WO2017080891A1 - Dispositif de soin capillaire, et procédé pour améliorer l'absorption d'un médicament topique dans les cheveux - Google Patents
Dispositif de soin capillaire, et procédé pour améliorer l'absorption d'un médicament topique dans les cheveux Download PDFInfo
- Publication number
- WO2017080891A1 WO2017080891A1 PCT/EP2016/076469 EP2016076469W WO2017080891A1 WO 2017080891 A1 WO2017080891 A1 WO 2017080891A1 EP 2016076469 W EP2016076469 W EP 2016076469W WO 2017080891 A1 WO2017080891 A1 WO 2017080891A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ultrasound
- hair
- topical
- care device
- hair care
- Prior art date
Links
- 210000004209 hair Anatomy 0.000 title claims abstract description 76
- 230000000699 topical effect Effects 0.000 title claims abstract description 51
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 11
- 238000000034 method Methods 0.000 title claims description 12
- 238000002604 ultrasonography Methods 0.000 claims abstract description 75
- 230000003699 hair surface Effects 0.000 claims abstract description 11
- 230000008859 change Effects 0.000 claims description 6
- 230000003287 optical effect Effects 0.000 claims description 4
- 238000011282 treatment Methods 0.000 description 17
- 230000003806 hair structure Effects 0.000 description 9
- 210000003491 skin Anatomy 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 5
- 238000009792 diffusion process Methods 0.000 description 4
- 238000007373 indentation Methods 0.000 description 4
- 239000013543 active substance Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 230000035699 permeability Effects 0.000 description 3
- 201000004384 Alopecia Diseases 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000003700 hair damage Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 description 1
- 206010068168 androgenetic alopecia Diseases 0.000 description 1
- 239000010478 argan oil Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 230000003646 hair health Effects 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229940107889 rogaine Drugs 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D24/00—Hair combs for care of the hair; Accessories therefor
- A45D24/22—Combs with dispensing devices for liquids, pastes or powders
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D2/00—Hair-curling or hair-waving appliances ; Appliances for hair dressing treatment not otherwise provided for
- A45D2/001—Hair straightening appliances
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D24/00—Hair combs for care of the hair; Accessories therefor
- A45D24/02—Single-piece combs
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D7/00—Processes of waving, straightening or curling hair
- A45D7/06—Processes of waving, straightening or curling hair combined chemical and thermal
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D19/00—Devices for washing the hair or the scalp; Similar devices for colouring the hair
- A45D19/16—Surface treatment of hair by steam, oil, or the like
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D2200/00—Details not otherwise provided for in A45D
- A45D2200/20—Additional enhancing means
- A45D2200/207—Vibration, e.g. ultrasound
Definitions
- the invention relates to a hair care device and method for enhancing uptake of a topical in hair.
- Topicals in hair include moisturization and protection. For example, excessive heat treatments of hair can cause a reduction in moisture content and potentially lead to hair damage or even breakage. Often it is advised to use a heat protection topical to safeguard the hair from excessive heat or to moisturize the hair when it is damaged. This resonates with consumers because they want to make their hair healthier and more resistant to damage from styling.
- the applied topicals can be in the form of oil (e.g. Argan oil), or watery solutions that contain a mixture of ingredients. These solutions are often applied by hand into the hair pre-styling but the downside is that the user has neither control over how well the topical is distributed on the hairs, nor how well the topical penetrates into the hair structure. Solutions can also be applied through appliances or onto appliances during styling to enhance protection to heat based styling or to moisturize the hair.
- US 5267985 provides a method and apparatus for enhancing the diffusion of a substance to a local area of material or tissue by providing ultrasonic energy to the substance and material in two or more distinct frequencies simultaneously.
- Each of the distinct frequencies of ultrasonic energy is chosen to enhance permeation of the substance through one or more diffusion rate-limiting sections of the material.
- the preferred frequency range for each signal is from 100 Hz to 100 MHz.
- Preferred combinations for two-frequency methods include 1 MHz & 3 MHz; 3 MHz & 9 MHz, and 5 MHz & 15 MHz.
- a first frequency may be selected to enhance diffusion of the substance through a first portion of the material.
- the material may be living tissue and the first portion of the material may be a stratum corneum layer of skin.
- the first frequency may lie in the range of 10 kHz to 100 MHz.
- This prior art document is primarily concerned with providing ultrasonic energy to living tissue in two or more distinct frequencies simultaneously in which a first portion of the material is a diffusion rate limiting membrane, so that a suitable first frequency is needed to enhance permeation of the substance through that first portion; hair (which is not a living tissue) is not discussed in this prior art document.
