WO2017043693A1

WO2017043693A1 - Artificial blood vessel

Info

Publication number: WO2017043693A1
Application number: PCT/KR2015/011509
Authority: WO
Inventors: 문병주
Original assignee: 문병주
Priority date: 2015-09-11
Filing date: 2015-10-29
Publication date: 2017-03-16
Also published as: KR20170031371A; KR101779460B1

Abstract

The present invention relates to an artificial blood vessel comprising: a cylindrical inner tube having a cavity formed therein; an outer tube provided at an outer circumferential surface of the inner tube, and encompassing the inner tube so as to form a dual tube structure with the inner tube; and connection lines formed along the circumferential direction of the inner tube and the outer tube, so as to connect the inner tube with the outer tube.

Description

Artificial blood vessel

The present invention relates to artificial blood vessels.

Vascular obstruction caused by narrowing or almost clogging of blood vessels due to lack of exercise and westernization are increasing year by year.

In particular, most of the heart diseases are coronary artery disease and peripheral vascular disease caused by ischemia, which is clogging the blood vessels that supply nutrition and oxygen to the heart.

Surgical methods are often adopted as a method for treating such closed vessels or substantially closed vessels. Commonly used as a surgical method is to cut out the blood vessels in question and then try to solve the stenosis problem by inserting artificial blood vessels.

A representative example thereof is the artificial blood vessel 10 shown in FIG. 1, and the artificial blood vessel 10 may guide blood flow when a patient's own blood vessel is narrowed due to a certain factor or its function is significantly degraded. Has been developed as an alternative.

The conventional artificial blood vessel 10 is made of a hollow tube 11 is formed through which blood flows, the tube 11 is made of a single tube in which wrinkles 12 are formed.

However, anastomosis of the artificial blood vessel 10 and the artificial blood vessel 10 of the blood vessel and the blood vessel in the region where the periodic pulsation is continuously progressing is very difficult. In particular, the longer the operation time, the more difficult the operation, and if the operation time is too long, there is a problem that increases the risk of complications. In particular, if applied to the aortic part, suture surgery must be completed in a short time to prevent the outflow of a lot of blood.

Therefore, there is a need for artificial blood vessels that can be applied quickly and safely to the surgical site when artificial blood vessels are inserted.

The present invention is to provide an artificial blood vessel that can be applied quickly and safely during vascular replacement surgery.

The present invention is a cylindrical inner tube hollow is formed therein; An outer circumference of the inner tube, the outer tube surrounding the inner tube to have a double tube structure; And it is formed along the circumferential direction of the inner tube and the outer, connecting lines for connecting the inner tube and the exterior; to provide an artificial blood vessel comprising a.

Artificial blood vessels according to the present invention is formed in a double tube structure, it can be performed quickly and safely vascular replacement surgery.

In particular, the present invention enables a quick and safe reinforcement anastomosis of the complex process of reinforcing the aortic dissection and anastomosis in acute aortic dissection or chest and abdominal aortic aneurysm surgery.

1 is a view showing a conventional artificial blood vessels.

2 is a schematic diagram of artificial blood vessels according to an embodiment of the present invention.

3 is a cross-sectional view of an artificial blood vessel according to an embodiment of the present invention.

4 is a view showing a process of anastomosis with artificial blood vessels according to an embodiment of the present invention.

5 is a view showing a portion of artificial blood vessels according to an embodiment of the present invention.

6 is a schematic diagram of artificial blood vessels according to another embodiment of the present invention.

7 is a cross-sectional view illustrating a process of anastomosis with artificial blood vessels according to an embodiment of the present invention.

The present invention relates to artificial blood vessels that can be applied quickly and safely during vascular replacement surgery.

Here, artificial blood vessels refer to artificial organs used to remove damaged blood vessels and connect blood flow in vivo, and mean artificially made arteries or veins.

Artificial blood vessel of the present invention is a cylindrical inner tube is hollow formed therein; An outer circumference of the inner tube, the outer tube surrounding the inner tube to have a double tube structure; And a connection line formed along the circumferential direction of the inner tube and the outer tube to connect the inner tube and the outer tube.

Here, the connection means to join the inner tube and the exterior.

In this case, the connection line may include a plurality, and may be formed to be spaced apart at predetermined intervals along the axial direction of the inner tube and the outer surface.

