WO2017032788A1 - Laboratory container washing apparatus and system - Google Patents

Laboratory container washing apparatus and system Download PDF

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Publication number
WO2017032788A1
WO2017032788A1 PCT/EP2016/069960 EP2016069960W WO2017032788A1 WO 2017032788 A1 WO2017032788 A1 WO 2017032788A1 EP 2016069960 W EP2016069960 W EP 2016069960W WO 2017032788 A1 WO2017032788 A1 WO 2017032788A1
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
conduit
fluid delivery
manifold
support
Prior art date
Application number
PCT/EP2016/069960
Other languages
French (fr)
Inventor
Philip Roper
John J. Smith
Daniel C. HANSEN
Rose ESCALANTE
Original Assignee
Ventana Medical Systems, Inc.
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Medical Systems, Inc., F. Hoffmann-La Roche Ag filed Critical Ventana Medical Systems, Inc.
Publication of WO2017032788A1 publication Critical patent/WO2017032788A1/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/28Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by splash, spray, or jet application, with or without soaking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L13/00Cleaning or rinsing apparatus
    • B01L13/02Cleaning or rinsing apparatus for receptacle or instruments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/028Modular arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent

Definitions

  • washing of such bottles and containers is a time consuming process that is generally performed manually, where each bottle or container is filled with a washing fluid, shaken or agitated, and emptied. This process is repeated multiple times to ensure the cleanliness of the bottle or container. Not only is this manual process time consuming, but it can lead to workplace injuries and repetitive motion stress injuries.
  • an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source.
  • the apparatus comprises between 1 and 10 fluid delivery members.
  • the apparatus comprises between 2 and 8 fluid delivery members.
  • the apparatus comprises between 3 and 7 fluid delivery members.
  • the apparatus further comprises at least one support conduit having a fluid inlet, wherein the support conduit is in fluidic communication with the manifold and the aqueous fluid source.
  • the support conduit further comprises at least one inlet valve positioned near the fluid inlet to regulate the flow of fluid through the support conduit.
  • the apparatus comprises two support conduits. In some embodiments, a first of the two support conduits is attached to and in fluidic communication with a first end of the manifold and a second of the two support conduits is attached to and in fluidic communication with a second end of the manifold, wherein each of the support conduits are arranged parallel to each other and perpendicular to the manifold.
  • the apparatus further comprises at least one cross-member bridging the support conduits or other apparatus components.
  • the fluid delivery members comprise at least one valve to regulate fluid flow between the interconnected fluid delivery members.
  • the at least one valve is electrically actuated.
  • the delivery conduit comprises at least one delivery valve to regulate fluid flow to the nozzle.
  • the delivery valve is electrically actuated.
  • the manifold is comprised of modular fluid delivery members.
  • a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, the apparatus further comprising at least one support conduit having a fluid inlet, wherein the support conduit is in fluidic communication with the manifold and the fluid source, and where the support conduit further comprises at least one inlet valve positioned near the fluid inlet to regulate the flow of fluid through the support conduit, and (b) a timer, wherein the timer controls an operation of the inlet valve.
  • a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with an aqueous fluid source, (b) a pump, and (c) a timer, wherein the timer operably controls the pump to regulate fluid flow to the apparatus.
  • the system may also comprise one or more valves which may be in communication with the pump and/or the timer, or control module.
  • a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with an aqueous fluid source, (b) one or more valves and/or a pump, and (c) a computer in communication with the one or more valves and/or the pump.
  • the computer is in communication with both the one or more valves and the pump.
  • the system further comprises one or more sensors, wherein the computer is in communication with the one or more sensors.
  • a method of washing containers comprising placing a container in communication with a delivery conduit and/or nozzle of an apparatus for washing containers, wherein the apparatus for washing containers comprises a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into the container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, and initiating a flow of fluid through the apparatus for a predetermined period of time (e.g. about 10 minutes) or until a pre-determined volume of fluid is passed through the apparatus (e.g. about 50L) or each fluid delivery member (e.g. between about 4L and about 8L).
  • the method further comprises the step of regulating a fluid flow through the apparatus.
  • the step of regulating the fluid flow is achieved by controlling one or more valves.
  • the apparatus of the present disclosure allows (1) the washing of a plurality of containers simultaneously; (2) using less fluid as compared within prior art washing systems; (3) where washing is accomplished in less time as compared to prior art methods; and (4) with a reduced chance of injury.
  • Figure 1 illustrates a first embodiment of an apparatus for washing containers comprising a plurality of fluid delivery members, a manifold, and conduits.
  • Figure 2 illustrates a second embodiment of an apparatus for washing containers comprising a plurality of modular fluid delivery members, a manifold, and conduits.
  • Figure 3 illustrates another embodiment of an apparatus for washing containers comprising a plurality of fluid delivery members, a manifold, and conduits, where the containers are shown in communication or in engagement with the apparatus.
  • Figure 4 illustrates a modular component, namely a fluid delivery member, which may be used to construct a manifold or an apparatus of the present disclosure.
  • Figure 5 illustrates a component for engaging and washing large or oversized containers.
  • Figures 6A and 6B illustrate alternate arrangements of fluid delivery members, where the fluid delivery members are arranged in a parallel fashion, and there the solid lines indicate conduits for the delivery of fluid to the fluid delivery members
  • Figure 7 illustrates the washing apparatus in communication with a computer system.
  • the present disclosure is directed to an apparatus and method for facilitating the washing of containers, such as those used in the laboratory setting.
  • the apparatus of the present disclosure is directed to a series of interconnected conduits and fluid delivery members for transferring a fluid to a nozzle, whereby the fluid may be dispersed from the nozzle to facilitate washing of an interior space of a container.
  • the apparatus may comprise one or more valves to regulate fluid flow throughout the apparatus.
  • the apparatus may also be part of a system which comprises one or more of timers, sensors, pumps, a control module, and/or a computer. The apparatus of the present disclosure may thus be controlled manually or may be automated.
  • the containers are those used in the laboratory setting and contain various chemicals, solutions, and/or reagents.
  • Examples of containers include carboys, 3L bottles and 6L bottles.
  • the containers generally have a volume ranging between about 1L to about 50L.
  • Containers suitable for use herein may be made out of any material, including but not limited to plastic (polymers, copolymers, polymer blends, copolymer blends), silicones, composites, fiberglass, metal, Pyrex®, and glass etc.
  • the containers may comprise an opening through which a delivery conduit and nozzle may be inserted to facilitate washing of an interior space of the container (see Figure 3 herein).
  • the containers may have any size or shape, and the container's opening may have any diameter.
  • Figure 1 depicts a first non-limiting embodiment of an apparatus 1 of the present disclosure comprising an array of interconnected fluid delivery members 50A.
  • Each fluid delivery member 50A comprises a nozzle 10 and a delivery conduit 40.
  • the delivery conduit 40 comprises at least one valve 15 for regulating fluid flow (or pressure) to the nozzle 10.
  • the fluid delivery members are directly connected to each other, while in other embodiments they are connected through interconnect conduits 62.
  • the support conduits 60 are arranged parallel to each other but perpendicular to the manifold 80.
  • conduits 60 and 61 are attached to the manifold with interconnect conduits 62.
  • the conduits 60 and 61 are constructed from two or more conduit segments 63, where each conduit segment is joined with an interconnect conduit 62.
  • any support conduit 60 or 61, conduit segment 63, or interconnect conduit 62 may comprise one or more valves (manual or electrically actuated) to regulate fluid flow through that conduit piece.
  • conduit segment 63 further comprises an additional port, which may be used to deliver a different fluid into the apparatus than that introduced at the inlet 30.
  • the additional port allows a second fluid to mix with a primary fluid.
  • a disinfectant or decontamination fluid may be introduced in a concentrated form and allowed to mix with the fluid introduced at inlet 30 such that a fluid mixture, having a certain concentration, may be dispersed from the nozzles.
