a waste liquid pipe 135 is connected between the liquid discharge port 1332 and the air suction port 120.
  • the top portion 1323 of the calibrating fluid conduit 132 is recessed with a leak-proof groove 1322 with an opening facing upward.
  • the leakage preventing groove 1322 can also be disposed between the top portion 1323 of the calibrating liquid pipe 132 and the end of the calibrating liquid pipe 132 connected to the test liquid pipe 131 according to actual needs.
  • the blood gas biochemical test card further includes an electrode test slot 150, and the bottom of the electrode duct 134 is connected to the electrode circuit board 20 through the electrode test slot 150.
  • the blood gas biochemical test card further includes a pressing member 40.
  • the sealing film 50 is an elastic composite film, and the opposite surface of the testing liquid pipe 131 and the sealing film 50 is provided with a groove 1311, and the sealing film 50 is located in the concave shape. Between the groove 1311 and the abutting member 40, the pressing member 40 is provided with a ram 410 that is shaped to match the groove 1311.
  • the test liquid pipe 131 is closed; when the pressing member 40 leaves the sealing film 50, the sealing film 50 is elastically deformed away from the groove 1311 by itself.
  • the test liquid pipe 131 is opened.
  • the groove 1311 is disposed in the test liquid pipe 131, and is integrated with the test liquid pipe 131. There is no excess cavity, no air bubbles remain, and the amount of the test liquid is reduced, and the test accuracy is improved; the switch card body 10 does not need to be provided with an on/off switch.
  • the rubber plug and the sealing film for covering the channel switch rubber plug avoid leakage problems, reduce the number of parts, facilitate production, and reduce product defect rate.
  • the sealing film 50 includes a film 510, an elastic silicone film 520, and a PET film 530.
  • the film 510 is adhered between the test card body 10 and the elastic silicone film 520.
  • the film 530 covers the side of the elastic silicone film 520 facing away from the groove 1311.
  • the adhesive film 510 functions as the adhesive sealing film 50 and the test card main body 10, so that the test card pipes are closed; the elastic silicone film 520 acts as a sealing, and is filled into the groove 1311 by the elasticity of the elastic silicone film 520 itself; the PET film 530
  • the support film and the resetting function ensure that the sealing film 50 is deformed while ensuring effective sealing of the sealing film 50 after the external force is eliminated, and the sealing film 50 seals the liquid pipe 130 in the entire test card by a flat and large-surface filming method, further avoiding Air leak problem.
  • the sealing film 50 can also adopt other structural forms according to actual needs.
  • the bottom of the groove 1311 is provided with a projection 1312 which is convex toward the side of the sealing film, and the projection has a rib shape.
  • the projection 1312 is fitted into the sealing film 50 to make the sealing effect of the test liquid pipe 131 better.
  • two support columns 140 are disposed in the first waste liquid chamber 1334 and the second waste liquid chamber 1335.
  • the test film 50 is prevented from being trapped in the waste liquid chamber 133 when the test card is evacuated through the suction port 120.
  • the first waste liquid chamber 1334 and the second waste liquid chamber 1335 can also be provided with more than one support column 140 according to actual needs.
  • the blood gas biochemical test card further includes a syringe 60 that is fixed to the inlet 110 of the test card body 10 and communicates with the syringe 70, and the test solution is stored in the syringe 70.
  • the present invention further provides a blood gas analyzer comprising a reagent package 80, a pump 90 and a blood gas biochemical test card.
  • the reagent package 80 is provided with a first pin 810 communicating with the calibration liquid port 1321, and the pump 90
  • a second pin 910 is provided in communication with the suction port 120.
  • the test liquid pipe 131 is closed, and the reagent bag 80 is operated to connect the calibration liquid pipe 132 in the reagent package 80 with the calibration liquid port 1321, and the pump 90 and the suction port. 120 is connected, the pump 90 works to generate a negative pressure in the liquid pipe 130, so that the calibrating liquid flows from the reagent bag 80 into the calibration liquid pipe 132 and the electrode pipe 134 of the test card; as shown in FIG. 6, the calibration is completed.
