WO2016128730A1 - Contenant - Google Patents

Contenant Download PDF

Info

Publication number
WO2016128730A1
WO2016128730A1 PCT/GB2016/050300 GB2016050300W WO2016128730A1 WO 2016128730 A1 WO2016128730 A1 WO 2016128730A1 GB 2016050300 W GB2016050300 W GB 2016050300W WO 2016128730 A1 WO2016128730 A1 WO 2016128730A1
Authority
WO
WIPO (PCT)
Prior art keywords
blank
perforations
blister pack
tab
cut
Prior art date
Application number
PCT/GB2016/050300
Other languages
English (en)
Inventor
David Appleby
Jimi Simpson
Original Assignee
Marsoftware Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marsoftware Limited filed Critical Marsoftware Limited
Publication of WO2016128730A1 publication Critical patent/WO2016128730A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/30—Compliance analysis for taking medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/30—Printed labels

Definitions

  • the present invention relates to a container suitable for holding objects and/or liquids, for example but not limited, to a pill container.
  • pill means a small object including a medicinal substance, the object intended to be taken orally by a patient. Included in definition of the term “pill” is vitamins, minerals and/or any other medicament or substance to be ingested by an individual. It includes tablets formed by moulding of the substance alone or with a carrier and capsules having powdered substance within a soluble shell, tablets and capsules being the two most common form of pill. Although exemplified herein is a pill container, it will be appreciated that the container need not contain or be designed to contain a pill(s). Instead, it will be appreciated that the container described herein may be designed so as to be suitable to contain any object and/or liquid.
  • MAR data medication administration records
  • the compartments are generally sealed with an impermeable film adhered to lands around and between the compartments in the tray, the latter is conveniently a vacuum/pressure formed moulding.
  • a card identifying the intended day and part of the day at which the pills should be taken can be added to the sealed tray. Indeed, this card can be added before the tray is populated.
  • the card can incorporate the compartment sealing film and adhesive for adhering to both sides of the lands between the compartments.
  • a card may be provided having double the number of apertures as compartments in the tray.
  • the compartments of the tray extend through one array of apertures in one piece or section of the card.
  • a fold in this piece of card is provided to another piece or section of the card, having another array of apertures which are brought into register with the compartments, on folding of the card.
  • a third piece of the card may optionally be folded over the compartments.
  • the entire populated assembly is referred herein as a pill box; however, it will be appreciated that this assembly need not contain pills.
  • the tray is separate from the card, in some exemplary embodiments, the tray may be integrated therewith.
  • the card comprises three sections configured so as to be folded in respect of each other, the card need not comprise three sections. Indeed, the card may comprise any number of sections. In other embodiments, the sections referred to herein may be distinct and preferably may be configured such that they are alignable and/or attachable.
  • Non-adherence occurs when patients do not take their medicine appropriately or at all. Non-adherence is a serious problem worldwide as it can result in serious deterioration of the medical condition and has avoidable and costly complications.
  • Smart pack technologies are available that enable adherence monitoring. It has been proposed to provide electric circuit tracks on the compartment closure and sealing film, together with a connection tail. The arrangement was to include a respective circuit for each compartment and intended to allow interrogation of the integrity of each compartment's circuit, whereby opening of the compartment and implied taking of the pills by the patient could be recorded.
  • each aperture having an openable tab across the aperture, the tab being tearable to allow pill (s) to pass through the aperture,
  • MARS pill pack and tag means:
  • each aperture having an openable tab across the aperture, the tab being tearable to allow pill(s) to pass through the aperture,
  • a tag having complementary contacts connected to the card contacts, the tag being for recording circuit opening on tab opening for taking of a pill by a patient.
  • a card for a MARS pill pack and tag
  • the card having:
  • openable tabs wherein the openable tabs are initially connected to the card at perforations generally arrayed in one direction and at least some neighbouring perforations having ends spaced transversally of the direction of array.
  • the perforations are provided at the top and bottom portions of the openable tab.
  • the openable tab may be formed with cut-outs either side of the tab.
  • the perforations maybe provided along a region having a central axis or direction.
  • a T-shaped perforation and two linear perforations are provided.
  • the linear perforations may be substantially parallel to the central axis, extend to the cut-outs, and are out of alignment with the head of the T perforation.
  • the length of the head may vary depending on the extent of the overlap with the linear perforations that is required.
  • the T may be of a conventional shape with the stem being longer than the head or the length ratio between the stem and head maybe reversed.