  • the amount of fluid entering from the port may be separately regulated so as to vary the amount of fluid that enters from that location and thus the overall concentration of the mixture introduced into the system.
  • the fluid introduced at the port is reduced over time, e.g.
  • the manifold may have any length, but generally will be sized to fit the width of a sink or other wash basin. In some embodiments, the manifold ranges from between about 16 inches (40.64 cm) to about 36 inches (91.44 cm) in length.
  • the support conduits like the manifold, may have any length and are generally sized to fit the depth of a sink or other wash basin. In some embodiments, the support conduits range in size from about 8 inches (20.32 cm) to about 24 inches (60.96 cm).
  • additional structure is incorporated into the apparatus such that the manifold, fluid delivery members, and containers (see Figure 3) are posited over the sink or wash basin, and structural members (which may be in fluidic communication with the apparatus) are positioned on a counter or laboratory bench top to support and/or suspend the apparatus.
  • a first support conduit 60 terminates at a fluid inlet 30 which is in fluidic communication with a fluid source.
  • the fluid inlet 30 may comprise a fitting for coupling to tubing or other conduits such that the apparatus may be connected to a fluid source (or another apparatus, e.g. an upstream washing apparatus).
  • the inlet may also comprise a valve 31 so as to regulate fluid fluid from the inlet.
  • a second support conduit 61 terminates with an end member 35.
  • the end member 35 may be a cap that maintains fluid pressure throughout the apparatus 1.
  • the end member 35 may comprise a valve to facilitate the discharge of fluid from the apparatus or to regulate pressure or fluid flow.
  • the end member may comprise a fitting which allows it to couple to another tube or conduit so that multiple washing apparatuses 1 or 2 (or the apparatus depicted in Figure 5) may be linked together.
  • the apparatus of the present disclosure may comprise more than one inlet (e.g. so as to provide a mixture of different fluids from different sources), and any inlet may be provided at any part of the apparatus.
  • a fluid enters the support conduit 60 through inlet 30.
  • the fluid is then transferred from the support conduit 60 to the manifold 80.
  • the fluid may enter each fluid delivery member 50A.
  • the fluid enters the delivery conduit 40 and is dispersed from nozzle 10.
  • Figure 1 depicts the apparatus 1 as comprising seven fluid delivery members 50A, the apparatus 1 may have any number of fluid delivery members. In some embodiments, the number of fluid delivery members range from between 1 to 12. In other embodiments, the number of fluid delivery members ranges from between 2 to 8.
  • the fluid delivery members 50A of Figure 1 are fixed in position. While Figure 1 depicts that each fluid delivery member 50A is arranged at a 90 degree angle relative to the plane of manifold 80 and support conduits 60 and 61, the fluid delivery members 50A may be independently set at any angle relative to the plane (x,y), so as to accommodate containers having different shapes or having openings at different positions. For example, three of the fluid delivery members may be oriented such that they are positioned at a 90 degree angle relative to the plane of the manifold, while three other fluid delivery members may be oriented such that they are positioned at a 70 degree angle relative to the plane of the transfer conduit.
  • Figure 2 depicts a second non- limiting embodiment of an apparatus 2 of the present disclosure, again comprising an array of interconnected fluid delivery members 50B.
  • Each fluid delivery member 50B comprises a nozzle 10, a delivery conduit 40, and optionally a valve 15, including a pressure regulating valve.
  • the interconnected fluid delivery members 50B together constitute manifold 80 which, together with delivery conduits 40 and nozzles 10, is in fluidic communication with two support conduits
  • the fluid delivery members 50B may be spaced at regular intervals from each other or, alternatively, each may be spaced at different intervals from each other.
  • a first support conduit As with the embodiment depicted in Figure 1 , a first support conduit
  • a second support conduit 61 terminates at a fluid inlet 30, which is in fluidic communication with a fluid source.
  • a second support conduit 61 terminates with an end member, which may comprise a valve, a fitting, and/or a cap.
  • an aqueous fluid enters the support conduit 60 through inlet 30.
  • the aqueous fluid is then transferred from the support conduit 60 to the manifold 80, where it enters the delivery conduits 40 and is dispersed from nozzles 10.
  • the fluid delivery members 50B are rotatable around the axis of the manifold.
  • each fluid delivery member 50B is arranged at a 90 degree angle relative to the plane of the manifold 80 and support conduits 60
  • the fluid delivery members 50B may be independently set (and dynamically changed) at any angle relative to the plane (x,y), so as to accommodate containers having different shapes or having openings at different positions.
  • three of the fluid delivery members may be oriented such that they are positioned at a 90 degree angle relative to the plane of the manifold, while three other fluid delivery members may be oriented such that they are positioned at a 60 degree angle relative to the plane of the transfer conduit.
  • the apparatus depicted in Figures 1 and 2 further comprises at least one cross- member 20.
  • the cross-member 20 is believed to increase the rigidity of the apparatus such that the apparatus may support the weight of containers placed thereon or to help support the conduits.
  • the cross-member is arranged such that it bridges support conduits 60 and 61.
  • the cross-member 20 may be any rigid support, brace, pipe, or tube that connects the two opposing support conduits 60 and 61 of the apparatus.
  • the cross-member 20 is comprised of a plastic, metal, or composite bar that may be solid or hollow and which is connected to the conduit via a fastener or clamp (see, for example, Figure 2).
  • the cross-member 20 is itself a conduit and is in fluidic communication with support conduits 60 and 61, by way of an interconnect conduit
  • This type of cross-member may contain a valve to regulate fluid flow.
  • the cross-member 20 is adjustable, such that when modular fluid delivery members (see Figure 4) are assembled into a manifold, a single cross-member may be used to accommodate many different configurations.
  • the cross- member is a telescoping support or brace whose size may be adjusted dynamically.
  • any of the conduits or fluid delivery members may be further reinforced with supports or braces to introduce rigidity into the apparatus and to facilitate movement of the apparatus.
  • Figure 3 depicts a third embodiment of the present disclosure, comprising the apparatus depicted within Figure 2.
  • Figure 3 illustrates the placement of differently sized containers 100 and 110 onto the apparatus.
  • the apparatus depicted in Figure 3 may be constructed so as to accommodate any number of containers in any configuration, and to accommodate any container having any volume, shape, size, or weight. While not illustrated in Figure 3, each of the containers 100 and 110 have an opening through which the delivery conduit 40 (and nozzle 10) is inserted.
  • the aqueous fluid is delivered from nozzles 10 to facilitate delivery of the fluid to the interior space of the containers.
  • the cross-member 20 may be utilized to support the various containers installed onto the apparatus.
  • Figure 4 illustrates a fluid delivery member 50B having a delivery conduit 40, a nozzle 10, and a valve 15.
  • the fluid delivery member member 50B comprises a junction inlet 51 and a junction outlet 53 such that the fluid delivery member 50B may be connected to other fluid delivery members (fixed or rotatable), conduits, interconnects, "quick connects", or spacers to form a manifold comprising a series of interconnected fluid delivery members.
  • the modular fluid delivery member 50B allows for one of skill in the art to assemble a washing apparatus having any desired number of fluid delivery members to facilitate washing of any desired number of containers and to fit any desired workspace (e.g. a sink or other laboratory basin).
  • FIG. 5 illustrates an alternate embodiment of a washing apparatus which is configured to accommodate larger sized containers, such as those containers having a size of 20L or greater (e.g. carboys).
  • the washing apparatus of Figure 5 comprises an inlet 30 (and an optional valve 31) which is in f uidic communication, by way of an interconnect conduit 62, with conduits 65 and 70.
  • a delivery conduit 40 comprising a nozzle 10, is connected to conduit 70 and in fluidic communication with conduits 65 and 70 such that an aqueous fluid may be delivered through the inlet 30 and to the nozzle 10.
  • the delivery conduit comprises an optional valve 15 to regulate fluid flow to the nozzle 10.
