WO2017092169A1 - Dynamic blood glucose monitoring device, system and method - Google Patents

Dynamic blood glucose monitoring device, system and method Download PDF

Info

Publication number
WO2017092169A1
WO2017092169A1 PCT/CN2016/071798 CN2016071798W WO2017092169A1 WO 2017092169 A1 WO2017092169 A1 WO 2017092169A1 CN 2016071798 W CN2016071798 W CN 2016071798W WO 2017092169 A1 WO2017092169 A1 WO 2017092169A1
Authority
WO
WIPO (PCT)
Prior art keywords
blood glucose
blood
dynamic
user
monitoring device
Prior art date
Application number
PCT/CN2016/071798
Other languages
French (fr)
Chinese (zh)
Inventor
张贯京
陈兴明
葛新科
Original Assignee
深圳市易特科信息技术有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市易特科信息技术有限公司 filed Critical 深圳市易特科信息技术有限公司
Publication of WO2017092169A1 publication Critical patent/WO2017092169A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors

Definitions

  • the invention relates to the field of life health, and in particular to a dynamic blood glucose monitoring device, system and method for a diabetic patient.
  • Blood glucose testing to measure glucose levels in the blood should be performed daily for patients with fluctuating blood glucose levels. For the diagnosis of patients with severe diabetes or other specialist diseases, repeated blood glucose tests may be repeated within one day, which may result in low blood glucose detection accuracy.
  • blood glucose testing is often performed in hospitals or other medical research institutions, blood glucose monitoring currently uses multiple blood tests to detect blood glucose, while diabetic patients need 3-6 tests a day to meet demand, and the collected blood glucose data are mostly Local storage, unable to achieve blood glucose data docking with the Diabetes Medical Center, can not achieve the doctor's simultaneous monitoring of diabetes patients.
  • the current blood glucose monitoring system cannot continuously monitor the blood glucose data of diabetic patients 24 hours a day, for the doctor to remotely track the blood glucose level of diabetic patients in real time, which is used for daily blood glucose testing by doctors and diabetic patients. Very inconvenient with tracking.
  • the main object of the present invention is to provide a dynamic blood glucose monitoring device, system and method, which aim to solve the problem that the existing blood glucose detection accuracy is not high and the doctor cannot monitor the blood glucose data of the diabetic patient in real time.
  • the present invention provides a dynamic blood glucose monitoring device comprising a blood sampling probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, wherein:
  • the blood collection probe is used for real-time dynamic collection of the user's blood and output to the biochemical reaction sensor, and the biochemical reaction sensor includes a blood glucose oxidase reagent and a circuit resistance;
  • the biochemical reaction sensor is configured to output a changing current signal by causing a blood glucose oxidation reaction of the blood glucose oxidase reagent and the blood drawn by the blood collection probe to cause a change in a resistance value of the circuit resistance;
  • the microcontroller is configured to calculate a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
  • the blood pressure sensor is configured to detect a blood pressure value of the user, and send the blood pressure value of the user to the microcontroller;
  • the microcontroller is further configured to correct an error in the blood glucose concentration value measurement according to a blood pressure value of the user;
  • the wireless communication unit is configured to transmit the corrected blood glucose concentration value to a mobile communication terminal.
  • the dynamic blood glucose monitoring device further comprises a power switch connected to the microcontroller for turning the dynamic blood glucose monitoring device on or off.
  • the dynamic blood glucose monitoring device further includes a miniature battery connected to the microcontroller, the micro battery being a low-radiation, low-power rechargeable lithium battery or a button battery for The dynamic blood glucose monitoring device provides working power.
  • the microcontroller calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor by using a correlation function between the biochemical response sensor output current change and the blood glucose concentration.
  • the microcontroller corrects an error in the measurement of the blood glucose concentration value according to a blood pressure value of the user by using a relationship function between blood pressure and blood sugar of the human body.
  • the present invention also provides a dynamic blood glucose monitoring system including the dynamic blood glucose monitoring device, a mobile communication terminal, and a medical monitoring platform, the dynamic blood glucose monitoring device being connected to the mobile through a wireless network A communication terminal that is connected to the medical monitoring platform via a remote communication network.
  • the mobile communication terminal dynamically displays the corrected blood glucose concentration value on a display screen of the mobile communication terminal, and transmits the corrected blood glucose concentration value to the medical monitoring through the remote communication network
  • the doctor can remotely and dynamically track the user's blood glucose level in real time.
  • the present invention further provides a dynamic blood glucose monitoring method for use in a dynamic blood glucose monitoring device, the device comprising a blood collection probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, the dynamic blood glucose monitoring Methods include:
  • the blood sampling probe dynamically collects the user's blood in real time and outputs it to the biochemical reaction sensor
  • the blood glucose oxidase reagent in the biochemical reaction sensor and the blood drawn by the blood sampling probe cause a blood glucose oxidation reaction to cause a change in a resistance value of a circuit resistance in the biochemical reaction sensor to output a changed current signal;
  • the microcontroller calculates a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
  • the blood pressure sensor detects a blood pressure value of the user, and sends the blood pressure value of the user to the microcontroller;
  • the microcontroller corrects an error in the measurement of the blood glucose concentration value according to a blood pressure value of the user
  • the wireless communication unit transmits the corrected blood glucose concentration value to the mobile communication terminal.
  • the dynamic blood glucose monitoring device is connected to the mobile communication terminal through a wireless network, and the mobile communication terminal is connected to the medical monitoring platform through a remote communication network.
  • the dynamic blood glucose monitoring method further comprises the steps of:
  • the corrected blood glucose concentration value is transmitted to the medical monitoring platform through the remote communication network by the mobile communication terminal, so that the doctor can dynamically and dynamically track the user's blood glucose concentration level in real time.
  • the dynamic blood glucose monitoring device, system and method of the present invention are applied to dynamic blood glucose monitoring of diabetic patients, can improve the accuracy of blood glucose concentration monitoring and realize uninterrupted dynamics 24 hours a day. Monitoring the blood glucose data of diabetic patients for the doctor to remotely track the user's blood glucose concentration level in real time, which provides great convenience for both diabetic patients and doctors to monitor blood glucose data.
  • FIG. 1 is a system architecture diagram of a preferred embodiment of the dynamic blood glucose monitoring system of the present invention
  • Figure 2 is a diagram showing the internal structure of a preferred embodiment of the dynamic blood glucose monitoring device of the present invention
  • FIG. 3 is a flow chart of a preferred embodiment of the dynamic blood glucose monitoring method of the present invention.
  • the present invention provides a dynamic blood glucose monitoring system capable of improving the accuracy of blood glucose concentration monitoring and continuously monitoring blood glucose data of diabetic patients 24 hours a day for a doctor to remotely operate in real time. Tracking the user's blood glucose level provides great convenience for blood glucose data monitored by both diabetics and doctors.
  • FIG. 1 is a system architecture diagram of a preferred embodiment of the dynamic blood glucose monitoring system of the present invention.
  • the dynamic blood glucose monitoring system includes a dynamic blood glucose monitoring device 1, a mobile communication terminal 2, and a medical monitoring platform 3.
  • the dynamic blood glucose monitoring device 1 is connected to the mobile communication terminal 2 via a wireless network 4, which is connected to the medical monitoring platform 3 via a remote communication network 5.
  • the wireless network 4 includes, but is not limited to, a wireless transmission network such as Bluetooth, WiFi, etc.
  • the remote communication network 5 includes, but is not limited to, a wireless transmission network such as a GSM network, a GPRS network, or a CDMA.
  • the dynamic blood glucose monitoring device 1 is a wearable dynamic blood glucose monitoring device worn on a user (for example, a diabetic patient), and can be integrated on a wearable device such as a universal wristwatch or a wristband.
  • the mobile communication terminal 2 includes, but is not limited to, a wireless communication device such as a mobile phone, a personal digital assistant (PDA), a palmtop computer, or the like.
  • the medical monitoring platform 3 is a remote monitoring device or server or the like disposed at the diabetes medical monitoring center.
  • the user refers to a diabetic patient or other patient who needs to dynamically monitor blood glucose levels in real time.
  • the dynamic blood glucose monitoring device 1 is configured to dynamically collect the blood glucose concentration value of the user in real time 24 hours a day, and send the blood glucose concentration value of the user to the mobile communication terminal 2 through the wireless network 4 . Displayed on the screen to let users dynamically understand their blood glucose level.
  • the mobile communication terminal 2 transmits the blood glucose concentration value of the user to the medical monitoring platform 3 set in the diabetes medical monitoring center through the remote communication network 5, so that the doctor can remotely track the blood sugar concentration level of the user in real time.
