WO2016028019A1

WO2016028019A1 - Photodynamic diagnosis apparatus

Info

Publication number: WO2016028019A1
Application number: PCT/KR2015/008301
Authority: WO
Inventors: 송원국; 신민선; 권기철
Original assignee: 주식회사 엠지비엔도스코피
Priority date: 2014-08-19
Filing date: 2015-08-07
Publication date: 2016-02-25
Also published as: KR20160022109A; KR101651271B1

Abstract

A photodynamic diagnosis apparatus according to an embodiment of the present invention comprises: a plurality of light sources which irradiate a plurality of lights having wavelengths different from each other; an objective lens which is disposed to face an object; a zoom lens into which light reflected from the object and passing through the objective lens enters; a video member which creates a different image of the object for each wavelength by photographing the light exited from the zoom lens, and outputs the created image for each wavelength by separating the created image for each wavelength into a plurality of channels; an ocular lens which is configured to enable observation of the image of the object with the naked eye; and a plurality of display devices which display the image for each wavelength outputted for each channel.

Description

Photodynamic diagnostic instrument

Embodiments of the present invention relate to an optical system structure of a surgical microscope, and more particularly to a multi-fluorescence photodynamic diagnostic device combined with a surgical microscope.

In general, the eye is an organ that detects the intensity and wavelength of light, and detects the intensity of the light, finds the direction of the light, and recognizes the image of the object.

These eyes are located in the left and right pair of orbits in front of the skull, respectively, and are protected by the upper and lower eyelids, and the eyeballs are connected to the optic nerve in the rear, and the eye wall is made of three layers, and the outer layer is the cornea and the cornea. The sclera is usually called black sclera.

The above-described eye is undergoing surgery for diseases such as cataract, dry eye, and glaucoma due to changes in modern environment, LASIK surgery, LASEK surgery, excimer laser surgery, ICL surgery, etc. Surgical microscopes are used a lot.

The surgical microscope generally includes a light source for irradiating light by a power source, an optical cable for connecting the light of the light source to the affected part of the patient, an objective lens for enlarging the eyeball of the patient, and the enlarged It consists of an eyepiece for visual confirmation of the eye.

The surgical microscope is a light irradiated from the light source shines brightly on the affected part of the patient along the optical cable, and the eye is greatly enlarged by the objective lens to observe and operate through the eyepiece.

Related prior arts are registered in Korean Patent Publication No. 10-0499243 (name of the invention: a surgical microscope using infrared rays, registered date: June 24, 2005).

According to an embodiment of the present invention, the image for each wavelength separated by the beam splitter is converted into image data through each camera and displayed on each display device, thereby displaying color and monochrome images of the affected part of the patient through different screens. It provides a photodynamic diagnostic device that can be checked at the same time.

The problem to be solved by the present invention is not limited to the problem (s) mentioned above, and other object (s) not mentioned will be clearly understood by those skilled in the art from the following description.

An optical dynamics diagnostic device according to an embodiment of the present invention includes a plurality of light sources for irradiating a plurality of light having different wavelengths; An objective lens disposed to face the target object; A zoom lens in which light reflected by the target object and passed through the objective lens is incident; A video member which photographs the light emitted from the zoom lens to generate an image of the target object differently for each wavelength, and separates and outputs the generated image for each wavelength into a plurality of channels; An eyepiece configured to visually observe an image of the object; And a plurality of display devices configured to display an image for each wavelength output for each channel.

The video member may include a beam splitter for simultaneously displaying the image of the target object formed through the objective lens on the eyepiece and the display device.

The beam splitter may be detachably formed.

The beam splitter is preferably designed in the shape of a Y-shaped easily removable on the back of the surgical microscope.

The Y-shaped beam splitter may be configured of an optical system using two cube-shaped beam splitters provided in optical paths corresponding to the left eye and the right eye, and four prism mirrors that change a movement path of the light passing through each beam splitter. have.

The beam splitter may include a filter for filtering light of a specific wavelength.

The video member may further include a camera unit photographing an image of the target object separated by the beam splitter and outputting the image for each wavelength to the plurality of display apparatuses through the respective channels.

The video member is an image of the target object, and generates an Indocyanine Green (ICG) image, an ICG color image, a 5-Aminolevulinic acid (5-ALA) image, and a 5-ALA color image for each of the wavelengths. Can be printed separately.

Specific details of other embodiments are included in the detailed description and the accompanying drawings.

According to an embodiment of the present invention, by converting the image for each wavelength separated by the beam splitter into image data through each camera to display on each display device, the color and black and white image for the affected part of the patient different screen You can check at the same time through this, it is possible to solve the existing problem that the information on the affected part is not visible because the color is mixed.

1 is a view illustrating a photodynamic diagnostic apparatus according to an embodiment of the present invention.

FIG. 2 is a diagram illustrating a configuration of a beam splitter provided in the video member of FIG. 1.