  • the conduit 70 comprises two end members 35.
  • the end member 35 may be a cap that maintains fluid pressure throughout the apparatus 3.
  • the end member 35 may comprise a valve to facilitate the discharge of fluid from the apparatus.
  • the end member may comprise a fitting which allows it to couple to another tube or conduit so that multiple washing apparatuses 3 may be linked together.
  • each fluid delivery member may be connected in a "parallel" arrangement as depicted in Figures 6 A and 6B.
  • the conduits and fluid delivery members may independently have any size and shape.
  • the delivery conduits 40 may have a size ranging from between 0.75 inches (1.905 cm) and 6.5 inches (16.51 cm) in length.
  • the delivery conduits may have a diameter ranging from between 0.25 inches (0.635 cm) to about 1.5 inches (3.81 cm) and may vary depending on the size of the opening of the container being washed.
  • some delivery conduits may have a first size while other delivery conduits may have a second size (length and/or conduit diameter). Any of the conduits may have any size and one of skill in the art will select an appropriate length of conduit such that fluid delivery members are spaced at desired intervals from each other (e.g.
  • the conduits may have any interior shape or diameter to accommodate different volumes and/or flow rates of aqueous fluid.
  • a cross-section of any conduit may be circular, oval, square, etc.
  • the conduit may have a variable interior diameter that changes as the distance from the inlet increases so as to maintain a constant flow of fluid (and/or pressure) throughout the apparatus.
  • the components of the apparatus of the present disclosure may be constructed of any material.
  • the components are constructed of materials that are resistant to the fluids used in operation of the apparatus.
  • the components are constructed of rust-proof materials or materials which have been treated with rust-proof or rust-resistant coatings.
  • the components are constructed of polymers, polymer blends, copolymers, and co-polymer blends as known to those of ordinary skill in the art.
  • components are constructed from synthetic rubbers, phenol formaldehyde resins, nylons, polyvinyl chloride (PVC or vinyl), polystyrene, polyethylene, polypropylene, polyacrylonitrile, polyvinyl butyral (“PVB”), silicone, polyoxymethylene (“acetal”), acrylonitrile butadiene styrene (“ABS”), and any combination thereof.
  • the fluid delivery members 50A and 50B may contain one or more valves.
  • the fluid delivery members 50A and 50B may contain a valve which regulates fluid flow through the fluid delivery member, to the delivery conduit 40, and/or between interconnected fluid delivery members.
  • regulating fluid flow it is meant that the flow of fluid through the fluid delivery member, and hence the volume of fluid passing through the fluid delivery member, may be reduced or completely stopped.
  • a valve 15 is provided within the delivery conduit 40 to regulate fluid flow or pressure flow directly to nozzle 10.
  • the valves may serve to turn off particular nozzles in a washing apparatus or to scale back the volume of fluid being delivered from any particular nozzle (e.g. to accommodate containers having larger or smaller sizes and volumes).
  • the valves employed may be manually operable, self-regulating, or electronically actuated.
  • a valve operated by a timer is inserted between the inlet 30 and the fluid source so as to reduce or stop fluid flow through the apparatus after a pre-determined amount of time has passed. It is believed that incorporation of such a valve and timer means allows for the unsupervised use of the washing apparatus and/or prevents the unnecessary waste of aqueous fluid.
  • the timer may be set such that the valve closes after a predetermined period of operation. For example, the timer may command the valve to close after fluid flows through the apparatus for a time period ranging from between about 2 minutes to about 30 minutes. In some embodiments, the time period ranges from about 5 minutes to about 20 minutes.
  • the fluid valve may comprise a built in timer.
  • the apparatus of the present disclosure is connected to a fluid source.
  • the apparatus may be directly connected to a source that provides for fluid flow (e.g. a sink).
  • the apparatus may be connected to a pump or other means to actively deliver fluid to the apparatus while allowing for recirculation of the fluid.
  • the pump may comprise control logic, sensors, or meters which monitor the fluid flow rate and fluid flow volume through the system.
  • the pump may deliver a pre-determined volume of fluid through the apparatus.
  • the pre-determined volume of fluid ranges from between about 10L to about 100L. In other embodiments, the pre-determined volume ranges from between about 15L to about 50L.
  • the fluid for washing is an aqueous fluid.
  • the fluid is distilled and/or deionized water (hereinafter "water”).
  • the fluid is a mixture of water and a surfactant.
  • the fluid is a mixture of water and at least one of an antibacterial agent or an antifungal agent.
  • the fluid is a mixture of water and a disinfectant, such as a quaternary ammonium disinfectant (e.g. Lysol®).
  • the system may be adapted for use of any fluid or solution, whether it is aqueous or non-aqueous (including acidic and basic solutions), and may be further adapted for the use of solvents or solvent systems (including volatile organic solvents) as needed.
  • multiple fluid sources are present and each are in communication (e.g. connected to) the apparatus of the present disclosure.
  • valves may control which fluids are provided to the apparatus and may also regulate the concentration of any fluid provided to the apparatus so that mixtures of fluids (having various concentrations) may be delivered to the containers.
  • the nozzles 10 may contain a sensor whereby the nozzle only dispenses fluid if the sensor detects that a container has been placed over the nozzle 10 and/or delivery conduit 40.
  • the sensor determines that no container has been placed, it sends signals directly to a valve or to a computer or control module that controls the valve to close.
  • the sensor determines that a container has been placed, it sends signals directly to a valve or to a computer or control module that controls the valve to open, and thereby permit fluid flow from the nozzle and into the interior space of the container.
  • a lever arm is used to mechanically open and close valves, where the lever arm is actuated by means of the weight of the bottle or container disposed thereon.
  • the nozzles 10 may be any type of spray nozzle known to those of ordinary skill in the art.
  • the nozzle is selected from the group consisting of plain-orifice nozzles, shaped-orifice nozzles, surface-impingement single-fluid nozzles, pressure-swirl single-fluid spray nozzles, solid-cone single-fluid nozzles, and compound nozzles.
  • the nozzles are rotating stream nozzles or pop-up nozzles, as known to those of ordinary skill in the art.
  • the material of construction of the nozzle is selected based on the fluid properties of the fluid that is to be sprayed.
  • Spray nozzles are most commonly fabricated from metals, such as brass, stainless steel, and nickel alloys, but plastics such as polytetrafluoroethylene, polyoxymethylene (acetal), ABS, PVB, and polyvinyl chloride may also used.
  • Each fluid delivery member 50A or 50B may comprise the same or different nozzle.
  • the nozzles spray 360 degrees within the container. In other embodiments, the nozzles spray less than 360 degrees, e.g. 180 degrees, 90 degrees, etc. In other embodiments, the nozzle is selected such that it dispenses fluid with sufficient pressure and coverage such that all surfaces of the interior of a container are sufficiently wetted with fluid.
  • the apparatus may be optionally connected to an air line, such as through a second inlet in one of the conduits, so as to allow filtered air (or an inert gas) to be blown through the apparatus to discharge any remaining water.
  • the apparatus may be configured such that after a cleaning operation is performed with an aqueous fluid, air is pumped through the apparatus, through the nozzles, and into the containers to facilitate removal of excess aqueous fluid or drying of the containers.
  • the apparatus may be operated manually or may be automated.
  • the apparatus may be connected to computer, programmable controller (e.g. a programmable logic controller, "PLC"), custom-build controllers, or other control modules (herein “computer”) that controls a pump (and pump parameters).
  • PLC programmable logic controller
  • computer may be programmed to control the operation of those values, where each valve may be controlled independently.
  • a user may program the computer to provide for a certain pre-determined flow rate or quantity of water to flow through the entire apparatus or any individual fluid delivery member, delivery conduit, and/or or nozzle, such as by regulating fluid flow at the inlet, at a pump, or any of the valves.
  • the parameters for operation may be based on the fluid being introduced into the apparatus, the size of the containers, the cleanliness of the containers, etc.