  • Fig. 2 is an internal structural view of a preferred embodiment of the dynamic blood glucose monitoring device of the present invention.
  • the dynamic blood glucose monitoring device 1 includes, but is not limited to, a power switch 10, a blood collection probe 11, a biochemical reaction sensor 12, a microcontroller 13, a blood pressure sensor 14, and a wireless communication unit 15.
  • the power switch 10, the blood collection probe 11, the biochemical reaction sensor 12, the blood pressure sensor 14, and the wireless communication unit 15 are electrically connected to the microcontroller 13, respectively, and the blood collection probe 11 is further connected to the biochemical reaction sensor 12. .
  • the power switch 10 is configured to turn on or off the dynamic blood glucose monitoring device.
  • the blood collection probe 11 is configured to dynamically collect the user's blood in real time, and send the user's blood to the biochemical. Reaction sensor 12.
  • the blood collection probe 11 automatically penetrates the subcutaneous tissue of the user's wrist and draws blood from the wrist.
  • the blood collection probe 11 is a small probe with micropores, which does not cause a significant pain to the user when piercing the subcutaneous tissue of the user, thereby reducing pain when the user collects blood.
  • the blood of the user can also be sucked from the external blood storage tube by the blood collection probe 11 in real time, and the blood storage tube stores the blood to be detected by the user and dynamically updates the blood in real time.
  • the biochemical reaction sensor 12 includes a blood glucose oxidase reagent and a circuit resistance.
  • the biochemical reaction sensor 12 acquires the collected blood from the blood collection probe 11, the blood glucose oxidase reagent and the biochemical reaction sensor 12
  • the blood glucose oxidation reaction causes a change in the resistance value of the circuit resistance to output a varying current signal, and outputs the current signal to the microcontroller 13.
  • the microcontroller 13 is a microprocessor, a data processing chip, or an information processing unit having data processing functions.
  • the microcontroller 13 is configured to calculate a blood glucose concentration value of the user according to the current signal output by the biochemical reaction sensor 12.
  • the microcontroller 13 calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor 12 by using the biochemical response sensor 12 to output a relationship function between the current change and the blood glucose concentration.
  • the relationship between the current change and the blood glucose concentration is predefined and solidified within the chip of the microcontroller 13.
  • the blood pressure sensor 14 is a miniature blood pressure sensor chip for detecting the pulse pressure value of the human wrist artery, and is closely attached to the wrist artery of the human body to detect the blood pressure of the human body.
  • the blood pressure sensor 14 is configured to detect a blood pressure value of the user from the wrist artery of the user, and send the blood pressure value of the user to the microcontroller 13, the microcontroller 13
  • the error in the measurement of the blood glucose concentration value is corrected based on the blood pressure value of the user.
  • the microcontroller 13 uses the relationship function between the human blood pressure and the blood glucose to correct the error in the blood glucose concentration value measurement according to the blood pressure value of the user, so as to further improve the accuracy of detecting the blood glucose concentration.
  • the relationship between the blood pressure of the human body and blood sugar is predefined and solidified within the chip of the microcontroller 13.
  • the wireless communication unit 15 is a wireless communication interface supporting a wireless transmission network such as Bluetooth or WiFi, and is configured to send the blood glucose concentration value of the user to the mobile communication terminal 2 through the wireless network 4 for mobile communication.
  • the terminal 2 dynamically displays the blood glucose concentration value of the user on the display screen of the mobile communication terminal 2, so that the user dynamically knows his blood glucose concentration level in real time.
  • the mobile communication terminal 2 can also transmit the blood glucose concentration value of the user to the medical monitoring platform 3 through the remote communication network 5, so that the doctor can remotely track the blood glucose concentration level of the user in real time, thereby serving the user and It is convenient for both doctors to dynamically monitor blood sugar levels.
  • the dynamic blood glucose monitoring device 1 further includes a micro battery 16 connected to the microcontroller 13 for providing operating power to the dynamic blood glucose monitoring device 1.
  • the miniature battery 16 is a low-radiation, low-power rechargeable lithium battery or button battery that does not affect the health of the user.
  • the present invention also provides a dynamic blood glucose monitoring method, which can improve the accuracy of blood glucose concentration monitoring and realize continuous monitoring of blood glucose data of diabetic patients 24 hours a day for doctors in real time. Remotely tracking the user's blood glucose level provides great convenience for both diabetics and doctors to monitor blood glucose data.
  • FIG. 3 is a flow chart of a preferred embodiment of the dynamic blood glucose monitoring method of the dynamic blood glucose monitoring device of the present invention.
  • the dynamic blood glucose monitoring method is applied to the dynamic blood glucose monitoring device 1, the mobile communication terminal 2, and the medical monitoring platform 3, and the method includes the following steps S31 to S36.
  • step S31 the blood collection probe 11 dynamically collects the blood of the user in real time and outputs it to the biochemical reaction sensor 12.
  • the microcontroller 13 drives the blood of the automatic blood collection probe 11 on the dynamic blood glucose monitoring device 1 and outputs it to the biochemical reaction sensor 12.
  • the microcontroller 13 controls the blood collection probe 11 to automatically puncture the subcutaneous tissue of the user's wrist and draw blood from the wrist.
  • the blood of the user can also be sucked from the external blood storage tube by the blood collection probe 11 in real time, and the blood storage tube stores the blood to be detected by the user and dynamically updates the blood in real time.
  • Step S32 the blood glucose oxidase reagent in the biochemical reaction sensor 12 and the blood drawn by the blood sampling probe cause a blood glucose oxidation reaction to cause a change in the resistance value of the circuit resistance in the biochemical reaction sensor 12 to output a changed current signal, and The current signal is output to the microcontroller 13.
  • step S33 the microcontroller 13 calculates the blood glucose concentration value of the user based on the current signal output by the biochemical reaction sensor 12.
  • the microcontroller 13 calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor 12 by using the biochemical response sensor 12 to output a relationship function between the current change and the blood glucose concentration.
  • the relationship between the current change and the blood glucose concentration is predefined and solidified within the chip of the microcontroller 13.
  • Step S34 the blood pressure sensor 14 measures the blood pressure value of the user, and sends the blood pressure value of the user to the microcontroller 13, and the microcontroller 13 corrects the blood glucose concentration value measurement according to the blood pressure value of the user. Error.
  • the microcontroller 13 uses the relationship function between the human blood pressure and the blood glucose to correct the error in the blood glucose concentration value measurement according to the blood pressure value of the user, so as to further improve the accuracy of detecting the blood glucose concentration.
  • the relationship between the blood pressure of the human body and blood sugar is predefined and solidified within the chip of the microcontroller 13.
  • Step S35 the wireless communication unit 15 transmits the corrected blood glucose concentration value to the mobile communication terminal 2 via the wireless network 4, so that the mobile communication terminal 2 dynamically displays the corrected blood glucose concentration value on the mobile communication terminal 2 On the display screen, users can dynamically understand their blood glucose concentration levels in real time, thus providing users with the convenience of monitoring their own changes in blood glucose concentration.
  • Step S36 the mobile communication terminal 2 transmits the corrected blood glucose concentration value to the medical monitoring platform 3 through the remote communication network 5, so that the doctor can dynamically and remotely track the user's blood glucose concentration in real time.
  • the level provides convenience for the doctor to track and monitor changes in the user's blood glucose levels.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A device, a system and a method for dynamic blood glucose monitoring, being applied to blood glucose monitoring for a diabetic patient. The dynamic blood glucose monitoring system comprises a dynamic blood glucose monitoring device (1), a mobile communication terminal (2) and a medical monitoring platform (3). The dynamic blood glucose monitoring device (1) is connected to the mobile communication terminal (2) by means of a wireless network (4), and the mobile communication terminal (2) is connected to the medical monitoring platform (3) by means of a remote communication network (5). The dynamic blood glucose monitoring device (1) dynamically detects, in real time, the blood glucose concentration values of a user, and sends the blood glucose concentration values of the user to the mobile communication terminal (2), and the blood glucose concentration values of the user are dynamically displayed on a display screen of the mobile communication terminal (2). The mobile communication terminal (2) transmits, by means of the remote communication network (5), the blood glucose concentration values of the user to the medical monitoring platform (3), so that a doctor can dynamically and remotely track, in real time, the blood glucose concentration level of the user. This invention provides convenience to both the user and the doctor for monitoring blood glucose data of the diabetic patient.