- US 20060272665 discloses an ultrasonic hair treatment device to apply ultrasonic vibrations to a user's hair for enhancing the penetration of a hair treatment composition into the hair.
- a piezoelectric transducer is supplied with an electric power and is controlled by a controller to produce vibrations of 500 kHz to 10 MHz frequency at a power of 0.1 to 5 W/cm 2 .
- WO 99/51295 discloses a system for enhancing and improving the transcutaneous or transdermal delivery of topical chemicals or drugs.
- a disposable container contains a substantially sterile unit dose of an active agent adapted for a single use in a medical treatment.
- the unit dose is formulated to enhance transport of the active agent through mammalian skin when the active agent is applied to the skin and the skin is exposed to light and/or ultrasound defined by at least one specific parameter.
- Preferred ultrasound parameters may be determined in accordance with both efficacy and safety requirements. For example, one preferred range for lower frequency ultrasound may be between about 25 kHz and about 3 MHz at about 0.5 - 2.0 W/cm 2 (either continuous or pulsed, using about a 20 - 25% duty cycle if pulsed).
- a preferred setting within this range may be at about 1.0 MHz at about 2.0 W/cm 2 , with a continuous wave beam and a treatment time of between about five and ten minutes.
- a preferred setting within this range for non-continuous beam i.e. pulsed delivery
- One preferred range for higher frequency ultrasound may be between about 3 MHz and about 16 MHz at about 0.2 - 1.0 W/cm 2 (either continuous or pulsed, using about a 20%> duty cycle if pulses), with a treatment time of between about one and twenty minutes.
- a preferred setting within this range may be at about 10 MHz at about 0.2 W/cm 2 , with a continuous treatment time of between about five and twenty minutes.
- a preferred embodiment may be useful to specifically stimulate (or inhibit) the growth of hair or other skin appendages (such as nails, etc.).
- a preferred embodiment may also be useful to stimulate the growth, or re-growth, of fine vellus or dormant or inactive hairs (e.g. to treat hair loss, for example).
- an object of the invention to provide an improved hair care device and method for enhancing uptake of a topical in hair.
- the invention is defined by the independent claims.
- Advantageous embodiments are defined in the dependent claims.
- Advantageous features of the hair care device are also advantageous features of the hair care method.
- Embodiments of the present invention feature ways to enhance the safe and effective uptake of topicals in the hair structure by using ultrasound (15 - 50 MHz) induced cavitation. This provides a simple and low-cost solution to enhance topical uptake by the hair structure before or during styling and thereby reducing the risk on hair damage.
- the lower frequency limit of 15 MHz has been chosen to trigger the largest inclusions to be activated on the hair surface.
- the upper frequency limit of 50 MHz has to do with the fact that, when frequency increases, the power needed to trigger smaller inclusions will increase as well. 50 MHz is preferred as the upper frequency limit since at this frequency we can still find a reasonable combination of duty cycle and treatment time to limit thermal issues.
- Embodiments of the present invention provide enhanced topical uptake for small and large tresses of hair. This is based on the insight that the indentation depth of cuticles is 0.3 - 2 ⁇ , resulting in poor hair permeability for frequencies in the kHz range up to 10 MHz. In phonophoresis, the increase in tissue permeability is mostly due to cavitating bubbles: therefore, low frequencies (20 - 100 kHz) are usually employed. In this context, acoustic cavitation refers broadly to violent oscillations of pre-existing gas inclusions.
- the typical size of the indentation depth between cuticle scales on a healthy and undamaged/untreated hair surface is about 0.3 - 0.5 ⁇ , i.e. approximately 1 cuticle cell.
- the indent can be much larger, in the order of 1 - 2 ⁇ .
- inertial cavitation increases significantly at higher frequencies (from about 2 W/cm 2 at 1 MHz to about 100 W/cm 2 at 50 MHz). Higher power usage leads to higher temperature increases per second.
- cavitation is used to increase the permeability of cuticle scales and to increase moisture uptake, cuticle scales should be closed after treatment (for instance using a conditioner or simply by surface moisturization) to avoid fast moisture loss after treatment.
- cavitation may be set at a very gentle reversible level, limiting the damage to cuticle: also to this purpose, the choice of higher frequencies (MHz range) will be beneficial.
- inertial cavitation will be induced in a range of bubbles with different radii.
- cavitation may occur in gas bubbles larger than the range of bubbles in hair cuticle. This should be avoided since this may cause violent cavitation, forming uncontrolled shock waves that may damage hair structures.