  • the system allows for the remote monitoring and/or the remote control of the apparatus and any connected components (e.g. valves, timers, etc.).
  • a representative system 100 for implementing the invention includes a washing apparatus 120, and computer device 130, which may be a general-purpose or special-purpose computer.
  • computer device 130 may be a personal computer, a notebook computer, a personal digital assistant ("PDA") or other hand- held device, a workstation, a minicomputer, a mainframe, a supercomputer, a multi-processor system, a network computer, a processor-based consumer electronic device, or the like.
  • PDA personal digital assistant
  • Computer device 130 may or may not include system bus. If so, a system bus may be configured to connect various components thereof and to enable data to be exchanged between two or more components.
  • a system bus may include one of a variety of bus structures including a memory bus or memory controller, a peripheral bus, or a local bus that uses any of a variety of bus architectures.
  • Typical components connected by system bus include processing system 140 and memory.
  • Other typical computer components may include one or more mass storage device interfaces, input interfaces, output interfaces 150, and network interfaces.
  • Components unique to the present invention that may be connected by bus to those just mentioned or to one another include, one or more valve components, one or more pumps, and one or more sensors (e.g. optical, laser, liquid sensors, etc.).
  • the system 100, or its individual components, may be connected to a network 110.
  • Processing system includes one or more processors, such as a central processor and optionally one or more other processors designed to perform a particular function or task, such as the learning and storing of a pre-determined sprinkler function during a teach mode. It is typically a processing system that executes the instructions provided on computer readable media, such as on memory, a magnetic hard disk, a removable magnetic disk, a magnetic cassette, an optical disk. Processing system may also be operable with a remote computer device through a communication connection 40, which remote computer device may also be a computer readable media such as a remote memory storage device.
  • Memory includes one or more computer readable media that may be configured to include or includes thereon data or instructions for manipulating data, and may be accessed by processing system through system bus.
  • Memory may include, for example, ROM, used to permanently store information, and/or RAM, used to temporarily store information.
  • ROM may include a basic input/output system ("BIOS") having one or more routines that are used to establish communication, such as during startup of computer device.
  • BIOS basic input/output system
  • RAM may include one or more program modules, such as one or more operating systems, application programs, and/or program data.
  • One or more mass storage device interfaces may be used to connect one or more mass storage devices to system bus.
  • the mass storage devices may be incorporated into or may be peripheral to computer device and allow computer device to retain large amounts of data.
  • one or more of the mass storage devices may be removable from computer device. Examples of mass storage devices include hard disk drives, magnetic disk drives, tape drives and optical disk drives.
  • a mass storage device may read from and/or write to a magnetic hard disk, a removable magnetic disk, a magnetic cassette, an optical disk, or another computer readable medium.
  • Mass storage devices and their corresponding computer readable media provide nonvolatile storage of data and/or executable instructions that may include one or more program modules such as an operating system, one or more application programs, other program modules, or program data. Such executable instructions are examples of program code means for implementing steps for methods disclosed herein.
  • One or more input interfaces may be employed to enable a user to enter data and/or instructions to computer device through one or more corresponding input devices.
  • One or more output interfaces may be employed to connect one or more corresponding output devices to system bus. Examples of output devices include a monitor or display screen and the like.
  • a method of washing containers comprising placing a container in communication with a delivery conduit and/or nozzle of an apparatus for washing containers, wherein the apparatus for washing containers comprises a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into the container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, and initiating a flow of fluid through the apparatus for a predetermined period of time (e.g. about 10 minutes) or until a pre-determined volume of fluid is passed through the apparatus (e.g. about 50L) or each fluid delivery member (e.g. between about 4L and about 8L).
  • a predetermined period of time e.g. about 10 minutes
  • a pre-determined volume of fluid is passed through the apparatus
  • each fluid delivery member e.g. between about 4L and about 8L.
  • the method further comprises the step of regulating a fluid flow through the apparatus.
  • the step of regulating the fluid flow is achieved by controlling one or more valves.
  • a cleaning fluid e.g. a decontaminating fluid
  • the cleaning fluid is first introduced into the containers, either manually or through use of the disclosed apparatus. Then, the cleaning fluid is washed from the containers by means of the apparatus (or system) and method described herein.
  • a single fluid is provided to the apparatus.
  • multiple different fluids or the same fluid having a different concentration of one or more components
  • the different fluids are introduced at different sections of the apparatus or at different times.
  • a second concentrated fluid may be introduced at a port different than the inlet valve 30, and the concentrated fluid may be allowed to mix with a first fluid introduced at inlet 30.
  • the concentration of the mixed fluid may be varied based on the amount of second concentrated fluid introduced or metered into the apparatus.

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Abstract

The present disclosure is directed to an apparatus and method for facilitating the washing of containers, such as those used in the laboratory setting. In general, the apparatus of the present disclosure is directed to a series of interconnected conduits for transferring an aqueous fluid to a nozzle, whereby the fluid may be dispersed from the nozzle to facilitate washing of an interior space of a container.

Description

LABORATORY CONTAINER WASHING APPARATUS AND SYSTEM
BACKGROUND
Laboratory bottles and other containers, especially those used for instrumentation, must be washed before and/or after use, or periodically for decontamination.
Washing of such bottles and containers is a time consuming process that is generally performed manually, where each bottle or container is filled with a washing fluid, shaken or agitated, and emptied. This process is repeated multiple times to ensure the cleanliness of the bottle or container. Not only is this manual process time consuming, but it can lead to workplace injuries and repetitive motion stress injuries.
BRIEF SUMMARY OF THE INVENTION
In one aspect of the present disclosure is an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source. In some embodiments, the apparatus comprises between 1 and 10 fluid delivery members. In some embodiments, the apparatus comprises between 2 and 8 fluid delivery members. In some embodiments, the apparatus comprises between 3 and 7 fluid delivery members.
In some embodiments, the apparatus further comprises at least one support conduit having a fluid inlet, wherein the support conduit is in fluidic communication with the manifold and the aqueous fluid source. In some embodiments, the support conduit further comprises at least one inlet valve positioned near the fluid inlet to regulate the flow of fluid through the support conduit. In some embodiments, the apparatus comprises two support conduits. In some embodiments, a first of the two support conduits is attached to and in fluidic communication with a first end of the manifold and a second of the two support conduits is attached to and in fluidic communication with a second end of the manifold, wherein each of the support conduits are arranged parallel to each other and perpendicular to the manifold. In some embodiments, the apparatus further comprises at least one cross-member bridging the support conduits or other apparatus components. In some embodiments, the fluid delivery members comprise at least one valve to regulate fluid flow between the interconnected fluid delivery members. In some embodiments, the at least one valve is electrically actuated. In some embodiments, the delivery conduit comprises at least one delivery valve to regulate fluid flow to the nozzle. In some embodiments, the delivery valve is electrically actuated. In some embodiments, the manifold is comprised of modular fluid delivery members.
In another aspect of the present disclosure is a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, the apparatus further comprising at least one support conduit having a fluid inlet, wherein the support conduit is in fluidic communication with the manifold and the fluid source, and where the support conduit further comprises at least one inlet valve positioned near the fluid inlet to regulate the flow of fluid through the support conduit, and (b) a timer, wherein the timer controls an operation of the inlet valve.
In another aspect of the present disclosure is a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with an aqueous fluid source, (b) a pump, and (c) a timer, wherein the timer operably controls the pump to regulate fluid flow to the apparatus. The system may also comprise one or more valves which may be in communication with the pump and/or the timer, or control module.