  • the linear perforations may further extend at an angle or curve towards the stem of the T perforation.
  • a V-shaped perforation as opposed to a T-shape perforation, may be provided.
  • the perforations may extend oblique to the axis and the length, pitch and orientation of these perforations may vary.
  • the perforations may be arranged in a manner such that they are offset from the central axis.
  • the tabs can be rendered tearable by means of perforated portion(s) at adjacent parts of the card.
  • a common feature of all the perforations may be that the conductive tab-crossing line section for the aperture crosses the tearable, partially cut or perforated portion whereby on tearing the line's continuity is broken.
  • the conductive line layer can be applied directly to the lands of the tray to close the compartments of the tray.
  • a separate tray compartment closure layer can be provided, to which the conductive line layer is adhered on closure of the pack.
  • the conductive line layer can be of paper, that is a thin material produced by pressing together moist fibres, typically cellulose pulp derived from wood, rags or grasses, and drying them into flexible sheets.
  • the conductive line layer can be a film of homogeneous polymeric material.
  • the conductive line layer could be a metallic foil or a metalised film, with insulation between the metal and the conductive lines.
  • the conductive lines could be produced by sophisticated means such as deposition and partial etching of metal. However, they are preferably provided by high speed flexographic printing and drying of conductive inks.
  • the card (for a MARS pill pack and tag), the card having:
  • openable tabs wherein the openable tabs are:
  • a full cut line in this aspect/embodiment, can be foil depth through the card, but intermittent as in a perforation.
  • a partial cut line it can be of partial depth, either continuous or intermittent.
  • the partial or full cut line is generally substantially parallel with the array direction and has ends which curve to or close to each cutout to form an elongated s-shape line between adjacent tabs. It may be envisaged that the ends do not curve towards the cut-outs and only a vertical line parallel to the array direction is provided.
  • the perforations are generally substantially arrayed in one direction and at least some neighbouring perforations have ends spaced substantially transversally of the direction of array.
  • Figure 1 is an inside surface view of a card for a pill pack in accordance with one embodiment
  • Figure 2 is a top view of the card of Figure 1 ;
  • Figure 3 is an outside surface view of the card of Figure 1 ;
  • Figure 4 is a perspective view of a pill tray for the card of Figure 1 ;
  • Figure 5 is a conductive lines and perforations layout on the outside surface of a central piece of the card of Figure 1 ;
  • Figure 6 is a scrap view of the card of Figure 5 showing the direction of the array
  • Figure 7 is the tearable tab as shown in Figure 5 before the conductive lines have been printed;
  • Figures 8 - 16 are alternative tearable tabs for the card of Figure 5 (before the conductive lines have been printed);
  • Figure 1 7 is an inside surface view of a card for a pill pack in accordance with a second aspect of the invention.
  • Figure 1 8 is a view of the card with pull tab cuts and circuit overlaid of a central piece of the card of Figure 1 , according to an additional or alternative aspect or embodiment.
  • a card 1 for example suitable for a pill pack and/or other container, has three pieces 2,3,4 connected by a single fold 5 between pieces 2 and3 and a double fold 6,7 between pieces 3 and 4.
  • the inner face 8 of card in this embodiment is preferably coated with adhesive covered with a release paper 9.
  • the card comprises three pieces or sections, it will be appreciated that any number of sections (including the singular) can be provided.
  • the pieces 2,3,4 are folded, it will be appreciated they need not be and in fact any other suitable arrangement can be provided; for example, the pieces can be separate but adapted so as to align, for example so as each lay substantially flush in respect of each other.
  • the card piece 2 in this embodiment has an array of 28 apertures 1 0 for the 28 compartments 1 1 of a vacuum formed (or other known manufacture method for producing a tray) tray 12. Its adhesive adheres to the underside of lands 13 between and around the outer edges of the compartments 1 1 .
  • the release paper 9 is peeled from the piece 2 and, the tray 12 is adhered in place and populated with pills (not shown).
  • the card may by provided with any number of apertures (including the singular), preferably corresponding to compartments provided on a respective tray. Further, it will be appreciated that the tray and/or compartments may be integrated with the card.
  • a closure film 15 is preferably adhered across a complementary array of 28 apertures 16 in the card piece 3 and optionally has adhesive applied to its release paper side.
  • the card piece 3 is folded onto the tray, with the film coming into adherence with the lands of the tray.
  • the pills are contained.
  • the card piece 3 may be provided with any number of apertures (including the singular), preferably corresponding to apertures of card piece 2.
  • the closure film 1 5 may be integral with or separate from card piece 3.
  • the outer face 18 of the card in this embodiment has printing 19, typically high-speed flexo- graphic printing, including an indication of the time of day and days of intended opening of each compartment and taking of the pills. It will be appreciated that the outer face need not comprise printing. In alternative embodiments, a sticker or other means may be provided to provide contextual information regarding the container.
