WO2016159583A3 - Composition for innate immunity enhancement and antiviral activity containing hovenia dulcis extract as active ingredient - Google Patents

Composition for innate immunity enhancement and antiviral activity containing hovenia dulcis extract as active ingredient Download PDF

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Publication number
WO2016159583A3
WO2016159583A3 PCT/KR2016/003043 KR2016003043W WO2016159583A3 WO 2016159583 A3 WO2016159583 A3 WO 2016159583A3 KR 2016003043 W KR2016003043 W KR 2016003043W WO 2016159583 A3 WO2016159583 A3 WO 2016159583A3
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WO
WIPO (PCT)
Prior art keywords
innate immunity
antiviral activity
immunity enhancement
enhancement
hovenia dulcis
Prior art date
Application number
PCT/KR2016/003043
Other languages
French (fr)
Korean (ko)
Other versions
WO2016159583A2 (en
Inventor
마진열
조원경
이종수
Original Assignee
한국 한의학 연구원
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 한국 한의학 연구원 filed Critical 한국 한의학 연구원
Publication of WO2016159583A2 publication Critical patent/WO2016159583A2/en
Publication of WO2016159583A3 publication Critical patent/WO2016159583A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to a pharmaceutical composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a health functional food for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a feed composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, and a method for innate immunity enhancement and antiviral activity enhancement in an animal, the method comprising administering a Hovenia dulcis extract to an animal excluding humans, in need of innate immunity enhancement. The Hovenia dulcis-containing composition for innate immunity enhancement and antiviral activity according to the present invention exhibits antiviral activity and innate immunity enhancement efficacy, and thus can be applied for prevention and treatment of bacterial and viral infectious diseases, and can be widely used for a medicine or a health functional food for immunity enhancement and regulation in immunodeficient or immunosuppressed patients and for a feed for innate immunity enhancement and antiviral activity, for the purpose of anti-disease enhancement of animals. Furthermore, the composition for innate immunity enhancement and antiviral activity according to the present invention scarcely causes toxicity or side effects, and thus can be safely used even in the long-term use for prophylactic purposes.
PCT/KR2016/003043 2015-03-27 2016-03-25 Composition for innate immunity enhancement and antiviral activity containing hovenia dulcis extract as active ingredient WO2016159583A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2015-0042930 2015-03-27
KR1020150042930A KR101762608B1 (en) 2015-03-27 2015-03-27 Composition for enhancing innate immunity and antivirus comprising Hoveniae Semen Cum Fructus extract as effective component

Publications (2)

Publication Number Publication Date
WO2016159583A2 WO2016159583A2 (en) 2016-10-06
WO2016159583A3 true WO2016159583A3 (en) 2016-12-08

Family

ID=57007036

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/003043 WO2016159583A2 (en) 2015-03-27 2016-03-25 Composition for innate immunity enhancement and antiviral activity containing hovenia dulcis extract as active ingredient

Country Status (2)

Country Link
KR (1) KR101762608B1 (en)
WO (1) WO2016159583A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022065971A2 (en) * 2020-09-28 2022-03-31 한국한의학연구원 Composition for prevention or treatment of coronavirus infection, comprising hovenia dulcis thunb extract
KR102570597B1 (en) * 2021-06-28 2023-08-29 한국한의학연구원 Nature extract of anti influenza virus and composition containing the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060099225A (en) * 2005-03-11 2006-09-19 주식회사 엘지생활건강 Composition containing hovenia dulcis fruit extract having anti-inflammatory effect and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060099225A (en) * 2005-03-11 2006-09-19 주식회사 엘지생활건강 Composition containing hovenia dulcis fruit extract having anti-inflammatory effect and use thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FANG, H. -L. ET AL.: "Treatment of Chronic Liver Injuries in Mice by Oral Administration of Ethanolic Extract of the Fruit of Hovenia Dulcis.", THE AMERICAN JOURNAL OF CHINESE MEDICINE, vol. 35, no. 4, 2007, pages 693 - 703 *
KIM, H. -L. ET AL.: "The AMPK Pathway Mediates an Anti-adipogenic Effect of Fruits of Hovenia Dulcis Thunb.", FOOD & FUNCTION, vol. 5, 2014, pages 2961 - 2968, XP055332353 *
LEE, J. J. ET AL.: "Liver Fibrosis Protective Effect of Hovenia Dulcis Fruit.", CURRENT TOPICS IN NUTRACEUTICALS RESEARCH, vol. 12, no. 1/2, 2014, pages 43 - 50, XP055332354 *
WANG, M. ET AL.: "Preparation, Preliminary Characterization and Immunostimulatory Activity of Polysaccharide Fractions from the Peduncles of Hovenia Dulcis.", FOOD CHEMISTRY, vol. 138, 2013, pages 41 - 47, XP055332350 *

Also Published As

Publication number Publication date
KR20160115374A (en) 2016-10-06
KR101762608B1 (en) 2017-08-04
WO2016159583A2 (en) 2016-10-06

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