WO2017067052A1

WO2017067052A1 - Pipette rack having magnetic base used for clean bench

Info

Publication number: WO2017067052A1
Application number: PCT/CN2015/098600
Authority: WO
Inventors: 邱一华; 彭聿平; 高江宁; 刘展; 曹蓓蓓
Original assignee: 南通大学
Priority date: 2015-10-19
Filing date: 2015-12-24
Publication date: 2017-04-27
Also published as: CN105149028A

Abstract

A pipette rack having a magnetic base used for a clean bench comprises a magnetic base (6) generating a magnetic attraction force, a side surface of the magnetic base (6) is a magnetic base attracting surface (4) for attracting the magnetic base onto an iron vertical side plate in a clean bench, a bottom surface (7) of the magnetic base contacts with a bottom surface in the clean bench, an upper surface of the magnetic base is fixedly installed with a standing rod base plate (3), and a standing rod (1) is disposed on the standing rod base plate (3); the standing rod (1) is installed with a horizontal member height positioning lock thereon, and a pipette rack horizontal member which is sleeved onto the standing rod (1) and can rotate horizontally on the standing rod (1) is disposed above the horizontal member height positioning lock; the pipette rack horizontal member comprises a connecting sleeve (18), the connecting sleeve (18) is connected to a pipette rack plate (16) through a horizontal arm (15), and the pipette rack plate (16) is provided with open-type pipette hanger slots (17) thereon through which pipettes can be vertically placed downwards.

Description

Ultra-clean platform with magnetic base pipette holder

Technical field

[0001] The present invention relates to a magnetic base pipette holder for a clean bench.

Background technique

[0002] In scientific research experiments, people often use the preset amount of liquid absorption in the aseptic environment provided by the clean bench (as long as the aspiration adjustment dial is rotated, the pipette can be preset) The pipette with the tip can realize the quantitative transfer of the test solution between the test tube, the reagent bottle, the culture flask, the beaker, the measuring cylinder, the measuring cup, the measuring flask and the conical flask. After sucking different volume of the experimental solution, just change the suction. Head, you can transfer experimental solutions of different functions. The experimental samples were processed by quantitative transfer of the above experimental solutions. This completes the dispensing, extraction, washing, incubation, etc. of the experimental samples under aseptic conditions.

[0003] Pipettes have become a tool for quantitative transfer solutions that are inseparable in scientific research experiments. They are used at a high frequency. Pipettes with a tip are used to absorb the same experimental solution. use. Since the pipette occupied by the horizontal position of the pipette is too large and the liquid pipette has been sucked, the liquid remaining in the pipette in the last pipetting may flow to the pipette and the tip connection portion. Causes contamination of the pipette. This requires people to prepare a vertically placed pipette holder for the pipette in the clean bench. To ensure the stability of the pipette holder after the pipette is placed, the pipette holder generally has a larger base area. However, a pipette rack with a large base area placed on the surface of the clean bench will occupy the bench space of the clean bench. This leads to the crowding of experimental samples, experimental reagents and laboratory equipment on the surface of super clean benches. This phenomenon hinders the rapid and efficient implementation of scientific research experiments and affects the accuracy and accuracy of scientific research experiments. Serious defects can lead to failure of scientific research experiments.

technical problem

[0004] The object of the present invention is to provide a magnetic force base pipette holder for a clean platform with reasonable structure, convenient use and adjustable space.

Problem solution

Technical solution

The technical solution of the present invention is: [0006] A magnetic base pipette holder for a clean bench, characterized in that: a magnetic seat for generating an adsorption magnetic force, and a side of the magnetic seat for adsorbing the magnetic base on a vertical side plate of the iron in the ultra-clean platform The magnetic seat adsorption surface, the bottom surface of the magnetic seat is in contact with the bottom surface of the ultra-clean table, the upper surface of the magnetic seat is fixed with the column bottom plate, and the column is provided on the column bottom plate; the horizontal member height positioning lock is mounted on the column, and the horizontal member height positioning lock is arranged above the set a pipette rack horizontal member that can be horizontally rotated on the column; the pipette frame horizontal member includes a connecting sleeve, and the connecting sleeve is used for fitting the pipette rack horizontal member on the column of the magnetic base, And help the horizontal part of the pipette holder to achieve large-angle movement in the horizontal direction, the connecting sleeve is connected with the pipette frame through the horizontal arm, and the mouthpiece of the mouthpiece is provided on the pipette holder plate, Place the pipette vertically downwards.