Description

动态血糖监护装置、系统及方法  Dynamic blood glucose monitoring device, system and method
技术领域Technical field
本发明涉及生命健康领域，尤其涉及一种用于糖尿病患者的动态血糖监护装置、系统及方法。The invention relates to the field of life health, and in particular to a dynamic blood glucose monitoring device, system and method for a diabetic patient.
背景技术Background technique
测量血中葡萄糖水平的血糖检测，应当对具有波动血糖水平的病人每天进行。而对严重糖尿病或其他专科疾病病人的诊断，一天内甚至要重复进行多次血糖检测，可能导致血糖检测准确度不高。虽然血糖检测在医院或其它医学研究机构中经常进行，但目前血糖监测均采用多次采血检测对血糖进行检测，而糖尿病患者一天需要3-6次检测才能满足需求，且采集的血糖数据多为本地存储，无法实现血糖数据与糖尿病医疗中心对接，无法实现医生对糖尿病患者的同步监护。因此，目前血糖监测系统不能够实现全天二十四小时不间断动态地监测糖尿病患者的血糖数据，以供医生实时地远程跟踪糖尿病患者的血糖浓度水平，这对医生和糖尿病患者在日常血糖检测与跟踪中非常不方便。Blood glucose testing to measure glucose levels in the blood should be performed daily for patients with fluctuating blood glucose levels. For the diagnosis of patients with severe diabetes or other specialist diseases, repeated blood glucose tests may be repeated within one day, which may result in low blood glucose detection accuracy. Although blood glucose testing is often performed in hospitals or other medical research institutions, blood glucose monitoring currently uses multiple blood tests to detect blood glucose, while diabetic patients need 3-6 tests a day to meet demand, and the collected blood glucose data are mostly Local storage, unable to achieve blood glucose data docking with the Diabetes Medical Center, can not achieve the doctor's simultaneous monitoring of diabetes patients. Therefore, the current blood glucose monitoring system cannot continuously monitor the blood glucose data of diabetic patients 24 hours a day, for the doctor to remotely track the blood glucose level of diabetic patients in real time, which is used for daily blood glucose testing by doctors and diabetic patients. Very inconvenient with tracking.
发明内容Summary of the invention
本发明的主要目的在于提供一种动态血糖监护装置、系统及方法，旨在解决现有血糖检测准确度不高以及无法实现医生实时断动态地监测糖尿病患者血糖数据的问题。The main object of the present invention is to provide a dynamic blood glucose monitoring device, system and method, which aim to solve the problem that the existing blood glucose detection accuracy is not high and the doctor cannot monitor the blood glucose data of the diabetic patient in real time.
为实现上述目的，本发明提供了一种动态血糖监护装置，包括采血探针、生化反应传感器、微控制器、血压传感器以及无线通信单元，其中：To achieve the above object, the present invention provides a dynamic blood glucose monitoring device comprising a blood sampling probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, wherein:
所述采血探针用于实时动态采集用户的血液并输出至生化反应传感器上，该生化反应传感器内包括血糖氧化酶试剂以及电路电阻；The blood collection probe is used for real-time dynamic collection of the user's blood and output to the biochemical reaction sensor, and the biochemical reaction sensor includes a blood glucose oxidase reagent and a circuit resistance;
所述生化反应传感器用于通过所述血糖氧化酶试剂与所述采血探针吸取的血液发生血糖氧化反应导致所述电路电阻的电阻值发生变化而输出变化的电流信号；The biochemical reaction sensor is configured to output a changing current signal by causing a blood glucose oxidation reaction of the blood glucose oxidase reagent and the blood drawn by the blood collection probe to cause a change in a resistance value of the circuit resistance;
所述微控制器用于根据所述生化反应传感器输出的电流信号计算出用户的血糖浓度值；The microcontroller is configured to calculate a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
所述血压感测器用于侦测出用户的血压值，并将所述用户的血压值发送至所述微控制器；The blood pressure sensor is configured to detect a blood pressure value of the user, and send the blood pressure value of the user to the microcontroller;
所述微控制器还用于根据用户的血压值校正所述血糖浓度值测量中的误差；The microcontroller is further configured to correct an error in the blood glucose concentration value measurement according to a blood pressure value of the user;
所述无线通信单元用于将校正的所述血糖浓度值发送至移动通信终端。The wireless communication unit is configured to transmit the corrected blood glucose concentration value to a mobile communication terminal.
优选的，所述动态血糖监护装置还包括一个连接至所述微控制器上的电源开关，用于开启或关闭所述动态血糖监护装置。Preferably, the dynamic blood glucose monitoring device further comprises a power switch connected to the microcontroller for turning the dynamic blood glucose monitoring device on or off.
优选的，所述动态血糖监护装置还包括一个连接至所述微控制器上的微型电池，该微型电池是一种低辐射、低功耗的可充电锂电池或者纽扣电池，用于对所述动态血糖监护装置提供工作电源。Preferably, the dynamic blood glucose monitoring device further includes a miniature battery connected to the microcontroller, the micro battery being a low-radiation, low-power rechargeable lithium battery or a button battery for The dynamic blood glucose monitoring device provides working power.
优选的，所述微控制器利用生化反应传感器输出电流变化与血糖浓度的关系函数来计算所述生化反应传感器输出的电流信号对应的血糖浓度值。Preferably, the microcontroller calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor by using a correlation function between the biochemical response sensor output current change and the blood glucose concentration.
优选的，所述微控制器利用人体血压与血糖的关系函数根据用户的血压值对所述血糖浓度值测量中的误差进行校正。Preferably, the microcontroller corrects an error in the measurement of the blood glucose concentration value according to a blood pressure value of the user by using a relationship function between blood pressure and blood sugar of the human body.
为实现上述目的，本发明还提供了一种动态血糖监护系统，该系统包括所述的动态血糖监护装置、移动通信终端以及医疗监护平台，所述动态血糖监护装置通过无线网络连接至所述移动通信终端，所述移动通信终端通过远程通信网络连接至所述医疗监护平台。To achieve the above object, the present invention also provides a dynamic blood glucose monitoring system including the dynamic blood glucose monitoring device, a mobile communication terminal, and a medical monitoring platform, the dynamic blood glucose monitoring device being connected to the mobile through a wireless network A communication terminal that is connected to the medical monitoring platform via a remote communication network.
优选的，所述移动通信终端将所述校正的血糖浓度值动态显示在所述移动通信终端的显示屏上，并将所述校正的血糖浓度值通过所述远程通信网络传输到所述医疗监护平台上，以供医生实时动态地远程跟踪用户的血糖浓度水平。Preferably, the mobile communication terminal dynamically displays the corrected blood glucose concentration value on a display screen of the mobile communication terminal, and transmits the corrected blood glucose concentration value to the medical monitoring through the remote communication network On the platform, the doctor can remotely and dynamically track the user's blood glucose level in real time.
优选的，本发明还提供了一种动态血糖监护方法，应用于动态血糖监护装置中，该装置包括采血探针、生化反应传感器、微控制器、血压传感器以及无线通信单元，所述动态血糖监护方法包括：Preferably, the present invention further provides a dynamic blood glucose monitoring method for use in a dynamic blood glucose monitoring device, the device comprising a blood collection probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, the dynamic blood glucose monitoring Methods include:
所述采血探针实时动态采集用户的血液并输出至生化反应传感器上；The blood sampling probe dynamically collects the user's blood in real time and outputs it to the biochemical reaction sensor;