  • the reagent pack 80 operates to allow the air conduit in the reagent pack 80 to communicate with the calibrated fluid port 1321, and the pump 90 continues to operate to create a negative pressure within the liquid conduit 130, thereby allowing air to flow from the reagent pack 80 to the reagent pack 80.
  • the calibration liquid pipe 132 and the electrode pipe 134 the calibration liquid is pumped into the first waste liquid chamber 1334; after that, the test liquid is extracted, as shown in FIG. 7, the test liquid pipe 131 is opened, and the reagent package 80 is operated to make the reagent package 80.
  • the inner pipe and the calibration liquid port 1321 are closed, and the pump 90 continues to operate to generate a negative pressure in the liquid pipe 130, so that the test liquid flows from the inlet 110 into the test liquid pipe 131 and the electrode pipe 134 to test the test liquid;
  • the blood gas analyzer with the blood gas biochemical test card can avoid liquid leakage and contamination problems, and eliminate the hidden dangers of test scrapping caused by debris contaminated electrodes.
  • the blood gas analyzer further includes a sealing member 160.
  • the sealing member 160 is sleeved on the first pin 810 and the second pin 910, and the outer wall of the test card body 10 is provided with the shape of the sealing member 160. Matching seal groove 170. The effect of preventing blood leakage of the blood gas analyzer is better.
  • the sealing member 160 of the present invention is sealed on the first pin 810 and the second pin 910, respectively, and separated from the test card body 10. Under the premise of ensuring the seal, it also avoids the hidden dangers of test scrapping caused by debris contamination of the electrode.