[0007] The horizontal member height positioning lock comprises a positioning lock body for forming a positioning cylindrical space of the positioning lock and the magnetic base column; the positioning lock body is composed of two left and right pieces, and the left and right two pieces are passed through the positioning lock hinge The connection enables the huddle cylindrical space of the positioning lock to be effectively spliced; the positioning lock fastening screw is arranged on the left and right side of the positioning lock body, and the positioning lock fastening screw is tightened to make the positioning lock tightly entangled in the magnetic On the column of the base, loosen the positioning lock fastening screw, remove the positioning lock to the magnetic base column, and move the position of the positioning lock up and down.

[0008] A positioning lock silicone pad is arranged in the positioning lock body, and the positioning lock silicone pad and the magnetic base column are engaged, so that the positioning lock is fixed at a height position required by the magnetic base column.

[0009] The magnetic seat includes a soft magnetic material, and a soft magnetic material is provided with a non-magnetic material that separates the soft magnetic material into uniform upper and lower halves, and a constant magnet is disposed in a cylindrical space surrounded by a soft magnetic material. The constant magnet and the constant magnet are connected to each other. When the constant magnet rotates to the off position, the N and S poles of the constant magnet are in a horizontal position, and the magnetic lines of force are separated by two soft magnetic materials separated by a non-magnetic material. In the closed circuit, the magnetic seat adsorption surface is not magnetic and can move freely; when the constant magnet rotates to the 幵 position, the N and S poles of the constant magnet are in the up and down position, and the N and S poles of the constant magnet are respectively aligned. The two soft magnetic materials of the magnetically permeable material are separated from the N pole to the soft magnetic material to the iron vertical side plate in the ultra clean table to another soft magnetic material to the S pole, forming a magnetic line close, and adsorbing the magnetic seat adsorption surface On the iron vertical side panel in the clean bench.

Advantageous effects of the invention

Beneficial effect

[0010] The present invention can occupy almost no clean bench space (especially a table space that does not occupy the center of the clean bench) Under the premise of the problem, the vertical placement of the pipette in the clean bench is solved. The position of the upper and lower spaces of the pipette holder can be changed by adjusting the position of the horizontal member height positioning lock on the column. The horizontal spatial position of the pipette holder can also be changed by adjusting the horizontal angle of the pipette holder horizontal member. It is conducive to the rapid, efficient and accurate operation of scientific research experiments in the ultra-clean platform. It can be seen that the magnetic base pipette holder for the ultra-clean platform of this application is a pipette holder with adjustable space, reasonable structure and convenient use which can be used in the ultra-clean platform.

Brief description of the drawing

DRAWINGS

[0011] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

1 is a front view of a magnetic base.

2 is a longitudinal cross-sectional view of a magnetic seat.

[0014] FIG. 3 is a top plan view of the horizontal member height positioning lock.

4 is a plan view of a pipette holder horizontal member.

[0016] In the figure:

[0017] 1. Column: vertically placed in the center of the upper surface of the magnetic seat, connected to the horizontal member of the pipette holder. The height of the column is 25-35cm (for example, 25cm, 30cm. 35cm), and the diameter of the column is 2-3cm (for example, 2cm, 2.5cm, 3cm).

[0018] 2. Chassis fixing screw: Fix the column chassis to the upper surface of the magnetic base.

[0019] 3. Column chassis: connected to the bottom end of the column, forming a fixed surface of the bottom end of the column and the upper surface of the magnetic seat.

[0020] 4. Magnetic seat adsorption surface: The magnetic base is adsorbed on the vertical side plate of the iron in the clean bench.

[0021] 5. Constant magnet rotation is turned off: The constant magnet is rotated to the off position, the magnetic force of the adsorption surface of the magnetic base disappears, and the magnetic base can be freely moved; the constant magnet is rotated to the position of the crucible, and the magnetic base adsorption surface generates a magnetic force. The magnetic base is firmly attached to the vertical side panel of the iron in the clean bench.

