WO2017087912A3 - Biocapteurs ratiométriques et transfert d'énergie par résonance de förster non modulé géométriquement - Google Patents

Biocapteurs ratiométriques et transfert d'énergie par résonance de förster non modulé géométriquement Download PDF

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Publication number
WO2017087912A3
WO2017087912A3 PCT/US2016/062958 US2016062958W WO2017087912A3 WO 2017087912 A3 WO2017087912 A3 WO 2017087912A3 US 2016062958 W US2016062958 W US 2016062958W WO 2017087912 A3 WO2017087912 A3 WO 2017087912A3
Authority
WO
WIPO (PCT)
Prior art keywords
biosensors
ratiometric
fret
geometrically modulated
ratiometric biosensors
Prior art date
Application number
PCT/US2016/062958
Other languages
English (en)
Other versions
WO2017087912A2 (fr
Inventor
Homme W. Hellinga
Malin J. Allert
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Priority to CA3005883A priority Critical patent/CA3005883A1/fr
Priority to EP16867307.7A priority patent/EP3377610A4/fr
Publication of WO2017087912A2 publication Critical patent/WO2017087912A2/fr
Publication of WO2017087912A3 publication Critical patent/WO2017087912A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Optical Transform (AREA)

Abstract

La présente invention concerne des biocapteurs ratiométriques ainsi que des compositions, des dispositifs et des procédés faisant intervenir lesdits biocapteurs.
PCT/US2016/062958 2015-11-20 2016-11-19 Biocapteurs ratiométriques et transfert d'énergie par résonance de förster non modulé géométriquement WO2017087912A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA3005883A CA3005883A1 (fr) 2015-11-20 2016-11-19 Biocapteurs ratiometriques et transfert d'energie par resonance de forster non module geometriquement
EP16867307.7A EP3377610A4 (fr) 2015-11-20 2016-11-19 Biocapteurs ratiométriques et transfert d'énergie par résonance de förster non modulé géométriquement

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562257863P 2015-11-20 2015-11-20
US201562257796P 2015-11-20 2015-11-20
US201562257859P 2015-11-20 2015-11-20
US201562257850P 2015-11-20 2015-11-20
US62/257,850 2015-11-20
US62/257,863 2015-11-20
US62/257,796 2015-11-20
US62/257,859 2015-11-20

Publications (2)

Publication Number Publication Date
WO2017087912A2 WO2017087912A2 (fr) 2017-05-26
WO2017087912A3 true WO2017087912A3 (fr) 2017-07-06

Family

ID=58719234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/062958 WO2017087912A2 (fr) 2015-11-20 2016-11-19 Biocapteurs ratiométriques et transfert d'énergie par résonance de förster non modulé géométriquement

Country Status (3)

Country Link
EP (1) EP3377610A4 (fr)
CA (1) CA3005883A1 (fr)
WO (1) WO2017087912A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
EP3377904B1 (fr) 2015-11-20 2024-05-01 Duke University Biocapteurs d'urée et leurs utilisations
US11099176B2 (en) 2015-11-20 2021-08-24 Duke University Lactate biosensors and uses thereof
WO2017087916A2 (fr) 2015-11-20 2017-05-26 Duke University Biocapteurs de glucose thermostables et leurs utilisations
JP2020510406A (ja) 2016-11-14 2020-04-09 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション プロテアーゼセンサー分子
WO2019014419A1 (fr) * 2017-07-14 2019-01-17 The Regents Of The University Of California Compositions et méthodes permettant d'améliorer l'éradication de cellules cancéreuses ou de tumeurs guidée par anticorps médiés par macrophages
KR102660777B1 (ko) 2017-08-08 2024-04-24 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 탄수화물 센서
CN110596072B (zh) * 2019-10-29 2022-05-13 陕西师范大学 基于聚酯纤维膜的比率型荧光纸芯片、制备方法和应用
EP4363826A1 (fr) 2021-07-01 2024-05-08 NanoTemper Technologies GmbH Procédés et dispositifs de caractérisation ratiométrique de particules fluorescentes
US20230174398A1 (en) * 2021-12-07 2023-06-08 Chemtreat, Inc. Fluorescence detection of sulfite in water treatment applications

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020004217A1 (en) * 1997-12-31 2002-01-10 Duke University Biosensor
US6432723B1 (en) * 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US20020142347A1 (en) * 2000-11-10 2002-10-03 Biosensor Aps Biosensor
US20030186229A1 (en) * 1996-01-31 2003-10-02 Tsien Roger Y. Emission ratiometric indicators of phosphorylation
US20060004271A1 (en) * 2004-07-01 2006-01-05 Peyser Thomas A Devices, methods, and kits for non-invasive glucose measurement
US20110117590A1 (en) * 2007-02-08 2011-05-19 Hillson Nathan J Heavy Metal Biosensor
US20120028265A1 (en) * 2007-08-10 2012-02-02 Thijs Kaper Methods of using ret nanosensors
US20140243223A1 (en) * 2008-09-23 2014-08-28 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186229A1 (en) * 1996-01-31 2003-10-02 Tsien Roger Y. Emission ratiometric indicators of phosphorylation
US20020004217A1 (en) * 1997-12-31 2002-01-10 Duke University Biosensor
US6432723B1 (en) * 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US20020142347A1 (en) * 2000-11-10 2002-10-03 Biosensor Aps Biosensor
US20060004271A1 (en) * 2004-07-01 2006-01-05 Peyser Thomas A Devices, methods, and kits for non-invasive glucose measurement
US20110117590A1 (en) * 2007-02-08 2011-05-19 Hillson Nathan J Heavy Metal Biosensor
US20120028265A1 (en) * 2007-08-10 2012-02-02 Thijs Kaper Methods of using ret nanosensors
US20140243223A1 (en) * 2008-09-23 2014-08-28 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HELM, P.: "Proposal of a New Method for Measuring Forster Resonance Energy Transfer (FRET) Rapidly, Quantitatively and Non-Destructively", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 13, 26 September 2012 (2012-09-26), pages 12367 - 12382, XP 055396116 *
RAIMONDO ET AL.: "A genetically-encoded chloride and pH sensor for dissociating ion dynamics in the nervous system", FRONTIERSINCELLULARNEUROSCIENCE, vol. 7, 13 November 2013 (2013-11-13), pages 1 - 10, XP055543195, DOI: 10.3389/fncel.2013.00202 *
See also references of EP3377610A4 *

Also Published As

Publication number Publication date
EP3377610A4 (fr) 2019-10-16
WO2017087912A2 (fr) 2017-05-26
CA3005883A1 (fr) 2017-05-26
EP3377610A2 (fr) 2018-09-26

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