  • the needle positions of the first pin 810 and the second pin 910 do not need to pierce the sealing plug, but communicate with the calibration liquid port 1321 and the air suction port 120 respectively, the needle position can be set to be pointed or Set to other shapes such as flat head.
  • first pin 810 and the second pin 910 are sealed by the same sealing member 160, and the blood gas analyzer can also be sleeved on the first pin 810 and the second pin 910 according to actual needs.
  • a sealing member, the outer wall of the test card body 10 is provided with a sealing groove corresponding to the sealing member.
  • the blood gas analyzer further includes a driving device (not shown) that drives the ram 410 to reciprocate toward the side of the recess 1311.
  • the movement of the pressing member 40 is driven by the driving device to make the operation of the blood gas analyzer simpler.
  • the driving device is a motor and the pump 90 is a vacuum pump.
  • the drive unit and pump 90 can also be configured in other forms as needed.

Abstract

一种血气分析仪及其血气生化测试卡（10），至少包括设有进样口（110）、抽气口（120）和液体管道（130）的测试卡主体（10）、设置于测试卡主体（10）上的电极线路板（20），液体管道（130）包括废液腔（133）、一端与进样口（110）连通的测试液管道（131）、两端分别与废液腔（133）和测试液管道（131）连通的电极管道（134），电极管道（134）与电极线路板（20）相接，废液腔（133）至少包括并排布置的第一废液腔（1334）和第二废液腔（1335）、连通第一废液腔（1334）和第二废液腔（1335）的排液口（1333），第一废液腔（1334）设有与电极管道（134）连通的进液口（1331），第二废液腔（1335）设有与抽气口（120）连通的出液口（1332），出液口（1332）位于进液口（1331）的上方，排液口（1333）位于靠近出液口（1332）的一侧。抽气口（120）上均无需设置密封塞，外部装置直接与抽气口（120）连通，不存在因刺穿密封塞而产生碎屑的问题，消除碎屑污染电极造成测试报废的隐患。

Description

血气分析仪及其血气生化测试卡 技术领域
本发明涉及医疗技术领域，特别涉及一种血气分析仪及其血气生化测试卡。
背景技术
血气生化测试卡广泛用于医疗行业，该测试卡集成生化测试电极，通过试剂包内的定标液进行定标，然后对测试液进行测试，测试完成后，为了防止定标液和测试液从该抽气口中流出，测试卡的抽气口一般由密封塞密封。但在测试过程中，仪器内的真空泵上的进样针需刺穿密封塞才能与测试卡内的管道连通，在刺穿过程中密封塞容易产生碎屑，碎屑容易随定标液流到测试电极上，造成电极无法测试造成测试卡报废；且测试卡测试完成后，进样针需脱离密封塞，因密封塞已被刺穿而存在刺穿孔，故存在密封塞不能完全密封刺穿孔造成测试液从该刺穿孔流出，造成液体污染的隐患。
发明内容
本发明的目的在于提供一种血气分析仪及其血气生化测试卡，能够避免液体泄漏和污染的问题，并消除碎屑污染电极造成测试报废的隐患。
为实现本发明的目的，采取的技术方案是：