[0022] 6. Magnetic seat: The adsorption magnetic force is generated.

[0023] 7. The bottom of the magnetic base: contact with the bottom surface of the clean bench to increase the stability of the magnetic base.

8. Constant Magnet: A magnetic generating source.

[0025] 9. Non-magnetic material: The soft magnetic material of the magnetic seat is divided into uniform upper and lower halves.

[0026] 10. Soft magnetic material: According to the position of the constant magnet, the magnetic seat is separately magnetized, or demagnetized. [0027] 11. Positioning lock silicone pad: Cooperating with the magnetic base column to form a large static friction force, so that the positioning lock is well fixed at the height position required by the magnetic base column.

[0028] 12. Positioning lock fastening screw: Tightening the screw can make the positioning lock tightly fit on the column of the magnetic base; loose the screw, remove the positioning lock to the magnetic base column, and can move the positioning lock up and down s position.

[0029] 13. Positioning lock body: forming a positioning cylindrical lock and a magnetic base column.

[0030] 14. Positioning lock hinge: enables the cohesive cylindrical space of the positioning lock to be effectively engaged.

[0031] 15. Horizontal arm: connecting sleeve and pipette holder plate.

[0032] 16. Pipette holder plate: The formed portion of the pipette lower hanging groove is provided.

[0033] 17. Pipette under the hanging groove: The pipette can be placed vertically downward.

[0034] 18. Connecting sleeve: The pipette holder horizontal member is placed on the column of the magnetic base, and the horizontal movement of the pipette holder horizontal member is enabled (180 degree large angle movement).

BEST MODE FOR CARRYING OUT THE INVENTION

[0035] Example 1 :

[0036] A magnetic base pipette holder for a clean bench includes a magnetic seat for generating an adsorption magnetic force, and a side of the magnetic seat is a magnetic seat adsorption surface for adsorbing the magnetic base on a vertical side plate of the iron in the clean bench. The bottom surface of the magnetic base is in contact with the bottom surface of the ultra-clean platform, the upper surface of the magnetic base is fixed with the column bottom plate, and the column is provided on the column bottom plate; the horizontal member height positioning lock is mounted on the column, and the horizontal member height positioning lock is arranged above the column, a pipette holder horizontal member that rotates horizontally on the column; the pipette holder horizontal member includes a connecting sleeve for fitting the pipette holder horizontal member to the column of the magnetic base and assisting in pipetting The horizontal member of the frame realizes a large angle movement in the horizontal direction, the connecting sleeve is connected to the pipette frame through the horizontal arm, and the mouthpiece of the mouthpiece is provided on the pipette holder plate, which can be placed vertically downward Pipette.

[0037] The height of the column is 25 cm, and the diameter of the column is 2 cm.

[0038] The horizontal member height positioning lock comprises a positioning lock body for forming a positioning cylindrical space of the positioning lock and the magnetic base column; the positioning lock body is composed of two left and right pieces, and the left and right two pieces are passed through the positioning lock hinge The connection enables the huddle cylindrical space of the positioning lock to be effectively spliced; the positioning lock fastening screw is arranged on the left and right side of the positioning lock body, and the positioning lock fastening screw is tightened to make the positioning lock tightly entangled in the magnetic Base On the column, loosen the positioning lock fastening screw, remove the positioning lock to the magnetic base column, and move the positioning lock up and down.

[0039] A positioning lock silicone pad is arranged in the positioning lock body, and the positioning lock silicone pad and the magnetic base column are engaged, so that the positioning lock is fixed at a height position required by the magnetic base column.

[0040] The magnetic seat comprises a soft magnetic material, and a soft magnetic material is provided with a non-magnetic material that separates the soft magnetic material into uniform upper and lower halves, and a constant magnet is arranged in a cylindrical space surrounded by a soft magnetic material. The constant magnet and the constant magnet are connected to each other. When the constant magnet rotates to the off position, the N and S poles of the constant magnet are in a horizontal position, and the magnetic lines of force are separated by two soft magnetic materials separated by a non-magnetic material. In the closed circuit, the magnetic seat adsorption surface is not magnetic and can move freely; when the constant magnet rotates to the 幵 position, the N and S poles of the constant magnet are in the up and down position, and the N and S poles of the constant magnet are respectively aligned. The two soft magnetic materials of the magnetically permeable material are separated from the N pole to the soft magnetic material to the iron vertical side plate in the ultra clean table to another soft magnetic material to the S pole, forming a magnetic line close, and adsorbing the magnetic seat adsorption surface On the iron vertical side panel in the clean bench.