In addition, the inner tube may include at least one first guide line along the axial direction, and the appearance may include at least one second guide line along the axial direction. In particular, it is characterized in that it is formed to match the position of the first guide line.

The first guide line and the second guide line are for preventing the artificial blood vessel of the present invention from twisting, and may be a marking means for indicating a position for closing the blood vessel.

In addition, the inner tube and the outer tube of the artificial blood vessel of the present invention may be made of a corrugated tube, and may include at least one branch tube to branch.

Artificial blood vessels are made of biocompatible materials and include nylon, silk, polytetrafluoroethylene (PTFE), polypropylene (PP), polyurethane (PU), polyethylene terephthalate (PET), polyamide (PA), Polyacrylonitrile (PAN), Polyethylene (PE), Polyester (PES), Polyvinylchloride (PVC), Polyvinylidene fluoride (PVDF), Polysiloxane (Silicone Rubber), Polyvinyl alcohol (PVA), Polyglycol (PGA) and polylactic acid (PLA).

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings. Prior to this, terms or words used in the present specification and claims should not be construed as being limited to the common or dictionary meanings, and the inventors should properly explain the concept of terms in order to best explain their own invention. Based on the principle that can be defined, it should be interpreted as meaning and concept corresponding to the technical idea of the present invention.

Therefore, the embodiments described in the specification and the drawings shown in the drawings are only the most preferred embodiment of the present invention and do not represent all of the technical idea of the present invention, various modifications that can be replaced at the time of the present application It should be understood that there may be equivalents and variations.

2 is a schematic diagram of artificial blood vessels according to an embodiment of the present invention, Figure 3 is a cross-sectional view of artificial blood vessels according to an embodiment of the present invention, Figure 4 is a process of anastomosis artificial blood vessels according to an embodiment of the present invention with blood vessels 5 is a view showing a portion of artificial blood vessels according to an embodiment of the present invention, Figure 6 is a schematic diagram of artificial blood vessels according to another embodiment of the present invention, Figure 7 according to an embodiment of the present invention Figure is a cross-sectional view showing the process of anastomosis artificial blood vessels with blood vessels.

Hereinafter, the artificial blood vessel of the present invention will be described in detail with reference to FIGS. 2 to 7.

The present invention relates to an artificial blood vessel 10 that can be applied quickly and safely during vascular replacement surgery.

Here, artificial blood vessel (10) refers to an artificial organ used to remove blood vessels damaged in the living body and connect blood flow, and means an artificial artery or venous blood vessel.

The artificial blood vessel 10 of the present invention can be applied to all damaged blood vessels such as arteries, veins, capillaries, etc. In particular, the present invention is used to reinforce the aortic dissection site during acute aortic dissection or chest and abdominal aortic aneurysm surgery. The artificial blood vessel 10 may be.

As shown in Figures 2 and 3, the artificial blood vessel 10 of the present invention is characterized in that it is formed in a double tube structure consisting of a cylindrical inner tube 100 and the exterior 200.

More specifically, the inner tube 100 and the inner tube 100 is formed on the outer circumferential surface of the inner tube 100, the inner tube 100 includes an outer tube 200 configured to surround the inner tube 100, and the inner tube 100 and It characterized in that it comprises a connecting line 210 along the circumferential direction of the artificial blood vessel 10 to connect the appearance (200).

As a specific embodiment, the artificial blood vessel 10 is formed so that the cross-sectional structure has a circular structure, and as used, may be composed of blood vessels of large diameter, such as veins and arteries of the human body, or blood vessels of small diameter, such as capillaries. Can be. In addition, the artificial blood vessel 10 may be formed in a structure having an outer skin layer formed in the order of the inner hollow (tunica interna), the middle film (tunica media), the outer film (tunica externa), such as a natural blood vessel, but artificial Considering that it is the blood vessel 10, the function and appearance 200 need not be limited to the shape if the shape is similar to natural blood vessels.

At this time, the connection line 210 of the present invention is for bonding the inner tube 100 and the outer shell 200 of the present invention, the inner tube 100 and the outer shell 200 may be made to be sealed, as a specific aspect, adhesive The inner tube 100 and the exterior 200 may be bonded by a material.

For reference, the inner tube 100 and the outer tube 200 are not joined to the entire area, but only a predetermined portion is bonded to each other. The inner tube 100 and the outer tube 200, which are portions where the connecting line 210 is not formed, are connected to each other. An empty space may be formed.