一种血气生化测试卡，至少包括设有进样口、抽气口和液体管道的测试卡主体、设置于测试卡主体上的电极线路板，液体管道包括废液腔、一端与进样口连通的测试液管道、两端分别与废液腔和测试液管道连通的电极管道，电极管道与电极线路板相接，废液腔至少包括并排布置的第一废液腔和第二废液腔、连通第一废液腔和第二废液腔的排液口，第一废液腔设有与电极管道连通的进液口，第二废液腔设有与抽气口连通的出液口，出液口位于进液口的上方。
完成测试后，抽气口与外部装置脱离，定标液储存在第一废液腔内，第 一废液腔和第二废液腔之间设置了排液口，排液口和废液腔之间存在截面差，定标液因自身液体张力无法从第一废液腔流入第二废液腔内，进一步防止液体从抽气口泄漏出来。与传统的测试卡相比，本发明的抽气口无需设置密封塞，外部装置直接与抽气口连通，不存在因刺穿密封塞而产生碎屑的问题，消除碎屑污染电极造成测试报废的隐患。
下面对技术方案进一步说明：
进一步的是，测试卡主体还设有定标液口，液体管道还包括与测试液管道、电极管道相连通的定标液管道，定标液管道的液位最高处高于测试液的液面。完成测试后，定标液口与外部装置脱离，测试液储存在电极管道和定标液管道内，由于定标液管道的液位最高处高于测试液的液面，在无外力的作用下测试液无法流过定标液管道的液位最高处，液体不会从定标液口泄露，防止液体污染。与传统的测试卡相比，本发明的定标液口无需设置密封塞，外部装置直接与定标液口连通，不存在因刺穿密封塞而产生碎屑的问题，消除碎屑污染电极造成测试报废的隐患。
进一步的是，定标液管道的液位最高处凹设有开口朝上的防漏槽。防漏槽与定标液管道之间存在截面差，测试液因自身液体张力无法从防漏槽中流出，进一步防止液体从定标液口泄露出来。
进一步的是，第一废液腔内和第二废液腔内均设有支撑柱，排液口靠近第一废液腔或第二废液腔的顶部。通过设置支撑柱，防止测试卡在通过抽气口进行抽气时，测试卡上的密封膜陷入废液腔内，且通过将排液口设置在靠近第一废液腔或第二废液腔的顶部，进一步防止液体从抽气口泄漏出来。
进一步的是，血气生化测试卡还包括电极测试槽，电极管道的底部通过电极测试槽与电极线路板相接。
进一步的是，进液口设于第一废液腔的底部，出液口设于第二废液腔的顶部。在无外力的作用下定标液无法从出液口流出，则与出液口连通的抽气口不会出现液体泄露，进一步防止液体污染。
进一步的是，血气生化测试卡还包括抵压件和封闭液体管道的密封膜，密封膜为弹性复合膜，测试液管道与密封膜的相对面设有凹槽，密封膜位于 凹槽和抵压件之间，抵压件设有与凹槽形状匹配的压头。当抵压件挤压密封膜向凹槽一侧贴合，测试液管道实现关闭；密封膜为弹性复合膜，当挤压件离开密封膜时，密封膜靠自身的弹性变形离开凹槽，测试液管道实现打开。凹槽设置在测试液管道中，与测试液管道构成一体，不存在多余空腔，不残留气泡，同时减少测试液用量，提高测试准确性；测试卡主体上无需设置通断开关胶塞和用于覆盖通道开关胶塞的密封膜，避免漏气问题，减少零件数量，便于生产，降低产品不良率。
进一步的是，密封膜包括胶膜、弹性硅胶膜和PET膜，胶膜粘接在测试卡主体和所述弹性硅胶膜之间，PET膜覆盖于弹性硅胶膜背向凹槽的一侧。胶膜起粘合密封膜与测试卡主体的作用，使测试卡各管道封闭；弹性硅胶膜起密封作用，靠弹性硅胶膜自身的弹性填充到测试卡主体的凹槽内；PET膜起支撑及复位作用，使密封膜在变形的同时保证密封膜在外力消除后实现有效复位，且密封膜采用平面及大面贴膜方式将整个测试卡内的液体管道密封，进一步避免漏气问题。
进一步的是，凹槽底部设有向密封膜一侧凸起的突起部。密封膜填充到凹槽上时，突起部镶入密封膜内，使测试液管道的密闭效果更好。
本发明还提供一种血气分析仪，包括试剂包、泵和血气生化测试卡，试剂包设有与定标液口连通的第一插针，泵设有与抽气口连通的第二插针。
抽取定标液，对电极进行定标时，关闭测试液管道，试剂包工作使试剂包内定标液管道与定标液口连通，泵与抽气口连通，泵工作使液体管道内产生负压，从而使定标液从试剂包内流入到测试卡的定标液管道及电极管道内；定标完成后，试剂包旋工作使试剂包内的空气管道与定标液口连通，泵继续工作使液体管道内产生负压，从而使空气从试剂包流入到定标液管道及电极管道内，定标液被抽到废液腔内；之后抽取测试液，打开测试液管道，试剂包工作使试剂包内管道与定标液口关闭，泵继续工作使液体管道内产生负压，从而使测试液从进样口流入测试液管道及电极管道内，对测试液进行测试；测试完成后，具有该血气生化测试卡的血气分析仪，能够避免液体泄漏和污染的问题，并消除碎屑污染电极造成测试报废的隐患。