3 is an exemplary diagram illustrating a Y-shaped beam splitter applied to an embodiment of the present invention.

FIG. 4 is a diagram illustrating a configuration in which an image for each wavelength separated through a beam splitter is output and displayed for each channel according to an embodiment of the present invention.

* Description of the major symbols in the drawings *

a, b, c: light source

101: object

110: objective lens

120: zoom lens

130: video absent

135, 420: camera unit

140: eyepiece

150, 430: display device

210, 220, 230, 240, 300, 410: beam splitter

Advantages and / or features of the present invention and methods for achieving them will become apparent with reference to the embodiments described below in detail in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but may be implemented in various different forms, only the present embodiments to make the disclosure of the present invention complete, and common knowledge in the art to which the present invention pertains. It is provided to fully inform the person having the scope of the invention, which is defined only by the scope of the claims. Like reference numerals refer to like elements throughout.

Hereinafter, with reference to the accompanying drawings will be described embodiments of the present invention;

Referring to FIG. 1, the photodynamic diagnosis apparatus 100 according to an exemplary embodiment may include a plurality of light sources a, b, and c, an objective lens 110, a zoom lens 120, a video member 130, The eyepiece 140 may include a plurality of display devices 150.

The plurality of light sources a, b, and c irradiate a plurality of lights having different wavelengths. The irradiated plurality of lights may be guided to the object lens 110 and irradiated onto the object object 101 which is in close proximity to the object lens 110.

In this case, the light sources a, b, and c may irradiate light in a wavelength band that reacts with fluorescent materials such as IGC (Indocyanine green) and 5-ALA (5-Aminolevulinic acid). In addition, the plurality of light sources a, b, and c may radiate white light, which is a wavelength band of visible light.

In Figure 1, the light source (a) can be irradiated with visible light visible through the halogen, etc., the light source (b) responds to 5-ALA that can see the affected area, for example tumor (tumor) tissue The light source (c) may be irradiated with light in a wavelength band (for example, 410 nm), and the light source (c) may irradiate light in a wavelength band (for example, 760 nm) in response to an ICG for viewing an affected part, for example, vascular tissue. Confirmation of where the tumor is roughly can be made through the light source (b), and the actual surgery reports the visible light of the light source (a). The light source a is not limited to visible light and may irradiate near infrared rays.

For reference, the near-infrared ray means the light having the shortest wavelength among infrared rays whose wavelength range is 750 nm or more. Since near-infrared rays are beyond the visible range of the human eye, there are almost no side effects such as glare or delayed recovery after surgery compared to visible rays of the same amount of energy, for example in ophthalmic surgery.

The objective lens 110 is disposed to face the target object 101. Here, the target object 101 may be the affected part of the patient. For example, in the case of ophthalmic surgery, the target object 101 may be the eye of the patient.

The objective lens 110 receives a plurality of lights irradiated from the plurality of light sources a, b, and c so that the objective lens 110 may be irradiated to the affected part of the patient. In this case, since the light sources a, b, and c have different wavelengths, light of various wavelength bands may be irradiated to the affected part of the patient through the objective lens 110.

Light that is reflected by the target object 101 and passes through the objective lens 110 is incident on the zoom lens 120. The zoom lens 120 may enlarge or reduce the incident light through a zoom in or zoom out function.

The video member 130 photographs the light emitted from the zoom lens 120 to generate an image of the object 101 differently for each wavelength, and separates the generated image for each wavelength into a plurality of channels. Output

To this end, the video member 130 may include

beam splitters

210, 220, 230, and 240, as shown in FIG. 2.

The

beam splitters

210, 220, 230, and 240 separate the image of the target object 101 formed through the objective lens 110 for each of the wavelengths, and output the plurality of channels to the eyepiece 140. And simultaneously display image data of the target object 101 on the display device 150.

In FIG. 2, L1 and L2 are incident light through a light path corresponding to the left eye of a surgical microscope observer, and are separated into respective channels, and may represent an indocyanine green (ICG) image and an ICG color image, respectively. In addition, in FIG. 2, R1 and R2 are light incident through a light path corresponding to the right eye of a surgical microscope observer and separated into respective channels, and represent 5-ALA (5-Aminolevulinic acid) images and 5-ALA color images, respectively. Can be.

The

beam splitters

210, 220, 230, and 240 may be detachably formed on the surgical microscope. At this time, the

beam splitters

210, 220, 230, 240 is preferably designed in a Y-shape so that the detachable to the back of the surgical microscope.

3 is an exemplary view illustrating the Y-shaped beam splitter.

As shown in FIG. 3, the Y-shaped beam splitter 300 includes two cube-shaped

beam splitters

310 and 320 provided in an optical path corresponding to the left and right eyes, and the

beam splitters

310 and 320. An optical system may be configured by four prism mirrors 330 and 340 that change a moving path of light passing through the light.