所述生化反应传感器内的血糖氧化酶试剂与所述采血探针吸取的血液发生血糖氧化反应导致所述生化反应传感器内的电路电阻的电阻值发生变化而输出变化的电流信号；The blood glucose oxidase reagent in the biochemical reaction sensor and the blood drawn by the blood sampling probe cause a blood glucose oxidation reaction to cause a change in a resistance value of a circuit resistance in the biochemical reaction sensor to output a changed current signal;
所述微控制器根据所述生化反应传感器输出的电流信号计算出用户的血糖浓度值；The microcontroller calculates a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
所述血压感测器侦测出用户的血压值，并将所述用户的血压值发送至所述微控制器；The blood pressure sensor detects a blood pressure value of the user, and sends the blood pressure value of the user to the microcontroller;
所述微控制器根据用户的血压值校正所述血糖浓度值测量中的误差；以及The microcontroller corrects an error in the measurement of the blood glucose concentration value according to a blood pressure value of the user;
所述无线通信单元将所述校正的血糖浓度值发送至移动通信终端。The wireless communication unit transmits the corrected blood glucose concentration value to the mobile communication terminal.
优选的，所述动态血糖监护装置通过无线网络连接至所述移动通信终端，所述移动通信终端通过远程通信网络连接至所述医疗监护平台。Preferably, the dynamic blood glucose monitoring device is connected to the mobile communication terminal through a wireless network, and the mobile communication terminal is connected to the medical monitoring platform through a remote communication network.
优选的，所述动态血糖监护方法还包括步骤：Preferably, the dynamic blood glucose monitoring method further comprises the steps of:
将所述校正的血糖浓度值动态显示在所述移动通信终端的显示屏上；Displaying the corrected blood glucose concentration value dynamically on a display screen of the mobile communication terminal;
通过所述移动通信终端将所述校正的血糖浓度值通过所述远程通信网络传输到所述医疗监护平台上，以供医生实时动态地远程跟踪用户的血糖浓度水平。The corrected blood glucose concentration value is transmitted to the medical monitoring platform through the remote communication network by the mobile communication terminal, so that the doctor can dynamically and dynamically track the user's blood glucose concentration level in real time.
相较于现有技术，本发明所述动态血糖监护装置、系统及方法，应用于糖尿病患者的动态血糖监测中，能够提高血糖浓度监测的准确性并实现全天二十四小时不间断动态地监测糖尿病患者的血糖数据，以供医生实时地远程跟踪用户的血糖浓度水平，为糖尿病患者和医生双方监测血糖数据提供了极大的方便。Compared with the prior art, the dynamic blood glucose monitoring device, system and method of the present invention are applied to dynamic blood glucose monitoring of diabetic patients, can improve the accuracy of blood glucose concentration monitoring and realize uninterrupted dynamics 24 hours a day. Monitoring the blood glucose data of diabetic patients for the doctor to remotely track the user's blood glucose concentration level in real time, which provides great convenience for both diabetic patients and doctors to monitor blood glucose data.
附图说明DRAWINGS
图1是本发明动态血糖监护系统优选实施例的系统架构图；1 is a system architecture diagram of a preferred embodiment of the dynamic blood glucose monitoring system of the present invention;
图2是本发明动态血糖监护装置优选实施例的内部结构图；Figure 2 is a diagram showing the internal structure of a preferred embodiment of the dynamic blood glucose monitoring device of the present invention;
图3是本发明动态血糖监护方法优选实施例的流程图。3 is a flow chart of a preferred embodiment of the dynamic blood glucose monitoring method of the present invention.
本发明目的实现、功能特点及优点将结合实施例，参照附图做进一步说明。The object, features, and advantages of the invention will be further described in conjunction with the embodiments.
具体实施方式detailed description
为更进一步阐述本发明为达成上述目的所采取的技术手段及功效，以下结合附图及较佳实施例，对本发明的具体实施方式、结构、特征及其功效进行详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。The specific embodiments, structures, features and functions of the present invention are described in detail below with reference to the accompanying drawings and preferred embodiments. It is understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
为实现本发明目的，本发明提供了一种动态血糖监护系统，能够提高血糖浓度监测的准确性并实现全天二十四小时不间断动态地监测糖尿病患者的血糖数据，以供医生实时地远程跟踪用户的血糖浓度水平，为糖尿病患者和医生双方监测的血糖数据提供了极大的方便。In order to achieve the object of the present invention, the present invention provides a dynamic blood glucose monitoring system capable of improving the accuracy of blood glucose concentration monitoring and continuously monitoring blood glucose data of diabetic patients 24 hours a day for a doctor to remotely operate in real time. Tracking the user's blood glucose level provides great convenience for blood glucose data monitored by both diabetics and doctors.
如图1所示，图1是本发明动态血糖监护系统优选实施例的系统架构图。在本实施例中，所述动态血糖监护系统包括动态血糖监护装置1、移动通信终端2以及医疗监护平台3。所述动态血糖监护装置1通过无线网络4连接至所述移动通信终端2，该移动通信终端2通过远程通信网络5连接至所述医疗监护平台3。所述无线网络4包括但不仅限于，蓝牙、WiFi等无线传输网络，所述远程通信网络5包括但不仅限于，GSM网络、GPRS网络、CDMA等无线传输网络。所述动态血糖监护装置1为一种佩戴在用户（例如糖尿病患者）身上的可穿戴式动态血糖监护装置，可以集成在通用的腕表、手环等可穿戴设备上。所述移动通信终端2包括，但不仅限于，手机、个人数字辅助设备（PDA），掌上电脑等无线通讯设备。所述医疗监护平台3为一种设置在糖尿病医疗监测中心的远程监控设备或服务器等。在本实施例中，所述用户是指糖尿病患者或者其它需要实时对血糖水平进行动态监控的病人。As shown in FIG. 1, FIG. 1 is a system architecture diagram of a preferred embodiment of the dynamic blood glucose monitoring system of the present invention. In this embodiment, the dynamic blood glucose monitoring system includes a dynamic blood glucose monitoring device 1, a mobile communication terminal 2, and a medical monitoring platform 3. The dynamic blood glucose monitoring device 1 is connected to the mobile communication terminal 2 via a wireless network 4, which is connected to the medical monitoring platform 3 via a remote communication network 5. The wireless network 4 includes, but is not limited to, a wireless transmission network such as Bluetooth, WiFi, etc., and the remote communication network 5 includes, but is not limited to, a wireless transmission network such as a GSM network, a GPRS network, or a CDMA. The dynamic blood glucose monitoring device 1 is a wearable dynamic blood glucose monitoring device worn on a user (for example, a diabetic patient), and can be integrated on a wearable device such as a universal wristwatch or a wristband. The mobile communication terminal 2 includes, but is not limited to, a wireless communication device such as a mobile phone, a personal digital assistant (PDA), a palmtop computer, or the like. The medical monitoring platform 3 is a remote monitoring device or server or the like disposed at the diabetes medical monitoring center. In the present embodiment, the user refers to a diabetic patient or other patient who needs to dynamically monitor blood glucose levels in real time.
在本实施例中，所述动态血糖监护装置1用于全天24小时实时动态地采集用户的血糖浓度值，并将所述用户的血糖浓度值通过无线网络4发送至所述移动通信终端2上进行显示，让用户动态了解自己的血糖浓度水平。所述移动通信终端2通过远程通信网络5将所述用户的血糖浓度值传输到设置在糖尿病医疗监测中心的医疗监护平台3上，以供医生实时地远程跟踪用户的血糖浓度水平。In this embodiment, the dynamic blood glucose monitoring device 1 is configured to dynamically collect the blood glucose concentration value of the user in real time 24 hours a day, and send the blood glucose concentration value of the user to the mobile communication terminal 2 through the wireless network 4 . Displayed on the screen to let users dynamically understand their blood glucose level. The mobile communication terminal 2 transmits the blood glucose concentration value of the user to the medical monitoring platform 3 set in the diabetes medical monitoring center through the remote communication network 5, so that the doctor can remotely track the blood sugar concentration level of the user in real time.