进一步的是，血气分析仪还包括密封件，密封件套设于第一插针和第二插针上，测试卡主体的外壁设有与密封件形状匹配的密封槽。使血气分析仪的防止液体泄漏的效果更好，与传统的血气分析仪相比，密封件分别密封在第一插针和第二插针，与测试卡主体分离，保证密封的前提下，又避免消除碎屑污染电极造成测试报废的隐患。
与现有技术相比，本发明具有以下有益效果：
本发明完成测试后，抽气口和定标液口与外部装置脱离，定标液储存在废液腔内，测试液储存在电极管道和定标液管道内，由于废液腔的出液口位于进液口的上方，在无外力的作用下定标液无法从出液口流出，则与出液口连通的抽气口不会出现液体泄露，防止液体污染；且定标液管道的液位最高处高于测试液的液面，在无外力的作用下测试液无法流过定标液管道的液位最高处，液体不会从定标液口泄露，防止液体污染。与传统的测试卡相比，定标液口和抽气口上均无需设置密封塞，外部装置直接与定标液口和抽气口连通，不存在因刺穿密封塞而产生碎屑的问题，消除碎屑污染电极造成测试报废的隐患。
附图说明
图1是本发明实施例血气生化测试卡的结构示意图；
图2为图1的A-A向截面剖视图；
图3为图2的I处放大图；
图4为本发明实施例血气分析仪的结构示意图；
图5为本发明实施例血气分析仪的第一工作状态示意图；
图6为本发明实施例血气分析仪的第二工作状态示意图；
图7为本发明实施例血气分析仪的第三工作状态示意图。
附图标记说明：
10.测试卡主体，110.进样口，120.抽气口，130.液体管道，131.测试液管道，1311.凹槽，1312.突起部，132.定标液管道，1321.定标液口，1322.防漏槽，1323.顶部，133.废液腔，1331.进液口，1332.出液口，1333.排液口，1334. 第一废液腔，1335.第二废液腔，134.电极管道，135.废液管道，140.支撑柱，150.电极测试槽，160.密封件，170.密封槽，20.电极线路板，40.抵压件，410.压头，50.密封膜，510.胶膜，520.弹性硅胶膜，530.PET膜，60.进样针，70.注射器，80.试剂包，810.第一插针，90.泵，910.第二插针。
具体实施方式
下面结合附图对本发明的实施例进行详细说明：
如图1和图2所示，一种血气生化测试卡，至少包括设有进样口110、定标液口1321和抽气口120的测试卡主体10、设置于测试卡主体10上的液体管道130和电极线路板20、封闭液体管道130的密封膜50，液体管道130包括测试液管道131、定标液管道132、废液腔133和与电极线路板20相接的电极管道134，测试液管道131的一端与进样口110连通，另一端与定标液管道132和电极管道134连通，定标液管道132远离测试液管道131的一端与定标液口1321连通，电极管道134远离测试液管道131的一端与废液腔133的进液口1331连通，废液腔133的出液口1332与抽气口120连通，出液口1332位于进液口1331的上方，定标液管道132的液位最高处高于测试液的液面。
完成测试后，抽气口120和定标液口1321与外部装置脱离，定标液储存在废液腔133内，测试液储存在电极管道134和定标液管道132内，由于废液腔133的出液口1332位于进液口1331的上方，在无外力的作用下定标液无法从出液口1332流出，则与出液口1332连通的抽气口120不会出现液体泄露，防止液体污染；且定标液管道132的液位最高处即管道的顶部1323高于测试液的液面，在无外力的作用下测试液无法流过定标液管道132的液位最高处，液体不会从定标液口1321泄露，防止液体污染。与传统的测试卡相比，本发明的定标液口1321和抽气口120上均无需设置密封塞，外部装置直接与定标液口1321和抽气口120连通，不存在因刺穿密封塞而产生碎屑的问题，消除碎屑污染电极造成测试报废的隐患。
在本实施例中，废液腔133包括并排布置的第一废液腔1334和第二废 液腔1335、连通第一废液腔1334和第二废液腔1335的排液口1333，第一废液腔1334的底部设有进液口1331，第二废液腔1335的顶部设有出液口1332，排液口1333位于靠近出液口1332的一侧。测试完成后，定标液储存在第一废液腔1334内，第一废液腔1334和第二废液腔1335之间设置了排液口1333，且排液口1333位于靠近出液口1332的一侧、并连通第一废液腔1334和第二废液腔1335的顶部，排液口1333和废液腔133之间存在截面差，定标液因自身液体张力无法轻易从第一废液腔1334流入第二废液腔1335内，进一步防止液体从抽气口120泄漏出来。废液腔133还可以根据实际需要设置一个以上。