  • the apertures 16 in the second, central card piece 3 are preferably initially not complete. They are crossed by respective tabs 21 . These are cut completely from the Y-axis lands 22 between the apertures at their sides, leaving broad V shaped cut-outs 23. However, they remain connected at their top and bottom portions 24 to the X-axis lands 25. Perforations 26 are provided for ease of tearing of the tabs 21 from the card piece. Conveniently, this may be done by supporting the card from below at the lands and pushing the relevant compartment down, rupturing the film sheet at the compartment and tearing the tab, with the pills being ejected into a hand below; for example, by using the thumb and a finger in a pinching and pulling motion.
  • the perforations 26 are generally arrayed substantially in one direction (line X-X showing the direction of array 28) with at least some neighbouring perforations having ends spaced substantially transversally of the direction of array.
  • the perforations 26 are provided at one or both of the top and bottom portions 24 substantially to the lands 25 which extend substantially parallel to this x axis. They are provided along a region having a central axis 20 or direction 28 (line X-X showing the array direction 28).
  • a T-shaped perforation 44 and two perforations 45 may be provided.
  • the perforations 45 are preferably out of alignment with the heads 55 and extend substantially to the cut-outs 23. Providing these perforations and alignment advantageously assists in effectively distributing stresses induced by the press manufacture when pulled along under tension and/or around a large number of circular rollers that flex the card in different directions.
  • the two perforations 45 may be provided to be substantially parallel to the axis 28.
  • the perforation ends 48 distal from the cut outs 23, may curve or angle towards the stem of the T.
  • the head of the T can be substantially longer, in this example three times longer, than the stem. Indeed, as in Figure 9 the stem can be as short as sixth of the length of the head.
  • Figure 8 shows an intermediate ratio of stem to head length.
  • Figures 1 0 and 1 1 show inverse ratios with the stem being longer than the head (as in a more conventional T).
  • the head of the T may be of a length to overlap the perforations 45 or as shown in Figures 1 ,9, 10 and 1 1 1 the head of the T may be of a length to not overlap the perforations 45. It will be appreciated that the length of the head will determine the extent of overlap with the perforations 45.
  • the T-shaped perforation may be replaced with a V-shaped perforation 50.
  • the perforations 45 are shown to curve toward the bottom of the V and the head (or top) of the V is in alignment with the perforations.
  • the perforations 45 may be of a form as described above for Figures 7 to 1 1 and that the head (or top) of the V may be out of alignment with the perforations 45.
  • the V arms may be of a length so as to overlap with the perforations 45. It will be appreciated that the length and angle of the arms will determine the extent of overlap with the perforations 45.
  • the perforation may be U- shaped and/or the T-/V- shaped perforation may comprise curved sections.
  • perforations 52 and 53 may be provided. Perforations 52 may extend substantially oblique to the axis 28 and perforations 53 are provided substantially parallel to the axis 28 and extend to the cut-outs 23. As shown in Figure 15 the perforations 52,53 are of a length, pitch and orientation such as not to overlap. The pitch being the distance between each perforation. Indeed, as shown in Figures 13 to 15, it will be appreciated that whether the perforations overlap is a function of their length, pitch and orientations with regard to the direction.
  • the tabs 21 may comprise only one broad V-shaped cut-out 57 with perforations 54 provided along the axis 28 and having a perforation extending to the cut-out 57.
  • the perforations 54 are formed of two arms whereby one arm 58 is provided parallel to the axis 28 and one arm 59 extends from the parallel arm at a substantially oblique angle to the axis.
  • the middle sheet piece 3 has a large rectangular aperture 31 with an up-standing wide tongue 32.
  • the first sheet piece 2 preferably has a corresponding aperture 43.
  • the sheet piece 4 in this embodiment has no such aperture.
  • Printed onto the outer face 18, optionally by high-speed flexo-graphic printing may be a series of conductive lines 33 with a linear series of contacts 34 extending onto the tongue 32.
  • the conductive lines may be over printed with background colour 35, typically white, onto which the graphic printing 19 is printed.
  • the layout of the conductive lines may be arranged such that a common contact 36 leads to common lines 37, extending via branches 38 to one or other of the perforated top and bottom portions 24 of each tab. At these portions and indeed the opposite perforated portions the conductive printing is extended to the width of the portions whereby cutting of the perforations does not interrupt electrical conductivity.
  • a tab-crossing line section 39 is provided on each tab, between the wide portions at the perforations.
  • the line has wide ends 40 on either, but more preferably both, end of tab-crossing line section 39 to increase conduction prior to tearing of the tab's perforations.
  • Unique lines 41 for each tab extend away from the latter to unique ones of the contacts.