- the generated inertial cavitation is confined to the bubbles with radii within the range of the dimension of the hair cuticle indentation depth. The inventors have thus recognized that it is preferred to use ultrasound frequencies within the range of 20 MHz to 50 MHz to induce selective cavitation in hair cuticles for improved topical uptake.
- Embodiments of the present invention provide a safer treatment, as cavitation at low frequencies requires less energy than at higher frequencies and the range of bubbles excited tends to be larger.
- Ultrasound at megahertz frequencies will create less inertial cavitation (mechanical index cavitation). The higher the frequency the less violent cavitation is created, thereby reducing the likelihood of mechanically damaging the hair structure.
- Embodiments of the present invention provide ease of use, simple execution, low-power requirements, a small footprint, e.g. a small handheld device.
- Fig. 1 shows a first embodiment of the invention
- Fig. 2 shows a second embodiment of the invention
- Fig. 3 shows a third embodiment of the invention.
- Embodiments of the present invention provide a handheld, preferably cordless system which generates ultrasound to treat hairs coated by a topical for enhanced uptake of said topical.
- the ultrasound treatment is applied through direct contact with the topical covered hairs, preferably by clamping a tress of hair.
- Fig. 1 shows an ultrasound generator 103 which generates fixed or variable low- voltage ultrasound pulses, with frequency, voltage and pulse duration controlled by a controller 102 depending on treatment settings selected through a user interface 101.
- An acoustic amplifier 104 achieves the required output acoustic intensity.
- An ultrasound transducer 105 projects the ultrasound into the topical that is applied on to the hair surface 107.
- a practical embodiment will further feature a topical delivery unit for applying the topical to the hair.
- Piezoelectric crystals are used to produce ultrasound (> 20 kHz).
- Non- piezoelectric techniques like Capacitive Micro -machined Ultrasonic Transducers (CMUT) can be used for higher frequencies (typically up to -100 MHz) and can be used with this invention.
- the ultrasound transducer is embedded in the hair interface. It features a clamp to provide optimal contact with the hairs.
- the treatment clamps will be positioned close together in operating mode, where the distance between the clamps ideally should be smaller than one wavelength to promote uniformity, increasing the amplitude of the signal and time to result. Especially at higher frequencies this becomes an option since the energy is absorbed very quickly and might not even reach the opposed clamp. This will enable lower power usage and increase uniformity while enhancing cavitation to achieve better penetration into the hair structure.
- the ultrasound could be configured in pulsed mode with 1% duty cycle and a maximum treatment time of 4 s to stay below a maximum increased temperature threshold of 100 °C.
- Fig. 2 illustrates such a preferred embodiment, featuring a controller 202, an ultrasound generator and amplifier 203, a topical delivery unit 206, comb teeth 209 provided with ultrasound transducers 205, and a handle 211.
- the topical delivery unit 206 applies the topical to a surface of the hair structure.
- the controller 202 controls a level of ultrasound intensity and a predetermined duty cycle for applying the level of ultrasound intensity for improved topical uptake in a hair structure.
- the ultrasound transducers 205 have a topical contact surface for applying ultrasound energy to the topical.
- the ultrasound is applied to the topical close or on the hair surface. So the ultrasound applied to the topical will also interact with the hair.
- the controller may have a user interface.
- One alternative embodiment features two or multiple ultrasound transducers instead of one. Having two ultrasound sources or an array of ultrasound transducers opposed to each other in both clamps of the device will decrease the time to result and probably create constructive interference. If the distance between the clamps is not predetermined the chance of destructive interference is large. This will not happen if the distance between the closed clamps is exactly multiple times the wavelength of the frequency used or (2N+l)*lambda/4 for multiple ultrasound sources.
- Fig. 3 illustrates such an alternative embodiment, featuring ultrasound transducers 305 A and 305B on respective clamps 313 of a hair straightener, a controller 302, an ultrasound generator and amplifier 303, a topical delivery unit 306, and a swivel mechanism 315.
- the ultrasound intensity is in a range between 2 W/cm 2 and 100 W/cm 2 .
- the predetermined duty cycle is in a range between 1 % and 50 %.
- the inventors have found that at an ultrasound frequency of 20 MHz, a preferred upper limit of the duty cycle is 12.5 %, while at an ultrasound frequency of 50 MHz, the preferred upper limit of the duty cycle is 5 %.
- the hair care device comprises an array of ultrasound transducers.
- the controller comprises a look-up-table for determining the level of ultrasound intensity and the predetermined duty cycle for a specific hair type or topical.