如图2所示，图2是本发明动态血糖监护装置优选实施例的内部结构图。在本实施例中，所述动态血糖监护装置1包括，但不仅限于，电源开关10、采血探针11、生化反应传感器12、微控制器13、血压传感器14以及无线通信单元15。所述电源开关10、采血探针11、生化反应传感器12、血压传感器14和无线通信单元15分别电气连接至微控制器13上，所述采血探针11还连接至所述生化反应传感器12上。As shown in Fig. 2, Fig. 2 is an internal structural view of a preferred embodiment of the dynamic blood glucose monitoring device of the present invention. In the present embodiment, the dynamic blood glucose monitoring device 1 includes, but is not limited to, a power switch 10, a blood collection probe 11, a biochemical reaction sensor 12, a microcontroller 13, a blood pressure sensor 14, and a wireless communication unit 15. The power switch 10, the blood collection probe 11, the biochemical reaction sensor 12, the blood pressure sensor 14, and the wireless communication unit 15 are electrically connected to the microcontroller 13, respectively, and the blood collection probe 11 is further connected to the biochemical reaction sensor 12. .
所述电源开关10用于开启或关闭所述动态血糖监护装置，当电源开关10被开启时，所述采血探针11用于实时动态采集用户的血液，并将用户的血液发送至所述生化反应传感器12。例如，当所述动态血糖监护装置1佩戴在用户的手腕上时，所述采血探针11自动刺入用户手腕的皮下组织并从手腕部位吸取血液。所述采血探针11为一种带有微孔的细小探针，当刺入用户的皮下组织时，并不会对用户产生明显的疼痛感，因而可以减少对用户采血时的疼痛。此外，所述用户的血液也可以由采血探针11从外部血液存储管中实时吸取，该血液存储管中存储有用户待检测的血液并实时动态地更新血液。The power switch 10 is configured to turn on or off the dynamic blood glucose monitoring device. When the power switch 10 is turned on, the blood collection probe 11 is configured to dynamically collect the user's blood in real time, and send the user's blood to the biochemical. Reaction sensor 12. For example, when the dynamic blood glucose monitoring device 1 is worn on a wrist of a user, the blood collection probe 11 automatically penetrates the subcutaneous tissue of the user's wrist and draws blood from the wrist. The blood collection probe 11 is a small probe with micropores, which does not cause a significant pain to the user when piercing the subcutaneous tissue of the user, thereby reducing pain when the user collects blood. In addition, the blood of the user can also be sucked from the external blood storage tube by the blood collection probe 11 in real time, and the blood storage tube stores the blood to be detected by the user and dynamically updates the blood in real time.
所述生化反应传感器12内包括血糖氧化酶试剂以及电路电阻，当所述生化反应传感器12从采血探针11获取所采集到的血液时，所述生化反应传感器12内的血糖氧化酶试剂与所述血液发生血糖氧化反应导致所述电路电阻的电阻值发生变化而输出变化的电流信号，并将所述电流信号输出至所述微控制器13上。The biochemical reaction sensor 12 includes a blood glucose oxidase reagent and a circuit resistance. When the biochemical reaction sensor 12 acquires the collected blood from the blood collection probe 11, the blood glucose oxidase reagent and the biochemical reaction sensor 12 The blood glucose oxidation reaction causes a change in the resistance value of the circuit resistance to output a varying current signal, and outputs the current signal to the microcontroller 13.
所述微控制器13是一种微处理器、数据处理芯片、或者具有数据处理功能的信息处理单元。所述微控制器13用于根据所述生化反应传感器12输出的电流信号计算出用户的血糖浓度值。在本实施例中，所述微控制器13利用所述生化反应传感器12输出电流变化与血糖浓度的关系函数来计算所述生化反应传感器12输出的电流信号对应的血糖浓度值。所述电流变化与血糖浓度的关系函数预先定义并固化在所述微控制器13的芯片内。The microcontroller 13 is a microprocessor, a data processing chip, or an information processing unit having data processing functions. The microcontroller 13 is configured to calculate a blood glucose concentration value of the user according to the current signal output by the biochemical reaction sensor 12. In the present embodiment, the microcontroller 13 calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor 12 by using the biochemical response sensor 12 to output a relationship function between the current change and the blood glucose concentration. The relationship between the current change and the blood glucose concentration is predefined and solidified within the chip of the microcontroller 13.
所述血压传感器14为一种用于侦测人体腕动脉脉搏压力值的微型血压传感器芯片，将其紧贴人体腕动脉旁边能够对人体血压进行检测。在本实施例中，所述血压感测器14用于从用户的腕动脉侦测出用户的血压值，并将所述用户的血压值发送至所述微控制器13，该微控制器13根据用户的血压值校正所述血糖浓度值测量中的误差。在本实施例中，所述微控制器13利用人体血压与血糖的关系函数根据用户的血压值对所述血糖浓度值测量中的误差进行校正，以便进一步地提高检测血糖浓度的准确性。所述人体血压与血糖的关系函数预先定义并固化在所述微控制器13的芯片内。The blood pressure sensor 14 is a miniature blood pressure sensor chip for detecting the pulse pressure value of the human wrist artery, and is closely attached to the wrist artery of the human body to detect the blood pressure of the human body. In this embodiment, the blood pressure sensor 14 is configured to detect a blood pressure value of the user from the wrist artery of the user, and send the blood pressure value of the user to the microcontroller 13, the microcontroller 13 The error in the measurement of the blood glucose concentration value is corrected based on the blood pressure value of the user. In the present embodiment, the microcontroller 13 uses the relationship function between the human blood pressure and the blood glucose to correct the error in the blood glucose concentration value measurement according to the blood pressure value of the user, so as to further improve the accuracy of detecting the blood glucose concentration. The relationship between the blood pressure of the human body and blood sugar is predefined and solidified within the chip of the microcontroller 13.
所述无线通信单元15为一种支持蓝牙、WiFi等无线传输网络的无线通讯接口，用于将所述用户的血糖浓度值通过所述无线网络4发送至移动通信终端2上，以供移动通信终端2将所述用户的血糖浓度值动态显示在该移动通信终端2的显示屏上，让用户实时地动态了解自己的血糖浓度水平。所述移动通信终端2还可以通过所述远程通信网络5将所述用户的血糖浓度值传输到所述医疗监护平台3上，以供医生实时地远程跟踪用户的血糖浓度水平，从而为用户和医生双方动态监护血糖情况提供了方便。The wireless communication unit 15 is a wireless communication interface supporting a wireless transmission network such as Bluetooth or WiFi, and is configured to send the blood glucose concentration value of the user to the mobile communication terminal 2 through the wireless network 4 for mobile communication. The terminal 2 dynamically displays the blood glucose concentration value of the user on the display screen of the mobile communication terminal 2, so that the user dynamically knows his blood glucose concentration level in real time. The mobile communication terminal 2 can also transmit the blood glucose concentration value of the user to the medical monitoring platform 3 through the remote communication network 5, so that the doctor can remotely track the blood glucose concentration level of the user in real time, thereby serving the user and It is convenient for both doctors to dynamically monitor blood sugar levels.