  • the arrangement is that from each tab's unique contact, there is a continuous circuit to the common contact across the tab. Breaking of the circuit, as in breaking of the tab to take the contents of the container, for example pills in its compartment, breaks the circuit. This can be detected by a tag, for example the "MARS tag", connected to the contacts. It will be appreciated that the tag may be integral with or separate from the card.
  • the card may be made using the following exemplary steps:
  • the conductive lines are preferably over printed with background colour, typically white, onto which further optional graphic printing 19 may be provided.
  • the outer face 18 of the card may have printing, optionally by high-speed flexo-graphic printing, including an indication of the time of day and days of intended opening of each compartment and taking of the pills;
  • the card may be punched, with the punchings 10 and/or 16, the perforations 26 and/or the apertures 31 ;
  • Adhesive may be printed and/or provided by other means on the side shown in
  • a compartment closure foil (not shown) may be applied to the middle piece of card in the region thereof, to cover substantially each of the tabs of the array such that it is aligned with the compartments of the tray, i.e. with the punchings 10, so as to provide a moisture proof seal of the tray, which is particularly preferable when the forming a pill box;
  • Adhesive may be screen-printed and/or provided by other means on to card piece 2 and the compartment closure foil (not shown) for adhering to opposite sides of the lands in the tray between the compartments;
  • a release paper 9 may be applied over the adhesive applied in step 3;
  • the card is cut to size, including punching the conductive line paper in register with the aperture 31 and forming the fold lines 5, 6 and/or 7.
  • the card may be made by any number of the above steps in combination with other alternative known steps. It will also be appreciated that the order of the steps indicated above is exemplary and therefore should not be construed to be limiting.
  • the conductive lines, with a linear series of contacts extending onto the tongue can be printed on the inner face 8 of card 1 (not shown).
  • Figure 6 also shows that the combination of circuit and cut provides an advantageous design tolerance for misalignment typically experienced during manufacture. Not wishing to be bound by theory (and subject to the overall specifications of the card), it is believed that typically a tolerance of around +/-1 mm is achievable with this design.
  • the card have partially or fully cut lines 129 between adjacent tabs 128 whereby each line is formed of a partial or full depth cut parallel to the array direction (i.e. formed in the X- axis lands 125) with one end of the line 130 curving to one cut-out 127 and the other end of the line 131 curving to the other cut-out 127 of the adjacent tab 128 to form an elongated S-shape line.
  • a full cut line it can be full depth through the card, but intermittent as in a perforation.
  • a partially cut line is provided, it can be of partial depth, either continuous or intermittent.
  • the ends do not curve towards the cut-outs and only a vertical line parallel to the array direction is provided (linear cut not shown).
  • the proposed lines provide a fracture tendency if a pull-tab does not pull away correctly.
  • a further compartment closing layer may be incorporated between the tray and the conductive line paper.
  • the conductive line paper could be applied to the other side of the card piece 3, with the conductive lines over printed with graphic printing.
  • the invention is not limited to screen printing of the conductive ink lines. Other forms of printing or indeed other means of applying the lines are possible.
  • a blister pack comprised of a substantially planar substrate provided with a plurality of at least partially closed compartments, each of the at least partially closed compartments comprising an openable tab formed with a conductive element and perforations, wherein each tab is defined at least in part by perforated regions that are, in use, rupturable to open the tab to access the compartment;
  • each conductive line being connectable to a detection is circuit and is arranged to break responsive to the tab being opened, wherein optionally each conductive line can be provided on either side and/or both sides of the planar substrate and/or on (inner) laminates provided thereon.
  • first and second substantially opposed perforated regions defining portions of the periphery of an openable tab are each defined by a plurality of discontinuous perforations.
  • a perforated region is defined by: a. a first substantially linear perforation extending from a first cut out in the direction of the opposed cut out
  • T-shaped linear perforation is arranged such that it's head is arranged outwardly of the tab and its stem is arranged inwardly of the tab.
  • one or more of said perforated regions is formed of a plurality of perforated lines extending in the direction between the cut outs, and wherein at least a portion of two or more individual perforated lines making up the extent of the plurality of perforated lines is angled obliquely with respect to the direction of a line between the cut outs.
  • the blister pack of claim 12 wherein a portion of the conductive line at least partially surrounds a discontinuous perforation making up the perforated region.
  • the discontinuous perforation surrounded by the portion of the conductive line is V-shaped or T-shaped.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)