[0041] Method of use of the invention:

[0042] Pretreatment: Wiping the components of the magnetic base pipette holder with a disinfectant to ensure that the magnetic base pipette holder installed in the clean bench does not change the aseptic environment in the clean bench. (If it is used frequently, it can be placed in the clean bench for a long time, and it can be wiped and disinfected with disinfectant).

[0043] Installation of the magnetic base: Rotate the constant magnet 5 to the closed position. Thereafter, the N and S poles of the constant magnet 8 are in a horizontal position, and the magnetic lines of force form a closed circuit in the two soft magnetic materials 10 partitioned by the non-magnetic conductive material 9, and the magnetic seat adsorption surface 4 is free from magnetism and is free to move. Place the magnetic base (composed of 1-7) in the desired position. The specific operation is as follows: The magnetic seat adsorption surface 4 is in contact with the vertical side plate of the iron in the clean bench, and the bottom surface 7 of the magnetic seat is in contact with the bottom surface in the clean bench. . Rotating the constant magnet rotates to the position of the crucible. The N and S poles of the constant magnet are in the up and down position, and the N and S poles of the constant magnet are respectively aligned with the two soft magnetic materials separated by the non-magnetic material, from N From the soft magnetic material to the iron vertical side plate in the clean table to another soft magnetic material to the S pole, the magnetic field line is closed, and the magnetic seat adsorption surface can be firmly adsorbed on the iron vertical side in the ultra clean table. On the board.

[0044] Installation of the height positioning lock: Loosen the positioning lock fastening screw 12, put the cylindrical hole in the middle of the positioning lock (composed of 11-14) into the column 1, select the required height, and tighten the positioning lock fastening screw , the silicone pad 11 of the positioning lock is tightly engaged with the column.

[0045] Pipette horizontal member installation and pipette placement: Pipette holder horizontal member (15-18 common Constituting), the connecting sleeve 18 of the member is sleeved into the column, and the lower edge of the connecting sleeve is located at the upper edge of the height positioning lock to complete the height positioning. The inner diameter of the connecting sleeve is slightly larger than the outer diameter of the column, so that the connecting sleeve can be freely rotated on the column without causing significant oscillation on the column. At this point, the installation of the magnetic base pipette holder in the clean bench has been completed. For the sake of safety, the UV lamp can be sterilized twice. After the secondary sterilization is completed, the UV lamp is turned off. The position of the pipette holder 16 is rotated horizontally as needed for the experiment. Place the pipette vertically or remove the pipette from the pipette down slot (17). Since the root of the pipette extends to both sides, its width is greater than the diameter of the other parts of the pipette. Therefore, the pipette portion with a small width can be inserted into the lower slot of the pipette, and the root of the pipette with a large width is stuck above the pipe under the pipette, realizing the pipette on the pipette holder. Vertical placement.

[0046] Disassembly: The magnetic base pipette frame needs to be taken out from the clean bench. The horizontal member of the pipette holder can be moved vertically upwards to disengage the column, and the horizontal member of the pipette holder is removed. Tighten the screw, move it up vertically, take out the height positioning lock from the column, and finally rotate the constant magnet to the closed position and take out the magnetic base.