More specifically, the connecting line 210 may include a plurality of rings in the circumferential direction of the artificial blood vessel 10, and may be formed to be spaced apart at predetermined intervals along the axial direction of the inner tube 100 and the exterior 200. Can be.

Here, the axial direction means a direction extending in the longitudinal direction of the artificial blood vessel 10, in particular, may mean a direction parallel to the main axis of the inner tube 100 and the outer tube 200.

In a particular embodiment, the connection line 210 of the present invention may function to minimize blood leakage during the artificial vessel 10 and vascular anastomosis surgery.

As shown in Figure 4, during the vascular anastomosis surgery vessel 1 is coupled to be located between the inner tube 100 and the exterior 200 of the present invention. More specifically, the inner diameter of the blood vessel 1 may be located on the outer circumferential surface of the inner tube 100 in the present invention, and the outer diameter of the blood vessel 1 may be located on the inner circumferential surface of the exterior 200 in the present invention. That is, the cut surface of the blood vessel 1 is located in the empty space between the inner tube 100 and the surgical 200 of the present invention, wherein the cut surface of the blood vessel 1 has a sealing effect by the connecting line 210 Can occur, thereby minimizing blood leakage.

In this case, the plurality of connecting lines 210 may be formed at intervals of 2 to 6 cm along the axial direction of the artificial blood vessel 10, and more specifically, the interval of the connecting lines 210 at the artificial blood vessel 10 is 4 to 6 cm. It may be formed, for example, may be formed at 5cm intervals. In addition, in the case of the branch pipe 500 having a small diameter may be formed at intervals of 2 to 3cm.

In addition, when the plurality of connecting lines 210 are formed at a spacing of 5 cm, the user may cut and use the connecting line 210 and the connecting line 210, and at this time, cut a point 2.5 cm from the connecting line 210. Can be used.

In particular, the artificial blood vessel 10 of the present invention is partitioned by the connecting line 210, it can be used to cut the length to be used.

In addition, the artificial blood vessel 10 of the present invention is characterized in that it comprises a guide line (400). More specifically, the inner tube 100 and the outer tube 200 may include at least one guide line 400 along an axial direction, and the guide line 400 formed on the inner tube 100 may be a first guide line. The guide line 400 formed on the exterior 200 may be a second guide line 420.

In this case, as shown in FIG. 5, the first guide line 410 of the inner tube 100 and the second guide line 420 of the exterior 200 may be formed at positions corresponding to each other.

The guide line 400 is to prevent the inner tube 100 and the exterior 200 of the artificial blood vessel 10 from twisting, and may be a marking means for indicating a position for suturing the blood vessel 1.

For example, three first guide lines 410 may be formed along the axial direction of the inner tube 100, and second guide lines 420 may be formed at three locations along the axial direction of the exterior 200.

At this time, in order to anastomize the blood vessel 1 and the artificial blood vessel 10, the first guide line 410 and the second guide line 420 are formed at a corresponding position, and only a portion where the guide line 400 is formed. You can anastomulate first.

That is, after the first guide line 410 and the second guide line 420 are positioned to correspond to the suture 300 in the portion where the guide line 400 is formed so that the blood vessel 1 and the artificial blood vessel 10 are not twisted. The anastomosis of blood vessels 1 may be performed, and then the suture 300 anastomated to the guide line 400 may be extended to anastomulate the remaining portion.

On the other hand, as shown in Figure 6, the inner tube 100 and the outer tube 200 of the artificial blood vessel 10 of the present invention may be made of a corrugated tube, at least one branch pipe 500 to branch from the artificial blood vessel 10 ) May be included.

At this time, it is not limited to this, for example, it may be a branched vessel of a cylindrical shape having a predetermined diameter, or may be a flare branched vessel that increases in diameter as the portion connected to the artificial blood vessel 10. . For reference, in order to facilitate blood flow in the artificial blood vessel 10, a flare branched blood vessel member may be used.

Meanwhile, the artificial blood vessel 10 is made of a biocompatible material and includes nylon, silk, polytetrafluoroethylene (PTFE), polypropylene (PP), polyurethane (PU), polyethylene terephthalate (PET), and polyamide ( PA), polyacrylonitrile (PAN), polyethylene (PE), polyester (PES), polyvinyl chloride (PVC), polyvinylidene fluoride (PVDF), polysiloxane (Silicone Rubber), polyvinyl alcohol (PVA) , Polyglycol (PGA) and polylactic acid (PLA) may be at least one selected from the group consisting of.