In another aspect of the present disclosure is a system for washing containers comprising (a) an apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with an aqueous fluid source, (b) one or more valves and/or a pump, and (c) a computer in communication with the one or more valves and/or the pump. In some embodiments, the computer is in communication with both the one or more valves and the pump. In some embodiments, the system further comprises one or more sensors, wherein the computer is in communication with the one or more sensors. In another aspect is a method of washing containers comprising placing a container in communication with a delivery conduit and/or nozzle of an apparatus for washing containers, wherein the apparatus for washing containers comprises a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into the container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, and initiating a flow of fluid through the apparatus for a predetermined period of time (e.g. about 10 minutes) or until a pre-determined volume of fluid is passed through the apparatus (e.g. about 50L) or each fluid delivery member (e.g. between about 4L and about 8L). In some embodiments, the method further comprises the step of regulating a fluid flow through the apparatus. In some embodiments, the step of regulating the fluid flow is achieved by controlling one or more valves.
The apparatus of the present disclosure allows (1) the washing of a plurality of containers simultaneously; (2) using less fluid as compared within prior art washing systems; (3) where washing is accomplished in less time as compared to prior art methods; and (4) with a reduced chance of injury.
BRIEF DESCRIPTION OF THE DRAWINGS
Non-limiting and non-exhaustive embodiments are described with reference to the following drawings. The same reference numerals refer to like parts or acts throughout the various views, unless otherwise specified.
Figure 1 illustrates a first embodiment of an apparatus for washing containers comprising a plurality of fluid delivery members, a manifold, and conduits.
Figure 2 illustrates a second embodiment of an apparatus for washing containers comprising a plurality of modular fluid delivery members, a manifold, and conduits. Figure 3 illustrates another embodiment of an apparatus for washing containers comprising a plurality of fluid delivery members, a manifold, and conduits, where the containers are shown in communication or in engagement with the apparatus.
Figure 4 illustrates a modular component, namely a fluid delivery member, which may be used to construct a manifold or an apparatus of the present disclosure.
Figure 5 illustrates a component for engaging and washing large or oversized containers.
Figures 6A and 6B illustrate alternate arrangements of fluid delivery members, where the fluid delivery members are arranged in a parallel fashion, and there the solid lines indicate conduits for the delivery of fluid to the fluid delivery members
(boxes).
Figure 7 illustrates the washing apparatus in communication with a computer system.
DETAILED DESCRIPTION The present disclosure is directed to an apparatus and method for facilitating the washing of containers, such as those used in the laboratory setting. In general, the apparatus of the present disclosure is directed to a series of interconnected conduits and fluid delivery members for transferring a fluid to a nozzle, whereby the fluid may be dispersed from the nozzle to facilitate washing of an interior space of a container. The apparatus may comprise one or more valves to regulate fluid flow throughout the apparatus. The apparatus may also be part of a system which comprises one or more of timers, sensors, pumps, a control module, and/or a computer. The apparatus of the present disclosure may thus be controlled manually or may be automated. In some embodiments, the containers are those used in the laboratory setting and contain various chemicals, solutions, and/or reagents. Examples of containers include carboys, 3L bottles and 6L bottles. The containers generally have a volume ranging between about 1L to about 50L. Containers suitable for use herein may be made out of any material, including but not limited to plastic (polymers, copolymers, polymer blends, copolymer blends), silicones, composites, fiberglass, metal, Pyrex®, and glass etc. The containers may comprise an opening through which a delivery conduit and nozzle may be inserted to facilitate washing of an interior space of the container (see Figure 3 herein). The containers may have any size or shape, and the container's opening may have any diameter.
Figure 1 depicts a first non-limiting embodiment of an apparatus 1 of the present disclosure comprising an array of interconnected fluid delivery members 50A. Each fluid delivery member 50A comprises a nozzle 10 and a delivery conduit 40.
In some embodiments, the delivery conduit 40 comprises at least one valve 15 for regulating fluid flow (or pressure) to the nozzle 10.
The interconnected fluid delivery members 50A together constitute manifold 80 which, together with delivery conduits 40 and nozzles 10, is in fluidic communication with two support conduits 60 and 61. The fluid delivery members
50A may be spaced at regular intervals from each other or, alternatively, each may be spaced at different intervals from each other. In some embodiments, the fluid delivery members are directly connected to each other, while in other embodiments they are connected through interconnect conduits 62. The support conduits 60 are arranged parallel to each other but perpendicular to the manifold 80. The conduits
60 and 61 are attached to the manifold with interconnect conduits 62. In some embodiments, the conduits 60 and 61 are constructed from two or more conduit segments 63, where each conduit segment is joined with an interconnect conduit 62. The skilled artisan will appreciate that any support conduit 60 or 61, conduit segment 63, or interconnect conduit 62 may comprise one or more valves (manual or electrically actuated) to regulate fluid flow through that conduit piece.
In some embodiments, conduit segment 63 further comprises an additional port, which may be used to deliver a different fluid into the apparatus than that introduced at the inlet 30. In some embodiments, the additional port allows a second fluid to mix with a primary fluid. For example, and as discussed further herein, a disinfectant or decontamination fluid may be introduced in a concentrated form and allowed to mix with the fluid introduced at inlet 30 such that a fluid mixture, having a certain concentration, may be dispersed from the nozzles. The amount of fluid entering from the port may be separately regulated so as to vary the amount of fluid that enters from that location and thus the overall concentration of the mixture introduced into the system. In some embodiments, the fluid introduced at the port is reduced over time, e.g. tapered gradually or reduced in a step-wise manner. The manifold may have any length, but generally will be sized to fit the width of a sink or other wash basin. In some embodiments, the manifold ranges from between about 16 inches (40.64 cm) to about 36 inches (91.44 cm) in length. The support conduits, like the manifold, may have any length and are generally sized to fit the depth of a sink or other wash basin. In some embodiments, the support conduits range in size from about 8 inches (20.32 cm) to about 24 inches (60.96 cm). In some embodiments, additional structure is incorporated into the apparatus such that the manifold, fluid delivery members, and containers (see Figure 3) are posited over the sink or wash basin, and structural members (which may be in fluidic communication with the apparatus) are positioned on a counter or laboratory bench top to support and/or suspend the apparatus.
A first support conduit 60 terminates at a fluid inlet 30 which is in fluidic communication with a fluid source. The fluid inlet 30 may comprise a fitting for coupling to tubing or other conduits such that the apparatus may be connected to a fluid source (or another apparatus, e.g. an upstream washing apparatus). The inlet may also comprise a valve 31 so as to regulate fluid fluid from the inlet. A second support conduit 61 terminates with an end member 35. In some embodiments, the end member 35 may be a cap that maintains fluid pressure throughout the apparatus 1. In some embodiments, the end member 35 may comprise a valve to facilitate the discharge of fluid from the apparatus or to regulate pressure or fluid flow. In other embodiments, the end member may comprise a fitting which allows it to couple to another tube or conduit so that multiple washing apparatuses 1 or 2 (or the apparatus depicted in Figure 5) may be linked together. The skilled artisan will recognize that the apparatus of the present disclosure may comprise more than one inlet (e.g. so as to provide a mixture of different fluids from different sources), and any inlet may be provided at any part of the apparatus.
In operation, a fluid enters the support conduit 60 through inlet 30. The fluid is then transferred from the support conduit 60 to the manifold 80. From the manifold 80, the fluid may enter each fluid delivery member 50A. From the fluid delivery member 5 OA, the fluid enters the delivery conduit 40 and is dispersed from nozzle 10.
While Figure 1 depicts the apparatus 1 as comprising seven fluid delivery members 50A, the apparatus 1 may have any number of fluid delivery members. In some embodiments, the number of fluid delivery members range from between 1 to 12. In other embodiments, the number of fluid delivery members ranges from between 2 to 8.
The fluid delivery members 50A of Figure 1 are fixed in position. While Figure 1 depicts that each fluid delivery member 50A is arranged at a 90 degree angle relative to the plane of manifold 80 and support conduits 60 and 61, the fluid delivery members 50A may be independently set at any angle relative to the plane (x,y), so as to accommodate containers having different shapes or having openings at different positions. For example, three of the fluid delivery members may be oriented such that they are positioned at a 90 degree angle relative to the plane of the manifold, while three other fluid delivery members may be oriented such that they are positioned at a 70 degree angle relative to the plane of the transfer conduit.