Abstract

Selon certains modes de réalisation, l'invention concerne une ébauche destinée à être utilisée pour la fabrication d'un emballage-coque, l'ébauche comprenant des perforations disposées en un motif permettant que les perforations répartissent efficacement les contraintes lorsque l'ébauche est maintenue sous tension par des rouleaux et/ou soumise à une flexion. L'invention concerne également un procédé de fabrication d'un emballage-coque comprenant l'ébauche selon l'invention, et un emballage-coque comprenant l'ébauche selon l'invention et/ou fabriqué au moyen du procédé selon l'invention.
PCT/GB2016/050300 2015-02-09 2016-02-09 Contenant WO2016128730A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1502065.4 2015-02-09
GBGB1502065.4A GB201502065D0 (en) 2015-02-09 2015-02-09 Pill container

Publications (1)

Publication Number Publication Date
WO2016128730A1 true WO2016128730A1 (fr) 2016-08-18

Family

ID=52746304

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2016/050300 WO2016128730A1 (fr) 2015-02-09 2016-02-09 Contenant

Country Status (2)

Country Link
GB (1) GB201502065D0 (fr)
WO (1) WO2016128730A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023135418A1 (fr) 2022-01-13 2023-07-20 Yourmedpack Limited Contenant et ses utilisations

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759371A (en) * 1972-07-12 1973-09-18 R Marks Containers for small articles such as pills
US20040175527A1 (en) * 2003-03-05 2004-09-09 3M Innovative Properties Company Cloth-like polymeric film with directional tear
US20050284789A1 (en) * 2004-06-29 2005-12-29 Carespodi Dennis L Laser-scored push-through blister backing and methods of making same
US20090145800A1 (en) * 2006-09-26 2009-06-11 Cadbury Adams Usa Llc Rupturable substrate
WO2014106735A1 (fr) * 2013-01-03 2014-07-10 Marsoftware Limited Boîte pour pilules

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759371A (en) * 1972-07-12 1973-09-18 R Marks Containers for small articles such as pills
US20040175527A1 (en) * 2003-03-05 2004-09-09 3M Innovative Properties Company Cloth-like polymeric film with directional tear
US20050284789A1 (en) * 2004-06-29 2005-12-29 Carespodi Dennis L Laser-scored push-through blister backing and methods of making same
US20090145800A1 (en) * 2006-09-26 2009-06-11 Cadbury Adams Usa Llc Rupturable substrate
WO2014106735A1 (fr) * 2013-01-03 2014-07-10 Marsoftware Limited Boîte pour pilules

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023135418A1 (fr) 2022-01-13 2023-07-20 Yourmedpack Limited Contenant et ses utilisations

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