WO2017036893A1 - Dispositif de prise de vue, appareil d'observation optique et procédé d'acquisition d'images - Google Patents
Dispositif de prise de vue, appareil d'observation optique et procédé d'acquisition d'images Download PDFInfo
- Publication number
- WO2017036893A1 WO2017036893A1 PCT/EP2016/070023 EP2016070023W WO2017036893A1 WO 2017036893 A1 WO2017036893 A1 WO 2017036893A1 EP 2016070023 W EP2016070023 W EP 2016070023W WO 2017036893 A1 WO2017036893 A1 WO 2017036893A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- light
- observation object
- filter
- light source
- image
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title claims description 18
- 238000000034 method Methods 0.000 title claims description 15
- 230000005284 excitation Effects 0.000 claims abstract description 55
- 230000005540 biological transmission Effects 0.000 claims abstract description 28
- 230000003595 spectral effect Effects 0.000 claims description 50
- 238000003384 imaging method Methods 0.000 claims description 7
- 238000001228 spectrum Methods 0.000 claims description 4
- 238000005286 illumination Methods 0.000 description 32
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 24
- 229960004657 indocyanine green Drugs 0.000 description 24
- 229910052724 xenon Inorganic materials 0.000 description 6
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 6
- 238000011156 evaluation Methods 0.000 description 5
- 238000002189 fluorescence spectrum Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000000862 absorption spectrum Methods 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000007850 fluorescent dye Substances 0.000 description 3
- 229910052736 halogen Inorganic materials 0.000 description 3
- 150000002367 halogens Chemical class 0.000 description 3
- 229910001507 metal halide Inorganic materials 0.000 description 3
- 150000005309 metal halides Chemical class 0.000 description 3
- 238000001454 recorded image Methods 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 239000002872 contrast media Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000002073 fluorescence micrograph Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/0012—Surgical microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/20—Filters
- G02B5/208—Filters for use with infrared or ultraviolet radiation, e.g. for separating visible light from infrared and/or ultraviolet radiation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
L'invention concerne un dispositif de prise de vue (1). Ce dispositif de prise de vue comprend un ensemble source lumineuse (13) conçu pour émettre de la lumière comprenant de la lumière visible (11) et de la lumière d'excitation (10) destinée à exciter une émission infrarouge dans un objet à observer (4), un dispositif d'acquisition (3) comportant un capteur d'image pour acquérir une image d'un objet à observer (4) exposé à la lumière de l'ensemble source lumineuse (13) et, un filtre d'acquisition (9) qui est disposé entre l'objet à observer (4) et le capteur d'image du dispositif d'acquisition (3) et dont la caractéristique de transmission est configurée de manière à laisser passer la lumière visible (16) réfléchie par l'objet à observer (4) et la lumière infrarouge (12) émise par l'objet à observer (4), mais à bloquer la lumière d'excitation (10) réfléchie par l'objet à observer (4). L'ensemble source lumineuse (13) peut être réglé de manière à émettre soit uniquement la lumière visible (11), soit uniquement la lumière d'excitation (10) en direction de l'objet à observer (4).
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102015114485 | 2015-08-31 | ||
| DE102015114485.9 | 2015-08-31 | ||
| DE102016104439.3 | 2016-03-10 | ||
| DE102016104439.3A DE102016104439A1 (de) | 2015-08-31 | 2016-03-10 | Bildaufnahmeanordnung, optisches Beobachtungsgerät und Verfahren zum Aufnehmen von Bildern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2017036893A1 true WO2017036893A1 (fr) | 2017-03-09 |
Family
ID=58011512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2016/070023 WO2017036893A1 (fr) | 2015-08-31 | 2016-08-24 | Dispositif de prise de vue, appareil d'observation optique et procédé d'acquisition d'images |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE102016104439A1 (fr) |
| WO (1) | WO2017036893A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018187442A1 (fr) * | 2017-04-07 | 2018-10-11 | Verily Life Sciences Llc | Optique à motifs pour collecte d'épi-fluorescence |