如图1所示，液体管道130还包括废液管道135，出液口1332与抽气口120之间连接有废液管道135。
如图1所示，定标液管道132的顶部1323凹设有开口朝上的防漏槽1322。防漏槽1322与定标液管道132之间存在截面差，测试液因自身液体张力无法从防漏槽1322中流出，进一步防止液体从定标液口1321泄露出来。防漏槽1322还可以根据实际需要设置在定标液管道132的顶部1323和定标液管道132与测试液管道131连接的一端之间。
如图2所示，血气生化测试卡还包括电极测试槽150，电极管道134的底部通过电极测试槽150与电极线路板20相接。
如图2和图5所示，血气生化测试卡还包括抵压件40，密封膜50为弹性复合膜，测试液管道131与密封膜50的相对面设有凹槽1311，密封膜50位于凹槽1311和抵压件40之间，抵压件40设有与凹槽1311形状匹配的压头410。当抵压件40挤压密封膜50向凹槽1311一侧贴合，测试液管道131实现关闭；当挤压件40离开密封膜50时，密封膜50靠自身的弹性变形离开凹槽1311，测试液管道131实现打开。凹槽1311设置在测试液管道131中，与测试液管道131构成一体，不存在多余空腔，不残留气泡，同时减少测试液用量，提高测试准确性；测试卡主体10上无需设置通断开关胶塞和用于覆盖通道开关胶塞的密封膜，避免漏气问题，减少零件数量，便于生产，降低产品不良率。
在本实施例中，如图3所示，密封膜50包括胶膜510、弹性硅胶膜520和PET膜530，胶膜510粘接在测试卡主体10和所述弹性硅胶膜520之间，PET膜530覆盖于弹性硅胶膜520背向凹槽1311的一侧。胶膜510起粘合密封膜50与测试卡主体10的作用，使测试卡各管道封闭；弹性硅胶膜520起密封作用，靠弹性硅胶膜520自身的弹性填充到凹槽1311内；PET膜530起支撑及复位作用，使密封膜50在变形的同时保证密封膜50在外力消除后实现有效复位，且密封膜50采用平面及大面贴膜方式将整个测试卡内的液体管道130密封，进一步避免漏气问题。密封膜50还可以根据实际需要采用其他结构形式。
如图3所示，凹槽1311底部设有向密封膜一侧凸起的突起部1312，突起部呈筋条状。密封膜填充到凹槽1311上时，突起部1312镶入密封膜50内，使测试液管道131的密闭效果更好。
如图1所示，第一废液腔1334内和第二废液腔1335内均设有两个支撑柱140。通过设置支撑柱140，防止测试卡在通过抽气口120进行抽气时，测试卡上的密封膜50陷入废液腔133内。第一废液腔1334和第二废液腔1335还可以根据实际需要设置一个以上支撑柱140。
如图1所示，血气生化测试卡还包括进样针60，进样针60固定到测试卡主体10的进样口110上、并与注射器70连通，测试液存放于注射器70内。
如图4所示，本发明还提供一种血气分析仪，包括试剂包80、泵90和血气生化测试卡，试剂包80设有与定标液口1321连通的第一插针810，泵90设有与抽气口120连通的第二插针910。
如图5所示，抽取定标液，对电极进行定标时，关闭测试液管道131，试剂包80工作使试剂包80内定标液管道132与定标液口1321连通，泵90与抽气口120连通，泵90工作使液体管道130内产生负压，从而使定标液从试剂包80内流入到测试卡的定标液管道132及电极管道134内；如图6所示，定标完成后，试剂包80工作使试剂包80内的空气管道与定标液口1321连通，泵90继续工作使液体管道130内产生负压，从而使空气从试剂包80流入到 定标液管道132及电极管道134内，定标液被抽到第一废液腔1334内；之后抽取测试液，如图7所示，打开测试液管道131，试剂包80工作使试剂包80内管道与定标液口1321关闭，泵90继续工作使液体管道130内产生负压，从而使测试液从进样口110流入测试液管道131及电极管道134内，对测试液进行测试；测试完成后，具有该血气生化测试卡的血气分析仪，能够避免液体泄漏和污染的问题，并消除碎屑污染电极造成测试报废的隐患。