The embodiment depicted in Figure 2 is similar to that illustrated and described with regard to Figure 1. As such, any components described for the embodiment of Figure 1 may also be applied to the embodiment of Figure 2. Figure 2 depicts a second non- limiting embodiment of an apparatus 2 of the present disclosure, again comprising an array of interconnected fluid delivery members 50B. Each fluid delivery member 50B comprises a nozzle 10, a delivery conduit 40, and optionally a valve 15, including a pressure regulating valve. The interconnected fluid delivery members 50B together constitute manifold 80 which, together with delivery conduits 40 and nozzles 10, is in fluidic communication with two support conduits
60 and 61. The fluid delivery members 50B may be spaced at regular intervals from each other or, alternatively, each may be spaced at different intervals from each other. As with the embodiment depicted in Figure 1 , a first support conduit
61 terminates at a fluid inlet 30, which is in fluidic communication with a fluid source. A second support conduit 61 terminates with an end member, which may comprise a valve, a fitting, and/or a cap. In operation, an aqueous fluid enters the support conduit 60 through inlet 30. The aqueous fluid is then transferred from the support conduit 60 to the manifold 80, where it enters the delivery conduits 40 and is dispersed from nozzles 10. The fluid delivery members 50B are rotatable around the axis of the manifold.
While Figure 2 depicts that each fluid delivery member 50B is arranged at a 90 degree angle relative to the plane of the manifold 80 and support conduits 60, the fluid delivery members 50B may be independently set (and dynamically changed) at any angle relative to the plane (x,y), so as to accommodate containers having different shapes or having openings at different positions. For example, three of the fluid delivery members may be oriented such that they are positioned at a 90 degree angle relative to the plane of the manifold, while three other fluid delivery members may be oriented such that they are positioned at a 60 degree angle relative to the plane of the transfer conduit. The apparatus depicted in Figures 1 and 2 further comprises at least one cross- member 20. The cross-member 20 is believed to increase the rigidity of the apparatus such that the apparatus may support the weight of containers placed thereon or to help support the conduits. The cross-member is arranged such that it bridges support conduits 60 and 61. The cross-member 20 may be any rigid support, brace, pipe, or tube that connects the two opposing support conduits 60 and 61 of the apparatus. In some embodiments, the cross-member 20 is comprised of a plastic, metal, or composite bar that may be solid or hollow and which is connected to the conduit via a fastener or clamp (see, for example, Figure 2). In other embodiments, the cross-member 20 is itself a conduit and is in fluidic communication with support conduits 60 and 61, by way of an interconnect conduit
62, and thus facilitates the transfer of fluid through the apparatus. This type of cross-member may contain a valve to regulate fluid flow. In some embodiments, the cross-member 20 is adjustable, such that when modular fluid delivery members (see Figure 4) are assembled into a manifold, a single cross-member may be used to accommodate many different configurations. In some embodiments, the cross- member is a telescoping support or brace whose size may be adjusted dynamically. The skilled artisan will appreciate that any of the conduits or fluid delivery members, may be further reinforced with supports or braces to introduce rigidity into the apparatus and to facilitate movement of the apparatus. Figure 3 depicts a third embodiment of the present disclosure, comprising the apparatus depicted within Figure 2. Figure 3, however, illustrates the placement of differently sized containers 100 and 110 onto the apparatus. The apparatus depicted in Figure 3 may be constructed so as to accommodate any number of containers in any configuration, and to accommodate any container having any volume, shape, size, or weight. While not illustrated in Figure 3, each of the containers 100 and 110 have an opening through which the delivery conduit 40 (and nozzle 10) is inserted. In operation, the aqueous fluid is delivered from nozzles 10 to facilitate delivery of the fluid to the interior space of the containers. As the fluid is delivered into the container, it washes the interior of the container, and the aqueous fluid, along with any residues present within the container prior to washing, is allowed to drain out of the container opening. Figure 3 also depicts that the cross-member 20 may be utilized to support the various containers installed onto the apparatus.
Figure 4 illustrates a fluid delivery member 50B having a delivery conduit 40, a nozzle 10, and a valve 15. The fluid delivery member member 50B comprises a junction inlet 51 and a junction outlet 53 such that the fluid delivery member 50B may be connected to other fluid delivery members (fixed or rotatable), conduits, interconnects, "quick connects", or spacers to form a manifold comprising a series of interconnected fluid delivery members. The modular fluid delivery member 50B allows for one of skill in the art to assemble a washing apparatus having any desired number of fluid delivery members to facilitate washing of any desired number of containers and to fit any desired workspace (e.g. a sink or other laboratory basin).
Figure 5 illustrates an alternate embodiment of a washing apparatus which is configured to accommodate larger sized containers, such as those containers having a size of 20L or greater (e.g. carboys). The washing apparatus of Figure 5 comprises an inlet 30 (and an optional valve 31) which is in f uidic communication, by way of an interconnect conduit 62, with conduits 65 and 70. A delivery conduit 40, comprising a nozzle 10, is connected to conduit 70 and in fluidic communication with conduits 65 and 70 such that an aqueous fluid may be delivered through the inlet 30 and to the nozzle 10. The delivery conduit comprises an optional valve 15 to regulate fluid flow to the nozzle 10. The conduit 70 comprises two end members 35. In some embodiments, the end member 35 may be a cap that maintains fluid pressure throughout the apparatus 3. In some embodiments, the end member 35 may comprise a valve to facilitate the discharge of fluid from the apparatus. In some embodiments, the end member may comprise a fitting which allows it to couple to another tube or conduit so that multiple washing apparatuses 3 may be linked together.
The fluid delivery members, while depicted as being serially connected to one another in Figures 1, 2, and 3 may also be connected in various other ways as will be appreciated by those of ordinary skill in the art. For example, each fluid delivery member may be connected in a "parallel" arrangement as depicted in Figures 6 A and 6B.
The conduits and fluid delivery members may independently have any size and shape. For example, the delivery conduits 40 may have a size ranging from between 0.75 inches (1.905 cm) and 6.5 inches (16.51 cm) in length. By way of further example, the delivery conduits may have a diameter ranging from between 0.25 inches (0.635 cm) to about 1.5 inches (3.81 cm) and may vary depending on the size of the opening of the container being washed. In some embodiments, some delivery conduits may have a first size while other delivery conduits may have a second size (length and/or conduit diameter). Any of the conduits may have any size and one of skill in the art will select an appropriate length of conduit such that fluid delivery members are spaced at desired intervals from each other (e.g. to accommodate containers having different volumes and/or sizes). The conduits may have any interior shape or diameter to accommodate different volumes and/or flow rates of aqueous fluid. For example, a cross-section of any conduit may be circular, oval, square, etc. The skilled artisan will appreciate that given a constant flow rate at an inlet, the velocity of the aqueous fluid moving through the conduit may be altered based on the interior diameter of the conduit. In some embodiments, the conduit may have a variable interior diameter that changes as the distance from the inlet increases so as to maintain a constant flow of fluid (and/or pressure) throughout the apparatus.