Example 2:

[0048] A magnetic base pipette holder for a clean bench includes a magnetic seat for generating an adsorption magnetic force, and a side of the magnetic seat is a magnetic seat adsorption surface for adsorbing the magnetic base on a vertical side plate of the iron in the clean bench. The bottom surface of the magnetic base is in contact with the bottom surface of the ultra-clean platform, the upper surface of the magnetic base is fixed with the column bottom plate, and the column is provided on the column bottom plate; the horizontal member height positioning lock is mounted on the column, and the horizontal member height positioning lock is arranged above the column, a pipette holder horizontal member that rotates horizontally on the column; the pipette holder horizontal member includes a connecting sleeve for fitting the pipette holder horizontal member to the column of the magnetic base and assisting in pipetting The horizontal member of the frame realizes a large angle movement in the horizontal direction, the connecting sleeve is connected to the pipette frame through the horizontal arm, and the mouthpiece of the mouthpiece is provided on the pipette holder plate, which can be placed vertically downward Pipette.

[0049] The height of the column is 30 cm, and the diameter of the column is 2.5 cm.

[0050] The horizontal member height positioning lock comprises a positioning lock body for forming a positioning cylindrical space of the positioning lock and the magnetic base column; the positioning lock body is composed of two left and right pieces, and the left and right two pieces are passed through the positioning lock hinge The connection enables the huddle cylindrical space of the positioning lock to be effectively spliced; the positioning lock fastening screw is arranged on the left and right side of the positioning lock body, and the positioning lock fastening screw is tightened to make the positioning lock tightly entangled in the magnetic On the column of the base, the loose positioning lock fastening screw removes the positioning lock to the magnetic base column, and can be used up and down. The position of the positioning lock is intended to be moved.

[0051] A positioning lock silicone pad is arranged in the positioning lock body, and the positioning lock silicone pad and the magnetic base column are engaged, so that the positioning lock is fixed at a height position required by the magnetic base column.

[0052] The magnetic seat includes a soft magnetic material, and a non-magnetic material that separates the soft magnetic material into uniform upper and lower halves is disposed in the soft magnetic material, and a constant magnet is disposed in the cylindrical space surrounded by the soft magnetic material The constant magnet and the constant magnet are connected to each other. When the constant magnet rotates to the off position, the N and S poles of the constant magnet are in a horizontal position, and the magnetic lines of force are separated by two soft magnetic materials separated by a non-magnetic material. In the closed circuit, the magnetic seat adsorption surface is not magnetic and can move freely; when the constant magnet rotates to the 幵 position, the N and S poles of the constant magnet are in the up and down position, and the N and S poles of the constant magnet are respectively aligned. The two soft magnetic materials of the magnetically permeable material are separated from the N pole to the soft magnetic material to the iron vertical side plate in the ultra clean table to another soft magnetic material to the S pole, forming a magnetic line close, and adsorbing the magnetic seat adsorption surface On the iron vertical side panel in the clean bench.

[0053] The method of use is the same as in the first embodiment.

Claims

Claim

A magnetic base pipette holder for a clean platform, comprising: a magnetic seat for generating an adsorption magnetic force, wherein a side of the magnetic seat is a magnetic seat for adsorbing the magnetic base on a vertical side plate of the iron in the clean bench The bottom surface of the magnetic base is in contact with the bottom surface of the clean bench, the upper surface of the magnetic base is fixed with the column bottom plate, and the column is provided with the column on the column bottom; the horizontal member height positioning lock is mounted on the column, and the horizontal member height positioning lock is arranged on the column, a pipette holder horizontal member rotatable horizontally on the column; the pipette holder horizontal member includes a connecting sleeve for fitting the pipette holder horizontal member to the column of the magnetic base and assisting in moving The horizontal member of the liquid container frame realizes a large angle movement in the horizontal direction, and the connecting sleeve is connected with the pipette frame plate through the horizontal arm, and the pipette holder plate is provided with a mouthpiece type pipette lower hanging groove, which can be vertically downward Place the pipette.

The magnetic base pipette holder for a clean bench according to claim 1 or 2, wherein: the horizontal member height positioning lock comprises a positioning lock body for forming a positioning cylinder of the positioning lock and the magnetic base column. The positioning lock body is composed of two left and right pieces, and the left and right two pieces are connected by a positioning lock hinge, so that the hug cylindrical space of the positioning lock can be effectively kneaded; the left and right two mouths of the positioning lock body are positioned and positioned. Lock the fastening screw, tighten the positioning lock fastening screw to make the positioning lock tightly fit on the column of the magnetic base, loosen the positioning lock fastening screw, remove the positioning lock to the magnetic base column, and move the positioning lock up and down s position. The magnetic base pipette holder for a clean bench according to claim 2, wherein: the positioning lock silicone pad is arranged in the positioning lock body, and the positioning lock silicone pad and the magnetic base column are engaged to fix the positioning lock to the magnetic body. The height position required for the base column.