在本实施例中，所述动态血糖监护装置1还包括一个连接至所述微控制器13上的微型电池16，用于对所述动态血糖监护装置1提供工作电源。该微型电池16是一种低辐射、低功耗的可充电锂电池或者纽扣电池，其不会对使用者的健康带来影响。In the present embodiment, the dynamic blood glucose monitoring device 1 further includes a micro battery 16 connected to the microcontroller 13 for providing operating power to the dynamic blood glucose monitoring device 1. The miniature battery 16 is a low-radiation, low-power rechargeable lithium battery or button battery that does not affect the health of the user.
为实现本发明目的，本发明还提供了一种动态血糖监护方法，能够提高血糖浓度监测的准确性并实现全天二十四小时不间断动态地监测糖尿病患者的血糖数据，以供医生实时地远程跟踪用户的血糖浓度水平，为糖尿病患者和医生双方监测血糖数据提供了极大的方便。In order to achieve the object of the present invention, the present invention also provides a dynamic blood glucose monitoring method, which can improve the accuracy of blood glucose concentration monitoring and realize continuous monitoring of blood glucose data of diabetic patients 24 hours a day for doctors in real time. Remotely tracking the user's blood glucose level provides great convenience for both diabetics and doctors to monitor blood glucose data.
如图3所示，图3是本发明动态血糖监护装置动态血糖监护方法优选实施例的流程图。在本较佳实施例中，所述的动态血糖监护方法应用于动态血糖监护装置1、移动通信终端2以及医疗监护平台3中，该方法包括如下步骤S31至步骤S36。As shown in FIG. 3, FIG. 3 is a flow chart of a preferred embodiment of the dynamic blood glucose monitoring method of the dynamic blood glucose monitoring device of the present invention. In the preferred embodiment, the dynamic blood glucose monitoring method is applied to the dynamic blood glucose monitoring device 1, the mobile communication terminal 2, and the medical monitoring platform 3, and the method includes the following steps S31 to S36.
步骤S31，采血探针11实时动态采集用户的血液并输出至生化反应传感器12上。具体地，当用户开启动态血糖监护装置1的电源开关10时，微控制器13驱动动态血糖监护装置1上的采血探针11自动用户的血液并输出至生化反应传感器12上。例如，当所述动态血糖监护装置1佩戴在用户的手腕上时，所述微控制器13控制采血探针11自动刺入用户手腕的皮下组织并从手腕部位吸取血液。此外，所述用户的血液也可以由采血探针11从外部血液存储管中实时吸取，该血液存储管中存储有用户待检测的血液并实时动态地更新血液。In step S31, the blood collection probe 11 dynamically collects the blood of the user in real time and outputs it to the biochemical reaction sensor 12. Specifically, when the user turns on the power switch 10 of the dynamic blood glucose monitoring device 1, the microcontroller 13 drives the blood of the automatic blood collection probe 11 on the dynamic blood glucose monitoring device 1 and outputs it to the biochemical reaction sensor 12. For example, when the dynamic blood glucose monitoring device 1 is worn on the wrist of the user, the microcontroller 13 controls the blood collection probe 11 to automatically puncture the subcutaneous tissue of the user's wrist and draw blood from the wrist. In addition, the blood of the user can also be sucked from the external blood storage tube by the blood collection probe 11 in real time, and the blood storage tube stores the blood to be detected by the user and dynamically updates the blood in real time.
步骤S32，生化反应传感器12内的血糖氧化酶试剂与所述采血探针吸取的血液发生血糖氧化反应导致生化反应传感器12内的电路电阻的电阻值发生变化而输出变化的电流信号，并将所述电流信号输出至微控制器13上。Step S32, the blood glucose oxidase reagent in the biochemical reaction sensor 12 and the blood drawn by the blood sampling probe cause a blood glucose oxidation reaction to cause a change in the resistance value of the circuit resistance in the biochemical reaction sensor 12 to output a changed current signal, and The current signal is output to the microcontroller 13.
步骤S33，微控制器13根据所述生化反应传感器12输出的电流信号计算出用户的血糖浓度值。在本实施例中，所述微控制器13利用所述生化反应传感器12输出电流变化与血糖浓度的关系函数来计算所述生化反应传感器12输出的电流信号对应的血糖浓度值。所述电流变化与血糖浓度的关系函数预先定义并固化在所述微控制器13的芯片内。In step S33, the microcontroller 13 calculates the blood glucose concentration value of the user based on the current signal output by the biochemical reaction sensor 12. In the present embodiment, the microcontroller 13 calculates a blood glucose concentration value corresponding to the current signal output by the biochemical reaction sensor 12 by using the biochemical response sensor 12 to output a relationship function between the current change and the blood glucose concentration. The relationship between the current change and the blood glucose concentration is predefined and solidified within the chip of the microcontroller 13.
步骤S34，血压感测器14测出用户的血压值，并将所述用户的血压值发送至所述微控制器13，该微控制器13根据用户的血压值校正所述血糖浓度值测量中的误差。在本实施例中，所述微控制器13利用人体血压与血糖的关系函数根据用户的血压值对所述血糖浓度值测量中的误差进行校正，以便进一步地提高检测血糖浓度的准确性。所述人体血压与血糖的关系函数预先定义并固化在所述微控制器13的芯片内。Step S34, the blood pressure sensor 14 measures the blood pressure value of the user, and sends the blood pressure value of the user to the microcontroller 13, and the microcontroller 13 corrects the blood glucose concentration value measurement according to the blood pressure value of the user. Error. In the present embodiment, the microcontroller 13 uses the relationship function between the human blood pressure and the blood glucose to correct the error in the blood glucose concentration value measurement according to the blood pressure value of the user, so as to further improve the accuracy of detecting the blood glucose concentration. The relationship between the blood pressure of the human body and blood sugar is predefined and solidified within the chip of the microcontroller 13.
步骤S35，无线通信单元15将所述校正的血糖浓度值通过无线网络4发送至移动通信终端2上，以供移动通信终端2将所述校正的血糖浓度值动态显示在该移动通信终端2的显示屏上，让用户实时地动态了解自己的血糖浓度水平，从而为用户监控自身的血糖浓度变化提供了方便。Step S35, the wireless communication unit 15 transmits the corrected blood glucose concentration value to the mobile communication terminal 2 via the wireless network 4, so that the mobile communication terminal 2 dynamically displays the corrected blood glucose concentration value on the mobile communication terminal 2 On the display screen, users can dynamically understand their blood glucose concentration levels in real time, thus providing users with the convenience of monitoring their own changes in blood glucose concentration.
步骤S36，移动通信终端2将所述校正的血糖浓度值通过远程通信网络5将所述校正的血糖浓度值传输到所述医疗监护平台3上，以供医生实时动态地远程跟踪用户的血糖浓度水平，从而为医生跟踪并监护用户的血糖浓度变化提供了方便。Step S36, the mobile communication terminal 2 transmits the corrected blood glucose concentration value to the medical monitoring platform 3 through the remote communication network 5, so that the doctor can dynamically and remotely track the user's blood glucose concentration in real time. The level provides convenience for the doctor to track and monitor changes in the user's blood glucose levels.
以上仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书及附图内容所作的等效结构或等效功能变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。The above is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and equivalent structural or equivalent functional changes made by the description of the present invention and the accompanying drawings may be directly or indirectly applied to other related technical fields. The same is included in the scope of patent protection of the present invention.

