WO2016135119A1 - Method for the diagnosis of endometrial carcinoma - Google Patents

Method for the diagnosis of endometrial carcinoma Download PDF

Info

Publication number
WO2016135119A1
WO2016135119A1 PCT/EP2016/053726 EP2016053726W WO2016135119A1 WO 2016135119 A1 WO2016135119 A1 WO 2016135119A1 EP 2016053726 W EP2016053726 W EP 2016053726W WO 2016135119 A1 WO2016135119 A1 WO 2016135119A1
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
model
endometrial carcinoma
classification
metabolites
Prior art date
Application number
PCT/EP2016/053726
Other languages
English (en)
French (fr)
Inventor
Jacopo TROISI
Giovanni SCALA
Pietro CAMPIGLIA
Fulvio ZULLO
Maurizio Guida
Original Assignee
Hosmotic Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITUB2015A000390A priority Critical patent/ITUB20150390A1/it
Priority to IT102015000007151 priority
Application filed by Hosmotic Srl filed Critical Hosmotic Srl
Priority claimed from ES16709979T external-priority patent/ES2711814T3/es
Publication of WO2016135119A1 publication Critical patent/WO2016135119A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57442Specifically defined cancers of the uterus and endometrial
PCT/EP2016/053726 2015-02-27 2016-02-23 Method for the diagnosis of endometrial carcinoma WO2016135119A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITUB2015A000390A ITUB20150390A1 (it) 2015-02-27 2015-02-27 Metodo per la diagnosi di carcinoma endometriale
IT102015000007151 2015-02-27

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES16709979T ES2711814T3 (es) 2015-02-27 2016-02-23 Método para el diagnóstico de carcinoma endometrial
EP16709979.5A EP3262416B1 (en) 2015-02-27 2016-02-23 Method for the diagnosis of endometrial carcinoma
JP2017563386A JP6731957B2 (ja) 2015-02-27 2016-02-23 子宮内膜癌の診断方法
US15/552,342 US20180038867A1 (en) 2015-02-27 2016-02-23 Method for the diagnosis of endometrial carcinoma

Publications (1)

Publication Number Publication Date
WO2016135119A1 true WO2016135119A1 (en) 2016-09-01

Family

ID=53284421

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2016/053726 WO2016135119A1 (en) 2015-02-27 2016-02-23 Method for the diagnosis of endometrial carcinoma

Country Status (2)

Country Link
IT (1) ITUB20150390A1 (da)
WO (1) WO2016135119A1 (da)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007057309A (ja) * 2005-08-23 2007-03-08 Yoshikimi Kikuchi 子宮体癌の検出方法
JP2007147459A (ja) * 2005-11-28 2007-06-14 Kazusa Dna Kenkyusho 情報処理装置、プログラム、及びコンピュータ読み取り可能な記録媒体
WO2011161186A1 (en) * 2010-06-23 2011-12-29 Biocrates Life Sciences Ag Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007057309A (ja) * 2005-08-23 2007-03-08 Yoshikimi Kikuchi 子宮体癌の検出方法
JP2007147459A (ja) * 2005-11-28 2007-06-14 Kazusa Dna Kenkyusho 情報処理装置、プログラム、及びコンピュータ読み取り可能な記録媒体
WO2011161186A1 (en) * 2010-06-23 2011-12-29 Biocrates Life Sciences Ag Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CAO Q JACKIE ET AL: "Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium", INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, vol. 23, no. 4, October 2004 (2004-10-01), pages 321 - 329, XP008177794, ISSN: 0277-1691 *
DENKERT C. ET AL.: "Metabolite profiling of human colon carcinoma - deregulation of TCA cycle and amino acid turnover", MOL. CANCER, vol. 7, 2008, pages 1 - 15
FAN L. ET AL.: "Identification of metabolic biomarkers to diagnose epithelial ovarian cancer using a UPLC/Q TOF/MS platform", ACTA ONCOLOGICA, vol. 51, 2012, pages 473 - 479, XP055369606, DOI: doi:10.3109/0284186X.2011.648338
KADDURAH-DAOUK R.: "Metabolic profiling of patients with schizophrenia", PLOS MED, vol. 8, 2006, pages E363
KARKKAINEN J ET AL: "Comparison of mass spectrometry and radioimmunoassay to measure medroxyprogesterone acetate in patients with endometrial cancer", EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY, PERGAMON PRESS LTD, vol. 26, no. 9, 1 January 1990 (1990-01-01), pages 975 - 977, XP026199897, ISSN: 0277-5379, [retrieved on 19900101], DOI: 10.1016/0277-5379(90)90624-3 *
MULLER GL ET AL.: "Allelotype mapping of unstable microsatellites establishes direct lineage continuity between endometrial precancers and cancers", CANCERS RES, vol. 56, 1996, pages 4483
PETER PODOLEC ET AL: "Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES & APPLICATIONS., vol. 967, 1 September 2014 (2014-09-01), NL, pages 134 - 138, XP055220248, ISSN: 1570-0232, DOI: 10.1016/j.jchromb.2014.07.023 *
SUBRAMANIAN A. ET AL.: "Proton MR/CSF analysis and a new software as predictors for the differentiation of meningitis in children", NMR BIOMED, vol. 18, 2005, pages 213 - 225
VAPNIK, V.: "Estimation of Dependences Based on Empirical Data", 1982, SPRINGER VERLAG

