WO2016190689A3 - Composition for preventing, alleviating or treating muscle diseases or improving muscular function - Google Patents

Composition for preventing, alleviating or treating muscle diseases or improving muscular function Download PDF

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Publication number
WO2016190689A3
WO2016190689A3 PCT/KR2016/005597 KR2016005597W WO2016190689A3 WO 2016190689 A3 WO2016190689 A3 WO 2016190689A3 KR 2016005597 W KR2016005597 W KR 2016005597W WO 2016190689 A3 WO2016190689 A3 WO 2016190689A3
Authority
WO
WIPO (PCT)
Prior art keywords
sargassum
composition
fulvellum
extract
fusiforme
Prior art date
Application number
PCT/KR2016/005597
Other languages
French (fr)
Korean (ko)
Other versions
WO2016190689A2 (en
Inventor
황재관
김창희
김미보
Original Assignee
연세대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 연세대학교 산학협력단 filed Critical 연세대학교 산학협력단
Priority to JP2018514759A priority Critical patent/JP6818018B2/en
Priority to US15/577,098 priority patent/US10646498B2/en
Priority claimed from KR1020160064917A external-priority patent/KR101809156B1/en
Publication of WO2016190689A2 publication Critical patent/WO2016190689A2/en
Publication of WO2016190689A3 publication Critical patent/WO2016190689A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus

Abstract

The present invention relates to a composition for preventing or treating muscle diseases or improving muscular function, containing fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract. According to the present invention, fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, since the composition of the present invention is a natural product, the composition can be safely used without side effects, thereby being usable in medicine, food, cosmetic products, livestock feed, a feed additive and the like.
PCT/KR2016/005597 2015-05-26 2016-05-26 Composition for preventing, alleviating or treating muscle diseases or improving muscular function WO2016190689A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2018514759A JP6818018B2 (en) 2015-05-26 2016-05-26 Composition for prevention, improvement or treatment of muscle diseases or improvement of muscle function
US15/577,098 US10646498B2 (en) 2015-05-26 2016-05-26 Composition for preventing, alleviating or treating muscle diseases or improving muscular function

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2015-0072740 2015-05-26
KR20150072740 2015-05-26
KR10-2016-0064917 2016-05-26
KR1020160064917A KR101809156B1 (en) 2015-05-26 2016-05-26 Composition for prevention, improvement or treatment of muscular disorder or improvement of muscular functions comprising fucosterol

Publications (2)

Publication Number Publication Date
WO2016190689A2 WO2016190689A2 (en) 2016-12-01
WO2016190689A3 true WO2016190689A3 (en) 2017-01-12

Family

ID=57393558

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/005597 WO2016190689A2 (en) 2015-05-26 2016-05-26 Composition for preventing, alleviating or treating muscle diseases or improving muscular function

Country Status (1)

Country Link
WO (1) WO2016190689A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107298696A (en) * 2017-06-22 2017-10-27 舟山富晟食品科技有限公司 The extracting method of sargassum fusifome activated protein
WO2019022263A1 (en) * 2017-07-24 2019-01-31 강릉원주대학교 산학협력단 Composition for treating atopic dermatitis

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000063617A (en) * 2000-07-26 2000-11-06 왕종근 Seaweed extract product having immuno-enhancement activity and methods of producing and utilizing the same
KR20050006533A (en) * 2003-07-09 2005-01-17 이재화 Method obtaining extracts having anti-cancer effect and immune enhancing activity from marine algae
JP2009191008A (en) * 2008-02-14 2009-08-27 South Product:Kk Method for extracting functional component derived from brown algae
KR20140060106A (en) * 2012-11-09 2014-05-19 한국생명공학연구원 Neuroprotective composition comprising extracts or fractions of seaweed as an active ingredient
KR20140081339A (en) * 2012-12-21 2014-07-01 부경대학교 산학협력단 Pharmaceutical composition for prevention or treatment of neurodegenerative disease comprising fucosterol
KR20140131100A (en) * 2013-05-03 2014-11-12 경희대학교 산학협력단 Composition for skin beauty food, drug and cosmetic use comprising an extract of Fucosterol

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000063617A (en) * 2000-07-26 2000-11-06 왕종근 Seaweed extract product having immuno-enhancement activity and methods of producing and utilizing the same
KR20050006533A (en) * 2003-07-09 2005-01-17 이재화 Method obtaining extracts having anti-cancer effect and immune enhancing activity from marine algae
JP2009191008A (en) * 2008-02-14 2009-08-27 South Product:Kk Method for extracting functional component derived from brown algae
KR20140060106A (en) * 2012-11-09 2014-05-19 한국생명공학연구원 Neuroprotective composition comprising extracts or fractions of seaweed as an active ingredient
KR20140081339A (en) * 2012-12-21 2014-07-01 부경대학교 산학협력단 Pharmaceutical composition for prevention or treatment of neurodegenerative disease comprising fucosterol
KR20140131100A (en) * 2013-05-03 2014-11-12 경희대학교 산학협력단 Composition for skin beauty food, drug and cosmetic use comprising an extract of Fucosterol

Also Published As

Publication number Publication date
WO2016190689A2 (en) 2016-12-01

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