Claims (10)

  1. 一种动态血糖监护装置，其特征在于，所述动态血糖监护装置包括采血探针、生化反应传感器、微控制器、血压传感器以及无线通信单元，其中： A dynamic blood glucose monitoring device, comprising: a blood collection probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, wherein:
    所述采血探针用于实时动态采集用户的血液并输出至生化反应传感器上，该生化反应传感器内包括血糖氧化酶试剂以及电路电阻；The blood collection probe is used for real-time dynamic collection of the user's blood and output to the biochemical reaction sensor, and the biochemical reaction sensor includes a blood glucose oxidase reagent and a circuit resistance;
    所述生化反应传感器用于通过所述血糖氧化酶试剂与所述采血探针吸取的血液发生血糖氧化反应导致所述电路电阻的电阻值发生变化而输出变化的电流信号；The biochemical reaction sensor is configured to output a changing current signal by causing a blood glucose oxidation reaction of the blood glucose oxidase reagent and the blood drawn by the blood collection probe to cause a change in a resistance value of the circuit resistance;
    所述微控制器用于根据所述生化反应传感器输出的电流信号计算出用户的血糖浓度值；The microcontroller is configured to calculate a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
    所述血压感测器用于侦测出用户的血压值，并将所述用户的血压值发送至所述微控制器；The blood pressure sensor is configured to detect a blood pressure value of the user, and send the blood pressure value of the user to the microcontroller;
    所述微控制器还用于根据用户的血压值校正所述血糖浓度值测量中的误差；以及The microcontroller is further configured to correct an error in the blood glucose concentration value measurement according to a blood pressure value of the user;
    所述无线通信单元用于将校正的所述血糖浓度值发送至移动通信终端。 The wireless communication unit is configured to transmit the corrected blood glucose concentration value to a mobile communication terminal.
  2. 如权利要求1所述的动态血糖监护装置，其特征在于，该动态血糖监护装置还包括一个连接至所述微控制器上的电源开关，用于开启或关闭所述动态血糖监护装置。The dynamic blood glucose monitoring device of claim 1 further comprising a power switch coupled to said microcontroller for turning said dynamic blood glucose monitoring device on or off.
  3. 如权利要求2所述的动态血糖监护装置，其特征在于，该动态血糖监护装置还包括一个连接至所述微控制器上的微型电池，该微型电池是一种低辐射、低功耗的可充电锂电池或者纽扣电池，用于对所述动态血糖监护装置提供工作电源。The dynamic blood glucose monitoring device according to claim 2, wherein the dynamic blood glucose monitoring device further comprises a micro battery connected to the microcontroller, the micro battery being a low radiation, low power consumption A rechargeable lithium battery or a button battery is used to provide operating power to the dynamic blood glucose monitoring device.
  4. 如权利要求1所述的动态血糖监护装置，其特征在于，所述微控制器利用所述生化反应传感器输出电流变化与血糖浓度的关系函数来计算所述生化反应传感器输出的电流信号对应的血糖浓度值。The dynamic blood glucose monitoring device according to claim 1, wherein the microcontroller calculates a blood glucose corresponding to the current signal output by the biochemical reaction sensor by using a correlation function between the output current change and the blood glucose concentration of the biochemical reaction sensor. Concentration value.
  5. 如权利要求1所述的动态血糖监护装置，其特征在于，所述微控制器利用人体血压与血糖的关系函数根据用户的血压值对所述血糖浓度值测量中的误差进行校正。The dynamic blood glucose monitoring device according to claim 1, wherein said microcontroller corrects an error in said blood glucose concentration value measurement based on a blood pressure value of the user using a relationship function between blood pressure and blood sugar of the human body.
  6. 一种包括如权利要求1所述的动态血糖监护装置的动态血糖监护系统，其特征在于，该动态血糖监护系统还包括移动通信终端以及医疗监护平台，所述动态血糖监护装置通过无线网络连接至所述移动通信终端，所述移动通信终端通过远程通信网络连接至所述医疗监护平台。 A dynamic blood glucose monitoring system comprising the dynamic blood glucose monitoring device according to claim 1, wherein the dynamic blood glucose monitoring system further comprises a mobile communication terminal and a medical monitoring platform, wherein the dynamic blood glucose monitoring device is connected to the wireless network to The mobile communication terminal is connected to the medical monitoring platform via a remote communication network.
  7. 如权利要求6所述的动态血糖监护系统，其特征在于，所述移动通信终端将所述校正的血糖浓度值动态显示在所述移动通信终端的显示屏上，并将所述用户的血糖浓度值通过所述远程通信网络传输到所述医疗监护平台上，以供医生实时动态地远程跟踪用户的血糖浓度水平。 A dynamic blood glucose monitoring system according to claim 6, wherein said mobile communication terminal dynamically displays said corrected blood glucose concentration value on a display screen of said mobile communication terminal, and sets said user's blood glucose concentration The value is transmitted to the medical monitoring platform through the remote communication network for the doctor to dynamically and dynamically track the user's blood glucose concentration level in real time.
  8. 一种动态血糖监护方法，应用于动态血糖监护装置中，其特征在于，所述动态血糖监护装置包括采血探针、生化反应传感器、微控制器、血压传感器以及无线通信单元，所述动态血糖监护方法包括步骤：A dynamic blood glucose monitoring method is applied to a dynamic blood glucose monitoring device, wherein the dynamic blood glucose monitoring device comprises a blood sampling probe, a biochemical reaction sensor, a microcontroller, a blood pressure sensor, and a wireless communication unit, and the dynamic blood glucose monitoring device The method includes the steps of:
    所述采血探针实时动态采集血液并输出至生化反应传感器上；The blood sampling probe dynamically collects blood in real time and outputs it to a biochemical reaction sensor;
    所述生化反应传感器内的血糖氧化酶试剂与所述采血探针吸取的血液发生血糖氧化反应导致所述生化反应传感器内的电路电阻的电阻值发生变化而输出变化的电流信号；The blood glucose oxidase reagent in the biochemical reaction sensor and the blood drawn by the blood sampling probe cause a blood glucose oxidation reaction to cause a change in a resistance value of a circuit resistance in the biochemical reaction sensor to output a changed current signal;
    所述微控制器根据所述生化反应传感器输出的电流信号计算出用户的血糖浓度值；The microcontroller calculates a blood glucose concentration value of the user according to a current signal output by the biochemical reaction sensor;
    所述血压感测器侦测出用户的血压值，并将所述用户的血压值发送至所述微控制器；The blood pressure sensor detects a blood pressure value of the user, and sends the blood pressure value of the user to the microcontroller;
    所述微控制器根据用户的血压值校正所述血糖浓度值测量中的误差；The microcontroller corrects an error in the measurement of the blood glucose concentration value according to a blood pressure value of the user;
    所述无线通信单元将所述校正的血糖浓度值发送至移动通信终端。The wireless communication unit transmits the corrected blood glucose concentration value to the mobile communication terminal.
  9. 如权利要求8所述的动态血糖监护方法，其特征在于，所述动态血糖监护装置通过无线网络连接至所述移动通信终端，所述移动通信终端通过远程通信网络连接至所述医疗监护平台。The dynamic blood glucose monitoring method according to claim 8, wherein said dynamic blood glucose monitoring device is connected to said mobile communication terminal via a wireless network, said mobile communication terminal being connected to said medical monitoring platform via a remote communication network.
  10. 如权利要求9所述的动态血糖监护方法，其特征在于，该方法还包括步骤： The dynamic blood glucose monitoring method according to claim 9, wherein the method further comprises the steps of:
    将所述校正的血糖浓度值动态显示在所述移动通信终端的显示屏上；Displaying the corrected blood glucose concentration value dynamically on a display screen of the mobile communication terminal;
    通过所述移动通信终端将所述校正的血糖浓度值通过所述远程通信网络传输到所述医疗监护平台上，以供医生实时动态地远程跟踪用户的血糖浓度水平。 The corrected blood glucose concentration value is transmitted to the medical monitoring platform through the remote communication network by the mobile communication terminal, so that the doctor can dynamically and dynamically track the user's blood glucose concentration level in real time.
PCT/CN2016/071798 2015-12-05 2016-01-23 Dynamic blood glucose monitoring device, system and method WO2017092169A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510888836.4 2015-12-05
CN201510888836.4A CN105496422A (en) 2015-12-05 2015-12-05 Dynamic blood glucose monitoring device, system and method