In this case, although not shown in the figure, the Y-shaped beam splitter 300 may include a filter for filtering light having a specific wavelength. The Y-shaped beam splitter 300 may output light having a different wavelength to each channel through the filter.

Meanwhile, the video member 130 captures an image of the target object 101 separated by the

beam splitters

210, 220, 230, and 240 to display the image for each wavelength through the plurality of channels. The apparatus may further include a camera unit 135 output to the display device 150.

The video member 130 may separate an image of the target object 101 output through the camera unit 135 into the respective channels and output the divided images to the plurality of display apparatuses 150.

That is, the video member 130 generates an ICG image, an ICG color image, a 5-ALA image, and a 5-ALA color image for each wavelength as an image of the target object 101, and separates the image into the respective channels. You can print

The eyepiece 140 is formed to visually observe an image of the target object 101. To this end, the eyepiece 140 may be disposed at a position facing the video member 130.

The plurality of display devices 150 displays images for each wavelength output by the video member 130 for each channel. Hereinafter, a configuration of displaying an image for each wavelength for each channel will be described in detail with reference to FIG. 4.

Referring to FIG. 4, the image for each wavelength branched through the beam splitter 410 is input to the camera unit 420 through channels 1, 2, 3, and 4. That is, the image passing through the channel 1 is input to the camera 1 421, and the image passing through the channel 2 is input to the camera 2 422. In addition, the image passing through the channel 3 is input to the camera 3 (423), the image passing through the channel 4 is input to the camera 4 (424).

For example, the image input to the camera 1 421 may be an ICG image, and the image input to the camera 2 422 may be an ICG color image. In addition, an image input to the camera 3 423 may be a 5-ALA image, and an image input to the camera 4 424 may be a 5-ALA color image.

Images for each wavelength input to the camera unit 420 are output to the display device 430 and displayed. That is, the image input to the camera 1 421 is displayed through the monitor 1 431, and the image input to the camera 2 422 is displayed through the monitor 2 432. Also, the image input to the camera 3 423 is displayed through the monitor 343 3, and the image input to the camera 4 424 is displayed through the monitor 4 434.

As described above, according to the exemplary embodiment of the present invention, the image for each wavelength separated by the beam splitter (for example, L1, L2, R1, and R2 of FIG. 2) is converted into image data through each camera to each display apparatus. By displaying, the color and black and white image of the affected part of the patient can be checked at the same time through a different screen, through which the existing problem that the information on the affected part is not easily seen due to the mixed color.

While specific embodiments of the present invention have been described so far, various modifications are possible without departing from the scope of the present invention. Therefore, the scope of the present invention should not be limited to the described embodiments, but should be defined not only by the claims below, but also by the equivalents of the claims.

As described above, the present invention has been described by way of limited embodiments and drawings, but the present invention is not limited to the above-described embodiments, which can be variously modified and modified by those skilled in the art to which the present invention pertains. Modifications are possible. Accordingly, the spirit of the present invention should be understood only by the claims set forth below, and all equivalent or equivalent modifications thereof will belong to the scope of the present invention.

Claims

A plurality of light sources for irradiating a plurality of light having different wavelengths;

An objective lens disposed to face the target object;

A zoom lens in which light reflected by the target object and passed through the objective lens is incident;

A video member which photographs the light emitted from the zoom lens to generate an image of the target object differently for each wavelength, and separates and outputs the generated image for each wavelength into a plurality of channels;

An eyepiece configured to visually observe an image of the object; And

A plurality of display devices for displaying the image for each wavelength output for each channel

Photodynamic diagnostic device comprising a.
The method of claim 1,

The video member

A beam splitter for simultaneously displaying the image of the target object formed through the objective lens on the eyepiece and the display device

Photodynamic diagnostic device comprising a.
The method of claim 2,

The beam splitter

Photodynamic diagnostic device, characterized in that formed detachably.
The method of claim 3,

The beam splitter

A photodynamic diagnostic device characterized by being designed in a Y-shaped shape that is easily removable on the back side of a surgical microscope.
The method of claim 4, wherein

The Y-shaped beam splitter

And an optical system comprising two cube-shaped beam splitters provided in optical paths corresponding to the left eye and the right eye, and four prism mirrors for changing the movement paths of the light passing through the beam splitters.
The method of claim 2,

The beam splitter

And a filter for filtering light of a specific wavelength.
The method of claim 2,

The video member

A camera unit for capturing an image of the target object separated by the beam splitter and outputting the image for each wavelength to the plurality of display devices through the respective channels.

Photodynamic diagnostic device further comprising a.
The method of claim 1,

The video member

As an image of the target object, an ICG (Indocyanine Green) image, an ICG color image, a 5-ALA (5-Aminolevulinic acid) image, and a 5-ALA color image are generated for each wavelength and separated and output to each channel. Photodynamic diagnostic device, characterized in that.