Also Published As

Publication number Publication date
ITUB20150390A1 (it) 2016-08-27

Similar Documents

Publication Publication Date Title
de Noo et al. Detection of colorectal cancer using MALDI-TOF serum protein profiling
EP2279417B1 (en) Metabolic biomarkers for ovarian cancer and methods of use thereof
Fan et al. Identification of metabolic biomarkers to diagnose epithelial ovarian cancer using a UPLC/QTOF/MS platform
Pagni et al. Proteomics in thyroid cytopathology: Relevance of MALDI‐imaging in distinguishing malignant from benign lesions
WO2013016700A1 (en) Methods for generating predictive models for epithelial ovarian cancer and methods for identifying eoc
Mascini et al. Tumor classification with MALDI-MSI data of tissue microarrays: A case study
WO2008092280A1 (en) Methods for the diagnosis of ovarian cancer health states and risk of ovarian cancer health states
JP2013522652A (ja) 代謝物プロファイリングを用いた再発乳癌の早期検出
US20180180619A1 (en) Means and Methods for Diagnosing Pancreatic Cancer in a Subject Based on a Biomarker Panel
Wanichthanarak et al. Accounting for biological variation with linear mixed-effects modelling improves the quality of clinical metabolomics data
Zhou et al. Metabonomic classification and detection of small molecule biomarkers of malignant pleural effusions
EP3262416B1 (en) Method for the diagnosis of endometrial carcinoma
Huang et al. Liquid chromatography–mass spectrometry based serum peptidomic approach for renal clear cell carcinoma diagnosis
Han et al. Support vector machines coupled with proteomics approaches for detecting biomarkers predicting chemotherapy resistance in small cell lung cancer
Yang et al. Proteomic profiling of invasive ductal carcinoma (IDC) using magnetic beads‐based serum fractionation and MALDI‐TOF MS
US11462305B2 (en) Biomarkers for detecting colorectal cancer or adenoma and methods thereof
US20140162903A1 (en) Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment
Tong et al. A simpler method of preprocessing MALDI-TOF MS data for differential biomarker analysis: stem cell and melanoma cancer studies
Lumbreras et al. Sources of error and its control in studies on the diagnostic accuracy of “‐omics” technologies
WO2016135119A1 (en) Method for the diagnosis of endometrial carcinoma
WO2018136085A1 (en) Methods and compositions for providing an early stage ovarian cancer assessment with metabolites
Pyatnitskiy et al. Identification of differential signs of squamous cell lung carcinoma by means of the mass spectrometry profiling of blood plasma
US20170138930A1 (en) Non-invasive diagnostic method for the early detection of fetal malformations
KR20130079988A (ko) 위암 진단 장치
CN112255333B (zh) 卵巢肿瘤尿液代谢标志物及其应用

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16709979

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 15552342

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2017563386

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2016709979

Country of ref document: EP