The components of the apparatus of the present disclosure may be constructed of any material. In some embodiments, the components are constructed of materials that are resistant to the fluids used in operation of the apparatus. In other embodiments, the components are constructed of rust-proof materials or materials which have been treated with rust-proof or rust-resistant coatings. In yet other embodiments, the components are constructed of polymers, polymer blends, copolymers, and co-polymer blends as known to those of ordinary skill in the art. In yet further embodiments, components are constructed from synthetic rubbers, phenol formaldehyde resins, nylons, polyvinyl chloride (PVC or vinyl), polystyrene, polyethylene, polypropylene, polyacrylonitrile, polyvinyl butyral ("PVB"), silicone, polyoxymethylene ("acetal"), acrylonitrile butadiene styrene ("ABS"), and any combination thereof. The fluid delivery members 50A and 50B may contain one or more valves. For example, the fluid delivery members 50A and 50B may contain a valve which regulates fluid flow through the fluid delivery member, to the delivery conduit 40, and/or between interconnected fluid delivery members. By "regulating fluid flow" it is meant that the flow of fluid through the fluid delivery member, and hence the volume of fluid passing through the fluid delivery member, may be reduced or completely stopped. In some embodiments, a valve 15 is provided within the delivery conduit 40 to regulate fluid flow or pressure flow directly to nozzle 10. In some embodiments, the valves may serve to turn off particular nozzles in a washing apparatus or to scale back the volume of fluid being delivered from any particular nozzle (e.g. to accommodate containers having larger or smaller sizes and volumes). The valves employed may be manually operable, self-regulating, or electronically actuated.
In some embodiments, a valve operated by a timer (e.g. manual or electronic) is inserted between the inlet 30 and the fluid source so as to reduce or stop fluid flow through the apparatus after a pre-determined amount of time has passed. It is believed that incorporation of such a valve and timer means allows for the unsupervised use of the washing apparatus and/or prevents the unnecessary waste of aqueous fluid. The timer may be set such that the valve closes after a predetermined period of operation. For example, the timer may command the valve to close after fluid flows through the apparatus for a time period ranging from between about 2 minutes to about 30 minutes. In some embodiments, the time period ranges from about 5 minutes to about 20 minutes. In some embodiments, the fluid valve may comprise a built in timer.
The apparatus of the present disclosure is connected to a fluid source. The apparatus may be directly connected to a source that provides for fluid flow (e.g. a sink). Alternatively, the apparatus may be connected to a pump or other means to actively deliver fluid to the apparatus while allowing for recirculation of the fluid. Of course, the skilled artisan will recognize that any number of different fluid pumps may be utilized and regulated to provide the desired fluid flow rate and volume. The pump may comprise control logic, sensors, or meters which monitor the fluid flow rate and fluid flow volume through the system. In some embodiments, the pump may deliver a pre-determined volume of fluid through the apparatus. In some embodiments, the pre-determined volume of fluid ranges from between about 10L to about 100L. In other embodiments, the pre-determined volume ranges from between about 15L to about 50L.
In some embodiments, the fluid for washing is an aqueous fluid. In some embodiments, the fluid is distilled and/or deionized water (hereinafter "water"). In other embodiments, the fluid is a mixture of water and a surfactant. In yet other embodiments, the fluid is a mixture of water and at least one of an antibacterial agent or an antifungal agent. In other embodiments, the fluid is a mixture of water and a disinfectant, such as a quaternary ammonium disinfectant (e.g. Lysol®). The skilled artisan will also recognize that the system may be adapted for use of any fluid or solution, whether it is aqueous or non-aqueous (including acidic and basic solutions), and may be further adapted for the use of solvents or solvent systems (including volatile organic solvents) as needed. In some embodiments, multiple fluid sources are present and each are in communication (e.g. connected to) the apparatus of the present disclosure. In these embodiments, valves may control which fluids are provided to the apparatus and may also regulate the concentration of any fluid provided to the apparatus so that mixtures of fluids (having various concentrations) may be delivered to the containers.
In another embodiment, the nozzles 10 may contain a sensor whereby the nozzle only dispenses fluid if the sensor detects that a container has been placed over the nozzle 10 and/or delivery conduit 40. When the sensor determines that no container has been placed, it sends signals directly to a valve or to a computer or control module that controls the valve to close. Likewise, when the sensor determines that a container has been placed, it sends signals directly to a valve or to a computer or control module that controls the valve to open, and thereby permit fluid flow from the nozzle and into the interior space of the container. In this way, containers may be installed and removed from the apparatus while other containers are being washed, and this allows for increased runtime and efficiency. In some embodiments, rather than utilize an electronic sensor, a lever arm is used to mechanically open and close valves, where the lever arm is actuated by means of the weight of the bottle or container disposed thereon.
The nozzles 10 may be any type of spray nozzle known to those of ordinary skill in the art. In some embodiments, the nozzle is selected from the group consisting of plain-orifice nozzles, shaped-orifice nozzles, surface-impingement single-fluid nozzles, pressure-swirl single-fluid spray nozzles, solid-cone single-fluid nozzles, and compound nozzles. In some embodiments, the nozzles are rotating stream nozzles or pop-up nozzles, as known to those of ordinary skill in the art. The material of construction of the nozzle is selected based on the fluid properties of the fluid that is to be sprayed. Spray nozzles are most commonly fabricated from metals, such as brass, stainless steel, and nickel alloys, but plastics such as polytetrafluoroethylene, polyoxymethylene (acetal), ABS, PVB, and polyvinyl chloride may also used. Each fluid delivery member 50A or 50B may comprise the same or different nozzle. In some embodiments, the nozzles spray 360 degrees within the container. In other embodiments, the nozzles spray less than 360 degrees, e.g. 180 degrees, 90 degrees, etc. In other embodiments, the nozzle is selected such that it dispenses fluid with sufficient pressure and coverage such that all surfaces of the interior of a container are sufficiently wetted with fluid.
In some embodiments, the apparatus may be optionally connected to an air line, such as through a second inlet in one of the conduits, so as to allow filtered air (or an inert gas) to be blown through the apparatus to discharge any remaining water. In other embodiments, the apparatus may be configured such that after a cleaning operation is performed with an aqueous fluid, air is pumped through the apparatus, through the nozzles, and into the containers to facilitate removal of excess aqueous fluid or drying of the containers.
The apparatus may be operated manually or may be automated. For example, the apparatus may be connected to computer, programmable controller (e.g. a programmable logic controller, "PLC"), custom-build controllers, or other control modules (herein "computer") that controls a pump (and pump parameters). In addition, where the apparatus comprises one or more electronically controlled valves, the computer may be programmed to control the operation of those values, where each valve may be controlled independently. In other embodiments, a user may program the computer to provide for a certain pre-determined flow rate or quantity of water to flow through the entire apparatus or any individual fluid delivery member, delivery conduit, and/or or nozzle, such as by regulating fluid flow at the inlet, at a pump, or any of the valves. The skilled artisan will recognize that the parameters for operation may be based on the fluid being introduced into the apparatus, the size of the containers, the cleanliness of the containers, etc. In some embodiments, the system allows for the remote monitoring and/or the remote control of the apparatus and any connected components (e.g. valves, timers, etc.).
A representative system 100 for implementing the invention includes a washing apparatus 120, and computer device 130, which may be a general-purpose or special-purpose computer. For example, computer device 130 may be a personal computer, a notebook computer, a personal digital assistant ("PDA") or other hand- held device, a workstation, a minicomputer, a mainframe, a supercomputer, a multi-processor system, a network computer, a processor-based consumer electronic device, or the like.
Computer device 130 may or may not include system bus. If so, a system bus may be configured to connect various components thereof and to enable data to be exchanged between two or more components. A system bus may include one of a variety of bus structures including a memory bus or memory controller, a peripheral bus, or a local bus that uses any of a variety of bus architectures. Typical components connected by system bus include processing system 140 and memory. Other typical computer components may include one or more mass storage device interfaces, input interfaces, output interfaces 150, and network interfaces. Components unique to the present invention that may be connected by bus to those just mentioned or to one another include, one or more valve components, one or more pumps, and one or more sensors (e.g. optical, laser, liquid sensors, etc.). The system 100, or its individual components, may be connected to a network 110.