- the hair care device comprises a sensor connected to the controller, the sensor being configured for sensing a parameter associated with the properties, e.g.
- the senor is selected from a list comprising a temperature sensor for sensing a temperature increase caused by the application of ultrasound, an optical sensor for sensing a change of the optical properties e.g. scattering, reflectance, caused by the application of ultrasound, an acoustical sensor for sensing a change of the acoustic properties, e.g. acoustic impedance, speed of sound, caused by the application of ultrasound, and an electrical sensor for sensing a change in electrical properties, e.g. radio frequency impedance, capacitance, caused by the application of ultrasound.
- a temperature sensor for sensing a temperature increase caused by the application of ultrasound
- an optical sensor for sensing a change of the optical properties e.g. scattering, reflectance, caused by the application of ultrasound
- an acoustical sensor for sensing a change of the acoustic properties, e.g. acoustic impedance, speed of sound, caused by the application of ultrasound
- an electrical sensor for sensing
- the controller is configured to stop the applying of ultrasound to the topical before a predetermined temperature limit is reached, the predetermined temperature limit being preferably 100 °C and more preferably 50 °C.
- the intensity and/or the duty cycle of the ultrasound could be adjusted so as to prevent the temperature from becoming too high.
- the transducer is in physical contact with the topical and/or the hair and positioned at a distance of preferably more than 0.3 cm, more preferably more than 1 cm, away from the skin surface.
- This distance ensures that the ultrasound application will have its intended positive effects without unintended negative effects to hair health.
- the hair care device preferably is provided with a suitable distance holder to ensure this minimum distance between the transducer and the skin surface.
- One alternative embodiment features systems and methods that initiate a feedback loop to measure attenuation of ultrasound in the hair structure to determine moisture content and adjust settings accordingly.
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2017015917A MX2017015917A (es) | 2015-11-13 | 2016-11-03 | Dispositivo para el cuidado del cabello y metodo para aumentar la absorcion de un producto topico en el cabello. |
EP16791375.5A EP3319472B1 (fr) | 2015-11-13 | 2016-11-03 | Dispositif et procédé de soin des cheveux |
JP2018521626A JP6480643B2 (ja) | 2015-11-13 | 2016-11-03 | 毛髪における外用剤の吸収を向上させるための毛髪ケア装置及び方法 |
US15/746,187 US20180235341A1 (en) | 2015-11-13 | 2016-11-03 | Hair care device and method for enhancing uptake of a topical in hair |
CN201680035385.2A CN107708473B (zh) | 2015-11-13 | 2016-11-03 | 用于增强毛发中外用物的吸收的毛发护理装置和方法 |
RU2018101233A RU2657167C1 (ru) | 2015-11-13 | 2016-11-03 | Устройство для ухода за волосами и способ увеличения усваивания волосами средства для местного применения |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15194604.3 | 2015-11-13 | ||
EP15194604 | 2015-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2017080891A1 true WO2017080891A1 (fr) | 2017-05-18 |
Family
ID=54544990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2016/076469 WO2017080891A1 (fr) | 2015-11-13 | 2016-11-03 | Dispositif de soin capillaire, et procédé pour améliorer l'absorption d'un médicament topique dans les cheveux |
Country Status (7)
Country | Link |
---|---|
US (1) | US20180235341A1 (fr) |
EP (1) | EP3319472B1 (fr) |
JP (1) | JP6480643B2 (fr) |
CN (1) | CN107708473B (fr) |
MX (1) | MX2017015917A (fr) |
RU (1) | RU2657167C1 (fr) |
WO (1) | WO2017080891A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020091464A1 (fr) * | 2018-10-31 | 2020-05-07 | (주)바이오인프라생명과학 | Procédé pour augmenter la viabilité d'une cellule par exposition de la cellule à un rayonnement d'ondes ultrasonores et appareil d'exposition à un rayonnement ultrasonore faisant appel à celui-ci |
KR20200049680A (ko) * | 2018-10-31 | 2020-05-08 | (주) 바이오인프라생명과학 | 초음파를 조사하여 세포의 생존율을 증가시키는 방법 및 이를 이용한 초음파 조사 장치 |