The artificial blood vessel 10 of the present invention is not limited thereto, but may be an artificial blood vessel 10 for a carotid artery, an iliac bone, or a femoral artery, which is a medium artery, and an artificial blood vessel for replacement of a wide artery, such as an aorta, 10 May be). In this case, the diameter of the artificial blood vessel 10 may be 10 to 45mm, the branch pipe 500 may be 3 to 12mm.

In addition, the artificial blood vessel 10 of the present invention may have a length of 10 to 50cm. Although not limited thereto, the artificial blood vessel 10 may be cut by a length necessary for surgery.

An example of treating an aneurysm using the artificial blood vessel 10 according to the present invention is as follows. For easy description of the present invention, the process of anastomizing the blood vessel 1 and the artificial blood vessel 10 of the present invention will be described as an example with reference to FIG. 7.

First, the surgeon cuts the artificial blood vessel 10 of the present invention by the length required for surgery. At this time, the center portion between the connection line 210 and the connection line 210 formed in the artificial blood vessel 10 can be cut.

Thereafter, the blood vessel 1 of the patient and the cut artificial blood vessel 10 are superimposed. In this case, the blood vessel 1 of the patient is located between the inner tube 100 and the exterior 200 of the artificial blood vessel 10, and more specifically, the length of the blood vessel 1 and the artificial blood vessel 10 of the patient is 1. To 2 cm overlap.

Meanwhile, the first guide line 410 and the second guide line 420 formed on the inner tube 100 and the outer tube 200 of the artificial blood vessel 10 are formed at the same position, and the guide line 400 is formed. The portion is anastomated with the suture 300.

Only the portion where the guide line 400 is formed may be anastomated with the suture 300, and then anastomulated as a whole to anastomulate the blood vessel 1 and the artificial blood vessel 10 of the present invention.

Therefore, the artificial blood vessel 10 according to the present invention is formed in a double tube structure, and can perform vascular replacement surgery quickly and safely.

In particular, the present invention can quickly and safely augment the complex process of augmenting the aortic dissection site and anastomosis of the artificial vessel 10 during acute aortic dissection or chest and abdominal aortic aneurysm surgery.

In the present invention as described above has been described by the specific embodiments, such as specific components and limited embodiments and drawings, but this is provided to help a more general understanding of the present invention, the present invention is not limited to the above embodiments. For those skilled in the art, various modifications and variations are possible from these descriptions.

Therefore, the spirit of the present invention should not be limited to the described embodiments, and all of the equivalents and equivalents of the claims, as well as the following claims, will fall within the scope of the present invention. .

1: blood vessel

10: artificial blood vessel

11: tube 12: pleat

100: inner tube 200: appearance

210: connecting line 300: suture

400: guide line 410: first guide line

420: second guide line 500: branch pipe

Claims

A cylindrical inner tube having a hollow formed therein;

An outer circumference of the inner tube, the outer tube surrounding the inner tube to have a double tube structure; And

Artificial blood vessels including a connecting line formed along the circumferential direction of the inner tube and the exterior, connecting the inner tube and the exterior.
The method of claim 1,

The connecting line includes a plurality,

Artificial blood vessels, characterized in that formed in the axial direction of the inner tube and spaced apart at a predetermined interval.
The method of claim 1,

The inner tube is

Artificial blood vessels, characterized in that it comprises at least one first guide line along the axial direction.
The method of claim 3,

The appearance is

And at least one second guide line along the axial direction, wherein the artificial blood vessel is formed to coincide with the position of the first guide line.
The method of claim 1,

The inner tube and exterior

Artificial blood vessels, characterized in that consisting of a corrugated tube.
The method of claim 1,

The artificial blood vessel is

Artificial blood vessels, characterized in that it comprises at least one branch to branch.
The method of claim 1,

The inner tube and exterior

Nylon, silk, polytetrafluoroethylene (PTFE), polypropylene (PP), polyurethane (PU), polyethylene terephthalate (PET), polyamide (PA), polyacrylonitrile (PAN), polyethylene (PE) , Polyester (PES), polyvinyl chloride (PVC), polyvinylidene fluoride (PVDF), polysiloxane (Silicone Rubber), polyvinyl alcohol (PVA), polyglycol (PGA) and polylactic acid (PLA) Artificial blood vessels, characterized in that at least one selected from.