如图1和图4所示，血气分析仪还包括密封件160，密封件160套设于第一插针810和第二插针910上，测试卡主体10的外壁设有与密封件160形状匹配的密封槽170。使血气分析仪的防止液体泄漏的效果更好，与传统的血气分析仪相比，本发明的密封件160分别密封在第一插针810和第二插针910上，与测试卡主体10分离，保证密封的前提下，又避免消除碎屑污染电极造成测试报废的隐患。且第一插针810和第二插针910的针头位置由于无需刺穿密封塞，而是分别与定标液口1321、抽气口120连通，因此针头位置既可以设置呈尖头状，也可以设置为平头等其他形状。
在本实施例中，第一插针810和第二插针910通过同一个密封件160进行密封，血气分析仪还可以根据实际需要分别在第一插针810和第二插针910上套设一个密封件，测试卡主体10的外壁设置与密封件一一对应的密封槽。
血气分析仪还包括驱动压头410向凹槽1311一侧作往复运动的驱动装置(附图未标识)。通过驱动装置驱动抵压件40运动，使血气分析仪的操作更简单。
在本实施例中，驱动装置为电机，泵90为真空泵。驱动装置和泵90还可以根据实际需要设置为其他形式。
以上所述实施例的各技术特征可以进行任意的组合，为使描述简洁，未对上述实施例中的各个技术特征所有可能的组合都进行描述，然而，只要这些技术特征的组合不存在矛盾，都应当认为是本说明书记载的范围。
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出如果 干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。

Claims (11)

  1. 一种血气生化测试卡，其特征在于，至少包括设有进样口、抽气口和液体管道的测试卡主体、设置于所述测试卡主体上的电极线路板，所述液体管道包括废液腔、一端与所述进样口连通的测试液管道、两端分别与所述废液腔和所述测试液管道连通的电极管道，所述电极管道与所述电极线路板相接，所述废液腔至少包括并排布置的第一废液腔和第二废液腔、连通所述第一废液腔和所述第二废液腔的排液口，所述第一废液腔设有与所述电极管道连通的进液口，所述第二废液腔设有与所述抽气口连通的出液口，所述出液口位于所述进液口的上方。
  2. 根据权利要求1所述的血气生化测试卡，其特征在于，所述测试卡主体还设有定标液口，所述液体管道还包括与所述测试液管道、所述电极管道相连通的定标液管道，所述定标液管道的液位最高处高于测试液的液面。
  3. 根据权利要求2所述的血气生化测试卡，其特征在于，所述定标液管道的液位最高处凹设有开口朝上的防漏槽。
  4. 根据权利要求1所述的血气生化测试卡，其特征在于，所述第一废液腔内和所述第二废液腔内均设有支撑柱，所述排液口靠近所述第一废液腔或所述第二废液腔的顶部。
  5. 根据权利要求1所述的血气生化测试卡，其特征在于，还包括电极测试槽，所述电极管道的底部通过所述电极测试槽与所述电极线路板相接。
  6. 根据权利要求1至5任一项所述的血气生化测试卡，其特征在于，所述进液口设于所述第一废液腔的底部，所述出液口设于所述第二废液腔的顶部。
  7. 根据权利要求1至5任一项所述的血气生化测试卡，其特征在于，还包括抵压件和封闭所述液体管道的密封膜，所述密封膜为弹性复合膜，所述测试液管道与所述密封膜的相对面设有凹槽，所述密封膜位于所述凹槽和所述抵压件之间，所述抵压件设有与所述凹槽形状匹配的压头。
  8. 根据权利要求7所述的血气生化测试卡，其特征在于，所述密封膜包括胶膜、弹性硅胶膜和PET膜，所述胶膜粘接在所述测试卡主体和所述弹 性硅胶膜之间，所述PET膜覆盖于所述弹性硅胶膜背向所述凹槽的一侧。
  9. 根据权利要求7所述的血气生化测试卡，其特征在于，所述凹槽底部设有向所述密封膜一侧凸起的突起部。
  10. 一种血气分析仪，其特征在于，包括试剂包、泵和如权利要求1至8任一项所述的血气生化测试卡，所述测试卡主体还设有定标液口，所述试剂包设有与所述定标液口连通的第一插针，所述泵设有与所述抽气口连通的第二插针。
  11. 根据权利要求10所述的血气分析仪，其特征在于，还包括密封件，所述密封件套设于所述第一插针和所述第二插针上，所述测试卡主体的外壁设有与所述密封件形状匹配的密封槽。
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