WO2023222781A1 (fr) * | 2022-05-18 | 2023-11-23 | L'oreal | Dispositif de traitement des cheveux et procédé |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3718431A1 (fr) * | 2019-04-03 | 2020-10-07 | Koninklijke Philips N.V. | Dispositif de soins capillaires doté d'un générateur d'ions |
RU2731906C1 (ru) * | 2019-12-08 | 2020-09-09 | Анастасия Валерьевна Рэм | Способ косметического воздействия на кератиновый материал лица, в частности, в области бровей и/или ресниц человека и устройство для его реализации |
RU2737021C1 (ru) * | 2020-04-28 | 2020-11-24 | Общество с ограниченной ответственностью "ХЭА ТЕХНОЛОДЖИ" | Устройство для стимуляции волосистой кожи головы и способ использования его |
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US5267985A (en) | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
WO1999051295A1 (fr) | 1998-04-03 | 1999-10-14 | Mcdaniel David H | Amelioration par ultrasons de l'absorption percutanee de medicaments |
EP1728450A2 (fr) * | 2005-06-01 | 2006-12-06 | Matsushita Electric Works, Ltd. | Dispositif de traitement de cheveux à ultrasons |
WO2008074005A1 (fr) * | 2006-12-13 | 2008-06-19 | Palomar Medical Technologies, Inc. | Applications cosmétiques et biomédicales d'énergie ultrasonore et procédés de génération de celles-ci |
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US6526988B2 (en) * | 1999-06-29 | 2003-03-04 | Kikuboshi Corporation | Method for treating hair shape and treating device thereof |
JP2001037526A (ja) * | 1999-08-03 | 2001-02-13 | Honda Electronic Co Ltd | 超音波パーマ装置 |
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JP4501828B2 (ja) * | 2005-09-27 | 2010-07-14 | パナソニック電工株式会社 | 超音波毛髪処理装置 |
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US20130125916A1 (en) * | 2011-11-23 | 2013-05-23 | Bacoustics, Llc | Ultrasound Hair Dyeing Method |
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US20150313993A1 (en) * | 2014-05-04 | 2015-11-05 | Robert T. Bock | Ultrasonic Method and Device for Cosmetic Applications |
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-
2016
- 2016-11-03 US US15/746,187 patent/US20180235341A1/en not_active Abandoned
- 2016-11-03 EP EP16791375.5A patent/EP3319472B1/fr active Active
- 2016-11-03 MX MX2017015917A patent/MX2017015917A/es unknown
- 2016-11-03 RU RU2018101233A patent/RU2657167C1/ru active
- 2016-11-03 JP JP2018521626A patent/JP6480643B2/ja active Active
- 2016-11-03 CN CN201680035385.2A patent/CN107708473B/zh active Active
- 2016-11-03 WO PCT/EP2016/076469 patent/WO2017080891A1/fr active Application Filing
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US5267985A (en) | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
WO1999051295A1 (fr) | 1998-04-03 | 1999-10-14 | Mcdaniel David H | Amelioration par ultrasons de l'absorption percutanee de medicaments |
EP1728450A2 (fr) * | 2005-06-01 | 2006-12-06 | Matsushita Electric Works, Ltd. | Dispositif de traitement de cheveux à ultrasons |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020091464A1 (fr) * | 2018-10-31 | 2020-05-07 | (주)바이오인프라생명과학 | Procédé pour augmenter la viabilité d'une cellule par exposition de la cellule à un rayonnement d'ondes ultrasonores et appareil d'exposition à un rayonnement ultrasonore faisant appel à celui-ci |
KR20200049680A (ko) * | 2018-10-31 | 2020-05-08 | (주) 바이오인프라생명과학 | 초음파를 조사하여 세포의 생존율을 증가시키는 방법 및 이를 이용한 초음파 조사 장치 |
KR102171510B1 (ko) | 2018-10-31 | 2020-10-29 | (주)바이오인프라생명과학 | 초음파를 조사하여 세포의 생존율을 증가시키는 방법 및 이를 이용한 초음파 조사 장치 |
WO2023222781A1 (fr) * | 2022-05-18 | 2023-11-23 | L'oreal | Dispositif de traitement des cheveux et procédé |
FR3135603A1 (fr) * | 2022-05-18 | 2023-11-24 | L'oreal | Dispositif de traitement des cheveux et procédé |
Also Published As
Publication number | Publication date |
---|---|
US20180235341A1 (en) | 2018-08-23 |
EP3319472B1 (fr) | 2019-01-09 |
EP3319472A1 (fr) | 2018-05-16 |
JP6480643B2 (ja) | 2019-03-13 |
JP2018533411A (ja) | 2018-11-15 |
MX2017015917A (es) | 2018-05-07 |
RU2657167C1 (ru) | 2018-06-08 |
CN107708473A (zh) | 2018-02-16 |
CN107708473B (zh) | 2020-07-07 |
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