Publications (1)

Publication Number Publication Date
WO2017092169A1 true WO2017092169A1 (en) 2017-06-08

Family

ID=55704994

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2016/071798 WO2017092169A1 (en) 2015-12-05 2016-01-23 Dynamic blood glucose monitoring device, system and method

Country Status (2)

Country Link
CN (1) CN105496422A (en)
WO (1) WO2017092169A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106770526A (en) * 2017-01-11 2017-05-31 朱斌 A kind of blood sugar test method
CN107743256A (en) * 2017-10-31 2018-02-27 广东九联科技股份有限公司 A kind of set top box and its method of testing with blood sugar test
CN109360665A (en) * 2018-08-30 2019-02-19 中南大学 A kind of classroom total management system for childhood and adolescence diabetes control
CN113812945B (en) * 2021-07-29 2022-07-19 重庆市人民医院 Tracking type dynamic blood sugar detector

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060226991A1 (en) * 2005-04-06 2006-10-12 Rivas Victor A Vital signals and glucose monitoring personal wireless system
CN101803912A (en) * 2010-03-01 2010-08-18 北京康瑞华泰医药科技有限公司 Medical detector capable of wirelessly transmitting information
US20100324398A1 (en) * 2007-05-11 2010-12-23 Jung Tzyy-Ping Non-invasive characterization of a physiological parameter
CN102012390A (en) * 2010-11-15 2011-04-13 普林斯顿医疗科技（珠海）有限公司 Wireless multifunctional continuous glucose monitoring system
WO2013012862A1 (en) * 2011-07-18 2013-01-24 Nanoviova Llc Real-time health data analysis using a mobile device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060226991A1 (en) * 2005-04-06 2006-10-12 Rivas Victor A Vital signals and glucose monitoring personal wireless system
US20100324398A1 (en) * 2007-05-11 2010-12-23 Jung Tzyy-Ping Non-invasive characterization of a physiological parameter
CN101803912A (en) * 2010-03-01 2010-08-18 北京康瑞华泰医药科技有限公司 Medical detector capable of wirelessly transmitting information
CN102012390A (en) * 2010-11-15 2011-04-13 普林斯顿医疗科技（珠海）有限公司 Wireless multifunctional continuous glucose monitoring system
WO2013012862A1 (en) * 2011-07-18 2013-01-24 Nanoviova Llc Real-time health data analysis using a mobile device

Also Published As

Publication number Publication date
CN105496422A (en) 2016-04-20

Similar Documents

Publication Publication Date Title
JP5567723B2 (en) Data collection system on two wrists
Fensli et al. A wearable ECG-recording system for continuous arrhythmia monitoring in a wireless tele-home-care situation
CN201993766U (en) Portable remote life multi-parameter monitoring terminal and constructed remote monitoring system
WO2017166818A1 (en) Wearable 12-lead remote electrocardiogram monitoring device, and system and method for applying same
CN102117384A (en) Portable remote life multi-parameter monitoring terminal and constructed remote monitoring system
CN101791214A (en) Community health-oriented portable monitoring system
CN104181809B (en) Intelligent wristwatch integrating pedometer function, electrocardiogram function and blood oxygen function
WO2017092169A1 (en) Dynamic blood glucose monitoring device, system and method
CN205433706U (en) Noninvasive glucose monitoring based on finger detects
CN102012390A (en) Wireless multifunctional continuous glucose monitoring system
Lee et al. A mobile-care system integrated with Bluetooth blood pressure and pulse monitor, and cellular phone
CN202075262U (en) Wireless multifunctional continuous glucose monitoring system
Manivannan et al. Evaluation of a behind-the-ear ECG device for smartphone based integrated multiple smart sensor system in health applications
CN201879675U (en) Hand-holding wireless health monitor
CN203885485U (en) Multifunctional health detector
CN109009019A (en) Multi-parameter physiological detector
CN205234512U (en) Wearable high accuracy blood sugar check out test set
Meng et al. Wearable systems and applications for healthcare
CN211022740U (en) Wireless heart sound signal acquisition device
Yang et al. Research of portable community-oriented health monitoring terminal
CN212008332U (en) Blood sugar and blood fat minimally invasive monitoring device and system
Yang et al. Research of portable ECG monitoring device
CN206044626U (en) A kind of health of heart inspection system
CN1935087A (en) Cardio current graphy utilizing mobile communication terminal
CN206560432U (en) It is established in the Sleep Apnea monitoring analysis system of Internet of Things

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16869483

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 16869483

Country of ref document: EP

Kind code of ref document: A1