| WO2023109850A1 (fr) * | 2021-12-14 | 2023-06-22 | 微创优通医疗科技（上海）有限公司 | Module d'éclairage, système d'imagerie endoscopique, endoscope et procédé d'imagerie associé |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017124787A1 (de) * | 2017-10-24 | 2019-04-25 | Asphericon Gmbh | Beleuchtungsvorrichtung für eine transkutane Fluoreszenzbiopsie |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006025802A (ja) * | 2003-06-17 | 2006-02-02 | Olympus Corp | 内視鏡装置 |
| US20080251694A1 (en) | 2007-02-05 | 2008-10-16 | Sanyo Electric Co., Ltd. | Image pickup apparatus |
| EP2199842A1 (fr) * | 2008-12-17 | 2010-06-23 | Carl Zeiss Surgical GmbH | Microscope chirurgical pour observer une fluorescence à infrarouge et procédé correspondant |
-
2016
- 2016-03-10 DE DE102016104439.3A patent/DE102016104439A1/de not_active Withdrawn
- 2016-08-24 WO PCT/EP2016/070023 patent/WO2017036893A1/fr active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006025802A (ja) * | 2003-06-17 | 2006-02-02 | Olympus Corp | 内視鏡装置 |
| US20080251694A1 (en) | 2007-02-05 | 2008-10-16 | Sanyo Electric Co., Ltd. | Image pickup apparatus |
| EP2199842A1 (fr) * | 2008-12-17 | 2010-06-23 | Carl Zeiss Surgical GmbH | Microscope chirurgical pour observer une fluorescence à infrarouge et procédé correspondant |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018187442A1 (fr) * | 2017-04-07 | 2018-10-11 | Verily Life Sciences Llc | Optique à motifs pour collecte d'épi-fluorescence |
| CN110494738A (zh) * | 2017-04-07 | 2019-11-22 | 威里利生命科学有限责任公司 | 用于落射荧光收集的图案化的光学器件 |
| US10908404B2 (en) | 2017-04-07 | 2021-02-02 | Verily Life Sciences Llc | Patterned optic for epi-fluorescence collection |
| WO2023109850A1 (fr) * | 2021-12-14 | 2023-06-22 | 微创优通医疗科技（上海）有限公司 | Module d'éclairage, système d'imagerie endoscopique, endoscope et procédé d'imagerie associé |
Also Published As
| Publication number | Publication date |
|---|---|
| DE102016104439A1 (de) | 2017-03-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE102006004232B4 (de) | Mikroskopiesystem | |
| DE10141559B4 (de) | Videoendoskopsystem und Beleuchtungsoptik | |
| DE102008018636B4 (de) | Vorrichtung und Verfahren zur endoskopischen 3D-Datenerfassung | |
| EP2108943B1 (fr) | Dispositif et procédé d'imagerie à fluorescence | |
| DE10053447B4 (de) | Endoskopsystem | |
| DE102010044502A1 (de) | Sonderbeleuchtungs-Video-Operations-Stereomikroskop | |
| DE102014016850B4 (de) | Optisches System zur Fluoreszenzbeobachtung | |
| DE102020105458A1 (de) | Medizinische Bildgebungsvorrichtung | |
| DE102013009817B4 (de) | Mikroskopiesystem zur Beobachtung von Fluoreszenz in der Ophthalmologie | |
| EP1389943B1 (fr) | Ophtalmoscope | |
| DE102009025127A1 (de) | Beleuchtungseinrichtung für ein optisches Beobachtungsgerät | |
| DE10242983B4 (de) | Ophthalmo-Operationsmikroskop mit Objektbeleuchtung | |
| DE102014103044A1 (de) | Chirurgisches Assistenzsystem | |
| DE102014008243A1 (de) | Fluoreszenbeobachtungssystem und optisches Filtersystem hierfür | |
| DE102007023270A1 (de) | Funduskamera | |
| DE102010039950A1 (de) | Mikroskop mit Mikro- und Makro-Objektiven | |
| DE102015103426A1 (de) | Mikroskopsystem und Verfahren zum automatisierten Ausrichten eines Mikroskops | |
| DE102009017710B4 (de) | Optisches Beobachtungsgerät und Verfahren zum Gewährleisten einer gleich bleibenden Beleuchtungsintensität bei einem Wechsel der Farbtemperatur der Beleuchtung | |
| EP2950130A1 (fr) | Système de microscope avec profondeur de champ | |
| WO2017036893A1 (fr) | Dispositif de prise de vue, appareil d'observation optique et procédé d'acquisition d'images | |
| DE102018110806A1 (de) | Operationsmikroskop mit einer Beleuchtungsvorrichtung | |
| DE10156434A1 (de) | Videoendoskop und Videoendoskopsystem | |
| DE4323129A1 (de) | Lasermikroskop | |
| DE102017210274A1 (de) | Mikroskopiesystem und Mikroskopieverfahren zur Aufnahme von Fluoreszenzlichtbildern und Weißlichtbildern | |
| DE102009010446B4 (de) | Verfahren und Vorrichtung zur Quantifizierung des Blutflusses in einem Gewebebereich |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 16763217 Country of ref document: EP Kind code of ref document: A1 |
|
| NENP | Non-entry into the national phase |
Ref country code: DE |
|
| 122 | Ep: pct application non-entry in european phase |
Ref document number: 16763217 Country of ref document: EP Kind code of ref document: A1 |