Processing system includes one or more processors, such as a central processor and optionally one or more other processors designed to perform a particular function or task, such as the learning and storing of a pre-determined sprinkler function during a teach mode. It is typically a processing system that executes the instructions provided on computer readable media, such as on memory, a magnetic hard disk, a removable magnetic disk, a magnetic cassette, an optical disk. Processing system may also be operable with a remote computer device through a communication connection 40, which remote computer device may also be a computer readable media such as a remote memory storage device. Memory includes one or more computer readable media that may be configured to include or includes thereon data or instructions for manipulating data, and may be accessed by processing system through system bus. Memory may include, for example, ROM, used to permanently store information, and/or RAM, used to temporarily store information. ROM may include a basic input/output system ("BIOS") having one or more routines that are used to establish communication, such as during startup of computer device. RAM may include one or more program modules, such as one or more operating systems, application programs, and/or program data. One or more mass storage device interfaces may be used to connect one or more mass storage devices to system bus. The mass storage devices may be incorporated into or may be peripheral to computer device and allow computer device to retain large amounts of data. Optionally, one or more of the mass storage devices may be removable from computer device. Examples of mass storage devices include hard disk drives, magnetic disk drives, tape drives and optical disk drives. A mass storage device may read from and/or write to a magnetic hard disk, a removable magnetic disk, a magnetic cassette, an optical disk, or another computer readable medium. Mass storage devices and their corresponding computer readable media provide nonvolatile storage of data and/or executable instructions that may include one or more program modules such as an operating system, one or more application programs, other program modules, or program data. Such executable instructions are examples of program code means for implementing steps for methods disclosed herein. One or more input interfaces may be employed to enable a user to enter data and/or instructions to computer device through one or more corresponding input devices. One or more output interfaces may be employed to connect one or more corresponding output devices to system bus. Examples of output devices include a monitor or display screen and the like.
In another aspect is a method of washing containers comprising placing a container in communication with a delivery conduit and/or nozzle of an apparatus for washing containers, wherein the apparatus for washing containers comprises a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and nozzle, wherein the fluid delivery member is adapted for insertion into the container and wherein the interconnected fluid delivery members form a manifold which is in fluidic communication with a fluid source, and initiating a flow of fluid through the apparatus for a predetermined period of time (e.g. about 10 minutes) or until a pre-determined volume of fluid is passed through the apparatus (e.g. about 50L) or each fluid delivery member (e.g. between about 4L and about 8L). In some embodiments, the method further comprises the step of regulating a fluid flow through the apparatus. In some embodiments, the step of regulating the fluid flow is achieved by controlling one or more valves. In some embodiments, a cleaning fluid, e.g. a decontaminating fluid, is first introduced into the containers, either manually or through use of the disclosed apparatus. Then, the cleaning fluid is washed from the containers by means of the apparatus (or system) and method described herein.
In some embodiments of the method, a single fluid is provided to the apparatus. In other embodiments, multiple different fluids (or the same fluid having a different concentration of one or more components) are introduced into the system, and the different fluids are introduced at different sections of the apparatus or at different times. The skilled artisan will appreciate that, as provided herein, a second concentrated fluid may be introduced at a port different than the inlet valve 30, and the concentrated fluid may be allowed to mix with a first fluid introduced at inlet 30. Of course, the concentration of the mixed fluid may be varied based on the amount of second concentrated fluid introduced or metered into the apparatus. Although the invention herein has been described with reference to particular embodiments, it is to be understood that these embodiments are merely illustrative of the principles and applications of the present invention. It is therefore understood that numerous modifications may be made to the illustrative embodiments and that other arrangements may be devised without departing from the spirit and scope of the present invention as defined by the appended claims. The foregoing written specification is considered to be sufficient to enable one skilled in the art to practice the invention.

Claims

PATENT CLAIMS
An apparatus for washing containers comprising a plurality of interconnected fluid delivery members, each fluid delivery member comprising an elongate delivery conduit and a nozzle, wherein the fluid delivery member is adapted for insertion into a container and wherein said interconnected fluid delivery members form a manifold which is in fluidic communication with an aqueous fluid source.
The apparatus of claim 1, wherein said apparatus comprises between 1 and 12 fluid delivery members.
The apparatus of claim 1 , wherein said apparatus comprises between 3 and 7 fluid delivery members.
The apparatus of any of claims 1 to 3, further comprising at least one support conduit having a fluid inlet, wherein said at least one support conduit is in fluidic communication with said manifold and said fluid source.
The apparatus of claim 4, wherein said support conduit further comprises at least one inlet valve positioned near said fluid inlet to regulate the flow of fluid through said support conduit.
The apparatus of claim 4 or 5, wherein said apparatus comprises two support conduits.
The apparatus of claim 6, wherein a first of said two support conduits is attached to and in fluidic communication with a first end of said manifold and a second of said two support conduits is attached to and in fluidic communication with a second end of said manifold, wherein each of said support conduits are arranged parallel to each other and perpendicular to said manifold.
The apparatus of claim 6 or 7, further comprising at least one cross-member bridging said support conduits.
The apparatus of any of claims 1 to 8, wherein each of said fluid delivery members comprises at least one valve to regulate fluid flow between said interconnected fluid delivery members.
10. The apparatus of claim 9, said at least one valve is electrically actuated.
11. The apparatus of any of claims 1 to 10, wherein said delivery conduit comprises a valve or pressure regulator to regulate fluid flow or pressure to said nozzle. 12. The apparatus of claim 11, wherein said delivery valve is electrically actuated.
13. The apparatus of any of claims 1 to 12, wherein said manifold is comprised of modular fluid delivery members.
14. The apparatus of any of claims 1 to 13, wherein any of the fluid delivery members are comprised of a material selected from the group consisting of synthetic rubbers, phenol formaldehyde resins, nylons, polyvinyl chloride, polystyrene, polyethylene, polypropylene, polyacrylonitrile, polyvinyl butyral, silicone, polyoxymethylene, acrylonitrile butadiene styrene, and any combination thereof. 15. A system for washing containers comprising the apparatus of claim 5 and a timer, wherein said timer controls an operation of said inlet valve.
16. A system for washing containers comprising the apparatus of any of claims 1 to 14, a pump, and a timer, wherein said timer operably controls said pump to regulate fluid flow to said apparatus. 17. A system for washing containers comprising the apparatus of claim 1, one or more valves, and a computer in communication with said one or more valves.
18. The system of claim 17, further comprising a pump, wherein said computer is in communication with said pump.
19. The system of claim 17 or 18, further comprising one or more sensors, wherein said computer is in communication with said one or more sensors.
20. A method of washing containers comprising placing a container in communication with the delivery conduit or nozzle of the apparatus of any of claims 1 to 14, and initiating a flow of fluid through the apparatus for a predetermined period of time or until a pre-determined volume of the fluid passes through the apparatus.
21. The method of washing containers of claim 20, wherein said method further comprises the step of regulating a fluid flow through the apparatus.
22. The method of washing containers of claim 21, wherein said step of regulating said fluid flow is achieved by controlling one or more valves. 23. The method of any of claims 20 to 22, further comprising the step of pre- rinsing said container with a decontamination fluid.
PCT/EP2016/069960 2015-08-27 2016-08-24 Laboratory container washing apparatus and system WO2017032788A1 (en)

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US201562210562P 2015-08-27 2015-08-27
US62/210,562 2015-08-27

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3070104A (en) * 1958-03-26 1962-12-25 R G Wright Company Inc Glassware washer
US3907011A (en) * 1973-10-09 1975-09-23 Ernest R Edmunds Liquid transfer apparatus for use in the washing of containers
EP0577568A1 (en) * 1992-06-30 1994-01-05 OFFICINE AVE S.p.A. A rotary rinsing machine provided with a device for controlling and dispensing substances for the treatment of bottles, vases or the like

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3070104A (en) * 1958-03-26 1962-12-25 R G Wright Company Inc Glassware washer
US3907011A (en) * 1973-10-09 1975-09-23 Ernest R Edmunds Liquid transfer apparatus for use in the washing of containers
EP0577568A1 (en) * 1992-06-30 1994-01-05 OFFICINE AVE S.p.A. A rotary rinsing machine provided with a device for controlling and dispensing substances for the treatment of bottles, vases or the like

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