The magnetic base pipette holder for a clean bench according to claim 1, 2 or 3, wherein: the magnetic seat comprises a soft magnetic material, and the soft magnetic material is disposed to separate the soft magnetic material into a uniform The non-magnetic material of the upper and lower halves is provided with a constant magnet in a cylindrical space surrounded by a soft magnetic material, and the constant magnet is connected to the constant magnet by a rotation, and when the constant magnet is rotated to a closed position, the constant magnet The N and S poles are in a horizontal position, and the magnetic lines of force form a closed circuit in the two soft magnetic materials separated by the non-magnetic material, and the magnetic seat adsorption surface is free from magnetism and can move freely; when the constant magnet rotates to the position of the crucible, The N and S poles of the constant magnet are in the up and down position. The N and S poles of the constant magnet are respectively aligned with two soft magnetic materials separated by a non-magnetic material, from the N pole to the soft magnetic material to the iron vertical side plate in the clean bench to another soft magnetic material to S The pole is formed to close the magnetic field line, and the magnetic seat adsorption surface is adsorbed on the iron vertical side plate in the clean bench.

[Claim 5] The magnetic base pipette holder for a clean bench according to claim 4, wherein:

Pretreatment: Wipe the components of the magnetic base pipette holder with disinfectant to ensure that the magnetic base pipette holder installed in the clean bench does not change the aseptic environment in the clean bench;

Installation of the magnetic base: Rotate the constant magnet to the closed position; here, the N and S poles of the constant magnet are in a horizontal position, and the magnetic lines of force form a closed circuit in the two soft magnetic materials separated by the non-magnetic material. The magnetic seat adsorption surface is not magnetic and can move freely; the magnetic base is placed at the desired position, and the specific operation is as follows: the magnetic seat adsorption surface is in contact with the iron vertical vertical plate in the ultra-clean platform, the magnetic base bottom surface and the ultra-clean platform The bottom surface contacts; the rotating constant magnet rotates to the position of the crucible, the N and S poles of the constant magnet are in the upper and lower positions, and the N and S poles of the constant magnet are respectively aligned with the two soft magnetic materials separated by the non-magnetic material. From the N pole to the soft magnetic material to the iron vertical side plate in the ultra clean table to another soft magnetic material to the S pole, forming a magnetic line close, and the magnetic seat adsorption surface firmly adheres to the iron in the ultra clean table Vertical side panel;

Installation of the height positioning lock: Loosen the positioning lock fastening screw, put the cylindrical hole in the middle of the positioning lock into the column, select the required height, tighten the positioning lock fastening screw, and make the silicone pad of the positioning lock tightly fit the column. ;

Pipette horizontal member installation and pipette placement: Take the pipette holder horizontal member, put the connecting sleeve of the member into the column, the lower edge of the connecting sleeve is located at the upper edge of the height positioning lock, complete the height Positioning; the diameter of the inner ring of the connecting sleeve is slightly larger than the outer diameter of the column, so that the connecting sleeve can be freely rotated on the column without causing a significant swing on the column; thus, the magnetic base has been moved Installation of the liquid holder in the clean bench; according to the experimental requirements, horizontally rotate the position of the pipette holder; place the pipette vertically or remove the pipette from the lower channel of the pipette; as the root of the pipette extends to the sides , so its width is larger than the diameter of the other parts of the pipette; so the pipette part with a small width can be inserted into the lower groove of the pipette, and The root of the wide pipette is stuck above the pipette under the pipette, realizing the vertical placement of the pipette on the pipette holder;

Disassembly: The magnetic base pipette frame needs to be removed from the clean bench. Move the horizontal part of the pipette holder vertically upwards to disengage it from the column, remove the horizontal part of the pipette holder, and loosen the positioning lock fastening screw. Move vertically upwards, remove the height positioning lock from the column, and finally rotate the constant magnet to the closed position, and take out the magnetic base.